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List of works by Joseph Heitman

A MAP kinase cascade composed of cell type specific and non-specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans

article

A Mep2-dependent transcriptional profile links permease function to gene expression during pseudohyphal growth in Saccharomyces cerevisiae

scientific article published on 23 April 2008

A PCR-based strategy to generate integrative targeting alleles with large regions of homology.

scientific article published in August 2002

A Sch9 protein kinase homologue controlling virulence independently of the cAMP pathway in Cryptococcus neoformans

A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans

scientific article published on 26 March 2009

A diverse population of Cryptococcus gattii molecular type VGIII in southern Californian HIV/AIDS patients

scientific article

A flucytosine-responsive Mbp1/Swi4-like protein, Mbs1, plays pleiotropic roles in antifungal drug resistance, stress response, and virulence of Cryptococcus neoformans

scientific article published on 11 November 2011

A genetic linkage map of Cryptococcus neoformans variety neoformans serotype D (Filobasidiella neoformans).

scientific article

A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes

scientific article

A non-canonical RNA degradation pathway suppresses RNAi-dependent epimutations in the human fungal pathogen Mucor circinelloides.

scientific article

A unique chromosomal rearrangement in the Cryptococcus neoformans var. grubii type strain enhances key phenotypes associated with virulence

scientific article published on 28 February 2012

A unique fungal two-component system regulates stress responses, drug sensitivity, sexual development, and virulence of Cryptococcus neoformans

scientific article

Adenylyl cyclase functions downstream of the Galpha protein Gpa1 and controls mating and pathogenicity of Cryptococcus neoformans

scientific article published on February 2002

Adenylyl cyclase-associated protein Aca1 regulates virulence and differentiation of Cryptococcus neoformans via the cyclic AMP-protein kinase A cascade

scientific article

Amt2 permease is required to induce ammonium-responsive invasive growth and mating in Cryptococcus neoformans

scientific article

An Antifungal Combination Matrix Identifies a Rich Pool of Adjuvant Molecules that Enhance Drug Activity against Diverse Fungal Pathogens

scientific article

An EcoRI-RsrI chimeric restriction endonuclease retains parental sequence specificity

scientific article published on 14 March 2007

Analysis of a food-borne fungal pathogen outbreak: virulence and genome of a Mucor circinelloides isolate from yogurt

scientific article

Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation

scientific article

Antifungal attributes of immunosuppressive agents: new paradigms in management and elucidating the pathophysiologic basis of opportunistic mycoses in organ transplant recipients

scientific article published on March 2004

Antifungal drug resistance evoked via RNAi-dependent epimutations

scientific article published on 27 July 2014

Antifungal management practices and evolution of infection in organ transplant recipients with cryptococcus neoformans infection

scientific article published in October 2005

Aspergillus fumigatus calcipressin CbpA is involved in hyphal growth and calcium homeostasis

scientific article published on 27 February 2009

Association of Calcineurin with the COPI Protein Sec28 and the COPII Protein Sec13 Revealed by Quantitative Proteomics ⬇️

scientific article published on October 3, 2011

Broad antifungal resistance mediated by RNAi-dependent epimutation in the basal human fungal pathogen Mucor circinelloides

scientific article published on 11 February 2019

Calcineurin Colocalizes with P-Bodies and Stress Granules during Thermal Stress in Cryptococcus neoformans ⬇️

scientific article published on July 1, 2011

Calcineurin Governs Thermotolerance and Virulence ofCryptococcus gattii ⬇️

scientific article published on March 1, 2013

Calcineurin Targets Involved in Stress Survival and Fungal Virulence

scientific article

Calcineurin controls drug tolerance, hyphal growth, and virulence in Candida dubliniensis

scientific article published on 29 April 2011

Calcineurin controls growth, morphology, and pathogenicity in Aspergillus fumigatus

scientific article

Calcineurin controls hyphal growth, virulence, and drug tolerance of Candida tropicalis

scientific article

Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach

scientific article published on 20 June 2016

Calcineurin inhibition or mutation enhances cell wall inhibitors against Aspergillus fumigatus

scientific article published on 14 May 2007

Calcineurin inhibitor agents interact synergistically with antifungal agents in vitro against Cryptococcus neoformans isolates: correlation with outcome in solid organ transplant recipients with cryptococcosis

scientific article

Calcineurin is essential for Candida albicans survival in serum and virulence

scientific article

Calcineurin is essential for survival during membrane stress in Candida albicans

scientific article

Calcineurin is required for Candida albicans to survive calcium stress in serum

scientific article published in September 2005

Calcineurin is required for pseudohyphal growth, virulence, and drug resistance in Candida lusitaniae

scientific article

Calcineurin localizes to the hyphal septum in Aspergillus fumigatus: implications for septum formation and conidiophore development

scientific article published on 7 July 2008

Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host-pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides

scientific article published on 25 May 2015

Calcineurin plays key roles in the dimorphic transition and virulence of the human pathogenic zygomycete Mucor circinelloides

scientific article

Calcineurin promotes infection of the cornea by Candida albicans and can be targeted to enhance fluconazole therapy

scientific article published on 21 August 2006

Calcineurin target CrzA regulates conidial germination, hyphal growth, and pathogenesis of Aspergillus fumigatus

scientific article published on 2 May 2008

Calcineurin, Mpk1 and Hog1 MAPK pathways independently control fludioxonil antifungal sensitivity in Cryptococcus neoformans

scientific article published in March 2006

Calcineurin-binding protein Cbp1 directs the specificity of calcineurin-dependent hyphal elongation during mating in Cryptococcus neoformans

scientific article published on September 2005

Calcineurin: a central controller of signalling in eukaryotes

scientific article published on April 2004

Calcium- and calcineurin-independent roles for calmodulin in Cryptococcus neoformans morphogenesis and high-temperature growth

scientific article

Calcofluor white combination antifungal treatments for Trichophyton rubrum and Candida albicans

scientific article

Carbonic anhydrase and CO2 sensing during Cryptococcus neoformans growth, differentiation, and virulence

scientific article published in November 2005

Cell biology. A fungal Achilles' heel

scientific article

Cell identity and sexual development in Cryptococcus neoformans are controlled by the mating-type-specific homeodomain protein Sxi1alpha

scientific article published on December 2002

Central nervous system cryptococcosis in solid organ transplant recipients: clinical relevance of abnormal neuroimaging findings

scientific article

Centromere deletion in Cryptococcus deuterogattii leads to neocentromere formation and chromosome fusions

scientific article published on 20 April 2020

Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response

scientific article published on April 2004

Characterizing the role of RNA silencing components in Cryptococcus neoformans

scientific article

Chlamydospore formation during hyphal growth in Cryptococcus neoformans

scientific article published on October 2005

Chromosomal sex-determining regions in animals, plants and fungi

scientific article

Chromosomal translocation and segmental duplication in Cryptococcus neoformans

scientific article published on February 2005

Clinical and environmental isolates of Cryptococcus gattii from Australia that retain sexual fecundity

scientific article published on August 2005

Clonality and recombination in genetically differentiated subgroups of Cryptococcus gattii

scientific article published on August 2005

Comparative Genome Analysis of Trichophyton rubrum and Related Dermatophytes Reveals Candidate Genes Involved in Infection

scientific article

Comparative analysis of calcineurin signaling betweenCandida dubliniensisandCandida albicans ⬇️

scientific article published on March 1, 2012

Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi

scientific article

Comparative transcriptome analysis of the CO2 sensing pathway via differential expression of carbonic anhydrase in Cryptococcus neoformans

scientific article

Comparative transcriptome analysis reveals novel roles of the Ras and cyclic AMP signaling pathways in environmental stress response and antifungal drug sensitivity in Cryptococcus neoformans

scientific article

Conservation, duplication, and loss of the Tor signaling pathway in the fungal kingdom ⬇️

scientific article published on September 23, 2010

Conserved elements of the RAM signaling pathway establish cell polarity in the basidiomycete Cryptococcus neoformans in a divergent fashion from other fungi

scientific article

Construction of a Recyclable Genetic Marker and Serial Gene Deletions in the Human Pathogenic Mucorales Mucor circinelloides

scientific article

Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in Candida glabrata

scientific article

Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms

scientific article published in December 2004

Convergent evolution of linked mating-type loci in basidiomycete fungi

scientific article published on 06 September 2019

Coping with stress: calmodulin and calcineurin in model and pathogenic fungi ⬇️

scientific article published on November 28, 2003

Correction to: The evolving species concepts used for yeasts: from phenotypes and genomes to speciation networks

scientific article published in 2021

Correction: Cryptococcal Cell Morphology Affects Host Cell Interactions and Pathogenicity.

scientific article published on 23 June 2010

Cryptococcal cell morphology affects host cell interactions and pathogenicity

scientific article (publication date: 2010)

Cryptococcal osteomyelitis in an adolescent survivor of T-cell acute lymphoblastic leukemia ⬇️

scientific article published on June 2015

Cryptococcosis Serotypes Impact Outcome and Provide Evidence of Cryptococcus neoformans Speciation

scientific article published on 9 June 2015

Cryptococcus deuterogattii VGIIa infection associated with travel to the Pacific Northwest outbreak region in an anti-GM-CSF autoantibody positive patient in the United States

Cryptococcus gattii VGIII isolates causing infections in HIV/AIDS patients in Southern California: identification of the local environmental source as arboreal

scientific article published in August 2014

Cryptococcus gattii genotype VGI infection in New England

scientific article published on December 2011

Cryptococcus gattii outbreak expands into the Northwestern United States with fatal consequences

scientific article

Cryptococcus gattii with bimorphic colony types in a dog in western Oregon: additional evidence for expansion of the Vancouver Island outbreak

scientific article published on January 2009

Cryptococcus gattii, no longer an accidental pathogen?

scientific article published on December 2012

Cryptococcus gattii: an emerging fungal pathogen infecting humans and animals ⬇️

scientific article published on June 1, 2011

Cryptococcus neoformans Copper Detoxification Machinery Is Critical for Fungal Virulence ⬇️

scientific article published on March 13, 2013

Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals

scientific article

Cryptococcus neoformans gene expression during murine macrophage infection

scientific article

Cryptococcus neoformans gene involved in mammalian pathogenesis identified by a Caenorhabditis elegans progeny-based approach

scientific article

Cryptococcus neoformans hyperfilamentous strain is hypervirulent in a murine model of cryptococcal meningoencephalitis

scientific article

Cryptococcus neoformans in organ transplant recipients: impact of calcineurin-inhibitor agents on mortality

scientific article

Cryptococcus neoformans isolates from transplant recipients are not selected for resistance to calcineurin inhibitors by current immunosuppressive regimens

scientific article

Cryptococcus neoformans mates on pigeon guano: implications for the realized ecological niche and globalization

scientific article

Cryptococcus neoformans virulence gene discovery through insertional mutagenesis

scientific article

Cryptococcus neoformans {alpha} strains preferentially disseminate to the central nervous system during coinfection

scientific article

Cryptococcus neoformans: Budding Yeast and Dimorphic Filamentous Fungus

Cyclic AMP-dependent protein kinase catalytic subunits have divergent roles in virulence factor production in two varieties of the fungal pathogen Cryptococcus neoformans

scientific article published on February 2004

Cyclophilin A is localized to the nucleus and controls meiosis in Saccharomyces cerevisiae

scientific article

Cyclophilin B escorts the hepatitis C virus RNA polymerase: a viral achilles heel?

scientific article

Deciphering the model pathogenic fungus Cryptococcus neoformans

scientific article

Deletion of Cryptococcus neoformans AIF ortholog promotes chromosome aneuploidy and fluconazole-resistance in a metacaspase-independent manner

scientific article

Development of an aerosol model of Cryptococcus reveals humidity as an important factor affecting the viability of Cryptococcus during aerosolization

scientific article

Diploids in the Cryptococcus neoformans serotype A population homozygous for the alpha mating type originate via unisexual mating

scientific article

Discovery of a modified tetrapolar sexual cycle in Cryptococcus amylolentus and the evolution of MAT in the Cryptococcus species complex

scientific article

Disruption of ergosterol biosynthesis confers resistance to amphotericin B in Candida lusitaniae

scientific article published on September 2003

Dissecting the Roles of the Calcineurin Pathway in Unisexual Reproduction, Stress Responses, and Virulence in Cryptococcus deneoformans

scientific article published on 12 December 2017

Distinct and redundant roles of exonucleases in Cryptococcus neoformans: implications for virulence and mating

scientific article

Divergence of protein kinase A catalytic subunits in Cryptococcus neoformans and Cryptococcus gattii illustrates evolutionary reconfiguration of a signaling cascade

scientific article published on 22 December 2006

Dynamic duo takes down fungal villains

scholarly article

Dynamics of parasitophorous vacuoles formed by the microsporidian pathogen Encephalitozoon cuniculi

scientific article

Eca1, a sarcoplasmic/endoplasmic reticulum Ca2+-ATPase, is involved in stress tolerance and virulence in Cryptococcus neoformans

scientific article published on 14 May 2007

Ecogenomics of Human and Animal Basidiomycetous Yeast Pathogens

article

Elucidating the Candida albicans calcineurin signaling cascade controlling stress response and virulence

scientific article published on 13 September 2009

Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformans

scientific article

Emergence and pathogenicity of highly virulent Cryptococcus gattii genotypes in the northwest United States

scientific article

Endolysosomal membrane trafficking complexes drive nutrient-dependent TORC1 signaling to control cell growth in Saccharomyces cerevisiae

scientific article published on 10 February 2014

Endosymbiosis: the evil within

scientific article published on June 2007

Enzymes that Counteract Nitrosative Stress Promote Fungal Virulence ⬇️

scientific article published on November 11, 2003

Epidemiology and Evolution of Fungal Pathogens in Plants and Animals

article

Epigenetic dynamics of centromeres and neocentromeres in Cryptococcus deuterogattii

scientific article published on 31 August 2021

Ergosterol biosynthesis inhibitors become fungicidal when combined with calcineurin inhibitors against Candida albicans, Candida glabrata, and Candida krusei

scientific article

Erratum for Ianiri et al., "FKBP12-Dependent Inhibition of Calcineurin Mediates Immunosuppressive Antifungal Drug Action in Malassezia".

scientific article published on 5 December 2017

Eukaryotic Sexual Reproduction Evoked "with a Little Help from My Friends".

scientific article published in September 2017

Evidence of sexual recombination among Cryptococcus neoformans serotype A isolates in sub-Saharan Africa

scientific article published on December 2003

Evolution of eukaryotic microbial pathogens via covert sexual reproduction

scientific article

Evolution of fungal sex chromosomes

scientific article

Evolution of fungal sexual reproduction ⬇️

scientific article published on October 25, 2012

Evolution of pathogenicity and sexual reproduction in eight Candida genomes

scientific article

Evolution of sex: mating rituals of a pre-metazoan

scientific article published in November 2013

Evolution of sexual reproduction: a view from the Fungal Kingdom supports an evolutionary epoch with sex before sexes

scientific article published on December 2015

Evolution of the mating type locus: insights gained from the dimorphic primary fungal pathogens Histoplasma capsulatum, Coccidioides immitis, and Coccidioides posadasii

scientific article published on 2 March 2007

Evolution of the sex-related locus and genomic features shared in microsporidia and fungi

scientific article

Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex.

scientific article

Expansion of Signal Transduction Pathways in Fungi by Extensive Genome Duplication

scientific article

FKBP12 controls aspartate pathway flux in Saccharomyces cerevisiae to prevent toxic intermediate accumulation

scientific article

FKBP12 is the only FK506 binding protein mediating T-cell inhibition by the immunosuppressant FK506.

scientific article published in June 2002

FKBP12-Dependent Inhibition of Calcineurin Mediates Immunosuppressive Antifungal Drug Action in Malassezia

scientific article published on 24 October 2017

Ferrochelatase is a conserved downstream target of the blue light-sensing White collar complex in fungi

scientific article (publication date: August 2010)

First contemporary case of human infection with Cryptococcus gattii in Puget Sound: evidence for spread of the Vancouver Island outbreak

scientific article published on 27 June 2007

First reported case of Cryptococcus gattii in the Southeastern USA: implications for travel-associated acquisition of an emerging pathogen

scientific article

From Two to One: Unipolar Sexual Reproduction

scientific article

Function of Cryptococcus neoformans KAR7 ( SEC66 ) in Karyogamy during Unisexual and Opposite-Sex Mating ⬇️

scientific article published on April 27, 2012

Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae

scientific article published in Journal of Biological Chemistry

Fungal Pathogenesis: Gene Clusters Unveiled as Secrets within the Ustilago maydis Code

article

Fungal genome and mating system transitions facilitated by chromosomal translocations involving intercentromeric recombination

scientific article published on 11 August 2017

Fungal genome sequencing and bioenergy

article

Fungal horizons: the Asilomar Fungal Genetics Conference 2007.

scientific article published on 26 September 2007

Fungal mating-type loci

scientific article published on October 2003

Fungal mating: Candida albicans flips a switch to get in the mood

scientific article

G protein signaling governing cell fate decisions involves opposing Galpha subunits in Cryptococcus neoformans

scientific article

G protein-coupled receptor Gpr4 senses amino acids and activates the cAMP-PKA pathway in Cryptococcus neoformans

scientific article

Galleria mellonella as a model system to study Cryptococcus neoformans pathogenesis

scientific article published on July 2005

Galpha subunit Gpa2 recruits kelch repeat subunits that inhibit receptor-G protein coupling during cAMP-induced dimorphic transitions in Saccharomyces cerevisiae

scientific article

Gene Function Analysis in the Ubiquitous Human Commensal and Pathogen Malassezia Genus

scientific article (publication date: 29 November 2016)

Gene Network Polymorphism Illuminates Loss and Retention of Novel RNAi Silencing Components in the Cryptococcus Pathogenic Species Complex

scientific article

Gene conversion occurs within the mating-type locus of Cryptococcus neoformans during sexual reproduction

scientific article

Generation of genetic diversity in microsporidia via sexual reproduction and horizontal gene transfer

scientific article published on September 2009

Generators of phenotypic diversity in the evolution of pathogenic microorganisms

scientific article

Genetic Diversity and Genomic Plasticity ofCryptococcus neoformansAD Hybrid Strains ⬇️

scientific article published on January 1, 2012

Genetic and epigenetic engines of diversity in pathogenic microbes

scientific article

Genetic and genomic analyses reveal boundaries between species closely related to Cryptococcus pathogens

Genetic circuits that govern bisexual and unisexual reproduction in Cryptococcus neoformans

scientific article

Genetics of Cryptococcus neoformans

scientific article

Genome Evolution and Innovation across the Four Major Lineages of Cryptococcus gattii ⬇️

scientific article

Genomic insights into the atopic eczema-associated skin commensal yeast Malassezia sympodialis

scientific article published on 22 January 2013

Genus-Wide Comparative Genomics of Malassezia Delineates Its Phylogeny, Physiology, and Niche Adaptation on Human Skin

scientific article published on 5 November 2015

Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata

scientific article

Good fungi gone bad: the corruption of calcineurin

scientific article

HGT in the human and skin commensal Malassezia: A bacterially derived flavohemoglobin is required for NO resistance and host interaction

scientific article published on 23 June 2020

Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections

scientific article published on June 2007

Highly recombinant VGII Cryptococcus gattii population develops clonal outbreak clusters through both sexual macroevolution and asexual microevolution

scientific article

Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling

scientific article published on 26 March 2009

Identification of Cryptococcus neoformans temperature-regulated genes with a genomic-DNA microarray

scientific article published on October 2004

Identification of ENA1 as a virulence gene of the human pathogenic fungus Cryptococcus neoformans through signature-tagged insertional mutagenesis

scientific article

Identification of the mating-type (MAT) locus that controls sexual reproduction of Blastomyces dermatitidis

scientific article published on 9 November 2012

Identification of the sex genes in an early diverged fungus

scientific article

Immunotherapy with tacrolimus (FK506) does not select for resistance to calcineurin inhibitors in Candida albicans isolates from liver transplant patients

scientific article

Impact of ammonium permeases mepA, mepB, and mepC on nitrogen-regulated secondary metabolism in Fusarium fujikuroi

scientific article published on 14 December 2007

Impact of mating type, serotype, and ploidy on the virulence of Cryptococcus neoformans

scientific article published on 21 April 2008

In vitro interactions between antifungals and immunosuppressants against Aspergillus fumigatus

scientific article published on May 2004

In vitro interactions between antifungals and immunosuppressants against Aspergillus fumigatus isolates from transplant and nontransplant patients

scientific article published on December 2004

Interaction between genetic background and the mating-type locus in Cryptococcus neoformans virulence potential

scientific article

Investigation of the basis of virulence in serotype A strains of Cryptococcus neoformans from apparently immunocompetent individuals

scientific article published on 19 May 2004

Is sex necessary?

scientific article

Isolates of Cryptococcus neoformans from infected animals reveal genetic exchange in unisexual, alpha mating type populations

scientific article published on 13 June 2008

Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis

scientific article

Know Your Enemy: How to Build and Vanquish a Global Fungal Scourge ⬇️

scientific article published on October 14, 2011

Light controls growth and development via a conserved pathway in the fungal kingdom

scientific article

Long transposon-rich centromeres in an oomycete reveal divergence of centromere features in Stramenopila-Alveolata-Rhizaria lineages

scientific article published on 09 March 2020

Loss of allergen 1 confers a hypervirulent phenotype that resembles mucoid switch variants of Cryptococcus neoformans

scientific article published on 27 October 2008

Magnificent seven: roles of G protein-coupled receptors in extracellular sensing in fungi

scientific article

Malassezia fungi are specialized to live on skin and associated with dandruff, eczema, and other skin diseases

scientific article

Many globally isolated AD hybrid strains of Cryptococcus neoformans originated in Africa

scientific article

Mating-type locus of Cryptococcus neoformans: a step in the evolution of sex chromosomes

scientific article

Mating-type-specific and nonspecific PAK kinases play shared and divergent roles in Cryptococcus neoformans

scientific article

Mechanistic plasticity of sexual reproduction and meiosis in the Candida pathogenic species complex

scientific article published on 14 May 2009

Microbial genetics: Love the one you're with

scientific article published in August 2009

Microbial pathogens in the fungal kingdom ⬇️

scientific article (publication date: March 2011)

Microsporidia evolved from ancestral sexual fungi

scientific article

Molecular and Genetic Evidence for a Tetrapolar Mating System in the Basidiomycetous Yeast Kwoniella mangrovensis and Two Novel Sibling Species ⬇️

scientific article published on March 22, 2013

Molecular evidence that the range of the Vancouver Island outbreak of Cryptococcus gattii infection has expanded into the Pacific Northwest in the United States

scientific article

Morphological and genomic characterization of Filobasidiella depauperata: a homothallic sibling species of the pathogenic cryptococcus species complex

scientific article

Natural mismatch repair mutations mediate phenotypic diversity and drug resistance in Cryptococcus deuterogattii

scientific article published on 26 September 2017

Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans

scientific article

New facets of antifungal therapy

scientific article published on 7 November 2016

Novel gene functions required for melanization of the human pathogenCryptococcus neoformans

article

Nutrient and Stress Sensing in Pathogenic Yeasts

scientific article published in 2019

On the Discovery of TOR As the Target of Rapamycin

scientific article

Orchestration of sexual reproduction and virulence by the fungal mating-type locus

scientific article (publication date: December 2008)

Ordered kinetochore assembly in the human-pathogenic basidiomycetous yeast Cryptococcus neoformans

scientific article published on October 2013

Organization and evolutionary trajectory of the mating type (MAT) locus in dermatophyte and dimorphic fungal pathogens

scientific article

Origins of eukaryotic sexual reproduction

scientific article published on March 2014

Outbreak of Invasive Wound Mucormycosis in a Burn Unit Due to Multiple Strains of Mucor circinelloides f. circinelloides Resolved by Whole-Genome Sequencing

scientific article published on 24 April 2018

PAK kinases Ste20 and Pak1 govern cell polarity at different stages of mating in Cryptococcus neoformans

scientific article published on 28 July 2004

PRM1 and KAR5 function in cell-cell fusion and karyogamy to drive distinct bisexual and unisexual cycles in the Cryptococcus pathogenic species complex

scientific article

Parallels in intercellular communication in oomycete and fungal pathogens of plants and humans

scientific article

Pde1 phosphodiesterase modulates cyclic AMP levels through a protein kinase A-mediated negative feedback loop in Cryptococcus neoformans

scientific article published on December 2005

Pearls collections: What we can learn about infectious disease and cancer.

scientific article

Peroxisome function regulates growth on glucose in the basidiomycete fungus Cryptococcus neoformans

scientific article published on 13 October 2006

Pheromones stimulate mating and differentiation via paracrine and autocrine signaling in Cryptococcus neoformans

scientific article

Phospholipid-binding protein Cts1 controls septation and functions coordinately with calcineurin in Cryptococcus neoformans

scientific article

Photosensing fungi: phytochrome in the spotlight

scientific article

Phycomyces MADB interacts with MADA to form the primary photoreceptor complex for fungal phototropism

scholarly article

Phylogeny and phenotypic characterization of pathogenic Cryptococcus species and closely related saprobic taxa in the Tremellales

scientific article

Physical maps for genome analysis of serotype A and D strains of the fungal pathogen Cryptococcus neoformans

scientific article published on September 2002

Plants promote mating and dispersal of the human pathogenic fungus Cryptococcus

scientific article

Pleiotropic roles of the Msi1-like protein Msl1 in Cryptococcus neoformans

scientific article published on 5 October 2012

Polyporales genomes reveal the genetic architecture underlying tetrapolar and bipolar mating systems.

scientific article published on 8 August 2013

Population Genomics Of Cryptococcus neoformans var. grubii Reveals New Biogeographic Relationships And Finely Maps Hybridization

scientific article published in May 2017

Population genomics and the evolution of virulence in the fungal pathogen Cryptococcus neoformans

scientific article

Posaconazole exhibits in vitro and in vivo synergistic antifungal activity with caspofungin or FK506 against Candida albicans

scientific article

Profiling a killer, the development of Cryptococcus neoformans

scientific article published on 04 July 2011

Prolyl isomerases in yeast

scientific article published in September 2004

Protein kinase A operates a molecular switch that governs yeast pseudohyphal differentiation

scientific article

Pseudohyphal growth of Cryptococcus neoformans is a reversible dimorphic transition in response to ammonium that requires Amt1 and Amt2 ammonium permeases ⬇️

scientific article published on September 21, 2012

Pulmonary cryptococcosis in solid organ transplant recipients: clinical relevance of serum cryptococcal antigen

scientific article

RNAi function, diversity, and loss in the fungal kingdom

scientific article published on December 2013

RNAi is a critical determinant of centromere evolution in closely related fungi

scientific article published on 5 March 2018

Rapamycin Exerts Antifungal Activity In Vitro and In Vivo against Mucor circinelloides via FKBP12-Dependent Inhibition of Tor ⬇️

scientific article published on December 30, 2011

Ras1 and Ras2 contribute shared and unique roles in physiology and virulence of Cryptococcus neoformans

scientific article published on January 2002

Ras1 controls pheromone expression and response during mating in Cryptococcus neoformans

scientific article published in February 2003

Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: implications for an outbreak on Vancouver Island, Canada

scientific article published on October 2003

Recombination hotspots flank the Cryptococcus mating-type locus: implications for the evolution of a fungal sex chromosome

scientific article

Remodeling of global transcription patterns of Cryptococcus neoformans genes mediated by the stress-activated HOG signaling pathways

scientific article published on 19 June 2009

Role of an Expanded Inositol Transporter Repertoire in Cryptococcus neoformans Sexual Reproduction and Virulence ⬇️

scientific article published on May 18, 2010

Sensing the environment: lessons from fungi

scientific article published on January 2007

Septins enforce morphogenetic events during sexual reproduction and contribute to virulence of Cryptococcus neoformans

scientific article published on 25 November 2009

Sex and virulence of human pathogenic fungi

scientific article

Sex in fungi

scientific article published on 13 September 2011

Sex in the Mucoralean fungi

scientific article published on 31 August 2014

Sex-Induced Silencing Operates During Opposite-Sex and Unisexual Reproduction in Cryptococcus neoformans ⬇️

scientific article published on February 1, 2013

Sex-induced silencing defends the genome of Cryptococcus neoformans via RNAi

scientific article

Sex-specific homeodomain proteins Sxi1alpha and Sxi2a coordinately regulate sexual development in Cryptococcus neoformans

scientific article

Sexual Reproduction in Dermatophytes

scientific article

Sexual Reproduction of Cryptococcus

Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates

scientific article published on September 2003

Sexual reproduction and the evolution of microbial pathogens

scientific article

Sexual reproduction between partners of the same mating type in Cryptococcus neoformans

scientific article (publication date: 21 April 2005)

Sexual reproduction of human fungal pathogens

scientific article published on August 2014

Should Y stay or should Y go: the evolution of non-recombining sex chromosomes

scientific article published on 05 September 2012

Signal-transduction cascades as targets for therapeutic intervention by natural products

article

Signaling cascades as drug targets in model and pathogenic fungi

scientific article published on August 2008

Signalling pathways in the pathogenesis of Cryptococcus

scientific article published on 19 December 2008

Specialization of the HOG pathway and its impact on differentiation and virulence of Cryptococcus neoformans

scientific article

Sporangiospore Size Dimorphism Is Linked to Virulence of Mucor circinelloides ⬇️

scientific article published on June 16, 2011

Spores as infectious propagules of Cryptococcus neoformans

scientific article

Ssk2 mitogen-activated protein kinase kinase kinase governs divergent patterns of the stress-activated Hog1 signaling pathway in Cryptococcus neoformans

scientific article published on 19 October 2007

Structure, function, and phylogeny of the mating locus in the Rhizopus oryzae complex

scientific article

Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function

scientific article published on 26 April 2016

Surfactant Protein D Facilitates Cryptococcus neoformans Infection ⬇️

scientific article published on April 30, 2012

Surfactant protein D binding to Aspergillus fumigatus hyphae is calcineurin-sensitive

scientific article published on June 2010

Surfactant protein D increases phagocytosis of hypocapsular Cryptococcus neoformans by murine macrophages and enhances fungal survival

scientific article

Synergistic effect of calcineurin inhibitors and fluconazole against Candida albicans biofilms

scientific article published on 7 January 2008

Synthesis and antifungal activities of miltefosine analogs

scientific article published on 06 July 2013

Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans

scientific article published on 28 September 2016

Systematic functional profiling of transcription factor networks in Cryptococcus neoformans

scientific article

Targeting the calcineurin pathway enhances ergosterol biosynthesis inhibitors against Trichophyton mentagrophytes in vitro and in a human skin infection model

scientific article

Teaching old drugs new tricks: reincarnating immunosuppressants as antifungal drugs.

scientific article

The C2 Domain Protein Cts1 Functions in the Calcineurin Signaling Circuit during High-Temperature Stress Responses in Cryptococcus neoformans ⬇️

scientific article published on October 14, 2011

The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function

scientific article

The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits

scientific article

The Mating-Type Locus of Cryptococcus: Evolution of Gene Clusters Governing Sex Determination and Sexual Reproduction from the Phylogenomic Perspective

article

The Pheromone and Pheromone Receptor Mating-Type Locus Is Involved in Controlling Uniparental Mitochondrial Inheritance in Cryptococcus

scientific article published on 30 December 2019

The Phycomyces madA gene encodes a blue-light photoreceptor for phototropism and other light responses

scholarly article

The RGS protein Crg2 regulates both pheromone and cAMP signalling in Cryptococcus neoformans

scientific article published on 27 August 2008

The Rise of Fungi: A Report on the CIFAR Program Fungal Kingdom: Threats & Opportunities Inaugural Meeting

scientific article published on 01 June 2020

The alpha-specific cell identity factor Sxi1alpha is not required for virulence of Cryptococcus neoformans

scientific article

The biology of the Cryptococcus neoformans species complex

scientific article

The calcineurin target, Crz1, functions in azole tolerance but is not required for virulence of Candida albicans

scientific article

The cyclophilins

scientific article

The evolution of sex: a perspective from the fungal kingdom

scientific article (publication date: June 2010)

The evolving species concepts used for yeasts: from phenotypes and genomes to speciation networks

scientific article published in 2021

The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans

scientific article

The human fungal pathogen Cryptococcus can complete its sexual cycle during a pathogenic association with plants

scientific article published in June 2007

The kelch proteins Gpb1 and Gpb2 inhibit Ras activity via association with the yeast RasGAP neurofibromin homologs Ira1 and Ira2.

scientific article

The mating type locus (MAT) and sexual reproduction of Cryptococcus heveanensis: insights into the evolution of sex and sex-determining chromosomal regions in fungi

scientific article

The mating type-specific homeodomain genes SXI1 alpha and SXI2a coordinately control uniparental mitochondrial inheritance in Cryptococcus neoformans

scientific article published in March 2007

The protein kinase Tor1 regulates adhesin gene expression in Candida albicans

scientific article

The virulence of human pathogenic fungi: notes from the South of France

scientific article published on August 2007

Tornadic Shear Stress Induces a Transient, Calcineurin-Dependent Hypervirulent Phenotype in Mucorales Molds

scientific article published on 30 June 2020

Tracing Genetic Exchange and Biogeography of Cryptococcus neoformans var. grubii at the Global Population Level.

scientific article published on 5 July 2017

Transcription factors Mat2 and Znf2 operate cellular circuits orchestrating opposite- and same-sex mating in Cryptococcus neoformans

scientific article (publication date: May 2010)

Transcriptional network of multiple capsule and melanin genes governed by the Cryptococcus neoformans cyclic AMP cascade

scientific article

Transgene induced co-suppression during vegetative growth in Cryptococcus neoformans

scientific article

Transitions in sexuality: recapitulation of an ancestral tri- and tetrapolar mating system in Cryptococcus neoformans

scientific article published on 22 August 2008

Transmission of Hypervirulence traits via sexual reproduction within and between lineages of the human fungal pathogen cryptococcus gattii

scientific article

Transposon mobilization in the human fungal pathogen Cryptococcus is mutagenic during infection and promotes drug resistance in vitro

scientific article published on 17 April 2020

Trimorphic stepping stones pave the way to fungal virulence

scholarly article

Unique evolution of the UPR pathway with a novel bZIP transcription factor, Hxl1, for controlling pathogenicity of Cryptococcus neoformans

scientific article

Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans

scientific article (publication date: September 2013)

Unisexual reproduction

scientific article published on January 2014

Unisexual reproduction drives evolution of eukaryotic microbial pathogens

scientific article

Unisexual reproduction enhances fungal competitiveness by promoting habitat exploration via hyphal growth and sporulation

scientific article published on 21 June 2013

Unisexual reproduction of Cryptococcus gattii

scientific article

Unisexual reproduction promotes competition for mating partners in the global human fungal pathogen Cryptococcus deneoformans

scientific article published on 19 September 2019

Unisexual reproduction reverses Muller's ratchet

scientific article

Unisexual versus bisexual mating in Cryptococcus neoformans: Consequences and biological impacts

scientific article

Unseen sex in ancient virgin fungi

scientific article published on January 2014

Virulence attributes and hyphal growth of C. neoformans are quantitative traits and the MATalpha allele enhances filamentation

scientific article

Whole-Genome Analysis Illustrates Global Clonal Population Structure of the Ubiquitous Dermatophyte Pathogen Trichophyton rubrum.

scientific article published on 21 February 2018

Yeast diversity sampling on the San Juan Islands reveals no evidence for the spread of the Vancouver Island Cryptococcus gattii outbreak to this locale

scientific article published in June 2006

alpha AD alpha hybrids of Cryptococcus neoformans: evidence of same-sex mating in nature and hybrid fitness

scientific article

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