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List of works by Eliezer Masliah

A Longitudinal Study of Behavioral Deficits in an AβPP Transgenic Mouse Model of Alzheimer's Disease

scientific article published on January 1, 2011

A blood-brain barrier (BBB) disrupter is also a potent α-synuclein (α-syn) aggregation inhibitor: a novel dual mechanism of mannitol for the treatment of Parkinson disease (PD)

scientific article

A brain-targeted, modified neurosin (kallikrein-6) reduces α-synuclein accumulation in a mouse model of multiple system atrophy

scientific article

A candidate gene study of intermediate histopathological phenotypes in HIV-associated neurocognitive disorders

scientific article published on 11 May 2020

A comparison of episodic memory deficits in neuropathologically-confirmed Dementia with Lewy bodies and Alzheimer's disease.

scientific article published in September 2004

A compendium of promoter-centered long-range chromatin interactions in the human genome

scientific article published on 09 September 2019

A comprehensive screening of copy number variability in dementia with Lewy bodies

scientific article published on 24 October 2018

A de novo compound targeting α-synuclein improves deficits in models of Parkinson's disease

scientific article published on 27 September 2016

A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration

scientific article

A neuropathologic diagnosis of Alzheimer's disease in an older adult with HIV-associated neurocognitive disorder

article

A neuropathological subset of Alzheimer's disease with concomitant Lewy body disease and spongiform change

scientific article published in January 1989

A neuroprotective brain-penetrating endopeptidase fusion protein ameliorates Alzheimer disease pathology and restores neurogenesis

scientific article

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

article by Sven J. van der Lee et al published 27 May 2019 in Acta Neuropathologica

A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation

scientific article published on December 5, 2012

A novel role for receptor-associated protein in somatostatin modulation: implications for Alzheimer's disease

scientific article

A novel triple repeat mutant tau transgenic model that mimics aspects of pick's disease and fronto-temporal tauopathies

scientific article

A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration.

scientific article

A polymorphism of the interleukin-1 beta gene at position +3953 influences progression and neuro-pathological hallmarks of Alzheimer's disease

scientific article published in September 2004

A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats

scientific article published in February 2013

A prospective longitudinal in vivo 1H MR spectroscopy study of the SIV/macaque model of neuroAIDS

scientific article

A protective role of the low density lipoprotein receptor-related protein against amyloid beta-protein toxicity

scientific article published on September 2000

A refined concept: Alpha synuclein dysregulation disease

scientific article published on 2 January 2018

A role for apoE in regulating the levels of alpha-1-antichymotrypsin in the aging mouse brain and in Alzheimer's disease

scientific article published on September 1999

A simple dot-immunobinding assay for quantification of synaptophysin-like immunoreactivity in human brain

scientific article published on February 1994

A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain

scientific article published on November 2, 2010

ANA Webinars: Clinical and basic research resilience during COVID-19

scientific article published on 15 December 2020

APOE DNA methylation is altered in Lewy body dementia

scientific article published on 12 March 2018

APOE ε4 increases risk for dementia in pure synucleinopathies

scientific article published on February 2013

APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis

scientific article

Aberrant Pax1 and Pax9 expression in Jarcho-Levin syndrome: report of two Caucasian siblings and literature review

scientific article (publication date: 15 July 2003)

Aberrant casein kinase II in Alzheimer's disease

scientific article published in January 1990

Aberrant presenilin-1 expression downregulates LDL receptor-related protein (LRP): is LRP central to Alzheimer's disease pathogenesis?

scientific article published on August 1999

Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease

scientific article published in January 2005

Abeta1-42 promotes cholinergic sprouting in patients with AD and Lewy body variant of AD.

scientific article published on July 2003

Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders

scientific article

Abnormal brain spectrin immunoreactivity in sprouting neurons in Alzheimer disease

scientific article

Abnormal distribution of the non-Abeta component of Alzheimer's disease amyloid precursor/alpha-synuclein in Lewy body disease as revealed by proteinase K and formic acid pretreatment

scientific article published on September 1, 1998

Abnormal glutamate transport function in mutant amyloid precursor protein transgenic mice

scientific article published on June 2000

Absence of elevated anti-alpha-synuclein and anti-EBV latent membrane protein antibodies in PD.

scientific article published in May 2002

Acardiac twin with externalized intestine adherent to placenta: unusual manifestation of omphalocele

scientific article

Accelerated epigenetic aging in brain is associated with pre-mortem HIV-associated neurocognitive disorders

scientific article published on 21 December 2015

Accounting for functional loss in Alzheimer's disease and dementia with Lewy bodies: Beyond cognition

scientific article published on July 11, 2013

Accumulation of amyloid precursor fragment in Alzheimer plaques

scientific article published on March 1, 1991

Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo

scientific article published on 24 March 2014

Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy

Acetylation of tau inhibits its degradation and contributes to tauopathy

scientific article

Activation of the amyloid cascade in apolipoprotein E4 transgenic mice induces lysosomal activation and neurodegeneration resulting in marked cognitive deficits

scientific article published on April 2008

Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy

scientific article published on 19 March 2015

Adiponectin Paradox as a Therapeutic Target in Alzheimer's Disease

scientific article published on 02 July 2020

Adiponectin Paradox in Alzheimer's Disease; Relevance to Amyloidogenic Evolvability?

scientific article published on 04 March 2020

Age at onset is associated with disease severity in Lewy body variant and Alzheimer's disease

scientific article published in October 2002

Age-appropriate cognition and subtle dopamine-independent motor deficits in aged tau knockout mice

scientific article published on 16 January 2013

Age-dependent molecular alterations in the autophagy pathway in HIVE patients and in a gp120 tg mouse model: reversal with beclin-1 gene transfer

scientific article published on January 24, 2013

Alcohol-induced brain changes in dogs

scientific article published in September 1991

Alpha-synuclein aggregation involves a bafilomycin A 1-sensitive autophagy pathway

scientific article

Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice.

scientific article published on April 2008

Alpha-synuclein deficient mice are resistant to toxin-induced multiple system atrophy

scientific article published on April 2010

Alpha-synuclein in Lewy body disease and Alzheimer's disease

scientific article

Alpha-synuclein overexpression in mice alters synaptic communication in the corticostriatal pathway

scientific article published on June 2010

Alpha-synuclein overexpression in oligodendrocytic cells results in impaired adhesion to fibronectin and cell death

scientific article

Alpha-synuclein sequesters Dnmt1 from the nucleus: a novel mechanism for epigenetic alterations in Lewy body diseases

scientific article

Alpha-synuclein up-regulates expression of caveolin-1 and down-regulates extracellular signal-regulated kinase activity in B103 neuroblastoma cells: role in the pathogenesis of Parkinson's disease

scientific article published on June 2003

Alterations in apolipoprotein E expression during aging and neurodegeneration

scientific article

Alterations in corticostriatal synaptic plasticity in mice overexpressing human alpha-synuclein

scientific article published on March 2009

Alterations in glutamate receptor 2/3 subunits and amyloid precursor protein expression during the course of Alzheimer's disease and Lewy body variant

scientific article published on December 1, 1997

Alterations in mGluR5 expression and signaling in Lewy body disease and in transgenic models of alpha-synucleinopathy--implications for excitotoxicity

scientific article

Alterations in the levels of vesicular trafficking proteins involved in HIV replication in the brains and CSF of patients with HIV-associated neurocognitive disorders

scientific article

Altered P-glycoprotein expression in AIDS patients with HIV encephalitis

scientific article published in October 2004

Altered expression of glutamate transporters under hypoxic conditions in vitro

scientific article published in April 2001

Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease

scientific article published in January 2001

Altered expression of the synuclein family mRNA in Lewy body and Alzheimer's disease

scientific article

Altered long-term potentiation in the hippocampus of apolipoprotein E-deficient mice

scientific article published on June 19, 1998

Altered p59Fyn kinase expression accompanies disease progression in Alzheimer's disease: implications for its functional role

scientific article published in May 2005

Altered presynaptic protein NACP is associated with plaque formation and neurodegeneration in Alzheimer's disease

scientific article published on January 1996

Altered protein tyrosine phosphorylation in Alzheimer's disease

scientific article published on 01 April 1991

Alternative splicing patterns of CYP2D genes in human brain and neurodegenerative disorders

scientific article published in October 1999

Alz-50 recognizes a phosphorylated epitope of tau protein

scientific article published on October 1, 1990

Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation

scientific article

Alzheimer disease without neocortical neurofibrillary tangles: "a second look".

scientific article published in April 2004

Alzheimer disease: AD pathology--emerging subtypes or age-of-onset spectrum?

scientific article published on 6 December 2011

Alzheimer's Disease: Recent Advances and Future Perspectives

scientific article published on January 1, 2013

Alzheimer's disease-like cerebrovascular pathology in transforming growth factor-beta 1 transgenic mice and functional metabolic correlates

scientific article published on April 2000

Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid

scientific article

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

scientific article

Amelioration of neurotoxic effects of HIV envelope protein gp120 by fibroblast growth factor: a strategy for neuroprotection

scientific article published in March 2001

Amelioration of the cerebrovascular amyloidosis in a transgenic model of Alzheimer's disease with the neurotrophic compound cerebrolysin

scientific article published on 7 July 2004

Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology.

scientific article

Amyloid beta protein toxicity mediated by the formation of amyloid-beta protein precursor complexes

scientific article published on December 2003

Amyloid precursor protein is localized in growing neurites of neonatal rat brain

scientific article published in October 1992

Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo.

scientific article published on May 1997

Amyloid protein precursor stimulates excitatory amino acid transport. Implications for roles in neuroprotection and pathogenesis

scientific article published in May 1998

Amyloid-beta peptide remnants in AN-1792-immunized Alzheimer's disease patients: a biochemical analysis

scientific article

Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease

scientific article

An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome

scientific article published on 29 March 2016

An antiaggregation gene therapy strategy for Lewy body disease utilizing beta-synuclein lentivirus in a transgenic model

scientific article published in December 2004

An antibody against phosphorylated neurofilaments identifies a subset of damaged association axons in Alzheimer's disease.

scientific article published on March 1993

An antiserum against amyloid beta-protein precursor detects a unique peptide in Alzheimer brain

scientific article published in May 1989

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.

scientific article

Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies

scientific article published on 29 January 2020

Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons

scientific article published on December 13, 2011

Anchorless prion protein results in infectious amyloid disease without clinical scrapie

scientific article

Antagonizing Neuronal Toll-like Receptor 2 Prevents Synucleinopathy by Activating Autophagy

scientific article published on 13 October 2015

Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy

scientific article published on 13 January 2017

Antibody-Aided Clearance of Extracellular α-Synuclein Prevents Cell-to-Cell Aggregate Transmission

scientific article published on September 26, 2012

Antidepressants reduce neuroinflammatory responses and astroglial alpha-synuclein accumulation in a transgenic mouse model of multiple system atrophy

scientific article

Antioxidant Sestrin-2 Redistribution to Neuronal Soma in Human Immunodeficiency Virus-Associated Neurocognitive Disorders

scientific article published on March 27, 2012

Antiretroviral therapy reduces neurodegeneration in HIV infection

scientific article

Apathy and APOE4 are associated with reduced BDNF levels in Alzheimer's disease

scientific article published on January 2014

ApoE4‐Driven Accumulation of Intraneuronal Oligomerized Aβ42 following Activation of the Amyloid Cascade In Vivo Is Mediated by a Gain of Function

scientific article published on February 15, 2011

Apoptotic signals within the basal forebrain cholinergic neurons in Alzheimer's disease

scientific article published on October 2005

Applications of ApoB LDLR-Binding Domain Approach for the Development of CNS-Penetrating Peptides for Alzheimer's Disease

scientific article published on January 2015

Appoptosin is a novel pro-apoptotic protein and mediates cell death in neurodegeneration

scientific article

Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis

scientific article

Assays for the Analysis of Synaptic Proteins in Neurodegenerative Disorders

scientific article published on January 1, 1999

Assessment of APOE in atypical parkinsonism syndromes

scientific article published on 21 February 2019

Association of CYP2D microsatellite polymorphism with Lewy body variant of Alzheimer's disease

scientific article published on June 1, 1998

Association of early experience with neurodegeneration in aged primates

scientific article

Association of monoamine oxidase A gene polymorphism with Alzheimer's disease and Lewy body variant

scientific article

Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory

scientific article

Astroglial activation of extracellular-regulated kinase in early stages of Alzheimer disease

scientific article

Astroglial expression of human alpha(1)-antichymotrypsin enhances alzheimer-like pathology in amyloid protein precursor transgenic mice

scientific article published in December 2000

Author Correction: Cellular senescence and Alzheimer disease: the egg and the chicken scenario

scientific article published on 13 August 2020

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Autophagy Is Increased in Postmortem Brains of Persons With HIV-1-Associated Encephalitis

scientific article published on June 1, 2011

Autophagy in Alzheimer's disease

scientific article published on January 2015

Autophagy in dementias

scientific article published on January 2012

Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype.

scientific article published on 4 December 2017

Autophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment

scientific article published in January 2014

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

scientific article published on February 2005

Axonopathy in an α-Synuclein Transgenic Model of Lewy Body Disease Is Associated with Extensive Accumulation of C-Terminal–Truncated α-Synuclein

scientific article published on January 9, 2013

Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss

scientific article

Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases

scientific article

Behavioral and neurophysiological effects of CNS expression of cytokines in transgenic mice

scientific article published on January 1996

Behavioral effects of dopaminergic agonists in transgenic mice overexpressing human wildtype alpha-synuclein

scientific article

Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology

scientific article

Beneficial effects of a neurotrophic peptidergic mixture persist for a prolonged period following treatment interruption in a transgenic model of Alzheimer's disease

scientific article published on 25 July 2011

Beta-amyloid immunotherapy prevents synaptic degeneration in a mouse model of Alzheimer's disease.

scientific article

Beta-synuclein displays an antiapoptotic p53-dependent phenotype and protects neurons from 6-hydroxydopamine-induced caspase 3 activation: cross-talk with alpha-synuclein and implication for Parkinson's disease

scientific article

Beta-synuclein regulates Akt activity in neuronal cells. A possible mechanism for neuroprotection in Parkinson's disease

scientific article

Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Abeta assembly forms throughout life

scientific article

Biochemical properties of highly neuroinvasive prion strains

scientific article

Biological transgenic mouse models of Alzheimer's disease

scientific article published on January 2008

Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration

scholarly article

Blood levels of alpha-1-antichymotrypsin and risk factors for Alzheimer's disease: effects of gender and apolipoprotein E genotype

scientific article published in January 2000

Bone marrow transplantation confers modest benefits in mouse models of Huntington's disease

scientific article published on January 2012

Brain creatine elevation and N‐acetylaspartate reduction indicates neuronal dysfunction in the setting of enhanced glial energy metabolism in a macaque model of NeuroAIDS

scientific article published on March 4, 2011

Brain deposition of beta-amyloid is a common pathologic feature in HIV positive patients

scientific article published on March 2005

Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology

scientific article

Bridging molecular genetics and biomarkers in lewy body and related disorders

scientific article

C-terminal alpha-synuclein immunoreactivity in structures other than Lewy bodies in neurodegenerative disorders

scientific article

CD8+ lymphocyte depletion without SIV infection does not produce metabolic changes or pathological abnormalities in the rhesus macaque brain

scientific article published on 4 April 2011

CNS findings in chronic fatigue syndrome and a neuropathological case report

scientific article published on 6 April 2017

Calpain-cleavage of alpha-synuclein: connecting proteolytic processing to disease-linked aggregation

scientific article published on May 2007

Can Alzheimer disease be prevented by amyloid-beta immunotherapy?

scientific article published on February 2010

Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice

scientific article

Cardiac death in a patient with adult-onset Still's disease treated with the interleukin 1 receptor inhibitor anakinra

scientific article published on 19 December 2006

Casein kinase II alteration precedes tau accumulation in tangle formation

scientific article published on February 1, 1992

Caspase cascades in human immunodeficiency virus-associated neurodegeneration.

scientific article published in May 2002

Caspase dependent DNA fragmentation might be associated with excitotoxicity in Alzheimer disease

scientific article published in November 1998

Cell type specificity of neurovascular coupling in cerebral cortex.

scientific article published on 31 May 2016

Cell-to-Cell Transmission of α-Synuclein Aggregates

scientific article published on January 1, 2012

Cell-to-cell transmission of non-prion protein aggregates.

scientific article published on 12 October 2010

Cellular internalization of alpha-synuclein aggregates by cell surface heparan sulfate depends on aggregate conformation and cell type

scientific article

Cellular neuropathology in HIV encephalitis.

scientific article published on January 1994

Cellular senescence and Alzheimer disease: the egg and the chicken scenario

scientific article published on 29 June 2020

Cellular source of apolipoprotein E4 determines neuronal susceptibility to excitotoxic injury in transgenic mice

scientific article

Central nervous system (CNS) transcriptomic correlates of human immunodeficiency virus (HIV) brain RNA load in HIV-infected individuals

scientific article published on 09 June 2021

Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice.

scientific article published on January 1994

Cerebral β-amyloid deposition predicts HIV-associated neurocognitive disorders in APOE ε4 carriers

scientific article published on November 2012

Cerebrolysin ameliorates performance deficits, and neuronal damage in apolipoprotein E-deficient mice.

scientific article published in February 1999

Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.

scientific article

Cerebrolysin modulates pronerve growth factor/nerve growth factor ratio and ameliorates the cholinergic deficit in a transgenic model of Alzheimer's disease

scientific article

Cerebrolysin™ efficacy in a transgenic model of tauopathy: role in regulation of mitochondrial structure

scientific article

Changes in pathological findings at autopsy in AIDS cases for the last 15 years

scientific article published on January 2000

Chaperone and anti-chaperone: two-faced synuclein as stimulator of synaptic evolution

scientific article published on October 2006

Characterization of the human alpha-synuclein gene: Genomic structure, transcription start site, promoter region and polymorphisms.

scientific article

Chemokine receptors and neurotrophic factors: potential therapy against aids dementia?

scientific article published on February 2008

Cholinergic deficits in the brains of patients with parkinsonism–dementia complex of Guam

scientific article published on December 21, 2001

Cholinergic dysfunction in diseases with Lewy bodies

scientific article published in January 2000

Chronic administration of the neurotrophic agent cerebrolysin ameliorates the behavioral and morphological changes induced by neonatal ventral hippocampus lesion in a rat model of schizophrenia

scientific article

Chronic cerebrolysin administration attenuates neuronal abnormalities in the basolateral amygdala induced by neonatal ventral hippocampus lesion in the rat.

scientific article

Chronic overproduction of transforming growth factor-beta1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice

scientific article published on January 2000

Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1.

scientific article published on 21 November 2016

Climbing the scaffolds of Parkinson's disease pathogenesis

scientific article

Clinical correlates of cortical and nucleus basalis pathology in Alzheimer dementia

scientific article

Clinical severity of Huntington's disease does not always correlate with neuropathologic stage

scientific article published on June 1, 2012

Clinical-neuropathological correlations in Alzheimer's disease and related dementias

scientific article published in September 1994

Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases

scientific article

Cognitive deficits and degeneration of interneurons in HIV+ methamphetamine users

scientific article published in October 2006

Cognitive deficits in a mouse model of pre‐manifest Parkinson’s disease

scientific article published on February 22, 2012

Combination of alpha-synuclein immunotherapy with anti-inflammatory treatment in a transgenic mouse model of multiple system atrophy

scientific article published on 05 January 2017

Combination therapies: The next logical Step for the treatment of synucleinopathies?

scientific article published on 21 September 2015

Combined Active Humoral and Cellular Immunization Approaches for the Treatment of Synucleinopathies

scientific article published on 15 December 2017

Combined exposure to Maneb and Paraquat alters transcriptional regulation of neurogenesis-related genes in mice models of Parkinson's disease

scientific article published on 28 September 2012

Commentary on "Synaptic Pathology in Prefrontal Cortex Is Present only with Severe Dementia in Alzheimer Disease" (JNEN 2001; 60;929-36).

scientific article published in March 2002

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

scientific article

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

scientific article

Comparison of Two Quantitative Methods for the Evaluation of Neuronal Number in the Frontal Cortex in Alzheimer Disease

scientific article published on November 1, 1997

Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

scientific article

Congenital nephrosis of the Finnish type: overview of placental pathology and literature review

scientific article

Congenital pulmonary airway malformation (congenital cystic adenomatoid malformation) with multiple extrapulmonary anomalies: autopsy report of a fetus at 19 weeks of gestation

scientific article published on 8 November 2004

Connecting Alzheimer's Disease With Diabetes Mellitus Through Amyloidogenic Evolvability

scientific article published on 28 October 2020

Correction to: A candidate gene study of intermediate histopathological phenotypes in HIV-associated neurocognitive disorders

scientific article published on 06 July 2020

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

scientific article published on 18 January 2020

Correction to: Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology

scientific article published on 04 August 2020

Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature

scientific article published on May 2012

Correlation of in vivo neuroimaging abnormalities with postmortem human immunodeficiency virus encephalitis and dendritic loss

scientific article published in March 2004

Correlation of major depressive disorder symptoms with FKBP5 but not FKBP4 expression in human immunodeficiency virus-infected individuals

scientific article published on October 2010

Correlation of nicotinic binding with neurochemical markers in Alzheimer's disease.

scientific article published in January 1998

Corrigendum to “Patterns of gene dysregulation in the frontal cortex of patients with HIV encephalitis”

article

Cortical Lewy body-containing neurons are pyramidal cells: laser confocal imaging of double-immunolabeled sections with anti-ubiquitin and SMI32.

scientific article published on January 1995

Cortical and subcortical neurodegeneration is associated with HIV neurocognitive impairment

scientific article published in April 2006

Cortical and subcortical patterns of synaptophysinlike immunoreactivity in Alzheimer's disease

scientific article published in January 1991

Cortical dendritic pathology in human immunodeficiency virus encephalitis

scientific article published on March 1, 1992

Corticotropin-releasing factor receptor-1 antagonism mitigates beta amyloid pathology and cognitive and synaptic deficits in a mouse model of Alzheimer's disease

scientific article

Could changing the course of Alzheimer's disease pathology with immunotherapy prevent dementia?

scientific article published on 01 July 2019

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

scientific article

Cross-Linking Cellular Prion Protein Triggers Neuronal Apoptosis in Vivo

scientific article published in Science

Cycles of aberrant synaptic sprouting and neurodegeneration in Alzheimer's and dementia with Lewy bodies

scientific article published on November 1, 2003

Cytokine receptor alterations during HIV infection in the human central nervous system

scientific article published on November 1994

DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers

scientific article published on March 2007

DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice

scientific article

Dale Schenk One Year Anniversary: Fighting to Preserve the Memories

scientific article published in January 2018

Damage and repair of DNA in HIV encephalitis

scientific article published on 01 November 2000

De novo prion aggregates trigger autophagy in skeletal muscle

scientific article published on 04 December 2013

Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition

scientific article published on 15 August 2010

Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson's disease.

scientific article

Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology

scientific article

Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice

scientific article

Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease

scientific article

Defining the Conformational Features of Anchorless, Poorly Neuroinvasive Prions

scientific article published on April 18, 2013

Degradation of proteins in the membrane-cytoskeleton complex in Alzheimer's disease. Might amyloidogenic APP processing be just the tip of the iceberg?

scientific article

Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease

scientific article

Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain

scientific article

Detection of borna disease virus antigen and RNA in human autopsy brain samples from neuropsychiatric patients

scientific article published in September 1996

Detection of peri-synaptic amyloid-β pyroglutamate aggregates in early stages of Alzheimer's disease and in AβPP transgenic mice using a novel monoclonal antibody

scientific article

Development of a new treatment for Alzheimer's disease and Parkinson's disease using anti-aggregatory beta-synuclein-derived peptides

scientific article

Development of new treatments for Parkinson's disease in transgenic animal models: a role for beta-synuclein

scientific article

Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium

scientific article

Differences in a dinucleotide repeat polymorphism in the tau gene between Caucasian and Japanese populations: implication for progressive supranuclear palsy

scientific article published in July 1998

Differential Effects of Pharmacologic and Genetic Modulation of NMDA Receptor Activity on HIV/gp120-Induced Neuronal Damage in an In Vivo Mouse Model

scientific article published on 15 September 2015

Differential Effects of UCHL1 Modulation on Alpha-Synuclein in PD-Like Models of Alpha-Synucleinopathy

scientific article published on April 13, 2012

Differential calcium alterations in animal models of neurodegenerative disease: Reversal by FK506

scientific article

Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy

scientific article published on 2 May 2017

Differential expression of immunophilins FKBP51 and FKBP52 in the frontal cortex of HIV-infected patients with major depressive disorder

scientific article

Differential expression of protein kinase C isozymes in rat glial cell cultures

scientific article published in May 1991

Differential involvement of protein kinase C isozymes in Alzheimer's disease

scientific article published in July 1990

Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters

scientific article

Differential neurotrophic effects of apolipoprotein E in aged transgenic mice

scientific article published on April 1999

Differential vulnerability of calbindin-immunoreactive neurons in HIV encephalitis

scientific article published on May 1995

Differing patterns of aberrant neuronal sprouting in Alzheimer's disease with and without Lewy bodies

scientific article

Diffuse plaques do not accentuate synapse loss in Alzheimer's disease

scientific article published on December 1990

Direct Membrane Association Drives Mitochondrial Fission by the Parkinson Disease-associated Protein α-Synuclein

scientific article published on April 13, 2011

Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies

scientific article

Disease-Modifying Effect of Adiponectin in Model of α-Synucleinopathies

scientific article

Disruption of copper homeostasis due to a mutation of Atp7a delays the onset of prion disease

scientific article

Distinct Pattern of Microgliosis in the Olfactory Bulb of Neurodegenerative Proteinopathies.

scientific article published on 19 March 2017

Distinct RolesIn Vivofor the Ubiquitin–Proteasome System and the Autophagy–Lysosomal Pathway in the Degradation of α-Synuclein

scientific article published on October 12, 2011

Distinct mechanisms of axonal globule formation in mice expressing human wild type α-synuclein or dementia with Lewy bodies-linked P123H ß-synuclein

scientific article published on September 26, 2012

Distinctive patterns of DNA methylation associated with Parkinson disease: identification of concordant epigenetic changes in brain and peripheral blood leukocytes

scientific article published on August 2013

Distribution of Brain HIV Load in AIDS

scientific article published on April 1, 1998

Distribution of obstructive intimal lesions and their cellular phenotypes in chronic pulmonary hypertension. A morphometric and immunohistochemical study

scientific article published in October 2000

Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model

scientific journal article

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

scientific article (publication date: 18 February 2000)

Doublecortin expression in CD8+ T-cells and microglia at sites of amyloid-β plaques: A potential role in shaping plaque pathology?

scientific article published on 6 April 2018

Dual effects of β-synuclein on the pathogenesis of Parkinson disease

scientific article published on 8 July 2013

Dual-therapy strategy for modification of adiponectin receptor signaling in aging-associated chronic diseases

scientific article published on 07 May 2018

Dynamics of alpha-synuclein aggregation and inhibition of pore-like oligomer development by beta-synuclein

scientific article published on April 2007

Dysregulation of signal transduction pathways as a potential mechanism of nervous system alterations in HIV-1 gp120 transgenic mice and humans with HIV-1 encephalitis

scientific article published on February 1996

E4 allele dosage does not predict cholinergic activity or synapse loss in Alzheimer's disease

scientific article published on January 2000

ER-associated degradation regulates Alzheimer's amyloid pathology and memory function by modulating γ-secretase activity

scientific article published on 13 November 2017

ESCRT-mediated uptake and degradation of brain-targeted α-synuclein single chain antibody attenuates neuronal degeneration in vivo

scientific article

Early BDNF treatment ameliorates cell loss in the entorhinal cortex of APP transgenic mice

scientific article published on September 2013

Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy

scientific article published on 23 December 2020

Early Visuospatial Deficits Predict the Occurrence of Visual Hallucinations in Autopsy-Confirmed Dementia With Lewy Bodies

scientific article published on September 1, 2012

Early and persistent alterations in prefrontal cortex MAO A and B in Alzheimer's disease

scientific article published in July 2003

Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein.

scientific article published in October 2004

Early and widespread cholinergic losses differentiate dementia with Lewy bodies from Alzheimer disease

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Early neuronal accumulation of DNA double strand breaks in Alzheimer's disease

scholarly article by Niraj M Shanbhag et al published 17 May 2019 in Acta neuropathologica communications

Early start of progressive motor deficits in Line 61 α-synuclein transgenic mice

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Effects of Cerebrolysin on amyloid-beta deposition in a transgenic model of Alzheimer's disease.

scientific article published in January 2002

Effects of Cerebrolysin on neurogenesis in an APP transgenic model of Alzheimer's disease

scientific article published on 28 November 2006

Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson's disease/dementia with Lewy bodies

scientific article published in Scientific Reports

Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease

scientific article published in June 2005

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

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Effects of single and combined immunotherapy approach targeting amyloid β protein and α-synuclein in a dementia with Lewy bodies-like model

scientific article published on 01 August 2019

Effects of the cholesterol-lowering compound methyl-beta-cyclodextrin in models of alpha-synucleinopathy

scientific article published on August 2006

Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies

scientific article published on 10 January 2022

Elevated S-adenosylhomocysteine in Alzheimer brain: influence on methyltransferases and cognitive function

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Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α‐synuclein

scientific article published on April 12, 2011

Empiric refinement of the pathologic assessment of Lewy-related pathology in the dementia patient

scientific article published on 29 January 2008

Enhanced dendritic spine number of neurons of the prefrontal cortex, hippocampus, and nucleus accumbens in old rats after chronic donepezil administration

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Enhanced lysosomal pathology caused by beta-synuclein mutants linked to dementia with Lewy bodies

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Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP.

scientific article published in April 2004

Entorhinal neurofibrillary tangles in Alzheimer disease with Lewy bodies

scientific article published on August 19, 1991

Environmental neurotoxic challenge of conditional alpha-synuclein transgenic mice predicts a dopaminergic olfactory-striatal interplay in early PD.

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Epigenetic alterations in the brain associated with HIV-1 infection and methamphetamine dependence

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Epstein-Barr virus-associated posttransplantation lymphoproliferative disorder following lung transplantation is more commonly of host origin

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Erratum to: Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain

scientific article published on 23 May 2016

Erythropoietin plus insulin-like growth factor-I protects against neuronal damage in a murine model of human immunodeficiency virus-associated neurocognitive disorders

scientific article published on September 2010

Escalating dose-multiple binge methamphetamine exposure results in degeneration of the neocortex and limbic system in the rat.

scientific article published on 6 June 2007

Evidence for Alteration of Gene Regulatory Networks through MicroRNAs of the HIV-infected brain: novel analysis of retrospective cases

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Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

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Evidence of oxidative stress in the brains of fetuses with CNS anomalies and islet cell hyperplasia

scientific article published on 15 July 2004

Evolvability and Neurodegenerative Disease: Antagonistic Pleiotropy Phenomena Derived from Amyloid Aggregates

Evolvability of Amyloidogenic Proteins in Human Brain

scientific article published in January 2018

Exacerbation of sensorimotor dysfunction in mice deficient in Atp13a2 and overexpressing human wildtype alpha-synuclein

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Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of Down syndrome

scientific article published in February 2009

Exposure to bacterial endotoxin generates a distinct strain of α-synuclein fibril

scientific article published on 04 August 2016

Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans

scientific article published on 06 October 2016

Expression Pattern of Synucleins (Non‐Aβ Component of Alzheimer's Disease Amyloid Precursor Protein/α‐Synuclein) During Murine Brain Development

scientific article published on July 1, 1998

Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice

scientific article published on March 2016

Expression of gp120 in mice evokes anxiety behavior: Co-occurrence with increased dendritic spines and brain-derived neurotrophic factor in the amygdala.

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Expression of mannose binding lectin in HIV-1-infected brain: implications for HIV-related neuronal damage and neuroAIDS

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Expression of stromal cell-derived factor 1alpha protein in HIV encephalitis

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Extensive HIV-1 intra-host recombination is common in tissues with abnormal histopathology

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FOXO4 is necessary for neural differentiation of human embryonic stem cells.

scientific article published on June 2013

Failure of prosencephalic unfolding and neuronal migration in acardia

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Fatal progressive hepatic necrosis associated with lamotrigine treatment: a case report and literature review

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Fatal pulmonary embolism update: 10 years of autopsy experience at an academic medical center

scientific article published on 30 July 2013

Fibroblast growth factor 1 regulates signaling via the glycogen synthase kinase-3beta pathway. Implications for neuroprotection

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Fibroblast growth factor modulates HIV coreceptor CXCR4 expression by neural cells. HNRC Group

scientific article published on March 2000

Fibroblast growth factors 1 and 2 in cerebrospinal fluid are associated with HIV disease, methamphetamine use, and neurocognitive functioning

scientific article published on 29 April 2016

Fluoxetine ameliorates behavioral and neuropathological deficits in a transgenic model mouse of α-synucleinopathy

scientific article published on 16 January 2012

Fluoxetine rescues impaired hippocampal neurogenesis in a transgenic A53T synuclein mouse model

scientific article published on January 2012

Following Activation of the Amyloid Cascade, Apolipoprotein E4 Drives the in vivo Oligomerization of Amyloid-β Resulting in Neurodegeneration

scientific article published on January 1, 2010

Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease

scientific article published on 6 April 2012

Fragmentation of the neuronal cytoskeleton in the Lewy body variant of Alzheimerʼs disease

scientific article published on March 7, 1995

Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease.

scientific article published in October 2005

Fyn kinase modulates synaptotoxicity, but not aberrant sprouting, in human amyloid precursor protein transgenic mice.

scientific article published in May 2004

GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology

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GDNF-expressing macrophages mitigate loss of dopamine neurons and improve Parkinsonian symptoms in MitoPark mice

scientific article published on 3 April 2018

GFAP reactivity, apolipoprotein E redistribution and cholesterol reduction in human astrocytes treated with alpha-synuclein

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Gene expression changes consistent with neuroAIDS and impaired working memory in HIV-1 transgenic rats.

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Gene expression patterns associated with neurological disease in human HIV infection

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Generation of reactive oxygen species and activation of NF-kappaB by non-Abeta component of Alzheimer's disease amyloid

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Genetic association of the low-density lipoprotein receptor-related protein gene (LRP), and apolipoprotein E receptor, with late-onset Alzheimer's disease

scientific article published on July 1, 1997

Genetic deletion of Nogo/Rtn4 ameliorates behavioral and neuropathological outcomes in amyloid precursor protein transgenic mice

scientific article published on 28 April 2010

Genetic evidence for the involvement of tau in progressive supranuclear palsy

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Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia

scientific article published on 01 January 2020

Genetic studies in Alzheimer's disease with an NACP/alpha-synuclein polymorphism

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Genetically altered transgenic models of Alzheimer's disease.

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Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

scientific article published on 15 February 2021

Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice

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Glial cells in Alzheimer's disease: preferential effect of APOE risk on scattered microglia.

scientific article published in January 1997

Glucocerebrosidase depletion enhances cell-to-cell transmission of α-synuclein

scientific article published on 26 August 2014

Glucocerebrosidase modulates cognitive and motor activities in murine models of Parkinson's disease.

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Glutamate Transporter Alterations in Alzheimer Disease Are Possibly Associated with Abnormal APP Expression

scientific article published on August 1, 1997

Glutamatergic axon-derived BDNF controls GABAergic synaptic differentiation in the cerebellum

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Glycogen synthase kinase 3 alteration in Alzheimer disease is related to neurofibrillary tangle formation

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Glycogen synthase kinase-3beta (GSK-3beta) inhibitors AR-A014418 and B6B3O prevent human immunodeficiency virus-mediated neurotoxicity in primary human neurons

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HIV Tat protein and amyloid-β peptide form multifibrillar structures that cause neurotoxicity.

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HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders

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HIV and Alzheimer's disease: complex interactions of HIV-Tat with amyloid β peptide and Tau protein

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HIV and antiretroviral therapy in the brain: neuronal injury and repair

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HIV mediates a productive infection of the brain

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HIV protease inhibitor exposure predicts cerebral small vessel disease

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HIV-1 Tat Activates Neuronal Ryanodine Receptors with Rapid Induction of the Unfolded Protein Response and Mitochondrial Hyperpolarization

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HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders

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Heritability and genetic variance of dementia with Lewy bodies

scientific article published on 03 April 2019

Herpes virus in Alzheimer's disease: relation to progression of the disease

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High beta-secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-beta levels: implications for the treatment of Alzheimer disease

scientific article published on 15 July 2005

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

scientific article (publication date: June 2000)

Hippocampal connectivity and Alzheimer's dementia: effects of synapse loss and tangle frequency in a two-component model

scientific article published in November 1994

Hippocampal grafts into the intact brain induce epileptic patterns.

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Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5--implications for dementia with Lewy bodies

scientific article published on 19 May 2014

Hippocampal sclerosis contributes to dementia in the elderly

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Hippocampal α-Synuclein in Dementia with Lewy Bodies Contributes to Memory Impairment and Is Consistent with Spread of Pathology

scientific article published on 30 December 2016

Hsp70 Reduces alpha-Synuclein Aggregation and Toxicity

scientific article published on 25 March 2004

Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits

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Human Wild-Type α-Synuclein Impairs Neurogenesis

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Human immunodeficiency virus-1/surface glycoprotein 120 induces apoptosis through RNA-activated protein kinase signaling in neurons.

scientific article published in October 2007

Human recombinant NACP/α-synuclein is aggregated and fibrillated in vitro: Relevance for Lewy body disease

scientific article published on July 20, 1998

Hyperactivation of signal transduction systems in Alzheimer's disease

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Hyperphosphorylated Tau in an α-synuclein-overexpressing transgenic model of Parkinson’s disease

scientific article published on April 1, 2011

Hypoestoxide reduces neuroinflammation and α-synuclein accumulation in a mouse model of Parkinson's disease

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Identification of the sites of tau hyperphosphorylation and activation of tau kinases in synucleinopathies and Alzheimer's diseases

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Identifying polyglutamine protein species in situ that best predict neurodegeneration

scientific article published on 30 October 2011

Immunoelectron microscopic study of synaptic pathology in Alzheimer's disease

scientific article published on January 1991

Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease

scientific article published in August 1989

Immunoreactivity of CD45, a protein phosphotyrosine phosphatase, in Alzheimer's disease

scientific article published on January 1, 1991

Immunoreactivity of the nuclear antigen p105 is associated with plaques and tangles in Alzheimer's disease.

scientific article

Immunotherapeutic Approaches Targeting Amyloid-β, α-Synuclein, and Tau for the Treatment of Neurodegenerative Disorders

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Immunotherapies for Aging-Related Neurodegenerative Diseases-Emerging Perspectives and New Targets

scientific article published on 28 April 2020

Immunotherapy for Alzheimer's disease: past, present and future

scientific article published on 10 June 2014

Immunotherapy for neurodegenerative diseases: Focus on α-synucleinopathies

scientific article published on 04 February 2013

Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation

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Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease

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Impaired Autophagy in APOE4 Astrocytes

scientific article published on 25 February 2016

Impaired Baroreflex Function in Mice Overexpressing Alpha-Synuclein

scientific article published on July 23, 2013

Impairment of Mitochondria in Adult Mouse Brain Overexpressing Predominantly Full-Length, N-Terminally Acetylated Human α-Synuclein

scientific article published on May 7, 2013

Importance of adiponectin activity in the pathogenesis of Alzheimer's disease

scientific article published on 11 July 2017

In vitro synaptotrophic effects of Cerebrolysin in NT2N cells.

scientific article published on May 1999

In vivo 1H MRS of brain injury and repair during acute SIV infection in the macaque model of neuroAIDS.

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In vivo alterations in calcium buffering capacity in transgenic mouse model of synucleinopathy

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In vivo demonstration that alpha-synuclein oligomers are toxic

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In vivo imaging of alpha-synuclein in mouse cortex demonstrates stable expression and differential subcellular compartment mobility

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In vivo stimulus-induced vasodilation occurs without IP3 receptor activation and may precede astrocytic calcium increase

scientific article published on May 2013

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

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Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor

scientific article published on August 1994

Increased BACE1 activity inhibits peripheral nerve regeneration after injury

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Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis

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Increased CDK5 Expression in HIV Encephalitis Contributes to Neurodegeneration via Tau Phosphorylation and Is Reversed with Roscovitine

scientific article published on April 1, 2011

Increased Vulnerability of the Hippocampus in Transgenic Mice Overexpressing APP and Triple Repeat Tau.

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Increased accumulation of intraneuronal amyloid beta in HIV-infected patients

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Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-beta 1

scientific article published on July 1995

Increased cortical expression of FK506 binding protein-51 in HIV-associated neurocognitive disorders

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Increased extracellular amyloid deposition and neurodegeneration in human amyloid precursor protein transgenic mice deficient in receptor-associated protein.

scientific article published in November 2002

Increased frequency of alpha-synuclein in the substantia nigra in human immunodeficiency virus infection

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Increased immunoreactivity of brain spectrin in Alzheimer disease: a marker for synapse loss?

scientific article published on October 1990

Increased level of DJ-1 in the cerebrospinal fluids of sporadic Parkinson's disease

scientific article published on 11 May 2006

Increased levels of α-1-antichymotrypsin in brains of patients with Alzheimer's disease correlate with activated astrocytes and are affected by APOE 4 genotype

scientific article published on August 1, 1998

Increased proteasome activity in human embryonic stem cells is regulated by PSMD11

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Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor

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Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson's disease

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Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model

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Insights into the pathogenesis of hydrocephalus from transgenic and experimental animal models

scientific article published in July 2004

Interaction between Abeta peptide and alpha synuclein: molecular mechanisms in overlapping pathology of Alzheimer's and Parkinson's in dementia with Lewy body disease

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Interactions between the amyloid precursor protein C-terminal domain and G proteins mediate calcium dysregulation and amyloid beta toxicity in Alzheimer's disease

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Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain

scientific article published in November 2003

Intracellular alpha-synuclein affects early maturation of primary oligodendrocyte progenitor cells

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Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

scientific article published on 16 December 2017

Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription

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Kindling-induced changes of protein kinase C levels in hippocampus and neocortex

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Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration

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LDL receptor-related protein (LRP) in Alzheimer's disease: towards a unified theory of pathogenesis

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LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation

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LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies

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Late onset dementia with argyrophilic grains and subcortical tangles or atypical progressive supranuclear palsy?

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Lenalidomide reduces microglial activation and behavioral deficits in a transgenic model of Parkinson's disease

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Lentivirus Mediated Delivery of Neurosin Promotes Clearance of Wild-type α-Synuclein and Reduces the Pathology in an α-Synuclein Model of LBD

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Lentivirus-expressed siRNA vectors against Alzheimer disease

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Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagy

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Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease

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Lewy bodies, Alzheimer pathology and APP mutation

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Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice

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Lifetime methamphetamine dependence is associated with cerebral microgliosis in HIV-1-infected adults

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Lithium ameliorates HIV-gp120-mediated neurotoxicity

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Lithium improves HIV-associated neurocognitive impairment

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Lobar atrophy with dense-core (brain stem type) Lewy bodies in a patient with dementia

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Localization of amyloid precursor protein in GAP43-immunoreactive aberrant sprouting neurites in Alzheimer's disease

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Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice

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Longitudinal live imaging of retinal α-synuclein::GFP deposits in a transgenic mouse model of Parkinson's Disease/Dementia with Lewy Bodies

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Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease

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Loss of TGF-beta 1 leads to increased neuronal cell death and microgliosis in mouse brain

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Loss of brain tau defines novel sporadic and familial tauopathies with frontotemporal dementia

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Lovastatin ameliorates alpha-synuclein accumulation and oxidation in transgenic mouse models of alpha-synucleinopathies

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Lysosomal pathology associated with alpha-synuclein accumulation in transgenic models using an eGFP fusion protein.

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MAPAS: a tool for predicting membrane-contacting protein surfaces

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MEF2C enhances dopaminergic neuron differentiation of human embryonic stem cells in a parkinsonian rat model

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Macrophage Activation Factors in the Brains of AIDS Patients

scientific article published in January 1996

Magnetic resonance spectroscopy reveals that activated monocytes contribute to neuronal injury in SIV neuroAIDS.

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Main portal vein access in transjugular intrahepatic portosystemic shunt procedures: use of three-dimensional ultrasound to ensure safety

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Many neuronal and behavioral impairments in transgenic mouse models of Alzheimer's disease are independent of caspase cleavage of the amyloid precursor protein

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Mapping the Subcellular Distribution of α-Synuclein in Neurons using Genetically Encoded Probes for Correlated Light and Electron Microscopy: Implications for Parkinson's Disease Pathogenesis

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Measurement of CNS HIV burden and its association with neurologic damage

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Mechanism of alpha-synuclein oligomerization and membrane interaction: theoretical approach to unstructured proteins studies

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Mechanisms of cell signaling and inflammation in Alzheimer's disease

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Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases

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Meta-analysis of synaptic pathology in Alzheimer's disease reveals selective molecular vesicular machinery vulnerability

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Methamphetamine stimulates interferon inducible genes in HIV infected brain

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MicroRNA-101 Modulates Autophagy and Oligodendroglial Alpha-Synuclein Accumulation in Multiple System Atrophy

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Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease

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Microvascular Injury in the Brains of Patients with Covid-19

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Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy

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Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.

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Modulation of aberrant CDK5 signaling rescues impaired neurogenesis in models of Alzheimer's disease.

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Modulation of the maladaptive stress response to manage diseases of protein folding

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Molecular and pathologic insights from latent HIV-1 infection in the human brain

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Molecular determinants of α-synuclein mutants' oligomerization and membrane interactions

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Molecular mechanisms of neurodegeneration in Alzheimer's disease

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Molecular pathology of neuro-AIDS (CNS-HIV).

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Motor and Nonmotor Symptoms of Parkinson’s Disease: Antagonistic Pleiotropy Phenomena Derived from α-Synuclein Evolvability?

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MultiTEP platform-based DNA vaccines for alpha-synucleinopathies: preclinical evaluation of immunogenicity and therapeutic potency

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Multilevel analysis of neuropathogenesis of neurocognitive impairment in HIV.

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Multiple non-cell autonomous actions of alpha-synuclein in neurodegenerative diseases: Is there a direct link?

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Multiple system atrophy: a clinical and neuropathological perspective

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Multiple system atrophy: experimental models and reality

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Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux

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Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis

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Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

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Mutant three-repeat tau expression initiates retinal ganglion cell death through Caspase-2

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NACP, a Synaptic Protein Involved in Alzheimer's Disease, Is Differentially Regulated during Megakaryocyte Differentiation

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NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration

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National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

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National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach

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Neocortical damage during HIV infection

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Neocortical lewy body counts correlate with dementia in the Lewy body variant of Alzheimer's disease.

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Neocortical pathology in chronic murine retroviral encephalitis

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Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.

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Neprilysin regulates amyloid Beta peptide levels

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Neprilysin-2 is an important β-amyloid degrading enzyme

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Nerve Growth Factor Gene Therapy: Activation of Neuronal Responses in Alzheimer Disease

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Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain

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Neural Stem Cells Rescue Cognitive and Motor Dysfunction in a Transgenic Model of Dementia with Lewy Bodies through a BDNF-Dependent Mechanism

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Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models

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Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer's disease model

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Neuro-peptide treatment with Cerebrolysin improves the survival of neural stem cell grafts in an APP transgenic model of Alzheimer disease

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NeuroAIDS, drug abuse, and inflammation: building collaborative research activities

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Neurobiology of HIV.

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Neurochemical markers do not correlate with cognitive decline in the Lewy body variant of Alzheimer disease

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Neurodegeneration and cognitive impairment in apoE-deficient mice is ameliorated by infusion of recombinant apoE.

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Neurodegeneration in a transgenic mouse model of multiple system atrophy is associated with altered expression of oligodendroglial-derived neurotrophic factors

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Neurodegeneration in the central nervous system of apoE-deficient mice

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Neurodegeneration of somatostatin-immunoreactive neurons in HIV encephalitis

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Neurodegeneration: Aggregates feel the strain.

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Neurodegenerative Alzheimer-like pathology in PDAPP 717V-->F transgenic mice

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Neurofibrillary and neurodegenerative pathology in APP-transgenic mice injected with AAV2-mutant TAU: neuroprotective effects of Cerebrolysin

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Neurofibrillary pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein

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Neurofibrillary tangles in the dentate granule cells of patients with Alzheimer's disease, Lewy body disease and progressive supranuclear palsy

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Neurogranin binds α-synuclein in the human superior temporal cortex and interaction is decreased in Parkinson's disease

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Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models

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Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6

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Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy.

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Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia

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Neuronal to oligodendroglial alpha-synuclein redistribution in a double transgenic model of multiple system atrophy

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Neuropathologic confirmation of definitional criteria for human immunodeficiency virus-associated neurocognitive disorders

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Neuropathology of dementia with Lewy bodies in advanced age: A comparison with Alzheimer disease

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Neuropathology: Alzheimer's in real time

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Neuropeptide Treatment with Cerebrolysin Enhances the Survival of Grafted Neural Stem Cell in an α-Synuclein Transgenic Model of Parkinson's Disease

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Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease

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Neuroprotective effects of Cerebrolysin in triple repeat Tau transgenic model of Pick's disease and fronto-temporal tauopathies

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Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

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Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation.

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Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders

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Neuroprotective effects of the immunomodulatory drug FK506 in a model of HIV1-gp120 neurotoxicity

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Neuropsychiatric Features of Frontal Lobe Dysfunction in Autopsy-Confirmed Patients with Lewy Bodies and “Pure” Alzheimer Disease

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Neuropsychological deficits associated with diffuse Lewy body disease

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Neurotoxic effects of apolipoprotein E4 are mediated via dysregulation of calcium homeostasis

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Neurotoxic effects of the HCV core protein are mediated by sustained activation of ERK via TLR2 signaling

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Neurotransmitters in basal ganglia and cortex of Alzheimer's disease with and without Lewy bodies

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Neurotrophic and neuroprotective effects of hAPP in transgenic mice

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Neurotrophic effects of Cerebrolysin in the Mecp2(308/Y) transgenic model of Rett syndrome

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Neurovirological correlation with HIV-associated neurocognitive disorders and encephalitis in a HAART-era cohort

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Next-generation active immunization approach for synucleinopathies: implications for Parkinson's disease clinical trials

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NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models

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NitroSynapsin for the treatment of neurological manifestations of tuberous sclerosis complex in a rodent model

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NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism

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Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

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Non-A.beta. Component of Alzheimer's Disease Amyloid (NAC) is Amyloidogenic

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Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2

scientific article published on 08 June 2016

Noncanonical transnitrosylation network contributes to synapse loss in Alzheimer's disease

scientific article published on 03 December 2020

Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions

scientific article published on 18 November 2019

Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation

scientific article published on 10 June 2017

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

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Novel role of human CD4 molecule identified in neurodegeneration

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Novel strategies for Alzheimer's disease treatment

scientific article published on December 2007

Novel therapeutic strategy for neurodegeneration by blocking Aβ seeding mediated aggregation in models of Alzheimer's disease

scientific article

OTK18 expression in brain mononuclear phagocytes parallels the severity of HIV-1 encephalitis

scientific article published in May 2004

Olfactory deficits in mice overexpressing human wildtype alpha-synuclein

scientific article

Oligodendroglial α-synucleinopathy-driven neuroinflammation in multiple system atrophy

scientific article published on 31 January 2019

Oligomer-prone E57K-mutant alpha-synuclein exacerbates integration deficit of adult hippocampal newborn neurons in transgenic mice

scientific article

Oral N-Acetyl-Cysteine Attenuates Loss of Dopaminergic Terminals in α-Synuclein Overexpressing Mice

scientific article published on August 23, 2010

Overexpression of CYP2D6 attenuates the toxicity of MPP+ in actively dividing and differentiated PC12 cells

scientific article published in January 2003

Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice

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Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation

scientific article published on May 19, 2011

Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro

scientific article published on March 1999

P1-203 Inhibition of the TGF-beta signaling pathway results in increased neurodegeneration and amyloid deposition in human APP transgenic mice

PART, a distinct tauopathy, different from classical sporadic Alzheimer disease

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PDGF is associated with neuronal and glial alterations of Alzheimer's disease

scientific article published in July 1995

PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function.

scientific article

PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically

scientific article published on 7 December 2015

PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis

scientific article published in December 2017

Parkinson disease mutant E46K enhances α-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo

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Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on α-synuclein

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Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease

scientific article (publication date: 29 April 2011)

Pathogenesis of age-related HIV neurodegeneration

scientific article published on 21 February 2019

Pathogenesis of hepatitis C virus coinfection in the brains of patients infected with HIV.

scientific article published on 15 June 2007

Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease

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Patterns of aberrant sprouting in Alzheimer's disease

scientific article published in May 1991

Patterns of gene dysregulation in the frontal cortex of patients with HIV encephalitis

scientific article published in December 2004

Patterns of neurodegeneration in HIV encephalitis

scientific article published on January 1996

Patterns of selective neuronal damage in methamphetamine-user AIDS patients

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Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension

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Peptides of presenilin-1 bind the amyloid precursor protein ectodomain and offer a novel and specific therapeutic approach to reduce ß-amyloid in Alzheimer's disease

scientific article

Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo.

scientific article published on 9 January 2017

Peripheral Delivery of a CNS Targeted, Metalo-Protease Reduces Aβ Toxicity in a Mouse Model of Alzheimer's Disease

scientific article published on January 31, 2011

Perspective on the calcium dyshomeostasis hypothesis in the pathogenesis of selective neuronal degeneration in animal models of Alzheimer's disease

scientific article published on 24 January 2017

Perturbed neurogenesis in the adult hippocampus associated with presenilin-1 A246E mutation

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Phorbol ester-induced neuritic alterations in the rat neocortex. Structural and immunocytochemical studies

scientific article published in October 1993

Phospholipase Cɛ links G protein-coupled receptor activation to inflammatory astrocytic responses

scientific article published on February 11, 2013

Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions

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Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders

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Phosphorylation of synucleins by members of the Polo-like kinase family

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Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

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Placenta accreta in a separate uterine horn.

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Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

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Plaque-only Alzheimer disease is usually the lewy body variant, and vice versa.

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Plasma levels of DJ-1 as a possible marker for progression of sporadic Parkinson's disease

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Plasma soluble CD163 is associated with postmortem brain pathology in human immunodeficiency virus infection

scientific article published on 27 February 2017

Polyamine pathway contributes to the pathogenesis of Parkinson disease

scientific article published on September 13, 2010

Possible Involvement of Adiponectin, the Anti-Diabetes Molecule, in the Pathogenesis of Alzheimer's Disease

scientific article published on 8 April 2016

Possible Role of Amyloid Cross-Seeding in Evolvability and Neurodegenerative Disease

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Possible Role of the Polyglutamine Elongation in Evolution of Amyloid-Related Evolvability

Potential for cell therapy in Parkinson's disease using genetically programmed human embryonic stem cell-derived neural progenitor cells

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Preclinical Assessment of Young Blood Plasma for Alzheimer Disease.

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Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo

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Prediction of conversion from mild cognitive impairment to dementia with neuronally derived blood exosome protein profile

scientific article published on 07 May 2016

Presenilin Binding Protein Is Associated with Neurofibrillary Alterations in Alzheimer’s Disease and Stimulates Tau Phosphorylation

scientific article published on November 1, 2001

Preserved functional autonomic phenotype in adult mice overexpressing moderate levels of human alpha-synuclein in oligodendrocytes

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Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine

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Preventive immunization of aged and juvenile non-human primates to β-amyloid

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Primary age-related tauopathy (PART): a common pathology associated with human aging

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Prion infection promotes extensive accumulation of α-synuclein in aged human α-synuclein transgenic mice

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Prion-induced amyloid heart disease with high blood infectivity in transgenic mice

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Prodegenerative IκBα expression in oligodendroglial α-synuclein models of multiple system atrophy

scientific article published on 17 December 2013

Profound increase in sensitivity to glutamatergic- but not cholinergic agonist-induced seizures in transgenic mice with astrocyte production of IL-6.

scientific article published in July 2003

Progressive accumulation of amyloid-beta oligomers in Alzheimer's disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins

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Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain

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Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice

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Prostaglandin E2 Induced Polymerization of Human α-1-Antichymotrypsin and Suppressed Its Protease Inhibitory Activity: Implications for Alzheimer's Disease

scientific article published on August 10, 1998

Protection against HIV-1 gp120-induced brain damage by neuronal expression of human amyloid precursor protein

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Protection from cyanide-induced brain injury by the Nrf2 transcriptional activator carnosic acid

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Protective role of endogenous gangliosides for lysosomal pathology in a cellular model of synucleinopathies

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Protein Kinases and Growth Associated Proteins in Plaque Formation in Alzheimer's Disease

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Protein aggregate spreading in neurodegenerative diseases: problems and perspectives

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Protein kinase C alteration is an early biochemical marker in Alzheimer's disease

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Protein kinases and phosphorylation in neurologic disorders and cell death

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Protein profiling of isolated uterine AA amyloidosis causing fetal death in goats

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Proteomic analysis of highly prevalent amyloid A amyloidosis endemic to endangered island foxes

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Proton magnetic resonance spectroscopy reveals neuroprotection by oral minocycline in a nonhuman primate model of accelerated NeuroAIDS

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Quantitative immunohistochemistry of synaptophysin in human neocortex: an alternative method to estimate density of presynaptic terminals in paraffin sections

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Quantitative neuropathologic correlates of changes in ratio of N-acetylaspartate to creatine in macaque brain

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Quantitative relationships between huntingtin levels, polyglutamine length, inclusion body formation, and neuronal death provide novel insight into huntington's disease molecular pathogenesis

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Quantitative synaptic alterations in the human neocortex during normal aging

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Rapid Fragmentation of Vimentin in Human Skin Fibroblasts Exposed to Tamoxifen: A Possible Involvement of Caspase-3

scientific article published on June 18, 1998

Rapidly progressive dementia in a patient with the Lewy body variant of Alzheimer's disease

scientific article published on August 1, 1991

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

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Rarity of the Alzheimer disease-protective APP A673T variant in the United States

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Re-evaluation of the structural organization of neuritic plaques in Alzheimer's disease.

scientific article published on November 1993

Reactive synaptogenesis assessed by synaptophysin immunoreactivity is associated with GAP-43 in the dentate gyrus of the adult rat

scientific article published on August 1, 1991

Recent advances in the development of immunotherapies for tauopathies

scientific article published on October 21, 2010

Recognition memory span in autopsy-confirmed Dementia with Lewy Bodies and Alzheimer's Disease

scientific article published on 13 July 2015

Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting.

scientific article published on 13 December 2017

Reduced IGF-1 signaling delays age-associated proteotoxicity in mice

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Reduced hypocretin (orexin) levels in dementia with Lewy bodies

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Reduced neuritic outgrowth and cell adhesion in neuronal cells transfected with human alpha-synuclein

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Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models

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Reducing Endogenous α-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer's Disease Transgenic Mouse Model

scientific article published on July 2016

Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice.

scientific article published in May 2006

Reduction of neurological damage by a peptide segment of the amyloid beta/A4 protein precursor in a rabbit spinal cord ischemia model

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Region-specific tauopathy and synucleinopathy in brain of the alpha-synuclein overexpressing mouse model of Parkinson's disease

scientific article published on August 3, 2011

Regional Comparison of the Neurogenic Effects of CNTF-Derived Peptides and Cerebrolysin in AβPP Transgenic Mice

scientific article published on January 1, 2011

Regionally-specific microglial activation in young mice over-expressing human wildtype alpha-synuclein

scientific article published on 27 June 2012

Regulation of amyloid precursor protein processing by the Beclin 1 complex

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Regulation of synaptic structure by ubiquitin C-terminal hydrolase L1.

scientific article published on June 2009

Relationship of antiretroviral treatment to postmortem brain tissue viral load in human immunodeficiency virus-infected patients

scientific article published in April 2006

Relationships between astrogliosis and 1H MR spectroscopic measures of brain choline/creatine and myo-inositol/creatine in a primate model.

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Remembering Robert D. Terry at a Time of Change in the World of Alzheimer's Disease

scientific article published on 01 January 2019

Remembering in Alzheimer's disease: the "Bobs" at the turn of the new century

scientific article published in July 2005

Reversible ischemia increases levels of Alzheimer amyloid protein precursor without increasing levels of mRNA in the rabbit spinal cord

scientific article published on October 3, 1997

Rifampicin reduces alpha-synuclein in a transgenic mouse model of multiple system atrophy

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Role of Alterations in Protein Kinase p38γ in the Pathogenesis of the Synaptic Pathology in Dementia With Lewy Bodies and α-Synuclein Transgenic Models

scientific article published on 31 March 2020

Role of Protein Aggregation in Mitochondrial Dysfunction and Neurodegeneration in Alzheimer's and Parkinson's Diseases

scientific article published on January 1, 2003

Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E.

scientific article published in July 2001

Role of cytochrome c as a stimulator of alpha-synuclein aggregation in Lewy body disease

scientific article published on October 1999

Role of neurotrophic factor alterations in the neurodegenerative process in HIV associated neurocognitive disorders

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Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons

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Role of synucleins in Alzheimer's disease

scientific article published on 24 June 2009

Role of trophic factors on neuroimmunity in neurodegenerative infectious diseases

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Role of tuberin in neuronal degeneration

scientific article published on 5 March 2008

Role of α-synuclein in adult neurogenesis and neuronal maturation in the dentate gyrus

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Role of α‐synuclein penetration into the membrane in the mechanisms of oligomer pore formation

scientific article published on February 27, 2012

S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease

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S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson's disease

scientific journal article

S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration

scientific article (publication date: 25 May 2006)

SCG10, a neuron-specific growth-associated protein in Alzheimer's disease

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SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.

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SORLA attenuates EphA4 signaling and amyloid β-induced neurodegeneration

scientific article published on 7 November 2017

Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy

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Selective neuronal vulnerability in HIV encephalitis

scientific article published on November 1, 1992

Selective targeting of 3 repeat Tau with brain penetrating single chain antibodies for the treatment of neurodegenerative disorders

scientific article published on 14 June 2018

Septin 3 gene polymorphism in Alzheimer's disease.

scientific article published in January 2004

Serine 421 regulates mutant huntingtin toxicity and clearance in mice.

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Serotonergic dysfunction in the A53T alpha-synuclein mouse model of Parkinson's disease

scientific article published on 23 July 2015

Severe Alveolar Proteinosis Following Chemotherapy for Acute Myeloid Leukemia in a Lung Allograft Recipient

scientific article published on October 1, 2001

Severe, demyelinating leukoencephalopathy in AIDS patients on antiretroviral therapy

scientific article published on May 2002

Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC α-synuclein transgenic rat model of Parkinson's disease

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Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120

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Silencing of murine transthyretin and retinol binding protein genes has distinct and shared behavioral and neuropathologic effects

scientific article published on 21 June 2014

Sirenomelia of an intracytoplasmic sperm injection conceptus: a case report and review of mechanism

scientific article published on May 2006

Small molecule NPT-440-1 inhibits ionic flux through Aβ1-42 pores: Implications for Alzheimer's disease therapeutics

scientific article published on 19 June 2016

Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells

scientific article published on 3 December 2013

Social Cognition Impairments in Mice Overexpressing Alpha-Synuclein Under the Thy1 Promoter, a Model of Pre-manifest Parkinson's Disease

scientific article published on 13 January 2015

Spectrum of human immunodeficiency virus-associated neocortical damage

scientific article published on September 1, 1992

Spongiform Change in Dementia With Lewy Bodies and Alzheimer Disease

scientific article published on April 1, 2013

Statins reduce neuronal alpha-synuclein aggregation in in vitro models of Parkinson's disease

scientific article published on 28 January 2008

Structural diversity of Alzheimer's disease amyloid-β dimers and their role in oligomerization and fibril formation.

scientific article published on January 2014

Suppression of α-synuclein toxicity and vesicle trafficking defects by phosphorylation at S129 in yeast depends on genetic context

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Synapse alterations in the hippocampal-entorhinal formation in Alzheimer's disease with and without Lewy body disease.

scientific article published in December 1994

Synaptic activity becomes excitotoxic in neurons exposed to elevated levels of platelet-activating factor

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Synaptic alterations in apolipoprotein E knockout mice

scientific article published on January 1999

Synaptic and dendritic pathology in murine retroviral encephalitis

scientific article published on December 1993

Synaptic and neuritic alterations during the progression of Alzheimer's disease

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Synaptic loss in cognitively impaired aged rats is ameliorated by chronic human nerve growth factor infusion

scientific article published in September 1995

Synaptic pathology in Borna disease virus persistent infection.

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Synaptic remodeling during aging and in Alzheimer's disease.

scientific article published on January 2006

Synaptic structural abnormalities in the Ts65Dn mouse model of Down Syndrome.

scientific article published in December 2004

Synaptotagmin and synaptic transmission alterations in apolipoprotein E-deficient mice

scientific article published on April 1999

Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice

scientific article published on 01 December 1994

Synergistic Increase of Serum BDNF in Alzheimer Patients Treated with Cerebrolysin and Donepezil: Association with Cognitive Improvement in ApoE4 Cases

scientific article published on 07 April 2016

Synuclein impairs trafficking and signaling of BDNF in a mouse model of Parkinson's disease

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Systemic Central Nervous System (CNS)-targeted Delivery of Neuropeptide Y (NPY) Reduces Neurodegeneration and Increases Neural Precursor Cell Proliferation in a Mouse Model of Alzheimer Disease

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Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy body disease

scientific article published on 05 March 2019

T-complex protein 1-ring complex enhances retrograde axonal transport by modulating tau phosphorylation

scientific article published on 12 September 2018

TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

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TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions

scientific article published on 19 January 2014

TOM40 Mediates Mitochondrial Dysfunction Induced by α-Synuclein Accumulation in Parkinson’s Disease

scientific article published on April 23, 2013

Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model

scientific article published on 28 August 2005

Targeting Microglial and Neuronal Toll-like Receptor 2 in Synucleinopathies

scientific article published on 01 October 2019

Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease

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Temporal/compartmental changes in viral RNA and neuronal injury in a primate model of NeuroAIDS.

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Thalamic nuclei in Alzheimer disease: evidence against the cholinergic hypothesis of plaque formation

scientific article published on July 1989

The Amazon rain forest plant Uncaria tomentosa (cat's claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles

scientific article published in Scientific Reports

The CYP2D6B allele is associated with a milder synaptic pathology in Alzheimer's disease

scientific article published in October 1995

The CYP2D6B mutant allele is overrepresented in the Lewy body variant of Alzheimer's disease

scientific article published in January 1995

The HIV Protein gp120 Alters Mitochondrial Dynamics in Neurons

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The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies

scientific article published on 18 February 2020

The Lewy body variant of Alzheimer's disease: a clinical and pathologic entity

scientific article published on January 1990

The National NeuroAIDS Tissue Consortium brain gene array: two types of HIV-associated neurocognitive impairment

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The North American Multiple System Atrophy Study Group

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The Role of alpha-synuclein assembly and metabolism in the pathogenesis of Lewy body disease

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The anticancer drug sunitinib promotes autophagyand protects from neurotoxicity in an HIV-1 Tat model of neurodegeneration

scientific article published on 19 January 2017

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice

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The biochemical aftermath of anti-amyloid immunotherapy

scientific article published on October 7, 2010

The cannabinoid CB₂ receptor agonist AM1241 enhances neurogenesis in GFAP/Gp120 transgenic mice displaying deficits in neurogenesis

scientific article published on January 2014

The challenge of connecting the dots in the B.R.A.I.N.

scientific article published on October 2013

The decline in synapses and cholinergic activity is asynchronous in Alzheimer's disease

scientific article published in November 2000

The emerging role of infectious pathogens in neurodegenerative diseases

scientific article published on December 2003

The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer's disease

scientific article published on 02 September 2020

The many faces of α-synuclein: from structure and toxicity to therapeutic target

scientific article published on January 1, 2013

The neuropathology of multiple system atrophy and its therapeutic implications.

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The neuroprotective effects of Cerebrolysin in a transgenic model of Alzheimer's disease are associated with improved behavioral performance.

scientific article published in November 2003

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

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The relationship of quantitative brain magnetic resonance imaging measures to neuropathologic indexes of human immunodeficiency virus infection

scientific article published in November 1994

The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements

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The role of NAC in amyloidogenesis in Alzheimer's disease

scientific article published on February 2000

The role of mitochondrial alterations in the combined toxic effects of human immunodeficiency virus Tat protein and methamphetamine on calbindin positive-neurons.

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The shifting patterns of HIV encephalitis neuropathology

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The small molecule alpha-synuclein misfolding inhibitor, NPT200-11, produces multiple benefits in an animal model of Parkinson's disease

scientific article published in Scientific Reports

The synaptic organization of the neocortex in Alzheimer's disease

scientific article published on October 1993

The synaptic protein NACP is abnormally expressed during the progression of Alzheimer's disease

scientific article published in May 1996

The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice

scientific article published on 11 May 2015

The utility of SELENBP1 gene expression as a biomarker for major psychotic disorders: replication in schizophrenia and extension to bipolar disorder with psychosis

scientific article published on September 2008

Therapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer's disease models

scientific article (publication date: December 2016)

Therapeutic approaches in Parkinson's disease and related disorders

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Three-dimensional analysis of the relationship between synaptic pathology and neuropil threads in Alzheimer disease.

scientific article published in July 1992

Time course and progression of wild type α-synuclein accumulation in a transgenic mouse model

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Toll-like receptor 4 promotes α-synuclein clearance and survival of nigral dopaminergic neurons

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Toll-like receptor pathway gene expression is associated with human immunodeficiency virus-associated neurodegeneration

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Topographical distribution of synaptic-associated proteins in the neuritic plaques of Alzheimer's disease hippocampus.

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Toward a unified therapeutics approach targeting putative amyloid-β oligomer receptors

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Transgenerational Interaction of Alzheimer's Disease with Schizophrenia through Amyloid Evolvability

scholarly article by Yoshiki Takamatsu et al published 2019 in Journal of Alzheimer's Disease

Transgenic animal models of neurodegenerative diseases and their application to treatment development

scientific article published on 17 August 2007

Transgenic models of alpha-synuclein pathology: past, present, and future

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Transgenic models to assess the neuropathogenic potential of HIV-1 proteins and cytokines.

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Transglutaminase 2 exacerbates α-synuclein toxicity in mice and yeast

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Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network

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Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity

scholarly article

Type 1 diabetes exaggerates features of Alzheimer's disease in APP transgenic mice

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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

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Umbilical cord stricture in a 21-week fetus.

scientific article published in January 2004

Understanding Creutzfeldt-Jackob disease from a viewpoint of amyloidogenic evolvability

scientific article published on 01 December 2020

Upregulation of the E3 ligase NEDD4-1 by Oxidative Stress Degrades IGF-1 Receptor Protein in Neurodegeneration

scientific article published on August 8, 2012

Variants associated with Gaucher disease in multiple system atrophy

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Viral persistence in neurons alters synaptic plasticity and cognitive functions without destruction of brain cells

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Visuospatial deficits predict rate of cognitive decline in autopsy-verified dementia with Lewy bodies

scientific article published on November 2008

Vitamin E supplementation prevents spatial learning deficits and dendritic alterations in aged apolipoprotein E-deficient mice

scientific article published in December 2000

Whole transcriptome sequencing enables discovery and analysis of viruses in archived primary central nervous system lymphomas

scientific article published on 4 September 2013

Widespread changes in dendritic and axonal morphology in Mecp2-mutant mouse models of Rett syndrome: evidence for disruption of neuronal networks

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Widespread microRNA dysregulation in multiple system atrophy - disease-related alteration in miR-96.

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alpha-1-Antichymotrypsin polymorphism in the gene promoter region affects survival and synapsis loss in Alzheimer's disease

scientific article published in January 2004

alpha-Synuclein aggregates interfere with Parkin solubility and distribution: role in the pathogenesis of Parkinson disease

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alpha-Synuclein is phosphorylated in synucleinopathy lesions

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alpha-synuclein promotes mitochondrial deficit and oxidative stress

scientific article published on August 2000

beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor

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beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

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c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease

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nNOS Expressing Neurons in the Entorhinal Cortex and Hippocampus Are Affected in Patients with Alzheimer's Disease

scientific article published on March 1, 1998

p75 reduces beta-amyloid-induced sympathetic innervation deficits in an Alzheimer's disease mouse model

scholarly article

α-Synuclein Protects against Oxidative Stress via Inactivation of the c-Jun N-terminal Kinase Stress-signaling Pathway in Neuronal Cells

scientific article published on January 14, 2002

α-Synuclein impairs oligodendrocyte progenitor maturation in multiple system atrophy

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α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer

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α-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1.

scientific article

α-Synuclein interferes with the ESCRT-III complex contributing to the pathogenesis of Lewy body disease

scientific article published on 5 January 2016

α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies

article published in the Proceedings of the National Academy of Sciences of the United States of America

α-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy

scientific article published on 08 April 2016

α-synuclein conformational antibodies fused to penetratin are effective in models of Lewy body disease

scientific article published on 16 June 2016