List of works - Anastassis Perrakis

Automated protein model building combined with iterative structure refinement

scientific article (publication date: May 1999)

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

scientific article (publication date: 2008)

Developments in the CCP4 molecular-graphics project

scientific article (publication date: December 2004)

The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch

scientific article

RNA-binding protein Dnd1 inhibits microRNA access to target mRNA

scientific article

ARP/wARP and automatic interpretation of protein electron density maps

scientific article (publication date: 2003)

wARP: improvement and extension of crystallographic phases by weighted averaging of multiple-refined dummy atomic models

scientific article (publication date: July 1997)

ARP/wARP and molecular replacement

scientific article (publication date: October 2001)

The PDB_REDO server for macromolecular structure model optimization

scientific article

Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b

scientific article

A new generation of crystallographic validation tools for the protein data bank

scientific article

Crystal structure of a bacterial chitinase at 2.3 A resolution

scientific article

Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay-Sachs disease

scientific article

Towards rationalization of crystallization screening for small- to medium-sized academic laboratories: the PACT/JCSG+ strategy

scientific article published on 28 September 2005

Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery

scientific article

Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers

scientific article (publication date: July 2002)

Structure of a cephalosporin synthase

scientific article

Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase

scientific article

Structural basis of substrate discrimination and integrin binding by autotaxin

scientific article

CELL DIVISION CYCLE. Competition between MPS1 and microtubules at kinetochores regulates spindle checkpoint signaling

scientific article published on 11 June 2015

Towards complete validated models in the next generation of ARP/wARP

scientific article (publication date: December 2004)

PDB_REDO: constructive validation, more than just looking for errors

scientific article published on 16 March 2012

Breaking good resolutions with ARP/wARP.

scientific article published on 28 November 2003

Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate

scientific article (publication date: 3 June 2005)

ARP/wARP and molecular replacement: the next generation

scientific article published on 05 December 2007

ARP/wARP's model-building algorithms. I. The main chain

article

Structures of Escherichia coli DNA mismatch repair enzyme MutS in complex with different mismatches: a common recognition mode for diverse substrates

scientific article

Substrate-Assisted Catalysis Unifies Two Families of Chitinolytic Enzymes

scientific article published in 1997

Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system

scientific article

A TPR domain–containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B

scientific article

Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation

scientific article (publication date: 4 March 2003)

Glucosylated hydroxymethyluracil, DNA base J, prevents transcriptional readthrough in Leishmania

scientific article

The vertebrate mitotic checkpoint protein BUBR1 is an unusual pseudokinase.

scientific article published in June 2012

Small is beautiful: protein micro-crystallography

scientific article published in August 1998

Automatic rebuilding and optimization of crystallographic structures in the Protein Data Bank

scientific article

Insights into autotaxin: how to produce and present a lipid mediator

scientific article published on 14 September 2011

Crystal structure of the specific DNA-binding domain of Tc3 transposase of C.elegans in complex with transposon DNA.

scientific article published on October 1997

Co-expression of protein complexes in prokaryotic and eukaryotic hosts: experimental procedures, database tracking and case studies

scientific article published on 19 September 2006

PLA2G16 represents a switch between entry and clearance of Picornaviridae

scientific journal article

The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase.

scientific article published on 27 March 2007

Protein microcrystals and the design of a microdiffractometer: current experience and plans at EMBL and ESRF/ID13

scientific article published on 01 October 1999

Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence

scientific article

Autotaxin: structure-function and signaling

scientific article

Crystal structure of the targeting endonuclease of the human LINE-1 retrotransposon

scientific article

Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases

scientific article published on 29 March 2011

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing

scientific article

Evolutionary divergence and conservation of trypsin

scientific article published on 01 January 1994

Eukaryotic expression: developments for structural proteomics.

scientific article published on 19 September 2006

Vasohibins encode tubulin detyrosinating activity

scientific article

Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis

scientific article

List of works by Anastassis Perrakis

Automated protein model building combined with iterative structure refinement

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

Developments in the CCP4 molecular-graphics project

The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch

RNA-binding protein Dnd1 inhibits microRNA access to target mRNA

ARP/wARP and automatic interpretation of protein electron density maps

wARP: improvement and extension of crystallographic phases by weighted averaging of multiple-refined dummy atomic models

ARP/wARP and molecular replacement

The PDB_REDO server for macromolecular structure model optimization

Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b

A new generation of crystallographic validation tools for the protein data bank

Crystal structure of a bacterial chitinase at 2.3 A resolution

Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay-Sachs disease

Towards rationalization of crystallization screening for small- to medium-sized academic laboratories: the PACT/JCSG+ strategy

Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery

Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers

Structure of a cephalosporin synthase

Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase

Structural basis of substrate discrimination and integrin binding by autotaxin

CELL DIVISION CYCLE. Competition between MPS1 and microtubules at kinetochores regulates spindle checkpoint signaling

Towards complete validated models in the next generation of ARP/wARP

PDB_REDO: constructive validation, more than just looking for errors

Breaking good resolutions with ARP/wARP.

Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate

ARP/wARP and molecular replacement: the next generation

ARP/wARP's model-building algorithms. I. The main chain

Structures of Escherichia coli DNA mismatch repair enzyme MutS in complex with different mismatches: a common recognition mode for diverse substrates

Substrate-Assisted Catalysis Unifies Two Families of Chitinolytic Enzymes

Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system

A TPR domain–containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B

Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation

Glucosylated hydroxymethyluracil, DNA base J, prevents transcriptional readthrough in Leishmania

The vertebrate mitotic checkpoint protein BUBR1 is an unusual pseudokinase.

Small is beautiful: protein micro-crystallography

Automatic rebuilding and optimization of crystallographic structures in the Protein Data Bank

Insights into autotaxin: how to produce and present a lipid mediator

Crystal structure of the specific DNA-binding domain of Tc3 transposase of C.elegans in complex with transposon DNA.

Co-expression of protein complexes in prokaryotic and eukaryotic hosts: experimental procedures, database tracking and case studies

PLA2G16 represents a switch between entry and clearance of Picornaviridae

The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase.

Protein microcrystals and the design of a microdiffractometer: current experience and plans at EMBL and ESRF/ID13

Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence

Autotaxin: structure-function and signaling

Crystal structure of the targeting endonuclease of the human LINE-1 retrotransposon

Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing

Evolutionary divergence and conservation of trypsin

Eukaryotic expression: developments for structural proteomics.

Vasohibins encode tubulin detyrosinating activity

Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis