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List of works by Olaf-Georg Issinger

Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit

scientific article

Evolved to be active: sulfate ions define substrate recognition sites of CK2alpha and emphasise its exceptional role within the CMGC family of eukaryotic protein kinases

scientific article

First inactive conformation of CK2 alpha, the catalytic subunit of protein kinase CK2

scientific article

First structure of protein kinase CK2 catalytic subunit with an effective CK2β-competitive ligand

scientific article

Low-density crystal packing of human protein kinase CK2 catalytic subunit in complex with resorufin or other ligands: a tool to study the unique hinge-region plasticity of the enzyme without packing bias

scientific article

Modulation of human checkpoint kinase Chk1 by the regulatory beta-subunit of protein kinase CK2

scientific article (publication date: 7 August 2003)

Protein kinase CK2 inhibition is associated with the destabilization of HIF-1α in human cancer cells

scientific article

Protein kinase CK2 phosphorylates the Fas-associated factor FAF1 in vivo and influences its transport into the nucleus

scientific article (publication date: 10 July 2003)

The CK2 alpha/CK2 beta interface of human protein kinase CK2 harbors a binding pocket for small molecules

scientific article

The catalytic subunit of human protein kinase CK2 structurally deviates from its maize homologue in complex with the nucleotide competitive inhibitor emodin

scientific article

The interaction of CK2α and CK2β, the subunits of protein kinase CK2, requires CK2β in a preformed conformation and is enthalpically driven

scientific article

The pro-apoptotic FAS-associated factor 1 is specifically reduced in human gastric carcinomas

scientific article (publication date: October 2003)

The protein kinase CK2(Andante) holoenzyme structure supports proposed models of autoregulation and trans-autophosphorylation

scientific article

The subcellular distribution of the human ribosomal "stalk" components: P1, P2 and P0 proteins

scientific article (publication date: February 2003)