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List of works by Hartmut Oschkinat

1 H NMR assignments of sidechain conformations in proteins using a high-dimensional potential in the simulated annealing calculations

scientific article published on 01 July 1990

1 H, 15 N and 13C assignments of the cysteine protease inhibitor Chagasin from Trypanosoma cruzi

13C-labeled tyrosine residues as local IR probes for monitoring conformational changes in peptides and proteins

scientific article published in July 2005

1H detection in MAS solid-state NMR spectroscopy of biomacromolecules employing pulsed field gradients for residual solvent suppression

scientific article

1H, 13C and 15N resonance assignment of the human Spred2 EVH1 domain

scientific article

2D(13)C-(13)C MAS NMR correlation spectroscopy with mixing by true (1)H spin diffusion reveals long-range intermolecular distance restraints in ultra high magnetic field

scientific article published in August 2002

A 3-D structural model of solid self-assembled chlorophyll a/H(2)O from multispin labeling and MAS NMR 2-D dipolar correlation spectroscopy in high magnetic field.

scientific article

A 6 bp Z-DNA hairpin binds two Zα domains from the human RNA editing enzyme ADAR1

article

A Floquet description of phase alternated sequences for efficient homonuclear recoupling in solid perdeuterated systems

scientific article published on 5 June 2013

A MAS NMR study of the bacterial ABC transporter ArtMP.

scientific article published in March 2010

A comparison of NCO and NCA transfer methods for biological solid-state NMR spectroscopy

scientific article published on 2 November 2011

A modified strategy for sequence specific assignment of protein NMR spectra based on amino acid type selective experiments

A modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions.

scientific article published on 6 April 2015

A novel subtype of AP-1-binding motif within the palmitoylated trans-Golgi network/endosomal accessory protein Gadkin/gamma-BAR

scientific article

A sequential assignment procedure for proteins that have intermediate line widths in MAS NMR spectra: amyloid fibrils of human CA150.WW2.

scientific article published in August 2008

A small region in phosducin inhibits G-protein betagamma-subunit function.

scientific article published on August 1997

A software framework for analysing solid-state MAS NMR data.

scientific article

A software tool for the prediction of Xaa-Pro peptide bond conformations in proteins based on 13C chemical shift statistics

scientific article

A well-defined Pd hybrid material for the Z-selective semihydrogenation of alkynes characterized at the molecular level by DNP SENS.

scientific article published on 19 August 2013

Addressing protein-protein interactions with small molecules: a Pro-Pro dipeptide mimic with a PPII helix conformation as a module for the synthesis of PRD-binding ligands

scientific article published on September 2010

AhR sensing of bacterial pigments regulates antibacterial defence.

scientific article published on 13 August 2014

Alterations in creatine metabolism observed in experimental autoimmune myocarditis using ex vivo proton magic angle spinning MRS.

scientific article published on 7 October 2015

Amino acid type-selective backbone 1H-15N-correlations for Arg and Lys.

scientific article published in August 2001

An approach to global fold determination using limited NMR data from larger proteins selectively protonated at specific residue types.

scientific article

An integrated approach to structural genomics.

scientific article

Antagonist design through forced electrostatic mismatch

scientific article published on 01 October 1994

Antigen 85C inhibition restricts Mycobacterium tuberculosis growth through disruption of cord factor biosynthesis

scientific article published on 30 January 2012

Application of amino acid type-specific 1H- and 14N-labeling in a 2H-, 15N-labeled background to a 47 kDa homodimer: potential for NMR structure determination of large proteins

scientific article published in May 1999

Aspects of receptor binding and signalling of interleukin-4 investigated by site-directed mutagenesis and NMR spectroscopy

scientific article

Assigning large proteins in the solid state: a MAS NMR resonance assignment strategy using selectively and extensively 13C-labelled proteins

scientific article

Assignment and Secondary-Structure Determination of Monomeric Bovine Seminal Ribonuclease Employing Computer-Assisted Evaluation of Homonuclear Three-Dimensional 1H-NMR Spectra

scientific article published on 01 April 1995

Assignment of amide proton signals by combined evaluation of HN, NN and HNCA MAS-NMR correlation spectra

scientific article

Assignment of protein nmr spectra in the light of homonuclear 3D spectroscopy: An automatable procedure based on 3D TOCSY-TOCSY and 3D TOCSY-NOESY

article by Hartmut Oschkinat et al published May 1991 in Biopolymers

Assignment of the nonexchanging protons of the alpha-spectrin SH3 domain by two- and three-dimensional 1H-13C solid-state magic-angle spinning NMR and comparison of solution and solid-state proton chemical shifts.

scientific article

Automated NOESY interpretation with ambiguous distance restraints: the refined NMR solution structure of the pleckstrin homology domain from beta-spectrin

scientific article

Automated assignment of multidimensional nuclear magnetic resonance spectra.

scientific article published on January 1994

Azides derived from colchicine and their use in library synthesis: A practical entry to new bioactive derivatives of an old natural drug.

scientific article

Backbone and sidechain 1H, 13C and 15N resonance assignments of the Bright/ARID domain from the human JARID1C (SMCX) protein

scientific article

Backbone and sidechain 1H, 13C and 15N resonance assignments of the RGS domain from human RGS14.

scientific article

Biosynthesis of riboflavin in archaea studies on the mechanism of 3,4-dihydroxy-2-butanone-4-phosphate synthase of Methanococcus jannaschii

scientific article published on 27 August 2002

Bridging the gap: A set of selective 1H-15N-correlations to link sequential neighbors of prolines

scientific article published on 01 August 2000

Broadband excitation pulses for high-field solid-state nuclear magnetic resonance spectroscopy

scientific article published on April 2012

Characterization of (1)H-(1)H distances in a uniformly (2)H,(15)N-labeled SH3 domain by MAS solid-state NMR spectroscopy (section sign).

scientific article

Characterization of membrane proteins in isolated native cellular membranes by dynamic nuclear polarization solid-state NMR spectroscopy without purification and reconstitution.

scientific article

Characterization of pheophytin ground states in Rhodobacter sphaeroides R26 photosynthetic reaction centers from multispin pheophytin enrichment and 2-D 13C MAS NMR dipolar correlation spectroscopy

scientific article published on 01 June 1997

Chemical shift assignments and secondary structure prediction for Q4DY78, a conserved kinetoplastid-specific protein from Trypanosoma cruzi

scientific article published on 29 June 2016

Collective exchange processes reveal an active site proton cage in bacteriorhodopsin

scientific article published on 03 January 2020

Combining SPOT synthesis and native peptide ligation to create large arrays of WW protein domains

scientific article

Comparative structural and energetic analysis of WW domain-peptide interactions

scientific article

Conformational Variability of Chicken Cystatin

article

Cryogenic temperature effects and resolution upon slow cooling of protein preparations in solid state NMR.

scientific article published on 9 August 2011

Delay of phagosome maturation by a mycobacterial lipid is reversed by nitric oxide

scientific article

Design of N-substituted peptomer ligands for EVH1 domains

scientific article

Detection of dynamic water molecules in a microcrystalline sample of the SH3 domain of alpha-spectrin by MAS solid-state NMR.

scientific article

Detection of metabolites in body fluids and biological tissue by a 1D soft COSY technique

scientific article

Determination of solid-state NMR structures of proteins by means of three-dimensional 15N-13C-13C dipolar correlation spectroscopy and chemical shift analysis

scientific article

Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR

scientific article (publication date: 24 January 2017)

Discovery of low-molecular-weight ligands for the AF6 PDZ domain

scientific article

Discovery, structure-activity relationship studies, and crystal structure of nonpeptide inhibitors bound to the Shank3 PDZ domain

scientific article

Double-nucleus enhanced recoupling for efficient 13C MAS NMR correlation spectroscopy of perdeuterated proteins

scientific article

Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinity

scientific article

Dynamic Nuclear Polarization Enhanced MAS NMR Spectroscopy for Structural Analysis of HIV-1 Protein Assemblies

scientific article published on 28 December 2015

Dynamic Nuclear Polarization Provides New Insights into Chromophore Structure in Phytochrome Photoreceptors

scientific article

Dynamic nuclear polarization enhanced NMR in the solid-state

scientific article published in January 2013

Dynamic nuclear polarization of deuterated proteins

scientific article published in October 2010

Dynamic nuclear polarization of spherical nanoparticles

scientific article published on 6 November 2013

EVH1 domains: structure, function and interactions

scientific article

Efficiency of Water-Soluble Nitroxide Biradicals for Dynamic Nuclear Polarization in Rotating Solids at 9.4 T: bcTol-M and cyolyl-TOTAPOL as New Polarizing Agents

Efficient modeling of symmetric protein aggregates from NMR data

scientific article

Evidence for tyrosine-linked glycosaminoglycan in a bacterial surface protein

scientific article

Fast passage dynamic nuclear polarization on rotating solids

scientific article published on 25 August 2012

General structural motifs of amyloid protofilaments

scholarly article

Heteronuclear relaxation study of the PH domain of beta-spectrin: restriction of loop motions upon binding inositol trisphosphate.

scientific article published in July 1998

High yield expression and purification of isotopically labelled human endothelin-1 for use in NMR studies

scientific article

High-throughput three-dimensional protein structure determination.

scientific article

Host monitoring of quorum sensing during Pseudomonas aeruginosa infection

scientific article published on 01 December 2019

Improved dynamic nuclear polarization surface-enhanced NMR spectroscopy through controlled incorporation of deuterated functional groups

scientific article published on 4 January 2013

Improving the refolding yield of interleukin-4 through the optimization of local interactions

scientific article published on 01 December 2000

In support of the BMRB.

scientific article published in September 2012

Influence of chemical shift tolerances on NMR structure calculations using ARIA protocols for assigning NOE data.

scientific article

Intermolecular protein-RNA interactions revealed by 2D 31P-15N magic angle spinning solid-state NMR spectroscopy

article

J-deconvolution using maximum entropy reconstruction applied to 13C-13C solid-state cross-polarization magic-angle-spinning NMR of proteins

scientific article

Large protein complexes with extreme rotational correlation times investigated in solution by magic-angle-spinning NMR spectroscopy

scientific article published in November 2009

Large-scale purification of ribosome-nascent chain complexes for biochemical and structural studies

scientific article

Letter to the Editor:1H,13C and15N resonance assignments of the C-terminal BRCT domain from human BRCA1

scientific article published on 01 October 2004

Light-Dark Adaptation of Channelrhodopsin Involves Photoconversion between the all-trans and 13-cis Retinal Isomers

scientific article

Lipophilic prodrugs of a triazole-containing colchicine analogue in liposomes: biological effects on human tumor cells

scientific article published on September 2013

Loop 3 of short neurotoxin II is an additional interaction site with membrane-bound nicotinic acetylcholine receptor as detected by solid-state NMR spectroscopy

scientific article

Low-power polarization transfer between deuterons and spin-1/2 nuclei using adiabatic RESPIRATIONCP in solid-state NMR

MUSIC and aromatic residues: amino acid type-selective (1)H-(15)N correlations, III.

scientific article

Measurement of multiple psi torsion angles in uniformly 13C,15N-labeled alpha-spectrin SH3 domain using 3D 15N-13C-13C-15N MAS dipolar-chemical shift correlation spectroscopy

scientific article

Multiplicity-Selective Coherence Transfer Steps for the Design of Amino Acid-Selective Experiments-A Triple-Resonance Experiment Selective for Asn and Gln

scientific article

N-terminal domain of  B-crystallin provides a conformational switch for multimerization and structural heterogeneity

scientific article

NMR Investigations of the Role of the Sugar Moiety in Glycosylated Recombinant Human Granulocyte-Colony-Stimulating Factor

scientific article published on 01 July 1997

NMR analysis of site-specific ligand binding in oligomeric proteins. Dynamic studies on the interaction of riboflavin synthase with trifluoromethyl-substituted intermediates.

scientific article

NMR assignment of human RGS18.

scientific article published on 9 September 2006

NMR structure of the Wnt modulator protein Sclerostin

scientific article

NMR studies on the 46-kDa dimeric protein, 3,4-dihydroxy-2-butanone 4-phosphate synthase, using 2H, 13C, and 15N-labelling

scientific article published on 01 April 1999

Neurotoxin II bound to acetylcholine receptors in native membranes studied by dynamic nuclear polarization NMR.

scientific article

On The Potential of Dynamic Nuclear Polarization Enhanced Diamonds in Solid-State and Dissolution (13) C NMR Spectroscopy

scientific article

Optimal (2)H rf Pulses and (2)H-(13)C Cross-Polarization Methods for Solid-State (2)H MAS NMR of Perdeuterated Proteins

scientific article published on 12 May 2011

Optimum levels of exchangeable protons in perdeuterated proteins for proton detection in MAS solid-state NMR spectroscopy

scientific article

Out-and-back 13C-13C scalar transfers in protein resonance assignment by proton-detected solid-state NMR under ultra-fast MAS.

scientific article published on 29 June 2013

Perspectives on NMR in drug discovery: a technique comes of age

scientific article

Pigmentierungschemie und radikalbasierter Kollagenabbau bei Alkaptonurie und Arthrose

scientific article published in 2020

Practical aspects of high-sensitivity multidimensional ¹³C MAS NMR spectroscopy of perdeuterated proteins

scientific article published in March 2012

Preferential and Specific Binding of Human αB-Crystallin to a Cataract-Related Variant of γS-Crystallin

scientific article

Proton-detected solid-state NMR spectroscopy of fibrillar and membrane proteins.

scientific article published on 14 April 2011

Purification and characterization of a chicken egg white cystatin variant expressed in an Escherichia coli pIN-III-ompA system

scientific article published in August 1991

Quadruple-resonance magic-angle spinning NMR spectroscopy of deuterated solid proteins

scientific article published on 29 January 2014

Quantification of PDZ domain specificity, prediction of ligand affinity and rational design of super-binding peptides

scientific article

Quantitative and Qualitative Analysis of Surface Modified Cellulose Utilizing TGA-MS

scientific article published on 25 May 2016

Quantitative study of the effects of chemical shift tolerances and rates of SA cooling on structure calculation from automatically assigned NOE data

scientific article

Rab7: NMR and kinetics analysis of intact and C-terminal truncated constructs

article

Radio frequency assisted homonuclear recoupling - a Floquet description of homonuclear recoupling via surrounding heteronuclei in fully protonated to fully deuterated systems

scientific article published on 18 January 2011

Rapid proton-detected NMR assignment for proteins with fast magic angle spinning

scientific article

Rapid solid-state NMR of deuterated proteins by interleaved cross-polarization from ¹H and ²H nuclei

scientific article published on 9 November 2011

Receptor binding properties of four-helix-bundle growth factors deduced from electrostatic analysis.

scientific article published on June 1994

Recognition of proline-rich motifs by protein-protein-interaction domains

scientific article published in May 2005

Reduced activity of alkaline phosphatase due to host-guest interactions with humic superstructures

scientific article published on 13 August 2013

Regulation of endosomal membrane traffic by a Gadkin/AP-1/kinesin KIF5 complex

scientific article

Relaxation, equilibrium oligomerization, and molecular symmetry of the VASP (336-380) EVH2 tetramer

scientific article published in September 2002

Resonance assignment of the RGS domain of human RGS10

scientific article published on 19 December 2006

SNARE motif-mediated sorting of synaptobrevin by the endocytic adaptors clathrin assembly lymphoid myeloid leukemia (CALM) and AP180 at synapses

scientific article

SOLARIA: A Protocol for Automated Cross-Peak Assignment and Structure Calculation for Solid-State Magic-Angle Spinning NMR Spectroscopy

scholarly article by Michele Fossi et al published 26 September 2005 in Angewandte Chemie International Edition

Secondary chemical shifts in immobilized peptides and proteins: a qualitative basis for structure refinement under magic angle spinning

scientific article published on 01 August 2001

Sensitivity and resolution of proton detected spectra of a deuterated protein at 40 and 60 kHz magic-angle-spinning

scientific article published on 8 February 2015

Signal selection in high-resolution NMR by pulsed field gradients

scientific article published in March 1999

Small-Molecule Scaffolds for CYP51 Inhibitors Identified by High-Throughput Screening and Defined by X-Ray Crystallography

scientific article

Small-molecule inhibitors of AF6 PDZ-mediated protein-protein interactions.

scientific article

Solid-State NMR of Matrix Metalloproteinase 12: An Approach Complementary to Solution NMR

scholarly article by Stéphane Balayssac published in March 2007

Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin oligomers

scientific article

Solid-state magic-angle spinning NMR of membrane proteins and protein-ligand interactions

scientific article published on 22 October 2011

Solid-state magic-angle spinning NMR of outer-membrane protein G from Escherichia coli

scientific article

Solution conformation of thymosin beta 4: a nuclear magnetic resonance and simulated annealing study

scientific article

Solution structure and backbone dynamics of the Trypanosoma cruzi cysteine protease inhibitor chagasin

scientific article

Solution structure of the receptor tyrosine kinase EphB2 SAM domain and identification of two distinct homotypic interaction sites

scientific article

Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1.

scientific article published in December 2004

Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope

scientific article

Specific interactions between the syntrophin PDZ domain and voltage-gated sodium channels

scientific article

Spectral editing: selection of methyl groups in multidimensional solid-state magic-angle spinning NMR.

scientific article published on 22 September 2006

Structural analysis of WW domains and design of a WW prototype

scientific article

Structural analysis of a signal peptide inside the ribosome tunnel by DNP MAS NMR

scientific article

Structural basis for APPTPPPLPP peptide recognition by the FBP11WW1 domain

scientific article published in April 2005

Structural basis for the dissociation of α-synuclein fibrils triggered by pressure perturbation of the hydrophobic core

scientific article

Structural biology applications of solid state MAS DNP NMR.

scientific article published on 11 April 2016

Structural characterization of a new binding motif and a novel binding mode in group 2 WW domains

scientific article

Structure of a protein determined by solid-state magic-angle-spinning NMR spectroscopy

scientific article

Structure of outer membrane protein G in lipid bilayers

scientific article published on 12 December 2017

Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide.

scientific article

Structure of the binding site for inositol phosphates in a PH domain

scientific article

Structure of the pleckstrin homology domain from beta-spectrin.

scientific article

Studies of the intermediary metabolism in cultured cells of the insect Spodoptera frugiperda using 13C- or 15N-labelled tracers

scientific article

Studying the Conformation of a Silaffin-Derived Pentalysine Peptide Embedded in Bioinspired Silica using Solution and Dynamic Nuclear Polarization Magic-Angle Spinning NMR.

scientific article published on 9 October 2015

Sulindac-derived Ras pathway inhibitors target the Ras-Raf interaction and downstream effectors in the Ras pathway

scientific article published on January 2004

Surface Binding of TOTAPOL Assists Structural Investigations of Amyloid Fibrils by Dynamic Nuclear Polarization NMR Spectroscopy

scientific article published on 4 May 2016

Synthesis of an Array Comprising 837 Variants of the hYAP WW Protein Domain This work was supported by the DFG (INK 16/B1-1), by the Fonds der Chemischen Industrie, and by the Universitätsklinikum Charité Berlin

scientific article published in March 2001

Temperature dependence of cross-effect dynamic nuclear polarization in rotating solids: advantages of elevated temperatures

scientific article published on 28 October 2016

The NMR structure of the 47-kDa dimeric enzyme 3,4-dihydroxy-2-butanone-4-phosphate synthase and ligand binding studies reveal the location of the active site

scientific article

The SEP domain of p47 acts as a reversible competitive inhibitor of cathepsin L.

scientific article

The ScPex13p SH3 domain exposes two distinct binding sites for Pex5p and Pex14p

scientific article (publication date: 7 March 2003)

The clip-segment of the von Willebrand domain 1 of the BMP modulator protein Crossveinless 2 is preformed

scientific article

The effect of biradical concentration on the performance of DNP-MAS-NMR.

scientific article published on 8 January 2012

The interaction of thrombin with fibrinogen. A structural basis for its specificity

scientific article

The mechanism of denaturation and the unfolded state of the α-helical membrane-associated protein Mistic.

scientific article

The oxidized subunit B8 from human complex I adopts a thioredoxin fold

scientific article

The solution structure of an N-terminally truncated version of the yeast CDC24p PB1 domain shows a different beta-sheet topology

scientific article published in July 2005

The solution structure of the N-terminal domain of E3L shows a tyrosine conformation that may explain its reduced affinity to Z-DNA in vitro

scientific article

The solution structure of the SODD BAG domain reveals additional electrostatic interactions in the HSP70 complexes of SODD subfamily BAG domains

scientific article

The solution structure of the Zalpha domain of the human RNA editing enzyme ADAR1 reveals a prepositioned binding surface for Z-DNA

scientific article

The solution structure of the core of mesoderm development (MESD), a chaperone for members of the LDLR-family

scientific article

The structure of MESD45-184 brings light into the mechanism of LDLR family folding

scientific article

The structures of native phosphorylated chicken cystatin and of a recombinant unphosphorylated variant in solution

scientific article

The structures of the active center in dark-adapted bacteriorhodopsin by solution-state NMR spectroscopy

scientific article

Theoretical aspects of Magic Angle Spinning - Dynamic Nuclear Polarization.

scientific article published on 13 July 2015

Three-dimensional NMR spectroscopy of a protein in solution ⬇️

scientific article published on March 24, 1988

Three-dimensional deuterium-carbon correlation experiments for high-resolution solid-state MAS NMR spectroscopy of large proteins

scientific article

Tools for the automated assignment of high-resolution three-dimensional protein NMR spectra based on pattern recognition techniques

scientific article published in October 1997

Towards structure determination of neurotoxin II bound to nicotinic acetylcholine receptor: a solid-state NMR approach.

scientific article published in April 2004

Triple Resonance Cross-Polarization for More Sensitive 13C MAS NMR Spectroscopy of Deuterated Proteins

Two-dimensional nuclear magnetic resonance studies of an intercalation complex between the novel semisynthetic anthracycline 3′-deamino-3′-(2-methoxy-4-morpholinyl)-doxorubicin and the hexanucleotide duplex d(CGTACG)

scientific article published on 01 December 1992

Ultrafast folding of WW domains without structured aromatic clusters in the denatured state

scientific article

Using flexible loop mimetics to extend  -value analysis to secondary structure interactions

scientific article

WW domain sequence activity relationships identified using ligand recognition propensities of 42 WW domains

scientific article

[2,3-(13)C]-labeling of aromatic residues--getting a head start in the magic-angle-spinning NMR assignment of membrane proteins

scientific article

alphaB-crystallin: a hybrid solid-state/solution-state NMR investigation reveals structural aspects of the heterogeneous oligomer

scientific article

bcTol : a highly water-soluble biradical for efficient dynamic nuclear polarization of biomolecules

scientific article published on 10 May 2016

pH-Dependent Protonation of Surface Carboxylate Groups in PsbO Enables Local Buffering and Triggers Structural Changes

scientific article published on 12 January 2020

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