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List of works by Howard Riezman

1-Deoxydihydroceramide causes anoxic death by impairing chaperonin-mediated protein folding

scientific article published on 14 October 2019

A 70-kd protein of the yeast mitochondrial outer membrane is targeted and anchored via its extreme amino terminus

scientific article

A Chemogenetic Approach for the Optical Monitoring of Voltage in Neurons

scientific article published on 25 January 2019

A fluorogenic probe for SNAP-tagged plasma membrane proteins based on the solvatochromic molecule Nile Red.

scientific article published on 29 January 2014

A glycosylphosphatidylinositol-anchoring inhibitor with an unusual tetracarbocyclic sesterterpene skeleton from the fungus Codinaea simplex

A major 125-kd membrane glycoprotein of Saccharomyces cerevisiae is attached to the lipid bilayer through an inositol-containing phospholipid

scientific article

A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance

article

A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis

scientific article

A yeast t-SNARE involved in endocytosis

scientific article published on October 1998

Actin-, myosin- and ubiquitin-dependent endocytosis.

scientific article

Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells

scientific article published on 30 December 2011

Alpha-COP can discriminate between distinct, functional di-lysine signals in vitro and regulates access into retrograde transport

scientific article published on 01 December 1998

Amphiphilic dynamic NDI and PDI probes: imaging microdomains in giant unilamellar vesicles

An efficient method for the production of isotopically enriched cholesterol for NMR

scientific article

An essential function of sphingolipids in yeast cell division

scientific article

An intact SH3 domain is required for myosin I-induced actin polymerization.

scientific article

Analysis of the sequence requirements for glycosylphosphatidylinositol anchoring of Saccharomyces cerevisiae Gas1 protein

scientific article published in Journal of Biological Chemistry

Author Correction: Understanding the diversity of membrane lipid composition

scientific article published on 01 November 2019

Autophagy competes for a common phosphatidylethanolamine pool with major cellular PE-consuming pathways in Saccharomyces cerevisiae

scientific article

Binding of precursors of cytoplasmically-synthesized mitochondrial proteins to isolated outer membranes of yeast mitochondria

scientific article published on 01 January 1982

Biosynthesis and trafficking of sphingolipids in the yeast Saccharomyces cerevisiae

scientific article

Biosynthesis of the Torpedo californica acetylcholine receptor alpha subunit in yeast

scientific article published in Science

COPII Coat Composition Is Actively Regulated by Luminal Cargo Maturation

article

Calcium-independent calmodulin requirement for endocytosis in yeast

scientific article

Cell biology: the ubiquitin connection.

scientific article

Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviour

scientific article published on 25 May 2015

Ceramide chain length-dependent protein sorting into selective endoplasmic reticulum exit sites

scientific article published on 11 December 2020

Ceramide synthesis enhances transport of GPI-anchored proteins to the Golgi apparatus in yeast.

scientific article

Chapter 12 Biogenesis of energy-transducing systems

Chapter 13 Transport of GPI‐Anchored Proteins

article published in 2009

Characterization of the END1 gene required for vacuole biogenesis and gluconeogenic growth of budding yeast

scientific article

Chemical biology approaches to membrane homeostasis and function

scientific article published on January 2011

Clathrin functions in the absence of heterotetrameric adaptors and AP180-related proteins in yeast

scientific article published on July 1999

Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum

scientific article

Concentration of GPI-anchored proteins upon ER exit in yeast

scientific article published on 20 November 2008

Conceptually new entries into cells

scientific article

Conformational changes in the Arp2/3 complex leading to actin nucleation

scientific article published on 12 December 2004

Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei

scientific article published on September 2000

Cytoplasmic tail phosphorylation of the alpha-factor receptor is required for its ubiquitination and internalization

scientific article

Cytotoxicity of 1-deoxysphingolipid unraveled by genome-wide genetic screens and lipidomics in Saccharomyces cerevisiae

scientific article published on 11 September 2019

D38-cholesterol as a Raman active probe for imaging intracellular cholesterol storage

scientific article

Detection of an intermediate compartment involved in transport of alpha-factor from the plasma membrane to the vacuole in yeast

scientific article

Detection of genome-edited mutant clones by a simple competition-based PCR method

scientific article

Determinants for glycophospholipid anchoring of the Saccharomyces cerevisiae GAS1 protein to the plasma membrane ⬇️

scientific article published on January 1, 1991

Deuterated Cholesterol Uptake Revealed With Stimulated Raman Microscopy

article published in 2015

Differential ER exit in yeast and mammalian cells

scientific article published in August 2004

Disruption of the ceramide synthase LOH1 causes spontaneous cell death in Arabidopsis thaliana

scientific article published on 22 August 2011

Distinct acto/myosin-I structures associate with endocytic profiles at the plasma membrane.

scientific article published on 17 March 2008

Distinct functions of calmodulin are required for the uptake step of receptor-mediated endocytosis in yeast: the type I myosin Myo5p is one of the calmodulin targets

scientific article

Distribution and functions of sterols and sphingolipids

scientific article published in May 2011

Down regulation of yeast G protein-coupled receptors ⬇️

scientific article published on April 1, 1998

Drs2p-related P-type ATPases Dnf1p and Dnf2p are required for phospholipid translocation across the yeast plasma membrane and serve a role in endocytosis

scientific article

Dynamic amphiphile libraries to screen for the "fragrant" delivery of siRNA into HeLa cells and human primary fibroblasts

scientific article

End13p/Vps4p is required for efficient transport from early to late endosomes in Saccharomyces cerevisiae.

scientific article published in May 2001

End4p/Sla2p interacts with actin-associated proteins for endocytosis in Saccharomyces cerevisiae.

scientific article published on November 1997

Endocytic internalization in yeast and animal cells: similar and different

scientific article

Endocytosis in yeast

Endocytosis in yeast: Several of the yeast secretory mutants are defective in endocytosis

scientific article published on 01 April 1985

Endocytosis is required for the growth of vacuolar H(+)-ATPase-defective yeast: identification of six new END genes

scientific article

Expression of Mycobacterium leprae 18-kDa antigen in yeast in a GPI-anchored form

scientific article published on 01 March 1994

Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology

scientific article published on 18 February 2009

Functional interactions between the p35 subunit of the Arp2/3 complex and calmodulin in yeast

scientific article

Gaa1p and gpi8p are components of a glycosylphosphatidylinositol (GPI) transamidase that mediates attachment of GPI to proteins

scientific article

Genetic and biochemical interactions between the Arp2/3 complex, Cmd1p, casein kinase II, and Tub4p in yeast

scientific article

Glycosylphosphatidylinositol

article

Glycosylphosphatidylinositol anchors regulate glycosphingolipid levels

scientific article published on 24 May 2012

HCV 3a core protein increases lipid droplet cholesteryl ester content via a mechanism dependent on sphingolipid biosynthesis

scientific article

History of Biochemistry at the University of Geneva From the Boulevard des Philosophes to Quai Ernest-Ansermet

scientific article published in December 2009

Identification and Mode of Action of a Plant Natural Product Targeting Human Fungal Pathogens.

scientific article published on 3 July 2017

Identification and characterization of Saccharomyces cerevisiae mutants defective in fluid-phase endocytosis.

scientific article

Identification of a novel sequence mediating regulated endocytosis of the G protein-coupled alpha-pheromone receptor in yeast

scientific article

Identification of a species-specific inhibitor of glycosylphosphatidylinositol synthesis

scientific article

Identifying key residues of sphinganine-1-phosphate lyase for function in vivo and in vitro

scientific article

Immunolocalization of glyceraldehyde-3-phosphate dehydrogenase, hexokinase, and carboxypeptidase Y in yeast cells at the ultrastructural level

scientific article published in March 1987

Import of proteins into mitochondria: a 70 kilodalton outer membrane protein with a large carboxy-terminal deletion is still transported to the outer membrane.

scientific article

Import of proteins into mitochondria: nucleotide sequence of the gene for a 70-kd protein of the yeast mitochondrial outer membrane

scientific article

Increased protein kinase or decreased PP2A activity bypasses sphingoid base requirement in endocytosis

scientific article

Increased ubiquitin-dependent degradation can replace the essential requirement for heat shock protein induction

scientific article

Interdependence of filamentous actin and microtubules for asymmetric cell division

scientific article

Intracellular sphingosine releases calcium from lysosomes

scientific article published on 27 November 2015

Intracellular transport of GPI-anchored proteins

scientific article

Intracellular transport of GPI-anchored proteins by yeast

scientific article published on 01 February 1994

Involvement of Ypt7p, a small GTPase, in traffic from late endosome to the vacuole in yeast

scientific article published on 01 November 1993

Isolation, characterization and regulation of expression of the nuclear genes for the core II and Rieske iron-sulphur proteins of the yeast ubiquinol-cytochrome c reductase

article

LAPTM4B facilitates late endosomal ceramide export to control cell death pathways.

scientific article published on 17 August 2015

Lag1p and Lac1p are essential for the Acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisae

scientific article

Lcb4p is a key regulator of ceramide synthesis from exogenous long chain sphingoid base in Saccharomyces cerevisiae

scientific article

Limited ER quality control for GPI-anchored proteins.

scientific article

Linking cargo to vesicle formation: receptor tail interactions with coat proteins.

scientific article published on August 1997

Lip1p: a novel subunit of acyl-CoA ceramide synthase

scientific article

Lipid pickup and delivery

Lipidomic profiling of Saccharomyces cerevisiae and Zygosaccharomyces bailii reveals critical changes in lipid composition in response to acetic acid stress

scientific article

Lipidomics reveals diurnal lipid oscillations in human skeletal muscle persisting in cellular myotubes cultured in vitro.

scientific article published on 25 September 2017

Loss of ceramide synthase 3 causes lethal skin barrier disruption

scientific article

Luciferase-Induced Photouncaging: Bioluminolysis

scientific article published on 20 September 2019

Lysosome-targeted photoactivation reveals local sphingosine metabolism signatures

scientific article published on 26 December 2018

Macrophages release plasma membrane-derived particles rich in accessible cholesterol

scientific article published on 20 August 2018

Making Sense of the Yeast Sphingolipid Pathway

scientific article published on 21 September 2016

Mathematical modeling and validation of the ergosterol pathway in Saccharomyces cerevisiae

scientific article

Membrane Phosphoproteomics of Yeast Early Response to Acetic Acid: Role of Hrk1 Kinase and Lipid Biosynthetic Pathways, in Particular Sphingolipids

scientific article published on 12 July 2017

Methylation of the sterol nucleus by STRM-1 regulates dauer larva formation in Caenorhabditis elegans.

scientific article

Mitochondria-specific photoactivation to monitor local sphingosine metabolism and function

scientific article

Mitochondrial arginase-2 is a cell‑autonomous regulator of CD8+ T cell function and antitumor efficacy

scientific article published on 21 November 2019

Mitochondrial disruption in peroxisome deficient cells is hepatocyte selective but is not mediated by common hepatic peroxisomal metabolites

scientific article published on 30 August 2017

Molecular mechanisms of endocytosis

scientific article published on December 1997

Morphology of the yeast endocytic pathway

scientific article published on January 1998

Multiple functions of sterols in yeast endocytosis

scientific article

Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency

scientific article published on 06 February 2017

NCCR Chemical Biology: Interdisciplinary Research Excellence, Outreach, Education, and New Tools for Switzerland.

scientific article published in January 2011

Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane

scientific article published on 29 December 2007

On the road to unraveling the molecular functions of ether lipids

scientific article published on 13 June 2019

Optical control of sphingosine-1-phosphate formation and function

scientific article published on 29 April 2019

Ordering of compartments in the yeast endocytic pathway

scientific article

Organization and functions of sphingolipid biosynthesis in yeast

scientific article

Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast.

scientific article

Partial purification and characterization of early and late endosomes from yeast. Identification of four novel proteins.

scientific article

Patches and Blebs: A Comparative Study of the Composition and Biophysical Properties of Two Plasma Membrane Preparations from CHO Cells

scientific article published on 10 April 2020

Pep7p provides a novel protein that functions in vesicle-mediated transport between the yeast Golgi and endosome

scientific article

Phosphatidylcholines from Pieris brassicae eggs activate an immune response in Arabidopsis

scientific article published on 28 September 2020

Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositol

scientific article

Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis.

scientific article

Prolonged starvation drives reversible sequestration of lipid biosynthetic enzymes and organelle reorganization in Saccharomyces cerevisiae

scientific article published on 11 March 2015

Proteasome-independent functions of ubiquitin in endocytosis and signaling

scientific article

Protection of C. elegans from anoxia by HYL-2 ceramide synthase

scientific article published in April 2009

Protein Sorting upon Exit from the Endoplasmic Reticulum

scientific article published on 01 January 2001

Protein and lipid requirements for endocytosis

scientific article

Protein traffic in the yeast endocytic and vacuolar protein sorting pathways

scientific article published on 01 August 1998

Quantitation of alpha-factor internalization and response during the Saccharomyces cerevisiae cell cycle

scientific article published on October 1991

Rapid protein extraction from Saccharomyces cerevisiae

scientific article published on 01 October 1994

Regulation of Glyoxysomal Enzymes during Germination of Cucumber: 2. Isolation and Immunological Detection of Isocitrate Lyase and Catalase

scientific article published in November 1978

Regulation of Glyoxysomal Enzymes during Germination of Cucumber: 3. IN VITRO TRANSLATION AND CHARACTERIZATION OF FOUR GLYOXYSOMAL ENZYMES.

scientific article published in January 1980

Regulation of Glyoxysomal Enzymes during Germination of Cucumber: I. Developmental Changes in Cotyledonary Protein, RNA, and Enzyme Activities during Germination

scientific article published in October 1978

Regulation of glyoxysomal enzymes during germination of cucumber. Temporal changes in translatable mRNAs for isocitrate lyase and malate synthase

scientific article published in December 1980

Rho1p mutations specific for regulation of β(1→3)glucan synthesis and the order of assembly of the yeast cell wall

scientific article published on 01 June 2002

Role of type I myosins in receptor-mediated endocytosis in yeast

scientific article

Rsp5 ubiquitin ligase is required for protein trafficking in Saccharomyces cerevisiae COPI mutants

scientific article

Rvs161p and Rvs167p, the two yeast amphiphysin homologs, function together in vivo

scientific article

Saccharomyces cerevisiae Arc35p works through two genetically separable calmodulin functions to regulate the actin and tubulin cytoskeletons

scientific article published on 01 February 2000

Saccharomyces cerevisiae GPI10, the functional homologue of human PIG-B, is required for glycosylphosphatidylinositol-anchor synthesis ⬇️

scientific article published on May 15, 1998

Scd5p and clathrin function are important for cortical actin organization, endocytosis, and localization of sla2p in yeast ⬇️

scientific article

Sch9 is a major target of TORC1 in Saccharomyces cerevisiae

scientific article

Skp1p and the F-box protein Rcy1p form a non-SCF complex involved in recycling of the SNARE Snc1p in yeast

scientific article

Sorting GPI-anchored proteins

scientific article published on February 2004

Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI

scientific article (publication date: 11 July 2011)

Specific requirements for the ER to Golgi transport of GPI-anchored proteins in yeast ⬇️

scientific article published on November 1, 1997

Specific retrieval of the exocytic SNARE Snc1p from early yeast endosomes

scientific article

Specific sterols required for the internalization step of endocytosis in yeast

scientific article published on November 1999

Sphingoid base is required for translation initiation during heat stress in Saccharomyces cerevisiae

scientific article

Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast

scientific article

Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae

scientific article

Sphingolipid Trafficking

Sphingolipid homeostasis in the web of metabolic routes

scientific article

Sphingolipid signaling in yeast: potential implications for understanding disease

scientific article published on January 2013

Sphingolipids and membrane targets for therapeutics

scientific article published on 18 March 2019

Sphingolipids are required for the stable membrane association of glycosylphosphatidylinositol-anchored proteins in yeast

scientific article published on 18 October 2002

Structure and conserved function of iso-branched sphingoid bases from the nematode

scientific article published on 06 March 2017

Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism

scientific article

Structure-function insights into direct lipid transfer between membranes by Mmm1-Mdm12 of ERMES.

scientific article published on 26 December 2017

Subunit IV of yeast cytochrome c oxidase: cloning and nucleotide sequencing of the gene and partial amino acid sequencing of the mature protein

scientific article

Survival strategies of a sterol auxotroph

scientific article

Synthetic multivalent antifungal peptides effective against fungi

scientific article published on 03 February 2014

Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis

scientific article

TEDS site phosphorylation of the yeast myosins I is required for ligand-induced but not for constitutive endocytosis of the G protein-coupled receptor Ste2p.

scientific article published on 13 February 2006

TORC1 inhibits GSK3-mediated Elo2 phosphorylation to regulate very long chain fatty acid synthesis and autophagy

scientific article

The Biochemistry Department of the University of Geneva: Understanding the Molecular Basis and Function of Intracellular Organization

scientific article published in December 2009

The ER v-SNAREs are required for GPI-anchored protein sorting from other secretory proteins upon exit from the ER.

scientific article

The Emp24 complex recruits a specific cargo molecule into endoplasmic reticulum-derived vesicles

scientific article

The F-box protein Rcy1p is involved in endocytic membrane traffic and recycling out of an early endosome in Saccharomyces cerevisiae

scientific article

The Golgi-localization of yeast Emp47p depends on its di-lysine motif but is not affected by the ret1-1 mutation in alpha-COP.

scientific article

The Ins and Outs of Protein Translocation

scientific article

The Rab GTPase Ypt1p and Tethering Factors Couple Protein Sorting at the ER to Vesicle Targeting to the Golgi Apparatus

scientific article published on 01 March 2002

The SAGA complex, together with transcription factors and the endocytic protein Rvs167p, coordinates the reprofiling of gene expression in response to changes in sterol composition in Saccharomyces cerevisiae.

scientific article published on 2 August 2017

The SwissLipids knowledgebase for lipid biology

scientific article published on 5 May 2015

The absence of Emp24p, a component of ER-derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi.

scientific article published on April 1995

The ins and outs of sphingolipid synthesis

scientific article

The long and short of fatty acid synthesis.

scientific article published in August 2007

The outer membrane of yeast mitochondria: isolation of outside-out sealed vesicles

scientific article

The peroxisomal enzyme L-PBE is required to prevent the dietary toxicity of medium-chain fatty acids

scientific article published on 26 September 2013

The presence of an ER exit signal determines the protein sorting upon ER exit in yeast

scientific article

The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus.

scientific article published on 18 February 2008

The yeast p24 complex regulates GPI-anchored protein transport and quality control by monitoring anchor remodeling

scientific article

The yeast p5 type ATPase, spf1, regulates manganese transport into the endoplasmic reticulum

scientific article

The yeast spt14 gene is homologous to the human PIG-A gene and is required for GPI anchor synthesis

scientific article published on April 1995

Three clathrin-dependent budding steps and cell polarity

scientific article published on 01 October 1993

Trafficking of glycosylphosphatidylinositol anchored proteins from the endoplasmic reticulum to the cell surface.

scientific article published on 8 October 2015

Transcription and translation initiation frequencies of the Escherichia coli lac operon

scientific article published on July 1977

Transcriptional studies on yeastSEC genes provide no evidence for regulation at the transcriptional level

article

Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle.

scientific article published on 16 April 2018

Transmembrane topology of ceramide synthase in yeast

scientific article published on September 2006

Transport through the yeast endocytic pathway occurs through morphologically distinct compartments and requires an active secretory pathway and Sec18p/N-ethylmaleimide-sensitive fusion protein

scientific article published in January 1997

Two Pathways of Sphingolipid Biosynthesis Are Separated in the Yeast Pichia pastoris ⬇️

scientific article published on February 8, 2011

Two yeast mutants defective in endocytosis are defective in pheromone response

scientific article published in August 1986

Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis

scientific article (publication date: 26 January 1996)

Understanding the diversity of membrane lipid composition.

scientific article published on 7 February 2018

Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells

scientific article

Vesicular and non-vesicular lipid export from the ER to the secretory pathway

scientific article published on 02 May 2019

Vesicular and nonvesicular transport of ceramide from ER to the Golgi apparatus in yeast

scientific article

Where sterols are required for endocytosis

scientific article

Why do cells require heat shock proteins to survive heat stress?

scientific article published on January 2004

Yeast ARV1 is required for efficient delivery of an early GPI intermediate to the first mannosyltransferase during GPI assembly and controls lipid flow from the endoplasmic reticulum

scientific article

Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins

scientific article

Yeast Ras regulates the complex that catalyzes the first step in GPI-anchor biosynthesis at the ER.

scientific article

Yeast actin cytoskeleton mutants accumulate a new class of Golgi-derived secretary vesicle

scientific article published on August 1997

Yeast as a model system for studying lipid homeostasis and function

scientific article published on 21 July 2012

Yeast ceramide synthases, Lag1 and Lac1, have distinct substrate specificity

scientific article published on 24 June 2019

Yeast endocytosis

scientific article published on August 1993

Yeast endocytosis assays

scientific article (publication date: 1991)

Yeast lipid analysis and quantification by mass spectrometry

scientific article published on March 2010

Yeast mitochondrial outer membrane specifically binds cytoplasmically-synthesized precursors of mitochondrial proteins.

scientific article

Yeast pheromone receptor endocytosis and hyperphosphorylation are independent of G protein-mediated signal transduction

scientific article published on 01 November 1992

end3 and end4: two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cerevisiae

scientific article

end5, end6, and end7: mutations that cause actin delocalization and block the internalization step of endocytosis in Saccharomyces cerevisiae

scientific article

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