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List of works by Salvatore Siena

A Comprehensive PDX Gastric Cancer Collection Captures Cancer Cell-Intrinsic Transcriptional MSI Traits

scientific article published on 04 October 2019

A Genomic Analysis Workflow for Colorectal Cancer Precision Oncology

scientific article published on 07 March 2019

A Multicenter Phase 2 Study of AMG 337 in Patients With -Amplified Gastric/Gastroesophageal Junction/Esophageal Adenocarcinoma and Other Solid Tumors

scientific article published on 26 October 2018

A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin

scientific article published on 12 December 2019

A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer

scientific article

A phase 1b/2 study of the BRAF inhibitor encorafenib plus the MEK inhibitor binimetinib in patients with BRAF V600E/K-mutant solid tumors

scientific article published on 15 July 2020

A phase II randomized multicenter trial of gefitinib plus FOLFIRI and FOLFIRI alone in patients with metastatic colorectal cancer.

scientific article published on 30 July 2008

Absence of c-Kit and members of the epidermal growth factor receptor family in refractory germ cell cancer

scientific article published on 01 June 2003

Acquired RAS or EGFR mutations and duration of response to EGFR blockade in colorectal cancer.

scientific article published on 8 December 2016

Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer.

scientific article published on 6 November 2015

Acquired resistance to EGFR-targeted therapies in colorectal cancer

scientific article published on 14 May 2014

Adaptive mutability of colorectal cancers in response to targeted therapies

scientific article published on 07 November 2019

Adjuvant chemotherapy of pT1a and pT1b breast carcinoma: results from the NEMESI study

scientific article

Adoptive transfer of allogeneic Epstein-Barr virus (EBV)-specific cytotoxic T cells with in vitro antitumor activity boosts LMP2-specific immune response in a patient with EBV-related nasopharyngeal carcinoma.

scientific article published in January 2004

Advanced non-small cell lung cancer management in patients progressing after first-line treatment: results of the cross-sectional phase of the Italian LIFE observational study

scientific article published on 6 June 2014

Allogeneic blood stem cell transplantation after a reduced-intensity, preparative regimen: a pilot study in patients with refractory malignancies

scientific article

Allogeneic haematopoietic stem cell transplantation for metastatic renal carcinoma in Europe

scientific article published on 28 April 2006

Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer

scientific article

An analysis of the treatment effect of panitumumab on overall survival from a phase 3, randomized, controlled, multicenter trial (20020408) in patients with chemotherapy refractory metastatic colorectal cancer.

scientific article published on 27 April 2013

An expanded access program of erlotinib (Tarceva) in patients with advanced non-small cell lung cancer (NSCLC): data report from Italy

scientific article

Analysis of circulating DNA and protein biomarkers to predict the clinical activity of regorafenib and assess prognosis in patients with metastatic colorectal cancer: a retrospective, exploratory analysis of the CORRECT trial

scientific article published on 13 July 2015

Anti-EGFR monoclonal antibodies in the treatment of non-small cell lung cancer.

scientific article

Antitumor effect of allogeneic hematopoietic SCT in metastatic medulloblastoma

scientific article published on 31 March 2008

Aspirin for colorectal cancer with PIK3CA mutations: the rising of the oldest targeted therapy?

scientific article published on July 2013

Assessment of a HER2 scoring system for colorectal cancer: results from a validation study

scientific article published on 09 October 2015

Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab

scientific article

Association of progression-free survival with patient-reported outcomes and survival: results from a randomised phase 3 trial of panitumumab.

scientific article published on 27 November 2007

Association of progression-free survival, overall survival, and patient-reported outcomes by skin toxicity and KRAS status in patients receiving panitumumab monotherapy.

scientific article

Author Correction: Exploratory analyses assessing the impact of early tumour shrinkage and depth of response on survival outcomes in patients with RAS wild-type metastatic colorectal cancer receiving treatment in three randomised panitumumab trials.

scientific article published on 15 February 2018

BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis

scientific article published on 7 July 2015

BRAF-mutant Transcriptional Subtypes Predict Outcome of Combined BRAF, MEK, and EGFR Blockade with Dabrafenib, Trametinib, and Panitumumab in Patients with Colorectal Cancer

scientific article published on 11 February 2020

Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer

scientific article published on 08 September 2009

Blockade of EGFR and MEK intercepts heterogeneous mechanisms of acquired resistance to anti-EGFR therapies in colorectal cancer

scientific article published in February 2014

Cell therapy of stage IV nasopharyngeal carcinoma with autologous Epstein-Barr virus-targeted cytotoxic T lymphocytes.

scientific article

Cetuximab for treatment of metastatic colorectal cancer

scientific article published on 01 June 2006

Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer

scientific article (publication date: 22 July 2004)

Cetuximab plus gemcitabine and cisplatin compared with gemcitabine and cisplatin alone in patients with advanced pancreatic cancer: a randomised, multicentre, phase II trial

scientific article published in January 2008

Cetuximab plus irinotecan in heavily pretreated metastatic colorectal cancer progressing on irinotecan: MABEL Study.

scientific article published on 14 October 2008

Clinical utilisation of human haematopoietic progenitors elicited in peripheral blood by recombinant human granulocyte colony-stimulating factor (rHuG-CSF).

scientific article

Clonal evolution and KRAS-MET coamplification during secondary resistance to EGFR-targeted therapy in metastatic colorectal cancer.

scientific article

Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.

scientific article

Combined BRAF, EGFR, and MEK Inhibition in Patients with BRAFV600E-Mutant Colorectal Cancer

scientific article published on 5 February 2018

Combined Low Densities of FoxP3+ and CD3+ Tumor-Infiltrating Lymphocytes Identify Stage II Colorectal Cancer at High Risk of Progression

scientific article published on 25 February 2019

Detection of circulating tumor DNA in early- and late-stage human malignancies

scientific article (publication date: 19 February 2014)

Digital PCR assessment of MGMT promoter methylation coupled with reduced protein expression optimises prediction of response to alkylating agents in metastatic colorectal cancer patients.

scientific article published on 16 December 2016

Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer.

scientific article published on 25 June 2015

Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer

scientific article

Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study.

scientific article

Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial

scientific article

Dynamic molecular analysis and clinical correlates of tumor evolution within a phase II trial of panitumumab-based therapy in metastatic colorectal cancer.

scientific article published on 4 September 2017

EGFR FISH in colorectal cancer: what is the current reality?

scientific article

EGFR blockade reverts resistance to KRAS G12C inhibition in colorectal cancer

scientific article published on 19 May 2020

Early-onset colorectal cancer in young individuals

scientific article published on 22 December 2018

Effect of KRAS and BRAF Mutations on Survival of Metastatic Colorectal Cancer After Liver Resection: A Systematic Review and Meta-Analysis

scientific article published on 25 January 2017

Effect of Primary Tumor Location on Second- or Later-line Treatment Outcomes in Patients With RAS Wild-type Metastatic Colorectal Cancer and All Treatment Lines in Patients With RAS Mutations in Four Randomized Panitumumab Studies

scientific article published on 08 March 2018

Effects of Cancer Therapy Targeting Vascular Endothelial Growth Factor Receptor on Central Blood Pressure and Cardiovascular System

scientific article

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

scientific article

Efficacy of Sym004 in Patients With Metastatic Colorectal Cancer With Acquired Resistance to Anti-EGFR Therapy and Molecularly Selected by Circulating Tumor DNA Analyses: A Phase 2 Randomized Clinical Trial

scientific article published on 8 February 2018

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

scientific article

Entrectinib approval by EMA reinforces options for ROS1 and tumour agnostic NTRK targeted cancer therapies

scientific article published on 01 September 2020

Entrectinib for the treatment of metastatic NSCLC: safety and efficacy

scientific article published on 08 April 2020

Epidermal growth factor receptor gene copy number and clinical outcome of metastatic colorectal cancer treated with panitumumab

scientific article published on 01 August 2007

Epigenetic inactivation of the BRCA1 interactor SRBC and resistance to oxaliplatin in colorectal cancer.

scientific article

Epigenomic landscape of human colorectal cancer unveils an aberrant core of pan-cancer enhancers orchestrated by YAP/TAZ

scientific article published on 20 April 2021

Erratum to: Integrated molecular dissection of the epidermal growth factor receptor (EGFR) oncogenic pathway to predict response to EGFR-targeted monoclonal antibodies in metastatic colorectal cancer

scholarly article published in Targeted oncology

Erratum: Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients

scientific article published on 01 July 2015

Evidence of graft-versus-tumour effect following allogeneic haematopoietic stem cell transplantation in renal cancer other than clear cell type

scientific article published on 01 November 2004

Ex vivo generation and expansion of anti-tumor cytotoxic T-cell lines derived from patients or their HLA-identical sibling.

scientific article published on May 2004

Exploratory analyses assessing the impact of early tumour shrinkage and depth of response on survival outcomes in patients with RAS wild-type metastatic colorectal cancer receiving treatment in three randomised panitumumab trials

scientific article published on 28 October 2017

Exploring the links between cancer and placenta development

article

Feasibility and safety of adoptive immunotherapy with ex vivo-generated autologous, cytotoxic T lymphocytes in patients with solid tumor

scientific article published on 23 September 2011

Final results from PRIME: randomized phase III study of panitumumab with FOLFOX4 for first-line treatment of metastatic colorectal cancer

scientific article

First-line erlotinib followed by second-line cisplatin-gemcitabine chemotherapy in advanced non-small-cell lung cancer: the TORCH randomized trial

scientific article

First-line single-agent cetuximab in patients with advanced colorectal cancer

scientific article published on 10 December 2007

Gemcitabine plus Cisplatin versus Gemcitabine plus Carboplatin as First-Line Chemotherapy in Advanced Transitional Cell Carcinoma of the Urothelium: Results of a Randomized Phase 2 Trial

scientific article published on 26 December 2006

Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study

scientific article published in May 2005

Granulocyte-macrophage colony-stimulating factor to harvest circulating haemopoietic stem cells for autotransplantation

scientific article published on 01 September 1989

HER1/EGFR inhibitor-associated rash: future directions for management and investigation outcomes from the HER1/EGFR inhibitor rash management forum

scientific article

HER2 Positivity Predicts Unresponsiveness to EGFR-Targeted Treatment in Metastatic Colorectal Cancer

scientific article published on 05 April 2019

Haematopoietic stem cell transplantation in adult soft-tissue sarcoma: an analysis from the European Society for Blood and Marrow Transplantation

scientific article published on 01 October 2020

High dose chemotherapy with autologous hematopoietic stem cell support for solid tumors other than breast cancer in adults.

scientific article

High-Dose Chemotherapy and Autologous Bone Marrow Transplantation Compared with MACOP-B in Aggressive B-Cell Lymphoma

scientific article published on 01 May 1997

High-dose sequential chemotherapy (HDS) versus PEB chemotherapy as first-line treatment of patients with poor prognosis germ-cell tumors: mature results of an Italian randomized phase II study

scientific article published on 24 October 2014

Human Epidermal Growth Factor Receptor 2 as a Molecular Biomarker for Metastatic Colorectal Cancer.

scientific article published on 19 October 2017

Immunomodulatory effects in a phase II study of lenalidomide combined with cetuximab in refractory KRAS-mutant metastatic colorectal cancer patients

scientific article (publication date: 2013)

Impact of early tumour shrinkage and resection on outcomes in patients with wild-type RAS metastatic colorectal cancer

scientific article published on 05 May 2015

Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth.

scientific article published on 29 November 2017

Incidence of human cytomegalovirus infection in patients with refractory solid tumors receiving nonmyeloablative allogeneic stem cell transplants versus recipients of standard SCT for hematologic malignancies.

scientific article published in June 2005

Increased incidence of colon cancer among individuals younger than 50 years: A 17 years analysis from the cancer registry of the municipality of Milan, Italy

scientific article published on 18 April 2019

Integrated molecular dissection of the epidermal growth factor receptor (EGFR) [corrected] oncogenic pathway to predict response to EGFR-targeted monoclonal antibodies in metastatic colorectal cancer.

scientific article published on March 2010

Integrating liquid biopsies into the management of cancer

scientific article published on 2 March 2017

Iron supplement in cancer patients receiving erythropoietin

scientific article published on 01 November 2004

Iron supplementation and erythropoiesis-stimulatory agents in the treatment of cancer anemia.

scientific article published on March 2009

Iron supplementation during treatment with erythropoiesis-stimulating agents for cancer-related anemia.

scientific article published on 29 September 2008

KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy

scientific article

KRAS mutations testing in colorectal carcinoma patients in Italy: from guidelines to external quality assessment

scientific article (publication date: 2011)

Large-scale collection of circulating haematopoietic progenitors in cancer patients treated with high-dose cyclophosphamide and recombinant human GM-CSF.

scientific article

Linitis Plastica of the Rectum As a Clinical Presentation of Metastatic Lobular Carcinoma of the Breast

scientific article published on 30 June 2014

Lipid-lowering therapy of everolimus-related severe hypertriglyceridaemia in a pancreatic neuroendocrine tumour (pNET)

scientific article published on 21 July 2017

Long-term hematopoietic culture-initiating cells are more abundant in mobilized peripheral blood grafts than in bone marrow but have a more limited ex vivo expansion potential.

scientific article published in January 1996

Magnetic resonance imaging as an early indicator of clinical outcome in patients with metastatic colorectal carcinoma treated with cetuximab or panitumumab

scientific article

Malignant peritoneal mesothelioma-Results from the International Expanded Access Program using pemetrexed alone or in combination with a platinum agent.

scientific article

Malignant peritoneal mesothelioma: a multicenter study on 81 cases.

scientific article published on 27 July 2009

Massively parallel tumor multigene sequencing to evaluate response to panitumumab in a randomized phase III study of metastatic colorectal cancer

scientific article

Mobilization of peripheral blood progenitor cells for autografting: chemotherapy and G-CSF or GM-CSF

scientific article published on 01 March 1999

Molecular Landscape of Acquired Resistance to Targeted Therapy Combinations in BRAF-Mutant Colorectal Cancer

scientific article published on 16 June 2016

Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer

scientific article

Multi-determinants analysis of molecular alterations for predicting clinical benefit to EGFR-targeted monoclonal antibodies in colorectal cancer

scientific article

Mutant KRAS codon 12 and 13 alleles in patients with metastatic colorectal cancer: assessment as prognostic and predictive biomarkers of response to panitumumab

scientific article published on 26 November 2012

Mutations of KRAS and BRAF in primary and matched metastatic sites of colorectal cancer

scientific article published on 01 September 2008

NTRK gene fusions as novel targets of cancer therapy across multiple tumour types

scientific article

Novel CAD-ALK gene rearrangement is drugable by entrectinib in colorectal cancer

scientific article

Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies.

scientific article

Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer

scientific article

Optimising management of neutropenia and anaemia in cancer chemotherapy-advances in cytokine therapy.

scientific article published on October 2003

Overall survival improvement in patients with lung cancer and bone metastases treated with denosumab versus zoledronic acid: subgroup analysis from a randomized phase 3 study

scientific article published on 01 December 2012

Overcoming dynamic molecular heterogeneity in metastatic colorectal cancer: Multikinase inhibition with regorafenib and the case of rechallenge with anti-EGFR.

scientific article published on 29 October 2016

Oxaliplatin Immune-Induced Syndrome Occurs With Cumulative Administration and Rechallenge: Single Institution Series and Systematic Review Study.

scientific article

PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies

scientific article

Panitumumab in combination with gemcitabine and oxaliplatin does not prolong survival in wild-type KRAS advanced biliary tract cancer: A randomized phase 2 trial (Vecti-BIL study).

scientific article published on 5 November 2015

Panitumumab in combination with infusional oxaliplatin and oral capecitabine for conversion therapy in patients with colon cancer and advanced liver metastases ⬇️

scientific article published on July 18, 2013

Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer

scientific article

Parallel Evaluation of Circulating Tumor DNA and Circulating Tumor Cells in Metastatic Colorectal Cancer

scientific article published in November 2017

Patient-Derived Xenografts and Matched Cell Lines Identify Pharmacogenomic Vulnerabilities in Colorectal Cancer

scientific article published on 02 August 2019

Peripheral blood expansion of early progenitor cells after high-dose cyclophosphamide and rhGM-CSF ⬇️

scientific article published on January 1, 1991

Pertuzumab and trastuzumab emtansine in patients with HER2-amplified metastatic colorectal cancer: the phase II HERACLES-B trial

scientific article published on 01 September 2020

Phase II multicenter, uncontrolled trial of sorafenib in patients with metastatic breast cancer

scientific article published in August 2009

Phase II open-label study to assess efficacy and safety of lenalidomide in combination with cetuximab in KRAS-mutant metastatic colorectal cancer

scientific article (publication date: 2013)

Phase II study of cetuximab in combination with cisplatin and docetaxel in patients with untreated advanced gastric or gastro-oesophageal junction adenocarcinoma (DOCETUX study).

scientific article published on 22 September 2009

Pilot evaluation of scrambler therapy for pain induced by bone and visceral metastases and refractory to standard therapies.

scientific article published on 26 September 2015

Plasma HER2 (ERBB2) Copy Number Predicts Response to HER2-targeted Therapy in Metastatic Colorectal Cancer

scientific article published on 26 February 2019

Plasticity of Resistance and Sensitivity to Anti-Epidermal Growth Factor Receptor Inhibitors in Metastatic Colorectal Cancer.

scientific article published on 6 April 2017

Pooled Analysis of Clinical Outcome of Patients with Chemorefractory Metastatic Colorectal Cancer Treated within Phase I/II Clinical Studies Based on Individual Biomarkers of Susceptibility: A Single-Institution Experience

scientific article

Positron emission tomography response evaluation from a randomized phase III trial of weekly nab-paclitaxel plus gemcitabine versus gemcitabine alone for patients with metastatic adenocarcinoma of the pancreas.

scientific article published on 22 January 2016

Present results and perspectives of allogeneic non-myeloablative hematopoietic stem cell transplantation for treatment of human solid tumors.

scientific article

Primary tumor sidedness has an impact on prognosis and treatment outcome in metastatic colorectal cancer: results from two randomized first-line panitumumab studies.

scientific article published on 25 April 2017

Prognostic factors for survival in patients with advanced renal cell carcinoma undergoing nonmyeloablative allogeneic stem cell transplantation.

scientific article

Prognostic significance of K-Ras mutation rate in metastatic colorectal cancer patients.

scientific article published on 19 August 2015

Promoter CpG island hypermethylation of the DNA repair enzyme MGMT predicts clinical response to dacarbazine in a phase II study for metastatic colorectal cancer.

scientific article

Quality of life analysis of TORCH, a randomized trial testing first-line erlotinib followed by second-line cisplatin/gemcitabine chemotherapy in advanced non-small-cell lung cancer

scientific article published in December 2012

Radiologic and Genomic Evolution of Individual Metastases during HER2 Blockade in Colorectal Cancer

scientific article published on 01 July 2018

Radiological imaging markers predicting clinical outcome in patients with metastatic colorectal carcinoma treated with regorafenib: post hoc analysis of the CORRECT phase III trial (RadioCORRECT study).

scientific article

Randomized Phase II Trial of Seribantumab in Combination With Paclitaxel in Patients With Advanced Platinum-Resistant or -Refractory Ovarian Cancer.

scientific article published on 23 October 2016

Randomized trial of intravenous iron supplementation in patients with chemotherapy-related anemia without iron deficiency treated with darbepoetin alpha.

scientific article published in April 2008

Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study

scientific article (publication date: November 2010)

Reduced intensity stem cell transplantation for advanced soft tissue sarcomas in adults: a retrospective analysis of the European Group for Blood and Marrow Transplantation

scientific article published on 01 March 2007

Regorafenib for metastatic colorectal cancer

Regorafenib in metastatic colorectal cancer.

scientific article

Relationships between tumour response and primary tumour location, and predictors of long-term survival, in patients with RAS wild-type metastatic colorectal cancer receiving first-line panitumumab therapy: retrospective analyses of the PRIME and PE

Reliance upon ancestral mutations is maintained in colorectal cancers that heterogeneously evolve during targeted therapies.

scientific article

Resistance to anti-EGFR therapy in colorectal cancer: from heterogeneity to convergent evolution

scientific article published on 07 October 2014

Retreatment with anti-EGFR monoclonal antibodies in metastatic colorectal cancer: Systematic review of different strategies

scientific article published on 27 December 2018

Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1).

scientific article published on 9 February 2017

Sensitivity to Entrectinib Associated With a Novel LMNA-NTRK1 Gene Fusion in Metastatic Colorectal Cancer

scientific article

Sequential HER2 blockade as effective therapy in chemorefractory, HER2 gene-amplified, RAS wild-type, metastatic colorectal cancer: learning from a clinical case.

scientific article published on 10 January 2018

Skin toxicity and quality of life during treatment with panitumumab for RAS wild-type metastatic colorectal carcinoma: results from three randomised clinical trials

scientific article published on 15 April 2016

Sorafenib does not improve efficacy of chemotherapy in advanced pancreatic cancer: A GISCAD randomized phase II study

scientific article published on 02 November 2013

Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial

scientific article

Standardisation of EGFR FISH in colorectal cancer: results of an international interlaboratory reproducibility ring study.

scientific article published on 30 November 2011

Sunitinib treatment in pediatric patients with advanced GIST following failure of imatinib.

scientific article

Survival Outcomes in Patients With RAS Wild Type Metastatic Colorectal Cancer Classified According to Köhne Prognostic Category and BRAF Mutation Status

scientific article published on 28 September 2017

Survival of adults treated for medulloblastoma using paediatric protocols.

scientific article published in June 2005

T-cell therapy for EBV-associated nasopharyngeal carcinoma: preparative lymphodepleting chemotherapy does not improve clinical results.

scientific article

TRKA expression and NTRK1 gene copy number across solid tumours.

scientific article

Targeted therapies: how personal should we go?

scientific article

Targeting the human epidermal growth factor receptor 2 (HER2) oncogene in colorectal cancer.

scientific article

The Evolutionary Landscape of Treatment for <i>BRAF<sup>V600E</sup></i> Mutant Metastatic Colorectal Cancer

scientific article published on 04 January 2021

The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition.

scientific article

The genomic landscape of response to EGFR blockade in colorectal cancer.

scientific article published on 30 September 2015

The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets

scientific article published on 30 April 2015

Therapeutic implications of resistance to molecular therapies in metastatic colorectal cancer.

scientific article

Total body irradiation and high-dose melphalan with bone marrow transplantation at Istituto Nazionale Tumori, Milan, Italy

article

Toxicity of oxaliplatin rechallenge in metastatic colorectal cancer

scientific article published on 01 October 2018

Tracking a CAD-ALK gene rearrangement in urine and blood of a colorectal cancer patient treated with an ALK inhibitor.

scientific article published on 24 March 2017

Transfusion of platelet concentrates cryopreserved with ThromboSol plus low-dose dimethylsulphoxide in patients with severe thrombocytopenia: a pilot study.

scientific article

Translational challenges from the 2014 Gastrointestinal Cancers Symposium: toward a true tailored therapy through effective research

scientific article

Tropisetron plus haloperidol to ameliorate nausea and vomiting associated with high-dose alkylating agent cancer chemotherapy

scientific article published on 01 January 1991

Tumor Heterogeneity and Lesion-Specific Response to Targeted Therapy in Colorectal Cancer

scientific article

Tumor MGMT promoter hypermethylation changes over time limit temozolomide efficacy in a phase II trial for metastatic colorectal cancer

scientific article published on 24 February 2016

Vitamin C Restricts the Emergence of Acquired Resistance to EGFR-Targeted Therapies in Colorectal Cancer

scientific article published on 14 March 2020

Whole exome sequencing analysis of urine trans-renal tumour DNA in metastatic colorectal cancer patients

scientific article published on 01 November 2019

Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer

scientific article

Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer

scientific article

nab-Paclitaxel plus gemcitabine for metastatic pancreatic cancer: long-term survival from a phase III trial.

scientific article published on 31 January 2015

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