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List of works by Alberto Podjarny

2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors

scientific article

A multicopy modeling of the water distribution in macromolecular crystals ⬇️

scientific article published on July 1, 1997

Aldose and aldehyde reductases: correlation of molecular modeling and mass spectrometric studies on the binding of inhibitors to the active site

scientific article published on 01 November 2000

Approaches to very low resolution phasing of the ribosome 50S particle from Thermus thermophilus by the few-atoms-models and molecular-replacement methods.

scientific article published in November 1996

Binding of aldose reductase inhibitors: correlation of crystallographic and mass spectrometric studies

scientific article published on 01 July 1999

Charge-density analysis of a protein structure at subatomic resolution: the human aldose reductase case.

scientific article

Class II aminoacyl transfer RNA synthetases: crystal structure of yeast aspartyl-tRNA synthetase complexed with tRNA(Asp)

scientific article

Comparison of hydrogen determination with X-ray and neutron crystallography in a human aldose reductase–inhibitor complex

scientific article published on 19 April 2006

Crystal packing modifies ligand binding affinity: The case of aldose reductase

scientific article

Crystal structure of a eukaryotic initiator tRNA ⬇️

scientific article published on March 8, 1979

Crystal structure of the nucleosome core particle at 16 A resolution.

scientific article published on June 1984

Crystallographic studies of protein denaturation and renaturation. 1. Effects of denaturants on volume and X-ray pattern of cross-linked triclinic lysozyme crystals

scientific article published on April 5, 1977

Crystallographic studies of protein denaturation and renaturation. 2. Sodium dodecyl sulfate induced structural changes in triclinic lysozyme

scientific article published on 01 April 1977

Density constraints and low-resolution phasing

scientific article published on 01 October 2000

Density modification in x-ray crystallography.

scientific article published on January 1996

Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications.

scientific article published in November 2004

Discovery of (R)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury ⬇️

scientific article published on March 8, 2013

Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications.

scientific article published in May 2005

Factorizing selectivity determinants of inhibitor binding toward aldose and aldehyde reductases: structural and thermodynamic properties of the aldose reductase mutant Leu300Pro-fidarestat complex.

scientific article published in September 2005

Frataxin from Psychromonas ingrahamii as a model to study stability modulation within the CyaY protein family

scientific article

Heavy-atom refinement against solvent-flattened phases.

scientific article published in September 1992

High resolution structure of the RNA duplex [U(U-A)6A]2.

scientific article published on September 1988

High-resolution crystal structure of AKR11C1 from Bacillus halodurans: an NADPH-dependent 4-hydroxy-2,3-trans-nonenal reductase.

scientific article published on 10 October 2005

High-resolution neutron and X-ray diffraction room-temperature studies of an H-FABP-oleic acid complex: study of the internal water cluster and ligand binding by a transferred multipolar electron-density distribution

scientific article

High-resolution neutron protein crystallography with radically small crystal volumes: application of perdeuteration to human aldose reductase.

scientific article

Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design

scientific article

Iminosugar-Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Levels

scientific article

Incorporation of methyl-protonated valine and leucine residues into deuterated ocean pout type III antifreeze protein: expression, crystallization and preliminary neutron diffraction studies.

scientific article

Linear and extended: a common polyglutamine conformation recognized by the three antibodies MW1, 1C2 and 3B5H10

scientific article

Low-resolution ab initio phasing: problems and advances.

scientific article published in October 2000

Low-resolution data analysis for low-density lipoprotein particle.

scientific article

Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features

scientific article

Metabolic regulation of the squid nerve Na(+)/Ca (2+) exchanger: recent developments.

scientific article published on January 2013

Modulation of aldose reductase inhibition by halogen bond tuning

scientific article

Neutron crystallography: opportunities, challenges, and limitations

scientific article published on 07 August 2008

Neutron structure of type-III antifreeze protein allows the reconstruction of AFP-ice interface

scientific article

New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM

scientific article

Novel NADPH-binding domain revealed by the crystal structure of aldose reductase ⬇️

scientific article published on January 30, 1992

On the ab initio solution of the phase problem for macromolecules at very low resolution: the few atoms model method.

scientific article published in November 1995

On the ab initio solution of the phase problem or macromolecules at very low resolution. II. Generalized likelihood based approach to cluster discrimination.

scientific article published in September 1998

On the solution of the molecular-replacement problem at very low resolution: application to large complexes.

scientific article published in November 1995

Perdeuteration, purification, crystallization and preliminary neutron diffraction of an ocean pout type III antifreeze protein.

scientific article published on 26 March 2009

Perdeuteration: improved visualization of solvent structure in neutron macromolecular crystallography

scientific article

Probing the roles of two tryptophans surrounding the unique zinc coordination site in lipase family I.5

scientific article

Probing the ultra-high resolution structure of aldose reductase with molecular modelling and noncovalent mass spectrometry.

scientific article

Production of crystals of human aldose reductase with very high resolution diffraction

scientific article published on 01 March 1999

Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase

scientific article

Selectivity determinants of the aldose and aldehyde reductase inhibitor-binding sites.

scientific article

Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10

scientific article

Structural analysis of denaturant-protein interactions: comparison between the effects of bromoethanol and SDS on denaturation and renaturation of triclinic lysozyme.

scientific article published in December 1977

Structural analysis of sulindac as an inhibitor of aldose reductase and AKR1B10

scientific article

Structural and functional studies of ReP1-NCXSQ, a protein regulating the squid nerve Na+/Ca2+ exchanger

scientific article

Structural characterization of metal binding to a cold-adapted frataxin

scientific article

Structural information content at high resolution: MAD versus native

scientific article published on 01 January 2003

Structural studies of pig lens aldose reductase: reversible dimerization of the enzyme

scientific article published on 01 January 1991

Structure determination of aldose reductase: joys and traps of local symmetry averaging

scientific article published on 01 March 1993

Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity.

scientific article published in August 2005

Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53.

scientific article

Subatomic and atomic crystallographic studies of aldose reductase: implications for inhibitor binding.

scientific article published on April 2004

Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase

scientific article published on 29 July 2015

Synthesis of quaternary α-amino acid-based arginase inhibitors via the Ugi reaction

scientific article

The Effect of Halogen-to-Hydrogen Bond Substitution on Human Aldose Reductase Inhibition

scientific article

The atomic resolution structure of human aldose reductase reveals that rearrangement of a bound ligand allows the opening of the safety-belt loop

scientific article

The crystallographic structure of the aldose reductase-IDD552 complex shows direct proton donation from tyrosine 48

scientific journal article

The role of the C-terminal region on the oligomeric state and enzymatic activity of Trypanosoma cruzi hypoxanthine phosphoribosyl transferase

scientific article

The structure of human aldose reductase bound to the inhibitor IDD384

scientific article

The structure of triclinic lysozyme at 2-5 A resolution

scientific article published in January 1976

Ultrahigh resolution drug design I: details of interactions in human aldose reductase-inhibitor complex at 0.66 A

scientific article

Ultrahigh-resolution study of protein atomic displacement parameters at cryotemperatures obtained with a helium cryostat

scientific article published on 23 November 2006

Unusual binding mode of the 2S4R stereoisomer of the potent aldose reductase cyclic imide inhibitor fidarestat (2S4S) in the 15 K crystal structure of the ternary complex refined at 0.78 A resolution: implications for the inhibition mechanism

scientific article

Validation of surface plasmon resonance screening of a diverse chemical library for the discovery of protein tyrosine phosphatase 1b binders ⬇️

scientific article published on September 29, 2011

Virtual screening for inhibitors of human aldose reductase.

scientific article

X-Ray Crystal Structure of the Full Length Human Chitotriosidase (CHIT1) Reveals Features of Its Chitin Binding Domain

scientific article

X-ray structure of the V301L aldo-keto reductase 1B10 complexed with NADP(+) and the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity

scientific article

X-ray-induced deterioration of disulfide bridges at atomic resolution

scientific article

X-ray-radiation-induced cooperative atomic movements in protein

scientific article

Yeast tRNA(Asp)-aspartyl-tRNA synthetase complex: low resolution crystal structure

scientific article published on 01 October 1987

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