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Authors whose works are in public domain in at least one jurisdiction

List of works by Wolfram Tempel

(NZ)CH...O Contacts assist crystallization of a ParB-like nuclease

scientific article

A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1

scientific article

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

scientific article

A test of enhancing model accuracy in high-throughput crystallography

scientific article

An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene

scientific article

Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8

scientific article

Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation

scientific article

Away from the edge II: in-house Se-SAS phasing with chromium radiation

scientific article published on 24 June 2005

Bardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signaling

scientific article

Binding of Rac1, Rnd1, and RhoD to a Novel Rho GTPase Interaction Motif Destabilizes Dimerization of the Plexin-B1 Effector Domain

scientific article

Bromo-deaza-SAH: a potent and selective DOT1L inhibitor

scientific article published on 30 January 2013

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

scientific article

Certhrax Toxin, an Anthrax-related ADP-ribosyltransferase from Bacillus cereus ⬇️

scientific article published on September 19, 2012

Characterization of a corrinoid protein involved in the C1 metabolism of strict anaerobic bacterium Moorella thermoacetica

scientific article published in April 2007

Chromokinesins NOD and KID Use Distinct ATPase Mechanisms and Microtubule Interactions to Perform a Similar Function: Supplemental Info

Comparative Structural Analysis of Human DEAD-Box RNA Helicases

scientific article

Comprehensive Analysis of the Human SH3 Domain Family Reveals a Wide Variety of Non-canonical Specificities.

scientific article published on 28 August 2017

Correction: Structural and Chemical Profiling of the Human Cytosolic Sulfotransferases

scientific article

Crystal Structure of the N-Acetylmannosamine Kinase Domain of GNE

scientific article

Crystal Structures of Human Choline Kinase Isoforms in Complex with Hemicholinium-3: SINGLE AMINO ACID NEAR THE ACTIVE SITE INFLUENCES INHIBITOR SENSITIVITY

scientific article

Crystal structure of DPF3b in complex with an acetylated histone peptide

scientific article

Crystal structure of human eIF5A1: insight into functional similarity of human eIF5A1 and eIF5A2

scientific article

Crystal structure of human multiple copies in T‐cell lymphoma‐1 oncoprotein ⬇️

scientific article published on December 24, 2012

Crystal structure of the Cys2His2-type zinc finger domain of human DPF2

scientific article

Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N‐substituted pantothenamides ⬇️

scientific article published on July 2, 2013

Crystal structures of the Tudor domains of human PHF20 reveal novel structural variations on the Royal Family of proteins ⬇️

scientific article published on February 24, 2012

Crystal structures of the tetratricopeptide repeat domains of kinesin light chains: insight into cargo recognition mechanisms

scientific article (publication date: 2012)

Crystallization and preliminary X-ray analysis of GlcNAc alpha 1,4Gal-releasing endo-beta-galactosidase from Clostridium perfringens

scientific article published on 25 February 2004

Crystallization and preliminary X-ray diffraction analysis of lectin-1 from Pseudomonas aeruginosa

scientific article

Discovery of Potent Pantothenamide Inhibitors of Staphylococcus aureus Pantothenate Kinase through a Minimal SAR Study: Inhibition Is Due to Trapping of the Product

scientific article published on 3 August 2016

Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain

scientific article published on 6 January 2013

Erratum: A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

article

Erratum: Corrigendum: Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

scientific article published in Nature Communications

Erratum: Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

article

Family-wide Characterization of Histone Binding Abilities of Human CW Domain-containing Proteins

scientific article published on March 2016

First crystallographic models of human TBC domains in the context of a family-wide structural analysis

scientific article

Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms

scientific article published on 13 November 2006

High throughput crystallography at SGC Toronto: an overview.

scientific article

Histone recognition by human malignant brain tumor domains

scientific article

IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold

scientific article

In situ proteolysis for protein crystallization and structure determination

scientific article

Interferon-inducible protein 16: insight into the interaction with tumor suppressor p53

scientific article

Isolation, crystallization and preliminary X-ray analysis of a methanol-induced corrinoid protein from Moorella thermoacetica

scientific article

Life in the fast lane for protein crystallization and X-ray crystallography

scientific article

Mechanism of class 1 (glycosylhydrolase family 47) {alpha}-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control

scientific article published on 15 February 2005

Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway

scientific article published on 9 April 2018

New small molecule inhibitors of histone methyl transferase DOT1L with a nitrile as a non-traditional replacement for heavy halogen atoms

scientific article published on 21 July 2016

Nicotinamide riboside kinase structures reveal new pathways to NAD+

scientific article

Outcome of the First wwPDB/CCDC/D3R Ligand Validation Workshop

scientific article

Peptide recognition by heterochromatin protein 1 (HP1) chromoshadow domains revisited: Plasticity in the pseudosymmetric histone binding site of human HP1.

scientific article published on 21 February 2017

Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin  1

scientific article

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

scientific article

RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation

scientific article

Sequence-specific recognition of a PxLPxI/L motif by an ankyrin repeat tumbler lock

scientific article

Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation

scientific article

Structural Basis for Specific Binding of Human MPP8 Chromodomain to Histone H3 Methylated at Lysine 9

scientific article

Structural Insights into the Allosteric Effects of 4EBP1 on the Eukaryotic Translation Initiation Factor eIF4E ⬇️

scientific article published on December 9, 2011

Structural and Histone Binding Ability Characterizations of Human PWWP Domains

scientific article

Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases

scientific article

Structural and chemical profiling of the human cytosolic sulfotransferases

scientific article

Structural and functional analysis of the DOT1L-AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis

scientific article published on 21 March 2018

Structural and transcriptional analyses of a purine nucleotide-binding protein from Pyrococcus furiosus: a component of a novel, membrane-bound multiprotein complex unique to this hyperthermophilic archaeon

scientific article published on March 2007

Structural basis for a novel interaction between TXNIP and Vav2

scientific journal article

Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1

scientific article

Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain

scientific article

Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP

scientific article

Structural basis of Rnd1 binding to plexin Rho GTPase binding domains (RBDs)

scientific article

Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases

scientific article

Structural characterization of human cholesterol 7α-hydroxylase

scientific article

Structural genomics of Pyrococcus furiosus: X-ray crystallography reveals 3D domain swapping in rubrerythrin

scientific article

Structure and Function of a G-actin Sequestering Protein with a Vital Role in Malaria Oocyst Development inside the Mosquito Vector

scientific article

Structure and function of the intracellular region of the plexin-b1 transmembrane receptor

scientific article

Structure of mouse Golgi alpha-mannosidase IA reveals the molecular basis for substrate specificity among class 1 (family 47 glycosylhydrolase) alpha1,2-mannosidases

scientific article published on 21 April 2004

Structure of the conserved transcriptional repressor enhancer of rudimentary homolog

scientific article (publication date: 5 April 2005)

Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome

scientific article published on 28 July 2015

Structure of the hypothetical protein PF0899 fromPyrococcus furiosusat 1.85 Å resolution

scientific article

Structure-Based Design of a Covalent Inhibitor of the SET Domain-Containing Protein 8 (SETD8) Lysine Methyltransferase

scientific article

Structures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-stranded N 6 -Methyladenosine RNA Demethylation

scientific article

Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium

scientific article

Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development

scientific article

The high-throughput protein-to-structure pipeline at SECSG.

scientific article

The tuberous sclerosis complex subunit TBC1D7 is stabilized by Akt phosphorylation-mediated 14-3-3 binding

scientific article published in Journal of Biological Chemistry

The xenograft antigen bound to Griffonia simplicifolia lectin 1-B(4). X-ray crystal structure of the complex and molecular dynamics characterization of the binding site

scientific article

Three-dimensional structure of GlcNAcalpha1-4Gal releasing endo-beta-galactosidase from Clostridium perfringens

scientific article published in April 2005

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