List of works - Eckhard Jankowsky

A helicase links upstream ORFs and RNA structure

scientific article published on 27 November 2018

AMP sensing by DEAD-box RNA helicases

scientific article published on 20 May 2013

ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwinding

scientific article

ATP- and ADP-dependent modulation of RNA unwinding and strand annealing activities by the DEAD-box protein DED1.

scientific article

Active disruption of an RNA-protein interaction by a DExH/D RNA helicase

scientific article

An Arabidopsis ATP-dependent, DEAD-box RNA helicase loses activity upon IsoAsp formation but is restored by PROTEIN ISOASPARTYL METHYLTRANSFERASE.

scientific article published on 31 July 2013

Analysis of duplex unwinding by RNA helicases using stopped-flow fluorescence spectroscopy.

scientific article

Angiogenin-cleaved tRNA halves interact with cytochrome c, protecting cells from apoptosis during osmotic stress

scientific article

Approaches for measuring the dynamics of RNA-protein interactions

scientific article published on 20 August 2019

Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3.

scientific article published on 23 November 2015

Backbone tracking by the SF2 helicase NPH-II.

scientific article

Biochemistry: indifferent chaperones

scientific article published in October 2007

Biophysics: helicase snaps back.

scientific article

Coupling between the DEAD-box RNA helicases Ded1p and eIF4A

scientific article

DEAD-box helicases as integrators of RNA, nucleotide and protein binding

scientific article

DEAD-box helicases form nucleotide-dependent, long-lived complexes with RNA.

scientific article

DEAD-box proteins unwind duplexes by local strand separation

scientific article

DEAD-box-protein-assisted RNA structure conversion towards and against thermodynamic equilibrium values

scientific article published on 2 March 2007

Degradation of hypomodified tRNA(iMet) in vivo involves RNA-dependent ATPase activity of the DExH helicase Mtr4p

scientific article

Discovery of antivirulence agents against methicillin-resistant Staphylococcus aureus

scientific article published on 20 May 2013

Discriminatory RNP remodeling by the DEAD-box protein DED1.

scientific article

Division of Labor in an Oligomer of the DEAD-Box RNA Helicase Ded1p

scientific article published on 22 July 2015

Do DEAD-box proteins promote group II intron splicing without unwinding RNA?

scientific article published on October 2007

Duplex unwinding and RNP remodeling with RNA helicases

scientific article

Duplex unwinding with DEAD-box proteins.

scientific article published in January 2010

Dynamic regulation of alternative splicing by silencers that modulate 5' splice site competition

scientific article published on December 2008

Efficient Improvement of Hammerhead Ribozyme Mediated Cleavage of Long Substrates by Oligonucleotide Facilitators†

scientific article published in 1996

From exotic to exciting

scientific article published in April 2015

From unwinding to clamping - the DEAD box RNA helicase family

scientific article published on 22 July 2011

Function of the C-terminal domain of the DEAD-box protein Mss116p analyzed in vivo and in vitro

scientific article published on 22 November 2007

Helicase Multitasking in Ribosome Assembly

article published in 2009

Hidden specificity in an apparently nonspecific RNA-binding protein

scientific article published on 22 September 2013

Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms

scientific journal article

Intrinsic RNA binding by the eukaryotic initiation factor 4F depends on a minimal RNA length but not on the m7G cap.

scientific article published on 04 May 2009

Involvement of DEAD-box proteins in group I and group II intron splicing. Biochemical characterization of Mss116p, ATP hydrolysis-dependent and -independent mechanisms, and general RNA chaperone activity

scientific article

Methods in enzymology. Preface.

scientific article

Mutational analysis of the yeast RNA helicase Sub2p reveals conserved domains required for growth, mRNA export, and genomic stability

scientific article published on 20 August 2013

Oligonucleotide facilitators enable a hammerhead ribozyme to cleave long RNA substrates with multiple-turnover activity

scientific article published in May 1998

Oligonucleotide facilitators may inhibit or activate a hammerhead ribozyme

scientific article

Prediction of functional tertiary interactions and intermolecular interfaces from primary sequence data

scientific article published in January 2005

Protein displacement by DExH/D "RNA helicases" without duplex unwinding

scientific article published in April 2004

RNA helicases at work: binding and rearranging ⬇️

scientific article published on January 1, 2011

RNA helicases--one fold for many functions

scientific article published on 15 June 2007

RNA helicases: versatile ATP-driven nanomotors

scientific article published in December 2005

RNA unwinding activity of the hepatitis C virus NS3 helicase is modulated by the NS5B polymerase

scientific article published on 8 January 2008

RNA unwinding by the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex

scientific article

Remodeling of ribonucleoprotein complexes with DExH/D RNA helicases

scientific article published on 25 August 2006

Robust translocation along a molecular monorail: the NS3 helicase from hepatitis C virus traverses unusually large disruptions in its track

scientific article published on 20 March 2006

SF1 and SF2 helicases: family matters

scientific article

Specificity and nonspecificity in RNA-protein interactions

scientific article (publication date: September 2015)

Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation

scientific article

Substrate selectivity by the exonuclease Rrp6p

scientific article published on 26 December 2019

The DEAD-box protein Ded1 modulates translation by the formation and resolution of an eIF4F-mRNA complex

scientific article

The DEAD-box protein Ded1 unwinds RNA duplexes by a mode distinct from translocating helicases

The DEAH-box protein PRP22 is an ATPase that mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes

scientific article

The DExH protein NPH-II is a processive and directional motor for unwinding RNA

scientific article published in Nature

The DExH/D protein family database

scientific article published on January 2000

The Ded1/DDX3 subfamily of DEAD-box RNA helicases

scientific article published on July 2014

The RNA helicase Mtr4p modulates polyadenylation in the TRAMP complex

scientific article

The RNA helicase database ⬇️

scientific article published on November 25, 2010

The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding

scientific article

The kinetic landscape of an RNA-binding protein in cells

scientific article published on 10 February 2021

Unwinding by local strand separation is critical for the function of DEAD-box proteins as RNA chaperones

scientific article published on 23 April 2009

Unwinding initiation by the viral RNA helicase NPH-II.

scientific article published on 6 December 2011

[10] Using DNAzylnes to cut, process, and map RNA molecules for structural studies or modification

scientific article published on 01 January 2000

mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties

scientific article

List of works by Eckhard Jankowsky

A helicase links upstream ORFs and RNA structure

AMP sensing by DEAD-box RNA helicases

ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwinding

ATP- and ADP-dependent modulation of RNA unwinding and strand annealing activities by the DEAD-box protein DED1.

Active disruption of an RNA-protein interaction by a DExH/D RNA helicase

An Arabidopsis ATP-dependent, DEAD-box RNA helicase loses activity upon IsoAsp formation but is restored by PROTEIN ISOASPARTYL METHYLTRANSFERASE.

Analysis of duplex unwinding by RNA helicases using stopped-flow fluorescence spectroscopy.

Angiogenin-cleaved tRNA halves interact with cytochrome c, protecting cells from apoptosis during osmotic stress

Approaches for measuring the dynamics of RNA-protein interactions

Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3.

Backbone tracking by the SF2 helicase NPH-II.

Biochemistry: indifferent chaperones

Biophysics: helicase snaps back.

Coupling between the DEAD-box RNA helicases Ded1p and eIF4A

DEAD-box helicases as integrators of RNA, nucleotide and protein binding

DEAD-box helicases form nucleotide-dependent, long-lived complexes with RNA.

DEAD-box proteins unwind duplexes by local strand separation

DEAD-box-protein-assisted RNA structure conversion towards and against thermodynamic equilibrium values

Degradation of hypomodified tRNA(iMet) in vivo involves RNA-dependent ATPase activity of the DExH helicase Mtr4p

Discovery of antivirulence agents against methicillin-resistant Staphylococcus aureus

Discriminatory RNP remodeling by the DEAD-box protein DED1.

Division of Labor in an Oligomer of the DEAD-Box RNA Helicase Ded1p

Do DEAD-box proteins promote group II intron splicing without unwinding RNA?

Duplex unwinding and RNP remodeling with RNA helicases

Duplex unwinding with DEAD-box proteins.

Dynamic regulation of alternative splicing by silencers that modulate 5' splice site competition

Efficient Improvement of Hammerhead Ribozyme Mediated Cleavage of Long Substrates by Oligonucleotide Facilitators†

From exotic to exciting

From unwinding to clamping - the DEAD box RNA helicase family

Function of the C-terminal domain of the DEAD-box protein Mss116p analyzed in vivo and in vitro

Helicase Multitasking in Ribosome Assembly

Hidden specificity in an apparently nonspecific RNA-binding protein

Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms

Intrinsic RNA binding by the eukaryotic initiation factor 4F depends on a minimal RNA length but not on the m7G cap.

Involvement of DEAD-box proteins in group I and group II intron splicing. Biochemical characterization of Mss116p, ATP hydrolysis-dependent and -independent mechanisms, and general RNA chaperone activity

Methods in enzymology. Preface.

Mutational analysis of the yeast RNA helicase Sub2p reveals conserved domains required for growth, mRNA export, and genomic stability

Oligonucleotide facilitators enable a hammerhead ribozyme to cleave long RNA substrates with multiple-turnover activity

Oligonucleotide facilitators may inhibit or activate a hammerhead ribozyme

Prediction of functional tertiary interactions and intermolecular interfaces from primary sequence data

Protein displacement by DExH/D "RNA helicases" without duplex unwinding

RNA helicases at work: binding and rearranging ⬇️

RNA helicases--one fold for many functions

RNA helicases: versatile ATP-driven nanomotors

RNA unwinding activity of the hepatitis C virus NS3 helicase is modulated by the NS5B polymerase

RNA unwinding by the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex

Remodeling of ribonucleoprotein complexes with DExH/D RNA helicases

Robust translocation along a molecular monorail: the NS3 helicase from hepatitis C virus traverses unusually large disruptions in its track

SF1 and SF2 helicases: family matters

Specificity and nonspecificity in RNA-protein interactions

Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation

Substrate selectivity by the exonuclease Rrp6p

The DEAD-box protein Ded1 modulates translation by the formation and resolution of an eIF4F-mRNA complex

The DEAD-box protein Ded1 unwinds RNA duplexes by a mode distinct from translocating helicases

The DEAH-box protein PRP22 is an ATPase that mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes

The DExH protein NPH-II is a processive and directional motor for unwinding RNA

The DExH/D protein family database

The Ded1/DDX3 subfamily of DEAD-box RNA helicases

The RNA helicase Mtr4p modulates polyadenylation in the TRAMP complex

The RNA helicase database ⬇️

The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding

The kinetic landscape of an RNA-binding protein in cells

Unwinding by local strand separation is critical for the function of DEAD-box proteins as RNA chaperones

Unwinding initiation by the viral RNA helicase NPH-II.

[10] Using DNAzylnes to cut, process, and map RNA molecules for structural studies or modification

mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties