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List of works by Fernando González-Candelas

A Bayesian approach for discriminating among alternative inheritance hypotheses in plant polyploids: the allotetraploid origin of genus Borderea (Dioscoreaceae)

scientific article

A method for determining the position and size of optimal sequence regions for phylogenetic analysis.

scientific article published in December 1995

A new subtype of hepatitis C virus genotype 1: complete genome and phylogenetic relationships of an Equatorial Guinea isolate.

scientific article published in June 2006

A novel approach to identify candidate prognostic factors for hepatitis C treatment response integrating clinical and viral genetic data.

scientific article published on 23 February 2015

A20 Sample preparation for whole-genome next-generation sequencing (NGS) of hepatitis C virus (HCV) routine RNA samples

An 18S rDNA-based molecular phylogeny of aphidiinae (Hymenoptera: braconidae)

scientific article published on 01 February 2000

An unusually high substitution rate in transplant-associated BK polyomavirus in vivo is further concentrated in HLA-C-bound viral peptides

scientific article published on 18 October 2018

Analysis of population genetic structure and variability using RAPD markers in the endemic and endangered Limonium dufourii (Plumbaginaceae).

scientific article published in December 1997

Analysis of the overdispersed clock in the short-term evolution of hepatitis C virus: Using the E1/E2 gene sequences to infer infection dates in a single source outbreak

scientific article published on 3 April 2006

Antibiotics as selectors and accelerators of diversity in the mechanisms of resistance: from the resistome to genetic plasticity in the β-lactamases world

scientific article published on 8 February 2013

Assessing the potential association between SARS-CoV-2 RNA load in the respiratory tract and COVID-19 mortality

scientific article published on 02 November 2020

Bacterial and Eukaryotic Phosphoketolases: Phylogeny, Distribution and Evolution

scientific article published on 06 January 2010

Baseline prediction of combination therapy outcome in hepatitis C virus 1b infected patients by discriminant analysis using viral and host factors

scientific article

Benefit of conjugate pneumococcal vaccination in preventing influenza hospitalization in children: a case-control study.

scientific article

Characterization of New Recombinant Forms of HIV-1 From the Comunitat Valenciana (Spain) by Phylogenetic Incongruence.

scientific article published on 22 May 2019

Characterization of seven (CTT)(n) microsatellite loci in the Pyrenean endemic Borderea pyrenaica (Dioscoreaceae): remarks on ploidy level and hybrid origin assessed through allozymes and microsatellite analyses.

scientific article published in March 2004

Combined therapy of interferon plus ribavirin promotes multiple adaptive solutions in hepatitis C virus.

scientific article published on April 2009

Common gene expression strategies revealed by genome-wide analysis in yeast.

scientific article published on January 2007

Comparative analysis of variation and selection in the HCV genome

scientific article

Comparative genomic and phylogenetic analyses of Gammaproteobacterial glg genes traced the origin of the Escherichia coli glycogen glgBXCAP operon to the last common ancestor of the sister orders Enterobacteriales and Pasteurellales.

scientific article published on 21 January 2015

Comparison of body mass index (BMI) with the CUN-BAE body adiposity estimator in the prediction of hypertension and type 2 diabetes.

scientific article published on 27 January 2016

Comparison of clinical and environmental samples of Legionella pneumophila at the nucleotide sequence level

scientific article published on 22 May 2009

Complete Analysis of the Epidemiological Scenario around a SARS-CoV-2 Reinfection: Previous Infection Events and Subsequent Transmission

scientific article published on 08 September 2021

Complete genome of a European hepatitis C virus subtype 1g isolate: phylogenetic and genetic analyses

scientific article

Comprehensive Screening for Naturally Occurring Hepatitis C Virus Resistance to Direct-Acting Antivirals in the NS3, NS5A, and NS5B Genes in Worldwide Isolates of Viral Genotypes 1 to 6

scientific article published on 8 February 2016

Computational models of liver fibrosis progression for hepatitis C virus chronic infection.

scientific article

Contribution of insertions and deletions to the variability of hepatitis C virus populations.

scientific article published in August 2007

Correction: No Major Host Genetic Risk Factor Contributed to A(H1N1)2009 Influenza Severity.

scientific article published on 30 October 2015

DISTANCE: a program to calculate distances and other parameters of an alignment of DNA sequences

scientific article published on 01 January 1994

Detecting Changes in the Functional Constraints of Paralogous Genes

article

Different prognosis in hospitalized patients with influenza one season after the pandemic H1N1 influenza of 2009-2010 in Spain.

scientific article

Direct sequencing of Legionella pneumophila from respiratory samples for sequence-based typing analysis

scientific article published on 15 July 2009

Does the VP1 gene of foot-and-mouth disease virus behave as a molecular clock?

scientific article

Domain organization and evolution of multifunctional autoprocessing repeats-in-toxin (MARTX) toxin in Vibrio vulnificus.

scientific article published on 12 November 2010

Effect of Occupational Exposure on A(H1N1)pdm09 Infection and Hospitalization.

scientific article

Effect of Ribavirin on the Mutation Rate and Spectrum of Hepatitis C Virus In Vivo

scientific article (publication date: June 2009)

Effect of antiviral treatment and host susceptibility on positive selection in hepatitis C virus (HCV).

scientific article published on 5 November 2007

Effect of oligonucleotide primers in determining viral variability within hosts

scientific article

Effectiveness of hand hygiene and provision of information in preventing influenza cases requiring hospitalization

scientific article published on 23 April 2012

Effectiveness of pandemic and seasonal influenza vaccines in preventing pandemic influenza-associated hospitalization

scientific article

Effectiveness of vaccination with 23-valent pneumococcal polysaccharide vaccine in preventing hospitalization with laboratory confirmed influenza during the 2009-2010 and 2010-2011 seasons.

scientific article

Emergence and spread of a SARS-CoV-2 variant through Europe in the summer of 2020

scientific article published on 27 November 2020

Emerging trends in CRF02_AG variants transmission among men who have sex with men in Spain.

scientific article published in March 2014

Enterovirus co-infections and onychomadesis after hand, foot, and mouth disease, Spain, 2008.

scientific article published in December 2011

Epidemic dynamics of two coexisting hepatitis C virus subtypes

scientific article published in January 2007

Epidemiology and molecular investigation of hepatitis C infection following holiday haemodialysis.

scientific article published on 28 September 2012

EvalMSA: A Program to Evaluate Multiple Sequence Alignments and Detect Outliers.

scientific article

Evidence of Recombination in Intrapatient Populations of Hepatitis C Virus

scientific article

Evolution of arginine deiminase (ADI) pathway genes.

scientific article

Evolution of snake venom disintegrins by positive Darwinian selection

scientific article

Evolutionary analysis of genetic variation observed in citrus tristeza virus (CTV) after host passage.

scientific article

Evolutionary and Phenotypic Characterization of Two Spike Mutations in European Lineage 20E of SARS-CoV-2

scientific article published on 16 November 2021

Evolutionary dynamics of the E1-E2 viral populations during combination therapy in non-responder patients chronically infected with hepatitis C virus subtype 1b.

scientific article published on 26 September 2012

Evolutionary history of the OmpR/IIIA family of signal transduction two component systems in Lactobacillaceae and Leuconostocaceae.

scientific article

Evolutionary trajectories of beta-lactamase CTX-M-1 cluster enzymes: predicting antibiotic resistance

scientific article

Expansion of the CRF19_cpx Variant in Spain

scientific article published on 23 June 2015

Fitness alteration of foot-and-mouth disease virus mutants: measurement of adaptability of viral quasispecies.

scientific article

From phylogenetics to phylogenomics: the evolutionary relationships of insect endosymbiotic gamma-Proteobacteria as a test case.

scientific article published in February 2007

Gene expression models based on a reference laboratory strain are bad predictors of Mycobacterium tuberculosis complex transcriptional diversity

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Gene expression models based on a reference laboratory strain are poor predictors of Mycobacterium tuberculosis complex transcriptional diversity.

scientific article published on 28 February 2018

Gene flow rates in Yugoslavian populations of the smooth newt Triturus vulgaris

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Generalized Linear Model (GLM) framework for the association of host variables and viral strains with liver fibrosis in HCV/HIV coinfected patients.

scientific article published on 19 November 2012

Genetic Characterization of Legionella pneumophila Isolated from a Common Watershed in Comunidad Valenciana, Spain

scientific article

Genetic Variability of Hepatitis C Virus before and after Combined Therapy of Interferon plus Ribavirin

scientific article (publication date: 26 August 2008)

Genetic similarity of hepatitis C virus and fibrosis progression in chronic and recurrent infection after liver transplantation.

scientific article published in February 2006

Genetic variability in environmental isolates of Legionella pneumophila from Comunidad Valenciana (Spain).

scientific article published in June 2006

Genetic variability in hepatitis C virus and its role in antiviral treatment response.

scientific article published in March 2008

Genetic variability of hepatitis C virus non-structural protein 3 and virus-specific CD8+ response in patients with chronic hepatitis C.

scientific article published on April 2004

Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex

scientific article published on 05 September 2019

Genomic Investigation of a Legionellosis Outbreak in a Persistently Colonized Hotel

scientific article

Genomic determinants of speciation and spread of the Mycobacterium tuberculosis complex

scientific article published on 12 June 2019

Genotypes and subgenotypes of hepatitis B virus circulating in an endemic area in Peru

scientific article published on 25 September 2017

Geographical and Temporal Structures of Legionella pneumophila Sequence Types in Comunitat Valenciana (Spain), 1998 to 2013.

scientific article

Hepatitis C virus and the controversial role of the interferon sensitivity determining region in the response to interferon treatment.

scientific article published in February 2008

Hepatitis C virus sequences from different patients confirm the existence and transmissibility of subtype 2q, a rare subtype circulating in the metropolitan area of Barcelona, Spain

scientific article published in May 2011

High Body Mass Index as a Risk Factor for Hospitalization Due to Influenza: A Case-Control Study.

scientific article

High-throughput sequencing (HTS) for the analysis of viral populations

scientific article published on 27 January 2020

Historical and biological determinants of genetic diversity in the highly endemic triploid sea lavender Limonium dufourii (Plumbaginaceae)

scientific article published on 01 September 2007

Horizontal gene transfer in the molecular evolution of mannose PTS transporters.

scientific article published in August 2005

Identification of a large, fast-expanding HIV-1 subtype B transmission cluster among MSM in Valencia, Spain.

scientific article

Influenza Vaccine Effectiveness in Preventing Outpatient, Inpatient, and Severe Cases of Laboratory-Confirmed Influenza

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Influenza vaccination of primary healthcare physicians may be associated with vaccination in their patients: a vaccination coverage study

scientific article

Isolation and Characterization of Two Klebsiella pneumoniae Phages Encoding Divergent Depolymerases

scientific article published on 30 April 2020

Isolation of Four Lytic Phages Infecting Klebsiella pneumoniae K22 Clinical Isolates from Spain

scientific article published on 09 January 2020

Knowledge of and attitudes to influenza in unvaccinated primary care physicians and nurses.

scientific article published on January 2014

Knowledge of and attitudes to influenza vaccination in healthy primary healthcare workers in Spain, 2011-2012

scientific article

Legionellosis outbreak associated with asphalt paving machine, Spain, 2009.

scientific article published on September 2010

MICROSATELIGHT--pipeline to expedite microsatellite analysis.

scientific article published on 2 December 2010

Managing an online survey about influenza vaccination in primary healthcare workers.

scientific article

Mixed infection by Legionella pneumophila in outbreak patients.

scientific article published on 14 November 2013

Molecular characterization of Treponema pallidum subsp. pallidum in Switzerland and France with a new multilocus sequence typing scheme

scientific article published in PLoS ONE

Molecular diversity and evolutionary processes of Alternaria solani in Brazil inferred using genealogical and coalescent approaches

scientific article published on June 2009

Molecular epidemiology and evolution in an outbreak of fulminant hepatitis B virus.

scientific article published on April 2006

Molecular epidemiology and forensic genetics: application to a hepatitis C virus transmission event at a hemodialysis unit.

scientific article published on 8 January 2003

Molecular epidemiology of HIV-1 subtype B in the Basque Country (Spain).

scientific article published on 25 May 2012

Molecular epidemiology of a hepatitis C virus outbreak in a hemodialysis unit

scientific article

Molecular epidemiology studies on the immigrant population in Spain

scientific article published on November 2014

Molecular evolution in court: analysis of a large hepatitis C virus outbreak from an evolving source

scientific article published on July 19, 2013

Molecular surveillance of HIV-1 in Madrid, Spain: a phylogeographic analysis.

scientific article

Multiple methods for the identification of polymorphic simple sequence repeats (SSRs) in sorghum [Sorghum bicolor (L.) Moench].

scientific article

No Major Host Genetic Risk Factor Contributed to A(H1N1)2009 Influenza Severity

scientific article

On the analysis of viability data: an example with Drosophila.

scientific article

One is not enough: On the effects of reference genome for the mapping and subsequent analyses of short-reads

scientific article published on 27 January 2021

Onychomadesis outbreak in Valencia, Spain associated with hand, foot, and mouth disease caused by enteroviruses.

scientific article

Origin and phylogeography of the Chagas disease main vector Triatoma infestans based on nuclear rDNA sequences and genome size.

scientific article published on 20 April 2005

Origin of modern syphilis and emergence of a contemporary pandemic cluster

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Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster

scientific article

Overlapping of Independent SARS-CoV-2 Nosocomial Transmissions in a Complex Outbreak

scientific article published on 04 August 2021

Pandemic influenza A (H1N1) in non-vaccinated, pregnant women in Spain (2009-2010).

scientific article

Pandemic influenza A (H1N1) infection in pregnant and nonpregnant women in Spain (2009-2010).

scientific article

Patient-to-patient transmission of hepatitis C virus (HCV) during colonoscopy diagnosis.

scientific article published on 8 September 2010

Phylogenetic analysis of an epidemic outbreak of acute hepatitis C in HIV-infected patients by ultra-deep pyrosequencing.

scientific article published on 10 May 2017

Phylogenetic analysis of environmental Legionella pneumophila isolates from an endemic area (Alcoy, Spain).

scientific article published on 13 December 2014

Phylogenetic signal and functional categories in Proteobacteria genomes

scientific article

Phylogeny of Vibrio vulnificus from the Analysis of the Core-Genome: Implications for Intra-Species Taxonomy

scientific article published in January 2017

Phylogeography and genetic variation of Triatoma dimidiata, the main Chagas disease vector in Central America, and its position within the genus Triatoma

scientific article

Polyphyletic origin of Vibrio vulnificus biotype 2 as revealed by sequence-based analysis.

scientific article published on 19 November 2010

Polyploid origin, genetic diversity and population structure in the tetraploid sea lavender Limonium narbonense Miller (Plumbaginaceae) from eastern Spain.

scientific article

Population structure and recombination in environmental isolates of Legionella pneumophila.

scientific article published in March 2007

Postmating Isolation Analysis in Founder-Flush Experimental Populations of Drosophila pseudoobscura

Postsymbiotic plasmid acquisition and evolution of the repA1-replicon in Buchnera aphidicola.

scientific article published on September 2000

Predictive factors of severe multilobar pneumonia and shock in patients with influenza.

scientific article

Prephenate dehydratase from the aphid endosymbiont (Buchnera) displays changes in the regulatory domain that suggest its desensitization to inhibition by phenylalanine.

scientific article published on May 2000

Prognosis of hospitalized patients with 2009 H1N1 influenza in Spain: influence of neuraminidase inhibitors.

scientific article

Quantifying nonvertical inheritance in the evolution of Legionella pneumophila.

scientific article published on 20 October 2010

Reanalysis of Chinese Treponema pallidum samples: all Chinese samples cluster with SS14-like group of syphilis-causing treponemes.

scientific article

Recombination drives genome evolution in outbreak-related Legionella pneumophila isolates.

scientific article

Recombination in Hepatitis C Virus

scientific article published on October 24, 2011

Recombination in viruses: mechanisms, methods of study, and evolutionary consequences.

scientific article published on 23 December 2014

Refined analysis of genetic variability parameters in hepatitis C virus and the ability to predict antiviral treatment response.

scientific article published on 4 May 2008

Relating the outcome of HCV infection and different host SNP polymorphisms in a Majorcan population coinfected with HCV-HIV and treated with pegIFN-RBV.

scientific article published on March 2014

Relationship between density- and frequency-dependent effects in two strains of Drosophila melanogaster

scientific article published on January 1988

Ribotyping of vibrio populations associated with cultured oysters (Ostrea edulis)

scientific article published on 01 October 2000

Risk factors and effectiveness of preventive measures against influenza in the community

scientific article published on 27 March 2012

SARS-CoV-2 and COVID-19: A genetic, epidemiological, and evolutionary perspective

scientific article published on 28 May 2020

Sampling and repeatability in the evaluation of hepatitis C virus genetic variability.

scientific article published in September 2003

Score to identify the severity of adult patients with influenza A (H1N1) 2009 virus infection at hospital admission.

scientific article published on 24 April 2012

Smoking may increase the risk of hospitalization due to influenza.

scientific article published on 16 April 2016

Social class based on occupation is associated with hospitalization for A(H1N1)pdm09 infection. Comparison between hospitalized and ambulatory cases.

scientific article

Sociodemographic factors and clinical conditions associated to hospitalization in influenza A (H1N1) 2009 virus infected patients in Spain, 2009-2010.

scientific article

Staphylococcus prevails in the skin microbiota of long-term immunodeficient mice.

scientific article

Study of the evolutionary relationships among Limonium species (Plumbaginaceae) using nuclear and cytoplasmic molecular markers

scientific article published on 01 February 2000

The Evolutionary Origin of Xanthomonadales Genomes and the Nature of the Horizontal Gene Transfer Process

article

The International Virus Bioinformatics Meeting 2022

publication published on 05 May 2022

The USH2A c.2299delG mutation: dating its common origin in a Southern European population

scientific article

The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variant

scientific article published on 30 September 2021

The genome sequence of Blochmannia floridanus: comparative analysis of reduced genomes

scientific article

The impact of virus population diversity on the dynamics of cytomegalovirus DNAemia in allogeneic stem cell transplant recipients.

scientific article published on 6 September 2017

The molecular epidemiology of HIV-1 in the Comunidad Valenciana (Spain): analysis of transmission clusters.

scientific article published on 14 September 2017

The population genetics and evolutionary epidemiology of RNA viruses

scientific article published on April 2004

The power and limitations of genomic surveillance of bacteria

scientific article published on 01 November 2019

The role of positive selection in hepatitis C virus

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Time and rate of evolution are the key to establish transmission cases

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Topology testing of phylogenies using least squares methods

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Transmission dynamics of HIV-1 subtype B in the Basque Country, Spain.

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Transmission of human immunodeficiency virus Type-1 by fresh-frozen plasma treated with methylene blue and light.

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Trends in influenza vaccine coverage among primary healthcare workers in Spain, 2008-2011.

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Ultradeep sequencing analysis of population dynamics of virus escape mutants in RNAi-mediated resistant plants

scientific article published on 15 May 2012

Unequal distribution of RT-PCR artifacts along the E1-E2 region of Hepatitis C virus

scientific article published on 11 June 2009

Unraveling the evolutionary history of the phosphoryl-transfer chain of the phosphoenolpyruvate:phosphotransferase system through phylogenetic analyses and genome context.

scientific article

Using evolutionary tools to refine the new hypervariable region 3 within the envelope 2 protein of hepatitis C virus.

scientific article published on 25 October 2007

Validating viral quasispecies with digital organisms: a re-examination of the critical mutation rate

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Visualizing knowledge and attitude factors related to influenza vaccination of physicians.

scientific article published on 19 December 2014

Whole genome sequencing analysis of intrapatient microevolution in Mycobacterium tuberculosis: potential impact on the inference of tuberculosis transmission.

scientific article

Whole-genome sequencing of Neisseria gonorrhoeae in a forensic transmission case

scientific article published on 08 July 2019

[Risk factors of influenza (H1N1) 2009 hospitalization and effectiveness of pharmaceutical and nonpharmaceutical interventions in its prevention: a case-control study].

scientific article

epiPATH: an information system for the storage and management of molecular epidemiology data from infectious pathogens.

scientific article