List of works - Adnane Achour

A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition

scientific article

A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity

scientific article published on 21 April 2005

A structural basis for LCMV immune evasion: subversion of H-2D(b) and H-2K(b) presentation of gp33 revealed by comparative crystal structure.Analyses

scientific article

A three-dimensional model of the Fas/APO-1 molecule: cross-reactivity of anti-Fas antibodies explained by structural mimicry of antigenic sites

scientific article published on 01 February 1998

Altered MHC class I presented peptide repertoire is not sufficient to induce NK cell mediated F1-hybrid resistance.

scientific article published on August 1995

Binding of subdomains 1/2 of PfEMP1-DBL1α to heparan sulfate or heparin mediates Plasmodium falciparum rosetting

scientific article

Boosting of HIV-1 neutralizing antibody responses by a distally related retroviral envelope protein

scientific article

Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8+ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection

scientific article published on 02 July 2018

Cis association of leukocyte Ig-like receptor 1 with MHC class I modulates accessibility to antibodies and HCMV UL18.

scientific article published on 4 March 2013

Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic β 2 -Microglobulin

scientific article

Cloning, expression, and purification of HIV-2 gp125: A target for HIV vaccination.

scientific article published in June 2005

Cloning, expression, purification, crystallization and preliminary X-ray analysis of the pilus-associated sortase C from Streptococcus pneumoniae.

scientific article published on 25 December 2008

Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication

scientific article

Crystal Structure of the HIV-2 Neutralizing Fab Fragment 7C8 with High Specificity to the V3 Region of gp125

scientific article

Crystal structure of the dog lipocalin allergen Can f 2: implications for cross-reactivity to the cat allergen Fel d 4

scientific article

Crystal structure of the major Malassezia sympodialis allergen Mala s 1 reveals a beta-propeller fold: a novel fold among allergens

scientific article

Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity

scientific article published on 18 December 2017

Crystallization and preliminary crystallographic data of a Fel d 1 (1+2) construct corresponding to the major allergen from cat.

scientific article

Crystallization and preliminary crystallographic study of the yeast Malassezia sympodialis allergen Mala s 1

scientific article published on 27 January 2006

Deletion of the V1/V2 region does not increase the accessibility of the V3 region of recombinant gp125

scientific article published on 01 April 2006

Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100

scientific article

Designing a multimer allergen for diagnosis and immunotherapy of dog allergic patients

scientific article

Detecting ligand interactions in real time on living bacterial cells.

scientific article published on 17 March 2018

Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.

scientific article published in May 2004

Expression, refolding and crystallization of murine MHC class I H-2Db in complex with human beta2-microglobulin

scientific article published on 24 November 2005

Fine characterization of a V3-region neutralizing epitope in human immunodeficiency virus type 2.

scientific article

Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis

scientific article

Generation of neutralizing antibodies and divergence of SIVmac239 in cynomolgus macaques following short-term early antiretroviral therapy

scientific article (publication date: 2010)

Human cytomegalovirus-derived protein UL18 alters the phenotype and function of monocyte-derived dendritic cells

scientific article published on 26 September 2007

Immune modulation by the human cytomegalovirus-encoded molecule UL18, a mystery yet to be solved.

scientific article published on January 2008

Increased sensitivity to broadly neutralizing antibodies of end-stage disease R5 HIV-1 correlates with evolution in Env glycosylation and charge

scientific article

Inflammation-associated nitrotyrosination affects TCR recognition through reduced stability and alteration of the molecular surface of the MHC complex

scientific article

LILRB1 polymorphisms influence posttransplant HCMV susceptibility and ligand interactions.

scientific article published on 12 March 2018

MHC class I recognition by NK receptors in the Ly49 family is strongly influenced by the beta 2-microglobulin subunit.

scientific article published in June 2001

MICA-129 Dimorphism and Soluble MICA Are Associated With the Progression of Multiple Myeloma.

scientific article published in May 2018

Malondialdehyde modification of myelin oligodendrocyte glycoprotein leads to increased immunogenicity and encephalitogenicity

scientific article published on 01 July 2007

Maternal MHC regulates generation of pathogenic antibodies and fetal MHC-encoded genes determine susceptibility in congenital heart block

scientific article published on 9 August 2010

Melanocortin 1 Receptor-derived peptides are efficiently recognized by cytotoxic T lymphocytes from melanoma patients

scientific article published on 12 October 2013

Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation.

scientific article published on 4 March 2015

Migratory activation of parasitized dendritic cells by the protozoan Toxoplasma gondii 14-3-3 protein

scientific article

Multiple polymorphisms affect expression and function of the neuropeptide S receptor (NPSR1).

scientific article

Murine class I major histocompatibility complex H–2Dd: expression, refolding and crystallization

article

Mutational analysis of amino acid residues involved in IgE-binding to the Malassezia sympodialis allergen Mala s 11

scientific article published on 14 October 2008

NK cell inhibitory receptor Ly-49C residues involved in MHC class I binding.

scientific article

Natural killer cell tolerance persists despite significant reduction of self MHC class I on normal target cells in mice

scientific article

Nitration of MOG diminishes its encephalitogenicity depending on MHC haplotype.

scientific article

PD-1 expression on mouse intratumoral NK cells and its effects on NK cell phenotype

scientific article published in 2022

Peptide dependency and selectivity of the NK cell inhibitory receptor Ly-49C

scientific article published on 01 September 1999

Peptide-independent stabilization of MHC class I molecules breaches cellular quality control

scientific article

Plasmodium falciparum rosetting epitopes converge in the SD3-loop of PfEMP1-DBL1α.

scientific article

Primary HIV-1 R5 isolates from end-stage disease display enhanced viral fitness in parallel with increased gp120 net charge

scientific article

Production, crystallization and preliminary X-ray diffraction analysis of the allergen Can f 2 from Canis familiaris.

scientific article published on 24 April 2009

Production, crystallization and preliminary crystallographic study of the major cat allergen Fel d 1.

scientific article published on 23 May 2003

Production, purification, crystallization and preliminary X-ray diffraction analysis of the HIV-2-neutralizing V3 loop-specific Fab fragment 7C8.

scientific article published on 27 June 2009

Proline substitution independently enhances H-2D(b) complex stabilization and TCR recognition of melanoma-associated peptides

scientific article

PyTMs: a useful PyMOL plugin for modeling common post-translational modifications

scientific article

SAMHD1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity

scientific article published on 28 September 2020

Spontaneous mutations in the human CMV HLA class I homologue UL18 affect its binding to the inhibitory receptor LIR-1/ILT2/CD85j

scientific article published on 01 March 2006

Structural Basis of the Differential Stability and Receptor Specificity of H-2Db in Complex with Murine versus Human β2-Microglobulin

article

Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of Streptococcus pneumoniae

scientific article

Structural and functional studies of Spr1654: an essential aminotransferase in teichoic acid biosynthesis in Streptococcus pneumoniae.

scientific article published in April 2018

Structural characterization of the tetrameric form of the major cat allergen Fel d 1

scientific article

Structural elements underlying the high binding affinity of human cytomegalovirus UL18 to leukocyte immunoglobulin-like receptor-1

scientific article

T Cell Tolerance Based on Avidity Thresholds Rather Than Complete Deletion Allows Maintenance of Maximal Repertoire Diversity

scientific article published on 01 July 2000

T-cell receptor-HLA-DRB1 associations suggest specific antigens in pulmonary sarcoidosis.

scientific article published on 19 November 2015

TAP-independent self-peptides enhance T cell recognition of immune-escaped tumors

scientific article published on 19 January 2016

The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation

scientific article

The Immunogenicity of a Proline-Substituted Altered Peptide Ligand toward the Cancer-Associated TEIPP Neoepitope Trh4 Is Unrelated to Complex Stability.

scientific article published on 5 March 2018

The MHC Class I Cancer-Associated Neoepitope Trh4 Linked with Impaired Peptide Processing Induces a Unique Noncanonical TCR Conformer

scientific article

The basic keratin 10-binding domain of the virulence-associated pneumococcal serine-rich protein PsrP adopts a novel MSCRAMM fold

scientific article

The crystal structure of the major cat allergen Fel d 1, a member of the secretoglobin family

scientific article

The crystal structure of the major pneumococcal autolysin LytA in complex with a large peptidoglycan fragment reveals the pivotal role of glycans for lytic activity

scientific article published on 7 June 2016

Three-Dimensional Structure of Fel d 1, the Major Allergen in Cat

scientific article published on 01 September 2003

Tuning antiviral CD8 T-cell response via proline-altered peptide ligand vaccination

scientific article published on 04 May 2020

Two crystal structures of pneumococcal pilus sortase C provide novel insights into catalysis and substrate specificity

scientific article

Viral and cellular proteins containing FGDF motifs bind G3BP to block stress granule formation

scientific article published on 6 February 2015

List of works by Adnane Achour

A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition

A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity

A structural basis for LCMV immune evasion: subversion of H-2D(b) and H-2K(b) presentation of gp33 revealed by comparative crystal structure.Analyses

A three-dimensional model of the Fas/APO-1 molecule: cross-reactivity of anti-Fas antibodies explained by structural mimicry of antigenic sites

Altered MHC class I presented peptide repertoire is not sufficient to induce NK cell mediated F1-hybrid resistance.

Binding of subdomains 1/2 of PfEMP1-DBL1α to heparan sulfate or heparin mediates Plasmodium falciparum rosetting

Boosting of HIV-1 neutralizing antibody responses by a distally related retroviral envelope protein

Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8+ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection

Cis association of leukocyte Ig-like receptor 1 with MHC class I modulates accessibility to antibodies and HCMV UL18.

Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic β 2 -Microglobulin

Cloning, expression, and purification of HIV-2 gp125: A target for HIV vaccination.

Cloning, expression, purification, crystallization and preliminary X-ray analysis of the pilus-associated sortase C from Streptococcus pneumoniae.

Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication

Crystal Structure of the HIV-2 Neutralizing Fab Fragment 7C8 with High Specificity to the V3 Region of gp125

Crystal structure of the dog lipocalin allergen Can f 2: implications for cross-reactivity to the cat allergen Fel d 4

Crystal structure of the major Malassezia sympodialis allergen Mala s 1 reveals a beta-propeller fold: a novel fold among allergens

Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity

Crystallization and preliminary crystallographic data of a Fel d 1 (1+2) construct corresponding to the major allergen from cat.

Crystallization and preliminary crystallographic study of the yeast Malassezia sympodialis allergen Mala s 1

Deletion of the V1/V2 region does not increase the accessibility of the V3 region of recombinant gp125

Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100

Designing a multimer allergen for diagnosis and immunotherapy of dog allergic patients

Detecting ligand interactions in real time on living bacterial cells.

Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.

Expression, refolding and crystallization of murine MHC class I H-2Db in complex with human beta2-microglobulin

Fine characterization of a V3-region neutralizing epitope in human immunodeficiency virus type 2.

Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis

Generation of neutralizing antibodies and divergence of SIVmac239 in cynomolgus macaques following short-term early antiretroviral therapy

Human cytomegalovirus-derived protein UL18 alters the phenotype and function of monocyte-derived dendritic cells

Immune modulation by the human cytomegalovirus-encoded molecule UL18, a mystery yet to be solved.

Increased sensitivity to broadly neutralizing antibodies of end-stage disease R5 HIV-1 correlates with evolution in Env glycosylation and charge

Inflammation-associated nitrotyrosination affects TCR recognition through reduced stability and alteration of the molecular surface of the MHC complex

LILRB1 polymorphisms influence posttransplant HCMV susceptibility and ligand interactions.

MHC class I recognition by NK receptors in the Ly49 family is strongly influenced by the beta 2-microglobulin subunit.

MICA-129 Dimorphism and Soluble MICA Are Associated With the Progression of Multiple Myeloma.

Malondialdehyde modification of myelin oligodendrocyte glycoprotein leads to increased immunogenicity and encephalitogenicity

Maternal MHC regulates generation of pathogenic antibodies and fetal MHC-encoded genes determine susceptibility in congenital heart block

Melanocortin 1 Receptor-derived peptides are efficiently recognized by cytotoxic T lymphocytes from melanoma patients

Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation.

Migratory activation of parasitized dendritic cells by the protozoan Toxoplasma gondii 14-3-3 protein

Multiple polymorphisms affect expression and function of the neuropeptide S receptor (NPSR1).

Murine class I major histocompatibility complex H–2Dd: expression, refolding and crystallization

Mutational analysis of amino acid residues involved in IgE-binding to the Malassezia sympodialis allergen Mala s 11

NK cell inhibitory receptor Ly-49C residues involved in MHC class I binding.

Natural killer cell tolerance persists despite significant reduction of self MHC class I on normal target cells in mice

Nitration of MOG diminishes its encephalitogenicity depending on MHC haplotype.

PD-1 expression on mouse intratumoral NK cells and its effects on NK cell phenotype

Peptide dependency and selectivity of the NK cell inhibitory receptor Ly-49C

Peptide-independent stabilization of MHC class I molecules breaches cellular quality control

Plasmodium falciparum rosetting epitopes converge in the SD3-loop of PfEMP1-DBL1α.

Primary HIV-1 R5 isolates from end-stage disease display enhanced viral fitness in parallel with increased gp120 net charge

Production, crystallization and preliminary X-ray diffraction analysis of the allergen Can f 2 from Canis familiaris.

Production, crystallization and preliminary crystallographic study of the major cat allergen Fel d 1.

Production, purification, crystallization and preliminary X-ray diffraction analysis of the HIV-2-neutralizing V3 loop-specific Fab fragment 7C8.

Proline substitution independently enhances H-2D(b) complex stabilization and TCR recognition of melanoma-associated peptides

PyTMs: a useful PyMOL plugin for modeling common post-translational modifications

SAMHD1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity

Spontaneous mutations in the human CMV HLA class I homologue UL18 affect its binding to the inhibitory receptor LIR-1/ILT2/CD85j

Structural Basis of the Differential Stability and Receptor Specificity of H-2Db in Complex with Murine versus Human β2-Microglobulin

Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of Streptococcus pneumoniae

Structural and functional studies of Spr1654: an essential aminotransferase in teichoic acid biosynthesis in Streptococcus pneumoniae.

Structural characterization of the tetrameric form of the major cat allergen Fel d 1

Structural elements underlying the high binding affinity of human cytomegalovirus UL18 to leukocyte immunoglobulin-like receptor-1

T Cell Tolerance Based on Avidity Thresholds Rather Than Complete Deletion Allows Maintenance of Maximal Repertoire Diversity

T-cell receptor-HLA-DRB1 associations suggest specific antigens in pulmonary sarcoidosis.

TAP-independent self-peptides enhance T cell recognition of immune-escaped tumors

The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation

The Immunogenicity of a Proline-Substituted Altered Peptide Ligand toward the Cancer-Associated TEIPP Neoepitope Trh4 Is Unrelated to Complex Stability.

The MHC Class I Cancer-Associated Neoepitope Trh4 Linked with Impaired Peptide Processing Induces a Unique Noncanonical TCR Conformer

The basic keratin 10-binding domain of the virulence-associated pneumococcal serine-rich protein PsrP adopts a novel MSCRAMM fold

The crystal structure of the major cat allergen Fel d 1, a member of the secretoglobin family

The crystal structure of the major pneumococcal autolysin LytA in complex with a large peptidoglycan fragment reveals the pivotal role of glycans for lytic activity

Three-Dimensional Structure of Fel d 1, the Major Allergen in Cat

Tuning antiviral CD8 T-cell response via proline-altered peptide ligand vaccination

Two crystal structures of pneumococcal pilus sortase C provide novel insights into catalysis and substrate specificity

Viral and cellular proteins containing FGDF motifs bind G3BP to block stress granule formation