List of works - Vadim Cherezov

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

scientific article

A novel inert crystal delivery medium for serial femtosecond crystallography.

scientific article published on 30 June 2015

Agonist-bound structure of the human P2Y12 receptor

scientific article

Allosteric sodium in class A GPCR signaling

scientific article

An outlook on using serial femtosecond crystallography in drug discovery

scientific article published on 11 June 2019

Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes

scientific article

Author Correction: Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs

scientific article published on 23 November 2020

Biophysical and transfection studies of the diC(14)-amidine/DNA complex

scientific article

Characterization of lipid matrices for membrane protein crystallization by high-throughput small angle X-ray scattering

scientific article published on 27 August 2011

Conserved Binding Mode of Human β 2 Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography

scientific article

Crystal Structure of a Voltage-gated K+ Channel Pore Module in a Closed State in Lipid Membranes

scientific article

Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. coli and Enteropathogenic Y. pseudotuberculosis

scientific article

Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand

scientific article

Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor

scientific article published on 03 December 2018

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

scientific article

Crystallization and preliminary X-ray diffraction analysis of a soluble domain of the putative zinc transporter CzrB from Thermus thermophilus

scientific article published on 21 July 2007

Crystallization of membrane proteins in lipidic mesophases

scientific article

Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases ⬇️

scientific article published on April 6, 2011

Diversity and modularity of G protein-coupled receptor structures

scientific article

Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists

scientific article published on 27 November 2019

Fast iodide-SAD phasing for high-throughput membrane protein structure determination

scientific article

Femtosecond crystallography of membrane proteins in the lipidic cubic phase

scientific article

Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors

scientific article

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

scientific article

GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles ⬇️

scientific article published on October 21, 2011

GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014.

scientific article published on 14 March 2015

Generic GPCR residue numbers - aligning topology maps while minding the gaps

scientific article

Harnessing the power of an X-ray laser for serial crystallography of membrane proteins crystallized in lipidic cubic phase

scientific article published on 15 October 2020

High Resolution Structure of the ba3 Cytochrome c Oxidase from Thermus thermophilus in a Lipidic Environment

scientific article

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

scientific article

High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions.

scientific article published on 4 January 2018

High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source

article

Hydrogen bonding of cholesterol in the lipidic cubic phase.

scientific article

In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin

scientific article

In meso structure of the cobalamin transporter, BtuB, at 1.95 A resolution

scientific article

Insights into the Mode of Action of a Putative Zinc Transporter CzrB in Thermus thermophilus

scientific article

Integrated nonlinear optical imaging microscope for on-axis crystal detection and centering at a synchrotron beamline

scientific article

Interaction of Cholesterol with a Docosahexaenoic Acid-Containing Phosphatidylethanolamine: Trigger for Microdomain/Raft Formation? ⬇️

scientific article published on October 21, 2003

LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment

scientific article

Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

scientific article

Lipidic cubic phase serial millisecond crystallography using synchrotron radiation

scientific article

Lipidic cubic phase technologies for membrane protein structural studies

scientific article

Membrane protein crystallization in lipidic mesophases with tailored bilayers

scientific article

Membrane protein crystallization in meso: lipid type-tailoring of the cubic phase

scientific article

Molecular control of δ-opioid receptor signalling

scientific article

Molecular organization of cholesterol in polyunsaturated membranes: microdomain formation

scientific article

Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.

scientific article

On the Origin of the Anomalous Behavior of Lipid Membrane Properties in the Vicinity of the Chain-Melting Phase Transition

scientific article published on 01 April 2020

Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography

scientific article

Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography.

scientific article

Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor

scientific article published on 01 February 2019

Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam.

scientific article

Recent progress in the structure determination of GPCRs, a membrane protein family with high potential as pharmaceutical targets

scientific article

Serial Femtosecond Crystallography of G Protein-Coupled Receptors

scientific article

Serial Femtosecond Crystallography of Membrane Proteins

scientific article

Serial femtosecond X-ray diffraction of enveloped virus microcrystals

scientific article published in July 2015

Serial femtosecond crystallography datasets from G protein-coupled receptors

scientific article

Serial femtosecond crystallography of soluble proteins in lipidic cubic phase.

scientific article

Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation

scientific article published on 24 May 2017

Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity

scientific article published on 04 May 2020

Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs

scientific article published on 12 November 2020

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

scientific article

Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor

scientific article

Structural Basis for Molecular Recognition at Serotonin Receptors

scientific article

Structural Features for Functional Selectivity at Serotonin Receptors

scientific article

Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs

scientific article

Structural basis for bifunctional peptide recognition at human δ-opioid receptor

scientific article

Structural basis for selectivity and diversity in angiotensin II receptors

scientific article

Structural basis of ligand recognition at the human MT1 melatonin receptor

scientific article published on 24 April 2019

Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors

scientific article published on 06 December 2019

Structural basis of the activation of a metabotropic GABA receptor

scientific article published on 17 June 2020

Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine

scientific article

Structural insights into melatonin receptors

scientific article published on 06 November 2019

Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody

scientific article published on 17 July 2017

Structural insights on ligand recognition at the human leukotriene B4 receptor 1

scientific article published on 20 May 2021

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator

scientific article

Structure of an agonist-bound human A2A adenosine receptor

scientific article

Structure of the Angiotensin receptor revealed by serial femtosecond crystallography.

scientific article published on 23 April 2015

Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc Complex

scientific article

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

scientific article

Structure of the full-length glucagon class B G-protein-coupled receptor

scientific article

Structure of the human P2Y12 receptor in complex with an antithrombotic drug

scientific article

Structure of the human glucagon class B G-protein-coupled receptor

scientific article

Structure of the human histamine H1 receptor complex with doxepin

scientific article

Structure of the human smoothened receptor bound to an antitumour agent

scientific article

Structure of the human κ-opioid receptor in complex with JDTic

scientific article

Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic

scientific article

Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors

scientific article

Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs

scientific article published on 09 October 2019

Structure-function of the G protein-coupled receptor superfamily

scientific article

Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

scientific article

Ternary structure reveals mechanism of a membrane diacylglycerol kinase

scientific article

The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

scientific article

The GPCR Network: a large-scale collaboration to determine human GPCR structure and function

scientific article published on 14 December 2012

The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor

scientific article

Too hot to handle? Synchrotron X-ray damage of lipid membranes and mesophases

scientific article

Toward G protein-coupled receptor structure-based drug design using X-ray lasers

scientific article published on 24 October 2019

Towards protein-crystal centering using second-harmonic generation (SHG) microscopy

scientific article

Transmembrane peptides stabilize inverted cubic phases in a biphasic length-dependent manner: implications for protein-induced membrane fusion

scientific article

Two classes of cholesterol binding sites for the β2AR revealed by thermostability and NMR.

scientific article

Two disparate ligand-binding sites in the human P2Y1 receptor

scientific article

Virtual discovery of melatonin receptor ligands to modulate circadian rhythms

scientific article published on 10 February 2020

X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex

scientific article

XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia

scientific article published on 28 February 2020

XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity

scientific article published on 24 April 2019

List of works by Vadim Cherezov

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

A novel inert crystal delivery medium for serial femtosecond crystallography.

Agonist-bound structure of the human P2Y12 receptor

Allosteric sodium in class A GPCR signaling

An outlook on using serial femtosecond crystallography in drug discovery

Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes

Author Correction: Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs

Biophysical and transfection studies of the diC(14)-amidine/DNA complex

Characterization of lipid matrices for membrane protein crystallization by high-throughput small angle X-ray scattering

Conserved Binding Mode of Human β 2 Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography

Crystal Structure of a Voltage-gated K+ Channel Pore Module in a Closed State in Lipid Membranes

Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. coli and Enteropathogenic Y. pseudotuberculosis

Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand

Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

Crystallization and preliminary X-ray diffraction analysis of a soluble domain of the putative zinc transporter CzrB from Thermus thermophilus

Crystallization of membrane proteins in lipidic mesophases

Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases ⬇️

Diversity and modularity of G protein-coupled receptor structures

Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists

Fast iodide-SAD phasing for high-throughput membrane protein structure determination

Femtosecond crystallography of membrane proteins in the lipidic cubic phase

Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles ⬇️

GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014.

Generic GPCR residue numbers - aligning topology maps while minding the gaps

Harnessing the power of an X-ray laser for serial crystallography of membrane proteins crystallized in lipidic cubic phase

High Resolution Structure of the ba3 Cytochrome c Oxidase from Thermus thermophilus in a Lipidic Environment

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions.

High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source

Hydrogen bonding of cholesterol in the lipidic cubic phase.

In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin

In meso structure of the cobalamin transporter, BtuB, at 1.95 A resolution

Insights into the Mode of Action of a Putative Zinc Transporter CzrB in Thermus thermophilus

Integrated nonlinear optical imaging microscope for on-axis crystal detection and centering at a synchrotron beamline

Interaction of Cholesterol with a Docosahexaenoic Acid-Containing Phosphatidylethanolamine: Trigger for Microdomain/Raft Formation? ⬇️

LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment

Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

Lipidic cubic phase serial millisecond crystallography using synchrotron radiation

Lipidic cubic phase technologies for membrane protein structural studies

Membrane protein crystallization in lipidic mesophases with tailored bilayers

Membrane protein crystallization in meso: lipid type-tailoring of the cubic phase

Molecular control of δ-opioid receptor signalling

Molecular organization of cholesterol in polyunsaturated membranes: microdomain formation

Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.

On the Origin of the Anomalous Behavior of Lipid Membrane Properties in the Vicinity of the Chain-Melting Phase Transition

Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography

Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography.

Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor

Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam.

Recent progress in the structure determination of GPCRs, a membrane protein family with high potential as pharmaceutical targets

Serial Femtosecond Crystallography of G Protein-Coupled Receptors

Serial Femtosecond Crystallography of Membrane Proteins

Serial femtosecond X-ray diffraction of enveloped virus microcrystals

Serial femtosecond crystallography datasets from G protein-coupled receptors

Serial femtosecond crystallography of soluble proteins in lipidic cubic phase.

Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation

Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity

Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor

Structural Basis for Molecular Recognition at Serotonin Receptors

Structural Features for Functional Selectivity at Serotonin Receptors

Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs

Structural basis for bifunctional peptide recognition at human δ-opioid receptor

Structural basis for selectivity and diversity in angiotensin II receptors

Structural basis of ligand recognition at the human MT1 melatonin receptor

Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors

Structural basis of the activation of a metabotropic GABA receptor

Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine

Structural insights into melatonin receptors

Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody

Structural insights on ligand recognition at the human leukotriene B4 receptor 1

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator

Structure of an agonist-bound human A2A adenosine receptor

Structure of the Angiotensin receptor revealed by serial femtosecond crystallography.

Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc Complex