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List of works by Karl Mechtler

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Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

scientific article (publication date: March 2001)
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

scientific article (publication date: 2 November 2001)
Partitioning and plasticity of repressive histone methylation states in mammalian chromatin

scientific article (publication date: December 2003)
Systematic analysis of human protein complexes identifies chromosome segregation proteins

scientific article
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase

scientific article published in February 2007
Universal and confident phosphorylation site localization using phosphoRS.

scientific article published on 10 November 2011
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals

scientific article
Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2.

scientific article
Wapl controls the dynamic association of cohesin with chromatin

scientific article
Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.

scientific article
Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells

scientific article
The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.

scientific article published on 9 March 2003
Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells.

scientific article published in March 2006
Phosphorylation of the cohesin subunit Scc1 by Polo/Cdc5 kinase regulates sister chromatid separation in yeast

scientific article
Mitotic regulation of the human anaphase-promoting complex by phosphorylation

scientific article
Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells

scientific journal article
Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing

scientific article
Sororin mediates sister chromatid cohesion by antagonizing Wapl

scientific article
Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity.

scientific article published in March 2009
Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes

scientific article published on July 1992
ATP hydrolysis is required for cohesin's association with chromosomes

scientific article published in November 2003
Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion

scientific article
An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila

scientific article
Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis

scientific article published on 19 September 2005
Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex

scientific article
Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage

scientific article
HSPC117 is the essential subunit of a human tRNA splicing ligase complex

scientific article
MS Amanda, a universal identification algorithm optimized for high accuracy tandem mass spectra

scientific article published on 26 June 2014
Monopolar attachment of sister kinetochores at meiosis I requires casein kinase 1.

scientific article
Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase

scientific article
CENP-T proteins are conserved centromere receptors of the Ndc80 complex

scientific article
Charting the molecular network of the drug target Bcr-Abl

scientific article
A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors

scientific article published on 23 August 2011
Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling

scientific article
14-3-3 proteins recognize a histone code at histone H3 and are required for transcriptional activation

scientific article published on 6 December 2007
Topology and organization of the Salmonella typhimurium type III secretion needle complex components

scientific article published in April 2010
Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes

scientific article published on March 2007
APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex.

scientific article published on 24 September 2012
A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila

scientific article
Phosphoregulation of the budding yeast EB1 homologue Bim1p by Aurora/Ipl1p

scientific article published on August 2009
Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin

scientific article published on 30 July 2013
Peptide labeling with isobaric tags yields higher identification rates using iTRAQ 4-plex compared to TMT 6-plex and iTRAQ 8-plex on LTQ Orbitrap

scientific article published on August 2010
McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR

scientific article
High Precision Quantitative Proteomics Using iTRAQ on an LTQ Orbitrap: A New Mass Spectrometric Method Combining the Benefits of All

scientific article
A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors

scientific article
Unambiguous phosphosite localization using electron-transfer/higher-energy collision dissociation (EThcD)

scientific article
Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins

scholarly article
Inter-homolog crossing-over and synapsis in Arabidopsis meiosis are dependent on the chromosome axis protein AtASY3

scientific article
Quantitative phosphoproteomics of the ataxia telangiectasia-mutated (ATM) and ataxia telangiectasia-mutated and rad3-related (ATR) dependent DNA damage response in Arabidopsis thaliana

scientific article
Polysialylation controls dendritic cell trafficking by regulating chemokine recognition

scientific article published on 10 December 2015

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