List of works - Sarah Picaud

3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands

scientific article

A series of potent CREBBP bromodomain ligands reveals an induced-fit pocket stabilized by a cation-π interaction

scientific article published on 12 May 2014

Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family

scientific article

Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery

scientific article published in 2011

Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains

scientific article (publication date: 2 July 2014)

Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening

scientific article

Dual kinase-bromodomain inhibitors for rationally designed polypharmacology

scientific article

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy

scientific article

Histone recognition and large-scale structural analysis of the human bromodomain family

scientific article

Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit

scientific article

Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment Hit

scientific article

Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands

scientific article

PFI-1, a highly selective protein interaction inhibitor, targeting BET Bromodomains

scientific article

Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.

scientific article published on 12 October 2016

RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain

scientific article

Selective inhibition of BET bromodomains

scientific article

Small-molecule inhibition of BRDT for male contraception

scientific article

Stimulation of Hepatic Apolipoprotein A-I Production by Novel Thieno-Triazolodiazepines: Roles of the Classical Benzodiazepine Receptor, PAF Receptor, and Bromodomain Binding

scientific article published on 22 December 2013

The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains

scientific article published on January 2013

[1,2,4]triazolo[4,3-a]phthalazines: inhibitors of diverse bromodomains

scientific article

List of works by Sarah Picaud

3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands

A series of potent CREBBP bromodomain ligands reveals an induced-fit pocket stabilized by a cation-π interaction

Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family

Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery

Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains

Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening

Dual kinase-bromodomain inhibitors for rationally designed polypharmacology

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy

Histone recognition and large-scale structural analysis of the human bromodomain family

Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit

Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment Hit

Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands

PFI-1, a highly selective protein interaction inhibitor, targeting BET Bromodomains

Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.

RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain

Selective inhibition of BET bromodomains

Small-molecule inhibition of BRDT for male contraception

Stimulation of Hepatic Apolipoprotein A-I Production by Novel Thieno-Triazolodiazepines: Roles of the Classical Benzodiazepine Receptor, PAF Receptor, and Bromodomain Binding

The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains

[1,2,4]triazolo[4,3-a]phthalazines: inhibitors of diverse bromodomains