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List of works by Alessandro Sette

17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells

scientific article

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016

scientific article published oln 16 November 2016

4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination

scientific article published on 01 March 2000

A CD8+ T cell heptaepitope minigene vaccine induces protective immunity against Chlamydia pneumoniae

scientific article published on May 2005

A Case of Human Lassa Virus Infection With Robust Acute T-Cell Activation and Long-Term Virus-Specific T-Cell Responses

scientific article published on June 2017

A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood.

scientific article published on 24 June 2016

A Modified Injector and Sample Acquisition Protocol Can Improve Data Quality and Reduce Inter-Instrument Variability of the Helios Mass Cytometer

scientific article published on 30 July 2019

A Protective Role for Dengue Virus-Specific CD8+ T Cells

scientific article (publication date: 15 April 2009)

A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans

scientific article

A Review on T Cell Epitopes Identified Using Prediction and Cell-Mediated Immune Models for Mycobacterium tuberculosis and Bordetella pertussis

scientific article published on 29 November 2018

A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2

scientific article published on 16 March 2020

A Structure-Based Algorithm to Predict Potential Binding Peptides to MHC Molecules with Hydrophobic Binding Pockets ⬇️

scientific article published on November 1, 1997

A behind the scenes tour of the IEDB curation process: an optimized process empirically integrating automation and human curation efforts

scientific article published on 02 July 2020

A community resource benchmarking predictions of peptide binding to MHC-I molecules

scientific article published on 9 June 2006

A comparison of epitope repertoires associated with myasthenia gravis in humans and nonhuman hosts

scientific article

A computational pipeline to generate MHC binding motifs.

scientific article

A computational resource for the prediction of peptide binding to Indian rhesus macaque MHC class I molecules

scientific article published on 18 August 2005

A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus

scientific article

A decaepitope polypeptide primes for multiple CD8+ IFN-gamma and Th lymphocyte responses: evaluation of multiepitope polypeptides as a mode for vaccine delivery

scientific article published on 01 June 2002

A detailed analysis of the murine TAP transporter substrate specificity

scientific article

A disease-related epitope of Torpedo acetylcholine receptor. Residues involved in I-Ab binding, self-nonself discrimination, and TCR antagonism

scientific article published on 01 May 1994

A large fraction of HLA class I ligands are proteasome-generated spliced peptides.

scientific article published on 20 October 2016

A meta-analysis of the existing knowledge of immunoreactivity against hepatitis C virus (HCV)

scientific article

A microcomputer program for probit analysis of interleukin-2 (IL-2) titration data

scientific article

A molecular view of multiple sclerosis and experimental autoimmune encephalitis: what can we learn from the epitope data?

scientific article

A multivalent and cross-protective vaccine strategy against arenaviruses associated with human disease

scientific article

A multivalent vaccination strategy for the prevention of Old World arenavirus infection in humans

scientific article

A novel approach to the generation of high affinity class II-binding peptides

scientific article published on 01 September 1990

A pilot study of the CY-1899 T-cell vaccine in subjects chronically infected with hepatitis B virus. The CY1899 T Cell Vaccine Study Group

scientific article published in August 1999

A population response analysis approach to assign class II HLA-epitope restrictions

scientific article

A quantitative analysis of the variables affecting the repertoire of T cell specificities recognized after vaccinia virus infection

scientific article

A rational strategy to design multiepitope immunogens based on multiple Th lymphocyte epitopes

scientific article published in June 2002

A roadmap for the immunomics of category A-C pathogens

scientific article

A shared MHC supertype motif emerges by convergent evolution in macaques and mice, but is totally absent in human MHC molecules

scientific article

A side-by-side comparison of T cell reactivity to fifty-nine Mycobacterium tuberculosis antigens in diverse populations from five continents

scientific article

A single minor histocompatibility antigen encoded by UGT2B17 and presented by human leukocyte antigen-A*2902 and -B*4403

scientific article published on 01 May 2007

A strategy to determine HLA class II restriction broadly covering the DR, DP, and DQ allelic variants most commonly expressed in the general population

scientific article published on 8 February 2013

A structured model for immune exposures

scientific article published on 01 January 2020

A subdominant CD8(+) cytotoxic T lymphocyte (CTL) epitope from the Plasmodium yoelii circumsporozoite protein induces CTLs that eliminate infected hepatocytes from culture

scientific article

A survey of known immune epitopes in the enteroviruses strains associated with acute flaccid myelitis

scientific article published on 23 August 2019

A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach

scientific article

AIDS virus specific CD8+ T lymphocytes against an immunodominant cryptic epitope select for viral escape

scientific article

Ab and T cell epitopes of influenza A virus, knowledge and opportunities

scholarly article

Adaptive immunity to SARS-CoV-2 and COVID-19

scientific article

Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii

scientific article published on 22 September 2016

Allergen and Epitope Targets of Mouse-Specific T Cell Responses in Allergy and Asthma

scientific article published on 13 February 2018

Allergen content in German cockroach extracts and sensitization profiles to a new expanded set of cockroach allergens determine in vitro extract potency for IgE reactivity

scientific article published on 28 August 2018

Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells

scientific article published on 12 May 2017

Allergy-associated T cell epitope repertoires are surprisingly diverse and include non-IgE reactive antigens

scientific article

Altered helper T lymphocyte function associated with chronic hepatitis B virus infection and its role in response to therapeutic vaccination in humans.

scientific article published in March 1999

Altered ligands reveal limited plasticity in the T cell response to a pathogenic epitope

scientific article

Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo

scientific article published on April 1995

An Integrated Workflow To Assess Technical and Biological Variability of Cell Population Frequencies in Human Peripheral Blood by Flow Cytometry

scientific article published on 9 January 2017

An analysis of the epitope knowledge related to Mycobacteria

scientific article

An effective CTL peptide vaccine for Ebola Zaire Based on Survivors' CD8+ targeting of a particular nucleocapsid protein epitope with potential implications for COVID-19 vaccine design

scientific article published on 28 April 2020

An in silico-in vitro Pipeline Identifying an HLA-A*02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients

scientific article published on 15 November 2019

An ontology for immune epitopes: application to the design of a broad scope database of immune reactivities

scientific article

An ontology for major histocompatibility restriction

scientific article

An open-source computational and data resource to analyze digital maps of immunopeptidomes

scientific article

Analysis of HLA A*02 association with vaccine efficacy in the RV144 HIV-1 vaccine trial

scientific article

Analysis of Human RSV Immunity at the Molecular Level: Learning from the Past and Present

scientific article

Analysis of MHC-specific peptide motifs. Applications in immunotherapy.

scientific article published on January 1995

Analysis of T cell responses to the major allergens from German cockroach: epitope specificity and relationship to IgE production

scientific article

Analysis of cytotoxic T cell responses to dominant and subdominant epitopes during acute and chronic lymphocytic choriomeningitis virus infection

scientific article published in December 1996

Analysis of epitope information related to Bacillus anthracis and Clostridium botulinum

scientific article published in February 2008

Analysis of lysozyme-specific immune responses by synthetic peptides. I. Characterization of antibody and T cell-mediated responses to the N-terminal peptide of hen egg-white lysozyme

scientific article published on 01 January 1986

Analysis of the binding of gluten T-cell epitopes to various human leukocyte antigen class II molecules

scientific article

Anti-HIV potency of T-cell responses elicited by dendritic cell therapeutic vaccination

scientific article published on 09 September 2019

Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis

scientific article published on June 2017

Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor ⬇️

scientific article published on February 21, 1992

Antigen analogs as therapeutic agents

scientific article published on January 1995

Antigen analogs as tools to study T-cell activation function and activation

scientific article

Antigen analogs/MHC complexes as specific T cell receptor antagonists

scientific article published on January 1994

Antigen analogues as antagonists of the T cell receptor.

scientific article published in March 1993

Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity

scientific article published on 16 September 2020

Antigen-specific acquired immunity in human brucellosis: implications for diagnosis, prognosis, and vaccine development

scientific article

Antigens for CD4 and CD8 T cells in tuberculosis

scientific article published on 22 May 2014

Apoptotic Epitope-Specific CD8+ T Cells and Interferon Signaling Intersect in Chronic Hepatitis C Virus Infection

scientific article published on 19 September 2015

Applications for T-cell epitope queries and tools in the Immune Epitope Database and Analysis Resource ⬇️

scientific article published on October 31, 2010

Association between specific timothy grass antigens and changes in TH1- and TH2-cell responses following specific immunotherapy

scientific article

Association of HLA-DRB1–restricted CD4+ T cell responses with HIV immune control ⬇️

scientific article published on June 23, 2013

Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes

scientific article

Atheroprotective Vaccination with MHC-II Restricted Peptides from ApoB-100.

scientific article published on 27 December 2013

Atheroprotective vaccination with MHC-II-restricted ApoB peptides induces peritoneal IL-10-producing CD4 T cells

scientific article published on 13 January 2017

Author Correction: Pre-existing immunity to SARS-CoV-2: the knowns and unknowns

scientific article published on 17 August 2020

Autoantigen recognition by human CD8 T cell clones: enhanced agonist response induced by altered peptide ligands ⬇️

scientific article published on November 15, 1997

Autoimmunity in Parkinson's Disease: The Role of α-Synuclein-Specific T Cells

scholarly article by Francesca Garretti et al published 25 February 2019 in Frontiers in Immunology

Autologous peptides constitutively occupy the antigen binding site on Ia.

scientific article

Automated benchmarking of peptide-MHC class I binding predictions

scientific article published on 25 February 2015

Automated generation and evaluation of specific MHC binding predictive tools: ARB matrix applications

scientific article published on 3 May 2005

Automatic Generation of Validated Specific Epitope Sets

scientific article

Automating document classification for the Immune Epitope Database

scientific article

Autoreactive T cells can be protected from tolerance induction through competition by flanking determinants for access to class II MHC.

scientific article

Autoreactive cytotoxic T lymphocytes in human immunodeficiency virus type 1-infected subjects

scientific article

Benchmark datasets of immune receptor-epitope structural complexes

scientific article published on 10 October 2019

Benchmarking predictions of MHC class I restricted T cell epitopes in a comprehensively studied model system

scientific article published on 26 May 2020

Better living through ontologies at the Immune Epitope Database

scientific article

Beyond HLA-A*0201: New HLA-Transgenic Nonobese Diabetic Mouse Models of Type 1 Diabetes Identify the Insulin C-Peptide as a Rich Source of CD8+ T Cell Epitopes ⬇️

scientific article published on April 25, 2012

Binding of a peptide antigen to multiple HLA alleles allows definition of an A2-like supertype

scientific article published on January 1995

Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II.

scientific article

Binding of myelin basic protein peptides to human histocompatibility leukocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patients ⬇️

scientific article published on February 1, 1993

Biologic significance and therapeutic implications of antigen/MHC interactions

scientific article published in November 1989

Bispecificity for myelin and neuronal self-antigens is a common feature of CD4 T cells in C57BL/6 mice

scientific article published on 18 August 2014

Bolstering the Number and Function of HSV-1-Specific CD8+ Effector Memory T Cells and Tissue-Resident Memory T Cells in Latently Infected Trigeminal Ganglia Reduces Recurrent Ocular Herpes Infection and Disease.

scientific article published on 24 May 2017

Broad and cross-clade CD4+ T-cell responses elicited by a DNA vaccine encoding highly conserved and promiscuous HIV-1 M-group consensus peptides

scientific article

Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes

scientific article

Broadly reactive human CD8 T cells that recognize an epitope conserved between VZV, HSV and EBV.

scientific article

Brucella melitensis T cell epitope recognition in humans with brucellosis in Peru

scientific article published on 14 October 2013

CD4 T cells specific for a latency-associated γ-herpesvirus epitope are polyfunctional and cytotoxic

scientific article published on 5 November 2014

CD4+ T cells are not required for the induction of dengue virus-specific CD8+ T cell or antibody responses but contribute to protection after vaccination

scientific article

CD4+T‐cell inhibitory ligands: a tool for characterizing dysfunctional CD4+ T cells during chronic infection ⬇️

scientific article published on September 1, 2013

CD8 + T-Cell Epitope Mapping for Pneumonia Virus of Mice in H-2 b Mice ⬇️

scientific article published on July 3, 2013

CD8+ T Cells Specific to Apoptosis-Associated Antigens Predict the Response to Tumor Necrosis Factor Inhibitor Therapy in Rheumatoid Arthritis

scientific article published on 10 June 2015

CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation

scientific article published on 14 November 2007

CD8+ T-Cell responses to Trypanosoma cruzi are highly focused on strain-variant trans-sialidase epitopes

scientific article

COVID-19 and possible links with Parkinson's disease and parkinsonism: from bench to bedside

scientific article published on 20 August 2020

Candidate Targets for Immune Responses to 2019-Novel Coronavirus (nCoV): Sequence Homology- and Bioinformatic-Based Predictions

scientific article published on 25 February 2020

Candidate targets for immune responses to 2019-Novel Coronavirus (nCoV): sequence homology- and bioinformatic-based predictions

scientific article

Capacity of intact proteins to bind to MHC class II molecules

scientific article published on 01 August 1989

Case Report: Convalescent Plasma, a Targeted Therapy for Patients with CVID and Severe COVID-19

scientific article published on 20 November 2020

Celiac disease association with CD8+ T cell responses: identification of a novel gliadin-derived HLA-A2-restricted epitope.

scientific article

Cell-mediated immunological responses in cervical and vaginal cancer patients immunized with a lipidated epitope of human papillomavirus type 16 E7 ⬇️

scientific article published on September 1, 1998

Cellular immune response to cryptic epitopes during therapeutic gene transfer

scholarly article

Cellular immune responses to the hepatitis B virus polymerase

scientific article published in November 2004

Cellular immune selection with hepatitis C virus persistence in humans

scientific article

Changing immunodominance patterns in antiviral CD8 T-cell responses after loss of epitope presentation or chronic antigenic stimulation ⬇️

scientific article published on October 10, 2003

Characterization and epitope identification of the T cell response in non-allergic individuals exposed to mouse allergen

Characterization of MHC- and TCR-binding residues of the myelin oligodendrocyte glycoprotein 38-51 peptide

scientific article published in January 2004

Characterization of Magnitude and Antigen Specificity of HLA-DP, DQ, and DRB3/4/5 Restricted DENV-Specific CD4+ T Cell Responses

Characterization of Proinsulin T Cell Epitopes Restricted by Type 1 Diabetes-Associated HLA Class II Molecules

scientific article published on 30 March 2020

Characterization of a naturally processed MHC class II-restricted T-cell determinant of hen egg lysozyme

scientific article

Characterization of the T-cell epitope that causes anti-GBM glomerulonephritis

scientific article

Characterization of the peptide binding motif of a rhesus MHC class I molecule (Mamu-A*01) that binds an immunodominant CTL epitope from simian immunodeficiency virus ⬇️

scientific article published on June 15, 1998

Characterization of the peptide binding specificity of the HLA class I alleles B*38:01 and B*39:06.

scientific article

Characterization of the peptide-binding specificity of Mamu-A*11 results in the identification of SIV-derived epitopes and interspecies cross-reactivity

scientific article

Characterization of the peptide-binding specificity of Mamu-B*17 and identification of Mamu-B*17-restricted epitopes derived from simian immunodeficiency virus proteins

scientific article

Characterization of the specificity of peptide binding to four DR haplotypes

scientific article published on September 1990

Characterizing monkeypox virus specific CD8+ T cell epitopes in rhesus macaques

scientific article published on 28 September 2013

Chronic lymphocytic choriomeningitis virus infection actively down-regulates CD4+ T cell responses directed against a broad range of epitopes

scientific article published on July 2007

Circulating T cell-monocyte complexes are markers of immune perturbations.

scientific article

Citrullination only infrequently impacts peptide binding to HLA class II MHC

scientific article

Class I MHC-peptide interaction: structural and functional aspects.

scientific article published on July 1994

Class I MHC-peptide interactions: structural requirements and functional implications

scientific article published on January 1995

Class I molecules with similar peptide-binding specificities are the result of both common ancestry and convergent evolution

scientific article published on 14 February 2003

Classification of A1- and A24-supertype molecules by analysis of their MHC-peptide binding repertoires

scientific article published on 8 July 2005

Classification of the Universe of Immune Epitope Literature: Representation and Knowledge Gaps

scientific article

Comparison of HLA ligand elution data and binding predictions reveals varying prediction performance for the multiple motifs recognized by HLA-DQ2.5.

scientific article published on 16 October 2020

Comparison of cytotoxic T lymphocyte responses induced by peptide or DNA immunization: implications on immunogenicity and immunodominance

scientific article published on 01 March 1997

Comparison of structural requirements for interaction of the same peptide with I-Ek and I-Ed molecules in the activation of MHC class II-restricted T cells ⬇️

scientific article published on July 1, 1991

Complementary mutations in an antigenic peptide allow for crossreactivity of autoreactive T-cell clones

scientific article published on December 1996

Comprehensive Review of Human -Specific CD8+ T Cell Epitopes

article

Comprehensive analysis of T cell epitope discovery strategies using 17DD yellow fever virus structural proteins and BALB/c (H2d) mice model

scientific article (publication date: 15 August 2008)

Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases

scientific article published on 09 December 2020

Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases

scientific article

Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells

scientific article published on 11 April 2013

Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides

scientific article published on May 2004

Comprehensive immunological evaluation reveals surprisingly few differences between elite controller and progressor Mamu-B*17-positive simian immunodeficiency virus-infected rhesus macaques

scientific article published on 2 April 2008

Computerized data analysis in cellular immunology. Enhancement and suppression of immune responses

scientific article

Consequences of periodic α-to-β(3) residue replacement for immunological recognition of peptide epitopes

scientific article

Conservancy of mAb Epitopes in Ebolavirus Glycoproteins of Previous and 2014 Outbreaks

scientific article published on 3 November 2014

Conserved hierarchy of helper T cell responses in a chimpanzee during primary and secondary hepatitis C virus infections

scientific article published on January 2004

Constitutive presentation of dominant epitopes from endogenous naturally processed self-beta 2-microglobulin to class II-restricted T cells leads to self-tolerance

scientific article published on 01 January 1995

Correction: Definition of Human Epitopes Recognized in Tetanus Toxoid and Development of an Assay Strategy to Detect Ex Vivo Tetanus CD4+ T Cell Responses.

scientific article published on 20 February 2018

Correction: Preventing tumor escape by targeting a post-proteasomal trimming independent epitope

scientific article published on 17 January 2017

Correction: Quantitative and Qualitative Perturbations of CD8+ MAITs in Healthy Mycobacterium tuberculosis-Infected Individuals

scientific article published on 22 July 2020

Correction: Unexpected Diversity of Cellular Immune Responses against Nef and Vif in HIV-1-Infected Patients Who Spontaneously Control Viral Replication

scientific article published in PLoS ONE

Correlates of protection efficacy induced by vaccinia virus-specific CD8+ T-cell epitopes in the murine intranasal challenge model

scientific article published on March 2009

Cost sensitive hierarchical document classification to triage PubMed abstracts for manual curation

scientific article

Counter-regulation of regulatory T cells by autoreactive CD8+ T cells in rheumatoid arthritis

scientific article published on 16 February 2019

Coverage of related pathogenic species by multivalent and cross-protective vaccine design: arenaviruses as a model system

scientific article

Cross-presentation of caspase-cleaved apoptotic self antigens in HIV infection

scientific article published on 18 November 2007

Cross-reactive memory T cells and herd immunity to SARS-CoV-2

scientific article published on 06 October 2020

Curation of complex, context-dependent immunological data

scientific article

Current Understanding of the Role of T Cells in Chikungunya, Dengue and Zika Infections

scientific article published in 2022

Cutting Edge: Transcriptional Profiling Reveals Multifunctional and Cytotoxic Antiviral Responses of Zika Virus-Specific CD8 T Cells

article

Cutting edge: Prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells

scientific article published on 14 June 2013

Cutting edge: murine cytomegalovirus induces a polyfunctional CD4 T cell response

scientific article published on May 2008

Cutting edge: the conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1*0401 MHC class II molecule

scientific article published in July 2003

Cytomegalovirus-Specific CD4 T Cells Are Cytolytic and Mediate Vaccine Protection

scientific article

Cytotoxic CD4 T Cells: Differentiation, Function, and Application to Dengue Virus Infection

scientific article

DAFi: A Directed Recursive Filtering and Clustering Approach to Data-Driven Identification of Cell Populations from Polychromatic Flow Cytometry Data

DAFi: A directed recursive data filtering and clustering approach for improving and interpreting data clustering identification of cell populations from polychromatic flow cytometry data

scientific article published on 17 April 2018

DRB1*0301 molecules recognize a structural motif distinct from the one recognized by most DR beta 1 alleles ⬇️

scientific article published on October 15, 1992

Dataset size and composition impact the reliability of performance benchmarks for peptide-MHC binding predictions

scientific article

Deciphering the MHC-associated peptidome: a review of naturally processed ligand data

scientific article

Deciphering the human antigenome

scientific article

Defining the herpes simplex virus-specific CD8+ T cell repertoire in C57BL/6 mice

scientific article published on 25 February 2011

Defining the risk of SARS-CoV-2 variants on immune protection

scientific article published on 31 March 2022

Definition of CD4 Immunosignatures Associated with MTB.

scientific article published on 24 March 2014

Definition of Human Epitopes Recognized in Tetanus Toxoid and Development of an Assay Strategy to Detect Ex Vivo Tetanus CD4+ T Cell Responses

scientific article

Definition of a DQ3.1-specific binding motif.

scientific article published on May 1994

Definition of an HLA-A3-like supermotif demonstrates the overlapping peptide-binding repertoires of common HLA molecules

scientific article published on February 1996

Definition of epitopes and antigens recognized by vaccinia specific immune responses: their conservation in variola virus sequences, and use as a model system to study complex pathogens

scientific article

Definition of specific peptide motifs for four major HLA-A alleles

scientific article published on 01 April 1994

Definition of the Mamu A*01 peptide binding specificity: application to the identification of wild-type and optimized ligands from simian immunodeficiency virus regulatory proteins

scientific article

Degenerate Cytotoxic T Cell Epitopes from P. falciparum Restricted by Multiple HLA-A and HLA-B Supertype Alleles ⬇️

scientific article published on July 1, 1997

Degenerate and promiscuous recognition by CTL of peptides presented by the MHC class I A3-like superfamily: implications for vaccine development ⬇️

scientific article published on August 15, 1997

Dendritic cells generated in vivo by a chimeric hematopoietic growth factor, progenipoietin-4, demonstrate potent immunological function

scientific article

Dengue virus infection elicits highly polarized CX3CR1+ cytotoxic CD4+ T cells associated with protective immunity

scientific article published on 20 July 2015

Dengue-specific CD8+ T cell subsets display specialized transcriptomic and TCR profiles

scientific article published on 18 March 2019

Derivation of HLA-A11/Kb transgenic mice: functional CTL repertoire and recognition of human A11-restricted CTL epitopes ⬇️

scientific article published on November 15, 1997

Derivation of HLA-B*0702 transgenic mice: functional CTL repertoire and recognition of human B*0702-restricted CTL epitopes

scientific article published on February 2003

Derivation of an amino acid similarity matrix for peptide: MHC binding and its application as a Bayesian prior

scientific article

Design and preclinical development of a recombinant protein and DNA plasmid mixed format vaccine to deliver HIV-derived T-lymphocyte epitopes

scientific article published on 26 September 2009

Design and testing of peptide-based cytotoxic T-cell-mediated immunotherapeutics to treat infectious diseases and cancer.

scientific article published on January 1995

Design and utilization of epitope-based databases and predictive tools

scientific article

Design of multi-epitope, analogue-based cancer vaccines

scientific article

Detailed characterization of the peptide binding specificity of five common Patr class I MHC molecules

scientific article published on 22 June 2006

Detection of EXP1-Specific CD4+ T Cell Responses Directed Against a Broad Range of Epitopes Including Two Promiscuous MHC Class II Binders During Acute Plasmodium falciparum Malaria

scientific article published on 01 January 2019

Detection of a broad range of low level MHC class II-restricted Hepatitis Delta Virus (HDV)-specific T cell responses regardless of the clinical status

article

Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection ⬇️

scientific article

Determinants of T cell reactivity to the Mycobacterium leprae GroES homologue.

scientific article published in July 1997

Determination of a Predictive Cleavage Motif for Eluted Major Histocompatibility Complex Class II Ligands

Development and Validation of a Bordetella pertussis Whole-Genome Screening Strategy

scientific article published on 02 April 2020

Development and validation of a broad scheme for prediction of HLA class II restricted T cell epitopes

scientific article published on 7 April 2015

Development and validation of a sample sparing strategy for HLA typing utilizing next generation sequencing

scientific article published on 28 May 2015

Development of a DNA Vaccine Designed to Induce Cytotoxic T Lymphocyte Responses to Multiple Conserved Epitopes in HIV-1 ⬇️

scientific article published on November 15, 2003

Development of a novel clustering tool for linear peptide sequences

scholarly article by Sandeep Kumar Dhanda et al published 6 August 2018 in Immunology

Development of a strategy and computational application to select candidate protein analogues with reduced HLA binding and immunogenicity

scientific article

Development of an epitope conservancy analysis tool to facilitate the design of epitope-based diagnostics and vaccines

scientific article

Development of envelope protein antigens to serologically differentiate Zika from dengue virus infection

scientific article published on 20 December 2017

Development of experimental carbohydrate-conjugate vaccines composed of Streptococcus pneumoniae capsular polysaccharides and the universal helper T-lymphocyte epitope (PADRE).

scientific article published in June 2004

Development of high potency universal DR-restricted helper epitopes by modification of high affinity DR-blocking peptides.

scientific article published in December 1994

Differences and similarities in the A2.1-restricted cytotoxic T cell repertoire in humans and human leukocyte antigen-transgenic mice

scientific article published on 01 January 1996

Differential Recognition of Mycobacterium tuberculosis-Specific Epitopes as a Function of Tuberculosis Disease History

scientific article

Differential T cell signaling induced by antagonist peptide-MHC complexes and the associated phenotypic responses

scientific article published on 01 March 1997

Differential activation of proliferation and cytotoxicity in human T-cell lymphotropic virus type I Tax-specific CD8 T cells by an altered peptide ligand

scientific article

Differential recognition of heat-shock protein dnaJ-derived epitopes by effector and Treg cells leads to modulation of inflammation in juvenile idiopathic arthritis.

scientific article published in May 2007

Differential signaling and hierarchical response thresholds induced by an immunodominant peptide of myelin basic protein and an altered peptide ligand in human T cells ⬇️

scientific article published on November 1, 1998

Discovering naturally processed antigenic determinants that confer protective T cell immunity

scientific article published on April 2013

Discovery and characterization of highly immunogenic and broadly recognized mimics of the HIV-1 CTL epitope Gag77-85.

scientific article

Disease extent and anti-tubercular treatment response correlates with Mycobacterium tuberculosis-specific CD4 T-cell phenotype regardless of HIV-1 status

scientific article published on 28 September 2020

Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency

scientific article published on 20 August 2018

Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ)

scientific article

Dissociation between epitope hierarchy and immunoprevalence in CD8 responses to vaccinia virus western reserve

scientific article published on June 2008

Divergent Motifs but Overlapping Binding Repertoires of Six HLA-DQ Molecules Frequently Expressed in the Worldwide Human Population ⬇️

scientific article published on October 1, 2010

Diverse recognition of conserved orthopoxvirus CD8+ T cell epitopes in vaccinated rhesus macaques

scientific article published on 14 June 2009

Diverse repertoire of HIV-1 p24-specific, IFN-gamma-producing CD4+ T cell clones following immune reconstitution on highly active antiretroviral therapy

scientific article published on 01 January 2003

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

scientific article

Early induction and maintenance of Env-specific T-helper cells following human immunodeficiency virus type 1 infection

scientific article

Effect of T-cell receptor antagonism on interaction between T cells and antigen-presenting cells and on T-cell signaling events

scientific article

Effect of conformational propensity of peptide antigens in their interaction with MHC class II molecules. Failure to document the importance of regular secondary structures

scientific article published in August 1989

Effect of pH on MHC class II-peptide interactions ⬇️

scientific article published on 01 February 1992

Effect of rheumatoid arthritis (RA) susceptibility genes on the immune response to viral citrullinated peptides in RA

scientific article published on 01 July 2012

Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection

scientific article

ElliPro: a new structure-based tool for the prediction of antibody epitopes

scientific article

Epitope Specific Antibodies and T Cell Receptors in the Immune Epitope Database

scientific article published on 20 November 2018

Epitope identification and vaccine design for cancer immunotherapy

scientific article

Epitope selection and development of peptide based vaccines to treat cancer

scientific article published on December 1995

Epitope-based vaccines: an update on epitope identification, vaccine design and delivery

scientific article

Epitope-specific airway-resident CD4+ T cell dynamics during experimental human RSV infection

scientific article published on 01 January 2020

Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies

scientific article published on 11 May 2017

Erratum for Verma et al., "Cytomegalovirus-Specific CD4 T Cells Are Cytolytic and Mediate Vaccine Protection".

scientific article published on 10 August 2017

Erratum: RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

scientific article published on 9 March 2016

Erratum: T cells from patients with Parkinson's disease recognize α-synuclein peptides

scientific article published in September 2017

Escape in one of two cytotoxic T-lymphocyte epitopes bound by a high-frequency major histocompatibility complex class I molecule, Mamu-A*02: a paradigm for virus evolution and persistence?

scientific article

Evaluating the immunogenicity of protein drugs by applying in vitro MHC binding data and the immune epitope database and analysis resource

scientific article

Evidence that recurrent Group A streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant Tfh cells

Evolution of the innate and adaptive immune response in women with acute Zika virus infection

scientific article published on 02 December 2019

Examining the independent binding assumption for binding of peptide epitopes to MHC-I molecules

scientific article

Expansion by self antigen is necessary for the induction of experimental autoimmune encephalomyelitis by T cells primed with a cross-reactive environmental antigen ⬇️

scientific article published on 01 October 1998

Experimental validation of the RATE tool for inferring HLA restrictions of T cell epitopes

scientific article

Extensive HLA class I allele promiscuity among viral CTL epitopes

scientific article published on September 2007

FAIR principles and the IEDB: short-term improvements and a long-term vision of OBO-foundry mediated machine-actionable interoperability

scientific article published on 19 February 2018

Failure to demonstrate long-lived MHC saturation both in vitro and in vivo. Implications for therapeutic potential of MHC-blocking peptides

scientific article published on May 1994

Fine restriction analysis and inhibition of antigen recognition in HLA-DQ-restricted T cells by major histocompatibility complex blockers and T cell receptor antagonists

scientific article published on 01 November 1993

Fine specificities of natural regulatory T cells after IVIG therapy in patients with Kawasaki disease

scientific article published on 30 March 2015

Five HLA-DP molecules frequently expressed in the worldwide human population share a common HLA supertypic binding specificity

scientific article

Footprints of antigen processing boost MHC class II natural ligand binding predictions

Footprints of antigen processing boost MHC class II natural ligand predictions

scholarly article by Carolina M Barra published in November 2018

Free ligand-induced dissociation of MHC-antigen complexes

scientific article published on 01 May 1991

Functional analysis of frequently expressed Chinese rhesus macaque MHC class I molecules Mamu-A1*02601 and Mamu-B*08301 reveals HLA-A2 and HLA-A3 supertypic specificities

scientific article

Functional classification of class II human leukocyte antigen (HLA) molecules reveals seven different supertypes and a surprising degree of repertoire sharing across supertypes

scientific article published on 9 February 2011

Generating quantitative models describing the sequence specificity of biological processes with the stabilized matrix method

scientific article

Generation of robust CD8+ T-cell responses against subdominant epitopes in conserved regions of HIV-1 by repertoire mining with mimotopes

scientific article

Generation of tumor-specific cytolytic T lymphocytes from peripheral blood of cervical cancer patients by in vitro stimulation with a synthetic human papillomavirus type 16 E7 epitope

scientific article published on December 1996

Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity

scientific article

Germ line tumor-associated immunoglobulin VH region peptides provoke a tumor-specific immune response without altering the response potential of normal B cells

scientific article

Gliadin activates HLA class I-restricted CD8+ T cells in celiac disease intestinal mucosa and induces the enterocyte apoptosis

scientific article published on 11 January 2008

Gliadin-Specific CD8+ T Cell Responses Restricted by HLA Class I A*0101 and B*0801 Molecules in Celiac Disease Patients

scientific article published in February 2017

Global Assessment of Dengue Virus-Specific CD4+ T Cell Responses in Dengue-Endemic Areas

scientific article published on 13 October 2017

Gorillas with spondyloarthropathies express an MHC class I molecule with only limited sequence similarity to HLA-B27 that binds peptides with arginine at P2.

scientific article

HIV Interferes with Mycobacterium tuberculosis Antigen Presentation in Human Dendritic Cells

scientific article published on 13 October 2016

HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease

scientific article

HLA DR4w4-binding motifs illustrate the biochemical basis of degeneracy and specificity in peptide-DR interactions ⬇️

scientific article published on September 15, 1993

HLA class I alleles are associated with peptide-binding repertoires of different size, affinity, and immunogenicity

scientific article

HLA class I binding of mutant EGFR peptides in NSCLC is associated with improved survival

scientific article published on 11 September 2020

HLA class I supertypes: a revised and updated classification

scientific article

HLA class I-restricted responses to vaccinia recognize a broad array of proteins mainly involved in virulence and viral gene regulation

scientific article

HLA expression in cancer: implications for T cell-based immunotherapy

scientific article

HLA shared epitope and ACPA: Just a marker or an active player? ⬇️

scientific article published on August 16, 2013

HLA tapasin independence: broader peptide repertoire and HIV control

scientific article published on 23 October 2020

HLA-A*01-restricted cytotoxic T-lymphocyte epitope from the Plasmodium falciparum circumsporozoite protein

scientific article published on April 2001

HLA-A*0201, HLA-A*1101, and HLA-B*0702 transgenic mice recognize numerous poxvirus determinants from a wide variety of viral gene products

scientific article published in October 2005

HLA-A2-restricted cytotoxic T lymphocyte responses to multiple Plasmodium falciparum sporozoite surface protein 2 epitopes in sporozoite-immunized volunteers.

scientific article published on July 1995

HLA-A2-restricted protection against lethal lymphocytic choriomeningitis

scientific article published on 13 December 2006

HLA-B*27 subtype specificity determines targeting and viral evolution of a hepatitis C virus-specific CD8+ T cell epitope

scientific article published on 23 August 2013

HLA-DR-promiscuous T cell epitopes from Plasmodium falciparum pre-erythrocytic-stage antigens restricted by multiple HLA class II alleles

scientific article

HLA-DR3 molecules can bind peptides carrying two alternative specific submotifs

scientific article published on June 1994

HLA-DR53 molecules are associated with susceptibility to celiac disease and selectively bind gliadin-derived peptides

scientific article published on August 1999

HLA-DRB1 Alleles Are Associated With Different Magnitudes of Dengue Virus-Specific CD4+ T-Cell Responses

scientific article published on 20 July 2016

HLA-binding peptides as a therapeutic approach for chronic HIV infection

scientific article published on 01 June 2000

HLA-independent heterogeneity of CD8+ T cell responses to MAGE-3, Melan-A/MART-1, gp100, tyrosinase, MC1R, and TRP-2 in vaccine-treated melanoma patients

scientific article published on 01 December 1998

Hepatitis C virus immune escape via exploitation of a hole in the T cell repertoire

scientific article

Hepatitis D Virus-Specific CD8+ T Cells Have a Memory-Like Phenotype Associated With Viral Immune Escape in Patients With Chronic Hepatitis D Virus Infection

scientific article published on 18 January 2019

Herpes simplex virus type 2 tegument proteins contain subdominant T-cell epitopes detectable in BALB/c mice after DNA immunization and infection

scientific article published on 04 March 2009

High affinity for class II molecules as a necessary but not sufficient characteristic of encephalitogenic determinants

scientific article published on 01 July 1992

High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV control

scientific article published on 13 July 2011

High-programmed death-1 levels on hepatitis C virus-specific T cells during acute infection are associated with viral persistence and require preservation of cognate antigen during chronic infection

scientific article

Host Transcriptomics as a Tool to Identify Diagnostic and Mechanistic Immune Signatures of Tuberculosis

scholarly article by Julie G Burel et al published 19 February 2019 in Frontiers in Immunology

Host resistance to pulmonary Mycobacterium tuberculosis infection requires CD153 expression

scientific article published on 10 September 2018

How T cells see antigen

scientific article published in November 1989

Howard Grey 1932-2019

scientific article published on 01 March 2020

Human CD4+ T cell responses to an attenuated tetravalent dengue vaccine parallel those induced by natural infection, in magnitude, HLA restriction and antigen specificity

scientific article (publication date: 14 December 2016)

Human CD8+ T-Cell Responses Against the 4 Dengue Virus Serotypes Are Associated With Distinct Patterns of Protein Targets

scientific article

Human CD8⁺ and CD4⁺ T cell memory to lymphocytic choriomeningitis virus infection

scientific article published on 7 September 2011

Human CTL epitopes encoded by human papillomavirus type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA-A*0201-binding peptides.

scientific article published on June 1995

Human Ebola virus infection results in substantial immune activation

scientific article

Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23

scientific article published on 01 December 2018

Human T Cell Response to Dengue Virus Infection

scientific article published on 04 September 2019

Human T-cell responses to HLA-A-restricted high binding affinity peptides of human papillomavirus type 18 proteins E6 and E7.

scientific article published in March 2001

Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses

scientific article published on 12 September 2013

Human class I supertypes and CTL repertoires extend to chimpanzees

scientific article published in October 1998

Human histocompatibility leukocyte antigen-binding supermotifs predict broadly cross-reactive cytotoxic T lymphocyte responses in patients with acute hepatitis ⬇️

scientific article published on August 1, 1997

Human immunome, bioinformatic analyses using HLA supermotifs and the parasite genome, binding assays, studies of human T cell responses, and immunization of HLA-A*1101 transgenic mice including novel adjuvants provide a foundation for HLA-A03 restri

scientific article

Human infection with Trypanosoma cruzi induces parasite antigen-specific cytotoxic T lymphocyte responses ⬇️

scientific article published on September 1, 1998

Human leukocyte antigen B27 selects for rare escape mutations that significantly impair hepatitis C virus replication and require compensatory mutations

scientific article

Human memory CTL response specific for influenza A virus is broad and multispecific

scientific article published in May 2000

Human rhinovirus-specific CD8 T cell responses target conserved and unusual epitopes

scientific article published on 23 November 2020

I-Ad-binding peptides derived from unrelated protein antigens share a common structural motif

scientific article

IEDB-3D: structural data within the immune epitope database

scientific article

IEDB-AR: immune epitope database-analysis resource in 2019

scientific article published on 01 July 2019

IMMU-41. H3.3K27M MUTATION-DERIVED NOVEL NEOANTIGEN – CHARACTERIZATION OF THE HLA-A2-BINDING EPITOPE AND A SPECIFIC T CELL RECEPTOR FOR DEVELOPMENT OF T CELL-BASED IMMUNOTHERAPY

scholarly article

IMMUNOCAT-a data management system for epitope mapping studies

scientific article (publication date: 2010)

IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

scientific article

Identification and characterization of CD4+ T cell epitopes after Shingrix vaccination

scientific article published on 30 September 2020

Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the Plasmodium falciparum AMA1 protein

scientific article

Identification of A2-restricted hepatitis C virus-specific cytotoxic T lymphocyte epitopes from conserved regions of the viral genome

scientific article published on May 1996

Identification of Db- and Kb-Restricted Subdominant Cytotoxic T-Cell Responses in Lymphocytic Choriomeningitis Virus-Infected Mice ⬇️

scientific article published on January 5, 1998

Identification of GP100-derived, melanoma-specific cytotoxic T-lymphocyte epitopes restricted by HLA-A3 supertype molecules by primaryin vitro immunization with peptide-pulsed dendritic cells ⬇️

scientific article published on November 9, 1998

Identification of HER2/neu-derived peptide epitopes recognized by gastric cancer-specific cytotoxic T lymphocytes ⬇️

scientific article published on 01 October 1998

Identification of HLA-A24 epitope peptides of carcinoembryonic antigen which induce tumor-reactive cytotoxic T lymphocyte

scientific article published on 01 January 1999

Identification of HLA-A3 and -B7-restricted CTL response to hepatitis C virus in patients with acute and chronic hepatitis C.

scientific article published on January 1999

Identification of HLA-A3-restricted cytotoxic T lymphocyte epitopes from carcinoembryonic antigen and HER-2/neu by primary in vitro immunization with peptide-pulsed dendritic cells

scientific article published on January 1999

Identification of Mycobacterial Ribosomal Proteins as Targets for CD4 T Cells That Enhance Protective Immunity in Tuberculosis

scholarly article published by Alessandro Sette in 2018

Identification of Mycobacterial RplJ/L10 and RpsA/S1 Proteins as Novel Targets for CD4+ T Cells

scientific article published on 23 January 2017

Identification of Novel Yellow Fever Class II Epitopes in YF-17D Vaccinees

scientific article published on 12 November 2020

Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data

scientific article

Identification of T. gondii epitopes, adjuvants, and host genetic factors that influence protection of mice and humans

scientific article

Identification of Zika virus epitopes reveals immunodominant and protective roles for dengue virus cross-reactive CD8+ T cells

scientific article (publication date: 13 March 2017)

Identification of a MAGE-2-encoded human leukocyte antigen-A24-binding synthetic peptide that induces specific antitumor cytotoxic T lymphocytes

scientific article published on 01 August 1999

Identification of an HSV-1/HSV-2 cross-reactive T cell determinant ⬇️

scientific article published on October 1, 1990

Identification of broad binding class I HLA supertype epitopes to provide universal coverage of influenza A virus

scientific article published on 10 March 2010

Identification of conserved and HLA promiscuous DENV3 T-cell epitopes

scientific article

Identification of immunodominant CD4-restricted epitopes co-located with antibody binding sites in individuals vaccinated with ALVAC-HIV and AIDSVAX B/E.

scientific article

Identification of minimal human MHC-restricted CD8+ T-cell epitopes within the Plasmodium falciparum circumsporozoite protein (CSP)

scientific article published in 2013

Identification of multiple HLA-A*0201-restricted cruzipain and FL-160 CD8+ epitopes recognized by T cells from chronically Trypanosoma cruzi-infected patients

scientific article

Identification of new HER2/neu-derived peptide epitopes that can elicit specific CTL against autologous and allogeneic carcinomas and melanomas

scientific article published on July 1999

Identification of new epitopes from four different tumor-associated antigens: recognition of naturally processed epitopes correlates with HLA-A*0201-binding affinity

scientific article

Identification of novel consensus CD4 T-cell epitopes from clade B HIV-1 whole genome that are frequently recognized by HIV-1 infected patients

scientific article published in November 2006

Identification of paramyosin T cell epitopes associated with human resistance to Schistosoma mansoni reinfection.

scientific article published in December 2005

Identification of potential CTL epitopes of tumor-associated antigen MAGE-1 for five common HLA-A alleles

scientific article

Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines

scientific article published on 28 December 2004

Identification of protective Lassa virus epitopes that are restricted by HLA-A2.

scientific article

Identification of seventeen new simian immunodeficiency virus-derived CD8+ T cell epitopes restricted by the high frequency molecule, Mamu-A*02, and potential escape from CTL recognition

scientific article published in October 2004

Identification of subdominant CTL epitopes of the GP100 melanoma-associated tumor antigen by primary in vitro immunization with peptide-pulsed dendritic cells.

scientific article published on February 1997

Identification of the peptide-binding motif recognized by the pigtail macaque class I MHC molecule Mane-A1*082:01 (Mane A*0301) ⬇️

scientific article published on January 26, 2012

Identifying Candidate Targets of Immune Responses in Zika Virus Based on Homology to Epitopes in Other Flavivirus Species

scientific article (publication date: 15 November 2016)

Identifying specificity groups in the T cell receptor repertoire

scientific article published on 21 June 2017

Imbalance of Regulatory and Cytotoxic SARS-CoV-2-Reactive CD4+ T Cells in COVID-19

scientific article published on 05 October 2020

Immune Epitope Database and Analysis Resource

Immune epitope database analysis resource

scientific article

Immune epitope database analysis resource (IEDB-AR).

scientific article published on 31 May 2008

Immune epitope mapping in the post-genomic era: lessons for vaccine development

scientific article published on 17 November 2006

Immunization with apical membrane antigen 1 confers sterile infection-blocking immunity against Plasmodium sporozoite challenge in a rodent model.

scientific article published on 08 July 2013

Immunization with the HBV core 18-27 epitope elicits CTL responses in humans expressing different HLA-A2 supertype molecules

scientific article published on November 1999

Immunodominance analysis of CTL responses to influenza PR8 virus reveals two new dominant and subdominant Kb-restricted epitopes

scientific article published in December 1996

Immunodominance changes as a function of the infecting dengue virus serotype and primary versus secondary infection

scientific article

Immunodominance in allergic T-cell reactivity to Japanese cedar in different geographic cohorts.

scientific article published in December 2016

Immunodominance of poxviral-specific CTL in a human trial of recombinant-modified vaccinia Ankara

scientific article published on 01 December 2005

Immunodominant Dengue Virus-Specific CD8+ T Cell Responses Are Associated with a Memory PD-1+ Phenotype

scientific article

Immunodominant epitopes in herpes simplex virus type 2 glycoprotein D are recognized by CD4 lymphocytes from both HSV-1 and HSV-2 seropositive subjects

scientific article published in November 2008

Immunodominant tuberculosis CD8 antigens preferentially restricted by HLA-B

scientific article

Immunogenic HLA-B7-restricted peptides of hTRT.

scientific article published on 31 October 2006

Immunogenic peptides can be detected in whole gluten by transamidating highly susceptible glutamine residues: implication in the search for gluten-free cereals

scientific article published on 11 January 2013

Immunogenicity and cross-reactivity of a representative ancestral sequence in hepatitis C virus infection

scientific article

Immunogenicity and tolerogenicity of hepatitis B virus structural and nonstructural proteins: implications for immunotherapy of persistent viral infections

scientific article

Immunogenicity of a recombinant protein containing the Plasmodium vivax vaccine candidate MSP1(19) and two human CD4+ T-cell epitopes administered to non-human primates (Callithrix jacchus jacchus).

scientific article published on 2 June 2006

Immunogenicity of self antigens is unrelated to MHC-binding affinity: T-cell determinant structure of Golli-MBP in the BALB/c mouse

scientific article published in November 2000

Immunological consequences of intragenus conservation of Mycobacterium tuberculosis T-cell epitopes

scientific article

Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection

scientific article published on 06 January 2021

Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus ⬇️

scientific article published on November 1, 1997

ImmunomeBrowser: a tool to aggregate and visualize complex and heterogeneous epitopes in reference proteins

scientific article published on 01 November 2018

Immunomic analysis of the repertoire of T-cell specificities for influenza A virus in humans

scientific article published on 08 October 2008

Immunoproteomic analysis of house dust mite antigens reveals distinct classes of dominant T cell antigens according to function and serological reactivity

scientific article published on 29 September 2016

Impact of Cysteine Residues on MHC Binding Predictions and Recognition by Tumor-Reactive T Cells

scientific article published on 22 June 2020

Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses

scientific article published in April 2006

Impact of distinct poxvirus infections on the specificities and functionalities of CD4+ T cell responses

scientific article

Improved immunogenicity of an immunodominant epitope of the HER-2/neu protooncogene by alterations of MHC contact residues

scientific article published on March 2004

Improved methods for predicting peptide binding affinity to MHC class II molecules

scientific article published on 6 January 2018

Improving MHC binding peptide prediction by incorporating binding data of auxiliary MHC molecules

scientific article

In silico prediction of peptides binding to multiple HLA-DR molecules accurately identifies immunodominant epitopes from gp43 of Paracoccidioides brasiliensis frequently recognized in primary peripheral blood mononuclear cell responses from sensitiz

scientific article

In vitro immunization and expansion of antigen-specific cytotoxic T lymphocytes for adoptive immunotherapy using peptide-pulsed dendritic cells.

scientific article published on January 1, 1998

In vitro induction of neoantigen-specific T cells in myelodysplastic syndrome, a disease with low mutational burden

scientific article published on 28 November 2020

In vitro induction of primary, antigen-specific CTL from human peripheral blood mononuclear cells stimulated with synthetic peptides

article

In vivo selection of a lymphocytic choriomeningitis virus variant that affects recognition of the GP33-43 epitope by H-2Db but not H-2Kb

scientific article published on June 2001

Increased CD8+ T cell responses to apoptotic T cell-associated antigens in multiple sclerosis

scientific article published on 27 July 2013

Induction of AIDS virus-specific CTL activity in fresh, unstimulated peripheral blood lymphocytes from rhesus macaques vaccinated with a DNA prime/modified vaccinia virus Ankara boost regimen

scientific article published in May 2000

Induction of anti-tumor cytotoxic T lymphocytes in normal humans using primary cultures and synthetic peptide epitopes

scientific article

Induction of antitumor cytotoxic T lymphocytes with a MAGE-3-encoded synthetic peptide presented by human leukocytes antigen-A24 ⬇️

scientific article published on October 15, 1997

Induction of tumor-reactive CTL from peripheral blood and tumor-infiltrating lymphocytes of melanoma patients by in vitro stimulation with an immunodominant peptide of the human melanoma antigen MART-1.

scientific article published on March 1995

Inflammation in Experimental Models of α-Synucleinopathies

scientific article published on 03 October 2020

Influenza-derived peptides cross-react with allergens and provide asthma protection.

scientific article published on 10 November 2017

Inhibition of antigen presentation in vitro and in vivo by MHC antagonist peptides

scientific article published on January 1990

Inhibition of experimental autoimmune encephalomyelitis induction in SJL/J mice by using a peptide with high affinity for IAs molecules ⬇️

scientific article published on September 15, 1990

Inhibition of protective immunity against Staphylococcus aureus infection by MHC-restricted immunodominance is overcome by vaccination

scientific article published on 01 April 2020

Insights into HLA-restricted T cell responses in a novel mouse model of dengue virus infection point toward new implications for vaccine design

scientific article

Integrating epitope data into the emerging web of biomedical knowledge resources

scientific article

Interaction of an immunodominant epitope with Ia molecules in T-cell activation

scientific article

Interaction of antigenic peptides with MHC and TCR molecules

scientific article published on September 1995

Interferon-gamma release assay for accurate detection of SARS-CoV-2 T cell response

scientific article published on 09 October 2020

Intestinal T cell responses to gluten peptides are largely heterogeneous: implications for a peptide-based therapy in celiac disease

scientific article published in April 2009

Invariant chain distinguishes between the exogenous and endogenous antigen presentation pathways

scientific article published in November 1990

Invariant chain peptides in most HLA-DR molecules of an antigen-processing mutant

scientific article published on December 11, 1992

Investigation of Outbreak-Specific Nonsynonymous Mutations on Ebolavirus GP in the Context of Known Immune Reactivity

scholarly article by Kerrie Vaughan et al published 2018 in Journal of Immunology Research

Involvement of Th1Th17 Cell Subpopulations in the Immune Responses of Mothers Who Gave Birth to Children with Congenital Zika Syndrome (CZS)

scientific article published on 27 January 2022

Isolation and characterization of naturally processed peptides bound by class II molecules and peptides presented by normal and mutant antigen-presenting cells

scientific article published on 01 January 1993

It's a lot of work to be nonallergic

scientific article published on 16 December 2016

Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction

scientific article published on 02 October 2020

Kinetic analysis of a complete poxvirus transcriptome reveals an immediate-early class of genes

scholarly article

Lack of evidence for BCG vaccine protection from severe COVID-19

scientific article published on 29 September 2020

Lack of evidence for post-vaccine onset of autoimmune/lymphoproliferative disorders, during a nine-month follow-up in multiply vaccinated Italian military personnel

scientific article published on 15 June 2017

Lack of evidence supporting a role of IFN-β and TGF-β in differential polarization of Bordetella pertussis specific-T cell responses

scientific article published on 28 September 2020

Large Scale Epitope Identification Screen and Its Potential Application to the Study of Alopecia Areata

scientific article published on 29 August 2017

Large-Scale Epitope Identification Screen and Its Potential Application to the Study of Alopecia Areata

scientific article published in January 2018

Limitations of Ab initio predictions of peptide binding to MHC class II molecules

scientific article

Limited Pulmonary Mucosal-Associated Invariant T Cell Accumulation and Activation during Mycobacterium tuberculosis Infection in Rhesus Macaques

scientific article published on 20 November 2018

Limited recognition of Mycobacterium tuberculosis-infected macrophages by polyclonal CD4 and CD8 T cells from the lungs of infected mice

scientific article published on 21 October 2019

Limited recognition ofMycobacterium tuberculosis-infected macrophages by polyclonal CD4 and CD8 T cells from the lungs of infected mice

scientific article

Lipopeptide particles as the immunologically active component of CTL inducing vaccines

scientific article published on 01 February 1999

Local CD4 and CD8 T-cell reactivity to HSV-1 antigens documents broad viral protein expression and immune competence in latently infected human trigeminal ganglia

scientific article

Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection

scientific article published on 16 May 2019

Low HLA binding of diabetes-associated CD8+ T-cell epitopes is increased by post translational modifications

scientific article published on 21 March 2018

Lymphocytic choriomeningitis virus infection yields overlapping CD4+ and CD8+ T-cell responses

scientific article published on October 2008

MAGE-6 encodes HLA-DRbeta1*0401-presented epitopes recognized by CD4+ T cells from patients with melanoma or renal cell carcinoma.

scientific article

MHC blocking peptides and T-cell receptor antagonists: novel paths to selective immunosuppression?

scientific article published on January 1995

MHC interaction and T cell recognition of carbohydrates and glycopeptides

scientific article

MHC-antigen-T cell interactions: an overview

scientific article published on July 1991

Machine learning reveals a non-canonical mode of peptide binding to MHC class II molecules.

scientific article published on 24 May 2017

Major Histocompatibility Complex Binding, Eluted Ligands, and Immunogenicity: Benchmark Testing and Predictions

scientific article published on 01 January 2019

Major histocompatibility complex binding peptides: a target for therapeutic development

scientific article

Major histocompatibility complex class II association and induction of T cell responses by carbohydrates and glycopeptides

scientific article published on January 1993

Majority of peptides binding HLA-A∗0201 with high affinity crossreact with other A2-supertype molecules ⬇️

scientific article published on November 1, 2001

Mapping immune responses to mRBP-3 1-16 peptide with altered peptide ligands

scientific article published on May 2006

Mapping the HLA-A24-restricted T-cell epitope peptide from a tumour-associated antigen HER2 / neu: possible immunotherapy for colorectal carcinomas

scientific article published on January 2001

Mapping the Human Memory B Cell and Serum Neutralizing Antibody Responses to DENV4 Infection and Vaccination

scientific article (publication date: 28 December 2016)

Mapping the MHC Class I-Spliced Immunopeptidome of Cancer Cells

scientific article published on 13 November 2018

Measurement of MHC/peptide interactions by gel filtration

scientific article

Measurement of MHC/peptide interactions by gel filtration or monoclonal antibody capture

scientific article

Meeting Report: NIH Workshop on the Tuberculosis Immune Epitope Database

scientific article published on 18 December 2007

Memory CD8+ T cells specific for a single immunodominant or subdominant determinant induced by peptide-dendritic cell immunization protect from an acute lethal viral disease

scientific article

Memory T cells in latent Mycobacterium tuberculosis infection are directed against three antigenic islands and largely contained in a CXCR3+CCR6+ Th1 subset

scientific article

Meta-analysis of all immune epitope data in the Flavivirus genus: inventory of current immune epitope data status in the context of virus immunity and immunopathology

scientific article

Metabolic Phenotypes of Response to Vaccination in Humans

scientific article published on 9 May 2017

Microbial epitopes act as altered peptide ligands to prevent experimental autoimmune encephalomyelitis

scientific article

Microbiota epitope similarity either dampens or enhances the immunogenicity of disease-associated antigenic epitopes.

scientific article

Mild SARS-CoV-2 infection in rhesus macaques is associated with viral control prior to antigen-specific T cell responses in tissues

scientific article published on 10 March 2022

Minimal Information About an Immuno-Peptidomics Experiment (MIAIPE).

scientific article published in June 2018

Minimal Information about MHC Multimers (MIAMM)

scientific article published on 18 January 2022

Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line

scientific article

Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand

scientific article published on April 1995

Molecular Signatures of Dengue Virus-Specific IL-10/IFN-γ Co-producing CD4 T Cells and Their Association with Dengue Disease

scientific article published on 01 December 2019

Molecular determinants of T cell epitope recognition to the common Timothy grass allergen

scientific article published on 16 June 2010

Molecular features of the hepatitis B virus nucleocapsid T-cell epitope 18-27: Interaction with HLA and T-cell receptor ⬇️

scientific article published on October 1, 1997

Most viral peptides displayed by class I MHC on infected cells are immunogenic

scientific article

Mucosal AIDS vaccine reduces disease and viral load in gut reservoir and blood after mucosal infection of macaques

article

Multiple Chlamydia pneumoniae antigens prime CD8+ Tc1 responses that inhibit intracellular growth of this vacuolar pathogen

scientific article published on September 2002

Mutating the anchor residues associated with MHC binding inhibits and deviates CD8+ T cell mediated protective immunity against malaria

scientific article published on 12 December 2006

Mycobacterial ESAT-6 and katG are recognized by sarcoidosis CD4+ T cells when presented by the American sarcoidosis susceptibility allele, DRB1*1101.

scientific article

Mycobacterium tuberculosis-specific CD4 T cells expressing CD153 inversely associate with bacterial load and disease severity in human tuberculosis

scientific article published on 16 July 2020

Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance

scientific article published in August 2008

Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

scientific article published on June 1994

Naturally processed HLA-DR3-restricted HHV-6B peptides are recognized broadly with polyfunctional and cytotoxic CD4 T-cell responses

scientific article published on 02 May 2019

Naturally processed peptides longer than nine amino acid residues bind to the class I MHC molecule HLA-A2.1 with high affinity and in different conformations

scientific article

Navigating diabetes-related immune epitope data: resources and tools provided by the Immune Epitope Database (IEDB)

scientific article

NetMHCpan, a method for MHC class I binding prediction beyond humans

scientific article published on 12 November 2008

NetMHCpan, a method for quantitative predictions of peptide binding to any HLA-A and -B locus protein of known sequence

scientific article

New epitopes in ovalbumin provide insights for cancer neoepitopes.

scientific article

New strategies for allergen T cell epitope identification: going beyond IgE

scientific article

Nontuberculous Mycobacteria and Heterologous Immunity to Tuberculosis

scientific article published on 01 August 2019

Normal tissue depresses while tumor tissue enhances human T cell responses in vivo to a novel self/tumor melanoma antigen, OA1

scientific article

Novel Plasmodium antigens identified via genome-based antibody screen induce protection associated with polyfunctional T cell responses.

scientific article published on 8 November 2017

Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy

scientific article published on 4 December 2017

Novel pan-DR-binding T cell epitopes of adenovirus induce pro-inflammatory cytokines and chemokines in healthy donors

scientific article published on 5 September 2006

OX40 drives protective vaccinia virus-specific CD8 T cells

scientific article published on December 2008

Occasional memory cytotoxic T-cell responses of patients with human papillomavirus type 16-positive cervical lesions against a human leukocyte antigen-A *0201-restricted E7-encoded epitope

scientific article published in February 1996

Of mice and humans: how good are HLA transgenic mice as a model of human immune responses?

scientific article

Ontogeny of the B- and T-cell response in a primary Zika virus infection of a dengue-naïve individual during the 2016 outbreak in Miami, FL.

scientific article published on 21 December 2017

Optimization of epitope processing enhances immunogenicity of multiepitope DNA vaccines

scientific article published on 01 September 2001

Optimizing use of tumor necrosis factor inhibitors in the management of immune-mediated inflammatory diseases

scientific article published on May 2010

Pan DR binding sequence provides T-cell help for induction of protective antibodies against Plasmodium yoelii sporozoites

scientific article

Pathogenic Autoimmunity in Atherosclerosis Evolves from Initially Protective ApoB-Reactive CD4+ T-Regulatory Cells

scientific article published on 24 July 2020

Patterns of cellular immunity associated with experimental infection with rDEN2Δ30 (Tonga/74) supports its suitability as a human DENV challenge strain

scientific article (publication date: February 2017)

Peanut-specific T cell responses in patients with different clinical reactivity

scientific article published in PLoS ONE

Peptide analogs with different affinites for MHC alter the cytokine profile of T helper cells

scientific article published on 01 May 1996

Peptide binding predictions for HLA DR, DP and DQ molecules

scientific article

Peptide binding to the most frequent HLA-A class I alleles measured by quantitative molecular binding assays

scientific article published on August 1994

Peptide stability in drug development. II. Effect of single amino acid substitution and glycosylation on peptide reactivity in human serum

scientific article published on 01 September 1993

Peptide vaccination using nonionic block copolymers induces protective anti-viral CTL responses

scientific article published in October 1999

Peptide-binding motifs associated with MHC molecules common in Chinese rhesus macaques are analogous to those of human HLA supertypes and include HLA-B27-like alleles

scientific article

Peptide-binding motifs of two common equine class I MHC molecules in Thoroughbred horses

scientific article

Peripheral T cell response to A-gliadin in celiac disease: differential processing and presentation capacities of Epstein-Barr-transformed B cells and fibroblasts

scientific article published on April 1994

Persistence of varicella zoster virus specific plasma cells in adult human bone marrow following childhood vaccination

scientific article published on 22 April 2020

Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome

scientific article published on 01 June 2020

Phenotype of SARS-CoV-2-specific T-cells in COVID-19 patients with acute respiratory distress syndrome

scientific article published on 18 April 2020

Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage

scientific article

Polyfunctional CD4+ T cell responses to immunodominant epitopes correlate with disease activity of virulent Salmonella

scientific article

Polyfunctional type-1, -2, and -17 CD8⁺ T cell responses to apoptotic self-antigens correlate with the chronic evolution of hepatitis C virus infection

scientific article

Pools of lipidated HTL-CTL constructs prime for multiple HBV and HCV CTL epitope responses ⬇️

scientific article published on May 1, 1998

Poor Antigen Processing of Poxvirus Particles Limits CD4 T Cell Recognition and Impacts Immunogenicity of the Inactivated Vaccine

scientific article published on 30 January 2019

Portrait of an optimist

scientific article

Positional bias of MHC class I restricted T-cell epitopes in viral antigens is likely due to a bias in conservation

scientific article

Potent immunogenic short linear peptide constructs composed of B cell epitopes and Pan DR T helper epitopes (PADRE) for antibody responses in vivo

scientific article published in March 1997

Poxvirus CD8+ T-cell determinants and cross-reactivity in BALB/c mice

scientific article

Practical, biochemical and evolutionary implications of the discovery of HLA class I supermotifs

scientific article published on June 1996

Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population

scientific article

Pre-existing immunity to SARS-CoV-2: the knowns and unknowns

scientific article published on 07 July 2020

Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis

scientific article published in January 2018

Predicting HLA CD4 Immunogenicity in Human Populations.

scientific article

Predicting T cell recognition of MHC class I restricted neoepitopes

scientific article published on 27 August 2018

Predicting population coverage of T-cell epitope-based diagnostics and vaccines

scientific article published on 17 March 2006

Preferential use of B7.2 and not B7.1 in priming of vaccinia virus-specific CD8 T cells

scientific article published on March 2009

Presence of effector CD8+ T cells in hepatitis C virus-exposed healthy seronegative donors

scientific article published on June 1999

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.

scientific article published on 03 October 2016

Previously undescribed grass pollen antigens are the major inducers of T helper 2 cytokine-producing T cells in allergic individuals

scientific article published on 11 February 2013

Prior Dengue virus exposure shapes T cell immunity to Zika virus in humans

scientific article published on 4 October 2017

Profiling MHC II immunopeptidome of blood-stage malaria reveals that cDC1 control the functionality of parasite-specific CD4 T cells.

scientific article published on 21 September 2017

Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules

scientific article published on September 1993

Prominent roles of secondary anchor residues in peptide binding to HLA-A24 human class I molecules ⬇️

scientific article published on November 1, 1995

Promiscuous Presentation and Recognition of Nucleosomal Autoepitopes in Lupus: Role of Autoimmune T Cell Receptor α Chain ⬇️

scientific article published on February 2, 1998

Properties of MHC class I presented peptides that enhance immunogenicity

scientific article

Protective Role of Cross-Reactive CD8 T Cells Against Dengue Virus Infection

scientific article published on 07 October 2016

Protein nanovaccine confers robust immunity against Toxoplasma

scientific article published on 5 September 2017

Protein sequence database for pathogenic arenaviruses

scientific article

Proteome-Wide Zika Virus CD4 T Cell Epitope and HLA Restriction Determination

scientific article published on 04 August 2020

Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses

scientific article published on 28 June 2019

Quantitating T cell cross-reactivity for unrelated peptide antigens

scientific article (publication date: October 2009)

Quantitative and Qualitative Perturbations of CD8+ MAITs in Healthy Mycobacterium tuberculosis-Infected Individuals

scientific article published on 04 June 2020

Quantitative peptide binding motifs for 19 human and mouse MHC class I molecules derived using positional scanning combinatorial peptide libraries

scientific article

Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan

scientific article

Query enhancement through the practical application of ontology: the IEDB and OBI.

scientific article published on 15 April 2013

RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

scientific article

Random association between the peptide repertoire of A2.1 class I and several different DR class II molecules ⬇️

scientific article published on December 1, 1991

Rapid Induction and Maintenance of Virus-Specific CD8+ TEMRA and CD4+ TEM Cells Following Protective Vaccination Against Dengue Virus Challenge in Humans

scientific article published on 24 March 2020

Rational design of a multiepitope vaccine encoding T-lymphocyte epitopes for treatment of chronic hepatitis B virus infections

scientific article

Rationally engineered therapeutic proteins with reduced immunogenicity

scientific article published in March 2005

Recognition of Class II MHC Peptide Ligands That Contain β-Amino Acids

scientific article published on 07 August 2019

Recognition of multiple peptide cores by a single T cell receptor ⬇️

scientific article published on August 1, 1995

Recognition of variant HIV-1 epitopes from diverse viral subtypes by vaccine-induced CTL

scientific article published on 01 August 2004

Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells.

scientific article published in February 2019

Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine

scientific article

Regulatory CD4+ T Cells Recognize MHC-II-Restricted Peptide Epitopes of Apolipoprotein B.

scientific article published on 27 March 2018

Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity

scientific article

Reply

scientific article published on 30 July 2016

Reply to Satheshkumar and Moss: Poxvirus transcriptome analysis.

scholarly article

Reproducibility and conflicts in immune epitope data

scientific article

Response to Comment on "A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood".

scientific article published in October 2016

Reverse Vaccinology: Developing Vaccines in the Era of Genomics ⬇️

scientific article published on October 29, 2010

Reversion of CTL escape–variant immunodeficiency viruses in vivo

article

Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus type 16 E6 and E7 proteins

scientific article published on 01 April 1994

Role of preimmunization virus sequences in cellular immunity in HIV-infected patients during HIV type 1 MN recombinant gp160 immunization

scientific article published in December 1998

Roles for the adaptive immune system in Parkinson's and Alzheimer's diseases

scientific article published on 17 August 2019

SARS-CoV-2 infection generates tissue-localized immunological memory in humans

scientific article published on 19 November 2021

SARS-CoV-2 infection induces germinal center responses with robust stimulation of CD4 T follicular helper cells in rhesus macaques

scientific article published on 08 July 2020

SARS-CoV-2 infection induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques

scientific article published on 14 August 2020

SARS-CoV-2 vaccination enhances the effector qualities of spike-specific T cells induced by COVID-19

scientific article published on 8 December 2023

SIV-infected Chinese-origin rhesus macaques express specific MHC class I alleles in either elite controllers or normal progressors ⬇️

scientific article published on August 1, 2011

Safety and immunogenicity of the adjunct therapeutic vaccine ID93 + GLA-SE in adults who have completed treatment for tuberculosis: a randomised, double-blind, placebo-controlled, phase 2a trial

scientific article published on 08 December 2020

Safety and immunogenicity of the tetravalent, live-attenuated dengue vaccine Butantan-DV in adults in Brazil: a two-step, double-blind, randomised placebo-controlled phase 2 trial

scientific article published on 24 March 2020

Sculpting MHC class II-restricted self and non-self peptidome by the class I Ag-processing machinery and its impact on Th-cell responses

scientific article published on 5 March 2013

Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection

scientific article

Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities

scientific article published on June 2008

Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans

scientific article

Selective immunosuppression by administration of major histocompatibility complex (MHC) class II-binding peptides. I. Evidence for in vivo MHC blockade preventing T cell activation

scientific article published on May 1992

Self peptide requirement for class II major histocompatibility complex allorecognition

scientific article published on October 1991

Sequence-based HLA-A, B, C, DP, DQ, and DR typing of 100 Luo infants from the Boro area of Nyanza Province, Kenya

scientific article published on 15 March 2017

Sequence-based HLA-A, B, C, DP, DQ, and DR typing of 159 individuals from the Worcester region of the Western Cape province of South Africa

scientific article published on 2 February 2018

Sequence-based HLA-A, B, C, DP, DQ, and DR typing of 339 adults from Managua, Nicaragua

scientific article published on 6 November 2017

Sequence-based HLA-A, B, C, DP, DQ, and DR typing of 496 adults from San Diego, California, USA

scientific article published on 29 September 2018

Sequence-based HLA-A, B, C, DP, DQ, and DR typing of 714 adults from Colombo, Sri Lanka

scientific article published on 28 December 2017

Several common HLA-DR types share largely overlapping peptide binding repertoires ⬇️

scientific article published on April 1, 1998

Simultaneous prediction of binding capacity for multiple molecules of the HLA B44 supertype

scientific article published in December 2003

Single-Cell Transcriptomic Analysis of SARS-CoV-2 Reactive CD4 + T Cells

scientific article published on 07 July 2020

Single-cell transcriptomic analysis of SARS-CoV-2 reactive CD4 + T cells

scientific article published on 13 June 2020

Single-cell transcriptomic analysis of allergen-specific T cells in allergy and asthma

scientific article published on 01 June 2020

Specific binding of leukemia oncogene fusion protein peptides to HLA class I molecules.

scientific article published in May 1995

Specificity and degeneracy in peptide binding to HLA-B7-like class I molecules

scientific article published on 01 October 1996

Spleen Cells from Young but Not Old Immunized Mice Eradicate Large Established Cancers ⬇️

scientific article published on March 13, 2012

Spreading of HIV-specific CD8+ T-cell repertoire in long-term nonprogressors and its role in the control of viral load and disease activity

scientific article

Sterile immunity to malaria after DNA prime/adenovirus boost immunization is associated with effector memory CD8+T cells targeting AMA1 class I epitopes

scientific article

Strategies to query and display allergy-derived epitope data from the immune epitope database

scientific article

Strong similarities in antigen fine specificity among DRB1* 1302-restricted tetanus toxin tt830-843-specific TCRs in spite of highly heterogeneous CDR3.

scientific article published on April 1995

Structural analysis of peptides capable of binding to more than one Ia antigen

scientific article published on January 1989

Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid

scientific article published on 2 April 2008

Structural basis for the presentation of tumor-associated MHC class II-restricted phosphopeptides to CD4+ T cells

scientific article

Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells

scientific article published in Nature

Structural characteristics of peptides required for their interaction with IAd.

scientific article published on January 1988

Structural features of peptide analogs of human histocompatibility leukocyte antigen class I epitopes that are more potent and immunogenic than wild-type peptide

scientific article

Structural requirements and biological significance of interactions between peptides and the major histocompatibility complex

scientific article published on 01 June 1989

Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones

scientific article

Structural requirements for the interaction between peptide antigens and I-Ed molecules

scientific article published in November 1989

Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au

scientific article

Structure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicity

scientific article

Studies on the nature of physiologically processed antigen and on the conformation of peptides required for interaction with MHC.

scientific article

Substantial gaps in knowledge of Bordetella pertussis antibody and T cell epitopes relevant for natural immunity and vaccine efficacy

scientific article published on 12 February 2014

Supermotif peptide binding and degeneracy of MHC: peptide recognition in an EBV peptide-specific CTL response with highly restricted TCR usage

scientific article

Synthetic antigenic peptides as a new strategy for immunotherapy of cancer

scientific article published on January 1, 1995

Synthetic peptides derived from the melanocyte-stimulating hormone receptor MC1R can stimulate HLA-A2-restricted cytotoxic T lymphocytes that recognize naturally processed peptides on human melanoma cells

scientific article published on October 1997

Synthetic peptides in the analysis of T cell interactions

scientific article published on 01 January 1984

Synthetic peptides in the analysis of the induction and regulation of delayed-type hypersensitivity to lysozyme

scientific article published on 01 January 1985

T Cell Epitope Predictions

scientific article published on 11 February 2020

T Cell Recognition of Flanking Residues of Murine Invariant Chain-Derived CLIP Peptide Bound to MHC Class II ⬇️

scientific article published on August 25, 1998

T Cell Responses to Neural Autoantigens Are Similar in Alzheimer's Disease Patients and Age-Matched Healthy Controls

scientific article published on 27 August 2020

T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus

scientific article

T cell neoepitope discovery in colorectal cancer by high throughput profiling of somatic mutations in expressed genes

scientific article published on 17 December 2015

T cell receptor antagonism mediated by interaction between T cell receptor junctional residues and peptide antigen analogues

scientific article published on 01 May 1993

T cell receptor antagonist peptides are highly effective inhibitors of experimental allergic encephalomyelitis

scientific article published on April 1994

T cell receptor cross-recognition of an HIV-1 CD8+ T cell epitope presented by closely related alleles from the HLA-A3 superfamily

article

T cell recognition of immunodominant and cryptic proteolipid protein epitopes in humans.

scientific article published on July 1995

T cell responses induced by attenuated flavivirus vaccination are specific and show limited cross-reactivity with other flavivirus species

scientific article published on 04 March 2020

T cell responses to known allergen proteins are differently polarized and account for a variable fraction of total response to allergen extracts

scientific article

T cells from patients with Parkinson's disease recognize α-synuclein peptides

scientific article

T-cell epitope conservation across allergen species is a major determinant of immunogenicity

scientific article published on 13 February 2016

T-cell immunity to infection with dengue virus in humans

scientific article

T-cell memory responses elicited by yellow fever vaccine are targeted to overlapping epitopes containing multiple HLA-I and -II binding motifs

scientific article

T-cell recognition is shaped by epitope sequence conservation in the host proteome and microbiome

scientific article published on 20 January 2016

T-lymphocyte epitope identification and their use in vaccine development for HIV-1.

scientific article

TCR antagonism and T cell tolerance can be independently induced in a DR-restricted, hemagglutinin-specific T cell clone

scientific article published on March 1994

Targeting OX40 promotes lung-resident memory CD8 T cell populations that protect against respiratory poxvirus infection

scientific article

Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals

scientific article published on 20 May 2020

Tat-vaccinated macaques do not control simian immunodeficiency virus SIVmac239 replication

scientific article

TepiTool: A Pipeline for Computational Prediction of T Cell Epitope Candidates

scientific article published on August 2016

Termination of peripheral tolerance to a T cell epitope by heteroclitic antigen analogues ⬇️

scientific article published on August 15, 1998

Th1 versus Th2 T cell polarization by whole-cell and acellular childhood pertussis vaccines persists upon re-immunization in adolescence and adulthood

scientific article published on 14 May 2016

Th1/Th17 polarization persists following whole-cell pertussis vaccination despite repeated acellular boosters

scientific article published on 06 August 2018

The CD4+ T-cell epitope-binding register is a critical parameter when generating functional HLA-DR tetramers with promiscuous peptides

scientific article published on June 2010

The CD8+ T-cell response to lymphocytic choriomeningitis virus involves the L antigen: uncovering new tricks for an old virus

scientific article published on 28 February 2007

The Challenge of Distinguishing Cell-Cell Complexes from Singlet Cells in Non-Imaging Flow Cytometry and Single-Cell Sorting

scientific article published on 13 May 2020

The HLA molecules DQA1*0501/B1*0201 and DQA1*0301/B1*0302 share an extensive overlap in peptide binding specificity

scientific article (publication date: November 2002)

The HLA-A0207 Peptide Binding Repertoire is Limited to a Subset of the A0201 Repertoire ⬇️

scientific article published on November 1, 1997

The Human Immunopeptidome Project: A Roadmap to Predict and Treat Immune Diseases

scientific article published on 19 November 2019

The Identification of Allergen-Derived T Cell Epitopes

scientific article published on 01 January 2018

The Immune Epitope Database (IEDB): 2018 update

scholarly article by Randi Vita et al published 24 October 2018 in Nucleic Acids Research

The Immune Epitope Database and Analysis Resource Program 2003-2018: reflections and outlook

scientific article published on 25 November 2019

The Immune Epitope Database and Analysis Resource in Epitope Discovery and Synthetic Vaccine Design

scientific article

The Immune Epitope Database: How Data Are Entered and Retrieved

scientific article

The Length Distribution of Class I-Restricted T Cell Epitopes Is Determined by Both Peptide Supply and MHC Allele-Specific Binding Preference

scientific article published on 18 January 2016

The Multi-epitope Approach for Immunotherapy for Cancer: Identification of Several CTL Epitopes from Various Tumor-Associated Antigens Expressed on Solid Epithelial Tumors ⬇️

scientific article published on January 1, 1998

The RBD Of The Spike Protein Of SARS-Group Coronaviruses Is A Highly Specific Target Of SARS-CoV-2 Antibodies But Not Other Pathogenic Human and Animal Coronavirus Antibodies

scientific article published on 10 May 2020

The SysteMHC Atlas project

scientific article published on 29 July 2017

The T210M Substitution in the HLA-a*02:01 gp100 Epitope Strongly Affects Overall Proteasomal Cleavage Site Usage and Antigen Processing

scientific article

The TB-specific CD4(+) T cell immune repertoire in both cynomolgus and rhesus macaques largely overlap with humans

scientific article published on 28 August 2015

The Use of the Immune Epitope Database to Study Autoimmune Epitope Data Related to Alopecia Areata

scientific article

The association of allergic sensitization patterns in early childhood with disease manifestations and immunological reactivity at 10 years of age

scientific article published on 29 May 2019

The common equine class I molecule Eqca-1*00101 (ELA-A3.1) is characterized by narrow peptide binding and T cell epitope repertoires

scientific article

The cytotoxic T lymphocyte response to multiple hepatitis B virus polymerase epitopes during and after acute viral hepatitis

scientific article

The design and implementation of the immune epitope database and analysis resource

scientific article published on 14 May 2005

The effect of acylation with fatty acids and other modifications on HLA class II:peptide binding and T cell stimulation for three model peptides.

scientific article published on 14 May 2018

The hepatitis B virus-specific CTL responses induced in humans by lipopeptide vaccination are comparable to those elicited by acute viral infection

scientific article published on August 1, 1997

The high frequency Indian rhesus macaque MHC class I molecule, Mamu-B*01, does not appear to be involved in CD8+ T lymphocyte responses to SIVmac239

scientific article published on 01 November 2005

The human CD8+ T cell responses induced by a live attenuated tetravalent dengue vaccine are directed against highly conserved epitopes

scientific article

The identification of potentially pathogenic and therapeutic epitopes from common human allergens

scientific article published on 15 November 2012

The immune epitope database (IEDB) 3.0.

scientific article

The immune epitope database 2.0.

scientific article

The immune epitope database and analysis resource: from vision to blueprint

scientific article

The immune epitope database and analysis resource: from vision to blueprint.

scientific article published in January 2004

The immune epitope database: a historical retrospective of the first decade

scientific article published on October 2012

The inhibition of different T cell lines specific for the same antigen with TCR antagonist peptides.

scientific article published on December 1993

The interaction between protein-derived immunogenic peptides and Ia.

scientific article published on August 1987

The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design

scientific article

The minimal number of class II MHC-antigen complexes needed for T cell activation

scientific article

The most common Chinese rhesus macaque MHC class I molecule shares peptide binding repertoire with the HLA-B7 supertype

scientific article

The nucleocapsid protein of Rift Valley fever virus is a potent human CD8+ T cell antigen and elicits memory responses

scientific article

The optimization of helper T lymphocyte (HTL) function in vaccine development

scientific article

The peptide-binding motif for the human transporter associated with antigen processing

scientific article

The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients

scientific article published on 01 June 2020

The relation between major histocompatibility complex (MHC) restriction and the capacity of Ia to bind immunogenic peptides

scientific article

The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes

scientific article published on December 1994

The role of MHC class I allele Mamu-A*07 during SIV(mac)239 infection

scientific article

The self-directed T cell repertoire against mouse lysozyme reflects the influence of the hierarchy of its own determinants and can be engaged by a foreign lysozyme

scientific article published on October 1999

The smallpox vaccine induces an early neutralizing IgM response

scientific article published on 12 October 2009

The use of peptide analogs with improved stability and MHC binding capacity to inhibit antigen presentation in vitro and in vivo

scientific article

TiArA: a virtual appliance for the analysis of Tiling Array data

scientific article

Tolerance to a self peptide from the third hypervariable region of the Es beta chain. Implications for molecular mimicry models of autoimmune disease

scientific article published in September 1991

Tolerogenic immune responses to novel T-cell epitopes from heat-shock protein 60 in juvenile idiopathic arthritis

scientific article published in July 2005

Towards a consensus on datasets and evaluation metrics for developing B-cell epitope prediction tools

scientific article

Towards an immunosense vaccine to prevent toxoplasmosis: protective Toxoplasma gondii epitopes restricted by HLA-A*0201

scientific article

Towards defining molecular determinants recognized by adaptive immunity in allergic disease: an inventory of the available data

scientific article

Toxoplasma gondii HLA-B*0702-restricted GRA7(20-28) peptide with adjuvants and a universal helper T cell epitope elicits CD8(+) T cells producing interferon-γ and reduces parasite burden in HLA-B*0702 mice

scientific article published on 12 October 2011

Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove

scientific article published on 29 January 2016

Transcriptional Profiling of Th2 Cells Identifies Pathogenic Features Associated with Asthma

scientific article published on 6 June 2016

Transcriptional profile of tuberculosis antigen-specific T cells reveals novel multifunctional features

scientific article

Transcriptomic Analysis of CD4+ T Cells Reveals Novel Immune Signatures of Latent Tuberculosis

scientific article published on 30 March 2018

Transcriptomic immune profiles of human flavivirus-specific T-cell responses

scientific article published on 28 November 2019

Transient Immune Activation in BCG-Vaccinated Infant Rhesus Macaques Is Not Sufficient to Influence Oral Simian Immunodeficiency Virus Infection

scientific article published on 12 October 2019

Truncation analysis of several DR binding epitopes ⬇️

scientific article published on February 15, 1991

Tumor-associated carbohydrate antigens: a possible avenue for cancer prevention

scientific article published in August 2005

Two MHC class I molecules associated with elite control of immunodeficiency virus replication, Mamu-B*08 and HLA-B*2705, bind peptides with sequence similarity

scientific article

Two distinct HLA-A*0101-specific submotifs illustrate alternative peptide binding modes

scientific article published on January 1997

Two kinetic patterns of epitope-specific CD8 T-cell responses following murine gammaherpesvirus 68 infection

scientific article

Uncovering subdominant cytotoxic T-lymphocyte responses in lymphocytic choriomeningitis virus-infected BALB/c mice.

scientific article published in July 1997

Unexpected diversity of cellular immune responses against Nef and Vif in HIV-1-infected patients who spontaneously control viral replication

scientific article

Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA.

scientific article

Universal influenza DNA vaccine encoding conserved CD4+ T cell epitopes protects against lethal viral challenge in HLA-DR transgenic mice

scientific article published on 4 November 2009

Urinary Peptides As a Novel Source of T Cell Allergen Epitopes.

scientific article

Utilization of MHC class I transgenic mice for development of minigene DNA vaccines encoding multiple HLA-restricted CTL epitopes

scientific article published on 01 April 1999

Utilization of genomic sequence information to develop malaria vaccines ⬇️

scientific article published on November 1, 2003

Vaccination to modulate atherosclerosis

scientific article published on 16 February 2015

Vaccinia virus-specific CD4+ T cell responses target a set of antigens largely distinct from those targeted by CD8+ T cell responses

scientific article

Variability in German Cockroach Extract Composition Greatly Impacts T Cell Potency in Cockroach-Allergic Donors

article

Waning Immunity and Microbial Vaccines-Workshop of the National Institute of Allergy and Infectious Diseases

scientific article published on 10 May 2017

Widespread Tau-Specific CD4 T Cell Reactivity in the General Population

scientific article published on 13 May 2019

ZikaPLAN: addressing the knowledge gaps and working towards a research preparedness network in the Americas

scientific article published on 01 January 2019

α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson's disease

scientific article published on 20 April 2020

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