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List of works by Anne-Claude Gingras

(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells

scientific article

4E binding proteins inhibit the translation factor eIF4E without folded structure

scientific article published on 01 January 1998

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

scientific article (publication date: 15 February 1998)

4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family

scientific article

A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface

scientific journal article

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

scientific article published on 21 December 2016

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein

scientific article

A Versatile Lentiviral Delivery Toolkit for Proximity-dependent Biotinylation in Diverse Cell Types.

scientific article published on 10 July 2018

A Web Resource for Improved Analysis of AP-MS Protein Interaction Data

scientific article published in May 2013

A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis

scientific article published on 17 April 2019

A cost-benefit analysis of multidimensional fractionation of affinity purification-mass spectrometry samples

scientific article published on June 2011

A global genetic interaction network maps a wiring diagram of cellular function

scientific article

A global protein kinase and phosphatase interaction network in yeast.

scientific article

A global regulatory mechanism for activating an exon network required for neurogenesis

scientific article published on 11 September 2014

A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency

scientific article

A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development

scientific article

A novel mechanism for SUMO system control: regulated Ulp1 nucleolar sequestration

scientific article

A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblasts.

scientific article published on 6 March 2012

A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity

scientific article

A potential role for extracellular signal-regulated kinases in prostaglandin F2alpha-induced protein synthesis in smooth muscle cells

scientific article published on 01 April 1999

A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability.

scientific article published on 14 December 2016

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways

scientific article

A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus

scientific article

A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination

scientific article published on 23 March 2022

A web-tool for visualizing quantitative protein-protein interaction data.

scientific article

AIRE is a critical spindle-associated protein in embryonic stem cells

scientific article published on 25 July 2017

AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network

scientific article published on 17 July 2020

Acetylation of PCNA Sliding Surface by Eco1 Promotes Genome Stability through Homologous Recombination

scientific article published on 16 November 2016

Activation of GCN2 in UV-irradiated cells inhibits translation

scientific journal article

Activation of Mitochondrial Protein Phosphatase SLP2 by MIA40 Regulates Seed Germination.

scientific article

Adenovirus infection inactivates the translational inhibitors 4E-BP1 and 4E-BP2

scientific article published on 01 October 1997

Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1.

scientific article

Advances in protein complex analysis using mass spectrometry

scientific article

Affinity-purification coupled to mass spectrometry: basic principles and strategies

scientific article published on May 2012

Affinity-purification mass spectrometry (AP-MS) of serine/threonine phosphatases

scientific article

An alternative splicing event amplifies evolutionary differences between vertebrates

scientific article

An open invitation to the Understudied Proteins Initiative

scientific article published on 9 May 2022

Analysis of protein complexes through model-based biclustering of label-free quantitative AP-MS data

scientific article

Analysis of protein complexes using mass spectrometry

scientific article

Analyzing protein-protein interactions from affinity purification-mass spectrometry data with SAINT

scientific article

Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching

scientific article

Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation

scientific article published on 29 June 2015

Author Correction: Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

scientific article published on 01 March 2020

Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

scientific article published on 26 May 2020

BRPF3-HBO1 regulates replication origin activation and histone H3K14 acetylation

scientific article published on 30 November 2015

Beyond hairballs: The use of quantitative mass spectrometry data to understand protein-protein interactions

scientific article

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates

scientific article

Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins

scientific article

C. elegans SUP-46, an HNRNPM family RNA-binding protein that prevents paternally-mediated epigenetic sterility

scientific article

CCM-3 Promotes C. elegans Germline Development by Regulating Vesicle Trafficking Cytokinesis and Polarity

scientific article

CCM-3/STRIPAK promotes seamless tube extension through endocytic recycling

scientific article published on 6 March 2015

CCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization

scientific article

CEP19 cooperates with FOP and CEP350 to drive early steps in the ciliogenesis programme.

scientific article

CEP192 interacts physically and functionally with the K63-deubiquitinase CYLD to promote mitotic spindle assembly

scientific article published on 16 August 2012

CLMSVault: A Software Suite for Protein Cross-Linking Mass-Spectrometry Data Analysis and Visualization.

scientific article published on 5 June 2017

Cap-binding protein 4EHP effects translation silencing by microRNAs

scientific article published on 9 May 2017

Cell cycle-regulated oscillator coordinates core histone gene transcription through histone acetylation

scientific article

Cloning and characterization of 4EHP, a novel mammalian eIF4E-related cap-binding protein

scientific article

Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor.

scientific article

Compliance Checklists No Longer Required at Initial Manuscript Submission

scientific article published on 16 March 2020

Conserved Asf1-importin β physical interaction in growth and sexual development in the ciliate Tetrahymena thermophila

scientific article published on 11 October 2013

Construction of human activity-based phosphorylation networks.

scientific article

Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs

scientific article published on 30 May 2008

Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C.

scientific article published on 18 March 2016

DIA-Umpire: comprehensive computational framework for data-independent acquisition proteomics

scientific article

Data Independent Acquisition analysis in ProHits 4.0.

scientific article

Drafting the CLN3 protein interactome in SH-SY5Y human neuroblastoma cells: a label-free quantitative proteomics approach.

scientific article

Dual action antifungal small molecule modulates multidrug efflux and TOR signaling

scientific article

Endosomal sorting of VAMP3 is regulated by PI4K2A.

scientific article

Eukaryotic translation initiation factor 4E availability controls the switch between cap-dependent and internal ribosomal entry site-mediated translation

scientific article

Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.

scientific article

Exploring genetic suppression interactions on a global scale

scientific article

Functional characterization of a PROTAC directed against BRAF mutant V600E

scientific article published on 10 August 2020

Gaining an Easy Visual Grasp on MCP Content.

scientific article published in July 2018

Gastrin induces phosphorylation of eIF4E binding protein 1 and translation initiation of ornithine decarboxylase mRNA ⬇️

scientific article published on April 30, 1998

Getting to know the neighborhood: using proximity-dependent biotinylation to characterize protein complexes and map organelles

scientific article published on 17 November 2018

Global gene deletion analysis exploring yeast filamentous growth

scientific article published on 01 September 2012

Global interactomics uncovers extensive organellar targeting by Zika virus

article

HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity

scientific article

HELB Is a Feedback Inhibitor of DNA End Resection

scientific journal article

Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity

scientific article published on 19 January 2016

Hierarchical phosphorylation of the translation inhibitor 4E-BP1

scientific article

High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies.

scientific article published on 25 January 2018

High-resolution protein interaction map of the Drosophila melanogaster p38 mitogen-activated protein kinases reveals limited functional redundancy

scientific article

Histone recognition and large-scale structural analysis of the human bromodomain family

scientific article

History of protein-protein interactions: from egg-white to complex networks

scientific article published on May 2012

Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E

scientific article

Identification and characterization of AtI-2, an Arabidopsis homologue of an ancient protein phosphatase 1 (PP1) regulatory subunit

scientific article published on April 2011

Identification of putative androgen receptor interaction protein modules: cytoskeleton and endosomes modulate androgen receptor signaling in prostate cancer cells

scientific article published on 18 October 2006

In planta proximity dependent biotin identification (BioID).

scientific article published on 15 June 2018

Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors

scientific article published on 20 September 2019

Inborn Error of Cobalamin Metabolism Associated with the Intracellular Accumulation of Transcobalamin-Bound Cobalamin and Mutations in ZNF143, Which Codes for a Transcriptional Activator

scientific article published on 28 June 2016

Incorporating DNA shearing in standard affinity purification allows simultaneous identification of both soluble and chromatin-bound interaction partners

scientific article

Insulin regulation of protein translation repressor 4E-BP1, an eIF4E-binding protein, in renal epithelial cells.

scientific article

Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture

scientific article published on 19 January 2012

Journal Club: 35 years later, mRNA caps still matter

scientific article published on 01 November 2009

Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5

scientific article

Label-free quantitative proteomics trends for protein-protein interactions

scientific article

Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets

scientific article published on 11 November 2021

Lnk adaptor suppresses radiation resistance and radiation-induced B-cell malignancies by inhibiting IL-11 signaling

scientific article published on 02 December 2013

LuciPHOr: algorithm for phosphorylation site localization with false localization rate estimation using modified target-decoy approach

scientific article

MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.

scientific article published on 31 October 2017

MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway

scientific article

MSPLIT-DIA: sensitive peptide identification for data-independent acquisition

scientific article

Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition

scientific article

Mapping physical interactions within chromatin by proteomic approaches

scientific article published on May 2012

Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

scientific article published on 23 December 2019

Mass spectrometric tools for systematic analysis of protein phosphorylation

scientific article published on January 2012

Mass spectrometry approaches to study mammalian kinase and phosphatase associated proteins

scientific article published on 16 June 2012

Mechanistic insight into GPCR-mediated activation of the microtubule-associated RhoA exchange factor GEF-H1.

scientific article published on 11 September 2014

Molecular architecture of LSM14 interactions involved in the assembly of mRNA silencing complexes

scientific article published on 06 March 2018

Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry

scientific article

Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin

scientific article published on December 2016

Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission

scientific article

Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

scientific article

Novel NEDD1 phosphorylation sites regulate γ-tubulin binding and mitotic spindle assembly.

scientific article

OpenFreezer: a reagent information management software system

scientific article published on 28 July 2011

PP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpoint

scientific journal article

PP4 is a γH2AX phosphatase required for recovery from the DNA damage checkpoint.

scientific article published on 7 November 2008

PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4

scientific article

Palmitoylation targets the calcineurin phosphatase to the phosphatidylinositol 4-kinase complex at the plasma membrane

scientific article published on 18 October 2021

Parallel Exploration of Interaction Space by BioID and Affinity Purification Coupled to Mass Spectrometry

scientific article published in January 2017

Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients

scientific article published on 01 October 2020

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

scientific article published on 14 May 2020

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

scientific article published in November 2016

Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases

scientific article

Plk4 Promotes Cancer Invasion and Metastasis through Arp2/3 Complex Regulation of the Actin Cytoskeleton

scientific article published on 21 November 2016

Postnatal deamidation of 4E-BP2 in brain enhances its association with raptor and alters kinetics of excitatory synaptic transmission

scientific article

ProHits-viz: a suite of web tools for visualizing interaction proteomics data.

scientific article

ProHits: integrated software for mass spectrometry-based interaction proteomics

scientific article

Profiling the kinome: current capabilities and future challenges

scientific article published on 22 October 2012

Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.

scientific article published on 12 October 2016

Protein Complexes and Interaction Networks ⬇️

scientific article published on 01 May 2012

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions

scientific article

Protein phosphatase PP1/GLC7 interaction domain in yeast eIF2γ bypasses targeting subunit requirement for eIF2α dephosphorylation

scientific article published on 24 March 2014

Protein phosphatases, from molecules to networks.

scientific article published in December 2011

Proteome dynamics in health and disease. Foreword

scientific article published on 01 April 2015

Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion

scientific article published on 02 November 2019

Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7

scientific journal article

Proteomic analysis of the palmitoyl protein thioesterase 1 interactome in SH-SY5Y human neuroblastoma cells.

scientific article

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

scientific article published on 17 May 2018

Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity

scientific article

Proteomics approaches to decipher new signaling pathways

scientific article

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes

scientific article

Proximity dependent biotinylation: key enzymes and adaptation to proteomics approaches

scientific article published on 03 March 2020

Quantitative analysis of PPT1 interactome in human neuroblastoma cells.

scientific article published on 12 June 2015

Quantitative analysis of fitness and genetic interactions in yeast on a genome scale

scientific article

RNA chiropractics

scientific article published on 01 March 1998

Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling

scientific article published on 01 March 2020

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

scientific article

Regulation of CD133 by HDAC6 promotes β-catenin signaling to suppress cancer cell differentiation

scientific article published on 19 October 2012

Regulation of Protein Interactions by Mps One Binder (MOB1) Phosphorylation

scientific article

Regulation of translation initiation by FRAP/mTOR

scientific article (publication date: April 2001)

Regulatory Expansion in Mammals of Multivalent hnRNP Assemblies that Globally Control Alternative Splicing.

scientific article published in July 2017

Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC-MS/MS

scientific article published on 09 January 2020

Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation

scientific article

SAINT: probabilistic scoring of affinity purification-mass spectrometry data

scientific article

SAINTexpress: improvements and additional features in Significance Analysis of INTeractome software

scientific article

SAINTq: Scoring protein-protein interactions in affinity purification - mass spectrometry experiments with fragment or peptide intensity data.

scientific article

SETD6 controls the expression of estrogen-responsive genes and proliferation of breast carcinoma cells

scientific article

SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome

scientific article published on 7 July 2016

STK25 protein mediates TrkA and CCM2 protein-dependent death in pediatric tumor cells of neural origin

scientific article

Selective proteasomal degradation of the B'β subunit of protein phosphatase 2A by the E3 ubiquitin ligase adaptor Kelch-like 15

scientific article

Src homology 2 domain containing protein 5 (SH2D5) binds the breakpoint cluster region protein, BCR, and regulates levels of Rac1-GTP

scientific journal article

Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment

scholarly article by Shawn Xiong published in August 2018

Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein

scientific article

Structure-function analysis of core STRIPAK Proteins: a signaling complex implicated in Golgi polarization.

scientific article published on 11 May 2011

Subcellular proteomics

scientific article published on 29 April 2021

Systematic Examination of Antigen-Specific Recall T Cell Responses to SARS-CoV-2 versus Influenza Virus Reveals a Distinct Inflammatory Profile

scientific article published on 18 November 2020

Systematic exploration of essential yeast gene function with temperature-sensitive mutants

scientific article published on 27 March 2011

Systematic investigation of hierarchical phosphorylation by protein kinase CK2.

scientific article published on 5 November 2014

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions

scientific article published on 23 March 2020

Temporal regulation of EGF signalling networks by the scaffold protein Shc1

scientific article

The CRAPome: a contaminant repository for affinity purification-mass spectrometry data

scientific article

The GATOR-Rag GTPase pathway inhibits mTORC1 activation by lysosome-derived amino acids

scientific article

The Human Adenovirus Type 5 E4orf4 Protein Targets Two Phosphatase Regulators of the Hippo Signaling Pathway

scientific article

The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination

scientific article

The NEMP family supports metazoan fertility and nuclear envelope stiffness

scientific article published on 28 August 2020

The PPFIA1-PP2A protein complex promotes trafficking of Kif7 to the ciliary tip and Hedgehog signaling

scientific article published on 9 December 2014

The RNF146 and tankyrase pathway maintains the junctional Crumbs complex through regulation of angiomotin

scientific article

The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1

scientific article

The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation.

scientific article

The bromodomain-containing protein Ibd1 links multiple chromatin-related protein complexes to highly expressed genes in Tetrahymena thermophila.

scientific article published on 9 March 2018

The cargo receptor SURF4 promotes the efficient cellular secretion of PCSK9

scientific article published on 25 September 2018

The eIF4E-Binding Protein 4E-T Is a Component of the mRNA Decay Machinery that Bridges the 5' and 3' Termini of Target mRNAs

scientific article

The genetic landscape of a cell

scientific article

The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis

scientific article

The mRNA 5′ cap-binding protein eIF4E and control of cell growth ⬇️

scientific article published on April 1, 1998

The shieldin complex mediates 53BP1-dependent DNA repair

scientific article published in Nature

The target of rapamycin (TOR) proteins

scientific article published in June 2001

Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders

scientific article published on 31 August 2016

Translational control of ERK signaling through miRNA/4EHP-directed silencing

scientific article published on 7 February 2018

Translational control of cell fate: availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency

scientific article

Translational control of the antiapoptotic function of Ras.

scientific article

Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, β-glucocerebrosidase.

scientific article

Understudied proteins: opportunities and challenges for functional proteomics

scientific article published on 9 May 2022

Using ProHits to store, annotate, and analyze affinity purification-mass spectrometry (AP-MS) data

scientific article

Virtual Issue: Technological Innovations

scientific article published on 17 March 2020

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling

scientific article

Ydj1 governs fungal morphogenesis and stress response, and facilitates mitochondrial protein import via Mas1 and Mas2.

scientific article published on 2 October 2017

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

scientific article (publication date: 1999)

mapDIA: Preprocessing and statistical analysis of quantitative proteomics data from data independent acquisition mass spectrometry

scientific article

μ-Opioid Receptor Activates Signaling Pathways Implicated in Cell Survival and Translational Control ⬇️

scientific article published on September 4, 1998

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