List of works - Bogusław Nocek

A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair

scientific article

A family of metal-dependent phosphatases implicated in metabolite damage-control

scientific article

Activity screening of environmental metagenomic libraries reveals novel carboxylesterase families

scientific article

Assisted assignment of ligands corresponding to unknown electron density

scientific article

Biochemical and Structural Characterization of a Five-domain GH115 α-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T.

scientific article published on 18 April 2016

Biochemical and Structural Insights into Enzymatic Depolymerization of Polylactic Acid and Other Polyesters by Microbial Carboxylesterases.

scientific article

Bisphosphonic acids and related compounds as inhibitors of nucleotide- and polyphosphate-processing enzymes: A PPK1 and PPK2 case study.

scientific article

Cleavable C-terminal His-tag vectors for structure determination.

scientific article

Correction to differential stabilities and sequence-dependent base pair opening dynamics of watson-crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine

scientific article published on 10 April 2015

Crystallization and preliminary X-ray analysis of an R-2-hydroxypropyl-coenzyme M dehydrogenase

scientific article published on 23 August 2002

Crystallization and preliminary X-ray analysis of an acetone carboxylase from Xanthobacter autotrophicus strain Py2.

scientific article published on 23 January 2004

Determinants and Prediction of Esterase Substrate Promiscuity Patterns.

scientific article published on 28 November 2017

Differential stabilities and sequence-dependent base pair opening dynamics of Watson-Crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine

scientific article

Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila

scientific article

EPR and X-ray crystallographic characterization of the product-bound form of the MnII-loaded methionyl aminopeptidase from Pyrococcus furiosus

scientific article published in January 2005

Evolution of plant δ(1)-pyrroline-5-carboxylate reductases from phylogenetic and structural perspectives

scientific article published on 3 August 2015

Exploring Bacterial Carboxylate Reductases for the Reduction of Bifunctional Carboxylic Acids

scientific article published in August 2017

Functional Characterization of Four Putative δ1-Pyrroline-5-Carboxylate Reductases from Bacillus subtilis

scientific article published on 2 August 2017

Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS.

scientific article published on 12 June 2015

Functional and structural diversity in GH62 α-L-arabinofuranosidases from the thermophilic fungus Scytalidium thermophilum

scientific article published on 29 September 2014

Gene selection and cloning approaches for co-expression and production of recombinant protein-protein complexes.

scientific article published on 15 December 2015

Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril.

scientific article

Large-scale evaluation of protein reductive methylation for improving protein crystallization

scientific article published on October 2008

Mechanistic implications of the structure of the mixed-disulfide intermediate of the disulfide oxidoreductase, 2-ketopropyl-coenzyme M oxidoreductase/carboxylase

scientific article published in January 2006

Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.

scientific article

Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction.

scientific article

Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria

scientific article

Practical spectrophotometric assay for the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase, a potential antibiotic target

scientific article published on 26 April 2018

Resistance to Enediyne Antitumor Antibiotics by Sequestration

scientific article published on 21 June 2018

S-adenosyl-L-homocysteine hydrolase from a hyperthermophile (Thermotoga maritima) is expressed in Escherichia coli in inactive form - Biochemical and structural studies

scientific article published on 16 June 2017

Salvage of failed protein targets by reductive alkylation

scientific article

Screening and characterization of novel polyesterases from environmental metagenomes with high hydrolytic activity against synthetic polyesters

article

Structural Basis for Catalysis by the Mono- and Dimetalated Forms of the dapE-Encoded N-succinyl-l,l-Diaminopimelic Acid Desuccinylase

scientific article

Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation

scientific article

Structural Evidence for a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism.

scientific article published on 22 December 2017

Structural and Biochemical Characterization of AidC, a Quorum-Quenching Lactonase with Atypical Selectivity

scientific article

Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis

scientific article

Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases

scientific article published on 29 September 2015

Structural basis for CO2 fixation by a novel member of the disulfide oxidoreductase family of enzymes, 2-ketopropyl-coenzyme M oxidoreductase/carboxylase

scientific article

The CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis contains a [2Fe-2S] cluster: crystal structure and nuclease activity

scientific article

The Legionella pneumophila effector Ceg4 is a phosphotyrosine phosphatase that attenuates activation of eukaryotic MAPK pathways.

scientific article published on 4 January 2018

The activity of CouR, a MarR family transcriptional regulator, is modulated through a novel molecular mechanism

scientific article published on 22 September 2015

The dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase from Haemophilus influenzae contains two active-site histidine residues

scientific article published on 19 August 2008

The dimerization domain in DapE enzymes is required for catalysis

scientific article

The structure of Medicago truncatula δ(1)-pyrroline-5-carboxylate reductase provides new insights into regulation of proline biosynthesis in plants

scientific article

Toroidal Structure and DNA Cleavage by the CRISPR-Associated [4Fe-4S] Cluster Containing Cas4 Nuclease SSO0001 from Sulfolobus solfataricus

scientific article

List of works by Bogusław Nocek

A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair

A family of metal-dependent phosphatases implicated in metabolite damage-control

Activity screening of environmental metagenomic libraries reveals novel carboxylesterase families

Assisted assignment of ligands corresponding to unknown electron density

Biochemical and Structural Characterization of a Five-domain GH115 α-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T.

Biochemical and Structural Insights into Enzymatic Depolymerization of Polylactic Acid and Other Polyesters by Microbial Carboxylesterases.

Bisphosphonic acids and related compounds as inhibitors of nucleotide- and polyphosphate-processing enzymes: A PPK1 and PPK2 case study.

Cleavable C-terminal His-tag vectors for structure determination.

Correction to differential stabilities and sequence-dependent base pair opening dynamics of watson-crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine

Crystallization and preliminary X-ray analysis of an R-2-hydroxypropyl-coenzyme M dehydrogenase

Crystallization and preliminary X-ray analysis of an acetone carboxylase from Xanthobacter autotrophicus strain Py2.

Determinants and Prediction of Esterase Substrate Promiscuity Patterns.

Differential stabilities and sequence-dependent base pair opening dynamics of Watson-Crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine

Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila

EPR and X-ray crystallographic characterization of the product-bound form of the MnII-loaded methionyl aminopeptidase from Pyrococcus furiosus

Evolution of plant δ(1)-pyrroline-5-carboxylate reductases from phylogenetic and structural perspectives

Exploring Bacterial Carboxylate Reductases for the Reduction of Bifunctional Carboxylic Acids

Functional Characterization of Four Putative δ1-Pyrroline-5-Carboxylate Reductases from Bacillus subtilis

Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS.

Functional and structural diversity in GH62 α-L-arabinofuranosidases from the thermophilic fungus Scytalidium thermophilum

Gene selection and cloning approaches for co-expression and production of recombinant protein-protein complexes.

Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril.

Large-scale evaluation of protein reductive methylation for improving protein crystallization

Mechanistic implications of the structure of the mixed-disulfide intermediate of the disulfide oxidoreductase, 2-ketopropyl-coenzyme M oxidoreductase/carboxylase

Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.

Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction.

Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria

Practical spectrophotometric assay for the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase, a potential antibiotic target

Resistance to Enediyne Antitumor Antibiotics by Sequestration

S-adenosyl-L-homocysteine hydrolase from a hyperthermophile (Thermotoga maritima) is expressed in Escherichia coli in inactive form - Biochemical and structural studies

Salvage of failed protein targets by reductive alkylation

Screening and characterization of novel polyesterases from environmental metagenomes with high hydrolytic activity against synthetic polyesters

Structural Basis for Catalysis by the Mono- and Dimetalated Forms of the dapE-Encoded N-succinyl-l,l-Diaminopimelic Acid Desuccinylase

Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation

Structural Evidence for a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism.

Structural and Biochemical Characterization of AidC, a Quorum-Quenching Lactonase with Atypical Selectivity

Structural and Functional Characterization of Microcin C Resistance Peptidase MccF from Bacillus anthracis

Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases

Structural basis for CO2 fixation by a novel member of the disulfide oxidoreductase family of enzymes, 2-ketopropyl-coenzyme M oxidoreductase/carboxylase

The CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis contains a [2Fe-2S] cluster: crystal structure and nuclease activity

The Legionella pneumophila effector Ceg4 is a phosphotyrosine phosphatase that attenuates activation of eukaryotic MAPK pathways.

The activity of CouR, a MarR family transcriptional regulator, is modulated through a novel molecular mechanism

The dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase from Haemophilus influenzae contains two active-site histidine residues

The dimerization domain in DapE enzymes is required for catalysis

The structure of Medicago truncatula δ(1)-pyrroline-5-carboxylate reductase provides new insights into regulation of proline biosynthesis in plants

Toroidal Structure and DNA Cleavage by the CRISPR-Associated [4Fe-4S] Cluster Containing Cas4 Nuclease SSO0001 from Sulfolobus solfataricus