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List of works by Direk Limmathurotsakul

"Cost-effectiveness of interventions to improve hand hygiene in healthcare workers in middle-income hospital settings: a model-based analysis".

scientific article

'Antibiotic footprint' as a communication tool to aid reduction of antibiotic consumption

scientific article published on 01 August 2019

'Antibiotic footprint' as a communication tool to aid reduction of antibiotic consumption-authors' response

scientific article published on 01 November 2019

'Antibiotic footprint' as a communication tool to aid reduction of antibiotic consumption-authors' response

scientific article published on 01 March 2020

'Antibiotic footprint' as a communication tool to aid reduction of antibiotic consumption-authors' response

scientific article published on 01 September 2019

A current perspective on antimicrobial resistance in Southeast Asia

scientific article published in November 2017

A nonsense mutation in TLR5 is associated with survival and reduced IL-10 and TNF-α levels in human melioidosis

scientific article

A randomized controlled trial of granulocyte colony-stimulating factor for the treatment of severe sepsis due to melioidosis in Thailand

scientific article

A retrospective analysis of melioidosis in Cambodian children, 2009-2013

scientific article

A simple scoring system to differentiate between relapse and re-infection in patients with recurrent melioidosis

scientific article

Accuracy of a commercial IgM ELISA for the diagnosis of human leptospirosis in Thailand

scientific article published on March 2012

Accuracy of enzyme-linked immunosorbent assay using crude and purified antigens for serodiagnosis of melioidosis

scientific article

Accuracy of loop-mediated isothermal amplification for diagnosis of human leptospirosis in Thailand

scientific article

Activities of daily living associated with acquisition of melioidosis in northeast Thailand: a matched case-control study

scientific article

Antibiotic knowledge, attitudes and practices: new insights from cross-sectional rural health behaviour surveys in low-income and middle-income South-East Asia

scientific article published on 20 August 2019

Antibiotic use in poultry: a survey of eight farms in Thailand

scientific article published on 27 November 2017

Antibiotics and activity spaces: protocol of an exploratory study of behaviour, marginalisation and knowledge diffusion

scientific article published on 28 March 2018

Antibodies from patients with melioidosis recognize Burkholderia mallei but not Burkholderia thailandensis antigens in the indirect hemagglutination assay

scientific article

Antimicrobial Disk Susceptibility Testing of Leptospira spp. Using Leptospira Vanaporn Wuthiekanun (LVW) Agar

scientific article published on 8 June 2015

Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei

scientific article

Association of the Quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA) Score With Excess Hospital Mortality in Adults With Suspected Infection in Low- and Middle-Income Countries

scientific article published in The Journal of the American Medical Association

Automating the Generation of Antimicrobial Resistance Surveillance Reports: Proof-of-Concept Study Involving Seven Hospitals in Seven Countries

scientific article published on 02 October 2020

Barriers and Recommended Interventions to Prevent Melioidosis in Northeast Thailand: A Focus Group Study Using the Behaviour Change Wheel

scientific article

Biological relevance of colony morphology and phenotypic switching by Burkholderia pseudomallei

scientific article

Burkholderia Pseudomallei is genetically diverse in agricultural land in Northeast Thailand

scientific article

Burkholderia pseudomallei genome plasticity associated with genomic island variation

scientific article

Burkholderia pseudomallei in water supplies, southern Thailand

scientific article published on November 2014

Burkholderia pseudomallei is spatially distributed in soil in northeast Thailand

scientific article

Burkholderia pseudomallei: Challenges for the Clinical Microbiology Laboratory-a Response from the Front Line

scientific article published on March 2017

Capacity and Utilization of Blood Culture in Two Referral Hospitals in Indonesia and Thailand

scientific article published on 10 July 2017

Clinical Epidemiology of 7126 Melioidosis Patients in Thailand and the Implications for a National Notifiable Diseases Surveillance System

scientific article published on 19 November 2019

Clinical Epidemiology of Septic Arthritis Caused by Burkholderia pseudomallei and Other Bacterial Pathogens in Northeast Thailand

scientific article published on 2 October 2017

Clinical and molecular epidemiology of Staphylococcus argenteus infections in Thailand

scientific article

Clinical definitions of melioidosis

scientific article

Clinical epidemiology and outcomes of community acquired infection and sepsis among hospitalized patients in a resource limited setting in Northeast Thailand: A prospective observational study (Ubon-sepsis)

scientific article published in PLoS ONE

Clinical, environmental, and serologic surveillance studies of melioidosis in Gabon, 2012-2013

scientific article

Common TLR1 genetic variation is not associated with death from melioidosis, a common cause of sepsis in rural Thailand

scientific article

Comparative efficacy of interventions to promote hand hygiene in hospital: systematic review and network meta-analysis

scientific article (publication date: 2015)

Comparison of 2 chromogenic media for the detection of extended-spectrum β-lactamase producing Enterobacteriaceae stool carriage in nursing home residents

scientific article published on 11 November 2015

Comparison of two chromogenic media for the detection of vancomycin-resistant enterococcal carriage by nursing home residents

scientific article published on 04 May 2016

Comprehensive analysis of clinical Burkholderia pseudomallei isolates demonstrates conservation of unique lipid A structure and TLR4-dependent innate immune activation

scientific article published on 23 February 2018

Consensus guidelines for dosing of amoxicillin-clavulanate in melioidosis

scientific article

Correction: Epidemiology, Microbiology and Mortality Associated with Community-Acquired Bacteremia in Northeast Thailand: A Multicenter Surveillance Study.

scientific article published on 16 October 2013

Cost-effectiveness analysis of parenteral antimicrobials for acute melioidosis in Thailand

scientific article

Cost-effectiveness analysis of parenteral antimicrobials for acute melioidosis in Thailand

scholarly article by Viriya Hantrakun et al published December 2015 in Transactions of the Royal Society of Tropical Medicine and Hygiene

Defining the true sensitivity of culture for the diagnosis of melioidosis using Bayesian latent class models

scientific article

Detection and Characterization of Human Pegivirus 2, Vietnam

scholarly article by Nguyen To Anh et al published November 2018 in Emerging Infectious Diseases

Determinants of mortality in a combined cohort of 501 patients with HIV-associated Cryptococcal meningitis: implications for improving outcomes

scientific article published on 06 December 2013

Development and validation of Burkholderia pseudomallei-specific real-time PCR assays for clinical, environmental or forensic detection applications

scientific article

Development of Rapid Enzyme-Linked Immunosorbent Assays for Detection of Antibodies to Burkholderia pseudomallei

scientific article published on 24 February 2016

Development of a prototype lateral flow immunoassay (LFI) for the rapid diagnosis of melioidosis

scientific article

Development of ceftazidime resistance in an acute Burkholderia pseudomallei infection

scientific article published on 22 August 2012

Diagnostic accuracy of real-time PCR assays targeting 16S rRNA and lipL32 genes for human leptospirosis in Thailand: a case-control study

scientific article

Duration of exposure to multiple antibiotics is associated with increased risk of VRE bacteraemia: a nested case-control study

scientific article published on 13 March 2018

Early management of sepsis in medical patients in rural Thailand: a single-center prospective observational study

scientific article published on 02 December 2019

Effect of colony morphology variation of Burkholderia pseudomallei on intracellular survival and resistance to antimicrobial environments in human macrophages in vitro

scientific article

Effectiveness of a simplified method for isolation of Burkholderia pseudomallei from soil

scientific article published on 18 November 2011

Emergence of Melioidosis in Indonesia

scientific article published on 12 October 2015

Enzyme-linked immunosorbent assay for the diagnosis of melioidosis: better than we thought

scientific article

Epidemiology and burden of multidrug-resistant bacterial infection in a developing country

scientific article published on 06 September 2016

Epidemiology, microbiology and mortality associated with community-acquired bacteremia in northeast Thailand: a multicenter surveillance study

scientific article

Estimating the true accuracy of diagnostic tests for dengue infection using bayesian latent class models

scientific article published on 18 January 2013

Evaluating Burkholderia pseudomallei Bip proteins as vaccines and Bip antibodies as detection agents

scientific article published on 11 November 2007

Evaluation of Polysaccharide-Based Latex Agglutination Assays for the Rapid Detection of Antibodies to Burkholderia pseudomallei

scientific article

Evaluation of a latex agglutination assay for the identification of Burkholderia pseudomallei and Burkholderia mallei

scientific article

Evaluation of consensus method for the culture of Burkholderia pseudomallei in soil samples from Laos

article

Evolution of the Staphylococcus argenteus ST2250 Clone in Northeastern Thailand Is Linked with the Acquisition of Livestock-Associated Staphylococcal Genes

scientific article

Exonic sequencing identifies TLR1 genetic variation associated with mortality in Thais with melioidosis

scientific article published on 01 January 2019

Extended loop region of Hcp1 is critical for the assembly and function of type VI secretion system in Burkholderia pseudomallei

scientific article

Faculty of 1000 evaluation for Randomised clinical trial investigating the specificity of a novel skin test (C-Tb) for diagnosis of M. tuberculosis infection

scholarly article published 3 July 2013

Fatal melioidosis in goats in Bangkok, Thailand

scientific article

Feasibility and initial outcomes of a multifaceted prevention programme of melioidosis in diabetic patients in Ubon Ratchathani, northeast Thailand

scholarly article by Pornpan Suntornsut et al published September 2018 in PLoS Neglected Tropical Diseases

Feasibility of modified surviving sepsis campaign guidelines in a resource-restricted setting based on a cohort study of severe S. aureus sepsis [corrected]

scientific article

Fool's gold: Why imperfect reference tests are undermining the evaluation of novel diagnostics: a reevaluation of 5 diagnostic tests for leptospirosis

scientific article

Gamma Interferon Supplementation for Melioidosis ⬇️

scientific article published on October 1, 2010

Gastrointestinal tract involvement in melioidosis

scientific article published on April 2017

Genetic diversity and microevolution of Burkholderia pseudomallei in the environment

scientific article

Genome sequencing defines phylogeny and spread of methicillin-resistant Staphylococcus aureus in a high transmission setting

scientific article published on 9 December 2014

Global Burden and Challenges of Melioidosis

scientific article published on 29 January 2018

Global and regional dissemination and evolution of Burkholderia pseudomallei

scientific article published on 23 January 2017

Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis

scientific article

Harnessing alternative sources of antimicrobial resistance data to support surveillance in low-resource settings

scholarly article by Elizabeth A Ashley et al published 1 March 2019 in Journal of Antimicrobial Chemotherapy

High-throughput mRNA profiling characterizes the expression of inflammatory molecules in sepsis caused by Burkholderia pseudomallei

scientific article published on 19 March 2007

Highly sensitive direct detection and quantification of Burkholderia pseudomallei bacteria in environmental soil samples by using real-time PCR.

scientific article

Host responses to melioidosis and tuberculosis are both dominated by interferon-mediated signaling

scientific article

How to Determine the Accuracy of an Alternative Diagnostic Test when It Is Actually Better than the Reference Tests: A Re-Evaluation of Diagnostic Tests for Scrub Typhus Using Bayesian LCMs

scientific article published on 29 May 2015

Human Infection with Burkholderia thailandensis, China, 2013.

scientific article published in May 2018

Human immune responses to Burkholderia pseudomallei characterized by protein microarray analysis

scientific article

Impaired TLR5 functionality is associated with survival in melioidosis

scientific article published on 27 February 2013

Improved characterisation of MRSA transmission using within-host bacterial sequence diversity

scientific article published on 08 October 2019

Improved culture-based detection and quantification of Burkholderia pseudomallei from soil

scientific article

Increasing incidence of hospital-acquired and healthcare-associated bacteremia in northeast Thailand: a multicenter surveillance study

scientific article

Increasing incidence of human melioidosis in Northeast Thailand

scientific article

Independent association between rate of clearance of infection and clinical outcome of HIV-associated cryptococcal meningitis: analysis of a combined cohort of 262 patients

scientific article published in September 2009

Infection with Burkholderia pseudomallei - immune correlates of survival in acute melioidosis

scientific article published on 22 September 2017

Intensity of exposure and incidence of melioidosis in Thai children

scientific article published in December 2008

Lack of correlation of Burkholderia pseudomallei quantities in blood, urine, sputum and pus.

scientific article published on July 2009

Leapfrogging laboratories: the promise and pitfalls of high-tech solutions for antimicrobial resistance surveillance in low-income settings

scientific article published on 01 December 2020

Leptospira species in floodwater during the 2011 floods in the Bangkok Metropolitan Region, Thailand

scientific article published on 03 September 2013

Long-term survival after intensive care unit discharge in Thailand: a retrospective study

scientific article

Loop-mediated isothermal amplification method targeting the TTS1 gene cluster for detection of Burkholderia pseudomallei and diagnosis of melioidosis

scientific article

Maintenance of leptospira species in leptospira Vanaporn Wuthiekanun agar

scientific article published on 24 September 2014

Management and outcomes of severe dengue patients presenting with sepsis in a tropical country

scientific article (publication date: 24 April 2017)

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for the identification of Burkholderia pseudomallei from Asia and Australia and differentiation between Burkholderia species

scientific article published on 6 April 2017

Melioidosis

Melioidosis

Melioidosis caused by Burkholderia pseudomallei in drinking water, Thailand, 2012.

scientific article published on February 2014

Melioidosis diagnostic workshop, 2013.

scientific article published in February 2015

Melioidosis in Africa: should we be looking more closely?

scientific article

Melioidosis in Thailand: Present and Future.

scientific article published on 8 April 2018

Melioidosis in animals, Thailand, 2006-2010.

scientific article published in February 2012

Melioidosis vaccines: a systematic review and appraisal of the potential to exploit biodefense vaccines for public health purposes

scientific article

Melioidosis: a clinical overview

scientific article published on 09 May 2011

Microevolution of Burkholderia pseudomallei during an acute infection

scientific article

Misidentification of Burkholderia pseudomallei as Acinetobacter species in northern Thailand

scientific article published in January 2019

Molecular confirmation of co-infection by pathogenic Leptospira spp. and Orientia tsutsugamushi in patients with acute febrile illness in Thailand

scientific article

Molecular detection and speciation of pathogenic Leptospira spp. in blood from patients with culture-negative leptospirosis

scientific article

Monoclonal antibody-based immunofluorescence microscopy for the rapid identification of Burkholderia pseudomallei in clinical specimens

scientific article

Mortality attributable to seasonal influenza A and B infections in Thailand, 2005-2009: a longitudinal study

scientific article published on 20 April 2015

Multiple phylogenetically-diverse, differentially-virulent Burkholderia pseudomallei isolated from a single soil sample collected in Thailand

scientific article published on 10 February 2022

Multitarget Quantitative PCR Improves Detection and Predicts Cultivability of the Pathogen Burkholderia pseudomallei

scientific article published on 10 February 2017

New insights from the 7th World Melioidosis Congress 2013.

scientific article

Open-label randomized trial of oral trimethoprim-sulfamethoxazole, doxycycline, and chloramphenicol compared with trimethoprim-sulfamethoxazole and doxycycline for maintenance therapy of melioidosis

scientific article

Optimal Cutoff Titers for Indirect Immunofluorescence Assay for Diagnosis of Scrub Typhus

scientific article published on 9 September 2015

Optimal Cutoff and Accuracy of an IgM Enzyme-Linked Immunosorbent Assay for Diagnosis of Acute Scrub Typhus in Northern Thailand: an Alternative Reference Method to the IgM Immunofluorescence Assay

scientific article published on 23 March 2016

Optimization of culture of Leptospira from humans with leptospirosis

scientific article published on 14 February 2007

Pan-drug-resistant and biofilm-producing strain of : first report of melioidosis from a diabetic patient in Yogyakarta, Indonesia [Letter]

scientific article published on 18 April 2019

Pathogenicity of high-dose enteral inoculation of Burkholderia pseudomallei to mice

scientific article

Patterns of organ involvement in recurrent melioidosis.

scientific article published on August 2009

Pediatric suppurative parotitis in Cambodia between 2007 and 2011.

scientific article published in August 2012

Phenotypic and functional characterization of human memory T cell responses to Burkholderia pseudomallei

scientific article

Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis

scientific article

Presence of B. thailandensis and B. thailandensis expressing B. pseudomallei-like capsular polysaccharide in Thailand, and their associations with serological response to B. pseudomallei

scientific article

Presence of Burkholderia pseudomallei in Soil and Paddy Rice Water in a Rice Field in Northeast Thailand, but Not in Air and Rainwater

scientific article

Prevalence of melioidosis in patients with suspected pulmonary tuberculosis and sputum smear negative for acid-fast bacilli in northeast Thailand

scientific article

Prospective clinical evaluation of the accuracy of 16S rRNA real-time PCR assay for the diagnosis of melioidosis.

scientific article

Prospective evaluation of a rapid immunochromogenic cassette test for the diagnosis of melioidosis in northeast Thailand

scientific article

Prospective observational study of the frequency and features of intra-abdominal abscesses in patients with melioidosis in northeast Thailand

scientific article

Proteomic analysis of colony morphology variants of Burkholderia pseudomallei defines a role for the arginine deiminase system in bacterial survival

scientific article published on 28 October 2011

Public awareness of melioidosis in Thailand and potential use of video clips as educational tools

scientific article

Quality controls for antimicrobial disk diffusion testing on Leptospira Vanaporn Wuthiekanun agar

scientific article

Quantitation of B. Pseudomallei in clinical samples.

scientific article published on November 2007

Rapid design and fielding of four diagnostic technologies in Sierra Leone, Thailand, Peru, and Australia: Successes and challenges faced introducing these biosensors

article

Rapid detection of Burkholderia pseudomallei in blood cultures using a monoclonal antibody-based immunofluorescent assay

scientific article

Rapid immunofluorescence microscopy for diagnosis of melioidosis

scientific article

Rapid isolation and susceptibility testing of Leptospira spp. using a new solid medium, LVW agar

scientific article published on 31 October 2012

Relationship of cerebrospinal fluid pressure, fungal burden and outcome in patients with cryptococcal meningitis undergoing serial lumbar punctures

scientific article published in March 2009

Repeat blood culture positive for B. pseudomallei indicates an increased risk of death from melioidosis ⬇️

scientific article

Risk factors for recurrent melioidosis in northeast Thailand

scientific article

Role and significance of quantitative urine cultures in diagnosis of melioidosis

scientific article

Sensitivity and specificity of a lateral flow immunoassay (LFI) in serum samples for diagnosis of melioidosis

scientific article published on 01 December 2018

Short report: Failure of Burkholderia pseudomallei to grow in an automated blood culture system

scientific article published on 13 October 2014

Simultaneous infection with more than one strain of Burkholderia pseudomallei is uncommon in human melioidosis

scientific article

Soil Nutrient Depletion Is Associated with the Presence of Burkholderia pseudomallei

scientific article published on 30 September 2016

Staphylococcus aureus bacteraemia in a tropical setting: patient outcome and impact of antibiotic resistance

scientific article

Strategies to Reduce Mortality from Bacterial Sepsis in Adults in Developing Countries

scientific article

Subpopulations of Staphylococcus aureus clonal complex 121 are associated with distinct clinical entities

scientific article

Surveillance and Epidemiology of Drug Resistant Infections Consortium (SEDRIC): Supporting the transition from strategy to action.

scientific article

Survey of antimicrobial resistance in clinical Burkholderia pseudomallei isolates over two decades in Northeast Thailand

scientific article published on 29 August 2011

Susceptibility of Clinical Isolates of Burkholderia pseudomallei to a Lipid A Biosynthesis Inhibitor

scientific article

Systematic review and consensus guidelines for environmental sampling of Burkholderia pseudomallei

scientific article (publication date: 2013)

T-Cell Responses Are Associated with Survival in Acute Melioidosis Patients

scientific article published on 23 October 2015

The Effects of Signal Erosion and Core Genome Reduction on the Identification of Diagnostic Markers

scientific article

The epidemiology of pediatric bone and joint infections in Cambodia, 2007-11

scientific article published on 13 September 2012

The role of NOD2 in murine and human melioidosis

scientific article

The value of intermittent point-prevalence surveys of healthcare-associated infections for evaluating infection control interventions at Angkor Hospital for Children, Siem Reap, Cambodia ⬇️

scientific article published on February 14, 2013

Thrombocytopenia Impairs Host Defense Against Burkholderia pseudomallei (Melioidosis)

scientific article published on 01 January 2019

Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis)

scientific article (publication date: 31 July 2007)

Toxicity of Amphotericin B Deoxycholate-Based Induction Therapy in Patients with HIV-Associated Cryptococcal Meningitis

scientific article published on 8 September 2015

Trimethoprim-sulfamethoxazole versus trimethoprim-sulfamethoxazole plus doxycycline as oral eradicative treatment for melioidosis (MERTH): a multicentre, double-blind, non-inferiority, randomised controlled trial

scientific article

Trimethoprim/sulfamethoxazole resistance in clinical isolates of Burkholderia pseudomallei

scientific article

Trimethoprim/sulfamethoxazole resistance in clinical isolates of Burkholderia pseudomallei from Thailand

scientific article published on 16 February 2015

Two randomized controlled trials of ceftazidime alone versus ceftazidime in combination with trimethoprim-sulfamethoxazole for the treatment of severe melioidosis

scientific article

Using a web-based application to define the accuracy of diagnostic tests when the gold standard is imperfect

scientific article

Utility of SOFA score, management and outcomes of sepsis in Southeast Asia: a multinational multicenter prospective observational study

scientific article published on 14 February 2018

Utility of a Lateral Flow Immunoassay (LFI) to Detect Burkholderia pseudomallei in Soil Samples

scientific article

Utility of qSOFA and modified SOFA in severe malaria presenting as sepsis

scientific article published on 09 October 2019

Variable presentation of neurological melioidosis in Northeast Thailand

scientific article published on July 2007

What's wrong in the control of antimicrobial resistance in critically ill patients from low- and middle-income countries?

scientific article published on 13 April 2017

Within-host evolution of Burkholderia pseudomallei in four cases of acute melioidosis

scientific article

Workshop on treatment of and postexposure prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010

scientific article published on December 2012

Zero tolerance for healthcare-associated MRSA bacteraemia: is it realistic?

scientific article

“AMR Dialogues”: a public engagement initiative to shape policies and solutions on antimicrobial resistance (AMR) in Thailand

scientific article published on 07 April 2022

“AMR Dialogues”: a public engagement initiative to shape policies and solutions on antimicrobial resistance (AMR) in Thailand

scientific article published on 26 July 2021

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