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List of works by Milagros Medina

A laser flash absorption spectroscopy study of Anabaena sp. PCC 7119 flavodoxin photoreduction by photosystem I particles from spinach

scientific article published in November 1992

Arabidopsis FNRL protein is an NADPH-dependent chloroplast oxidoreductase resembling bacterial ferredoxin-NADP+ reductases

scientific article

Binding thermodynamics of ferredoxin:NADP+ reductase: two different protein substrates and one energetics

scientific article published on June 2009

CW-EPR and ENDOR study of cytochrome c6 from Anabaena PCC 7119.

scientific article published on 23 June 2006

Characterization of cytochrome c 6 from the cyanobacterium Anabaena PCC 7119

Coenzyme binding and hydride transfer in Rhodobacter capsulatus ferredoxin/flavodoxin NADP(H) oxidoreductase

scientific article

Crystal Structure of the FAD-Containing Ferredoxin-NADP+Reductase from the Plant PathogenXanthomonas axonopodispv. citri

scientific article

Crystallization and preliminary X-ray diffraction studies of FAD synthetase from Corynebacterium ammoniagenes

scientific article published on 27 November 2009

Crystals of Anabaena PCC 7119 ferredoxin-NADP+ reductase

scientific article published on 01 March 1991

Different phenotypic outcome due to site-specific phosphorylation in the cancer-associated NQO1 enzyme studied by phosphomimetic mutations

scientific article published in 2022

Direct examination of the relevance for folding, binding and electron transfer of a conserved protein folding intermediate.

scientific article published on 12 July 2017

Discovery of antimicrobial compounds targeting bacterial type FAD synthetases.

scientific article published in December 2018

Dual role of FMN in flavodoxin function: electron transfer cofactor and modulation of the protein-protein interaction surface

scientific article published on 10 November 2009

Electron spin echo envelope modulation studies of the semiquinone anion radical of cholesterol oxidase from Brevibacterium sterolicum

scientific article published on 01 January 1997

Electron transferases

scientific article published on January 2014

Evolutionary divergence of chloroplast FAD synthetase proteins ⬇️

scientific article published on October 18, 2010

Exact analysis of heterotropic interactions in proteins: Characterization of cooperative ligand binding by isothermal titration calorimetry

scientific article published on 9 June 2006

External loops at the ferredoxin-NADP(+) reductase protein-partner binding cavity contribute to substrates allocation

scientific article

Flavin photochemistry in the analysis of electron transfer reactions: role of charged and hydrophobic residues at the carboxyl terminus of ferredoxin-NADP(+) reductase in the interaction with its substrates

scientific article

Flavoproteins and flavoenzymes with biomedical and therapeutic impact

scientific article published on 01 January 2013

Histones cause aggregation and fusion of lipid vesicles containing phosphatidylinositol-4-phosphate

scientific article published on February 2015

Hyperfine correlation spectroscopy and electron spin echo envelope modulation spectroscopy study of the two coexisting forms of the hemeprotein cytochrome c6 from Anabaena Pcc7119.

scientific article published on January 2009

Identification of arginyl residues involved in the binding of ferredoxin-NADP+ reductase from Anabaena sp. PCC 7119 to its substrates

scientific article published on 01 December 1992

In silico discovery and biological validation of ligands of FAD synthase, a promising new antimicrobial target

scientific article published on 14 August 2020

Insights into the FMNAT Active Site of FAD Synthase: Aromaticity is Essential for Flavin Binding and Catalysis ⬇️

scientific article published on 25 May 2020

Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration

scientific article

Key residues at the riboflavin kinase catalytic site of the bifunctional riboflavin kinase/FMN adenylyltransferase from Corynebacterium ammoniagenes

scientific article

Kinetic and chemical characterization of aldehyde oxidation by fungal aryl-alcohol oxidase

scientific article published on 15 January 2010

Kinetics and thermodynamics of the protein-ligand interactions in the riboflavin kinase activity of the FAD synthetase from Corynebacterium ammoniagenes

scientific article published on 4 August 2017

Lysine residues on ferredoxin-NADP+ reductase from Anabaena sp. PCC 7119 involved in substrate binding

scientific article published on 01 February 1992

Mechanism of coenzyme recognition and binding revealed by crystal structure analysis of ferredoxin-NADP+ reductase complexed with NADP+

scientific article

Multiple implications of an active site phenylalanine in the catalysis of aryl-alcohol oxidase.

scientific article

Mutation of Aspartate 238 in FAD Synthase Isoform 6 Increases the Specific Activity by Weakening the FAD Binding ⬇️

scientific article published on 09 December 2019

Oligomeric state in the crystal structure of modular FAD synthetase provides insights into its sequential catalysis in prokaryotes

scientific article

Protein dynamics promote hydride tunnelling in substrate oxidation by aryl-alcohol oxidase

scientific article published on 18 October 2017

Protein motifs involved in coenzyme interaction and enzymatic efficiency in anabaena ferredoxin-NADP+ reductase

scientific article

Protein-protein interaction in electron transfer reactions: the ferredoxin/flavodoxin/ferredoxin:NADP+ reductase system from Anabaena

scientific article published on 01 October 1998

Quaternary organization in a bifunctional prokaryotic FAD synthetase: Involvement of an arginine at its adenylyltransferase module on the riboflavin kinase activity

scientific article

Role of key residues at the flavin mononucleotide (FMN):adenylyltransferase catalytic site of the bifunctional riboflavin kinase/flavin adenine dinucleotide (FAD) Synthetase from Corynebacterium ammoniagenes

scientific article published on 8 November 2012

Role of specific residues in coenzyme binding, charge-transfer complex formation, and catalysis in Anabaena ferredoxin NADP+-reductase

scientific article

Specific Features for the Competent Binding of Substrates at the FMN Adenylyltransferase Site of FAD Synthase from Corynebacterium ammoniagenes

scientific article published on 14 October 2019

Spectral and catalytic properties of aryl-alcohol oxidase, a fungal flavoenzyme acting on polyunsaturated alcohols.

scientific article published on August 2005

Structural analysis of FAD synthetase from Corynebacterium ammoniagenes

scientific article

Structural and magnetic characterisation of the haem core of ferricytochromes c 6

Structural backgrounds for the formation of a catalytically competent complex with NADP(H) during hydride transfer in ferredoxin-NADP(+) reductases

scientific article

Structural basis of the catalytic role of Glu301 inAnabaena PCC 7119 ferredoxin-NADP+ reductase revealed by x-ray crystallography

Structural insights into the synthesis of FMN in prokaryotic organisms

scientific article

Structure-function relationships in Anabaena ferredoxin/ferredoxin:NADP(+) reductase electron transfer: insights from site-directed mutagenesis, transient absorption spectroscopy and X-ray crystallography

scientific article

Studying the Allosteric Energy Cycle by Isothermal Titration Calorimetry

scientific article published on 01 January 2012

Substrate diffusion and oxidation in GMC oxidoreductases: an experimental and computational study on fungal aryl-alcohol oxidase.

scientific article

The C-terminal extension of bacterial flavodoxin-reductases: involvement in the hydride transfer mechanism from the coenzyme

scientific article

The Catalytic Cycle of the Antioxidant and Cancer-Associated Human NQO1 Enzyme: Hydride Transfer, Conformational Dynamics and Functional Cooperativity

scientific article published on 20 August 2020

The FAD synthetase from the human pathogen Streptococcus pneumoniae: a bifunctional enzyme exhibiting activity-dependent redox requirements.

scientific article

The RFK catalytic cycle of the pathogen Streptococcus pneumoniae shows species-specific features in prokaryotic FMN synthesis

scientific article

The apoptosis-inducing factor family: Moonlighting proteins in the crosstalk between mitochondria and nuclei

scientific article published on 09 October 2020

The ferredoxin-NADP(H) reductase from Rhodobacter capsulatus: molecular structure and catalytic mechanism

scientific article published in September 2005

The oxido-reductase activity of the apoptosis inducing factor: a promising pharmacological tool?

scientific article published on January 2013

The prokaryotic FAD synthetase family: a potential drug target

scientific article

The puzzle of ligand binding to Corynebacterium ammoniagenes FAD synthetase

scientific article

The trimer interface in the quaternary structure of the bifunctional prokaryotic FAD synthetase from Corynebacterium ammoniagenes

scientific article published on 24 March 2017

Theoretical Analysis of the Electron Spin Density Distribution of the Flavin Semiquinone Isoalloxazine Ring within Model Protein Environments

Theoretical Study of the Mechanism of the Hydride Transfer between Ferredoxin–NADP+ Reductase and NADP+: The Role of Tyr303

scientific article published in 2012

Unexpected diversity of ferredoxin-dependent thioredoxin reductases in cyanobacteria

scientific article published on 01 May 2021

W196 and the <i>β</i>-Hairpin Motif Modulate the Redox Switch of Conformation and the Biomolecular Interaction Network of the Apoptosis-Inducing Factor

scientific article published on 15 January 2021

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