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List of works by Stephen Higgs

A Critical Role for Induced IgM in the Protection against West Nile Virus Infection

scientific article

A Recombinant Subunit Based Zika Virus Vaccine Is Efficacious in Non-human Primates

scholarly article by Liana O Medina et al published 2018 in Frontiers in Immunology

A hamster-derived West Nile virus strain is highly attenuated and induces a differential proinflammatory cytokine response in two murine cell lines ⬇️

scientific article published on May 10, 2012

A new mouse model of autoimmune ocular myasthenia gravis

scientific article published in November 2007

A nonhuman primate model of chikungunya disease

scientific article

A novel mosquito ubiquitin targets viral envelope protein for degradation and reduces virion production during dengue virus infection

scientific article

A single amino acid substitution in the central portion of the West Nile virus NS4B protein confers a highly attenuated phenotype in mice.

scientific article

A single mutation in chikungunya virus affects vector specificity and epidemic potential

scientific article published in December 2007

A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection

scientific article

Aedes aegypti saliva alters leukocyte recruitment and cytokine signaling by antigen-presenting cells during West Nile virus infection

scientific article

Aedes aegypti salivary gland extracts modulate anti-viral and TH1/TH2 cytokine responses to sindbis virus infection

scientific article

Aedes albopictus (Diptera: Culicidae) and Mosquito-Borne Viruses in the United States

scientific article published on 25 April 2016

Alterations in the Aedes aegypti transcriptome during infection with West Nile, dengue and yellow fever viruses

scientific article

An immune-responsive serpin, SRPN6, mediates mosquito defense against malaria parasites

scientific article

Anopheles gambiae heat shock protein cognate 70B impedes o'nyong-nyong virus replication

scientific article (publication date: 11 July 2007)

Antiviral activity of selected flavonoids against Chikungunya virus

scientific article published on 23 July 2016

Antiviral activity of silymarin against chikungunya virus

scientific article published on 16 June 2015

Application of a Nonpaper Based Matrix to Preserve Chikungunya Virus Infectivity at Ambient Temperature

scientific article published on 15 March 2018

Arbovirus-Mosquito Vector-Host Interactions and the Impact on Transmission and Disease Pathogenesis of Arboviruses

article

Association of the Host Immune Response with Protection Using a Live Attenuated African Swine Fever Virus Model

scientific article published on 22 October 2016

Biological Control Strategies for Mosquito Vectors of Arboviruses

scientific article published on 10 February 2017

Characterization of an endogenous gene expressed in Aedes aegypti using an orally infectious recombinant Sindbis virus

scientific article

Characterization of an infectious clone of the wild-type yellow fever virus Asibi strain that is able to infect and disseminate in mosquitoes

scientific article

Characterization of the antigen distribution and tissue tropisms of three phenotypically distinct yellow fever virus variants in orally infected Aedes aegypti mosquitoes

scientific article

Chikungunya virus adaptation to Aedes albopictus mosquitoes does not correlate with acquisition of cholesterol dependence or decreased pH threshold for fusion reaction ⬇️

scientific article published on July 29, 2011

Chikungunya virus adapts to tiger mosquito via evolutionary convergence: a sign of things to come?

scientific article

Chikungunya virus and its mosquito vectors

scientific article

Chikungunya virus arthritis in adult wild-type mice

scientific article

Chikungunya virus emergence is constrained in Asia by lineage-specific adaptive landscapes

scientific article

Chikungunya virus: a major emerging threat

scientific article published on 16 July 2014

Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes

scientific article

Chikungunya: here today, where tomorrow?

scientific article published in January 2015

Chikungunya: international focus issue

scientific article published on April 2015

Circulating immune complexes augment severity of antibody-mediated myasthenia gravis in hypogammaglobulinemic RIIIS/J mice

scientific article published in May 2004

Clara Southmayd Ludlow: Her Thirst for Knowledge was Positively Inspirational: Honoring a Female Giant in Tropical Medicine

scientific article

Comparative sensitivity of the VecTest antigen-capture assay, reverse transcriptase-PCR, and cell culture for detection of West Nile virus in dead birds

scientific article published on January 2004

Contribution of Vaccination to the Reduction of Infectious Mortality in Ukraine in the Second Half of the 20th and Early 21st Century: A Comparative Population Based Study of the Dynamics and Structure of Infectious Mortality and Incidence

article

Corrigendum: Zika viral dynamics and shedding in rhesus and cynomolgus macaques

scientific article published on February 2017

Culex Species Mosquitoes and Zika Virus

scientific article

Culex tarsalis is a competent vector species for Cache Valley virus

scholarly article published by Alain Kohl in 2018

Deciphering the potential of baicalin as an antiviral agent for Chikungunya virus infection

scientific article published on 18 December 2017

Deliberate attenuation of chikungunya virus by adaptation to heparan sulfate-dependent infectivity: a model for rational arboviral vaccine design

scientific article

Dengue Virus Infection of Aedes aegypti Requires a Putative Cysteine Rich Venom Protein

scientific article published on 22 October 2015

Determinants of vector specificity of o'nyong nyong and chikungunya viruses in Anopheles and Aedes mosquitoes

scientific article published in April 2006

Development and characterization of a double subgenomic chikungunya virus infectious clone to express heterologous genes in Aedes aegypti mosquitoes

scientific article published in October 2005

Differential Infectivities among Different Japanese Encephalitis Virus Genotypes in Culex quinquefasciatus Mosquitoes

scientific article

Differential infectivities of o'nyong-nyong and chikungunya virus isolates in Anopheles gambiae and Aedes aegypti mosquitoes

scientific article

Differential outcomes of Zika virus infection in Aedes aegypti orally challenged with infectious blood meals and infectious protein meals

scientific article published on 10 August 2017

Editorial and commentary on the guidance document for the contained field trials of engineered mosquitoes

scientific article published in April 2008

Effective suppression of Dengue fever virus in mosquito cell cultures using retroviral transduction of hammerhead ribozymes targeting the viral genome

scientific article

Effective suppression of dengue virus using a novel group-I intron that induces apoptotic cell death upon infection through conditional expression of the Bax C-terminal domain

scientific article published on 13 June 2014

Emergence and re-emergence of mosquito-borne arboviruses

scientific article published on 8 February 2019

Emerging arboviruses: Why today?

scientific article published on July 2017

Endocytosis of chikungunya virus into mammalian cells: role of clathrin and early endosomal compartments

scientific article

Envelope protein glycosylation status influences mouse neuroinvasion phenotype of genetic lineage 1 West Nile virus strains

scientific article

Epistatic Roles of E2 Glycoprotein Mutations in Adaption of Chikungunya Virus to Aedes Albopictus and Ae. Aegypti Mosquitoes

scientific article

Evaluation of Simultaneous Transmission of Chikungunya Virus and Dengue Virus Type 2 in Infected Aedes aegypti and Aedes albopictus (Diptera: Culicidae)

scientific article

Evaluation of the function of a type I peritrophic matrix as a physical barrier for midgut epithelium invasion by mosquito-borne pathogens in Aedes aegypti

scientific article (publication date: October 2008)

Evidence-Based Policies on Migration and Global Health are Essential to Maintain the Health of Those Inside and Outside the United States

scientific article published on January 2017

Experimental transmission of Mayaro virus by Aedes aegypti

scientific article

Flavivirus-mosquito interactions

scientific article

Genetic Evidence for Involvement of Classical Complement Pathway in Induction of Experimental Autoimmune Myasthenia Gravis ⬇️

scientific article published on October 1, 2003

Genetic evidence for the involvement of Fcgamma receptor III in experimental autoimmune myasthenia gravis pathogenesis

scientific article published on 09 March 2006

Genetic variation of St. Louis encephalitis virus

scientific article

Genome-scale phylogenetic analyses of chikungunya virus reveal independent emergences of recent epidemics and various evolutionary rates

scientific article published on 21 April 2010

Growth characteristics of ChimeriVax-Den vaccine viruses in Aedes aegypti and Aedes albopictus from Thailand.

scientific article published on November 2006

Host immune response to mosquito-transmitted chikungunya virus differs from that elicited by needle inoculated virus

scientific article

ISG15 is critical in the control of Chikungunya virus infection independent of UbE1L mediated conjugation

scientific article

Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus

scientific article

Impact of Wolbachia on infection with chikungunya and yellow fever viruses in the mosquito vector Aedes aegypti

scientific article

In VivoImaging of Chikungunya Virus in Mice andAedesMosquitoes Using aRenillaLuciferase Clone ⬇️

scientific article published on July 18, 2011

In memoriam--Richard M. Elliott (1954-2015)

scientific article

Infection of myofibers contributes to increased pathogenicity during infection with an epidemic strain of chikungunya virus

scientific article

Infection ofAedes albopictuswith Chikungunya Virus Rectally Administered by Enema ⬇️

scientific article published on December 18, 2012

Infection, dissemination, and transmission of a West Nile virus green fluorescent protein infectious clone by Culex pipiens quinquefasciatus mosquitoes

scientific article

Infectious clones of Chikungunya virus (La Réunion isolate) for vector competence studies

scientific article

Inhibition of luciferase expression in transgenic Aedes aegypti mosquitoes by Sindbis virus expression of antisense luciferase RNA

scientific article

Introduction to Special Issue on Pathogens in China

article

It Is Official: Vector-Borne and Zoonotic Diseases in the United States and Territories on the Rise-Now What?

Journal policy on names of aedine mosquito genera and subgenera

scientific article published in January 2005

LARVAL COMPETITION DIFFERENTIALLY AFFECTS ARBOVIRUS INFECTION IN AEDES MOSQUITOES

scientific article (publication date: December 2005)

Limited evolution of West Nile virus has occurred during its southwesterly spread in the United States

scientific article

Manipulation of the yellow fever virus non-structural genes 2A and 4B and the 3'non-coding region to evaluate genetic determinants of viral dissemination from the Aedes aegypti midgut.

scientific article published on December 2006

Mutagenesis analysis of T380R mutation in the envelope protein of yellow fever virus

scientific article published on 29 March 2014

Mutational analysis of the West Nile virus NS4B protein ⬇️

scientific article published on February 6, 2012

Nonviremic transmission of West Nile virus

scientific article (publication date: 21 June 2005)

Nonviremic transmission of West Nile virus: evaluation of the effects of space, time, and mosquito species.

scientific article published on March 2007

North American Culex pipiens and Culex quinquefasciatus are competent vectors for Usutu virus

North American domestic pigs are susceptible to experimental infection with Japanese encephalitis virus.

scientific article

Oral transmission of West Nile virus in a hamster model.

scientific article published on March 2005

Pathogen-derived resistance to dengue type 2 virus in mosquito cells by expression of the premembrane coding region of the viral genome

scientific article

Pathogenomics of Culex quinquefasciatus and meta-analysis of infection responses to diverse pathogens

scientific article

Photochemical Inactivation of Chikungunya Virus in Human Apheresis Platelet Components by Amotosalen and UVA Light ⬇️

scientific article published on March 25, 2013

Photochemical inactivation of chikungunya virus in plasma and platelets using the Mirasol pathogen reduction technology system

scientific article published on 25 May 2012

Potential arbovirus emergence and implications for the United Kingdom

scientific article

Potentiation of West Nile encephalitis by mosquito feeding

scientific article

Preclinical and clinical development of YFV 17D-based chimeric vaccines against dengue, West Nile and Japanese encephalitis viruses

scientific article published on 04 October 2009

President's Address (November 2016): American Society of Tropical Medicine and Hygiene

scientific article

Prior Exposure to Zika Virus Significantly Enhances Peak Dengue-2 Viremia in Rhesus Macaques

scientific article published on 5 September 2017

Prior exposure to uninfected mosquitoes enhances mortality in naturally-transmitted West Nile virus infection

scientific article

RNA interference-mediated knockdown of a GATA factor reveals a link to anautogeny in the mosquito Aedes aegypti

scientific article published on 31 October 2003

Rapid development of a DNA vaccine for Zika virus

scientific article

Real-time reverse transcriptase-polymerase chain reaction quantification of West Nile virus transmitted by Culex pipiens quinquefasciatus.

scientific article published on July 2004

Recombinant chimeric virus with wild-type dengue 4 virus premembrane and envelope and virulent yellow fever virus Asibi backbone sequences is dramatically attenuated in nonhuman primates

scientific article

Relative susceptibilties of South Texas mosquitoes to infection with West Nile virus

scientific article published in November 2007

Replication cycle of chikungunya: a re-emerging arbovirus

scientific article

Retraction. Detection and identification of Ehrlichia species in Rhipicephalus (Boophilus) microplus ticks in cattle from Xiamen, China

scientific article published on 01 March 2011

Role of the yellow fever virus structural protein genes in viral dissemination from the Aedes aegypti mosquito midgut

scientific article published on October 2006

Safety of flavivirus chimeric vaccines: answer to Ishikawa et al. [Vaccine 26 (22) (2008) 2772-2781].

scientific article published on 9 June 2008

Salivary gland morphology and virus transmission during long-term cytopathologic West Nile virus infection in Culex mosquitoes.

scientific article published on January 2007

Sequencing of Culex quinquefasciatus establishes a platform for mosquito comparative genomics

scientific article

Shedding of Japanese Encephalitis Virus in Oral Fluid of Infected Swine.

scientific article

Short report: comparison of oral infectious dose of West Nile virus isolates representing three distinct genotypes in Culex quinquefasciatus

scientific article (publication date: December 2008)

Simultaneous Coinfection of Macaques with Zika and Dengue Viruses Does not Enhance Acute Plasma Viremia but Leads to Activation of Monocyte Subsets and Biphasic Release of Pro-inflammatory Cytokines

scientific article published on 27 May 2019

Size heterogeneity in the 3' noncoding region of South American isolates of yellow fever virus

scientific article

Stability of Yellow Fever Virus under Recombinatory Pressure as Compared with Chikungunya Virus ⬇️

scientific article published on August 3, 2011

Substitution of wild-type yellow fever Asibi sequences for 17D vaccine sequences in ChimeriVax-dengue 4 does not enhance infection of Aedes aegypti mosquitoes

scientific article (publication date: March 2008)

Susceptibility of a North American Culex quinquefasciatus to Japanese Encephalitis Virus

scientific article published on November 2015

Temperature Tolerance and Inactivation of Chikungunya Virus

scientific article

The (International) American Society of Tropical Medicine and Hygiene

scientific article published on November 2016

The 2002 introduction of West Nile virus into Harris County, Texas, an area historically endemic for St. Louis encephalitis

scientific article published on June 2004

The 2005-2006 Chikungunya epidemic in the Indian Ocean

scientific article published in January 2006

The Bridges and Blockades to Evolutionary Convergence on the Road to Predicting Chikungunya Virus Evolution

scientific article published on September 2017

The Discovery of Arthropod-Specific Viruses in Hematophagous Arthropods: An Open Door to Understanding the Mechanisms of Arbovirus and Arthropod Evolution?

scientific article published in January 2018

The Universal Standard for Safe and Secure Work with Arthropod Vectors: The American Committee of Medical Entomology's Arthropod Containment Guidelines

scholarly article published by Stephen Higgs in 2019

The enhancement of arbovirus transmission and disease by mosquito saliva is associated with modulation of the host immune response

scientific article

The potential for West Nile virus to establish outside of its natural range: a consideration of potential mosquito vectors in the United Kingdom

scientific article published on February 2004

The potential for the establishment of new arbovirus transmission cycles in Europe

scientific article

The role of phenylalanine hydroxylase in melanotic encapsulation of filarial worms in two species of mosquitoes

scientific article published on December 2004

Transcriptome changes in Culex quinquefasciatus (Diptera: Culicidae) salivary glands during West Nile virus infection

scientific article published on May 2010

Type I IFN controls chikungunya virus via its action on nonhematopoietic cells

scientific article

Ultrastructural study of West Nile virus pathogenesis in Culex pipiens quinquefasciatus (Diptera: Culicidae).

scientific article

Vector competence of Australian mosquitoes for yellow fever virus

scientific article

Vector-borne and zoonotic diseases continues its growth

scientific article published in January 2011

Virus-specific thermostability and heat inactivation profiles of alphaviruses

scientific article

Viruses of the family Bunyaviridae: are all available isolates reassortants?

scientific article

West Nile virus dissemination and tissue tropisms in orally infected Culex pipiens quinquefasciatus

scientific article

West Nile virus: where are we now?

scientific article published in September 2004

Year-round West Nile virus activity, Gulf Coast region, Texas and Louisiana

scientific article published in September 2004

Yellow Fever Virus: Cause for Concern or Alarm?

scientific article published on 11 July 2016

Yellow fever virus infectivity for Bolivian Aedes aegypti mosquitoes

scientific article published in September 2004

Yellow fever virus susceptibility of two mosquito vectors from Kenya, East Africa ⬇️

scientific article published on April 20, 2012

Yellow fever: a disease that has yet to be conquered

scientific article

Zika Virus: Emergence and Emergency

scientific article

Zika convalescent macaques display delayed induction of anmanestic cross-neutralizing antibody responses after dengue infection.

scientific article published on 13 July 2018

Zika viral dynamics and shedding in rhesus and cynomolgus macaques

scientific article (publication date: December 2016)

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

scientific article

pH-Dependent entry of chikungunya virus fusion into mosquito cells

scientific article

trans-Packaged West Nile virus-like particles: infectious properties in vitro and in infected mosquito vectors

scientific article

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