List of works - Adrianus Henricus Maria Geurts van Kessel

12p-amplicon structure analysis in testicular germ cell tumors of adolescents and adults by array CGH.

scientific article published in October 2003

A germline homozygous mutation in the base-excision repair gene NTHL1 causes adenomatous polyposis and colorectal cancer

scientific article

A molecular inversion probe-based next-generation sequencing panel to detect germline mutations in Chinese early-onset colorectal cancer patients

scientific article

A new chromosome 17q21.31 microdeletion syndrome associated with a common inversion polymorphism.

scientific article

Acquired mutations in TET2 are common in myelodysplastic syndromes

scientific article

Array-based comparative genomic hybridization for the genomewide detection of submicroscopic chromosomal abnormalities

scientific article

BTG1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia

scientific article published on 30 March 2010

CDK19 is disrupted in a female patient with bilateral congenital retinal folds, microcephaly and mild mental retardation

scientific article

Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases

scientific article

Chromosomal breakpoint mapping by arrayCGH using flow-sorted chromosomes

scientific article published on November 2003

Chromosome 3 translocations and familial renal cell cancer

scientific article

Clinical and cytogenetic characterization of 13 Dutch patients with deletion 9p syndrome: Delineation of the critical region for a consensus phenotype

scientific article published in June 2008

Complex chromosome 17p rearrangements associated with low-copy repeats in two patients with congenital anomalies

scientific article published on 25 April 2007

Definition of a critical region on chromosome 18 for congenital aural atresia by arrayCGH

scientific article

Deleterious Germline BLM Mutations and the Risk for Early-onset Colorectal Cancer

scientific article

Detection of chromosome aneuploidies in chorionic villus samples by multiplex ligation-dependent probe amplification

scientific article published on 12 December 2008

Diagnostic genome profiling in mental retardation

scientific article

Disruption of a novel MFS transporter gene, DIRC2, by a familial renal cell carcinoma-associated t(2;3)(q35;q21).

scientific article

EPCAM deletion carriers constitute a unique subgroup of Lynch syndrome patients

scientific article published on June 2013

Fusion of the SUMO/Sentrin-specific protease 1 gene SENP1 and the embryonic polarity-related mesoderm development gene MESDC2 in a patient with an infantile teratoma and a constitutional t(12;15)(q13;q25).

scientific article

Genome-wide array-based comparative genomic hybridization reveals multiple amplification targets and novel homozygous deletions in pancreatic carcinoma cell lines

scientific article published on May 2004

Genome-wide copy number profiling on high-density bacterial artificial chromosomes, single-nucleotide polymorphisms, and oligonucleotide microarrays: a platform comparison based on statistical power analysis

scientific article

Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene

scientific article

Genomic microarrays in mental retardation: a practical workflow for diagnostic applications

scientific article published on March 2009

Genotype–phenotype mapping of chromosome 18q deletions by high-resolution array CGH: An update of the phenotypic map

scientific article published on 01 August 2007

Germ cell tumours in neonates and infants: a distinct subgroup?

scientific article

Germline copy number variation and cancer risk

scientific article published on 08 April 2010

Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1.

scientific article published on 21 December 2008

High resolution profiling of X chromosomal aberrations by array comparative genomic hybridisation.

scientific article published in June 2004

High-resolution DNA copy number and gene expression analyses distinguish chromophobe renal cell carcinomas and renal oncocytomas

scientific article

High-throughput analysis of subtelomeric chromosome rearrangements by use of array-based comparative genomic hybridization

scientific article published on 9 April 2002

Histone deacetylase inhibitors reverse SS18-SSX-mediated polycomb silencing of the tumor suppressor early growth response 1 in synovial sarcoma

scientific article

Holoprosencephaly and preaxial polydactyly associated with a 1.24 Mb duplication encompassing FBXW11 at 5q35.1.

scientific article

Homozygosity mapping in outbred families with mental retardation

scientific article

Identification of Novel Candidate Genes for Early-Onset Colorectal Cancer Susceptibility

scientific article

Identification of androgen-responsive genes that are alternatively regulated in androgen-dependent and androgen-independent rat prostate tumors

scientific article published on July 2005

Identification of candidate predisposing copy number variants in familial and early-onset colorectal cancer patients

scientific article

Identification of disease genes by whole genome CGH arrays

scientific article

Identification of non-recurrent submicroscopic genome imbalances: the advantage of genome-wide microarrays over targeted approaches

scientific article published on 9 January 2008

Identification of prognostic relevant chromosomal abnormalities in chronic lymphocytic leukemia using microarray-based genomic profiling

scientific article published on 09 January 2014

Identification of recurrent chromosomal aberrations in germ cell tumors of neonates and infants using genomewide array-based comparative genomic hybridization

scientific article published on August 2005

Loss of a small region around the PTEN locus is a major chromosome 10 alteration in prostate cancer xenografts and cell lines

scientific article published on March 2004

Mapping of constitutional translocation breakpoints in renal cell cancer patients: identification of KCNIP4 as a candidate gene

scientific article

Microarray analyses reveal strong influence of DNA copy number alterations on the transcriptional patterns in pancreatic cancer: implications for the interpretation of genomic amplifications

scientific article published on March 2005

Molecular characterisation of patients with subtelomeric 22q abnormalities using chromosome specific array-based comparative genomic hybridisation

scientific article

Molecular cytogenetic analysis of clustered sporadic and familial renal cell carcinoma-associated 3q13 approximately q22 breakpoints

scientific article

Mutations in a new member of the chromodomain gene family cause CHARGE syndrome

scientific article

Noonan syndrome, the SOS1 gene and embryonal rhabdomyosarcoma

scientific article published on July 2010

Perivascular epithelioid cell tumor of gastrointestinal tract: case report and review of the literature

scientific article

Predictors and risk model development for menopausal age in fragile X premutation carriers ⬇️

scientific article published on July 1, 2011

Prevalence of germline mutations in the spindle assembly checkpoint gene BUB1B in individuals with early-onset colorectal cancer

scientific article published on 30 May 2016

Rare pathogenic microdeletions and tandem duplications are microhomology-mediated and stimulated by local genomic architecture

scientific article

Recurrent CNVs disrupt three candidate genes in schizophrenia patients

scientific article published on October 2008

Regulation of the MiTF/TFE bHLH-LZ transcription factors through restricted spatial expression and alternative splicing of functional domains

scientific article

Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study

scientific article published on 8 December 2010

Role of gain of 12p in germ cell tumour development

scientific article published in January 2003

The (epi)genetics of human synovial sarcoma

scientific article published on February 2007

The Mitotic Arrest Deficient Protein MAD2B Interacts with the Clathrin Light Chain A during Mitosis ⬇️

scientific article published on November 30, 2010

The Origin and Nature of Tightly Clustered BTG1 Deletions in Precursor B-Cell Acute Lymphoblastic Leukemia Support a Model of Multiclonal Evolution ⬇️

scientific article published on February 16, 2012

The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP

scientific article

The epigenetics of (hereditary) colorectal cancer

scientific article

The mitotic arrest deficient protein MAD2B interacts with the small GTPase RAN throughout the cell cycle

scientific article

The renal cell carcinoma-associated oncogenic fusion protein PRCCTFE3 provokes p21 WAF1/CIP1-mediated cell cycle delay

scientific article

Understanding familial and non-familial renal cell cancer

scientific article

Unraveling genetic predisposition to familial or early onset gastric cancer using germline whole-exome sequencing

scientific article published on 6 September 2017

Upregulation of the transcription factor TFEB in t(6;11)(p21;q13)-positive renal cell carcinomas due to promoter substitution

scientific article

List of works by Adrianus Henricus Maria Geurts van Kessel

12p-amplicon structure analysis in testicular germ cell tumors of adolescents and adults by array CGH.

A germline homozygous mutation in the base-excision repair gene NTHL1 causes adenomatous polyposis and colorectal cancer

A molecular inversion probe-based next-generation sequencing panel to detect germline mutations in Chinese early-onset colorectal cancer patients

A new chromosome 17q21.31 microdeletion syndrome associated with a common inversion polymorphism.

Acquired mutations in TET2 are common in myelodysplastic syndromes

Array-based comparative genomic hybridization for the genomewide detection of submicroscopic chromosomal abnormalities

BTG1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia

CDK19 is disrupted in a female patient with bilateral congenital retinal folds, microcephaly and mild mental retardation

Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases

Chromosomal breakpoint mapping by arrayCGH using flow-sorted chromosomes

Chromosome 3 translocations and familial renal cell cancer

Clinical and cytogenetic characterization of 13 Dutch patients with deletion 9p syndrome: Delineation of the critical region for a consensus phenotype

Complex chromosome 17p rearrangements associated with low-copy repeats in two patients with congenital anomalies

Definition of a critical region on chromosome 18 for congenital aural atresia by arrayCGH

Deleterious Germline BLM Mutations and the Risk for Early-onset Colorectal Cancer

Detection of chromosome aneuploidies in chorionic villus samples by multiplex ligation-dependent probe amplification

Diagnostic genome profiling in mental retardation

Disruption of a novel MFS transporter gene, DIRC2, by a familial renal cell carcinoma-associated t(2;3)(q35;q21).

EPCAM deletion carriers constitute a unique subgroup of Lynch syndrome patients

Fusion of the SUMO/Sentrin-specific protease 1 gene SENP1 and the embryonic polarity-related mesoderm development gene MESDC2 in a patient with an infantile teratoma and a constitutional t(12;15)(q13;q25).

Genome-wide array-based comparative genomic hybridization reveals multiple amplification targets and novel homozygous deletions in pancreatic carcinoma cell lines

Genome-wide copy number profiling on high-density bacterial artificial chromosomes, single-nucleotide polymorphisms, and oligonucleotide microarrays: a platform comparison based on statistical power analysis

Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene

Genomic microarrays in mental retardation: a practical workflow for diagnostic applications

Genotype–phenotype mapping of chromosome 18q deletions by high-resolution array CGH: An update of the phenotypic map

Germ cell tumours in neonates and infants: a distinct subgroup?

Germline copy number variation and cancer risk

Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1.

High resolution profiling of X chromosomal aberrations by array comparative genomic hybridisation.

High-resolution DNA copy number and gene expression analyses distinguish chromophobe renal cell carcinomas and renal oncocytomas

High-throughput analysis of subtelomeric chromosome rearrangements by use of array-based comparative genomic hybridization

Histone deacetylase inhibitors reverse SS18-SSX-mediated polycomb silencing of the tumor suppressor early growth response 1 in synovial sarcoma

Holoprosencephaly and preaxial polydactyly associated with a 1.24 Mb duplication encompassing FBXW11 at 5q35.1.

Homozygosity mapping in outbred families with mental retardation

Identification of Novel Candidate Genes for Early-Onset Colorectal Cancer Susceptibility

Identification of androgen-responsive genes that are alternatively regulated in androgen-dependent and androgen-independent rat prostate tumors

Identification of candidate predisposing copy number variants in familial and early-onset colorectal cancer patients

Identification of disease genes by whole genome CGH arrays

Identification of non-recurrent submicroscopic genome imbalances: the advantage of genome-wide microarrays over targeted approaches

Identification of prognostic relevant chromosomal abnormalities in chronic lymphocytic leukemia using microarray-based genomic profiling

Identification of recurrent chromosomal aberrations in germ cell tumors of neonates and infants using genomewide array-based comparative genomic hybridization

Loss of a small region around the PTEN locus is a major chromosome 10 alteration in prostate cancer xenografts and cell lines

Mapping of constitutional translocation breakpoints in renal cell cancer patients: identification of KCNIP4 as a candidate gene

Microarray analyses reveal strong influence of DNA copy number alterations on the transcriptional patterns in pancreatic cancer: implications for the interpretation of genomic amplifications

Molecular characterisation of patients with subtelomeric 22q abnormalities using chromosome specific array-based comparative genomic hybridisation

Molecular cytogenetic analysis of clustered sporadic and familial renal cell carcinoma-associated 3q13 approximately q22 breakpoints

Mutations in a new member of the chromodomain gene family cause CHARGE syndrome

Noonan syndrome, the SOS1 gene and embryonal rhabdomyosarcoma

Perivascular epithelioid cell tumor of gastrointestinal tract: case report and review of the literature

Predictors and risk model development for menopausal age in fragile X premutation carriers ⬇️

Prevalence of germline mutations in the spindle assembly checkpoint gene BUB1B in individuals with early-onset colorectal cancer

Rare pathogenic microdeletions and tandem duplications are microhomology-mediated and stimulated by local genomic architecture

Recurrent CNVs disrupt three candidate genes in schizophrenia patients

Regulation of the MiTF/TFE bHLH-LZ transcription factors through restricted spatial expression and alternative splicing of functional domains

Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study

Role of gain of 12p in germ cell tumour development

The (epi)genetics of human synovial sarcoma

The Mitotic Arrest Deficient Protein MAD2B Interacts with the Clathrin Light Chain A during Mitosis ⬇️

The Origin and Nature of Tightly Clustered BTG1 Deletions in Precursor B-Cell Acute Lymphoblastic Leukemia Support a Model of Multiclonal Evolution ⬇️

The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP

The epigenetics of (hereditary) colorectal cancer

The mitotic arrest deficient protein MAD2B interacts with the small GTPase RAN throughout the cell cycle

The renal cell carcinoma-associated oncogenic fusion protein PRCCTFE3 provokes p21 WAF1/CIP1-mediated cell cycle delay

Understanding familial and non-familial renal cell cancer

Unraveling genetic predisposition to familial or early onset gastric cancer using germline whole-exome sequencing

Upregulation of the transcription factor TFEB in t(6;11)(p21;q13)-positive renal cell carcinomas due to promoter substitution