List of works - Vsevolod Katritch

5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.

scientific article published on 19 January 2018

A Thieno[2,3-d]pyrimidine Scaffold is a Novel Negative Allosteric Modulator of the Dopamine D2 Receptor.

scientific article published on 23 April 2018

Activation Stoichiometry and Pore Architecture of TRPA1 Probed with Channel Concatemers

scientific article published in Scientific Reports

Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges

scientific article published on 24 July 2014

Agonist-bound structure of the human P2Y12 receptor

scientific article

Allosteric sodium in class A GPCR signaling

scientific article

Aminoglycoside binding in the major groove of duplex RNA: the thermodynamic and electrostatic forces that govern recognition

scientific article published on 01 April 2000

An autism spectrum disorder-related de novo mutation hotspot discovered in the GEF1 domain of Trio

scientific article published on 19 September 2017

Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes

scientific article

Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR.

scientific article published on 19 January 2012

Chemotype-selective modes of action of κ-opioid receptor agonists

scientific article published on 11 October 2013

Computational design for thermostabilization of GPCRs

scientific article published on 23 March 2019

Computational design of thermostabilizing point mutations for G protein-coupled receptors.

scientific article published on 21 June 2018

Conserved Binding Mode of Human β 2 Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography

scientific article

Crystal Structure of the Human Cannabinoid Receptor CB2

scientific article published on 10 January 2019

Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor

scientific article published on 03 December 2018

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

scientific article

Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor

scientific article

Design, synthesis, pharmacological characterization of a fluorescent agonist of the P2Y₁₄ receptor

scientific article

Determination of DNA persistence length by cryo-electron microscopy. Separation of the static and dynamic contributions to the apparent persistence length of DNA.

scientific article published on December 1995

Discovery of small molecule inhibitors of ubiquitin-like poxvirus proteinase I7L using homology modeling and covalent docking approaches

scientific article

Diversity and modularity of G protein-coupled receptor structures

scientific article

Dynamic Strategic Bond Analysis Yields a Ten-Step Synthesis of 20-nor-Salvinorin A, a Potent κ-OR Agonist

scientific article published on 13 December 2017

Electrophoretic mobility of DNA knots

scientific article published in Nature

Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists

scientific article published on 27 November 2019

Evaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound A₂A adenosine receptor

scientific article published on 12 December 2011

Exploring a 2-naphthoic acid template for the structure-based design of P2Y14 receptor antagonist molecular probes

scientific article

Expression and purification of an engineered human endothelin receptor B in a monomeric form

scientific article published on March 2016

Extrinsic Tryptophans as NMR Probes of Allosteric Coupling in Membrane Proteins: Application to the A2A Adenosine Receptor

scientific article published on 20 June 2018

Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors

scientific article

GPCR 3D homology models for ligand screening: lessons learned from blind predictions of adenosine A2a receptor complex

scientific article

GPCR agonist binding revealed by modeling and crystallography

scientific article published on 6 September 2011

Generic GPCR residue numbers - aligning topology maps while minding the gaps

scientific article

Genetically encoded chemical probes in cells reveal the binding path of urocortin-I to CRF class B GPCR

scientific journal article

Geometry and physics of catenanes applied to the study of DNA replication

scientific article

Geometry and physics of knots

scientific article published in Nature

Harnessing Ion-Binding Sites for GPCR Pharmacology

scientific article published on 01 October 2019

High Resolution Structure of the ba3 Cytochrome c Oxidase from Thermus thermophilus in a Lipidic Environment

scientific article

ICFF: a new method to incorporate implicit flexibility into an internal coordinate force field

scientific article published in January 2003

Identifying conformational changes of the beta(2) adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators

scientific article

In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin

scientific article

In vitro expression and analysis of the 826 human G protein-coupled receptors

scientific article published on 16 April 2016

Influence of nucleosome structure on the three-dimensional folding of idealized minichromosomes

Intracellular Transfer of Na+ in an Active-State G-Protein-Coupled Receptor.

scientific article published on 6 December 2017

Ligand binding and subtype selectivity of the human A(2A) adenosine receptor: identification and characterization of essential amino acid residues.

scientific article

Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX.

scientific article published on September 2011

Ligand-guided receptor optimization

scientific article published in January 2012

Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

scientific article

Modeling ligand recognition at the P2Y12 receptor in light of X-ray structural information

scientific article

Molecular control of δ-opioid receptor signalling

scientific article

Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.

scientific article

Nucleotides Acting at P2Y Receptors: Connecting Structure and Function

scientific article published on 2 April 2015

O-GlcNAc Engineering of GPCR Peptide-Agonists Improves Their Stability and in Vivo Activity

scientific article published on 16 August 2019

Opposite effect of counterions on the persistence length of nicked and non-nicked DNA.

scientific article published on March 1997

Optical Control of Cannabinoid Receptor 2-Mediated Ca<sup>2+</sup> Release Enabled by Synthesis of Photoswitchable Probes

scientific article published on 05 January 2021

Optimization of adenosine 5'-carboxamide derivatives as adenosine receptor agonists using structure-based ligand design and fragment screening

scientific article

Properties of ideal composite knots

scientific article published in July 1997

Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor

scientific article published on 01 February 2019

Pulling chromatin fibers: computer simulations of direct physical micromanipulations

Schizophrenia-associated SAP97 mutations increase glutamatergic synapse strength in the dentate gyrus and impair contextual episodic memory in rats

scientific article published in 2022

Sedimentation and electrophoretic migration of DNA knots and catenanes

scientific article

Serial Femtosecond Crystallography of G Protein-Coupled Receptors

scientific article

SimiCon: a web tool for protein-ligand model comparison through calculation of equivalent atomic contacts

scientific article

Single Amino Acid Variation Underlies Species-Specific Sensitivity to Amphibian Skin-Derived Opioid-like Peptides

scientific article

Single-molecule view of basal activity and activation mechanisms of the G protein-coupled receptor β2AR.

scientific article

Sodium ion binding pocket mutations and adenosine A2A receptor function.

scientific article published on 3 December 2014

Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment

scientific article published on August 2011

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

scientific article

Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor

scientific article

Structural Basis for Molecular Recognition at Serotonin Receptors

scientific article

Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling

scientific article published on 26 January 2018

Structural Features for Functional Selectivity at Serotonin Receptors

scientific article

Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs

scientific article

Structural basis for bifunctional peptide recognition at human δ-opioid receptor

scientific article

Structural basis for selectivity and diversity in angiotensin II receptors

scientific article

Structural basis of ligand recognition at the human MT1 melatonin receptor

scientific article published on 24 April 2019

Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors

scientific article published on 06 December 2019

Structural basis of the activation of a metabotropic GABA receptor

scientific article published on 17 June 2020

Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells.

scientific article

Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody

scientific article published on 17 July 2017

Structural insights on ligand recognition at the human leukotriene B4 receptor 1

scientific article published on 20 May 2021

Structure and Modeling of GPCRs: Implications for Drug Discovery

article published in 2010

Structure based prediction of subtype-selectivity for adenosine receptor antagonists

scientific article

Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator

scientific article

Structure of an agonist-bound human A2A adenosine receptor

scientific article

Structure of the Angiotensin receptor revealed by serial femtosecond crystallography.

scientific article published on 23 April 2015

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

scientific article

Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.

scientific article published on 3 January 2018

Structure of the human P2Y12 receptor in complex with an antithrombotic drug

scientific article

Structure of the human glucagon class B G-protein-coupled receptor

scientific article

Structure of the human histamine H1 receptor complex with doxepin

scientific article

Structure of the human smoothened receptor bound to an antitumour agent

scientific article

Structure of the human κ-opioid receptor in complex with JDTic

scientific article

Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic

scientific article

Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor

scientific article

Structure-Based Virtual Screening of Ultra-Large Library Yields Potent Antagonists for a Lipid GPCR

scientific article published on 03 December 2020

Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists

scientific article

Structure-based discovery of potent and selective melatonin receptor agonists

scientific article published on 02 March 2020

Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors

scientific article

Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs

scientific article published on 09 October 2019

Structure-function of the G protein-coupled receptor superfamily

scientific article

Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

scientific article

Synthesis of Photoswitchable Δ9-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling.

scientific article published on 21 November 2017

The GPCR Network: a large-scale collaboration to determine human GPCR structure and function

scientific article published on 14 December 2012

The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor

scientific article

The effect of intrinsic curvature on conformational properties of circular DNA.

scientific article

The role of a sodium ion binding site in the allosteric modulation of the A(2A) adenosine G protein-coupled receptor

scientific article

Tightness of random knotting

scientific article published on 01 May 2000

Two disparate ligand-binding sites in the human P2Y1 receptor

scientific article

XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity

scientific article published on 24 April 2019

List of works by Vsevolod Katritch

5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.

A Thieno[2,3-d]pyrimidine Scaffold is a Novel Negative Allosteric Modulator of the Dopamine D2 Receptor.

Activation Stoichiometry and Pore Architecture of TRPA1 Probed with Channel Concatemers

Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges

Agonist-bound structure of the human P2Y12 receptor

Allosteric sodium in class A GPCR signaling

Aminoglycoside binding in the major groove of duplex RNA: the thermodynamic and electrostatic forces that govern recognition

An autism spectrum disorder-related de novo mutation hotspot discovered in the GEF1 domain of Trio

Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes

Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR.

Chemotype-selective modes of action of κ-opioid receptor agonists

Computational design for thermostabilization of GPCRs

Computational design of thermostabilizing point mutations for G protein-coupled receptors.

Conserved Binding Mode of Human β 2 Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography

Crystal Structure of the Human Cannabinoid Receptor CB2

Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor

Design, synthesis, pharmacological characterization of a fluorescent agonist of the P2Y₁₄ receptor

Determination of DNA persistence length by cryo-electron microscopy. Separation of the static and dynamic contributions to the apparent persistence length of DNA.

Discovery of small molecule inhibitors of ubiquitin-like poxvirus proteinase I7L using homology modeling and covalent docking approaches

Diversity and modularity of G protein-coupled receptor structures

Dynamic Strategic Bond Analysis Yields a Ten-Step Synthesis of 20-nor-Salvinorin A, a Potent κ-OR Agonist

Electrophoretic mobility of DNA knots

Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists

Evaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound A₂A adenosine receptor

Exploring a 2-naphthoic acid template for the structure-based design of P2Y14 receptor antagonist molecular probes

Expression and purification of an engineered human endothelin receptor B in a monomeric form

Extrinsic Tryptophans as NMR Probes of Allosteric Coupling in Membrane Proteins: Application to the A2A Adenosine Receptor

Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors

GPCR 3D homology models for ligand screening: lessons learned from blind predictions of adenosine A2a receptor complex

GPCR agonist binding revealed by modeling and crystallography

Generic GPCR residue numbers - aligning topology maps while minding the gaps

Genetically encoded chemical probes in cells reveal the binding path of urocortin-I to CRF class B GPCR

Geometry and physics of catenanes applied to the study of DNA replication

Geometry and physics of knots

Harnessing Ion-Binding Sites for GPCR Pharmacology

High Resolution Structure of the ba3 Cytochrome c Oxidase from Thermus thermophilus in a Lipidic Environment

ICFF: a new method to incorporate implicit flexibility into an internal coordinate force field

Identifying conformational changes of the beta(2) adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators

In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin

In vitro expression and analysis of the 826 human G protein-coupled receptors

Influence of nucleosome structure on the three-dimensional folding of idealized minichromosomes

Intracellular Transfer of Na+ in an Active-State G-Protein-Coupled Receptor.

Ligand binding and subtype selectivity of the human A(2A) adenosine receptor: identification and characterization of essential amino acid residues.

Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX.

Ligand-guided receptor optimization

Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

Modeling ligand recognition at the P2Y12 receptor in light of X-ray structural information

Molecular control of δ-opioid receptor signalling

Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.

Nucleotides Acting at P2Y Receptors: Connecting Structure and Function

O-GlcNAc Engineering of GPCR Peptide-Agonists Improves Their Stability and in Vivo Activity

Opposite effect of counterions on the persistence length of nicked and non-nicked DNA.

Optical Control of Cannabinoid Receptor 2-Mediated Ca<sup>2+</sup> Release Enabled by Synthesis of Photoswitchable Probes

Optimization of adenosine 5'-carboxamide derivatives as adenosine receptor agonists using structure-based ligand design and fragment screening

Properties of ideal composite knots

Publisher Correction: Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor

Pulling chromatin fibers: computer simulations of direct physical micromanipulations

Schizophrenia-associated SAP97 mutations increase glutamatergic synapse strength in the dentate gyrus and impair contextual episodic memory in rats

Sedimentation and electrophoretic migration of DNA knots and catenanes

Serial Femtosecond Crystallography of G Protein-Coupled Receptors

SimiCon: a web tool for protein-ligand model comparison through calculation of equivalent atomic contacts

Single Amino Acid Variation Underlies Species-Specific Sensitivity to Amphibian Skin-Derived Opioid-like Peptides

Single-molecule view of basal activity and activation mechanisms of the G protein-coupled receptor β2AR.

Sodium ion binding pocket mutations and adenosine A2A receptor function.

Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor

Structural Basis for Molecular Recognition at Serotonin Receptors

Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling

Structural Features for Functional Selectivity at Serotonin Receptors

Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs

Structural basis for bifunctional peptide recognition at human δ-opioid receptor

Structural basis for selectivity and diversity in angiotensin II receptors

Structural basis of ligand recognition at the human MT1 melatonin receptor

Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors

Structural basis of the activation of a metabotropic GABA receptor

Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells.