List of works - Masoud Vedadi

A Strategy for Modulation of Enzymes in the Ubiquitin System

scientific article

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

scientific article

An allosteric inhibitor of protein arginine methyltransferase 3

scientific article

An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme

scientific article

Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

scientific article published on 26 May 2020

Characterization of 14-3-3 Proteins from Cryptosporidium parvum ⬇️

scientific article published on August 11, 2011

Crystal Structures of Human Choline Kinase Isoforms in Complex with Hemicholinium-3: SINGLE AMINO ACID NEAR THE ACTIVE SITE INFLUENCES INHIBITOR SENSITIVITY

scientific article

Crystal structure of the NADP+-dependent aldehyde dehydrogenase from Vibrio harveyi: structural implications for cofactor specificity and affinity

scientific article

Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder

scientific article

Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2

scientific article

Discovery of a 2,4-Diamino-7-aminoalkoxyquinazoline as a Potent and Selective Inhibitor of Histone Lysine Methyltransferase G9a

scientific article

Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor

scientific article

Discovery of a chemical probe for PRDM9

scientific article published on 17 December 2019

Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3

scientific article published on 08 July 2019

Glyoxylate and pyruvate are antagonistic effectors of the Escherichia coli IclR transcriptional regulator

scientific article

Human HDAC7 Harbors a Class IIa Histone Deacetylase-specific Zinc Binding Motif and Cryptic Deacetylase Activity

scientific article

In situ proteolysis for protein crystallization and structure determination

scientific article

Kinetic characterization of human histone H3 lysine 36 methyltransferases, ASH1L and SETD2

scientific article

L3MBTL1 recognition of mono- and dimethylated histones

scientific article

Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2

scientific article

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

scientific article published on 14 May 2020

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

scientific article

Recognition and Specificity Determinants of the Human Cbx Chromodomains

scientific article

SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination

scientific journal article

Sequence-specific recognition of a PxLPxI/L motif by an ankyrin repeat tumbler lock

scientific article

Sinefungin derivatives as inhibitors and structure probes of protein lysine methyltransferase SETD2

scientific article

Small-Molecule Ligands of Methyl-Lysine Binding Proteins

scientific article

Specificity of Campylobacter jejuni adhesin PEB3 for phosphates and structural differences among its ligand complexes

scientific article

Structural Biology of Human H3K9 Methyltransferases

scientific article

Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2

scientific article

Structural and chemical profiling of the human cytosolic sulfotransferases

scientific article

Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1

scientific article

Structural basis for molecular recognition and presentation of histone H3 by WDR5

scientific article

Structural basis of allele variation of human thiopurine-S-methyltransferase

scientific article

Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin

scientific article

Structural insights into the inhibited states of the Mer receptor tyrosine kinase

scientific article

Structural studies of a four-MBT repeat protein MBTD1

scientific article

Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations

scientific article

Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium

scientific article

The Cryptosporidium parvum Kinome ⬇️

scientific article

List of works by Masoud Vedadi

A Strategy for Modulation of Enzymes in the Ubiquitin System

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

An allosteric inhibitor of protein arginine methyltransferase 3

An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme

Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Characterization of 14-3-3 Proteins from Cryptosporidium parvum ⬇️

Crystal Structures of Human Choline Kinase Isoforms in Complex with Hemicholinium-3: SINGLE AMINO ACID NEAR THE ACTIVE SITE INFLUENCES INHIBITOR SENSITIVITY

Crystal structure of the NADP+-dependent aldehyde dehydrogenase from Vibrio harveyi: structural implications for cofactor specificity and affinity

Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder

Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2

Discovery of a 2,4-Diamino-7-aminoalkoxyquinazoline as a Potent and Selective Inhibitor of Histone Lysine Methyltransferase G9a

Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor

Discovery of a chemical probe for PRDM9

Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3

Glyoxylate and pyruvate are antagonistic effectors of the Escherichia coli IclR transcriptional regulator

Human HDAC7 Harbors a Class IIa Histone Deacetylase-specific Zinc Binding Motif and Cryptic Deacetylase Activity

In situ proteolysis for protein crystallization and structure determination

Kinetic characterization of human histone H3 lysine 36 methyltransferases, ASH1L and SETD2

L3MBTL1 recognition of mono- and dimethylated histones

Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

Recognition and Specificity Determinants of the Human Cbx Chromodomains

SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination

Sequence-specific recognition of a PxLPxI/L motif by an ankyrin repeat tumbler lock

Sinefungin derivatives as inhibitors and structure probes of protein lysine methyltransferase SETD2

Small-Molecule Ligands of Methyl-Lysine Binding Proteins

Specificity of Campylobacter jejuni adhesin PEB3 for phosphates and structural differences among its ligand complexes

Structural Biology of Human H3K9 Methyltransferases

Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2

Structural and chemical profiling of the human cytosolic sulfotransferases

Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1

Structural basis for molecular recognition and presentation of histone H3 by WDR5

Structural basis of allele variation of human thiopurine-S-methyltransferase

Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin

Structural insights into the inhibited states of the Mer receptor tyrosine kinase

Structural studies of a four-MBT repeat protein MBTD1

Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations

Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium

The Cryptosporidium parvum Kinome ⬇️