Search filters

List of works by André Mitschler

Crystal packing modifies ligand binding affinity: The case of aldose reductase

scientific article

Crystal structure of a subcomplex of human transcription factor TFIID formed by TATA binding protein-associated factors hTAF4 (hTAF(II)135) and hTAF12 (hTAF(II)20)

scientific article

Frataxin from Psychromonas ingrahamii as a model to study stability modulation within the CyaY protein family

scientific article

IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors

scientific article

Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design

scientific article

Linear and extended: a common polyglutamine conformation recognized by the three antibodies MW1, 1C2 and 3B5H10

scientific article

Molecular recognition of agonist ligands by RXRs

scientific article

Probing the roles of two tryptophans surrounding the unique zinc coordination site in lipase family I.5

scientific article

Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10

scientific article

Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor

scientific article

Structural analysis of sulindac as an inhibitor of aldose reductase and AKR1B10

scientific article

Structural and functional studies of ReP1-NCXSQ, a protein regulating the squid nerve Na+/Ca2+ exchanger

scientific article

Structural characterization of metal binding to a cold-adapted frataxin

scientific article

The Effect of Halogen-to-Hydrogen Bond Substitution on Human Aldose Reductase Inhibition

scientific article

The role of the C-terminal region on the oligomeric state and enzymatic activity of Trypanosoma cruzi hypoxanthine phosphoribosyl transferase

scientific article

X-ray structure of the V301L aldo-keto reductase 1B10 complexed with NADP(+) and the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity

scientific article

X-ray-radiation-induced cooperative atomic movements in protein

scientific article