List of works - Saskia Middeldorp

A novel mutation in the F5 gene (factor V Amsterdam) associated with bleeding independent of factor V procoagulant function.

scientific article published on 29 January 2015

ALIFE2 study: low-molecular-weight heparin for women with recurrent miscarriage and inherited thrombophilia--study protocol for a randomized controlled trial

scientific article

AQUILA: assessment of quality in lower limb arthroplasty. An expert Delphi consensus for total knee and total hip arthroplasty

scientific article

An anticoagulant that does not cause bleeding - an abrupt stop on the road to the Holy Grail

scientific article published on 01 December 2019

Anticoagulant interventions in hospitalized patients with COVID-19: A scoping review of randomized controlled trials and call for international collaboration

scientific article published on 05 September 2020

Anticoagulants for the prevention and treatment of catheter-related thrombosis in adults and children on parenteral nutrition: a systematic review and critical appraisal

scientific article

Antiplatelet drugs for polycythaemia vera and essential thrombocythaemia

scientific article

Antiplatelet drugs for polycythaemia vera and essential thrombocythaemia

scientific article (published 2008-04-23)

Antithrombotic therapy for pregnancy loss

scientific article

Aspirin and/or heparin for women with unexplained recurrent miscarriage with or without inherited thrombophilia

scientific article

Aspirin or anticoagulants for treating recurrent miscarriage in women without antiphospholipid syndrome

scientific article

Aspirin plus heparin or aspirin alone in women with recurrent miscarriage

scientific article

Benefits and harms of 4-factor prothrombin complex concentrate for reversal of vitamin K antagonist associated bleeding: a systematic review and meta-analysis

scientific article

Clinical Course of Cerebral Venous Thrombosis in Adult Acute Lymphoblastic Leukemia

scientific article published on 29 April 2015

Clinical implications of incidental venous thromboembolism in cancer patients

scientific article published on 06 February 2020

Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular disease

scientific article (publication date: 19 January 2011)

Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular disease

scientific article

Definition of bleeding events in studies evaluating prophylactic antithrombotic therapy in pregnant women: A systematic review and a proposal from the ISTH SSC

scientific article published on 12 August 2019

Development and implementation of common data elements for venous thromboembolism research: on behalf of SSC Subcommittee on official Communication from the SSC of the ISTH

scientific article published on 01 January 2021

Differences in thrombin and plasmin generation potential between East African and Western European adults: The role of genetic and non‐genetic factors

scientific article published in 2022

Different risk of deep vein thrombosis and pulmonary embolism in carriers with factor V Leiden compared with non-carriers, but not in other thrombophilic defects. Results from a large retrospective family cohort study

scientific article

Direct thrombin inhibitors

scientific article

Does thrombophilia testing help in the clinical management of patients?

scientific article

Duration of anticoagulant therapy for venous thromboembolism: balancing benefits and harms on the long term

scientific article

Duration of treatment with vitamin K antagonists in symptomatic venous thromboembolism

scientific article

Early migration of tibial components is associated with late revision: a systematic review and meta-analysis of 21,000 knee arthroplasties

scientific article published on 9 November 2012

Early proximal migration of cups is associated with late revision in THA: a systematic review and meta-analysis of 26 RSA studies and 49 survivalstudies

scientific article published on 5 November 2012

Early subsidence of shape-closed hip arthroplasty stems is associated with late revision. A systematic review and meta-analysis of 24 RSA studies and 56 survival studies

scientific article

Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism

scientific article

Effects of cancer on platelets

scientific article published on 24 April 2014

Emergencies on direct oral anticoagulants: Management, outcomes, and laboratory effects of prothrombin complex concentrate

scientific article published on 23 April 2020

Endogenous sex hormones and risk of venous thromboembolism in young women

scientific article published on 04 June 2019

Evidence-based approach to thrombophilia testing

scientific article

Guidance for the treatment and prevention of obstetric-associated venous thromboembolism

scientific article

Heart rate variability and first cardiovascular event in populations without known cardiovascular disease: meta-analysis and dose-response meta-regression

scientific article

Imaging for the exclusion of pulmonary embolism in pregnancy

scientific article

Imaging for the exclusion of pulmonary embolism in pregnancy.

scientific article

Incidence of postpartum haemorrhage in women receiving therapeutic doses of low-molecular-weight heparin: results of a retrospective cohort study

scientific article published on 14 November 2011

Incidence of venous thromboembolism in hospitalized patients with COVID-19

scientific article published on 05 May 2020

Inherited thrombophilia and pregnancy complications revisited.

scientific article

Inherited thrombophilias

scientific article published on September 2006

Introduction to the analysis of next generation sequencing data and its application to venous thromboembolism.

scientific article

Is Thrombophilia Testing Useful? ⬇️

scientific article published on January 1, 2011

Low-molecular-weight heparin and recurrent placenta-mediated pregnancy complications: a meta-analysis of individual patient data from randomised controlled trials.

scientific article published on 6 October 2016

Low-molecular-weight heparin for prevention of placenta-mediated pregnancy complications: protocol for a systematic review and individual patient data meta-analysis (AFFIRM).

scientific article

Mechanistic View of Risk Factors for Venous Thromboembolism ⬇️

scientific article published on March 1, 2012

Nasal Levels of Antimicrobial Peptides in Allergic Asthma Patients and Healthy Controls: Differences and Effect of a Short 1,25(OH)2 Vitamin D3 Treatment

scientific article published on 6 November 2015

Oral contraceptives and the risk of venous thromboembolism

scientific article

Parenteral anticoagulation for prolonging survival in patients with cancer who have no other indication for anticoagulation

scientific article

Parenteral anticoagulation in ambulatory patients with cancer

scientific article

Parenteral anticoagulation in patients with cancer who have no therapeutic or prophylactic indication for anticoagulation

scientific article (published 2011-01-19)

Parenteral anticoagulation in patients with cancer who have no therapeutic or prophylactic indication for anticoagulation

scientific article

Parenteral anticoagulation may prolong the survival of patients with limited small cell lung cancer: a Cochrane systematic review

scientific article published on 15 May 2008

Pregnancy failure and heritable thrombophilia

scientific article (publication date: April 2007)

Prognostic characteristics and body mass index in patients with pulmonary embolism: does size matter?

scientific article published on 10 January 2020

Prophylaxis for venous thromboembolism during asparaginase therapy in patients treated for acute lymphoblastic leukemia

scientific article

Prophylaxis for venous thromboembolism during asparaginase therapy in patients treated for acute lymphoblastic leukemia

scientific article (publication date: 31 May 2016)

Pulmonary embolism at autopsy in cancer patients

scientific article published on 26 March 2021

RSA prediction of high failure rate for the uncoated Interax TKA confirmed by meta-analysis

scientific article published in April 2012

Relevance of the JAK2V617F mutation in patients with deep vein thrombosis of the leg ⬇️

scientific article published on April 12, 2011

Reproducibility of exhaled nitric oxide measurements in overweight and obese adults

scientific article

Risk Factors for Cerebral Venous Thrombosis.

scientific article

Sex matters: Practice 5P's when treating young women with venous thromboembolism

scientific article published on 23 July 2019

Sex-specific differences in the distal versus proximal presenting location of acute deep vein thrombosis

scientific article published on 26 October 2018

The Netherlands Epidemiology of Obesity (NEO) study: study design and data collection

scientific article

The absolute risk of venous thrombosis after air travel: a cohort study of 8,755 employees of international organisations

scientific article published in September 2007

The prothrombin time does not predict the risk of recurrent venous thromboembolism or major bleeding in rivaroxaban-treated patients

scientific article published on 15 August 2018

The risk of venous thrombosis after air travel: contribution of clinical risk factors

scientific article

Thrombophilia and new anticoagulant drugs

scientific article

Thrombophilia testing for prevention of recurrent venous thromboembolism

scientific article (publication date: 12 December 2012)

Thrombophilia testing for prevention of recurrent venous thromboembolism

scientific article (published 2009-01-21)

Thrombophilia testing for prevention of recurrent venous thromboembolism

scientific article

Thromboprophylaxis in pregnant women: For whom and which LMWH dosage?

scientific article published on 01 August 2019

Thrombosis and hemostasis health in pregnancy: Registries from the International Society on Thrombosis and Haemostasis

scientific article published on 01 August 2019

Transgender patients and the role of the coagulation clinician

scientific article published on 13 September 2019

Treatment for superficial thrombophlebitis of the leg

scientific article

Treatment for superficial thrombophlebitis of the leg

scientific article (publication date: 14 March 2012)

Treatment for superficial thrombophlebitis of the leg

scientific article (published 2007-04-18)

Treatment of lower extremity superficial thrombophlebitis

scientific article

Treatment of superficial vein thrombosis to prevent deep vein thrombosis and pulmonary embolism: a systematic review.

scientific article

TropicALL study: Thromboprophylaxis in Children treated for Acute Lymphoblastic Leukemia with Low-molecular-weight heparin: a multicenter randomized controlled trial

scientific article

VTE, thrombophilia, antithrombotic therapy, and pregnancy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

scientific article

List of works by Saskia Middeldorp

A novel mutation in the F5 gene (factor V Amsterdam) associated with bleeding independent of factor V procoagulant function.

ALIFE2 study: low-molecular-weight heparin for women with recurrent miscarriage and inherited thrombophilia--study protocol for a randomized controlled trial

AQUILA: assessment of quality in lower limb arthroplasty. An expert Delphi consensus for total knee and total hip arthroplasty

An anticoagulant that does not cause bleeding - an abrupt stop on the road to the Holy Grail

Anticoagulant interventions in hospitalized patients with COVID-19: A scoping review of randomized controlled trials and call for international collaboration

Anticoagulants for the prevention and treatment of catheter-related thrombosis in adults and children on parenteral nutrition: a systematic review and critical appraisal

Antiplatelet drugs for polycythaemia vera and essential thrombocythaemia

Antiplatelet drugs for polycythaemia vera and essential thrombocythaemia

Antithrombotic therapy for pregnancy loss

Aspirin and/or heparin for women with unexplained recurrent miscarriage with or without inherited thrombophilia

Aspirin or anticoagulants for treating recurrent miscarriage in women without antiphospholipid syndrome

Aspirin plus heparin or aspirin alone in women with recurrent miscarriage

Benefits and harms of 4-factor prothrombin complex concentrate for reversal of vitamin K antagonist associated bleeding: a systematic review and meta-analysis

Clinical Course of Cerebral Venous Thrombosis in Adult Acute Lymphoblastic Leukemia

Clinical implications of incidental venous thromboembolism in cancer patients

Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular disease

Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular disease

Definition of bleeding events in studies evaluating prophylactic antithrombotic therapy in pregnant women: A systematic review and a proposal from the ISTH SSC

Development and implementation of common data elements for venous thromboembolism research: on behalf of SSC Subcommittee on official Communication from the SSC of the ISTH

Differences in thrombin and plasmin generation potential between East African and Western European adults: The role of genetic and non‐genetic factors

Different risk of deep vein thrombosis and pulmonary embolism in carriers with factor V Leiden compared with non-carriers, but not in other thrombophilic defects. Results from a large retrospective family cohort study

Direct thrombin inhibitors

Does thrombophilia testing help in the clinical management of patients?

Duration of anticoagulant therapy for venous thromboembolism: balancing benefits and harms on the long term

Duration of treatment with vitamin K antagonists in symptomatic venous thromboembolism

Early migration of tibial components is associated with late revision: a systematic review and meta-analysis of 21,000 knee arthroplasties

Early proximal migration of cups is associated with late revision in THA: a systematic review and meta-analysis of 26 RSA studies and 49 survivalstudies

Early subsidence of shape-closed hip arthroplasty stems is associated with late revision. A systematic review and meta-analysis of 24 RSA studies and 56 survival studies

Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism

Effects of cancer on platelets

Emergencies on direct oral anticoagulants: Management, outcomes, and laboratory effects of prothrombin complex concentrate

Endogenous sex hormones and risk of venous thromboembolism in young women

Evidence-based approach to thrombophilia testing

Guidance for the treatment and prevention of obstetric-associated venous thromboembolism

Heart rate variability and first cardiovascular event in populations without known cardiovascular disease: meta-analysis and dose-response meta-regression

Imaging for the exclusion of pulmonary embolism in pregnancy

Imaging for the exclusion of pulmonary embolism in pregnancy.

Incidence of postpartum haemorrhage in women receiving therapeutic doses of low-molecular-weight heparin: results of a retrospective cohort study

Incidence of venous thromboembolism in hospitalized patients with COVID-19

Inherited thrombophilia and pregnancy complications revisited.

Inherited thrombophilias

Introduction to the analysis of next generation sequencing data and its application to venous thromboembolism.

Is Thrombophilia Testing Useful? ⬇️

Low-molecular-weight heparin and recurrent placenta-mediated pregnancy complications: a meta-analysis of individual patient data from randomised controlled trials.

Low-molecular-weight heparin for prevention of placenta-mediated pregnancy complications: protocol for a systematic review and individual patient data meta-analysis (AFFIRM).

Mechanistic View of Risk Factors for Venous Thromboembolism ⬇️

Nasal Levels of Antimicrobial Peptides in Allergic Asthma Patients and Healthy Controls: Differences and Effect of a Short 1,25(OH)2 Vitamin D3 Treatment

Oral contraceptives and the risk of venous thromboembolism

Parenteral anticoagulation for prolonging survival in patients with cancer who have no other indication for anticoagulation

Parenteral anticoagulation in ambulatory patients with cancer

Parenteral anticoagulation in patients with cancer who have no therapeutic or prophylactic indication for anticoagulation

Parenteral anticoagulation in patients with cancer who have no therapeutic or prophylactic indication for anticoagulation

Parenteral anticoagulation may prolong the survival of patients with limited small cell lung cancer: a Cochrane systematic review

Pregnancy failure and heritable thrombophilia

Prognostic characteristics and body mass index in patients with pulmonary embolism: does size matter?

Prophylaxis for venous thromboembolism during asparaginase therapy in patients treated for acute lymphoblastic leukemia

Prophylaxis for venous thromboembolism during asparaginase therapy in patients treated for acute lymphoblastic leukemia

Pulmonary embolism at autopsy in cancer patients

RSA prediction of high failure rate for the uncoated Interax TKA confirmed by meta-analysis

Relevance of the JAK2V617F mutation in patients with deep vein thrombosis of the leg ⬇️

Reproducibility of exhaled nitric oxide measurements in overweight and obese adults

Risk Factors for Cerebral Venous Thrombosis.

Sex matters: Practice 5P's when treating young women with venous thromboembolism

Sex-specific differences in the distal versus proximal presenting location of acute deep vein thrombosis

The Netherlands Epidemiology of Obesity (NEO) study: study design and data collection

The absolute risk of venous thrombosis after air travel: a cohort study of 8,755 employees of international organisations

The prothrombin time does not predict the risk of recurrent venous thromboembolism or major bleeding in rivaroxaban-treated patients

The risk of venous thrombosis after air travel: contribution of clinical risk factors

Thrombophilia and new anticoagulant drugs

Thrombophilia testing for prevention of recurrent venous thromboembolism

Thrombophilia testing for prevention of recurrent venous thromboembolism

Thrombophilia testing for prevention of recurrent venous thromboembolism

Thromboprophylaxis in pregnant women: For whom and which LMWH dosage?

Thrombosis and hemostasis health in pregnancy: Registries from the International Society on Thrombosis and Haemostasis

Transgender patients and the role of the coagulation clinician

Treatment for superficial thrombophlebitis of the leg

Treatment for superficial thrombophlebitis of the leg

Treatment for superficial thrombophlebitis of the leg

Treatment of lower extremity superficial thrombophlebitis