Search filters

List of works by Heinrich Sticht

11th German Conference on Chemoinformatics (GCC 2015) : Fulda, Germany. 8-10 November 2015.

scientific article (publication date: April 2016)

A Metadynamics-Based Protocol for the Determination of GPCR-Ligand Binding Modes

scientific article published on 22 April 2019

A Multiple Piccolino-RIBEYE Interaction Supports Plate-Shaped Synaptic Ribbons in Retinal Neurons

scientific article published on 29 January 2019

A common structural mechanism underlying GCMB mutations that cause hypoparathyroidism

A comparative study of HIV-1 and HTLV-I protease structure and dynamics reveals a conserved residue interaction network

scientific article published on 29 January 2011

A computational strategy for the prediction of functional linear peptide motifs in proteins

scientific article published on 31 October 2007

A dual phenotype of periventricular nodular heterotopia and frontometaphyseal dysplasia in one patient caused by a single FLNA mutation leading to two functionally different aberrant transcripts

scientific article

A modeling strategy for G-protein coupled receptors

article

A molecular model for the differential activation of STAT3 and STAT6 by the herpesviral oncoprotein tip.

scientific article

A mutation in the β-subunit of ENaC identified in a patient with cystic fibrosis-like symptoms has a gain-of-function effect

scientific article published on 19 October 2012

A mutation of the epithelial sodium channel associated with atypical cystic fibrosis increases channel open probability and reduces Na+ self inhibition

scientific article

A new redox-dependent mechanism of MMP-1 activity control comprising reduced low-molecular-weight thiols and oxidizing radicals.

scientific article published on 26 November 2008

A peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency

scientific article

A proline to glycine mutation in the Lck SH3-domain affects conformational sampling and increases ligand binding affinity

scientific article

A protein-specifically adapted scoring function for the reranking of docking solutions

scholarly article by Wolfgang Müller published in January 2007

A severe congenital myasthenic syndrome with "dropped head" caused by novel MUSK mutations.

scientific article published on 21 April 2015

A specific A/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interactions

scientific article

A tight lower bound on the mutual information of a binary and an arbitrary finite random variable as a function of the variational distance

A two-alpha-helix extra domain mediates the halophilic character of a plant-type ferredoxin from halophilic archaea

scientific article published in January 2005

AMBER force-field parameters for phosphorylated amino acids in different protonation states: phosphoserine, phosphothreonine, phosphotyrosine, and phosphohistidine

scientific article published on 21 October 2005

AMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability

scientific article

Agonist Binding and G Protein Coupling in Histamine H2 Receptor: A Molecular Dynamics Study

scientific article published on 12 September 2020

Alanine-glyoxylate aminotransferase 2 (AGXT2) polymorphisms have considerable impact on methylarginine and β-aminoisobutyrate metabolism in healthy volunteers

scientific article

Allergic cross-reactivity made visible: solution structure of the major cherry allergen Pru av 1

scientific article

Alpha-helix nucleation by a calcium-binding peptide loop

scientific article

Amino-Terminal Processing of Helicobacter pylori Serine Protease HtrA: Role in Oligomerization and Activity Regulation.

scientific article published on 16 April 2018

Amyloid-beta42 oligomer structures from fibrils: a systematic molecular dynamics study

scientific article published in February 2010

Amyloid-β dimers in the absence of plaque pathology impair learning and synaptic plasticity.

scientific article published on 10 December 2015

An information-theoretic classification of amino acids for the assessment of interfaces in protein-protein docking

scientific article published on 5 July 2013

An inhibitory peptide derived from the α-subunit of the epithelial sodium channel (ENaC) shows a helical conformation

scientific article published on 11 May 2012

Analysis of amino acid residues in the predicted transmembrane pore influencing transport kinetics of the hepatic drug transporter organic anion transporting polypeptide 1B1 (OATP1B1).

scientific article published in September 2016

Analysis of naturally occurring mutations in the human uptake transporter NaCT important for bone and brain development and energy metabolism.

scientific article published on 27 July 2018

Analysis of the structure-activity relationship of four herpesviral UL97 subfamily protein kinases reveals partial but not full functional conservation

scientific article published on November 2006

Antitermination in bacteriophage λ

scholarly article by Manuela Schärpf et al published April 2000 in FEBS Journal

Application of information theory to feature selection in protein docking

scientific article published on 12 July 2011

Autosomal-Recessive Mutations in the tRNA Splicing Endonuclease Subunit TSEN15 Cause Pontocerebellar Hypoplasia and Progressive Microcephaly

scientific article published on July 2016

Autosomal-Recessive Mutations in the tRNA Splicing Endonuclease Subunit TSEN15 Cause Pontocerebellar Hypoplasia and Progressive Microcephaly

scientific article published on September 2016

B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies

scientific article

Biallelic SEMA3A defects cause a novel type of syndromic short stature.

scientific article

Binding of histamine to the H1 receptor-a molecular dynamics study

scientific article published on 29 November 2018

Binding properties of SUMO-interacting motifs (SIMs) in yeast

Binding, domain orientation, and dynamics of the Lck SH3-SH2 domain pair and comparison with other Src-family kinases

scientific article

CD and NMR studies of prion protein (PrP) helix 1. Novel implications for its role in the PrPC-->PrPSc conversion process

scientific article published on 2 September 2003

CD83 and GRASP55 interact in human dendritic cells

scientific article published on 19 February 2015

CD83 is a dimer: Comparative analysis of monomeric and dimeric isoforms

scientific article

CTCF variants in 39 individuals with a variable neurodevelopmental disorder broaden the mutational and clinical spectrum

scientific article published on 26 June 2019

Casein kinase 2-dependent serine phosphorylation of MuSK regulates acetylcholine receptor aggregation at the neuromuscular junction

scientific article

Channel Estimation for Diffusive Molecular Communications

Channel estimation techniques for diffusion-based molecular communications

Characterization of Lck-binding elements in the herpesviral regulatory Tip protein

scientific article

Characterization of Recombinant Human Cytomegaloviruses Encoding IE1 Mutants L174P and 1-382 Reveals that Viral Targeting of PML Bodies Perturbs both Intrinsic and Innate Immune Responses

scientific article

Characterization of a discontinuous neutralizing epitope on glycoprotein B of human cytomegalovirus

scientific article published on 5 June 2013

Characterization of a single-chain variable fragment recognizing a linear epitope of aβ: a biotechnical tool for studies on Alzheimer's disease?

scientific article

Characterization of two mutations in the SPTLC1 subunit of serine palmitoyltransferase associated with hereditary sensory and autonomic neuropathy type I.

scientific article published on 24 February 2011

Characterizing the Interaction between the HTLV-1 Transactivator Tax-1 with Transcription Elongation Factor ELL2 and Its Impact on Viral Transactivation

scientific article published in 2021

Clinical relevance of systematic phenotyping and exome sequencing in patients with short stature.

scientific article published on 12 October 2017

Combining independent drug classes into superior, synergistically acting hybrid molecules.

scientific article published in November 2010

Confirmation of mutations in PROSC as a novel cause of vitamin B 6 -dependent epilepsy.

scientific article

Conformational Dynamics of Herpesviral NEC Proteins in Different Oligomerization States

scientific article published on 25 September 2018

Conformational stability of fibrillar amyloid-beta oligomers via protofilament pair formation - a systematic computational study

scientific article

Conformational switch upon phosphorylation: human CDK inhibitor p19INK4d between the native and partially folded state

scientific article

Crystal Structure of the Extracellular Domain of the Human Dendritic Cell Surface Marker CD83.

scientific article published on 14 March 2017

Crystal Structure of the Human Cytomegalovirus pUL50-pUL53 Core Nuclear Egress Complex Provides Insight into a Unique Assembly Scaffold for Virus-Host Protein Interactions

scientific article published on 2 October 2015

Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs

scientific article

Crystal structure of cytomegalovirus IE1 protein reveals targeting of TRIM family member PML via coiled-coil interactions

scientific article

Cytomegaloviral proteins that associate with the nuclear lamina: components of a postulated nuclear egress complex

scientific article

DAPK-HSF1 interaction as a positive-feedback mechanism stimulating TNF-induced apoptosis in colorectal cancer cells

scientific article

DNA binding by Corynebacterium glutamicum TetR-type transcription regulator AmtR

scientific article

DYNC2LI1 mutations broaden the clinical spectrum of dynein-2 defects

scientific journal article

De Novo Variants in MAPK8IP3 Cause Intellectual Disability with Variable Brain Anomalies

scientific article published on 03 January 2019

De Novo Variants in the F-Box Protein FBXO11 in 20 Individuals with a Variable Neurodevelopmental Disorder

scientific article published on 26 July 2018

De novo missense mutations in the NAA10 gene cause severe non-syndromic developmental delay in males and females

scientific article (publication date: May 2015)

De novo mutations in the genome organizer CTCF cause intellectual disability.

scientific article published on 06 June 2013

Diagnostic Yield and Novel Candidate Genes by Exome Sequencing in 152 Consanguineous Families With Neurodevelopmental Disorders.

scientific article published on 11 January 2017

Differential contribution of EF-hands to the Ca²⁺-dependent activation in the plant two-pore channel TPC1.

scientific article published on 18 August 2011

Disturbed Wnt Signalling due to a Mutation in CCDC88C Causes an Autosomal Recessive Non-Syndromic Hydrocephalus with Medial Diverticulum

scientific article

Dual selection pressure by drugs and HLA class I-restricted immune responses on human immunodeficiency virus type 1 protease

scientific article published on 3 January 2007

Dynamic regulatory interaction between cytomegalovirus major tegument protein pp65 and protein kinase pUL97 in intracellular compartments, dense bodies and virions.

scientific article published on 12 October 2017

Effect of HPr phosphorylation on structure, dynamics, and interactions in the course of transcriptional control

article

Effect of pathogenic mutations on the structure and dynamics of Alzheimer's A beta 42-amyloid oligomers.

scientific article

Effect of the SH3-SH2 domain linker sequence on the structure of Hck kinase

scientific article

Effects of histidine protonation and phosphorylation on histidine-containing phosphocarrier protein structure, dynamics, and physicochemical properties.

scientific article

Effects of the V82A and I54V mutations on the dynamics and ligand binding properties of HIV-1 protease

scientific article published on 27 February 2010

Elucidation of the phenotypic spectrum and genetic landscape in primary and secondary microcephaly

scientific article published on 07 March 2019

Equine infectious anemia virus Tat is a predominantly helical protein

scientific article published on December 1993

Equine infectious anemia virus transactivator is a homeodomain-type protein

scientific article published in April 1998

Erratum: Mimicking titration experiments with MD simulations: A protocol for the investigation of pH-dependent effects on proteins

scientific article

Erratum: Responsiveness of B cells is regulated by the hinge region of IgD

scientific article published on 01 July 2015

Estrogen and progesterone receptors: from molecular structures to clinical targets

scientific article (publication date: August 2009)

Evidence for genetic overlap between adult onset Still's disease and hereditary periodic fever syndromes

scientific article published on 20 November 2017

Evolutionary conserved networks of human height identify multiple Mendelian causes of short stature

scientific article published on 26 February 2019

Expanding the clinical and mutational spectrum of Kaufman oculocerebrofacial syndrome with biallelic UBE3B mutations

scientific article published on 11 March 2014

Expanding the clinical spectrum of COL1A1 mutations in different forms of glaucoma

scientific article published on 02 August 2016

Expression, purification, and structural analysis of intracellular C-termini from metabotropic glutamate receptors

scientific article published in January 2013

Functional analysis of chemically synthesized derivatives of the human CC chemokine CCL15/HCC-2, a high affinity CCR1 ligand

scientific article published on January 2004

Functional and Structural Relevance of Conserved Positively Charged Lysine Residues in Organic Anion Transporting Polypeptide 1B3

article

Functional null mutations in the gonosomal homologue gene TBL1Y are associated with non-syndromic coarctation of the aorta

scientific article published on February 2012

Further corroboration of distinct functional features in SCN2A variants causing intellectual disability or epileptic phenotypes

scientific article published on 27 February 2019

Further delineation of Pitt-Hopkins syndrome: phenotypic and genotypic description of 16 novel patients.

scientific article published on 26 August 2008

Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons

scientific article published on 30 December 2013

Genetic screening confirms heterozygous mutations in ACAN as a major cause of idiopathic short stature

scientific article published on 22 September 2017

Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine

scientific article published on 21 September 2014

Genotype-epigenotype-phenotype correlations in females with frontometaphyseal dysplasia

Genotype-phenotype evaluation of MED13L defects in the light of a novel truncating and a recurrent missense mutation.

scientific article

Group I metabotropic glutamate receptors bind to protein phosphatase 1C. Mapping and modeling of interacting sequences

scientific journal article

HIV-1 fusion is blocked through binding of GB Virus C E2-derived peptides to the HIV-1 gp41 disulfide loop [corrected]

scientific article

Haploinsufficiency of vascular endothelial growth factor related signaling genes is associated with tetralogy of Fallot

article

Heterozygous NTF4 mutations impairing neurotrophin-4 signaling in patients with primary open-angle glaucoma

scientific article

Heterozygous and homozygous variants in STX1A cause a neurodevelopmental disorder with or without epilepsy

scientific article published in 2022

Human TBX1 missense mutations cause gain of function resulting in the same phenotype as 22q11.2 deletions

scientific article

Hybrid compounds: from simple combinations to nanomachines

scientific article

Hypomorphic Pathogenic Variants in TAF13 Are Associated with Autosomal-Recessive Intellectual Disability and Microcephaly

scientific article published on March 2017

IFN-γ-response mediator GBP-1 represses human cell proliferation by inhibiting the Hippo signaling transcription factor TEAD

scientific article published on 25 September 2018

Identification and characterization of a eukaryotically encoded rubredoxin in a cryptomonad alga.

scientific article published on April 2000

Identification of a Ninein (NIN) mutation in a family with spondyloepimetaphyseal dysplasia with joint laxity (leptodactylic type)-like phenotype

scientific article published on 9 May 2013

Identification of a neutralizing epitope within antigenic domain 5 of glycoprotein B of human cytomegalovirus

scientific article

Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6)

scientific journal article

Identification of mutations in DYNC2LI1, a member of the mammalian cytoplasmic dynein 2 complex, expands the clinical spectrum of Jeune/ATD ciliopathies.

scientific article published on 13 July 2015

Identification of the structural features that mediate binding specificity in the recognition of STAT proteins by dual-specificity phosphatases

scientific article published on 01 January 2012

Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models

article

Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models

scientific article

Impact of the C-terminal disulfide bond on the folding and stability of onconase

scientific article

Improving the efficiency of the Gaussian conformational database potential for the refinement of protein and nucleic acid structures

scientific article published in December 2001

In Silico Study of Camptothecin-Based Pro-Drugs Binding to Human Carboxylesterase 2

scientific article published in 2024

IndependentNF1andPTPN11mutations in a family with neurofibromatosis-Noonan syndrome

Infantile Epileptic Encephalopathy, Transient Choreoathetotic Movements, and Hypersomnia due to a De Novo Missense Mutation in the SCN2A Gene

article

Inhibition of RAS activation due to a homozygous ezrin variant in patients with profound intellectual disability.

scientific article published on February 2015

Insight into the phosphoryl transfer of the Escherichia coli glucose phosphotransferase system from QM/MM simulations.

scientific article published on 25 September 2008

Insights into amprenavir resistance in E35D HIV-1 protease mutation from molecular dynamics and binding free-energy calculations.

scientific article published on 23 June 2006

Interaction of Glycolipids with the Macrophage Surface Receptor Mincle - a Systematic Molecular Dynamics Study.

scientific article published on 29 March 2018

Investigation of the dynamics of the viral immediate-early protein 1 in different conformations and oligomerization states

scientific article published on 24 June 2015

Loss of function of SVBP leads to autosomal recessive intellectual disability, microcephaly, ataxia, and hypotonia

scientific article published on 04 January 2019

MAP4-dependent regulation of microtubule formation affects centrosome, cilia, and Golgi architecture as a central mechanism in growth regulation.

scientific article published on 28 November 2014

Mimicking titration experiments with MD simulations: A protocol for the investigation of pH-dependent effects on proteins

scientific article

Missense Variants in RHOBTB2 Cause a Developmental and Epileptic Encephalopathy in Humans, and Altered Levels Cause Neurological Defects in Drosophila.

scientific article published on 13 December 2017

Modulation of Recombinant Human α1 Glycine Receptors by Mono- and Disaccharides: A Kinetic Study

scientific article published on 26 May 2016

Molecular Dynamics Simulation of Equine Infectious Anemia Virus Tat Protein in Water and in 40% Trifluoroethanol

scientific article

Molecular Dynamics Simulations of HIV-1 Protease Suggest Different Mechanisms Contributing to Drug Resistance.

scientific article

Molecular mechanism of HIV-1 gp120 mutations that reduce CD4 binding affinity

article

Molecular modeling of the interleukin-19 receptor complex. Novel aspects of receptor recognition in the interleukin-10 cytokine family

scientific article published on 9 July 2004

Motif-Mediated Protein Interactions and their Role in Disease

Mouse ApoM displays an unprecedented seven-stranded lipocalin fold: folding decoy or alternative native fold?

scientific article

Mutations in CYP1B1 cause primary congenital glaucoma by reduction of either activity or abundance of the enzyme.

scientific article published in September 2008

Mutations in DCPS and EDC3 in autosomal recessive intellectual disability indicate a crucial role for mRNA decapping in neurodevelopment

scientific article

Mutations in IL36RN in patients with generalized pustular psoriasis

scientific article published on 6 May 2013

Mutations in MEF2C from the 5q14.3q15 microdeletion syndrome region are a frequent cause of severe mental retardation and diminish MECP2 and CDKL5 expression

scientific article published in June 2010

Mutations in STRA6 cause a broad spectrum of malformations including anophthalmia, congenital heart defects, diaphragmatic hernia, alveolar capillary dysplasia, lung hypoplasia, and mental retardation

scientific article

Mutations in herpes simplex virus gD protein affect receptor binding by different molecular mechanisms

scientific article published on 20 March 2014

N(8)-acetylspermidine as a potential plasma biomarker for Snyder-Robinson syndrome identified by clinical metabolomics

scientific article

NDST1 missense mutations in autosomal recessive intellectual disability

scientific article published on 14 August 2014

Noncanonical NF-κB activation by the oncoprotein Tio occurs through a nonconserved TRAF3-binding motif

scientific article published on 23 April 2013

Novel mode of phosphorylation-triggered reorganization of the nuclear lamina during nuclear egress of human cytomegalovirus

scientific article

Nuclear Egress Complexes of HCMV and Other Herpesviruses: Solving the Puzzle of Sequence Coevolution, Conserved Structures and Subfamily-Spanning Binding Properties

scientific article published on 24 June 2020

Nuclear import of isoforms of the cytomegalovirus kinase pUL97 is mediated by differential activity of NLS1 and NLS2 both acting through classical importin-α binding.

scientific article published on 2 May 2012

Null mutation in PGAP1 impairing Gpi-anchor maturation in patients with intellectual disability and encephalopathy

scientific article

Oral treatment with the d-enantiomeric peptide D3 improves the pathology and behavior of Alzheimer's Disease transgenic mice

scientific article

Overexpression, Purification, and Biochemical Characterization of the Extracellular Human CD83 Domain and Generation of Monoclonal Antibodies

scientific article published in April 2002

Oxidative stress-induced posttranslational modifications of human hemoglobin in erythrocytes

scientific article

PNUTS forms a trimeric protein complex with GABA(C) receptors and protein phosphatase 1.

scientific article

Palmoplantar Pustular Psoriasis Is Associated with Missense Variants in CARD14, but Not with Loss-of-Function Mutations in IL36RN in European Patients

scientific article published on 19 May 2015

Peptides presenting the binding site of human CD4 for the HIV-1 envelope glycoprotein gp120.

scientific article published on 31 October 2012

Phenotypic Variability in a Large Czech Family with a Dynamin 2–Associated Charcot-Marie-Tooth Neuropathy

article

Premature osteoarthritis as presenting sign of type II collagenopathy: a case report and literature review

scientific article published on 19 June 2012

Probing the Structure of the Escherichia coli Periplasmic Proteins HdeA and YmgD by Molecular Dynamics Simulations.

scientific article published on 27 October 2016

Probing the potential of CnaB-type domains for the design of tag/catcher systems.

scientific article published on 27 June 2017

Probing the role of intercalating protein sidechains for kink formation in DNA.

scientific article published on 12 February 2018

Profiling of WDR36 missense variants in German patients with glaucoma

scientific article published on January 2008

Protective capacity of neutralizing and non-neutralizing antibodies against glycoprotein B of cytomegalovirus.

scientific article published on 30 August 2017

Proteomic Interaction Patterns between Human Cyclins, the Cyclin-Dependent Kinase Ortholog pUL97 and Additional Cytomegalovirus Proteins

scientific article published on 18 August 2016

Proteomic analysis of the multimeric nuclear egress complex of human cytomegalovirus

scientific article published on 26 June 2014

Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study

scientific article

Rare Loss-of-Function Mutation in SERPINA3 in Generalized Pustular Psoriasis

scientific article published on 13 January 2020

Rational Design of β-Sheet Ligands Against Aβ42-Induced Toxicity

article

Recognition of T-rich single-stranded DNA by the cold shock protein Bs-CspB in solution

scientific article published on 06 September 2006

Relevance of conserved lysine and arginine residues in transmembrane helices for the transport activity of organic anion transporting polypeptide 1B3.

scientific article

Responsiveness of B cells is regulated by the hinge region of IgD.

scientific article

Role of the N-terminus for the stability of an amyloid-β fibril with three-fold symmetry

scientific article published on 12 October 2017

SPATA5 mutations cause a distinct autosomal recessive phenotype of intellectual disability, hypotonia and hearing loss

scientific article (publication date: 29 September 2016)

SUMO E3 ligases are expressed in the retina and regulate SUMOylation of the metabotropic glutamate receptor 8b.

scientific article

Secondary structure and tertiary fold of the birch pollen allergen Bet v 1 in solution.

scientific article

Selection and Characterization of Tau Binding ᴅ-Enantiomeric Peptides with Potential for Therapy of Alzheimer Disease

scientific article

Sequence-specific 1H, 13C and 15N resonance assignments and secondary structure of [2Fe-2S] ferredoxin from Halobacterium salinarum

article

Sequence-specific 1H, 13C and 15N resonance assignments of the SH3-SH2 domain pair from the human tyrosine kinase Lck.

scientific article published in December 2003

Sequence-specific 1H, 13C and 15N resonance assignments of the major cherry allergen Pru a 1

scientific article published on 01 September 2000

Severely incapacitating mutations in patients with extreme short stature identify RNA-processing endoribonuclease RMRP as an essential cell growth regulator

scientific article

Single expressed glycine receptor domains reconstitute functional ion channels without subunit-specific desensitization behavior

scientific article published on 20 August 2014

Small ubiquitin-related modifier (SUMO) pathway-mediated enhancement of human cytomegalovirus replication correlates with a recruitment of SUMO-1/3 proteins to viral replication compartments

scientific article published on 13 February 2013

Solution structure of cytochrome c6 from the thermophilic cyanobacterium Synechococcus elongatus.

scientific article published in January 1998

Solution structure of the glycosylated second type 2 module of fibronectin

scientific article

Solution structure of the human CC chemokine 2: A monomeric representative of the CC chemokine subtype

scientific article

Spatially clustering de novo variants in CYFIP2, encoding the cytoplasmic FMRP interacting protein 2, cause intellectual disability and seizures

scientific article published on 21 January 2019

Specific residues of a conserved domain in the N terminus of the human cytomegalovirus pUL50 protein determine its intranuclear interaction with pUL53.

scientific article published on 15 May 2012

Structural Basis for Species Selectivity in the HIV-1 gp120-CD4 Interaction: Restoring Affinity to gp120 in Murine CD4 Mimetic Peptides

scientific article

Structural analysis of the protein phosphatase 1 docking motif: molecular description of binding specificities identifies interacting proteins

scientific article published in January 2006

Structural and functional dissection reveals distinct roles of Ca2+-binding sites in the giant adhesin SiiE of Salmonella enterica

scientific article

Structural basis for the recognition of human cytomegalovirus glycoprotein B by a neutralizing human antibody

scientific article

Structural characterization of Lyn-SH3 domain in complex with a herpesviral protein reveals an extended recognition motif that enhances binding affinity

scientific article

Structural characterization of intracellular C-terminal domains of group III metabotropic glutamate receptors

scientific article

Structural insight into the giant Ca²⁺-binding adhesin SiiE: implications for the adhesion of Salmonella enterica to polarized epithelial cells

scientific article

Structural investigation of the binding of a herpesviral protein to the SH3 domain of tyrosine kinase Lck

scientific article

Structural rearrangements of HIV-1 Tat-responsive RNA upon binding of neomycin B

scientific article

Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity

scientific article

Structure of Synechococcus elongatus [Fe2S2] ferredoxin in solution

scientific article

Structure of amyloid A4-(1-40)-peptide of Alzheimer's disease

scientific article

Structure of human parathyroid hormone 1-37 in solution

scientific article

Structure-based functional analysis of effector protein SifA in living cells reveals motifs important for Salmonella intracellular proliferation

scientific article

Synthesis and characterization of the human CC chemokineHCC-2

scientific article published on 01 December 1999

Synthetic Peptides as Protein Mimics

scientific article

Synthetic Protein Scaffolds Based on Peptide Motifs and Cognate Adaptor Domains for Improving Metabolic Productivity

scientific article

Systematic analysis of phosphotyrosine antibodies recognizing single phosphorylated EPIYA-motifs in CagA of East Asian-type Helicobacter pylori strains

scientific article

Systematic analysis of phosphotyrosine antibodies recognizing single phosphorylated EPIYA-motifs in CagA of Western-type Helicobacter pylori strains

scientific article

The C-terminal coiled-coil domain of Corynebacterium diphtheriae DIP0733 is crucial for interaction with epithelial cells and pathogenicity in invertebrate animal model systems

scientific article published on 04 September 2018

The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain

scientific article published on 11 August 2015

The Oligomeric Assemblies of Cytomegalovirus Core Nuclear Egress Proteins Are Associated with Host Kinases and Show Sensitivity to Antiviral Kinase Inhibitors

scientific article published on 11 May 2022

The Prolyl Isomerase Pin1 Promotes the Herpesvirus-Induced Phosphorylation-Dependent Disassembly of the Nuclear Lamina Required for Nucleocytoplasmic Egress

scientific article

The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor 2 chains

scientific article

The chemical class of quinazoline compounds provides a core structure for the design of anticytomegaloviral kinase inhibitors

scientific article published on 8 August 2016

The clinical significance of small copy number variants in neurodevelopmental disorders

scientific article

The conformational stability of nonfibrillar amyloid-β peptide oligomers critically depends on the C-terminal peptide length

scientific article published on 11 February 2014

The cyclin-dependent kinase ortholog pUL97 of human cytomegalovirus interacts with cyclins

scientific article published on 18 December 2013

The cytomegalovirus egress proteins pUL50 and pUL53 are translocated to the nuclear envelope through two distinct modes of nuclear import

scientific article

The degenerin region of the human bile acid-sensitive ion channel (BASIC) is involved in channel inhibition by calcium and activation by bile acids.

scientific article published on 27 March 2018

The genetic basis for most patients with pustular skin disease remains elusive

scientific article published on 5 August 2017

The human cytomegalovirus nuclear egress complex unites multiple functions: Recruitment of effectors, nuclear envelope rearrangement, and docking to nuclear capsids

scientific article

The interleukin-10 family of cytokines

scientific article (publication date: February 2002)

The pH-dependent Client Release from the Collagen-specific Chaperone HSP47 Is Triggered by a Tandem Histidine Pair

scientific article published on 19 April 2016

The polynucleotide kinase 3′-phosphatase gene (PNKP) is involved in Charcot-Marie-Tooth disease (CMT2B2) previously related to MED25

article

The role of recessive inheritance in early-onset epileptic encephalopathies: a combined whole-exome sequencing and copy number study

scientific article published on 14 December 2018

The structure of iron-sulfur proteins

scientific article published in January 1998

The structure of the coliphage HK022 Nun protein-lambda-phage boxB RNA complex. Implications for the mechanism of transcription termination

scientific article

The transcription regulator RbsR represents a novel interaction partner of the phosphoprotein HPr-Ser46-P in Bacillus subtilis

scientific article

Thymosin β4 and tissue transglutaminase. Molecular characterization of cyclic thymosin β4.

scientific article published in August 2013

Transfer of HTLV-1 p8 and Gag to target T-cells depends on VASP, a novel interaction partner of p8

scientific article published on 30 September 2020

Trifluoroethanol stabilizes a helix-turn-helix motif in equine infectious-anemia-virus trans-activator protein

scientific article

Two isoforms of the protein kinase pUL97 of human cytomegalovirus are differentially regulated in their nuclear translocation

scientific article

Two novel mutations in the insulin binding subunit of the insulin receptor gene without insulin binding impairment in a patient with Rabson-Mendenhall syndrome

scientific article

Validation of the reliability of computational O-GlcNAc prediction

scientific article published on 9 December 2013

Variants in ASB10 are associated with open-angle glaucoma

scientific article

Variants in CPLX1 in two families with autosomal-recessive severe infantile myoclonic epilepsy and ID.

scientific article published on 19 April 2017

Whole exome sequencing reveals a novel de novo FOXC1 mutation in a patient with unrecognized Axenfeld-Rieger syndrome and glaucoma

scientific article published on 9 May 2015

enters gut epithelial cells and impairs intestinal barrier function through cleavage of occludin by serine protease HtrA

scientific article published on 13 February 2019

pH-dependent molecular dynamics of vesicular stomatitis virus glycoprotein G.

scientific article published on 10 August 2012