"A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII
scientific article published on 18 December 2019
"Seriously Sweet": Acesulfame K Exhibits Selective Inhibition Using Alternative Binding Modes in Carbonic Anhydrase Isoforms
scientific article
(Hetero)aryl substituted thiazol-2,4-yl scaffold as human carbonic anhydrase I, II, VII and XIV activators
scientific article published on 01 December 2019
(In)organic anions as carbonic anhydrase inhibitors
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scientific article published on December 1, 2011
(R)-/(S)-10-camphorsulfonyl-substituted aromatic/heterocyclic sulfonamides selectively inhibit mitochondrial over cytosolic carbonic anhydrases
scientific article published on 18 January 2011
1,2,4-Triazole-based anticonvulsant agents with additional ROS scavenging activity are effective in a model of pharmacoresistant epilepsy
scientific article published on 01 December 2020
1,2,4-Trisubstituted imidazolinones with dual carbonic anhydrase and p38 mitogen-activated protein kinase inhibitory activity
scientific article published on 01 October 2018
1,2-Benzisothiazole Derivatives Bearing 4-, 5-, or 6-Alkyl/arylcarboxamide Moieties Inhibit Carbonic Anhydrase Isoform IX (CAIX) and Cell Proliferation under Hypoxic Conditions
scientific article published on 15 June 2016
1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors
scientific article published on 04 February 2020
1,3-Oxazole-based selective picomolar inhibitors of cytosolic human carbonic anhydrase II alleviate ocular hypertension in rabbits: Potency is supported by X-ray crystallography of two leads
scientific article published on 11 July 2017
2-Benzylpiperazine: A new scaffold for potent human carbonic anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering age
scientific article published on 3 April 2018
2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site
scientific article published on 23 June 2020
2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity
scientific article
3-Aminobenzenesulfonamides incorporating acylthiourea moieties selectively inhibit the tumor-associated carbonic anhydrase isoform IX over the off-target isoforms I, II and IV
scientific article published on 04 October 2018
3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights
scientific article published on 08 October 2019
3-Hydroxy-1H-quinazoline-2,4-dione as a New Scaffold To Develop Potent and Selective Inhibitors of the Tumor-Associated Carbonic Anhydrases IX and XII.
scientific article
3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies
scientific article published on 22 August 2020
3-phenyl-1H-indole-5-sulfonamides: structure-based drug design of a promising class of carbonic anhydrase inhibitors
scientific article published on January 2010
3D QSAR Selectivity Analyses of Carbonic Anhydrase Inhibitors: Insights for the Design of Isozyme Selective Inhibitors
scientific article published on 01 November 2006
3D QSAR studies, pharmacophore modeling, and virtual screening of diarylpyrazole-benzenesulfonamide derivatives as a template to obtain new inhibitors, using human carbonic anhydrase II as a model protein.
scientific article published in December 2017
3D-QSAR CoMFA studies on sulfonamide inhibitors of the Rv3588c β-carbonic anhydrase from Mycobacterium tuberculosis and design of not yet synthesized new molecules
scientific article published in July 2013
3H-1,2-benzoxathiepine 2,2-dioxides: a new class of isoform-selective carbonic anhydrase inhibitors.
scientific article published in December 2017
4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies
scientific article
4-Functionalized 1,3-diarylpyrazoles bearing 6-aminosulfonylbenzothiazole moiety as potent inhibitors of carbonic anhydrase isoforms hCA I, II, IX and XII
scientific article published on 22 October 2014
4-Functionalized 1,3-diarylpyrazoles bearing benzenesulfonamide moiety as selective potent inhibitors of the tumor associated carbonic anhydrase isoforms IX and XII.
scientific article
4-Hydroxy-3-nitro-5-ureido-benzenesulfonamides Selectively Target the Tumor-Associated Carbonic Anhydrase Isoforms IX and XII Showing Hypoxia-Enhanced Antiproliferative Profiles
scientific article published on 28 November 2018
4-Substituted Benzenesulfonamides Incorporating Bi/Tricyclic Moieties Act as Potent and Isoform-Selective Carbonic Anhydrase II/IX Inhibitors
scientific article published on 27 June 2018
4-Substituted benzenesulfonamides featuring cyclic imides moieties exhibit potent and isoform-selective carbonic anhydrase II/IX inhibition
scientific article published on 19 October 2018
5- and 6-Membered (thio)lactones are prodrug type carbonic anhydrase inhibitors
scientific article published on 11 November 2011
5-Aryl-1H-pyrazole-3-carboxylic acids as selective inhibitors of human carbonic anhydrases IX and XII
scientific article published on 04 June 2015
5-Arylisothiazol-3(2H)-one-1,(1)-(di)oxides: A new class of selective tumor-associated carbonic anhydrases (hCA IX and XII) inhibitors
scientific article published on 30 April 2019
5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: solution and X-ray crystallographic studies
scientific article
5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations
scientific article
6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA
scientific article published on 01 January 2015
6-Substituted sulfocoumarins are selective carbonic anhdydrase IX and XII inhibitors with significant cytotoxicity against colorectal cancer cells
scientific article
6-Triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrases IX and XII
scientific article published on 02 February 2014
7,8-disubstituted- but not 6,7-disubstituted coumarins selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II in the low nanomolar/subnanomolar range
scientific article published on 25 October 2010
7-Acylamino-3H-1,2-benzoxathiepine 2,2-dioxides as new isoform-selective carbonic anhydrase IX and XII inhibitors
scientific article published on 01 December 2020
7-Amino-3,4-dihydro-1H-quinolin-2-one, a compound similar to the substituted coumarins, inhibits α-carbonic anhydrases without hydrolysis of the lactam ring.
scientific article
7-Aryl-triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrase IX and XII
scientific article published on 18 December 2015
7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors.
scientific article published on 31 May 2013
9,10-Dibromo-N-aryl-9,10-dihydro-9,10-[3,4]epipyrroloanthracene-12,14-diones: Synthesis and Investigation of Their Effects on Carbonic Anhydrase Isozymes I, II, IX, and XII
scientific article published on 13 May 2016
A Class of Sulfonamides with Strong Inhibitory Action against the α-Carbonic Anhydrase from Trypanosoma cruzi
scientific article published on 10 July 2013
A Combined Crystallographic and Theoretical Study Explains the Capability of Carboxylic Acids to Adopt Multiple Binding Modes in the Active Site of Carbonic Anhydrases
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A Combined in Silico and Structural Study Opens New Perspectives on Aliphatic Sulfonamides, a Still Poorly Investigated Class of CA Inhibitors
A Highlight on the Inhibition of Fungal Carbonic Anhydrases as Drug Targets for the Antifungal Armamentarium
scientific article published in 2021
A Key Opinion Leader interview: insight into the research and career of Prof. Claudiu T Supuran
scientific article published on 10 March 2015
A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer's Disease
scientific article published on 24 September 2019
A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity
scientific article published on 09 November 2020
A Phase 1 Study of SLC-0111, a Novel Inhibitor of Carbonic Anhydrase IX, in Patients With Advanced Solid Tumors
scientific article published on 02 April 2020
A Small-Molecule Drug Conjugate for the Treatment of Carbonic Anhydrase IX Expressing Tumors
A class of 4-sulfamoylphenyl-ω-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects.
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A class of carbonic anhydrase I - selective activators.
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A class of carbonic anhydrase IX/XII - selective carboxylate inhibitors
scientific article published on 01 December 2020
A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects
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A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors
scientific article published on 27 July 2019
A deadly spillover: SARS-CoV-2 outbreak
scientific article published on 23 April 2020
A failed tentative to design a super carbonic anhydrase having the biochemical properties of the most thermostable CA (SspCA) and the fastest (SazCA) enzymes.
scientific article published on 16 February 2015
A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules
scientific article published on 28 May 2013
A magnificent enzyme superfamily: carbonic anhydrases, their purification and characterization.
scientific article published on 29 June 2015
A new affinity gel for the purification of α-carbonic anhdrases
scientific article published on 17 June 2014
A new approach to antiglaucoma drugs: carbonic anhydrase inhibitors with or without NO donating moieties. Mechanism of action and preliminary pharmacology
scientific article published on 04 August 2011
A new class of quinazoline-sulfonamides acting as efficient inhibitors against the α-carbonic anhydrase from Trypanosoma cruzi
scientific article published on 06 November 2014
A new coral carbonic anhydrase in Stylophora pistillata
scientific article published on 12 February 2011
A new procedure for the cloning, expression and purification of the β-carbonic anhydrase from the pathogenic yeast Malassezia globosa, an anti-dandruff drug target.
scientific article published on 2 November 2015
A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth
scientific article published on 30 December 2010
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells
scientific article published on 28 May 2019
A novel acidification mechanism for greatly enhanced oxygen supply to the fish retina
scientific article published on 25 August 2020
A novel class of carbonic anhydrase inhibitors: glycoconjugate benzene sulfonamides prepared by "click-tailing"
scientific article published on 01 November 2006
A novel library of saccharin and acesulfame derivatives as potent and selective inhibitors of carbonic anhydrase IX and XII isoforms.
scientific article published on 20 January 2016
A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction
scientific article published on 22 January 2019
A one-step procedure for immobilising the thermostable carbonic anhydrase (SspCA) on the surface membrane of Escherichia coli
scientific article published in December 2017
A perspective on quantitative structure-activity relationships and carbonic anhydrase inhibitors
scientific article published on February 2006
A physically interpretable quantum-theoretic QSAR for some carbonic anhydrase inhibitors with diverse aromatic rings, obtained by a new QSAR procedure
scientific article
A potentiated cooperation of carbonic anhydrase IX and histone deacetylase inhibitors against cancer
scientific article published on 01 December 2020
A prodrug approach toward cancer-related carbonic anhydrase inhibition.
scientific article
A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors
scientific article published on 01 December 2020
A substituted sulfonamide and its Co (II), Cu (II), and Zn (II) complexes as potential antifungal agents.
scientific article published on 27 May 2016
A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases
scientific article
Acetaldehyde-derived modifications on cytosolic human carbonic anhydrases
scientific article published on 16 June 2011
Acetazolamide for the treatment of idiopathic intracranial hypertension
scientific article published on 07 July 2015
Acetylcholinesterase and carbonic anhydrase inhibitory properties of novel urea and sulfamide derivatives incorporating dopaminergic 2-aminotetralin scaffolds
scientific article published on 02 April 2016
Acetylcholinesterase and carbonic anhydrase isoenzymes I and II inhibition profiles of taxifolin
scientific article published on 20 April 2015
Activation Effects of Carnosine- and Histidine-Containing Dipeptides on Human Carbonic Anhydrases: A Comprehensive Study
scientific article published on 04 March 2020
Activation Profile Analysis of CruCA4, an α-Carbonic Anhydrase Involved in Skeleton Formation of the Mediterranean Red Coral, Corallium rubrum.
scientific article published on 28 December 2017
Activation Studies of the β-Carbonic Anhydrase from the Pathogenic Protozoan with Amino Acids and Amines
scientific article published on 01 February 2019
Activation Studies of the γ-Carbonic Anhydrases from the Antarctic Marine Bacteria Pseudoalteromonas haloplanktis and Colwellia psychrerythraea with Amino Acids and Amines.
scientific article
Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators
scientific article published on 01 December 2021
Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivatives
scientific article published on 01 December 2019
Activation of α-, β-, γ- δ-, ζ- and η- class of carbonic anhydrases with amines and amino acids: a review
scientific article published on 01 December 2019
Activation of β- and γ-carbonic anhydrases from pathogenic bacteria with tripeptides.
scientific article published in December 2018
Activation studies of the α- and β-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae with amines and amino acids.
scientific article published in December 2018
Activation studies of the β-carbonic anhydrases from Escherichia coli with amino acids and amines
scientific article published on 01 December 2020
Activation studies of the β-carbonic anhydrases from Malassezia restricta with amines and amino acids
scientific article published on 01 December 2020
Activation studies with amines and amino acids of the α-carbonic anhydrase from the pathogenic protozoan Trypanosoma cruzi
scientific article published on 07 July 2018
Activation studies with amines and amino acids of the β-carbonic anhydrase encoded by the Rv3273 gene from the pathogenic bacterium Mycobacterium tuberculosis
scientific article published in December 2018
Activation studies with amines and amino acids of the β-carbonic anhydrase from the pathogenic protozoan Leishmania donovani chagasi.
scientific article published on 16 April 2018
Active Blood Acidification Greatly Enhances Oxygen Supply to the Teleost Retina
scientific article published in 2021
Active Components of Essential Oils as Anti-Obesity Potential Drugs Investigated by in Silico Techniques
scientific article published on 21 June 2016
Acyl selenoureido benzensulfonamides show potent inhibitory activity against carbonic anhydrases from the pathogenic bacterium Vibrio cholerae
scientific article published on 21 September 2017
Adrenergic agonists and antagonists as antiglaucoma agents: a literature and patent review (2013-2019)
scientific article published on 09 September 2019
Advances in microwave-assisted synthesis and the impact of novel drug discovery
scientific article published on 16 July 2018
Advances in new psychoactive substances identification: the U.R.I.To.N. Consortium.
scientific article published in December 2017
Advances in structure-based drug discovery of carbonic anhydrase inhibitors
scientific article
Advances in the Inhibitory and Structural Investigations on Carbonic Anhydrase Isozymes XIII and XV
Advances in the structural annotation of human carbonic anhydrases and impact on future drug discovery
scientific article published on 22 August 2019
Adverse cardiovascular effects of the coxibs
scientific article
Affinity of sulfamates and sulfamides to carbonic anhydrase II isoform: experimental and molecular modeling approaches
scientific article published in June 2010
Agents for the prevention and treatment of age-related macular degeneration and macular edema: a literature and patent review
scientific article published on 24 September 2019
Agents that target cysteine residues of biomolecules and their therapeutic potential
Amide derivatives of benzene-sulfonanilide, pharmaceutical composition thereof and method for cancer treatment using the same (US20120095092).
scientific article published on 31 July 2012
Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII.
scientific article
Amino Acids as Building Blocks for Carbonic Anhydrase Inhibitors
scientific article published on 24 May 2018
An AGT-based protein-tag system for the labelling and surface immobilization of enzymes on E. coli outer membrane
scientific article published on 01 December 2019
An Overview of the Bacterial Carbonic Anhydrases
scientific article published on 11 November 2017
An Overview of the Carbonic Anhydrases from Two Pathogens of the Oral Cavity: Streptococcus mutans and Porphyromonas gingivalis
scientific article published on 13 April 2016
An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C
scientific article
An Update on Natural Products with Carbonic Anhydrase Inhibitory Activity
scientific article published on 10 December 2015
An alternative purification method for human serum paraoxonase 1 and its interactions with sulfonamides
scientific article published on 11 October 2010
An efficient method for the synthesis of novel derivatives 4-{5-[4-(4-amino-5-mercapto-4H-[1,2,4]triazol-3-yl)-phenyl]-3-trifluoromethyl-pyrazol-1-yl}-benzenesulfonamide and their anti-inflammatory potential
scientific article published on 05 July 2019
An evaluation of cytosolic erythrocyte carbonic anhydrase and catalase in carcinoma patients: An elevation of carbonic anhydrase activity
scientific article published on 19 April 2006
An inhibitor-like binding mode of a carbonic anhydrase activator within the active site of isoform II
scientific article published on 14 October 2010
An overview of the alpha-, beta- and gamma-carbonic anhydrases from Bacteria: can bacterial carbonic anhydrases shed new light on evolution of bacteria?
scientific article published on 25 April 2014
An update in the development of HIV entry inhibitors
scientific article published on January 2007
An update on drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors
scientific article published on 21 March 2020
An α-carbonic anhydrase from the thermophilic bacterium Sulphurihydrogenibium azorense is the fastest enzyme known for the CO2 hydration reaction
scientific article published on 29 September 2012
Analysis of Human Carbonic Anhydrase II: Docking Reliability and Receptor-Based 3D-QSAR Study
article
Analysis of a shortened form of human carbonic anhydrase VII expressed in vitro compared to the full-length enzyme
scientific article published on 21 May 2010
Analysis of saponins and phenolic compounds as inhibitors of α-carbonic anhydrase isoenzymes
scientific article published on 03 February 2012
Anion Inhibition Profile of the β-Carbonic Anhydrase from the Opportunist Pathogenic Fungus Malassezia Restricta Involved in Dandruff and Seborrheic Dermatitis
scientific article published on 18 July 2019
Anion Inhibition Studies of the Beta-Carbonic Anhydrase from Escherichia coli
scientific article published on 31 May 2020
Anion Inhibition Studies of the β-Class Carbonic Anhydrase CAS3 from the Filamentous Ascomycete Sordaria macrospora
scientific article published on 05 March 2020
Anion and sulfonamide inhibition studies of an α-carbonic anhydrase from the Antarctic hemoglobinless fish Chionodraco hamatus
scientific article published on 26 October 2015
Anion inhibition profiles of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum
scientific article published on 18 July 2016
Anion inhibition profiles of the γ-carbonic anhydrase from the pathogenic bacterium Burkholderia pseudomallei responsible of melioidosis and highly drug resistant to common antibiotics.
scientific article
Anion inhibition profiles of α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae
scientific article published on 18 May 2016
Anion inhibition studies of a beta carbonic anhydrase from the malaria mosquito Anopheles gambiae.
scientific article published in December 2018
Anion inhibition studies of a β-carbonic anhydrase from Clostridium perfringens.
scientific article
Anion inhibition studies of an α-carbonic anhydrase from the living fossil Astrosclera willeyana.
scientific article published on 23 December 2011
Anion inhibition studies of an α-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1.
scientific article published on 9 July 2012
Anion inhibition studies of the Zn(II)-bound ι-carbonic anhydrase from the Gram-negative bacterium <i>Burkholderia territorii</i>
scientific article published on 01 December 2021
Anion inhibition studies of the dandruff-producing fungus Malassezia globosa β-carbonic anhydrase MgCA.
scientific article published on 3 October 2015
Anion inhibition studies of the fastest carbonic anhydrase (CA) known, the extremo-CA from the bacterium Sulfurihydrogenibium azorense
scientific article published on 27 September 2012
Anion inhibition studies of the α-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.
scientific article
Anion inhibition studies of the α-carbonic anhydrase from the protozoan pathogen Trypanosoma cruzi, the causative agent of Chagas disease
scientific article published on 6 June 2013
Anion inhibition studies of the β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae
scholarly article by Daniela Vullo published in March 2016
Anion inhibition studies of two new β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila
scientific article published on 08 January 2014
Anion inhibition studies of two α-carbonic anhydrases from Lotus japonicus, LjCAA1 and LjCAA2.
scientific article published on 8 April 2014
Anion inhibition study of the β-carbonic anhydrase (CahB1) from the cyanobacterium Coleofasciculus chthonoplastes (ex-Microcoleus chthonoplastes).
scientific article published on 29 January 2014
Anion inhibition study of the β-class carbonic anhydrase (PgiCAb) from the oral pathogen Porphyromonas gingivalis
scientific article published on 12 August 2014
Anion inhibitors of the β-carbonic anhydrase from the pathogenic bacterium responsible of tularemia, Francisella tularensis
scientific article published on 17 July 2017
Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer
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Anti-Helicobacter pylori activity of ethoxzolamide
scientific article published on 01 December 2019
Anti-breast cancer action of carbonic anhydrase IX inhibitor 4-[4-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-benzylidene-hydrazinocarbonyl]-benzenesulfonamide (BSM-0004): <i>in vitro</i> and <i>in vivo</i> studies
scientific article published on 01 December 2021
Anti-infective carbonic anhydrase inhibitors: a patent and literature review
scientific article published on 14 March 2013
Antibacterial Co(II) and Ni(II) Complexes of N-(2-Furanylmethylene)-2-Aminothiadiazole and Role of SO(4), NO(3), C(2)O(4) and CH(3)CO(2) anions on Biological Properties
scientific article published in January 2002
Antibacterial Co(II), Cu(II), Ni(II) and Zn(II) complexes of thiadiazole derived furanyl, thiophenyl and pyrrolyl Schiff bases
scientific article published in April 2002
Antibacterial Role of SO(4), NO(3), C(2)O(4) and CH(3)CO(2) Anions on Cu(II) and Zn(II) Complexes of a Thiadiazole-derived Pyrrolyl Schiff Base
scientific article published on January 2002
Antibacterial Schiff bases of oxalyl-hydrazine/diamide incorporating pyrrolyl and salicylyl moieties and of their zinc(II) complexes
scientific article published in February 2002
Antibacterial activity of ethoxzolamide against Helicobacter pylori strains SS1 and 26695
scientific article published on 15 April 2020
Antibacterial and antifugal mono- and di-substituted symmetrical and unsymmetrical triazine-derived Schiff-bases and their transition metal complexes
scientific article published in April 2004
Antibacterial carbonic anhydrase inhibitors: an update on the recent literature
scientific article published on 17 August 2020
Antibacterial cobalt (II), copper (II), nickel (II) and zinc (II) complexes of mercaptothiadiazole--derived furanyl, thienyl, pyrrolyl, salicylyl and pyridinyl Schiff bases
scientific article published in April 2006
Antibacterial cobalt(II), nickel(II) and zinc(II) complexes of nicotinic acid-derived Schiff-bases
scientific article published in April 2002
Antibacterial, antifungal and cytotoxic properties of novel N-substituted sulfonamides from 4-hydroxycoumarin.
scientific article published in December 2006
Antibacterial, antifungal and cytotoxic properties of some sulfonamide-derived chromones
scientific article published in April 2006
Anticancer and antiviral sulfonamides
scientific article
Anticancer carbonic anhydrase inhibitors: a patent review (2008 - 2013).
scientific article published on 15 May 2013
Anticancer effects of new dibenzenesulfonamides by inducing apoptosis and autophagy pathways and their carbonic anhydrase inhibitory effects on hCA I, hCA II, hCA IX, hCA XII isoenzymes
scientific article published on 30 March 2018
Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography
scientific article
Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIV
scientific article
Anticonvulsant sulfonamides/sulfamates/sulfamides with carbonic anhydrase inhibitory activity: drug design and mechanism of action
scientific article published on January 2008
Antifungal Activity of Ag(I) and Zn(II) Complexes of Sulfacetamide Derivatives
scientific article
Antifungal cobalt(II), copper(II), nickel(II) and zinc(II) complexes of furanyl-,thiophenyl-, pyrrolyl-, salicylyl- and pyridyl-derived cephalexins
scientific article
Antiglaucoma Carbonic Anhydrase Inhibitors as Ophthalomologic Drugs
Antiglaucoma carbonic anhydrase inhibitors: a patent review
scientific article published on 30 April 2013
Antileishmanial activity of sulphonamide nanoemulsions targeting the β-carbonic anhydrase from Leishmania species.
scientific article published in December 2018
Antimetastatic effect of sulfamate carbonic anhydrase IX inhibitors in breast carcinoma xenografts.
scientific article published on 5 June 2012
Antiobesity carbonic anhydrase inhibitors
scientific article published on January 2007
Antiobesity carbonic anhydrase inhibitors: a literature and patent review
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scientific article published on April 22, 2013
Antiviral sulfonamide derivatives
scientific article published on February 2004
Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors
scientific article published on 14 March 2020
Application of hydrazino and hydrazido linkers to connect benzenesulfonamides with hydrophilic/phobic tails for targeting the middle region of human carbonic anhydrases active site: Selective inhibitors of hCA IX
scientific article published on 28 June 2019
Applications of carbonic anhydrase inhibitors and activators in therapy
Applications of carbonic anhydrases inhibitors in renal and central nervous system diseases
scientific article published on 10 September 2018
Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani
scientific article published on 01 December 2019
Are Carbonic Anhydrases Suitable Targets to Fight Protozoan Parasitic Diseases?
scientific article published on 26 March 2018
Are carbonic anhydrase inhibitors suitable for obtaining antiobesity drugs?
scientific article published on January 2008
Aryl derivatives of 3H-1,2-benzoxathiepine 2,2-dioxide as carbonic anhydrase inhibitors
scientific article published on 01 December 2020
Aryl-4,5-dihydro-1H-pyrazole-1-carboxamide Derivatives Bearing a Sulfonamide Moiety Show Single-digit Nanomolar-to-Subnanomolar Inhibition Constants against the Tumor-associated Human Carbonic Anhydrases IX and XII
scientific article published on 09 April 2020
Arylamino bisphosphonates: potent and selective inhibitors of the tumor-associated carbonic anhydrase XII
scientific article published on 12 March 2014
Ascaris lumbricoides β carbonic anhydrase: a potential target enzyme for treatment of ascariasis.
scientific article published on 18 September 2015
Assessment of the antiproliferative and apoptotic roles of sulfonamide carbonic anhydrase IX inhibitors in HeLa cancer cell line
scientific article published on 01 December 2019
Attachment of carbohydrates to methoxyaryl moieties leads to highly selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII.
scientific article published on 7 August 2014
Azidothymidine (AZT) "clicked" into 1,2,3-Triazoles: First Report on Carbonic Anhydrase-Telomerase Dual Hybrid Inhibitors
scientific article published on 28 May 2020
Bacterial Carbonic Anhydrases as Drug Targets: Toward Novel Antibiotics?
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scientific article published on July 5, 2011
Bacterial protease inhibitors
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Bacterial proteases: current therapeutic use and future prospects for the development of new antibiotics
article
Bacterial ι-carbonic anhydrase: a new active class of carbonic anhydrase identified in the genome of the Gram-negative bacterium Burkholderia territorii
scientific article published on 01 December 2020
Bacterial, fungal and protozoan carbonic anhydrases as drug targets.
scientific article published on August 2015
Benzamide-4-Sulfonamides Are Effective Human Carbonic Anhydrase I, II, VII, and IX Inhibitors.
scientific article published in June 2018
Benzenesulfonamide bearing 1,2,4-triazole scaffolds as potent inhibitors of tumor associated carbonic anhydrase isoforms hCA IX and hCA XII
scientific article published on 07 February 2014
Benzenesulfonamide bearing imidazothiadiazole and thiazolotriazole scaffolds as potent tumor associated human carbonic anhydrase IX and XII inhibitors.
scientific article published on 29 December 2016
Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations
scientific article published on 21 November 2016
Benzenesulfonamides incorporating bulky aromatic/heterocyclic tails with potent carbonic anhydrase inhibitory activity
scientific article published on 23 November 2015
Benzenesulfonamides incorporating nitrogenous bases show effective inhibition of β-carbonic anhydrases from the pathogenic fungi Cryptococcus neoformans, Candida glabrata and Malassezia globosa
scientific article published on 19 January 2019
Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects
scientific article published on 21 May 2019
Benzimidazole derivatives as potent and isoform selective tumor-associated carbonic anhydrase IX/XII inhibitors
scientific article published on 28 December 2019
Benzofuran-Based Carboxylic Acids as Carbonic Anhydrase Inhibitors and Antiproliferative Agents against Breast Cancer
scientific article published on 18 March 2020
Benzolamide is not a membrane-impermeant carbonic anhydrase inhibitor
scientific article published in June 2004
Benzothiadiazinone-1,1-Dioxide Carbonic Anhydrase Inhibitors Suppress the Growth of Drug-Resistant Mycobacterium tuberculosis Strains
scientific article published in 2024
Benzothiazole derivatives as anticancer agents
scientific article published on 01 December 2020
Benzoxaborole as a new chemotype for carbonic anhydrase inhibition
scientific article
Benzoxaborole compounds for therapeutic uses: a patent review (2010- 2018)
scientific article published on 11 May 2018
Benzoxaboroles as Efficient Inhibitors of the β-Carbonic Anhydrases from Pathogenic Fungi: Activity and Modeling Study
scientific article published on 20 October 2017
Benzoxaboroles: New Potent Inhibitors of the Carbonic Anhydrases of the Pathogenic Bacterium Vibrio cholerae
scientific article published on 09 September 2020
Benzoxepinones: A new isoform-selective class of tumor associated carbonic anhydrase inhibitors
scientific article published on 14 April 2020
Benzyl alcohol inhibits carbonic anhydrases by anchoring to the zinc coordinated water molecule
scientific article published in 2021
Benzylaminoethylureido-tailed benzenesulfonamides show potent inhibitory action against bacterial carbonic anhydrases
scientific article published on 23 September 2020
Benzylaminoethyureido-Tailed Benzenesulfonamides: Design, Synthesis, Kinetic and X-ray Investigations on Human Carbonic Anhydrases
scientific article published on 07 April 2020
Bidentate Zinc Chelators for α-Carbonic Anhydrases that Produce a Trigonal Bipyramidal Coordination Geometry
scientific article
Binding of transition metal ions [cobalt, copper, nickel and zinc] with furanyl-, thiophenyl-, pyrrolyl-, salicylyl- and pyridyl-derived cephalexins as potent antibacterial agents
scientific article
Bioactive Natural Product and Superacid Chemistry for Lead Compound Identification: A Case Study of Selective hCA III and L-Type Ca2+ Current Inhibitors for Hypotensive Agent Discovery.
scientific article published on 31 May 2017
Bioactive isoflavones from Pueraria lobata root and starch: Different extraction techniques and carbonic anhydrase inhibition
scientific article published on 12 August 2017
Biochemical and Structural Insights into Carbonic Anhydrase XII/Fab6A10 Complex
scientific article published on 01 November 2019
Biochemical and structural characterisation of a protozoan beta-carbonic anhydrase from Trichomonas vaginalis
scientific article published on 01 December 2020
Biochemical and structural characterization of beta-carbonic anhydrase from the parasite Trichomonas vaginalis
scientific article published on 15 October 2021
Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes.
scientific article
Biochemical characterization of recombinant β-carbonic anhydrase (PgiCAb) identified in the genome of the oral pathogenic bacterium Porphyromonas gingivalis.
scientific article published on 17 July 2014
Biochemical characterization of the chloroplastic β-carbonic anhydrase from Flaveria bidentis (L.) "Kuntze".
scientific article published on 29 July 2013
Biochemical characterization of the native α-carbonic anhydrase purified from the mantle of the Mediterranean mussel, Mytilus galloprovincialis
scientific article published in December 2017
Biochemical characterization of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis, PgiCA.
scientific article published on 5 August 2013
Biochemical characterization of the δ-carbonic anhydrase from the marine diatom Thalassiosira weissflogii, TweCA
scientific article published on 24 January 2014
Biochemical properties of a new α-carbonic anhydrase from the human pathogenic bacterium, Vibrio cholerae
scientific article published on 16 January 2013
Biochemical, biophysical and molecular dynamics studies on the proteoglycan-like domain of carbonic anhydrase IX.
scientific article published on 21 March 2018
Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis
scientific article published on 15 November 2019
Biomedical applications of prokaryotic carbonic anhydrases
scientific article published on 16 July 2018
Biomimetic CO2 capture using a highly thermostable bacterial α-carbonic anhydrase immobilized on a polyurethane foam
scientific article published on 15 February 2013
Bioorganometallic derivatives of 4-hydrazino-benzenesulphonamide as carbonic anhydrase inhibitors: synthesis, characterisation and biological evaluation
scientific article published on 01 December 2020
Bis-benzoxaboroles: Design, Synthesis, and Biological Evaluation as Carbonic Anhydrase Inhibitors
scientific article published on 11 July 2019
Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival
scientific article published in Scientific Reports
Bortezomib inhibits bacterial and fungal β-carbonic anhydrases.
scientific article published on 18 July 2016
Bortezomib inhibits mammalian carbonic anhydrases
scientific article
Brucella carbonic anhydrases: new targets for designing anti-infective agents
scientific article
Burkholderia pseudomallei γ-carbonic anhydrase is strongly activated by amino acids and amines
scientific article published on 12 November 2016
C-glycosides incorporating the 6-methoxy-2-naphthyl moiety are selective inhibitors of fungal and bacterial carbonic anhydrases
scientific article published on 07 October 2014
CA IX stratification based on cancer treatment: a patent evaluation of US2016/0002350
scientific article published on 07 September 2016
CAIX furthers tumour progression in the hypoxic tumour microenvironment of esophageal carcinoma and is a possible therapeutic target.
scientific article published in December 2018
CDCA1 From Thalassiosira weissflogii as Representative Member of ζ-Class CAs: General Features and Biotechnological Applications
CO2 Permeability of Rat Hepatocytes and Relation of CO2 Permeability to CO2 Production
scientific article published on 16 April 2018
CO2 and HCO3- Permeability of the Rat Liver Mitochondrial Membrane.
scientific article published on 24 October 2016
CO2 permeability of cell membranes is regulated by membrane cholesterol and protein gas channels
scientific article published on 10 September 2012
COX-2 selective inhibitors, carbonic anhydrase inhibition and anticancer properties of sulfonamides belonging to this class of pharmacological agents
scientific article
Calixarenes Incorporating Sulfonamide Moieties: Versatile Ligands for Carbonic Anhydrases Inhibition
scientific article published in 2021
Cancer-associated, hypoxia-inducible carbonic anhydrase IX facilitates CO2 diffusion
scientific article
Carbamoylphosphonates control tumor cell proliferation and dissemination by simultaneously inhibiting carbonic anhydrase IX and matrix metalloproteinase-2. Toward nontoxic chemotherapy targeting tumor microenvironment
scientific article published on 28 August 2012
Carbamoylphosphonates inhibit autotaxin and metastasis formation in vivo
scientific article published on 11 February 2015
Carbon- versus sulphur-based zinc binding groups for carbonic anhydrase inhibitors?
scientific article published in December 2018
Carbonic Anhydrase Activators: Gold Nanoparticles Coated with Derivatized Histamine, Histidine, and Carnosine Show Enhanced Activatory Effects on Several Mammalian Isoforms
scientific article published on 03 February 2011
Carbonic Anhydrase Activators: High Affinity Isozymes I, II, and IV Activators, Incorporating a β-Alanyl-histidine Scaffold
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scientific article published on January 17, 2002
Carbonic Anhydrase Glycoinhibitors belonging to the Aminoxysulfonamide Series.
scientific article published on 2 June 2015
Carbonic Anhydrase II as Target for Drug Design
Carbonic Anhydrase Inhibition and the Management of Hypoxic Tumors
scientific article published on 16 September 2017
Carbonic Anhydrase Inhibition with Benzenesulfonamides and Tetrafluorobenzenesulfonamides Obtained via Click Chemistry
scientific article published on 7 June 2014
Carbonic Anhydrase Inhibition/Activation: Trip of a Scientist Around the World in the Search of Novel Chemotypes and Drug Targets
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scientific article published on January 1, 2010
Carbonic Anhydrase Inhibitor Coated Gold Nanoparticles Selectively Inhibit the Tumor-Associated Isoform IX over the Cytosolic Isozymes I and II
scientific article published on 01 December 2008
Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment
scientific article published on 14 October 2020
Carbonic Anhydrase Inhibitors and Activators for Novel Therapeutic Applications
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scientific article published on July 1, 2011
Carbonic Anhydrase Inhibitors as Novel Drugs against Mycobacterial β-Carbonic Anhydrases: An Update on and Studies
scientific article
Carbonic Anhydrase Inhibitors of Different Structures Dilate Pre-Contracted Porcine Retinal Arteries
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scientific article published on 22 January 2019
Carbonic Anhydrase Inhibitors: Clash with Ala65 as a Means for Designing Inhibitors with Low Affinity for the Ubiquitous Isozyme II, Exemplified by the Crystal Structure of the Topiramate Sulfamide Analogue†
scientific article published on 01 November 2006
Carbonic Anhydrase Inhibitors: Hypoxia-Activatable Sulfonamides Incorporating Disulfide Bonds that Target the Tumor-Associated Isoform IX†
scientific article published on 01 September 2006
Carbonic Anhydrase Inhibitors: Inhibition of Isozymes I, II And IV with Heterocyclic Mercaptans, Sulfenamides, Sulfonamides and their Metal Complexes
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scientific article published on June 1, 1998
Carbonic Anhydrase Inhibitors: Synthesis and Inhibition of Cytosolic/Membrane-Associated Carbonic Anhydrase Isozymes I, II, and IX with Sulfonamides Incorporating Hydrazino Moieties
scientific article published on 01 March 2005
Carbonic Anhydrase Inhibitors: X-ray and Molecular Modeling Study for the Interaction of a Fluorescent Antitumor Sulfonamide with Isozyme II and IX
article
Carbonic Anhydrase Protects Fatty Liver Grafts against Ischemic Reperfusion Damage
scientific article published on 30 July 2015
Carbonic Anhydrase VII
Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma
scientific article published on 10 April 2019
Carbonic Anhydrase from Porphyromonas Gingivalis as a Drug Target.
scientific article
Carbonic Anhydrase inhibitors bearing organotelluride moieties as novel agents for antitumor therapy
scientific article published in 2022
Carbonic Anhydrases and Metabolism
scientific article published on 21 March 2018
Carbonic Anhydrases: An Overview
article published in 2015
Carbonic anhydrase I and II activation with mono- and dihalogenated histamine derivatives
scientific article published on 22 June 2011
Carbonic anhydrase I, II, IV and IX inhibition with a series of 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives.
scientific article published in December 2017
Carbonic anhydrase II-induced selection of inhibitors from a dynamic combinatorial library of Schiff's bases
scientific article published on 17 September 2009
Carbonic anhydrase III: a neglected isozyme is stepping into the limelight
scientific article published on 18 July 2012
Carbonic anhydrase IX as a novel candidate in liquid biopsy
scientific article published on 01 December 2020
Carbonic anhydrase IX correlates with survival and is a potential therapeutic target for neuroblastoma
scientific article published on 17 April 2015
Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells
scientific article published on 08 May 2013
Carbonic anhydrase IX inhibition affects viability of cancer cells adapted to extracellular acidosis
scientific article published on 19 September 2017
Carbonic anhydrase IX inhibition is an effective strategy for osteosarcoma treatment
scientific article published on 10 September 2015
Carbonic anhydrase IX inhibitors in cancer therapy: an update
scientific article
Carbonic anhydrase IX: Biochemical and crystallographic characterization of a novel antitumor target
scientific article published on 11 August 2009
Carbonic anhydrase IX: a new druggable target for the design of antitumor agents.
scientific article published on May 2008
Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors
scientific article published on 05 January 2012
Carbonic anhydrase activation and the drug design
scientific article published on January 2008
Carbonic anhydrase activation enhances object recognition memory in mice through phosphorylation of the extracellular signal-regulated kinase in the cortex and the hippocampus.
scientific article published on 9 March 2017
Carbonic anhydrase activators
scientific article published on 26 February 2018
Carbonic anhydrase activators
Carbonic anhydrase activators. Activation of isoforms I, II, IV, VA, VII, and XIV with L- and D-phenylalanine and crystallographic analysis of their adducts with isozyme II: stereospecific recognition within the active site of an enzyme and its cons
scientific article
Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII, and XIV with l- and d-histidine and crystallographic analysis of their adducts with isoform II: engineering proton-transfer processes within the active site of an enzyme
scientific article published in September 2006
Carbonic anhydrase activators. Activation of the membrane-associated isoform XV with amino acids and amines.
scientific article published on 12 May 2009
Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines.
scientific article published on 4 February 2010
Carbonic anhydrase activators. The selective serotonin reuptake inhibitors fluoxetine, sertraline and citalopram are strong activators of isozymes I and II.
scientific article published in August 2003
Carbonic anhydrase activators: Activation of isozyme XIII with amino acids and amines
scientific article published on 30 May 2006
Carbonic anhydrase activators: Activation of the beta-carbonic anhydrase from the pathogenic yeast Candida glabrata with amines and amino acids
scientific article published on 20 January 2010
Carbonic anhydrase activators: Activation of the human cytosolic isozyme III and membrane-associated isoform IV with amino acids and amines
scientific article published on 28 June 2008
Carbonic anhydrase activators: Activation of the β-carbonic anhydrase from Malassezia globosa with amines and amino acids
scientific article published on 29 January 2016
Carbonic anhydrase activators: The first X-ray crystallographic study of an adduct of isoform I
scientific article published on 25 July 2006
Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with L-histidine as a platform for the design of stronger activators
scientific article
Carbonic anhydrase activators: activation of human isozymes I, II and IX with phenylsulfonylhydrazido l-histidine derivatives.
scientific article
Carbonic anhydrase activators: activation of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases with amino acids and amines
scientific article
Carbonic anhydrase activators: activation of the beta-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids
scientific article published on 5 February 2009
Carbonic anhydrase activators: activation of the beta-carbonic anhydrases from the pathogenic fungi Candida albicans and Cryptococcus neoformans with amines and amino acids.
scientific article published on 4 January 2010
Carbonic anhydrase activators: activation of the human isoforms VII (cytosolic) and XIV (transmembrane) with amino acids and amines
scientific article
Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines
scientific article
Carbonic anhydrase activators: an activation study of the human mitochondrial isoforms VA and VB with amino acids and amines
scientific article
Carbonic anhydrase activators: design of high affinity isozymes I, II, and IV activators, incorporating tri-/tetrasubstituted-pyridinium-azole moieties
scientific article published in January 2002
Carbonic anhydrase activators: human isozyme II is strongly activated by oligopeptides incorporating the carboxyterminal sequence of the bicarbonate anion exchanger AE1.
scientific article
Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV
scientific article
Carbonic anhydrase activators: l-Adrenaline plugs the active site entrance of isozyme II, activating better isoforms I, IV, VA, VII, and XIV
scientific article published on 15 November 2006
Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines
scientific article published on 6 March 2007
Carbonic anhydrase and acetylcholinesterase inhibitory effects of carbamates and sulfamoylcarbamates
scientific article published on 25 June 2014
Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates
scientific article published in 2007
Carbonic anhydrase binding site parameterization in OPLS-AA force field
scientific article published on 02 November 2012
Carbonic anhydrase from Apis mellifera: purification and inhibition by pesticides.
scientific article published in December 2017
Carbonic anhydrase in the scleractinian coral Stylophora pistillata: characterization, localization, and role in biomineralization
scientific article
Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol.
scientific article published on 5 February 2016
Carbonic anhydrase inhibition and the management of glaucoma: a literature and patent review 2013-2019
scientific article published on 15 October 2019
Carbonic anhydrase inhibition and the management of neuropathic pain
scientific article published on 21 May 2016
Carbonic anhydrase inhibition for the management of cerebral ischemia: in vivo evaluation of sulfonamide and coumarin inhibitors
scientific article published on 26 November 2015
Carbonic anhydrase inhibition with a series of novel benzenesulfonamide-triazole conjugates
scientific article published on 01 December 2018
Carbonic anhydrase inhibition with natural products: novel chemotypes and inhibition mechanisms
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scientific article published on August 28, 2010
Carbonic anhydrase inhibition: insight into non-COX-2 pharmacological effect of some coxibs
scientific article published on January 2008
Carbonic anhydrase inhibitors
scientific article (publication date: March 2003)
Carbonic anhydrase inhibitors
scientific article published in June 2010
Carbonic anhydrase inhibitors - Part 49: Synthesis of substituted ureido and thioureido derivatives of aromatic/heterocyclic sulfonamides with increased affinities for isozyme I
Carbonic anhydrase inhibitors and activators and their use in therapy
Carbonic anhydrase inhibitors and their potential in a range of therapeutic areas
scientific article published on 19 September 2018
Carbonic anhydrase inhibitors as anticonvulsant agents
scientific article published on January 2007
Carbonic anhydrase inhibitors as antitumor/antimetastatic agents: a patent review (2008-2018)
scientific article published on 09 August 2018
Carbonic anhydrase inhibitors as emerging agents for the treatment and imaging of hypoxic tumors
scientific article published on 22 November 2018
Carbonic anhydrase inhibitors as emerging drugs for the treatment of obesity
scientific article published on 01 June 2008
Carbonic anhydrase inhibitors as emerging drugs for the treatment of obesity
scientific article published on 16 February 2012
Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells
scientific article published on 07 August 2019
Carbonic anhydrase inhibitors developed through 'click tailing'.
scientific article published on January 2010
Carbonic anhydrase inhibitors drug design
scientific article published on January 2014
Carbonic anhydrase inhibitors that directly inhibit anion transport by the human Cl-/HCO3- exchanger, AE1.
scientific article
Carbonic anhydrase inhibitors with dual-tail moieties to match the hydrophobic and hydrophilic halves of the carbonic anhydrase active site
scientific article
Carbonic anhydrase inhibitors with strong topical antiglaucoma properties incorporating a 4-(2-aminopyrimidin-4-yl-amino)-benzenesulfonamide scaffold
scientific article published in February 2002
Carbonic anhydrase inhibitors — Part 29 1: Interaction of isozymes I, II and IV with benzolamide-like derivatives
Carbonic anhydrase inhibitors — Part 52. Metal complexes of heterocyclic sulfonamides: A new class of strong topical intraocular pressure-lowering agents in rabbits
Carbonic anhydrase inhibitors — Part 53. Synthesis of substituted-pyridinium derivatives of aromatic sulfonamides: The first non-polymeric membrane-impermeable inhibitors with selectivity for isozyme IV
article by Claudiu T. Supuran et al published July 1998 in European Journal of Medicinal Chemistry
Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties.
scientific article published in March 2002
Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I-XV.
scientific article published on 13 July 2010
Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB.
scientific article
Carbonic anhydrase inhibitors. Benzenesulfonamides incorporating cyanoacrylamide moieties strongly inhibit Saccharomyces cerevisiae β-carbonic anhydrase
scientific article published on 21 April 2013
Carbonic anhydrase inhibitors. Biphenylsulfonamides with inhibitory action towards the transmembrane, tumor-associated isozymes IX possess cytotoxic activity against human colon, lung and breast cancer cell lines
scientific article published on 20 October 2008
Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c.
scientific article published on 7 October 2009
Carbonic anhydrase inhibitors. Cloning, characterization and inhibition studies of the cytosolic isozyme III with anions
scientific article published on 20 October 2008
Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis
scientific journal article
Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors
scientific article
Carbonic anhydrase inhibitors. Comparison of chlorthalidone and indapamide X-ray crystal structures in adducts with isozyme II: when three water molecules and the keto-enol tautomerism make the difference
scientific article
Carbonic anhydrase inhibitors. Comparison of chlorthalidone, indapamide, trichloromethiazide, and furosemide X-ray crystal structures in adducts with isozyme II, when several water molecules make the difference
scientific article
Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors
scientific article published in January 2007
Carbonic anhydrase inhibitors. Design of anticonvulsant sulfonamides incorporating indane moieties
scientific article published in December 2004
Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors.
scientific article published on July 2005
Carbonic anhydrase inhibitors. Design of selective, membrane-impermeant inhibitors targeting the human tumor-associated isozyme IX.
scientific article published in April 2004
Carbonic anhydrase inhibitors. Diazenylbenzenesulfonamides are potent and selective inhibitors of the tumor-associated isozymes IX and XII over the cytosolic isoforms I and II.
scientific article published on 6 September 2009
Carbonic anhydrase inhibitors. Identification of selective inhibitors of the human mitochondrial isozymes VA and VB over the cytosolic isozymes I and II from a natural product-based phenolic library
scientific article
Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides
scientific article
Carbonic anhydrase inhibitors. Inhibition of Plasmodium falciparum carbonic anhydrase with aromatic sulfonamides: towards antimalarials with a novel mechanism of action?
scientific article published in January 2005
Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I and II, and extracellular isoforms IV, IX, and XII with sulfamides incorporating sugar moieties
scientific article published on 13 July 2007
Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions
scientific article published on 26 February 2009
Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design.
scientific article
Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, cancer-associated isozyme IX with lipophilic sulfonamides
scientific article published in August 2003
Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, tumor-associated isozyme IX with sulfamates including EMATE also acting as steroid sulfatase inhibitors
scientific article published in May 2003
Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff's bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes
scientific article published in June 2005
Carbonic anhydrase inhibitors. Inhibition of human cytosolic isoforms I and II with (reduced) Schiff's bases incorporating sulfonamide, carboxylate and carboxymethyl moieties.
scientific article
Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols.
scientific article published on 4 February 2009
Carbonic anhydrase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozymes I and II with some 1,3,4-oxadiazole-thiols
Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX, and XIV with sulfonamides incorporating fructopyranose–thioureido tails
scientific article published on 12 March 2007
Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V and IX with complex fluorides, chlorides and cyanides
scientific article
Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate
scientific article published in February 2005
Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids
scientific article published on 6 February 2010
Carbonic anhydrase inhibitors. Inhibition of mitochondrial isozyme V with aromatic and heterocyclic sulfonamides.
scientific article published in February 2004
Carbonic anhydrase inhibitors. Inhibition of red blood cell ostrich (Struthio camelus) carbonic anhydrase with a series of aromatic and heterocyclic sulfonamides
scientific article
Carbonic anhydrase inhibitors. Inhibition of the Rv1284 and Rv3273 beta-carbonic anhydrases from Mycobacterium tuberculosis with diazenylbenzenesulfonamides.
scientific article published on 22 July 2009
Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the methanoarchaeon Methanobacterium thermoautotrophicum (Cab) with anions
scientific article published in September 2004
Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the pathogenic yeast Candida glabrata with anions.
scientific article published on 16 June 2009
Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with anions
scientific article
Carbonic anhydrase inhibitors. Inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with aliphatic and aromatic carboxylates
scientific article
Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II and IX with some 1,3,4-oxadiazole- and 1,2,4-triazole-thiols
scientific article published in January 2008
Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols
scientific article
Carbonic anhydrase inhibitors. Inhibition of the cytosolic human isozymes I and II, and the transmembrane, tumor-associated isozymes IX and XII with substituted aromatic sulfonamides activatable in hypoxic tumors
scientific article published on 30 June 2006
Carbonic anhydrase inhibitors. Inhibition of the fungal β-carbonic anhydrases from Candida albicans and Cryptococcus neoformans with boronic acids
scientific article published on 05 April 2009
Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isoforms I and II and transmembrane, tumor-associated isoforms IX and XII with boronic acids
scientific article published on 5 April 2009
Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides
scientific article
Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides.
scientific article
Carbonic anhydrase inhibitors. Inhibition of the newly isolated murine isozyme XIII with anions
scientific article published in November 2004
Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides
scientific article published in December 2004
Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?
scientific article
Carbonic anhydrase inhibitors. Inhibition of the zinc and cobalt gamma-class enzyme from the archaeon Methanosarcina thermophila with anions
scientific article
Carbonic anhydrase inhibitors. Inhibition of the zinc and cobalt γ-class enzyme from the archaeon Methanosarcina thermophila with anions
scholarly article by Alessio Innocenti et al published June 2004 in Bioorganic & Medicinal Chemistry Letters
Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with branched aliphatic/aromatic carboxylates and their derivatives
scientific article published on 17 February 2011
Carbonic anhydrase inhibitors. Inhibition of transmembrane isoforms IX, XII, and XIV with less investigated anions including trithiocarbonate and dithiocarbamate
scientific article published on 21 January 2010
Carbonic anhydrase inhibitors. Inhibition of transmembrane isozymes XII (cancer-associated) and XIV with anions
scientific article published on 13 January 2007
Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives
scientific article published in May 2003
Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides.
scientific article
Carbonic anhydrase inhibitors. Inhibition studies of the human secretory isoform VI with anions
scientific article published on 15 November 2006
Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata.
scientific article
Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies
scientific article
Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies
scientific article
Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adduct
scientific article
Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with organic phosphates and phosphonates
scientific article
Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with phosphates, carbamoyl phosphate, and the phosphonate antiviral drug foscarnet
scientific article published in December 2004
Carbonic anhydrase inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: kinetic and X-ray crystallographic studies
scientific article
Carbonic anhydrase inhibitors. Interaction of the antitumor sulfamate EMD 486019 with twelve mammalian carbonic anhydrase isoforms: Kinetic and X-ray crystallographic studies
scientific article
Carbonic anhydrase inhibitors. N-Cyanomethylsulfonamides—a new zinc binding group in the design of inhibitors targeting cytosolic and membrane-anchored isoforms
Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX.
scientific article published in January 2005
Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors
scientific article published on 3 May 2009
Carbonic anhydrase inhibitors. Phenols incorporating 2- or 3-pyridyl-ethenylcarbonyl and tertiary amine moieties strongly inhibit Saccharomyces cerevisiae β-carbonic anhydrase.
scientific article published in July 2013
Carbonic anhydrase inhibitors. Preparation of potent sulfonamides inhibitors incorporating bile acid tails
scientific article published in June 2002
Carbonic anhydrase inhibitors. Regioselective synthesis of novel 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII.
scientific article published on 12 May 2010
Carbonic anhydrase inhibitors. Regioselective synthesis of novel series 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII
scientific article published on 11 August 2012
Carbonic anhydrase inhibitors. Selective inhibition of human tumor-associated isozymes IX and XII and cytosolic isozymes I and II with some substituted-2-mercapto-benzenesulfonamides
Carbonic anhydrase inhibitors. Sulfonamide diuretics revisited--old leads for new applications?
scientific article published on 29 May 2008
Carbonic anhydrase inhibitors. Synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with boron-containing sulfonamides, sulfamides, and sulfamates: toward agents for boron neutron capture therapy of [...]
scientific article published in July 2005
Carbonic anhydrase inhibitors. Synthesis of 2,4,6-trimethylpyridinium derivatives of 2-(hydrazinocarbonyl)-3-aryl-1H-indole-5-sulfonamides acting as potent inhibitors of the tumor-associated isoform IX and XII.
scientific article published on 22 April 2009
Carbonic anhydrase inhibitors. Synthesis of a novel series of 5-substituted 2,4-dichlorobenzenesulfonamides and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII
scientific article published on 13 May 2014
Carbonic anhydrase inhibitors. Synthesis of heterocyclic 4-substituted pyridine-3-sulfonamide derivatives and their inhibition of the human cytosolic isozymes I and II and transmembrane tumor-associated isozymes IX and XII.
scientific article published on 20 September 2013
Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N'-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-as
scientific article published on 10 November 2013
Carbonic anhydrase inhibitors. Synthesis, molecular structures, and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with novel 3-pyridinesulfonamide derivatives
scientific article published on 08 July 2011
Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors
scientific article
Carbonic anhydrase inhibitors. The beta-carbonic anhydrases from the fungal pathogens Cryptococcus neoformans and Candida albicans are strongly inhibited by substituted-phenyl-1H-indole-5-sulfonamides.
scientific article published on 3 March 2010
Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors
scientific article published in December 2005
Carbonic anhydrase inhibitors. The nematode alpha-carbonic anhydrase of Caenorhabditis elegans CAH-4b is highly inhibited by 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides
scientific article published on 27 January 2009
Carbonic anhydrase inhibitors. X-ray crystal studies of the carbonic anhydrase II-trithiocarbonate adduct--an inhibitor mimicking the sulfonamide and urea binding to the enzyme
scientific article
Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies.
scientific article
Carbonic anhydrase inhibitors. inhibition of cytosolic isozymes I and II and transmembrane, cancer-associated isozyme IX with anions
scientific article published in October 2003
Carbonic anhydrase inhibitors: 2-Substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV
scientific article published on 01 November 2008
Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs
scientific article published in March 2006
Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms
scientific article
Carbonic anhydrase inhibitors: Design, synthesis, kinetic, docking and molecular dynamics analysis of novel glycine and phenylalanine sulfonamide derivatives
scientific article published on 23 October 2015
Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX.
scientific article published in January 2004
Carbonic anhydrase inhibitors: Gd(iii) complexes of DOTA- and TETA-sulfonamide conjugates targeting the tumor associated carbonic anhydrase isozymes IX and XII
Carbonic anhydrase inhibitors: Inhibition of cytosolic/tumor-associated isoforms I, II, and IX with iminodiacetic carboxylates/hydroxamates also incorporating benzenesulfonamide moieties
scientific article published on 08 January 2007
Carbonic anhydrase inhibitors: Inhibition of human erythrocyte isozymes I and II with a series of phenolic acids
scientific article published in May 2010
Carbonic anhydrase inhibitors: Inhibition of the cytosolic human isozyme VII with anions
scientific article published on 18 April 2006
Carbonic anhydrase inhibitors: Inhibition of the new membrane-associated isoform XV with phenols
scientific article published on 4 May 2008
Carbonic anhydrase inhibitors: Inhibition of the tumor-associated isozymes IX and XII with polyfluorinated aromatic/heterocyclic sulfonamides
scientific article published in June 2005
Carbonic anhydrase inhibitors: N-(p-sulfamoylphenyl)-alpha-D-glycopyranosylamines as topically acting antiglaucoma agents in hypertensive rabbits
scientific article published in January 2004
Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II and IV.
scientific article
Carbonic anhydrase inhibitors: Schiff's bases of aromatic and heterocyclic sulfonamides and their metal complexes
scientific article published in June 2004
Carbonic anhydrase inhibitors: Selective inhibition of the extracellular, tumor-associated isoforms IX and XII over isozymes I and II with glycosyl-thioureido-sulfonamides
scientific article published on 13 July 2007
Carbonic anhydrase inhibitors: Synthesis and inhibition of the cytosolic mammalian carbonic anhydrase isoforms I, II and VII with benzene sulfonamides incorporating 4,5,6,7-tetrachlorophthalimide moiety
scientific article published on 26 June 2013
Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moietie
scientific article
Carbonic anhydrase inhibitors: The β-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors
scientific article published on 25 April 2007
Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib
scientific article
Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II.
scientific article
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase
scientific article published in January 2004
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a bis-sulfonamide-two heads are better than one?
scientific article published in August 2003
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a topically acting antiglaucoma sulfonamide
scientific article published in May 2004
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride
scientific article published in January 2004
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the perfluorobenzoyl analogue of methazolamide. Implications for the drug design of fluorinated inhibitors
scientific article published in August 2003
Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of 5-amino-1,3,4-thiadiazole-2-sulfonamide and 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole-2-sulfonamide to human isoform II
scientific article published on 26 September 2006
Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of N-substituted benzenesulfonamides to human isoform II
scientific article
Carbonic anhydrase inhibitors: aliphatic N-phosphorylated sulfamates--a novel zinc-anchoring group leading to nanomolar inhibitors
scientific article published in June 2004
Carbonic anhydrase inhibitors: an editorial
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scientific article published on March 6, 2013
Carbonic anhydrase inhibitors: anticonvulsant sulfonamides incorporating valproyl and other lipophilic moieties
scientific article published in January 2002
Carbonic anhydrase inhibitors: aromatic and heterocyclic sulfonamides incorporating adamantyl moieties with strong anticonvulsant activity
scientific article published in May 2004
Carbonic anhydrase inhibitors: benzenesulfonamides incorporating cyanoacrylamide moieties are low nanomolar/subnanomolar inhibitors of the tumor-associated isoforms IX and XII.
scientific article
Carbonic anhydrase inhibitors: binding of an antiglaucoma glycosyl-sulfanilamide derivative to human isoform II and its consequences for the drug design of enzyme inhibitors incorporating sugar moieties
scientific article
Carbonic anhydrase inhibitors: binding of indanesulfonamides to the human isoform II
scientific article
Carbonic anhydrase inhibitors: bioreductive nitro-containing sulfonamides with selectivity for targeting the tumor associated isoforms IX and XII
scientific article
Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori
scientific article published on 3 February 2006
Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides
scientific article
Carbonic anhydrase inhibitors: copper(II) complexes of polyamino-polycarboxylamido aromatic/heterocyclic sulfonamides are very potent inhibitors of the tumor-associated isoforms IX and XII.
scientific article published on 13 November 2007
Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV
scientific article
Carbonic anhydrase inhibitors: design of membrane-impermeant copper(II) complexes of DTPA-, DOTA-, and TETA-tailed sulfonamides targeting the tumor-associated transmembrane isoform IX.
scientific article published in November 2008
Carbonic anhydrase inhibitors: design of spin-labeled sulfonamides incorporating TEMPO moieties as probes for cytosolic or transmembrane isozymes.
scientific article published on 17 May 2008
Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma
scientific article published in September 2005
Carbonic anhydrase inhibitors: design, synthesis, and biological evaluation of novel sulfonyl semicarbazide derivatives.
scientific article published on 16 May 2014
Carbonic anhydrase inhibitors: glycosylsulfanilamides act as subnanomolar inhibitors of the human secreted isoform VI.
scientific article published on 12 October 2009
Carbonic anhydrase inhibitors: guaiacol and catechol derivatives effectively inhibit certain human carbonic anhydrase isoenzymes (hCA I, II, IX and XII)
scientific article published on 06 November 2014
Carbonic anhydrase inhibitors: in vitro inhibition of α isoforms (hCA I, hCA II, bCA III, hCA IV) by flavonoids.
scientific article published on 14 December 2011
Carbonic anhydrase inhibitors: inhibition of Plasmodium falciparum carbonic anhydrase with aromatic/heterocyclic sulfonamides-in vitro and in vivo studies
scientific article
Carbonic anhydrase inhibitors: inhibition of cytosolic carbonic anhydrase isozymes II and VII with simple aromatic sulfonamides and some azo dyes.
scientific article published on 22 June 2009
Carbonic anhydrase inhibitors: inhibition of cytosolic isozymes I and II with sulfamide derivatives
scientific article
Carbonic anhydrase inhibitors: inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with benzo[b]thiophene 1,1-dioxide sulfonamides
scientific article published in November 2005
Carbonic anhydrase inhibitors: inhibition of human and bovine isoenzymes by benzenesulphonamides, cyclitols and phenolic compounds.
scientific article published on 14 October 2011
Carbonic anhydrase inhibitors: inhibition of human and murine mitochondrial isozymes V with anions
scientific journal article
Carbonic anhydrase inhibitors: inhibition of human cytosolic isozyme II and mitochondrial isozyme V with a series of benzene sulfonamide derivatives
scientific article published in November 2004
Carbonic anhydrase inhibitors: inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides.
scientific article
Carbonic anhydrase inhibitors: inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides--solution and crystallographic studies
scientific article
Carbonic anhydrase inhibitors: inhibition of isozymes I, II, and IX with triazole-linked O-glycosides of benzene sulfonamides
scientific article published on 08 March 2007
Carbonic anhydrase inhibitors: inhibition of mammalian isoforms I-XIV with a series of substituted phenols including paracetamol and salicylic acid
scientific article published on 13 June 2008
Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates
scientific article published on 24 December 2008
Carbonic anhydrase inhibitors: inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with simple anions.
scientific article
Carbonic anhydrase inhibitors: inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides
scientific article published on 3 October 2005
Carbonic anhydrase inhibitors: inhibition of the human transmembrane isozyme XIV with a library of aromatic/heterocyclic sulfonamides
scientific article published on 11 July 2005
Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions.
scientific article published in December 2004
Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides
scientific article published in September 2005
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides
scientific article published in March 2003
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with fluorine-containing sulfonamides. The first subnanomolar CA IX inhibitor discovered
scientific article published in May 2004
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozymes IX and XII with a library of aromatic and heteroaromatic sulfonamides
scientific article published in November 2005
Carbonic anhydrase inhibitors: inhibition of the β-class enzyme from the pathogenic yeast Candida glabrata with sulfonamides, sulfamates and sulfamides
scientific article published on 01 March 2013
Carbonic anhydrase inhibitors: inhibition of transmembrane, tumor-associated isozyme IX, and cytosolic isozymes I and II with aliphatic sulfamates
scientific article
Carbonic anhydrase inhibitors: inhibition studies of a coral secretory isoform with inorganic anions
scientific article
Carbonic anhydrase inhibitors: interactions of phenols with the 12 catalytically active mammalian isoforms (CA I-XIV).
scientific article
Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX.
scientific article published in June 2005
Carbonic anhydrase inhibitors: purification and inhibition studies of pigeon (Columba livia var. domestica) red blood cell carbonic anhydrase with sulfonamides
scientific article published on 11 April 2011
Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II.
scientific article published in September 2005
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with N-hydroxysulfamides--a new zinc-binding function in the design of inhibitors.
scientific article
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with bis-sulfamates
scientific article
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide.
scientific article published in December 2004
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating 1,2,4-triazine moieties
scientific article
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating thioureido-sulfanilyl scaffolds.
scientific article
Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, IX and XII with benzene sulfonamides incorporating 4- and 3-nitrophthalimide moieties
scientific article published on 31 January 2014
Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, VII, IX and XII with benzene sulfonamides incorporating 4,5,6,7-tetrabromophthalimide moiety.
scientific article published on 2 August 2013
Carbonic anhydrase inhibitors: synthesis and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with 4-substituted 3-pyridinesulfonamides
scientific article published on 12 February 2010
Carbonic anhydrase inhibitors: synthesis and inhibition studies against mammalian isoforms I-XV with a series of 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides.
scientific article published on 13 September 2008
Carbonic anhydrase inhibitors: synthesis and topical intraocular pressure lowering effects of fluorine-containing inhibitors devoid of enhanced reactivity
scientific article
Carbonic anhydrase inhibitors: synthesis of water soluble sulfonamides incorporating a 4-sulfamoylphenylmethylthiourea scaffold, with potent intraocular pressure lowering properties
scientific article published in October 2002
Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors
scientific article
Carbonic anhydrase inhibitors: the X-ray crystal structure of the adduct of N-hydroxysulfamide with isozyme II explains why this new zinc binding function is effective in the design of potent inhibitors
scientific article
Carbonic anhydrase inhibitors: the first QSAR study on inhibition of tumor-associated isoenzyme IX with aromatic and heterocyclic sulfonamides
scientific article
Carbonic anhydrase inhibitors: the first on-resin screening of a 4-sulfamoylphenylthiourea library
scientific article
Carbonic anhydrase inhibitors: the first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX.
scientific article published in February 2004
Carbonic anhydrase inhibitors: the inhibition profiles of the human mitochondrial isoforms VA and VB with anions are very different
scientific article published on 15 August 2007
Carbonic anhydrase inhibitors: the membrane-associated isoform XV is highly inhibited by inorganic anions.
scientific article published on 25 December 2008
Carbonic anhydrase inhibitors: the very weak inhibitors dithiothreitol, beta-mercaptoethanol, tris(carboxyethyl)phosphine and threitol interfere with the binding of sulfonamides to isozymes II and IX.
scientific article
Carbonic anhydrase inhibitors: thioxolone versus sulfonamides for obtaining isozyme-selective inhibitors?
scientific article published on 12 June 2008
Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating esters and amides of 3- and 4-carboxybenzolamide
scientific article published in September 2003
Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating phthaloyl and phthalimido moieties
scientific article published on January 1, 2001
Carbonic anhydrase inhibitors: transepithelial transport of thioureido sulfonamide inhibitors of the cancer-associated isozyme IX is dependent on efflux transporters
scientific article published in April 2006
Carbonic anhydrase inhibitors: two-prong versus mono-prong inhibitors of isoforms I, II, IX, and XII exemplified by photochromic cis-1,2-alpha-dithienylethene derivatives
scientific article published on 7 February 2009
Carbonic anhydrase inhibitors; fluorinated phenyl sulfamates show strong inhibitory activity and selectivity for the inhibition of the tumor-associated isozymes IX and XII over the cytosolic ones I and II.
scientific article published on 23 July 2009
Carbonic anhydrase inhibitory activity of sulfonamides and carboxylic acids incorporating cyclic imide scaffolds
scientific article
Carbonic anhydrase inhibitory properties of novel sulfonamide derivatives of aminoindanes and aminotetralins
scientific article published on 12 January 2013
Carbonic anhydrase inhibitory properties of some uracil derivatives
scientific article published in December 2017
Carbonic anhydrase modulation of emotional memory. Implications for the treatment of cognitive disorders
scientific article published on 01 December 2020
Carbonic anhydrase regulation and CO(2) sensing in the fungal pathogen Candida glabrata involves a novel Rca1p ortholog
scientific article published on 6 June 2012
Carbonic anhydrase-encoded dynamic constitutional libraries: toward the discovery of isozyme-specific inhibitors
scientific article published in August 2009
Carbonic anhydrases
scientific article published in March 2013
Carbonic anhydrases activation with 3-amino-1H-1,2,4-triazole-1-carboxamides: Discovery of subnanomolar isoform II activators
scientific article published on 24 January 2017
Carbonic anhydrases are producers of S-nitrosothiols from inorganic nitrite and modulators of soluble guanylyl cyclase in human platelets
scientific article published on 29 April 2016
Carbonic anhydrases as drug targets
scientific article published in January 2008
Carbonic anhydrases as drug targets--an overview
scientific article published on January 2007
Carbonic anhydrases as targets for medicinal chemistry
scientific article published on 19 April 2007
Carbonic anhydrases from Trypanosoma and Leishmania as anti-protozoan drug targets
scientific article published on 24 January 2017
Carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani chagasi are inhibited by benzoxaboroles.
scientific article published in December 2018
Carbonic anhydrases in anthozoan corals—A review
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scientific article published on October 30, 2012
Carbonic anhydrases inhibitory effects of new benzenesulfonamides synthesized by using superacid chemistry
scientific article published on 14 December 2011
Carbonic anhydrases--an overview
scientific article published on January 2008
Carbonic anhydrases: again, and again, and again
scientific article published on 01 January 2010
Carbonic anhydrases: current state of the art, therapeutic applications and future prospects
scientific article
Carbonic anhydrases: from biomedical applications of the inhibitors and activators to biotechnological use for CO2 capture
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scientific article published on 01 April 2013
Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
scientific article
Catechols: a new class of carbonic anhydrase inhibitors
scientific article published on 01 October 2020
Chagas Disease: Perspectives on the Past and Present and Challenges in Drug Discovery
scientific article published on 23 November 2020
Challenges and Promises for Obtaining New Antiprotozoal Drugs: What’s Going Wrong?
scientific article published in 2021
Challenging Organic Syntheses and Pharmacological Applications of Natural Products and their Derivatives - Part II
scientific article published on 01 January 2016
Characterization and anions inhibition studies of an α-carbonic anhydrase from the teleost fish Dicentrarchus labrax
scientific article published on 16 December 2010
Characterization and inhibition of the recently discovered carbonic anhydrase isoforms CA XIII, XIV and XV.
scientific article published on January 2007
Characterization and inhibition studies of an α-carbonic anhydrase from the endangered sturgeon species Acipenser gueldenstaedti.
scientific article
Characterization of CA XIII, a novel member of the carbonic anhydrase isozyme family
scientific journal article
Characterization of Carbonic Anhydrase IX Interactome Reveals Proteins Assisting Its Nuclear Localization in Hypoxic Cells
scientific article published on 12 December 2012
Characterization of carbonic anhydrase from Turkish native "Gerze" chicken and influences of metal ions on enzyme activity
scientific article
Characterization of the first beta-class carbonic anhydrase from an arthropod (Drosophila melanogaster) and phylogenetic analysis of beta-class carbonic anhydrases in invertebrates
scientific article
Characterization, bioinformatic analysis and dithiocarbamate inhibition studies of two new α-carbonic anhydrases, CAH1 and CAH2, from the fruit fly Drosophila melanogaster.
scientific article published on 31 August 2012
Chemometric QSAR modeling and in silico design of carbonic anhydrase inhibition of a coral secretory isoform by sulfonamide
scientific article published on 11 September 2012
Chemometric modeling of breast cancer associated carbonic anhydrase IX inhibitors belonging to the ureido-substituted benzene sulfonamide class
scientific article published on 11 February 2014
Chromene-Containing Aromatic Sulfonamides with Carbonic Anhydrase Inhibitory Properties
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journal article from 'International Journal of Molecular Sciences' published in 2021
Chromone containing sulfonamides as potent carbonic anhydrase inhibitors
scientific article published on 10 October 2011
Click chemistry‐based synthesis of new benzenesulfonamide derivatives bearing triazole ring as selective carbonic anhydrase II inhibitors
scientific article published in 2022
Click-tailed benzenesulfonamides as potent bacterial carbonic anhydrase inhibitors for targeting Mycobacterium tuberculosis and Vibrio cholerae
scientific article published on 29 January 2019
Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII
scientific article published on 28 September 2015
Cloning, Characterization and Anion Inhibition Studies of a β-Carbonic Anhydrase from the Pathogenic Protozoan
Cloning, Characterization, and Sulfonamide and Thiol Inhibition Studies of an α-Carbonic Anhydrase from Trypanosoma cruzi, the Causative Agent of Chagas Disease
Cloning, Purification, and Characterization of a β-Carbonic Anhydrase from Malassezia restricta, an Opportunistic Pathogen Involved in Dandruff and Seborrheic Dermatitis
scientific article published on 17 May 2019
Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.
scientific article
Cloning, characterization and anion inhibition studies of a γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea
scientific article published on 6 January 2016
Cloning, characterization and anion inhibition studies of a γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune
scientific article published on 11 March 2015
Cloning, characterization and anion inhibition study of a β-class carbonic anhydrase from the caries producing pathogen Streptococcus mutans
scientific article
Cloning, characterization and anion inhibition study of the δ-class carbonic anhydrase (TweCA) from the marine diatom Thalassiosira weissflogii
scientific article
Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana
scientific article
Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Brucella suis.
scientific article published in March 2010
Cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Leishmania donovani chagasi, the protozoan parasite responsible for leishmaniasis.
scientific article published on 13 September 2013
Cloning, characterization, and sulfonamide and thiol inhibition studies of an α-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease
Cloning, expression and biochemical characterization of a β-carbonic anhydrase from the soil bacterium Enterobacter sp. B13.
scientific article published on 26 October 2015
Cloning, expression and purification of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum
scientific article published on 15 August 2016
Cloning, expression and purification of the α-carbonic anhydrase from the mantle of the Mediterranean mussel, Mytilus galloprovincialis
scientific article published in December 2017
Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV.
scientific article published in February 2009
Cloning, expression, purification and sulfonamide inhibition profile of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum
scientific article published on 28 July 2016
Cloning, polymorphism, and inhibition of beta-carbonic anhydrase of Helicobacter pylori
scientific article
Cloning, purification, kinetic and anion inhibition studies of a recombinant β-carbonic anhydrase from the Atlantic salmon parasite platyhelminth <i>Gyrodactylus salaris</i>
scientific article published on 31 May 2022
Co-targeting intracellular pH and essential amino acid uptake cooperates to induce cell death of T-ALL/LL cells.
scientific article published on 22 June 2017
Combining carbonic anhydrase and thioredoxin reductase inhibitory motifs within a single molecule dramatically increases its cytotoxicity
scientific article published on 01 December 2020
Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies
scientific article
Comparative QSAR study on para-substituted aromatic sulphonamides as CAII inhibitors: information versus topological (distance-based and connectivity) indices
scientific article published on 19 January 2008
Comparison of blood carbonic anhydrase activity of athletes performing interval and continuous running exercise at high altitude
Comparison of the Anion Inhibition Profiles of the α-CA Isoforms (SpiCA1, SpiCA2 and SpiCA3) from the Scleractinian Coral Stylophora pistillata
scientific article published on 21 July 2018
Comparison of the Sulfonamide Inhibition Profiles of the α-Carbonic Anhydrase Isoforms (SpiCA1, SpiCA2 and SpiCA3) Encoded by the Genome of the Scleractinian Coral
scientific article published on 01 March 2019
Comparison of the Sulfonamide Inhibition Profiles of the β- and γ-Carbonic Anhydrases from the Pathogenic Bacterium Burkholderia pseudomallei
scientific article
Comparison of the amine/amino acid activation profiles of the β- and γ-carbonic anhydrases from the pathogenic bacterium Burkholderia pseudomallei.
scientific article published in December 2018
Comparison of the anion inhibition profiles of the β- and γ-carbonic anhydrases from the pathogenic bacterium Burkholderia pseudomallei.
scientific article published on 16 February 2017
Comparison of the sulfonamide inhibition profiles of the α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae
scientific article published on 7 March 2016
Computational investigation of the selectivity of salen and tetrahydrosalen compounds towards the tumor-associated hCA XII isozyme
scientific article published on 25 March 2014
Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms
scientific article
Continued exploration and tail approach synthesis of benzenesulfonamides containing triazole and dual triazole moieties as carbonic anhydrase I, II, IV and IX inhibitors
scientific article published on 12 September 2019
Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment
scientific article published on 21 December 2018
Coral Carbonic Anhydrases: Regulation by Ocean Acidification.
scientific article
Correction to Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins.
scientific article published on 30 June 2015
Correction: Carbonic Anhydrase Protects Fatty Liver Grafts against Ischemic Reperfusion Damage
scientific article published on 25 September 2015
Corrigendum to "Synthesis and carbonic anhydrase inhibitory properties of novel chalcone substituted benzenesulfonamides" [Bioorg. Med. Chem. Lett. 26 (2016) 5867-5870].
scientific article published on 10 July 2017
Coumarin carbonic anhydrase inhibitors from natural sources
scientific article published on 01 December 2020
Coumarin-Thiourea Hybrids Show Potent Carbonic Anhydrase IX and XIII Inhibitory Action
scientific article published on 21 December 2020
Coumarins and other fused bicyclic heterocycles with selective tumor-associated carbonic anhydrase isoforms inhibitory activity.
scientific article published on 29 November 2016
Coumarins from Magydaris pastinacea as inhibitors of the tumour-associated carbonic anhydrases IX and XII: isolation, biological studies and in silico evaluation
scientific article published on 01 December 2020
Coumarins incorporating hydroxy- and chloro-moieties selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II.
scientific article published on 10 June 2010
Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations
scientific article
Coxibs and cardiovascular side-effects: from light to shadow.
scientific article
Crystal Structure of Carbonic Anhydrase II in Complex with an Activating Ligand: Implications in Neuronal Function.
scientific article published on 8 February 2018
Crystal Structure of a Tetrameric Type II β-Carbonic Anhydrase from the Pathogenic Bacterium Burkholderia pseudomallei
scientific article published on 12 May 2020
Crystal analysis of aromatic sulfonamide binding to native and (Zn)2 adduct of human carbonic anhydrase I Michigan 1
Crystal structure and chemical inhibition of essential schistosome host-interactive virulence factor carbonic anhydrase SmCA
scientific article published on 05 September 2019
Crystal structure and kinetic studies of a tetrameric type II β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae
scientific article
Crystal structure of a zinc-activated variant of human carbonic anhydrase I, CA I Michigan 1: evidence for a second zinc binding site involving arginine coordination
scientific article published on 21 May 2002
Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide
scientific article
Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide
scientific article
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX
scientific article
Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor.
scientific article published in December 2018
Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense
scientific article
Crystal structures of two tetrameric β-carbonic anhydrases from the filamentous ascomycete Sordaria macrospora
scientific article
Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes
scientific article
Cyclic tertiary sulfamates: Selective inhibition of the tumor-associated carbonic anhydrases IX and XII by N- and O-substituted acesulfame derivatives
scientific article published on 08 July 2014
Cyclodextrin complexation highly enhances efficacy of arylsulfonylureido benzenesulfonamide carbonic anhydrase inhibitors as a topical antiglaucoma agents
scientific article published on 29 July 2015
Cyclodextrin complexes of sulfonamide carbonic anhydrase inhibitors as long-lasting topically acting antiglaucoma agents
scientific article
Cysteine-modifying agents: a possible approach for effective anticancer and antiviral drugs
scientific article
DNA Cloning, Characterization, and Inhibition Studies of an α-Carbonic Anhydrase from the Pathogenic Bacterium Vibrio cholerae
scientific article published on 04 December 2012
Deciphering the Mechanism of Human Carbonic Anhydrases Inhibition with Sulfocoumarins: Computational and Experimental Studies
scientific article published on 03 May 2018
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins
scientific article
Dendrimers incorporating benzenesulfonamide moieties strongly inhibit carbonic anhydrase isoforms I-XIV
scientific article published on 15 May 2015
Design and Comparative Evaluation of the Anticonvulsant Profile, Carbonic-Anhydrate Inhibition and Teratogenicity of Novel Carbamate Derivatives of Branched Aliphatic Carboxylic Acids with 4-Aminobenzensulfonamide.
scientific article
Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis
scientific article published on 11 January 2017
Design and Validation of FRESH, a Drug Discovery Paradigm Resting on Robust Chemical Synthesis
scientific article published on 3 April 2015
Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII.
scientific article published on 19 May 2015
Design and synthesis of novel 1,3-diaryltriazene-substituted sulfonamides as potent and selective carbonic anhydrase II inhibitors
scientific article published on 15 February 2018
Design and synthesis of novel benzenesulfonamide containing 1,2,3-triazoles as potent human carbonic anhydrase isoforms I, II, IV and IX inhibitors
scientific article published on 08 June 2018
Design and synthesis of thiourea compounds that inhibit transmembrane anchored carbonic anhydrases.
scientific article
Design of weakly basic thrombin inhibitors incorporating novel P1 binding functions: molecular and X-ray crystallographic studies
scientific article
Design of zinc binding functions for carbonic anhydrase inhibitors.
scientific article published on January 2008
Design, Synthesis, and Biological Evaluation of 1,2,3-Triazole-Linked Triazino[5,6-B]Indole-Benzene Sulfonamide Conjugates as Potent Carbonic Anhydrase I, II, IX, and XIII Inhibitors
scientific article published on 15 May 2020
Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology
scientific article published on 09 April 2018
Design, solid-phase synthesis, and biological evaluation of novel 1,5-diarylpyrrole-3-carboxamides as carbonic anhydrase IX inhibitors.
scientific article
Design, synthesis and X-ray crystallography of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects
scientific article published on 19 May 2018
Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold
scientific article published on 01 December 2019
Design, synthesis and biological evaluation of N-(5-methyl-isoxazol-3-yl/1,3,4-thiadiazol-2-yl)-4-(3-substitutedphenylureido) benzenesulfonamides as human carbonic anhydrase isoenzymes I, II, VII and XII inhibitors
scientific article published on 17 June 2016
Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors
scientific article published on 10 March 2020
Design, synthesis and biological evaluation of coumarin-3-carboxamides as selective carbonic anhydrase IX and XII inhibitors
scientific article published on 05 February 2019
Design, synthesis and biological evaluation of novel ureido benzenesulfonamides incorporating 1,3,5-triazine moieties as potent carbonic anhydrase IX inhibitors
article
Design, synthesis and evaluation of 18F-labeled cationic carbonic anhydrase IX inhibitors for PET imaging.
scientific article published in December 2017
Design, synthesis and evaluation of N-substituted saccharin derivatives as selective inhibitors of tumor-associated carbonic anhydrase XII
scientific article published on 10 February 2014
Design, synthesis and molecular modelling studies of some pyrazole derivatives as carbonic anhydrase inhibitors
scientific article published on 01 December 2020
Design, synthesis, and biological evaluation of novel carbohydrate-based sulfamates as carbonic anhydrase inhibitors.
scientific article published on 11 February 2011
Design, synthesis, and carbonic anhydrase inhibition activity of benzenesulfonamide-linked novel pyrazoline derivatives
scientific article published on 19 March 2019
Design, synthesis, and docking studies of new 1,3,4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity
scientific article published on 22 August 2007
Design, synthesis, and evaluation of hydroxamic acid derivatives as promising agents for the management of Chagas disease.
scientific article published on 13 December 2013
Design, synthesis, in vitro inhibition and toxicological evaluation of human carbonic anhydrases I, II and IX inhibitors in 5-nitroimidazole series
scientific article published on 01 December 2020
Designing carbonic anhydrase inhibitors for the treatment of breast cancer.
scientific article published on 20 April 2015
Designing of novel carbonic anhydrase inhibitors and activators.
scientific article
Designing, synthesis and bioactivities of 4-[3-(4-hydroxyphenyl)-5-aryl-4,5-dihydro-pyrazol-1-yl]benzenesulfonamides.
scientific article published on 23 October 2016
Determination of the inhibitory effects of N-methylpyrrole derivatives on glutathione reductase enzyme
scholarly article by Esma Kocaoğlu et al published December 2019 in Journal of Enzyme Inhibition and Medicinal Chemistry
Development and biological evaluation of ⁹⁹mTc-sulfonamide derivatives for in vivo visualization of CA IX as surrogate tumor hypoxia markers
scientific article published on 30 October 2013
Development and ex vivo evaluation of 5-aminolevulinic acid-loaded niosomal formulations for topical photodynamic therapy
article
Development of 3-(4-aminosulphonyl)-phenyl-2-mercapto-3H-quinazolin-4-ones as inhibitors of carbonic anhydrase isoforms involved in tumorigenesis and glaucoma
scientific article published on 08 February 2016
Development of Thiazolidinones as Fungal Carbonic Anhydrase Inhibitors
scientific article published on 22 April 2020
Development of a Fingerprint-Based Scoring Function for the Prediction of the Binding Mode of Carbonic Anhydrase II Inhibitors.
scientific article published on 23 June 2018
Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors
scientific article published on 01 December 2020
Development of certain new 2-substituted-quinazolin-4-yl-aminobenzenesulfonamide as potential antitumor agents.
scientific article published on 6 January 2016
Development of oxathiino[6,5-b]pyridine 2,2-dioxide derivatives as selective inhibitors of tumor-related carbonic anhydrases IX and XII
scientific article published on 06 May 2020
Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups
scientific article
Development of small molecule carbonic anhydrase IX inhibitors
scientific article published on June 2008
Development of sulfonamides incorporating phenylacrylamido functionalities as carbonic anhydrase isoforms I, II, IX and XII inhibitors.
scientific article published in September 2017
Diagnostic markers for glaucoma: a patent and literature review (2013-2019)
scientific article published on 18 September 2019
Dihalogenated sulfanilamides and benzolamides are effective inhibitors of the three β-class carbonic anhydrases from Mycobacterium tuberculosis
scientific article published on 03 January 2012
Dioxygen, an unexpected carbonic anhydrase ligand.
scientific article published in December 2018
Dipotassium-trioxohydroxytetrafluorotriborate, K₂[B₃O₃F₄OH], is a potent inhibitor of human carbonic anhydrases
scientific article published on 18 June 2014
Direct and straightforward access to substituted alkyl selenols as novel carbonic anhydrase inhibitors
scientific article published on 30 October 2019
Direct extracellular interaction between carbonic anhydrase IV and the human NBC1 sodium/bicarbonate co-transporter
scientific article
Disclosing the Interaction of Carbonic Anhydrase IX with Cullin-Associated NEDD8-Dissociated Protein 1 by Molecular Modeling and Integrated Binding Measurements
scientific article published on 7 April 2017
Discovering a new class of antifungal agents that selectively inhibits microbial carbonic anhydrases
scientific article published on 01 December 2018
Discovery and microassay of a nitrite-dependent carbonic anhydrase activity by stable-isotope dilution gas chromatography-mass spectrometry
scientific article published on 3 September 2015
Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors
scientific article
Discovery of 4-Hydroxy-3-(3-(phenylureido)benzenesulfonamides as SLC-0111 Analogues for the Treatment of Hypoxic Tumors Overexpressing Carbonic Anhydrase IX
scientific article published on 17 July 2018
Discovery of 4-sulfamoyl-phenyl-β-lactams as a new class of potent carbonic anhydrase isoforms I, II, IV and VII inhibitors: The first example of subnanomolar CA IV inhibitors.
scientific article published on 19 November 2016
Discovery of Benzenesulfonamide Derivatives as Carbonic Anhydrase Inhibitors with Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Evaluation.
scientific article published on 22 March 2018
Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment.
scientific article
Discovery of HIV Type 1 Aspartic Protease Hit Compounds through Combined Computational Approaches.
scientific article
Discovery of New Potential Anti-Infective Compounds Based on Carbonic Anhydrase Inhibitors by Rational Target-Focused Repurposing Approaches.
scientific article
Discovery of New Selenoureido Analogues of 4-(4-Fluorophenylureido)benzenesulfonamide as Carbonic Anhydrase Inhibitors.
scientific article published on 10 August 2017
Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases.
scientific article published on 21 November 2017
Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Management of Rheumatoid Arthritis
scientific article published on 21 May 2018
Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action
scientific article published on 20 February 2020
Discovery of Strecker-type α-aminonitriles as a new class of human carbonic anhydrase inhibitors using differential scanning fluorimetry.
scientific article published on 16 March 2016
Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum--the η-carbonic anhydrases
scientific article (publication date: 15 September 2014)
Discovery of curcumin inspired sulfonamide derivatives as a new class of carbonic anhydrase isoforms I, II, IX, and XII inhibitors
scientific article published in December 2017
Discovery of first-in-class multi-target adenosine A2A receptor antagonists-carbonic anhydrase IX and XII inhibitors. 8-Amino-6-aryl-2-phenyl-1,2,4-triazolo [4,3-a]pyrazin-3-one derivatives as new potential antitumor agents
scientific article published on 12 June 2020
Discovery of low nanomolar and subnanomolar inhibitors of the mycobacterial beta-carbonic anhydrases Rv1284 and Rv3273
scientific journal article
Discovery of new 2, 5-disubstituted 1,3-selenazoles as selective human carbonic anhydrase IX inhibitors with potent anti-tumor activity
scientific article published on 03 September 2018
Discovery of new organoselenium compounds as antileishmanial agents
scientific article published on 31 January 2019
Discovery of new ureido benzenesulfonamides incorporating 1,3,5-triazine moieties as carbonic anhydrase I, II, IX and XII inhibitors
scientific article published on 01 March 2019
Discovery of novel 1,3-diaryltriazene sulfonamides as carbonic anhydrase I, II, VII, and IX inhibitors
scholarly article by Suleyman Akocak et al published December 2018 in Journal of Enzyme Inhibition and Medicinal Chemistry
Discovery of novel isatin-based sulfonamides with potent and selective inhibition of the tumor-associated carbonic anhydrase isoforms IX and XII
scientific article published on 13 May 2015
Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in vitro and in vivo appraisal
scientific article published on 09 July 2018
Discovery of potent carbonic anhydrase and acetylcholine esterase inhibitors: novel sulfamoylcarbamates and sulfamides derived from acetophenones
scientific article published on 14 April 2015
Discovery of thiazolin-4-one-based aromatic sulfamates as a new class of carbonic anhydrase isoforms I, II, IV, and IX inhibitors.
scientific article published on 27 January 2018
Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy
scientific article published on 13 June 2018
Dissecting the inhibition mechanism of cytosolic versus transmembrane carbonic anhydrases by ESR
scientific article
Dithiocarbamates Strongly Inhibit Carbonic Anhydrases and Show Antiglaucoma Action in Vivo
scientific article
Dithiocarbamates are strong inhibitors of the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candida albicans and Candida glabrata
scientific article published on 11 December 2011
Dithiocarbamates effectively inhibit the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa.
scientific article published on 27 December 2016
Dithiocarbamates strongly inhibit the β-class carbonic anhydrases from Mycobacterium tuberculosis
scientific article published on 6 December 2011
Dithiocarbamates with potent inhibitory activity against the Saccharomyces cerevisiae β-carbonic anhydrase.
scientific article published on 11 February 2015
Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations
scientific article
Diuretics with carbonic anhydrase inhibitory action: a patent and literature review (2005 – 2013)
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scientific article published on March 14, 2013
Diuretics: from classical carbonic anhydrase inhibitors to novel applications of the sulfonamides
scientific article published on January 2008
Dominant behaviours in the expression of human carbonic anhydrase hCA I activity
scientific article published on 01 July 2014
Drosophila melanogaster: a model organism for controlling Dipteran vectors and pests.
scientific article published on 08 September 2014
Drug Design Studies of Carbonic Anhydrase Activators
scholarly article
Drug Design of Antiobesity Carbonic Anhydrase Inhibitors
Drug Screening in Human Cells by NMR Spectroscopy Allows the Early Assessment of Drug Potency
scientific article published on 05 February 2020
Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors
scientific article published on 15 February 2016
Dual Cyclooxygenase and Carbonic Anhydrase Inhibition by Nonsteroidal Anti-Inflammatory Drugs for the Treatment of Cancer
scientific article published on 16 July 2015
Dual P-Glycoprotein and CA XII Inhibitors: A New Strategy to Reverse the P-gp Mediated Multidrug Resistance (MDR) in Cancer Cells
scientific article published on 10 April 2020
Dual carbonic anhydrase--cyclooxygenase-2 inhibitors
scientific article published on January 2007
Dual carbonic anhydrase/matrix metalloproteinase inhibitors incorporating bisphosphonic acid moieties targeting bone tumors
scientific article published on 30 April 2014
Dual inhibitors for aspartic proteases HIV-1 PR and renin: advancements in AIDS-hypertension-diabetes linkage via molecular dynamics, inhibition assays, and binding free energy calculations
scientific article published on 18 June 2012
Dual inhibitors of matrix metalloproteinases and carbonic anhydrases: iminodiacetyl-based hydroxamate-benzenesulfonamide conjugates.
scientific article published in December 2008
Dual targeting of cancer-related human matrix metalloproteinases and carbonic anhydrases by chiral N-(biarylsulfonyl)-phosphonic acids
scientific article published in December 2017
Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the tumor-associated hCA IX isoform.
scientific article published on 10 April 2018
Dynameric host frameworks for the activation of lipase through H-bond and interfacial encapsulation
scientific article published on 08 November 2016
Dynamic encapsulation and activation of carbonic anhydrase in multivalent dynameric host matrices
scientific article published on 19 February 2016
ESI mass spectrometry and X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme
scientific article
Editorial: Challenging Organic Syntheses and Pharmacological Applications of Natural Products and their Derivatives
scientific article published on 01 January 2015
Effect of Carbonic Anhydrase IX inhibitors on human endothelial cell survival
scientific article published on 30 May 2020
Effect of Sulfonamides and Their Structurally Related Derivatives on the Activity of ι-Carbonic Anhydrase from Burkholderia territorii
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journal article from 'International Journal of Molecular Sciences' published in 2021
Effect of incorporating a thiophene tail in the scaffold of acetazolamide on the inhibition of human carbonic anhydrase isoforms I, II, IX and XII
scientific article
Effect of sulfonamides as carbonic anhydrase VA and VB inhibitors on mitochondrial metabolic energy conversion
scientific article published on 11 July 2012
Effective Access to Multivalent Inhibitors of Carbonic Anhydrases Promoted by Peptide Bioconjugation.
scientific article
Effects of New NSAID-CAI Hybrid Compounds in Inflammation and Lung Fibrosis
scientific article published on 10 September 2020
Effects of Phosphorylation on the Activity, Inhibition and Stability of Carbonic Anhydrases
scientific article published on 25 May 2023
Effects of dipotassium-trioxohydroxytetrafluorotriborate, K2[B3O3F4OH], on cell viability and gene expression of common human cancer drug targets in a melanoma cell line
scientific article published on 26 August 2015
Effects of dopaminergic compounds on carbonic anhydrase isozymes I, II, and VI
scientific article published on 23 June 2011
Effects of low molecular weight plasma inhibitors of rainbow trout (Oncorhynchus mykiss) on human erythrocyte carbonic anhydrase-II isozyme activity in vitro and rat erythrocytes in vivo
scientific article published in February 2005
Effects of phosphorylation on the activity, inhibition and stability of carbonic anhydrases
scientific article published on 5 April 2023
Efficient Expression and Crystallization System of Cancer-Associated Carbonic Anhydrase Isoform IX
scientific article
Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents
scientific article published on 02 November 2018
Enzyme Inhibition and more− A Tribute to John Smith
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scientific article published on June 1, 2011
Epithelial carbonic anhydrases facilitate PCO2 and pH regulation in rat duodenal mucosa
scientific article
Eriocitrin and Apigenin as New Carbonic Anhydrase VA Inhibitors from a Virtual Screening of Calabrian Natural Products.
scientific article published on 15 January 2015
Erratum for: Eriocitrin and Apigenin as New Carbonic Anhydrase VA Inhibitors from a Virtual Screening of Calabrian Natural Products
scientific article published on 27 January 2015
Escherichia coli γ-carbonic anhydrase: characterisation and effects of simple aromatic/heterocyclic sulphonamide inhibitors
scientific article published on 01 December 2020
Estimation of human carbonic anhydrase II inhibition using topological indices and their combination with quantum-theoretical descriptors
scientific article published in January 2008
Ethylene bis-imidazoles are highly potent and selective activators for isozymes VA and VII of carbonic anhydrase, with a potential nootropic effect
scientific article published on 25 April 2014
Evaluation of 99mTc-sulfonamide and sulfocoumarin derivatives for imaging carbonic anhydrase IX expression
scientific article published on 13 April 2018
Evaluation of Thio- and Seleno-Acetamides Bearing Benzenesulfonamide as Inhibitor of Carbonic Anhydrases from Different Pathogenic Bacteria
scientific article published on 17 January 2020
Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models.
scientific article
Evaluation of selenide, diselenide and selenoheterocycle derivatives as carbonic anhydrase I, II, IV, VII and IX inhibitors.
scientific article published on 6 March 2017
Evaluation of sulphonamide derivatives acting as inhibitors of human carbonic anhydrase isoforms I, II and Mycobacterium tuberculosis β-class enzyme Rv3273.
scientific article
Evaluation of the anticancer potential of a sulphonamide carbonic anhydrase IX inhibitor on cervical cancer cells
scientific article published on 01 December 2019
Evidence for a plasma-accessible carbonic anhydrase in the lumen of salmon heart that may enhance oxygen delivery to the myocardium
scientific article published in March 2016
Expanding the anticancer potential of 1,2,3-triazoles via simultaneously targeting Cyclooxygenase-2, 15-lipoxygenase and tumor-associated carbonic anhydrases
scientific article published on 25 May 2020
Experimental Carbonic Anhydrase Inhibitors for the Treatment of Hypoxic Tumors
scientific article published on 15 December 2020
Exploiting the hydrophobic and hydrophilic binding sites for designing carbonic anhydrase inhibitors
scientific article published on 30 April 2013
Exploration of the binding mode of indanesulfonamides as selective inhibitors of human carbonic anhydrase type VII by targeting Lys 91.
scientific article published on September 2007
Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approach
scientific article published on 01 December 2019
Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors.
scientific article published on 31 July 2017
Exploring QSARs of some benzenesulfonamides incorporating cyanoacrylamide moieties as a carbonic anhydrase inhibitors (specifically against tumor-associated isoforms IX and XII).
scientific article published on 8 September 2014
Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity
scientific article published on 01 December 2019
Exploring carbonic anhydrase inhibition with multimeric coumarins displayed on a fullerene scaffold.
scientific article published in July 2015
Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies
scientific article published on 01 August 2015
Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases
scientific article published on 01 December 2019
Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety
scientific article published on 01 December 2018
Exploring structure-activity relationship of S-substituted 2-mercaptoquinazolin-4(3H)-one including 4-ethylbenzenesulfonamides as human carbonic anhydrase inhibitors
scientific article published on 01 December 2020
Exploring the multiple binding modes of inhibitors to carbonic anhydrases for novel drug discovery
scientific article published on 25 March 2020
Exponential Activation of Carbonic Anhydrase by Encapsulation in Dynameric Host Matrices with Chiral Discrimination
scientific article published on 9 November 2017
Expression and characterization of a recombinant psychrophilic γ-carbonic anhydrase (NcoCA) identified in the genome of the Antarctic cyanobacteria belonging to the genus Nostoc
scientific article published on 30 July 2015
Expression of CA-IX is associated with advanced stage tumors and poor survival in oral squamous cell carcinoma patients.
scientific article published on 4 April 2012
Extending the Inhibition Profiles of Coumarin-Based Compounds Against Human Carbonic Anhydrases: Synthesis, Biological, and In Silico Evaluation
scientific article published on 04 October 2019
Extending the γ-class carbonic anhydrases inhibition profiles with phenolic compounds
scientific article published on 03 October 2019
External pH influences the transcriptional profile of the carbonic anhydrase, CAH-4b in Caenorhabditis elegans
scientific article published on 3 July 2008
Extramitochondrial domain rich in carbonic anhydrase activity improves myocardial energetics
scientific article published on 19 February 2013
Extrinsic acidosis suppresses glycolysis and migration while increasing network formation in pulmonary microvascular endothelial cells
scientific article published on 01 May 2019
Facilitation by intracellular carbonic anhydrase of Na+ -HCO3- co-transport but not Na+ / H+ exchange activity in the mammalian ventricular myocyte.
scientific article published on 2 December 2013
Famotidine, an Antiulcer Agent, Strongly Inhibits and Human Carbonic Anhydrases
Ferrier sulfamidoglycosylation of glycals catalyzed by nitrosonium tetrafluoroborate: towards new carbonic anhydrase glycoinhibitors
scientific article published on 02 October 2014
Fibrate-based N-acylsulphonamides targeting carbonic anhydrases: synthesis, biochemical evaluation, and docking studies
scientific article published on 01 December 2019
First evaluation of organotellurium derivatives as carbonic anhydrase I, II, IV, VII and IX inhibitors.
scientific article published on 5 December 2017
Five- and Six-Membered Nitrogen-Containing Compounds as Selective Carbonic Anhydrase Activators.
scientific article published on 9 December 2017
Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins
scientific article published on 27 March 2012
Flow synthesis and biological activity of aryl sulfonamides as selective carbonic anhydrase IX and XII inhibitors
scientific article published on 04 June 2014
Fluorescence- and spin-labeled carbonic anhydrase inhibitors
scientific article published on January 2008
Fluorescent Silica Nanoparticles with Multivalent Inhibitory Effects towards Carbonic Anhydrases
scientific article published on 12 May 2015
Fluorescent Silica Nanoparticles with Multivalent Inhibitory Effects towards Carbonic Anhydrases
scientific article published on 8 June 2015
Fluorescent sulfonamide carbonic anhydrase inhibitors incorporating 1,2,3-triazole moieties: Kinetic and X-ray crystallographic studies
scholarly article by Fabrizio Carta published in January 2016
Fluorinated pyrrolidines and piperidines incorporating tertiary benzenesulfonamide moieties are selective carbonic anhydrase II inhibitors
scientific article published on 28 November 2014
Fluoroenesulphonamides: N-sulphonylurea isosteres showing nanomolar selective cancer-related transmembrane human carbonic anhydrase inhibition
From random to rational: A discovery approach to selective subnanomolar inhibitors of human carbonic anhydrase IV based on the Castagnoli-Cushman multicomponent reaction
scientific article published on 26 August 2019
Fullerene-based inhibitors of HIV-1 protease
scientific article published on December 2015
Furazan and furoxan sulfonamides are strong α-carbonic anhydrase inhibitors and potential antiglaucoma agents
scientific article published on 17 June 2014
Further validation of strecker-type α-aminonitriles as a new class of potent human carbonic anhydrase II inhibitors: hit expansion within the public domain using differential scanning fluorimetry leads to chemotype refinement
scientific article published on 01 December 2020
Generation and characterization of the first inhibitory antibody targeting tumour-associated carbonic anhydrase XII.
scientific article published on 5 February 2011
Geographical characterization by MAE-HPLC and NIR methodologies and carbonic anhydrase inhibition of Saffron components.
scientific article published on 19 November 2016
Glaucoma and the applications of carbonic anhydrase inhibitors
scientific article published on January 2014
Glycomimetic Based Approach toward Selective Carbonic Anhydrase Inhibitors
scientific article published on 11 March 2020
Glycosidic carbonic anhydrase IX inhibitors: a sweet approach against cancer
scientific article
Glycosyl coumarin carbonic anhydrase IX and XII inhibitors strongly attenuate the growth of primary breast tumors.
scientific article published on 22 November 2011
Handling drug-target selectivity: A study on ureido containing Carbonic Anhydrase inhibitors
scientific article published on 21 November 2020
Heavy metal ion inhibition studies of human, sheep and fish α-carbonic anhydrases.
scientific article published on 7 December 2011
Heterocoumarins Are Selective Carbonic Anhydrase IX and XII Inhibitors with Cytotoxic Effects against Cancer Cells Lines
scientific article published on 29 August 2018
Heterocyclic compounds and their uses: a patent evaluation of WO2010151735A2
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scientific article published on March 25, 2011
Heterocyclic periphery in the design of carbonic anhydrase inhibitors: 1,2,4-Oxadiazol-5-yl benzenesulfonamides as potent and selective inhibitors of cytosolic hCA II and membrane-bound hCA IX isoforms.
scientific article
Heterocyclic urea derivatives and methods of use thereof (WO2010142978)
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scientific article published on January 20, 2012
Highly active antiretroviral therapy: current state of the art, new agents and their pharmacological interactions useful for improving therapeutic outcome
scientific article
Highly hydrophilic 1,3-oxazol-5-yl benzenesulfonamide inhibitors of carbonic anhydrase II for reduction of glaucoma-related intraocular pressure
scientific article published on 04 September 2019
Hit Recycling: Discovery of a Potent Carbonic Anhydrase Inhibitor by in Silico Target Fishing.
scientific article published in July 2015
Homology Modeling and Receptor-Based 3D-QSAR Study of Carbonic Anhydrase IX
scientific article published on 20 October 2007
How many carbonic anhydrase inhibition mechanisms exist?
scientific article
Human Carbonic Anhydrases: Catalytic Properties, Structural Features, and Tissue Distribution
Human carbonic anhydrase VII protects cells from oxidative damage.
scientific article published in October 2013
Human carbonic anhydrase inhibitory profile of mono- and bis-sulfonamides synthesized via a direct sulfochlorination of 3- and 4-(hetero)arylisoxazol-5-amine scaffolds
scientific article published on 13 February 2017
Human carbonic anhydrases and post-translational modifications: a hidden world possibly affecting protein properties and functions
scientific article published on 01 December 2020
Hydrophobic substituents of the phenylmethylsulfamide moiety can be used for the development of new selective carbonic anhydrase inhibitors
scientific article published on 2 September 2014
Hydroxamate represents a versatile zinc binding group for the development of new carbonic anhydrase inhibitors
scientific article
Hydroxamic acid derivatives: a promising scaffold for rational compound optimization in Chagas disease
scientific article published on September 2015
Hydroxylamine-O-sulfonamide is a versatile lead compound for the development of carbonic anhydrase inhibitors.
scientific article published on July 2015
Hydroxyurea is a carbonic anhydrase inhibitor
scientific article published in May 2003
Hyperchlorhidrosis caused by homozygous mutation in CA12, encoding carbonic anhydrase XII
scientific article
Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH.
scientific article
Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including acetazolamide in human glioblastoma.
scientific article published on 12 April 2013
Hypoxia-Activated Prodrug Derivatives of Carbonic Anhydrase Inhibitors in Benzenesulfonamide Series: Synthesis and Biological Evaluation
scientific article published on 18 May 2020
Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates
scientific article
Identification and characterization of a novel zebrafish (Danio rerio) pentraxin-carbonic anhydrase
scientific article published on 7 December 2017
Identification and characterization of the α-CA in the outer membrane vesicles produced by Helicobacter pylori
scientific article published on 01 December 2019
Identification and inhibition of carbonic anhydrases from nematodes.
scientific article
Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as potent carbonic anhydrase inhibitors: synthesis, biological evaluation, and enzyme--ligand X-ray studies
scientific article
Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit
scientific article published on 04 September 2018
Identification of potent and selective human carbonic anhydrase VII (hCA VII) inhibitors
scientific article published in June 2010
Imaging of CA IX with fluorescent labelled sulfonamides distinguishes hypoxic and (re)-oxygenated cells in a xenograft tumour model
scientific article published on 16 July 2009
Imaging the hypoxia surrogate marker CA IX requires expression and catalytic activity for binding fluorescent sulfonamide inhibitors
scientific article published on 14 May 2007
Immunohistochemical study of carbonic anhydrase isozymes in human skin
scientific article published on September 2003
Improving the carbonic anhydrase inhibition profile of the sulfamoylphenyl pharmacophore by attachment of carbohydrate moieties.
scientific article published on 2 November 2017
In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with IX and XII hCA Inhibition
scientific article published on 21 August 2020
In Silico-Guided Identification of New Potent Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae
scientific article published on 01 September 2020
In Vitro inhibition of human carbonic anhydrase I and II isozymes with natural phenolic compounds
scientific article published on 25 March 2011
In silico drug screening approach for the design of magic bullets: a successful example with anti-HIV fullerene derivatized amino acids
scientific article
In silico modeling of β-carbonic anhydrase inhibitors from the fungus Malassezia globosa as antidandruff agents
scientific article published on 6 May 2015
In vitro antibacterial, antifungal & cytotoxic activity of some isonicotinoylhydrazide Schiff's bases and their cobalt (II), copper (II), nickel (II) and zinc (II) complexes
scientific article published in February 2006
In vitro inhibition of Mycobacterium tuberculosis β-carbonic anhydrase 3 with Mono- and dithiocarbamates and evaluation of their toxicity using zebrafish developing embryos
scientific article published on 01 December 2020
In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II.
scientific article published on 13 September 2008
In vitro inhibition of α-carbonic anhydrase isozymes by some phenolic compounds.
scientific article published on 25 May 2011
In vivo imaging and quantification of carbonic anhydrase IX expression as an endogenous biomarker of tumor hypoxia
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scientific article published on November 30, 2012
In-vitro antibacterial and cytotoxic activity of cobalt (ii), copper (ii), nickel (ii) and zinc (ii) complexes of the antibiotic drug cephalothin (Keflin).
scientific article
In-vitro antibacterial, antifungal and cytotoxic activities of some coumarins and their metal complexes
scientific article
In-vitro antibacterial, antifungal and cytotoxic activity of cobalt (II), copper (II), nickel (II) and zinc (II) complexes with furanylmethyl- and thienylmethyl-dithiolenes: [1, 3-dithiole- 2-one and 1,3-dithiole-2-thione].
scientific article published in December 2006
In-vitro antibacterial, antifungal and cytotoxic properties of metal-based furanyl derived sulfonamides
scientific article published in December 2006
In-vitro antibacterial, antifungal and cytotoxic properties of sulfonamide--derived Schiff's bases and their metal complexes
scientific article published in April 2005
Inclusion of a 5-fluorouracil moiety in nitrogenous bases derivatives as human carbonic anhydrase IX and XII inhibitors produced a targeted action against MDA-MB-231 and T47D breast cancer cells
scientific article published on 03 February 2020
Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: structure-activity relationship and pharmacological evaluation
scientific article
Indanesulfonamides as carbonic anhydrase inhibitors. Toward structure-based design of selective inhibitors of the tumor-associated isozyme CA IX
scientific article published on 01 May 2006
Indazole, Pyrazole, and Oxazole Derivatives Targeting Nitric Oxide Synthases and Carbonic Anhydrases.
scientific article published on 5 July 2016
Indisulam. Eisai
scientific article published on 01 November 2002
Indisulam: an anticancer sulfonamide in clinical development
scientific article
Indole-Based Hydrazones Containing A Sulfonamide Moiety as Selective Inhibitors of Tumor-Associated Human Carbonic Anhydrase Isoforms IX and XII.
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scientific article
Influence of hypoxia-dependent factors on the progression of neuroblastoma
scientific article published on 28 October 2015
Inhibition and binding studies of carbonic anhydrase isozymes I, II and IX with benzimidazo[1,2-c][1,2,3]thiadiazole-7-sulphonamides
scientific article
Inhibition of Bacterial Carbonic Anhydrases and Zinc Proteases: From Orphan Targets to Innovative New Antibiotic Drugs
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scientific article published on January 1, 2012
Inhibition of Bacterial Carbonic Anhydrases as a Novel Approach to Escape Drug Resistance
scientific article published on 3 January 2017
Inhibition of Bone Marrow-Mesenchymal Stem Cell-Induced Carbonic Anhydrase IX Potentiates Chemotherapy Efficacy in Triple-Negative Breast Cancer Cells
Inhibition of Malassezia globosa carbonic anhydrase with phenols
scientific article published on 18 March 2017
Inhibition of V-ATPase and carbonic anhydrases as interference strategy with tumor acidification processes
scientific article published on January 2012
Inhibition of acetylcholinesterase and butyrylcholinesterase with uracil derivatives: kinetic and computational studies
scientific article published on 01 December 2019
Inhibition of bacterial α-, β- and γ-class carbonic anhydrases with selenazoles incorporating benzenesulfonamide moieties
scientific article published on 01 December 2019
Inhibition of beta-carbonic anhydrases from the bacterial pathogen Brucella suis with inorganic anions
scientific article published on 24 February 2012
Inhibition of carbonic anhydrase IX as a novel anticancer mechanism
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scientific article published on July 10, 2012
Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one
scientific article published on 10 April 2018
Inhibition of carbonic anhydrase IX: a new strategy against cancer
scientific article published on July 2009
Inhibition of carbonic anhydrase from Trypanosoma cruzi for the management of Chagas disease: an underexplored therapeutic opportunity
scientific article published on 22 February 2016
Inhibition of carbonic anhydrase isoforms I, II, IV, VII and XII with carboxylates and sulfonamides incorporating phthalimide/phthalic anhydride scaffolds
scientific article
Inhibition of carbonic anhydrase isoforms I, II, IX and XII with Schiff's bases incorporating iminoureido moieties
scientific article published on 04 September 2015
Inhibition of carbonic anhydrase isoforms I, II, IX and XII with novel Schiff bases: identification of selective inhibitors for the tumor-associated isoforms over the cytosolic ones
scientific article published on 21 September 2014
Inhibition of carbonic anhydrase isoforms I, II, IX and XII with secondary sulfonamides incorporating benzothiazole scaffolds
scientific article published on 08 January 2016
Inhibition of carbonic anhydrase isozymes I and II with natural products extracted from plants, mushrooms and honey.
scientific article published on 8 July 2011
Inhibition of carbonic anhydrase isozymes I, II and IX with benzenesulfonamides containing an organometallic moiety
scientific article published on 19 July 2007
Inhibition of carbonic anhydrase isozymes with benzene sulfonamides incorporating thio, sulfinyl and sulfonyl glycoside moieties.
scientific article published on 26 February 2009
Inhibition of carbonic anhydrases IX/XII by SLC-0111 boosts cisplatin effects in hampering head and neck squamous carcinoma cell growth and invasion
scientific article published on 02 April 2022
Inhibition of carbonic anhydrases by a substrate analog: benzyl carbamate directly coordinates the catalytic zinc ion mimicking bicarbonate binding
scientific article published on 01 September 2018
Inhibition of carbonic anhydrases from the extremophilic bacteria Sulfurihydrogenibium yellostonense (SspCA) and S. azorense (SazCA) with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cy
scientific article
Inhibition of carbonic anhydrases with glycosyltriazole benzene sulfonamides
scientific article
Inhibition of human carbonic anhydrase isoforms I-XIV with sulfonamides incorporating fluorine and 1,3,5-triazine moieties
scientific article
Inhibition of human carbonic anhydrase isozymes I, II, IX and XII with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties
scientific article published on 25 March 2014
Inhibition of human mitochondrial carbonic anhydrases VA and VB with para-(4-phenyltriazole-1-yl)-benzenesulfonamide derivatives.
scientific article published on 10 July 2008
Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters
scientific article published on 20 October 2015
Inhibition of mammalian carbonic anhydrases I-XIV with grayanotoxin III: solution and in silico studies.
scientific article
Inhibition of membrane-associated carbonic anhydrase isozymes IX, XII and XIV with a library of glycoconjugate benzenesulfonamides
scientific article
Inhibition of monoamine oxidase-A activity in rat brain by synthetic hydrazines: structure-activity relationship (SAR).
scientific article published in June 2005
Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells.
scientific article
Inhibition of the R1 fragment of the cadmium-containing zeta-class carbonic anhydrase from the diatom Thalassiosira weissflogii with anions.
scientific article published on July 2010
Inhibition of the alpha- and beta-carbonic anhydrases from the gastric pathogenHelycobacter pyloriwith anions
scientific article published on 03 February 2012
Inhibition of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases
scientific article published on January 2007
Inhibition of the newly discovered β‑carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with inorganic anions and small molecules
scientific article published on 07 October 2020
Inhibition of the α-carbonic anhydrase from Vibrio cholerae with amides and sulfonamides incorporating imidazole moieties.
scientific article published in December 2017
Inhibition of the β-carbonic anhydrase from Streptococcus pneumoniae by inorganic anions and small molecules: Toward innovative drug design of antiinfectives?
scientific article published on 14 December 2010
Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates.
scientific article published in December 2017
Inhibition of the β-carbonic anhydrase from the protozoan pathogen <i>Trichomonas vaginalis</i> with sulphonamides
scientific article published on 01 December 2021
Inhibition of the β-carbonic anhydrases from Mycobacterium tuberculosis with C-cinnamoyl glycosides: Identification of the first inhibitor with anti-mycobacterial activity
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scientific article published on February 1, 2013
Inhibition of the β-class carbonic anhydrases from Mycobacterium tuberculosis with carboxylic acids
scientific article published on 3 February 2012
Inhibition of tumor-associated human carbonic anhydrase isozymes IX and XII by a new class of substituted-phenylacetamido aromatic sulfonamides
scientific article published on 20 June 2013
Inhibition of α-, β-, γ-, and δ-carbonic anhydrases from bacteria and diatoms with N'-aryl-N-hydroxy-ureas
scientific article published on 01 December 2018
Inhibition of α-, β-, γ-, δ-, ζ- and η-class carbonic anhydrases from bacteria, fungi, algae, diatoms and protozoans with famotidine
scientific article published on 01 December 2019
Inhibition of α-class cytosolic human carbonic anhydrases I, II, IX and XII, and β-class fungal enzymes by carboxylic acids and their derivatives: new isoform-I selective nanomolar inhibitors
scientific article published on 2 August 2012
Inhibition of β-carbonic anhydrases from Brucella suis with C-cinnamoyl glycosides incorporating the phenol moiety
scientific article published on 13 February 2015
Inhibition of β-carbonic anhydrases with ureido-substituted benzenesulfonamides
article
Inhibition pattern of sulfamide-related compounds in binding to carbonic anhydrase isoforms I, II, VII, XII and XIV
scientific article published on 29 November 2012
Inhibition studies of Brucella suis β-carbonic anhydrases with a series of 4-substituted pyridine-3-sulphonamides.
scientific article published in December 2018
Inhibition studies of a beta-carbonic anhydrase from Brucella suis with a series of water soluble glycosyl sulfanilamides.
scientific article published on 21 February 2010
Inhibition studies of bacterial, fungal and protozoan β-class carbonic anhydrases with Schiff bases incorporating sulfonamide moieties
scientific article published on 26 June 2015
Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I–XIV
scientific article published on 01 December 2014
Inhibition studies of quinazoline-sulfonamide derivatives against the γ-CA (PgiCA) from the pathogenic bacterium, Porphyromonas gingivalis
scientific article published on 19 November 2014
Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates
scientific article published on 24 June 2011
Inhibition studies on a panel of human carbonic anhydrases with N1-substituted secondary sulfonamides incorporating thiazolinone or imidazolone-indole tails.
scientific article published in December 2018
Inhibition studies with anions and small molecules of two novel β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium
scientific article published on 28 April 2011
Inhibition survey with phenolic compounds against the δ- and η-class carbonic anhydrases from the marine diatom thalassiosira weissflogii and protozoan Plasmodium falciparum
scientific article published on 01 December 2020
Inhibitors of HIV-1 protease: 10 years after
article
Inhibitors of HIV-1 protease: current state of the art 10 years after their introduction. From antiretroviral drugs to antifungal, antibacterial and antitumor agents based on aspartic protease inhibitors
scientific article published on January 2007
Inhibitory activity against carbonic anhydrase IX and XII as a candidate selection criterion in the development of new anticancer agents
scientific article published on 01 December 2020
Inhibitory effects and structural insights for a novel series of coumarin-based compounds that selectively target human CA IX and CA XII carbonic anhydrases
scientific article published on 23 November 2017
Inhibitory effects of benzimidazole containing new phenolic Mannich bases on human carbonic anhydrase isoforms hCA I and II
scientific article published on 17 March 2016
Inhibitory effects of isatin Mannich bases on carbonic anhydrases, acetylcholinesterase, and butyrylcholinesterase
scientific article published on 01 March 2016
Insights into the binding mode of sulphamates and sulphamides to hCA II: crystallographic studies and binding free energy calculations
scientific article published in December 2017
Insights into the effect of elaborating coumarin-based aryl enaminones with sulfonamide or carboxylic acid functionality on carbonic anhydrase inhibitory potency and selectivity
scientific article published in 2022
Insights into the role of reactive sulfhydryl groups of Carbonic Anhydrase III and VII during oxidative damage
scientific article published on 21 October 2016
Intact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX.
scientific article published on 25 October 2009
Integrated approach using protein and ligand information to analyze selectivity- and affinity-determining features of carbonic anhydrase isozymes
scientific article published on 01 August 2006
Interaction Studies between Carbonic Anhydrase and a Sulfonamide Inhibitor by Experimental and Theoretical Approaches
Interaction of anions with a newly characterized alpha carbonic anhydrase from Halomonas sp
scientific article published on 03 November 2015
Interaction of carbonic anhydrase isozymes I, II, and IX with some pyridine and phenol hydrazinecarbothioamide derivatives
scientific article published on 13 October 2015
Interfering with pH regulation in tumours as a therapeutic strategy
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scientific article published on September 16, 2011
Intermolecular amination of allylic and benzylic alcohols leads to effective inhibitions of acetylcholinesterase enzyme and carbonic anhydrase I and II isoenzymes
scientific article published on 05 July 2018
Intracellular binding/unbinding kinetics of approved drugs to carbonic anhydrase II observed by in-cell NMR
scientific article published on 21 September 2020
Investigating the antiplasmodial activity of primary sulfonamide compounds identified in open source malaria data
scientific article (publication date: 13 January 2017)
Investigation of arenesulfonyl-2-imidazolidinones as potent carbonic anhydrase inhibitors
scientific article published on 25 March 2014
Investigation of inhibitory properties of some hydrazone compounds on hCA I, hCA II and AChE enzymes
scientific article published on 04 February 2019
Investigation of pesticides on honey bee carbonic anhydrase inhibition
scientific article published on 01 December 2020
Investigation of piperazines as human carbonic anhydrase I, II, IV and VII activators
scientific article published in December 2018
Investigation of the inhibitory properties of some phenolic standards and bee products against human carbonic anhydrase I and II.
scientific article published on 25 August 2016
Investigations of the esterase, phosphatase, and sulfatase activities of the cytosolic mammalian carbonic anhydrase isoforms I, II, and XIII with 4-nitrophenyl esters as substrates
scientific article
In Vivo Evaluation of Selective Carbonic Anhydrase Inhibitors as Potential Anticonvulsant Agents
scientific article published on 24 February 2016
Iodine-mediated one-pot intramolecular decarboxylation domino reaction for accessing functionalised 2-(1,3,4-oxadiazol-2-yl)anilines with carbonic anhydrase inhibitory action
scientific article published in December 2018
Iodoquinazolinones bearing benzenesulfonamide as human carbonic anhydrase I, II, IX and XII inhibitors: Synthesis, biological evaluation and radiosensitizing activity
scientific article published on 16 May 2020
Isatin analogs as novel inhibitors of Candida spp. β-carbonic anhydrase enzymes.
scientific article published on 27 February 2016
Isatin-derived antibacterial and antifungal compounds and their transition metal complexes
scientific article published in October 2004
Isatin-pyrazole benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase isoforms IX and XII.
scientific article
Isatin: a privileged scaffold for the design of carbonic anhydrase inhibitors.
scientific article published on 24 October 2016
Isoform-selective inhibitory profile of 2-imidazoline-substituted benzene sulfonamides against a panel of human carbonic anhydrases
scientific article published on 10 May 2016
Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors
scientific article
Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111
scientific article published on 11 January 2016
Kinetic and anion inhibition studies of a β-carbonic anhydrase (FbiCA 1) from the C4 plant Flaveria bidentis
scientific article published on 30 January 2013
Kinetic and docking studies of cytosolic/tumor-associated carbonic anhydrase isozymes I, II and IX with some hydroxylic compounds
scientific article published on 4 December 2015
Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site
article
Kinetic and in silico analysis of thiazolidin-based inhibitors of α-carbonic anhydrase isoenzymes
scientific article published on 23 November 2012
Kinetic characterization of 4,4′-biphenylsulfonamides as selective non-zinc binding MMP inhibitors
Kinetic properties and affinities for sulfonamide inhibitors of an α-carbonic anhydrase (CruCA4) involved in coral biomineralization in the Mediterranean red coral Corallium rubrum
scientific article published on 3 May 2017
Lansoprazole and carbonic anhydrase IX inhibitors sinergize against human melanoma cells.
scientific article published on 3 May 2016
Lead Development of Thiazolylsulfonamides with Carbonic Anhydrase Inhibitory Action
scientific article published on 8 March 2017
Legionella pneumophila Carbonic Anhydrases: Underexplored Antibacterial Drug Targets
scientific article
Leishmania infantum arginase: biochemical characterization and inhibition by naturally occurring phenolic substances.
scientific article
Lipoyl-Homotaurine Derivative (ADM_12) Reverts Oxaliplatin-Induced Neuropathy and Reduces Cancer Cells Malignancy by Inhibiting Carbonic Anhydrase IX (CAIX).
scientific article
Looking toward the Rim of the Active Site Cavity of Druggable Human Carbonic Anhydrase Isoforms
scientific article published on 04 March 2020
Lucky Switcheroo: Dramatic Potency and Selectivity Improvement of Imidazoline Inhibitors of Human Carbonic Anhydrase VII.
scientific article published on 15 September 2017
Malarial parasite carbonic anhydrase and its inhibitors
scientific article
Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates
scientific article
Membrane-bound carbonic anhydrases in osteoclasts
scientific article published on 22 December 2006
Metabolism and microenvironment in cancer plasticity.
scientific article published on 15 February 2016
Metal based isatin-derived sulfonamides: their synthesis, characterization, coordination behavior and biological activity
scientific article published in June 2009
Metal binding and antibacterial activity of ciprofloxacin complexes
scientific article published in June 2005
Metal binding functions in the design of carbonic anhydrase inhibitors
scientific article published on January 2007
Metal-Based Antibacterial and Antifungal Agents: Synthesis, Characterization, and In Vitro Biological Evaluation of Co(II), Cu(II), Ni(II), and Zn(II) Complexes With Amino Acid-Derived Compounds
scientific article published on 20 December 2006
Metalloantibiotics: synthesis and antibacterial activity of cobalt(II), copper(II), nickel(II) and zinc(II) complexes of kefzol
scientific article
Metalloantibiotics: synthesis, characterization and in-vitro antibacterial studies on cobalt (II), copper (II), nickel (II) and zinc (II) complexes with cloxacillin
scientific article published in August 2006
Metallocene-Based Inhibitors of Cancer-Associated Carbonic Anhydrase Enzymes IX and XII
scientific article published on 22 May 2012
Metalloenzyme inhibitors for the treatment of Gram-negative bacterial infections: a patent review (2009 – 2012)
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scientific article published on 04 March 2013
Metronidazole-coumarin conjugates and 3-cyano-7-hydroxy-coumarin act as isoform-selective carbonic anhydrase inhibitors
scientific article published on 03 February 2012
Microbial enzyme: applications in industry and in bioremediation
scientific article published on 5 January 2012
Microwave assisted synthesis of novel acridine-acetazolamide conjugates and investigation of their inhibition effects on human carbonic anhydrase isoforms hCA I, II, IV and VII.
scientific article published on 30 May 2016
Microwave assisted synthesis of novel tetrazole/sulfonamide derivatives based on octahydroacridine, xanthene and chromene skeletons as inhibitors of the carbonic anhydrases isoforms I, II, IV and VII.
scientific article published on 12 November 2016
Microwave-assisted extraction, HPLC analysis, and inhibitory effects on carbonic anhydrase I, II, VA, and VII isoforms of 14 blueberry Italian cultivars.
scientific article published on 10 August 2016
Microwave-assisted synthesis and bioevaluation of new sulfonamides.
scientific article published on December 2017
Modification of carbonic anhydrase II with acetaldehyde, the first metabolite of ethanol, leads to decreased enzyme activity.
scientific article
Modulation of carbonic anhydrase 9 (CA9) in human brain cancer
scientific article published on January 2010
Modulation of carbonic anhydrase activity and its applications in therapy
Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target
scientific article published on 28 March 2012
Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate
scientific journal article
Molecular modeling study for the binding of zonisamide and topiramate to the human mitochondrial carbonic anhydrase isoform VA.
scientific article published on 30 March 2007
Mono- and di-halogenated histamine, histidine and carnosine derivatives are potent carbonic anhydrase I, II, VII, XII and XIV activators
scientific article published on 10 July 2014
Mono- and di-thiocarbamate inhibition studies of the δ-carbonic anhydrase TweCAδ from the marine diatom Thalassiosira weissflogii.
scientific article
Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV
scientific article published on 17 May 2012
Monoclonal antibodies raised against 167-180 aa sequence of human carbonic anhydrase XII inhibit its enzymatic activity.
scientific article
Monothiocarbamates Strongly Inhibit Carbonic Anhydrases in Vitro and Possess Intraocular Pressure Lowering Activity in an Animal Model of Glaucoma
scientific article published on 2 June 2016
More effective dithiocarbamate derivatives inhibiting carbonic anhydrases, generated by QSAR and computational design
scientific article published in November 2012
Multicomponent chemistry in the synthesis of carbonic anhydrase inhibitors
scientific article
Multimeric xanthates as carbonic anhydrase inhibitors
scientific article
Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?
scientific article published on 18 May 2012
Multivalent Carbonic Anhydrases Inhibitors
scientific article published on 28 October 2019
Muscarinic acetylcholine receptors as therapeutic targets for obesity
scientific article published on 01 September 2008
Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors
scientific article published on 22 June 2010
Mutation of active site residues Asn67 to Ile, Gln92 to Val and Leu204 to Ser in human carbonic anhydrase II: influences on the catalytic activity and affinity for inhibitors
scientific article published on 16 February 2012
Mycobacterial carbonic anhydrase inhibition with phenolic acids and esters: kinetic and computational investigations
scientific article published on 17 August 2016
Mycobacterium tuberculosis β-Carbonic Anhydrases: Novel Targets for Developing Antituberculosis Drugs
scientific article published on 17 October 2019
N-Acylbenzenesulfonamide Dihydro-1,3,4-oxadiazole Hybrids: Seeking Selectivity toward Carbonic Anhydrase Isoforms.
scientific article
N-Acylsulfonamides strongly inhibit human carbonic anhydrase isoenzymes I and II
scientific article published on 20 March 2015
N-Hydroxyurea—A versatile zinc binding function in the design of metalloenzyme inhibitors
scientific article published on 12 June 2006
N-Nitrosulfonamides as Carbonic Anhydrase Inhibitors: A Promising Chemotype for Targeting Chagas Disease and Leishmaniasis
scientific article published on 27 November 2018
N-Nitrosulfonamides: A new chemotype for carbonic anhydrase inhibition
scientific article published on 30 May 2016
N-Substituted and ring opened saccharin derivatives selectively inhibit transmembrane, tumor-associated carbonic anhydrases IX and XII.
scientific article published on 7 April 2017
N-aryl-N'-ureido-O-sulfamates as potent and selective inhibitors of hCA VB over hCA VA: Deciphering the binding mode of new potential agents in mitochondrial dysfunctions
scientific article published on 04 May 2020
N-aryl-N'-ureido-O-sulfamates: Potent and selective inhibitors of the human Carbonic Anhydrase VII isoform with neuropathic pain relieving properties
scientific article published on 06 June 2019
N-glycosyl-N-hydroxysulfamides as potent inhibitors of Brucella suis carbonic anhydrases
scientific article published on 20 March 2015
N-β-glycosyl sulfamides are selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII
scientific article published on 16 June 2011
NO-releasing esters show carbonic anhydrase inhibitory action against human isoforms I and II
scientific article published on 08 April 2010
Nanoemulsions of sulfonamide carbonic anhydrase inhibitors strongly inhibit the growth of Trypanosoma cruzi
scientific article published in December 2018
Nanoparticles for controlled release of anti-biofilm agents WO2014130994 (A1): a patent evaluation
scientific article published on 01 June 2015
Nanoscale Ion Emitters in Native Mass Spectrometry for Measuring Ligand-Protein Binding Affinities
scientific article published on 14 January 2019
Nanoscale enzyme inhibitors: fullerenes inhibit carbonic anhydrase by occluding the active site entrance
scientific article published on 15 March 2010
Native mass spectrometry of human carbonic anhydrase I and its inhibitor complexes
scientific article published on 14 September 2020
Natural Polyphenols Selectively Inhibit β-Carbonic Anhydrase from the Dandruff-Producing Fungus Malassezia globosa: Activity and Modeling Studies.
scientific article published on 25 March 2018
Natural extracellular nanovesicles and photodynamic molecules: is there a future for drug delivery?
scientific article published in December 2017
Natural product coumarins that inhibit human carbonic anhydrases
scientific article
Natural product hybrid and its superacid synthesized analogues: dodoneine and its derivatives show selective inhibition of carbonic anhydrase isoforms I, III, XIII and XIV.
scientific article published on 23 April 2013
Natural product polyamines that inhibit human carbonic anhydrases.
scientific article published on 5 August 2014
Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases
scientific article
Natural products in drug discovery: advances and opportunities
scientific article
New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII
scientific article published on 30 May 2015
New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII
scientific article published on 13 February 2020
New advances in HIV entry inhibitors development
scientific article
New amide derivatives of Probenecid as selective inhibitors of carbonic anhydrase IX and XII: Biological evaluation and molecular modelling studies
scientific article published on 14 May 2015
New anthranilic acid-incorporating N-benzenesulfonamidophthalimides as potent inhibitors of carbonic anhydrases I, II, IX, and XII: Synthesis, in vitro testing, and in silico assessment
scientific article published on 01 August 2019
New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors
scientific article published on 16 January 2018
New approach of delivering cytotoxic drugs towards CAIX expressing cells: A concept of dual-target drugs
scientific article published on 19 October 2016
New approaches to the synthesis of sildenafil analogues and their enzyme inhibitory activity
scientific article published on 21 February 2015
New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno[1,2-b]pyridin-5-ones
scientific article published on 08 September 2018
New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II
scientific article published on 06 February 2012
New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation
scientific article published on 18 June 2020
New hydroxypyrimidinone-containing sulfonamides as carbonic anhydrase inhibitors also acting as MMP inhibitors.
scientific article published on 28 April 2010
New light on bacterial carbonic anhydrases phylogeny based on the analysis of signal peptide sequences.
scientific article published on 28 June 2016
New macrocyclic amines showing activity as HIV entry inhibitors against wild type and multi-drug resistant viruses
scientific article published on 22 May 2009
New natural product carbonic anhydrase inhibitors incorporating phenol moieties
scientific article published on 20 October 2015
New phenolic Mannich bases with piperazines and their bioactivities
scientific article published on 07 June 2019
New pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors
scientific article published on 10 April 2015
New selective carbonic anhydrase IX inhibitors: synthesis and pharmacological evaluation of diarylpyrazole-benzenesulfonamides.
scientific article
New series of sulfonamides containing amino acid moiety act as effective and selective inhibitors of tumor-associated carbonic anhydrase XII.
scientific article
New strategies for targeting the hypoxic tumour microenvironment in breast cancer
scientific article published on 12 October 2012
New sulfonamides containing organometallic-acylhydrazones: synthesis, characterisation and biological evaluation as inhibitors of human carbonic anhydrases
scientific article published on 01 December 2019
New superacid synthesized (fluorinated) tertiary benzenesulfonamides acting as selective hCA IX inhibitors: toward a new mode of carbonic anhydrase inhibition by sulfonamides
scientific article
New thiopyrimidine-benzenesulfonamide conjugates as selective carbonic anhydrase II inhibitors: synthesis, in vitro biological evaluation, and molecular docking studies
scientific article published on 22 January 2020
New zinc binding motifs in the design of selective carbonic anhydrase inhibitors.
scientific article published on August 2006
Ninhydrins inhibit carbonic anhydrases directly binding to the metal ion
scientific article published on 05 October 2020
Nitric oxide donors and selective carbonic anhydrase inhibitors: a dual pharmacological approach for the treatment of glaucoma, cancer and osteoporosis.
scientific article published on 31 March 2015
Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma
scientific article
Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes
scientific article published on 01 December 2018
Non-Classical Inhibition of Carbonic Anhydrase
scientific article
Non-peptidic chemokine receptors antagonists as emerging anti-HIV agents
scientific article
Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors
scientific article
Nonaromatic Sulfonamide Group as an Ideal Anchor for Potent Human Carbonic Anhydrase Inhibitors: Role of Hydrogen-Bonding Networks in Ligand Binding and Drug Design
scientific article published on 01 August 2002
Nontargeted Identification of Plasma Proteins O-, N-, and S-Transmethylated by O-Methyl Organophosphates
scientific article published on 17 November 2020
Novel 2-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)-1-(1,3,5-triazin-2-ylamino)guanidine derivatives: Inhibition of human carbonic anhydrase cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII, anticancer a
scientific article published on 4 November 2017
Novel 2-indolinones containing a sulfonamide moiety as selective inhibitors of candida β-carbonic anhydrase enzyme
scientific article published on 01 December 2019
Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies
scientific article published on 01 December 2019
Novel 3-substituted coumarins as selective human carbonic anhydrase IX and XII inhibitors: Synthesis, biological and molecular dynamics analysis
scientific article published on 01 October 2020
Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies.
scientific article published in August 2017
Novel 6- and 7-Substituted Coumarins with Inhibitory Action against Lipoxygenase and Tumor-Associated Carbonic Anhydrase IX.
scientific article published on 12 January 2018
Novel 8-Substituted Coumarins That Selectively Inhibit Human Carbonic Anhydrase IX and XII
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scientific article published on 10 March 2019
Novel Diamide-Based Benzenesulfonamides as Selective Carbonic Anhydrase IX Inhibitors Endowed with Antitumor Activity: Synthesis, Biological Evaluation and In Silico Insights.
scientific article published on 20 May 2019
Novel Indole-Based Hydrazones as Potent Inhibitors of the α-class Carbonic Anhydrase from Pathogenic Bacterium Vibrio cholerae
scientific article published on 29 April 2020
Novel Insights on Human Carbonic Anhydrase Inhibitors Based on Coumalic Acid: Design, Synthesis, Molecular Modeling Investigation, and Biological Studies
scientific article published in 2022
Novel Re(I) tricarbonyl coordination compounds based on 2-pyridyl-1,2,3-triazole derivatives bearing a 4-amino-substituted benzenesulfonamide arm: synthesis, crystal structure, computational studies and inhibitory activity against carbonic anhydrase
scientific article published on 01 December 2019
Novel Sulfamide-Containing Compounds as Selective Carbonic Anhydrase I Inhibitors.
scientific article
Novel approaches for designing drugs that interfere with pH regulation
scientific article published on 25 January 2019
Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and in vitro biological evaluation
scientific article published on 01 December 2020
Novel carbonic anhydrase IX-targeted therapy enhances the anti-tumour effects of cisplatin in small cell lung cancer.
scientific article
Novel coumarins and 2-thioxo-coumarins as inhibitors of the tumor-associated carbonic anhydrases IX and XII
article
Novel coumarins and benzocoumarins acting as isoform-selective inhibitors against the tumor-associated carbonic anhydrase IX.
scientific article published on 14 March 2013
Novel hydrazido benzenesulfonamides-isatin conjugates: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies
scientific article published on 24 July 2018
Novel indolin-2-one-based sulfonamides as carbonic anhydrase inhibitors: Synthesis, in vitro biological evaluation against carbonic anhydrases isoforms I, II, IV and VII and molecular docking studies.
scientific article published on 11 January 2017
Novel insights on saccharin- and acesulfame-based carbonic anhydrase inhibitors: design, synthesis, modelling investigations and biological activity evaluation
scientific article published on 01 December 2020
Novel organometallic cationic ruthenium(II) pentamethylcyclopentadienyl benzenesulfonamide complexes targeted to inhibit carbonic anhydrase
scientific article
Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors
scientific article
Novel sulfamides as potential carbonic anhydrase isoenzymes inhibitors
scientific article published on 22 January 2013
Novel sulfonamide bearing coumarin scaffolds as selective inhibitors of tumor associated carbonic anhydrase isoforms IX and XII.
scientific article published on 26 April 2016
Novel sulfonamide incorporating piperazine, aminoalcohol and 1,3,5-triazine structural motifs with carbonic anhydrase I, II and IX inhibitory action.
scientific article published on 3 January 2018
Novel sulfonamide-containing 2-indolinones that selectively inhibit tumor-associated alpha carbonic anhydrases
scientific article published on 15 May 2017
Novel sulfonamides bearing pyrrole and pyrrolopyrimidine moieties as carbonic anhydrase inhibitors: Synthesis, cytotoxic activity and molecular modeling
scientific article published on 19 September 2014
Novel sulfonamides incorporating 1,3,5-triazine and amino acid structural motifs as inhibitors of the physiological carbonic anhydrase isozymes I, II and IV and tumor-associated isozyme IX
scientific article published on 16 August 2018
Novel sulphonamides incorporating triazene moieties show powerful carbonic anhydrase I and II inhibitory properties
scientific article published on 01 December 2020
Novel synthesized SLC-0111 thiazole and thiadiazole analogues: Determination of their carbonic anhydrase inhibitory activity and molecular modeling studies
scientific article published on 03 April 2019
Novel therapies for glaucoma: a patent review 2007 – 2011
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scientific article published on December 23, 2011
Novel thiazolidinone-containing compounds, without the well-known sulphonamide zinc-binding group acting as human carbonic anhydrase IX inhibitors
scholarly article by Özlen Güzel-Akdemir et al published December 2018 in Journal of Enzyme Inhibition and Medicinal Chemistry
Novel use of chemical shift in NMR as molecular descriptor: a first report on modeling carbonic anhydrase inhibitory activity and related parameters
scientific article
Open saccharin-based secondary sulfonamides as potent and selective inhibitors of cancer-related carbonic anhydrase IX and XII isoforms.
scientific article
Orbital Symmetry in QSAR: Some Schiff's Base Inhibitors of Carbonic Anhydrase
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scientific article published on January 1, 2001
Organometallic-based antibacterial and antifungal compounds: transition metal complexes of 1,1'-diacetylferrocene-derived thiocarbohydrazone, carbohydrazone, thiosemicarbazone and semicarbazone
scientific article published in February 2005
Organoruthenium(II) complexes of acetazolamide potently inhibit human carbonic anhydrase isoforms I, II, IX and XII
scientific article published on 01 December 2019
Out of the active site binding pocket for carbonic anhydrase inhibitors
scientific article
Overexpression of the transmembrane carbonic anhydrase isoforms IX and XII in the inflamed synovium
scientific article published on 15 August 2016
Oxidation of cyanobenzocycloheptatrienes: Synthesis, photooxygenation reaction and carbonic anhydrase isoenzymes inhibition properties of some new benzotropone derivatives
scientific article published on 02 May 2014
Oxovanadium(IV) complexes of hydrazides: potential antifungal agents
scientific article published on 01 February 2006
PEGylated Bis-Sulfonamide Carbonic Anhydrase Inhibitors Can Efficiently Control the Growth of Several Carbonic Anhydrase IX-Expressing Carcinomas
scientific article published on 10 May 2016
PET Imaging of Carbonic Anhydrase IX Expression of HT-29 Tumor Xenograft Mice with (68)Ga-Labeled Benzenesulfonamides.
scientific article
Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis
scientific article published on 18 April 2019
Paraoxon, 4-nitrophenyl phosphate and acetate are substrates of α- but not of β-, γ- and ζ-carbonic anhydrases
scientific article published on 26 August 2010
Peptidomimetics as protein arginine deiminase 4 (PAD4) inhibitors
scientific article published on 08 September 2014
Perfluoroalkyl Substances of Significant Environmental Concern Can Strongly Inhibit Human Carbonic Anhydrase Isozymes
scientific article published on 04 March 2020
Personalized Treatment Response Assessment for Rare Childhood Tumors Using Microcalorimetry-Exemplified by Use of Carbonic Anhydrase IX and Aquaporin 1 Inhibitors
scientific article published on 09 October 2019
Phaeodactylum tricornutum as a model organism for testing the membrane penetrability of sulphonamide carbonic anhydrase inhibitors
article
Pharmacological Inhibition of CA-IX Impairs Tumor Cell Proliferation, Migration and Invasiveness
scientific article published on 23 April 2020
Pharmacological inhibition of carbonic anhydrase XII interferes with cell proliferation and induces cell apoptosis in T-cell lymphomas
scientific article
Phenols and Polyphenols as Carbonic Anhydrase Inhibitors
scientific article
Phenyl(thio)phosphon(amid)ate Benzenesulfonamides as Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in a Mouse Model of Oxaliplatin-Induced Neuropathy
scientific article published on 04 May 2020
Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II
scientific article published on 30 July 2011
Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I
scientific article
Phosphate Chemical Probes Designed for Location Specific Inhibition of Intracellular Carbonic Anhydrases
scientific article published on 01 September 2015
Phosphodiesterase 5 inhibitors--drug design and differentiation based on selectivity, pharmacokinetic and efficacy profiles
scientific article published on January 2006
Phosphonamidates are the first phosphorus-based zinc binding motif to show inhibition of β-class carbonic anhydrases from bacteria, fungi, and protozoa
scientific article published on 01 December 2020
Phosphorus vs sulphur: discovery of benzenephosphonamidates as new versatile sulfonamide-mimic chemotypes acting as carbonic anhydrase inhibitors
scientific article published on 14 December 2018
Phosphorylation of carbonic anhydrase IX controls its ability to mediate extracellular acidification in hypoxic tumors.
scientific article
Plasmatic carbonic anhydrase IX as a diagnostic marker for clear cell renal cell carcinoma.
scientific article published in December 2018
Plasmatic exosomes from prostate cancer patients show increased carbonic anhydrase IX expression and activity and low pH
scientific article published on 01 December 2020
Poly(amidoamine) Dendrimers with Carbonic Anhydrase Inhibitory Activity and Antiglaucoma Action
scientific article published on 15 April 2015
Poly(amidoamine) dendrimers show carbonic anhydrase inhibitory activity against α-, β-, γ- and η-class enzymes
scientific article published on 08 October 2015
Polyamines and α-Carbonic Anhydrases
scientific article
Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule
scientific article
Polypharmacology of epacadostat: a potent and selective inhibitor of the tumor associated carbonic anhydrases IX and XII
scientific article published on 01 May 2019
Polypharmacology of sulfonamides: pazopanib, a multitargeted receptor tyrosine kinase inhibitor in clinical use, potently inhibits several mammalian carbonic anhydrases.
scientific article published on 26 June 2012
Post-translational modifications in tumor-associated carbonic anhydrases
Potent and Selective Carboxylic Acid Inhibitors of Tumor-Associated Carbonic Anhydrases IX and XII.
scientific article published on 22 December 2017
Predictive flip regression: a technique for QSAR of derivatives of symmetric molecules
scientific article published in September 2005
Preface
Preface
Preparation, carbonic anhydrase enzyme inhibition and antioxidant activity of novel 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives incorporating mono or dipeptide moiety
scientific article published on 01 December 2020
Primary anetoderma and HIV infection: a case report
scientific article published on 01 February 2006
Primary mono- and bis-sulfonamides obtained via regiospecific sulfochlorination of N-arylpyrazoles: inhibition profile against a panel of human carbonic anhydrases.
scientific article
Privileged scaffolds in medicinal chemistry: Studies on pyrazolo[1,5-a]pyrimidines on sulfonamide containing Carbonic Anhydrase inhibitors
scientific article published in 2021
Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides.
scientific article published on 28 April 2017
Probing the 'bipolar' nature of the carbonic anhydrase active site: aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoforms
scientific article published on 25 June 2015
Production and covalent immobilisation of the recombinant bacterial carbonic anhydrase (SspCA) onto magnetic nanoparticles.
scientific article published in December 2017
Prognostic value of CAIX expression in oral squamous cell carcinoma: a systematic review and meta-analysis
scientific article published on 01 December 2020
Progress in the development of human carbonic anhydrase inhibitors and their pharmacological applications: Where are we today?
scientific article published on 21 July 2020
Progress in the field of GPIIb/IIIa antagonists
scientific article published in April 2004
Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors
scientific article
Prostaglandin receptor agonists as antiglaucoma agents (a patent review 2013 - 2018)
scientific article published on 04 September 2019
Prostate cancer cells and exosomes in acidic condition show increased carbonic anhydrase IX expression and activity
scientific article published on 01 December 2019
Protease inhibitors of the sulfonamide type: anticancer, antiinflammatory, and antiviral agents
scientific article
Protease inhibitors targeting the main protease and papain-like protease of coronaviruses
scientific article published on 27 November 2020
Protease inhibitors: synthesis of bacterial collagenase and matrix metalloproteinase inhibitors incorporating arylsulfonylureido and 5-dibenzo-suberenyl/suberyl moieties
scientific article published in May 2003
Protease inhibitors: synthesis of bacterial collagenase and matrix metalloproteinase inhibitors incorporating succinyl hydroxamate and iminodiacetic acid hydroxamate moieties
scientific article published in June 2003
Protease inhibitors: synthesis of matrix metalloproteinase and bacterial collagenase inhibitors incorporating 5-amino-2-mercapto-1,3,4-thiadiazole zinc binding functions
scientific article published in October 2002
Protein tyrosine kinase inhibitors as anticancer agents
article published in 2004
Protein–Protein Interactions: Inhibition of Mammalian Carbonic Anhydrases I–XV by the Murine Inhibitor of Carbonic Anhydrase and Other Members of the Transferrin Family
scientific article published on 18 May 2012
Protonography and anion inhibition profile of the α-carbonic anhydrase (CruCA4) identified in the Mediterranean red coral Corallium rubrum
scientific article published on 5 December 2017
Protonography, a new technique for the analysis of carbonic anhydrase activity.
scientific article
Protonography, a powerful tool for analyzing the activity and the oligomeric state of the γ-carbonic anhydrase identified in the genome of Porphyromonas gingivalis.
scientific article published on 11 April 2015
Protonography, a technique applicable for the analysis of η-carbonic anhydrase activity
scientific article published on 13 February 2015
Pseudomonas aeruginosa β-carbonic anhydrase, psCA1, is required for calcium deposition and contributes to virulence
scientific article published on 27 September 2019
Psychoactive substances belonging to the amphetamine class potently activate brain carbonic anhydrase isoforms VA, VB, VII, and XII.
scientific article published in December 2017
Pteridine-sulfonamide conjugates as dual inhibitors of carbonic anhydrases and dihydrofolate reductase with potential antitumor activity
scientific article published on 2 June 2010
Purification and characterization of carbonic anhydrase from sheep kidney and effects of sulfonamides on enzyme activity
scientific article
Purification and inhibition studies with anions and sulfonamides of an α-carbonic anhydrase from the Antarctic seal Leptonychotes weddellii
scientific article published on 13 February 2011
Putative anion transporter-1 (Pat-1, Slc26a6) contributes to intracellular pH regulation during H+-dipeptide transport in duodenal villous epithelium
scientific journal article
Pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors with antitumor activity.
scientific article published on 27 March 2014
Pyrazolylbenzo[d]imidazoles as new potent and selective inhibitors of carbonic anhydrase isoforms hCA IX and XII
scientific article published on 28 April 2016
Pyridazinone substituted benzenesulfonamides as potent carbonic anhydrase inhibitors
scientific article published on 07 December 2015
Pyridazinone-substituted benzenesulfonamides display potent inhibition of membrane-bound human carbonic anhydrase IX and promising antiproliferative activity against cancer cell lines
scientific article published on 15 February 2019
Pyridinium derivatives of 3-aminobenzenesulfonamide are nanomolar-potent inhibitors of tumor-expressed carbonic anhydrase isozymes CA IX and CA XII
scientific article published on 26 August 2020
Pyridinium derivatives of histamine are potent activators of cytosolic carbonic anhydrase isoforms I, II and VII
scientific article published on 02 March 2011
Pyrrolo and pyrrolopyrimidine sulfonamides act as cytotoxic agents in hypoxia via inhibition of transmembrane carbonic anhydrases
scientific article published on 30 December 2019
QSAR studies for the inhibition of the transmembrane carbonic anhydrase isozyme XIV with sulfonamides using PRECLAV software
scientific article published in April 2009
QSAR studies for the inhibition of the transmembrane isozymes XII and XIV of human carbonic anhydrase with a series of sulfonamides
scientific article published on 8 June 2007
QSAR studies of sulfamate and sulfamide inhibitors targeting human carbonic anhydrase isozymes I, II, IX and XII.
scientific article published on 10 November 2012
QSAR studies on benzene sulfonamide carbonic anhydrase inhibitors: need of hydrophobic parameter for topological modeling of binding constants of sulfonamides to human CA-II.
scientific article
QSAR studies on benzopyran potassium channel activators
scientific article published on 3 February 2006
QSAR studies on the activation of the human carbonic anhydrase cytosolic isoforms I and II and secretory isozyme VI with amino acids and amines
scientific article published on 25 July 2007
QSAR study on CA inhibitory activity of disulfonamides: effect of halogen substitution
scientific article published on 01 May 2004
QSAR study on benzenesulphonamide carbonic anhydrase inhibitors: topological approach using Balaban index
scientific article published in February 2004
QSAR study on carbonic anhydrase inhibitors: aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl moieties, with topical activity as antiglaucoma agents
scientific article published in July 2004
QSAR study on carbonic anhydrase inhibitors: water-soluble sulfonamides incorporating beta-alanyl moieties, possessing long lasting-intra ocular pressure lowering properties--a molecular connectivity approach
scientific article published on 14 June 2005
QSAR study on pK(a) vis-à-vis physiological activity of sulfonamides: a dominating role of surface tension (inverse steric parameter).
scientific article published in January 2005
QSAR study on para-substituted aromatic sulfonamides as carbonic anhydrase II inhibitors using topological information indices
scientific article published on 5 October 2005
QSAR study on topically acting sulfonamides incorporating GABA moieties: a molecular connectivity approach
scientific article published on 2 February 2006
QSAR study using topological indices for inhibition of carbonic anhydrase II by sulfanilamides and Schiff bases
scientific article published in January 2004
QSARs on human carbonic anhydrase VA and VB inhibitors of some new not yet synthesized, substituted aromatic/heterocyclic sulphonamides as anti-obesity agent
scientific article published on 08 September 2011
Quantitative analysis of carbonic anhydrase IX mRNA in human non-small cell lung cancer
scientific article published on 28 February 2006
Quantitative assessment of specific carbonic anhydrase inhibitors effect on hypoxic cells using electrical impedance assays
scientific article published in December 2017
Quantitative structure-activity relationship study on sulfanilamide schiff's bases: carbonic anhydrase (CA) inhibitors
scientific article published in December 2003
Quantum theoretic QSAR of benzene derivatives: some enzyme inhibitors
scientific article published in June 2004
Quinazoline-sulfonamides with potent inhibitory activity against the α-carbonic anhydrase from Vibrio cholerae
scientific article published on 21 August 2014
Radiotracers for positron emission tomography (PET) targeting tumour-associated carbonic anhydrase isoforms
scientific article published on 25 November 2020
Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug
scientific article
Recent advances in structural studies of the carbonic anhydrase family: the crystal structure of human CA IX and CA XIII.
scientific article published on January 2010
Recent advances in the discovery of zinc-binding motifs for the development of carbonic anhydrase inhibitors.
scientific article
Recent developments in targeting carbonic anhydrase IX for cancer therapeutics
scientific article
Recent developments of carbonic anhydrase inhibitors as potential anticancer drugs
scientific article published on 19 March 2008
Recombinant thermoactive phosphoenolpyruvate carboxylase (PEPC) from Thermosynechococcus elongatus and its coupling with mesophilic/thermophilic bacterial carbonic anhydrases (CAs) for the conversion of CO2 to oxaloacetate.
scientific article published on 8 December 2015
Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase
scientific article published in December 2021
Reconstitution of carbonic anhydrase activity of the cell-surface-binding protein of vaccinia virus.
scientific article
Redox state and carbonic anhydrase isozyme IX expression in human renal cell carcinoma: biochemical and morphological investigations
scientific article published in June 2004
Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models
scientific article published on 17 August 2016
Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia
scientific article published on 09 May 2019
Resolution of co-eluting isomers of anti-inflammatory drugs conjugated to carbonic anhydrase inhibitors from plasma in liquid chromatography by energy-resolved tandem mass spectrometry
scientific article published in December 2018
Response to Perspectives on the Classical Enzyme Carbonic Anhydrase and the Search for Inhibitors
scientific article published on 08 December 2020
Restoring catalytic activity to the human carbonic anhydrase (CA) related proteins VIII, X and XI affords isoforms with high catalytic efficiency and susceptibility to anion inhibition.
scientific article published on 9 November 2012
Rethinking the Combination of Proton Exchanger Inhibitors in Cancer Therapy
scientific article published on 23 December 2017
Rho-kinase inhibitors in the management of glaucoma
scientific article published on 01 October 2019
Root effect hemoglobin may have evolved to enhance general tissue oxygen delivery.
scientific article
Rosmarinic acid inhibits some metabolic enzymes including glutathione S-transferase, lactoperoxidase, acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase isoenzymes
scientific article published on 10 February 2016
S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases
scientific article
S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors
scientific article published on 01 December 2020
SLC-0111 enaminone analogs, 3/4-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX
scientific article published on 14 November 2018
Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste
scientific article
Saccharin: a lead compound for structure-based drug design of carbonic anhydrase IX inhibitors.
scientific article
Saccharomyces cerevisiae β-carbonic anhydrase: inhibition and activation studies
scientific article published on January 2010
Salen and tetrahydrosalen derivatives act as effective inhibitors of the tumor-associated carbonic anhydrase XII--a new scaffold for designing isoform-selective inhibitors.
scientific article
Salicylaldoxime derivatives as new leads for the development of carbonic anhydrase inhibitors.
scientific article
Salts of 5-amino-2-sulfonamide-1,3,4-thiadiazole, a structural and analog of acetazolamide, show interesting carbonic anhydrase inhibitory properties, diuretic, and anticonvulsant action
scientific article published on 26 October 2015
Screening of benzenesulfonamide in combination with chemically diverse fragments against carbonic anhydrase by differential scanning fluorimetry
scientific article published on 01 December 2020
Secondary and tertiary sulfonamides: a patent review (2008 – 2012)
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scientific article published on November 14, 2012
Secondary/tertiary benzenesulfonamides with inhibitory action against the cytosolic human carbonic anhydrase isoforms I and II.
scientific article published in March 2012
Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivatives
scientific article published on 01 December 2019
Selection of Carbonic Anhydrase IX Inhibitors from One Million DNA-Encoded Compounds
scientific article
Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency
scientific article
Selective inhibition of carbonic anhydrase IX decreases cell proliferation and induces ceramide-mediated apoptosis in human cancer cells.
scientific article
Selective inhibition of carbonic anhydrase IX over carbonic anhydrase XII in breast cancer cells using benzene sulfonamides: Disconnect between activity and growth inhibition
scientific article published in PLoS ONE
Selective inhibition of carbonic anhydrase-IX by sulphonamide derivatives induces pH and reactive oxygen species-mediated apoptosis in cervical cancer HeLa cells.
scientific article published in December 2018
Selective inhibition of human carbonic anhydrases by novel amide derivatives of probenecid: synthesis, biological evaluation and molecular modelling studies.
scientific article published on 26 June 2014
Selenides bearing benzenesulfonamide show potent inhibition activity against carbonic anhydrases from pathogenic bacteria Vibrio cholerae and Burkholderia pseudomallei
scientific article published on 18 May 2018
Selenolesterase enzyme activity of carbonic anhydrases
scientific article published on 20 March 2020
Selenols: a new class of carbonic anhydrase inhibitors
scientific article published on 01 January 2019
Sequence Analysis, Kinetic Constants, and Anion Inhibition Profile of the Nacrein-Like Protein (CgiNAP2X1) from the Pacific Oyster Magallana gigas (Ex-Crassostrea gigas).
scientific article published on 28 August 2017
Serendipitous fragment-based drug discovery: ketogenic diet metabolites and statins effectively inhibit several carbonic anhydrases.
scientific article published in March 2012
Sildenafil is a strong activator of mammalian carbonic anhydrase isoforms I-XIV.
scientific article published on 17 July 2009
Simple methanesulfonates are hydrolyzed by the sulfatase carbonic anhydrase activity
scientific article published on 06 December 2011
Skewing towards neuroendocrine phenotype in high grade or high stage androgen-responsive primary prostate cancer
scientific article published on 02 April 2005
Small molecule antagonists of chemokine receptors as emerging anti-HIV agents
article
Small-molecule suppression of misfolding of mutated human carbonic anhydrase II linked to marble brain disease.
scientific article published in June 2009
Sources of protons and a role for bicarbonate in inhibitory feedback from horizontal cells to cones in Ambystoma tigrinum retina
scientific article published on 27 June 2016
Special Issue: Sulfonamides.
scientific article published on 29 September 2017
Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation.
scientific article published on 14 June 2011
Sperm from sneaker male squids exhibit chemotactic swarming to CO₂.
scientific article published on 11 April 2013
Spirobisnaphthalenes effectively inhibit carbonic anhydrase
scientific article published on 28 May 2015
Spirocyclic sulfonamides with carbonic anhydrase inhibitory and anti-neuropathic pain activity
scientific article published on 17 August 2019
State of the Art on Carbonic Anhydrase Modulators for Biomedical Purposes
scientific article published on 01 January 2019
Statement of retraction
scientific article published on 29 May 2012
Stereoselective pharmacokinetic and pharmacodynamic analysis of a CNS-active sulphamoylphenyl carbamate derivative
scientific article published on 01 December 2019
Steroids interfere with human carbonic anhydrase activity by using alternative binding mechanisms
scientific article published on 01 December 2018
Structural Basis for the Inhibition of Helicobacter pylori α-Carbonic Anhydrase by Sulfonamides
scientific article published on 26 May 2015
Structural Basis of Nanomolar Inhibition of Tumor-Associated Carbonic Anhydrase IX: X-Ray Crystallographic and Inhibition Study of Lipophilic Inhibitors with Acetazolamide Backbone
scientific article published on 21 October 2020
Structural Insights on Carbonic Anhydrase Inhibitory Action, Isoform Selectivity, and Potency of Sulfonamides and Coumarins Incorporating Arylsulfonylureido Groups
Structural Mapping of Anion Inhibitors to β-Carbonic Anhydrase psCA3 from Pseudomonas aeruginosa
scientific article published on 13 September 2018
Structural and biochemical characterization of novel carbonic anhydrases from Phaeodactylum tricornutum
scientific article published on 30 June 2020
Structural and inhibition insights into carbonic anhydrase CDCA1 from the marine diatom Thalassiosira weissflogii
scientific article
Structural basis for the interaction between carbonic anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides
scientific article
Structural effect of phenyl ring compared to thiadiazole based adamantyl-sulfonamides on carbonic anhydrase inhibition
scientific article
Structural insights into carbonic anhydrase IX isoform specificity of carbohydrate-based sulfamates
scientific article
Structural investigations on coumarins leading to chromeno[4,3-c]pyrazol-4-ones and pyrano[4,3-c]pyrazol-4-ones: New scaffolds for the design of the tumor-associated carbonic anhydrase isoforms IX and XII.
scientific article published on 12 January 2018
Structural modulation of the biological activity of gold nanoparticles functionalized with a carbonic anhydrase inhibitor.
scientific article published on 17 May 2013
Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases
scientific article
Structural study of the location of the phenyl tail of benzene sulfonamides and the effect on human carbonic anhydrase inhibition
scientific article
Structure activity study of carbonic anhydrase IX: Selective inhibition with ureido-substituted benzenesulfonamides.
scientific article published on 19 March 2017
Structure and biological properties of first row d-transition metal complexes with N-substituted sulfonamides
scientific article published in April 2008
Structure and function of carbonic anhydrases
scientific article
Structure and inhibition of the CO2-sensing carbonic anhydrase Can2 from the pathogenic fungus Cryptococcus neoformans
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Structure and inhibition studies of a type II beta-carbonic anhydrase psCA3 from Pseudomonas aeruginosa
scientific article
Structure-Activity Relationship for Sulfonamide Inhibition of Helicobacter pylori α-Carbonic Anhydrase
scientific article published on 8 December 2016
Structure-Activity Relationships of Benzenesulfonamide-Based Inhibitors towards Carbonic Anhydrase Isoform Specificity
scientific article published on 18 November 2016
Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation
scientific article published on 22 August 2019
Structure-activity relationships for the interaction of 5,10-dihydroindeno[1,2-b]indole derivatives with human and bovine carbonic anhydrase isoforms I, II, III, IV and VI
scientific article published on 20 December 2011
Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents
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Structure-based drug discovery of carbonic anhydrase inhibitors
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scientific article published on 02 April 2012
Structure-based screening for the discovery of new carbonic anhydrase VII inhibitors
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Study on supramolecular complexing ability vis-à-vis estimation of pKa of substituted sulfonamides: dominating role of Balaban index (J)
scientific article published on 01 September 2005
Substituted benzene sulfonamides incorporating 1,3,5-triazinyl moieties potently inhibit human carbonic anhydrases II, IX and XII
scientific article published on 27 January 2014
Sulfa and trimethoprim-like drugs - antimetabolites acting as carbonic anhydrase, dihydropteroate synthase and dihydrofolate reductase inhibitors
scientific article published on 29 April 2013
Sulfamates and their therapeutic potential
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Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action
scientific article
Sulfapyridine-like benzenesulfonamide derivatives as inhibitors of carbonic anhydrase isoenzymes I, II and VI
scientific article published on 22 December 2011
Sulfenamido-Sulfonamides as Inhibitors of Carbonic Anhydrase Isozymes I, II And IV
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scientific article published on 01 August 1997
Sulfocoumarin-, Coumarin-, 4-Sulfamoylphenyl-Bearing Indazole-3-carboxamide Hybrids: Synthesis and Selective Inhibition of Tumor-Associated Carbonic Anhydrase Isozymes IX and XII.
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Sulfocoumarins (1,2-benzoxathiine-2,2-dioxides): a class of potent and isoform-selective inhibitors of tumor-associated carbonic anhydrases
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Sulfocoumarins as dual inhibitors of human carbonic anhydrase isoforms IX/XII and of human thioredoxin reductase
scientific article published on 01 December 2020
Sulfonamide Inhibition Profile of the β-Carbonic Anhydrase from Malassezia restricta, An Opportunistic Pathogen Triggering Scalp Conditions
scientific article published on 16 January 2020
Sulfonamide Inhibition Studies of a New β-Carbonic Anhydrase from the Pathogenic Protozoan
scientific article published in 2018
Sulfonamide Inhibition Studies of an α-Carbonic Anhydrase from Schistosoma mansoni, a Platyhelminth Parasite Responsible for Schistosomiasis
scientific article published on 07 March 2020
Sulfonamide Inhibition Studies of the β-Class Carbonic Anhydrase CAS3 from the Filamentous Ascomycete Sordaria macrospora
scientific article published on 25 February 2020
Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action
scientific article published on 10 June 2020
Sulfonamide bearing pyrazolylpyrazolines as potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII
scientific article published on 14 June 2015
Sulfonamide carbonic anhydrase inhibitors: Zinc coordination and tail effects influence inhibitory efficacy and selectivity for different isoforms
Sulfonamide derivatives with protease inhibitory action as anticancer, anti-inflammatory and antiviral agents
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Sulfonamide diuretic azosemide as an efficient carbonic anhydrase inhibitor
scientific article published in 2022
Sulfonamide inhibition profile of the γ-carbonic anhydrase identified in the genome of the pathogenic bacterium Burkholderia pseudomallei the etiological agent responsible of melioidosis
scientific article
Sulfonamide inhibition profiles of the β-carbonic anhydrase from the pathogenic bacterium Francisella tularensis responsible of the febrile illness tularemia
scientific article published on 6 May 2017
Sulfonamide inhibition studies of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA
scientific article published on 01 December 2015
Sulfonamide inhibition studies of the β carbonic anhydrase from Drosophila melanogaster.
scientific article published on 9 May 2014
Sulfonamide inhibition studies of the β-carbonic anhydrase from the newly discovered bacterium Enterobacter sp. B13.
scientific article
Sulfonamide inhibition studies of the β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae
scientific article published on 22 January 2016
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea
scientific article published on 11 January 2016
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.
scientific article
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune.
scientific article
Sulfonamide inhibition studies of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis.
scientific article published on 21 November 2013
Sulfonamide inhibition studies of the δ-carbonic anhydrase from the diatom Thalassiosira weissflogii.
scientific article
Sulfonamide inhibition studies of the η-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum
scientific article published on 11 December 2014
Sulfonamide inhibition studies of two β-carbonic anhydrases from the ascomycete fungus Sordaria macrospora, CAS1 and CAS2.
scientific article published in December 2018
Sulfonamide inhibition studies of two β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila
scientific article published on 13 April 2014
Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: the β-class (PgiCAb) versus the γ-class (PgiCA) enzymes.
scientific article published on 7 August 2014
Sulfonamide inhibition study of the β-class carbonic anhydrase from the caries producing pathogen Streptococcus mutans
scientific article published on 17 April 2015
Sulfonamide linked neoglycoconjugates--a new class of inhibitors for cancer-associated carbonic anhydrases
scientific article
Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation
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Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors
scientific article published on 21 November 2019
Sulfonamides and their isosters as carbonic anhydrase inhibitors.
scientific article
Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies
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Sulfonamides incorporating boroxazolidone moieties are potent inhibitors of the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII
scientific article published on 21 March 2011
Sulfonamides incorporating fluorine and 1,3,5-triazine moieties are effective inhibitors of three β-class carbonic anhydrases from Mycobacterium tuberculosis
scientific article published on 24 October 2013
Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII
scientific article published on 11 January 2016
Sulfonamides incorporating piperazine bioisosteres as potent human carbonic anhydrase I, II, IV and IX inhibitors
scientific article published on 20 July 2019
Sulfonamides with Potent Inhibitory Action and Selectivity against the α-Carbonic Anhydrase from Vibrio cholerae.
scientific article published on 23 May 2014
Sulfonamides: a patent review (2008 – 2012)
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scientific article published on June 15, 2012
Sulfonylamido Derivatives of 2-Aminophenoxathiin-10,10-Dioxide and Related Compounds Possess Antifungal Action Due to the Possible Inhibition of Lanosterol-14-α-Demethylase
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scientific article published on July 1, 1998
Sulfur, selenium and tellurium containing amines act as effective carbonic anhydrase activators
scientific article published on 25 March 2019
Sulphonamide inhibition profile of Staphylococcus aureus β-carbonic anhydrase
scientific article published on 01 December 2020
Sulphonamide inhibition studies of the β-carbonic anhydrase from the bacterial pathogen Clostridium perfringens
scientific article published in December 2018
Sulphonamides incorporating 1,3,5-triazine structural motifs show antioxidant, acetylcholinesterase, butyrylcholinesterase, and tyrosinase inhibitory profile
scientific article published on 01 December 2020
Sultam based Carbonic Anhydrase VII inhibitors for the management of neuropathic pain
Superacid synthesis of halogen containing N-substituted-4-aminobenzene sulfonamides: new selective tumor-associated carbonic anhydrase inhibitors
scientific article published on 26 May 2012
Superacid synthesized tertiary benzenesulfonamides and benzofuzed sultams act as selective hCA IX inhibitors: toward understanding a new mode of inhibition by tertiary sulfonamides
scientific article published on 01 November 2013
Supercharging protein ions in native mass spectrometry using theta capillary nanoelectrospray ionization mass spectrometry and cyclic alkylcarbonates.
scientific article published on 12 December 2017
Supported ionic liquid membranes immobilized with carbonic anhydrases for CO 2 transport at high temperatures
Sweet Binders: Carbonic Anhydrase IX in Complex with Sucralose
scientific article published on 10 May 2018
Syntesis of thio- and seleno-acetamides bearing benzenesulfonamide as potent inhibitors of human carbonic anhydrase II and XII
scientific article published on 15 May 2019
Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory properties
scientific article published on 27 June 2016
Synthesis and Biological Evaluation of 4-Sulfamoylphenyl/Sulfocoumarin Carboxamides as Selective Inhibitors of Carbonic Anhydrase Isoforms hCA II, IX, and XII
scientific article published on 22 May 2018
Synthesis and Biological Evaluation of Imidazo[2 ,1-b]Thiazole based Sulfonyl Piperazines as Novel Carbonic Anhydrase II Inhibitors
scientific article published on 31 March 2020
Synthesis and Evaluation of Carbonic Anhydrase Inhibitors with Carbon Monoxide Releasing Properties for the Management of Rheumatoid Arthritis
scientific article published on 23 July 2019
Synthesis and anti-inflammatory activity of sulfonamides and carboxylates incorporating trimellitimides: Dual cyclooxygenase/carbonic anhydrase inhibitory actions
scientific article published on 22 November 2018
Synthesis and antimalarial activity of novel chiral and achiral benzenesulfonamides bearing 1, 3, 4-oxadiazole moieties
scientific article
Synthesis and bioactivities of halogen bearing phenolic chalcones and their corresponding bis Mannich bases
scientific article published on 4 September 2016
Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity
scientific article published on 20 December 2018
Synthesis and bioactivity studies of 1-aryl-3-(2-hydroxyethylthio)-1-propanones.
scientific article published on 19 July 2016
Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides
scientific article published on 30 March 2016
Synthesis and biological activity of novel thiourea derivatives as carbonic anhydrase inhibitors
scientific article published on 25 March 2014
Synthesis and biological evaluation of a 99mTc-labelled sulfonamide conjugate for in vivo visualization of carbonic anhydrase IX expression in tumor hypoxia
scientific article published on 24 April 2010
Synthesis and biological evaluation of a new family of anti-benzylanilinosulfonamides as CA IX inhibitors
scientific article
Synthesis and biological evaluation of aminomethyl and alkoxymethyl derivatives as carbonic anhydrase, acetylcholinesterase and butyrylcholinesterase inhibitors
scientific article
Synthesis and biological evaluation of benzenesulphonamide-bearing 1,4,5-trisubstituted-1,2,3-triazoles possessing human carbonic anhydrase I, II, IV, and IX inhibitory activity.
scientific article published in December 2017
Synthesis and biological evaluation of coumarin-1,3,4-oxadiazole hybrids as selective carbonic anhydrase IX and XII inhibitors
scientific article published on 05 April 2019
Synthesis and biological evaluation of cyclic imides incorporating benzenesulfonamide moieties as carbonic anhydrase I, II, IV and IX inhibitors.
scientific article
Synthesis and biological evaluation of histamine Schiff bases as carbonic anhydrase I, II, IV, VII, and IX activators.
scientific article published in December 2017
Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamidesAQ3 as carbonic anhydrase isoforms I and II inhibitors
scientific article published on 01 December 2019
Synthesis and biological evaluation of novel 8-substituted quinoline-2-carboxamides as carbonic anhydrase inhibitors
scientific article published on 01 December 2019
Synthesis and biological evaluation of novel N,N'-diaryl cyanoguanidines acting as potent and selective carbonic anhydrase II inhibitors.
scientific article published on 16 January 2018
Synthesis and biological evaluation of novel aromatic and heterocyclic bis-sulfonamide Schiff bases as carbonic anhydrase I, II, VII and IX inhibitors.
scientific article published on 31 March 2017
Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy.
scientific article published on 23 February 2018
Synthesis and biological evaluation of some coumarin hybrids as selective carbonic anhydrase IX and XII inhibitors
scientific article published on 08 September 2020
Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors
scientific article published on 28 June 2019
Synthesis and biological profile of new 1,2,3,4-tetrahydroisoquinolines as selective carbonic anhydrase inhibitors
scientific article published on 12 October 2011
Synthesis and carbonic anhydrase I, II, IV and XII inhibitory properties of N-protected amino acid - sulfonamide conjugates
scientific article published on 21 February 2016
Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties
scientific article published on 21 February 2014
Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties
scientific article published on 21 July 2015
Synthesis and carbonic anhydrase I, II, VII, and IX inhibition studies with a series of benzo[d]thiazole-5- and 6-sulfonamides
scientific article published in December 2017
Synthesis and carbonic anhydrase activating properties of a series of 2-amino-imidazolines structurally related to clonidine1
scientific article published on 01 December 2020
Synthesis and carbonic anhydrase inhibition of a series of SLC-0111 analogs.
scientific article published on 18 March 2017
Synthesis and carbonic anhydrase inhibition of polycyclic imides incorporating N-benzenesulfonamide moieties
scientific article published on 29 July 2017
Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1,2,3-triazole chalcone hybrids
scientific article published on 08 April 2020
Synthesis and carbonic anhydrase inhibitory activities of new thienyl-substituted pyrazoline benzenesulfonamides
scientific article published on 19 July 2016
Synthesis and carbonic anhydrase inhibitory effects of new N-glycosylsulfonamides incorporating the phenol moiety.
scientific article published on 6 July 2016
Synthesis and carbonic anhydrase inhibitory properties of amino acid - coumarin/quinolinone conjugates incorporating glycine, alanine and phenylalanine moieties
scientific article published on 19 November 2015
Synthesis and carbonic anhydrase inhibitory properties of novel 4-(2-aminoethyl)benzenesulfonamide-dipeptide conjugates
scientific article published on 03 November 2018
Synthesis and carbonic anhydrase inhibitory properties of novel chalcone substituted benzenesulfonamides
scientific article published on 9 November 2016
Synthesis and carbonic anhydrase inhibitory properties of sulfamides structurally related to dopamine
scientific article published on 6 April 2013
Synthesis and carbonic anhydrase isoenzymes I, II, IX, and XII inhibitory effects of dimethoxybromophenol derivatives incorporating cyclopropane moieties
scientific article published on 24 December 2014
Synthesis and comparative carbonic anhydrase inhibition of new Schiff's bases incorporating benzenesulfonamide, methanesulfonamide, and methylsulfonylbenzene scaffolds
scientific article published on 28 August 2019
Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action
scientific article
Synthesis and cytotoxic activities of novel copper and silver complexes of 1,3-diaryltriazene-substituted sulfonamides
scientific article published on 01 December 2019
Synthesis and evaluation of 18F-labeled carbonic anhydrase IX inhibitors for imaging with positron emission tomography
scientific article published on 07 March 2013
Synthesis and evaluation of near-infrared fluorescent sulfonamide derivatives for imaging of hypoxia-induced carbonic anhydrase IX expression in tumors
scientific article
Synthesis and evaluation of pharmacological profile of 1-aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamides.
scientific article published on 7 April 2009
Synthesis and exploration of 2-morpholino-4-phenylthiazol-5-yl acrylamide derivatives for their effects against carbonic anhydrase I, II, IX and XII isoforms as a non-sulfonamide class of inhibitors
scientific article published on 05 September 2019
Synthesis and human carbonic anhydrase I, II, VA, and XII inhibition with novel amino acid-sulphonamide conjugates
scientific article published on 01 December 2020
Synthesis and human/bacterial carbonic anhydrase inhibition with a series of sulfonamides incorporating phthalimido moieties
scientific article published on 9 March 2017
Synthesis and in Vivo Biological Evaluation of (68)Ga-Labeled Carbonic Anhydrase IX Targeting Small Molecules for Positron Emission Tomography.
scientific article
Synthesis and inhibition potency of novel ureido benzenesulfonamides incorporating GABA as tumor-associated carbonic anhydrase IX and XII inhibitors
scientific article published on 04 September 2015
Synthesis and inhibitory potential towards acetylcholinesterase, butyrylcholinesterase and lipoxygenase of some variably substituted chalcones
scientific article published in February 2005
Synthesis and inhibitory properties of some carbamates on carbonic anhydrase and acetylcholine esterase
scientific article published on 17 March 2016
Synthesis and selective inhibitory effects of some 2-oxindole benzenesulfonamide conjugates on human carbonic anhydrase isoforms CA I, CA II, CA IX and CAXII
scientific article published on 23 December 2019
Synthesis and urease enzyme inhibitory effects of some dicoumarols
scientific article published in August 2004
Synthesis carbonic anhydrase enzyme inhibition and antioxidant activity of novel benzothiazole derivatives incorporating glycine, methionine, alanine, and phenylalanine moieties
scientific article published on 01 December 2019
Synthesis of 3,4-dihydroxypyrrolidine-2,5-dione and 3,5-dihydroxybenzoic acid derivatives and evaluation of the carbonic anhydrase I and II inhibition
scientific article published on 6 March 2015
Synthesis of 4,5-disubstituted-2-thioxo-1,2,3,4-tetrahydropyrimidines and investigation of their acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase I/II inhibitory and antioxidant activities
scientific article published on 22 June 2016
Synthesis of 4-(2-substituted hydrazinyl)benzenesulfonamides and their carbonic anhydrase inhibitory effects.
scientific article published on 5 June 2015
Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines.
scientific article published on 12 May 2016
Synthesis of 4-[2-(3,4-dimethoxybenzyl)cyclopentyl]-1,2-dimethoxybenzene Derivatives and Evaluations of Their Carbonic Anhydrase Isoenzymes Inhibitory Effects
scientific article
Synthesis of 4-sulfamoylphenyl-benzylamine derivatives with inhibitory activity against human carbonic anhydrase isoforms I, II, IX and XII.
scientific article published on 11 January 2016
Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action
scientific article published on 21 February 2015
Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII
scientific article published on 01 February 2014
Synthesis of Biologically Active Co(II), Cu(II), Ni(II) and Zn(II) Complexes of Symmetrically 1,1′‐Disubstituted Ferrocene‐Derived Compounds
Synthesis of C-cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases
scientific article published on 11 September 2012
Synthesis of N'-phenyl-N-hydroxyureas and investigation of their inhibitory activities on human carbonic anhydrases.
scientific article published in March 2018
Synthesis of N-alkyl (aril)-tetra pyrimidine thiones and investigation of their human carbonic anhydrase I and II inhibitory effects
scientific article published on 19 November 2015
Synthesis of Novel Selenides Bearing Benzenesulfonamide Moieties as Carbonic Anhydrase I, II, IV, VII, and IX Inhibitors
scientific article published on 7 November 2017
Synthesis of Schiff base derivatives of 4-(2-aminoethyl)-benzenesulfonamide with inhibitory activity against carbonic anhydrase isoforms I, II, IX and XII.
scientific article published on 10 April 2015
Synthesis of a new series of 3-functionalised-1-phenyl-1,2,3-triazole sulfamoylbenzamides as carbonic anhydrase I, II, IV and IX inhibitors
scientific article published on 01 December 2019
Synthesis of a new series of N⁴-substituted 4-(2-aminoethyl)benzenesulfonamides and their inhibitory effect on human carbonic anhydrase cytosolic isozymes I and II and transmembrane tumor-associated isozymes IX and XII
scientific article published on 05 July 2014
Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action
scientific article published on 31 March 2015
Synthesis of a novel affinity gel for the purification of carbonic anhydrases
scientific article published on 18 June 2014
Synthesis of aminocyanopyrazoles via a multi-component reaction and anti-carbonic anhydrase inhibitory activity of their sulfamide derivatives against cytosolic and transmembrane isoforms.
scientific article published on 27 September 2012
Synthesis of an acridine orange sulfonamide derivative with potent carbonic anhydrase IX inhibitory action
scientific article published in December 2017
Synthesis of benzensulfonamides linked to quinazoline scaffolds as novel carbonic anhydrase inhibitors
scientific article published on 06 March 2019
Synthesis of bulky-tailed sulfonamides incorporating pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-1(5H)-yl) moieties and evaluation of their carbonic anhydrases I, II, IV and IX inhibitory effects.
scientific article
Synthesis of calix[4]azacrown substituted sulphonamides with antioxidant, acetylcholinesterase, butyrylcholinesterase, tyrosinase and carbonic anhydrase inhibitory action
scientific article published on 01 December 2020
Synthesis of coumarin derivatives with cytotoxic, antibacterial and antifungal activity
scientific article published in August 2004
Synthesis of coumarin-sulfonamide derivatives and determination of their cytotoxicity, carbonic anhydrase inhibitory and molecular docking studies
scientific article published on 14 September 2019
Synthesis of diaryl ethers with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions
scientific article published on 31 May 2016
Synthesis of different thio-scaffolds bearing sulfonamide with subnanomolar carbonic anhydrase II and IX inhibitory properties and X-ray investigations for their inhibitory mechanism
scientific article published on 20 September 2018
Synthesis of glycoconjugate carbonic anhydrase inhibitors by ruthenium-catalysed azide-alkyne 1,3-dipolar cycloaddition
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Synthesis of isoxazole-containing sulfonamides with potent carbonic anhydrase II and VII inhibitory properties
scientific article published on 11 January 2017
Synthesis of new 3-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-benzenesulfonamides with strong inhibition properties against the tumor associated carbonic anhydrases IX and XII.
scientific article
Synthesis of nitrogen, phosphorus, selenium and sulfur-containing heterocyclic compounds - Determination of their carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glycosidase inhibition properties
scientific article published on 26 August 2020
Synthesis of novel 4-functionalized 1,5-diaryl-1,2,3-triazoles containing benzenesulfonamide moiety as carbonic anhydrase I, II, IV and IX inhibitors
scientific article published on 14 March 2018
Synthesis of novel 5-amino-1,3,4-thiadiazole-2-sulfonamide containing acridine sulfonamide/carboxamide compounds and investigation of their inhibition effects on human carbonic anhydrase I, II, IV and VII.
scientific article published on 2 January 2018
Synthesis of novel acridine and bis acridine sulfonamides with effective inhibitory activity against the cytosolic carbonic anhydrase isoforms II and VII.
scientific article published on 17 July 2013
Synthesis of novel acridine bis-sulfonamides with effective inhibitory activity against the carbonic anhydrase isoforms I, II, IX and XII.
scientific article published on 15 September 2015
Synthesis of novel acyl selenoureido benzensulfonamides as carbonic anhydrase I, II, VII and IX inhibitors.
scientific article published on 9 May 2017
Synthesis of novel benzenesulfamide derivatives with inhibitory activity against human cytosolic carbonic anhydrase I and II and Vibrio cholerae α- and β-class enzymes.
scientific article published in December 2018
Synthesis of novel benzenesulfonamide bearing 1,2,3-triazole linked hydroxy-trifluoromethylpyrazolines and hydrazones as selective carbonic anhydrase isoforms IX and XII inhibitors
scientific article published on 03 January 2019
Synthesis of novel biologically active methylene derivatives of sydnones
Synthesis of novel dipeptide sulfonamide conjugates with effective carbonic anhydrase I, II, IX, and XII inhibitory properties
scientific article published on 27 August 2018
Synthesis of novel isoindoline-1,3-dione-based oximes and benzenesulfonamide hydrazones as selective inhibitors of the tumor-associated carbonic anhydrase IX
scientific article published on 24 July 2018
Synthesis of novel tellurides bearing benzensulfonamide moiety as carbonic anhydrase inhibitors with antitumor activity
scientific article published on 05 August 2019
Synthesis of pro-apoptotic indapamide derivatives as anticancer agents
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Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against human α- and bacterial/fungal β-carbonic anhydrases
scientific article published on 21 July 2011
Synthesis of some N-aroyl-2-oxindole benzenesulfonamide conjugates with carbonic anhydrase inhibitory activity
scientific article published on 29 January 2020
Synthesis of some tetrahydropyrimidine-5-carboxylates, determination of their metal chelating effects and inhibition profiles against acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase
scientific article published on 28 March 2016
Synthesis of sulfonamide conjugates of Cu(II), Ga(III), In(III), Re(V) and Zn(II) complexes: carbonic anhydrase inhibition studies and cellular imaging investigations.
scientific article published in March 2015
Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity
scientific article published on 26 July 2015
Synthesis of sulfonamides with effective inhibitory action against Porphyromonas gingivalis γ-carbonic anhydrase
scientific article published on 18 June 2014
Synthesis of two phloroglucinol derivatives with cinnamyl moieties as inhibitors of the carbonic anhydrase isozymes I and II: an in vitro study
scientific article published on 13 May 2016
Synthesis, X-ray structure, in silico calculation, and carbonic anhydrase inhibitory properties of benzylimidazole metal complexes
scientific article published on 01 December 2018
Synthesis, biological activity and multiscale molecular modeling studies for coumaryl-carboxamide derivatives as selective carbonic anhydrase IX inhibitors.
scientific article published in December 2017
Synthesis, biological activity and multiscale molecular modeling studies of bis-coumarins as selective carbonic anhydrase IX and XII inhibitors with effective cytotoxicity against hepatocellular carcinoma
scientific article published on 07 March 2019
Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors
scientific article published on 02 November 2019
Synthesis, biological evaluation and computational studies of novel iminothiazolidinone benzenesulfonamides as potent carbonic anhydrase II and IX inhibitors.
scientific article published on 31 January 2018
Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors
scientific article published on 28 August 2019
Synthesis, biological evaluation and in silico studies with 4-benzylidene-2-phenyl-5(4H)-imidazolone-based benzenesulfonamides as novel selective carbonic anhydrase IX inhibitors endowed with anticancer activity
scientific article published on 02 July 2019
Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines
scientific article published on 24 October 2016
Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives
scientific article published on 15 April 2015
Synthesis, characterisation, biological evaluation and in silico studies of sulphonamide Schiff bases
scientific article published on 01 December 2020
Synthesis, characterization and biological studies of sulfonamide Schiff's bases and some of their metal derivatives
scientific article published on 3 May 2011
Synthesis, characterization and carbonic anhydrase inhibitory activity of novel benzothiazole derivatives
scientific article published on 24 November 2015
Synthesis, computational studies and assessment of in vitro inhibitory activity of squalene derivatives as carbonic anhydrase inhibitors
scientific article published on 03 August 2020
Synthesis, computational studies and assessment of in vitro inhibitory activity of umbelliferon-based compounds against tumour-associated carbonic anhydrase isoforms IX and XII
scientific article published on 01 December 2020
Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones
scientific article published on 01 December 2019
Synthesis, cytotoxicity and carbonic anhydrase inhibitory activities of new pyrazolines
scientific article published on 31 August 2016
Synthesis, structure and bioactivity of primary sulfamate-containing natural products
scientific article published on 16 April 2018
Synthesis, structure-activity relationship studies, and X-ray crystallographic analysis of arylsulfonamides as potent carbonic anhydrase inhibitors
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Synthetic Strategies and Computational Inhibition Activity Study for Triazinyl-Substituted Benzenesulfonamide Conjugates with Polar and Hydrophobic Amino Acids as Inhibitors of Carbonic Anhydrases
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scientific article published on 22 May 2020
Tail approach synthesis of novel benzenesulfonamides incorporating 1,3,4-oxadiazole hybrids as potent inhibitor of carbonic anhydrase I, II, IX, and XII isoenzymes
scientific article published on 10 March 2020
Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies
scientific article published on April 2009
Target-based drug discovery through inversion of quantitative structure-drug-property relationships and molecular simulation: CA IX-sulphonamide complexes
scientific article published on 01 December 2018
Targeting Bacterial Metalloenzymes: A New Strategy for the Development of Anti-Infective Agents
article
Targeting Carbonic Anhydrases with Fluorescent BODIPY-Labelled Sulfonamides
Targeting Malassezia species for novel synthetic and natural antidandruff agents.
scientific article published on 4 April 2017
Targeting Tumor Associated Carbonic Anhydrases IX and XII: Highly Isozyme Selective Coumarin and Psoralen Inhibitors
scientific article published on 06 June 2018
Targeting carbonic anhydrase IX by nitroimidazole based sulfamides enhances the therapeutic effect of tumor irradiation: a new concept of dual targeting drugs.
scientific article published on 9 July 2013
Targeting cysteine residues of biomolecules: new approaches for the design of antiviral and anticancer drugs
scientific article
Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors
scientific article
Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors.
scientific article published on 17 March 2011
Targeting tumor-associated carbonic anhydrase IX in cancer therapy
scientific article published on 25 September 2006
Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium
scientific article
Tellurides Bearing Sulfonamides as Novel Inhibitors of Leishmanial Carbonic Anhydrase with Potent Antileishmanial Activity
scientific article published on 09 April 2020
The Carbonic Anhydrase IX inhibitor SLC-0111 as emerging agent against the mesenchymal stem cell-derived pro-survival effects on melanoma cells
scientific article published on 01 December 2020
The Crystal Structure of a hCA VII Variant Provides Insights into the Molecular Determinants Responsible for Its Catalytic Behavior
scientific article published on 24 May 2018
The Effect of Substituted Benzene-Sulfonamides and Clinically Licensed Drugs on the Catalytic Activity of CynT2, a Carbonic Anhydrase Crucial for Escherichia coli Life Cycle
scientific article published on 11 June 2020
The Glitazone Class of Drugs as Carbonic Anhydrase Inhibitors—A Spin-Off Discovery from Fragment Screening
scientific article published in 2021
The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management
scientific article published on 22 February 2019
The Warburg Effect and the Hallmarks of Cancer.
scientific article published on 31 October 2016
The alpha and beta classes carbonic anhydrases from Helicobacter pylori as novel drug targets
scientific article published on January 2008
The alpha-carbonic anhydrase from the malaria parasite and its inhibition
scientific article
The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides
scientific article published on 23 July 2012
The antibiotic furagin and its derivatives are isoform-selective human carbonic anhydrase inhibitors
scientific article published on 01 December 2020
The anticonvulsant sulfamide JNJ-26990990 and its S,S-dioxide analog strongly inhibit carbonic anhydrases: solution and X-ray crystallographic studies
scientific article
The antifungal activity of sulfonylamido derivatives of 2-aminophenoxathiin and related compounds
The carbonic anhydrase IX inhibitor SLC-0111 sensitises cancer cells to conventional chemotherapy
scholarly article by Elena Andreucci et al published December 2019 in Journal of Enzyme Inhibition and Medicinal Chemistry
The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors
scientific article
The crystal structures of 2-(4-benzhydrylpiperazin-1-yl)- N -(4-sulfamoylphenyl)acetamide in complex with human carbonic anhydrase II and VII provide insights into selective CA inhibitor development
The development of topically acting carbonic anhydrase inhibitors as anti-glaucoma agents
scientific article published on January 2007
The development of topically acting carbonic anhydrase inhibitors as antiglaucoma agents
scientific article
The effect of caffeic acid phenethyl ester (CAPE) on metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, lactoperoxidase, and carbonic anhydrase isoenzymes I, II, IX, and XII
scientific article published on 09 October 2015
The effects of some avermectins on bovine carbonic anhydrase enzyme
scientific article published on 24 July 2015
The effects of some bromophenols on human carbonic anhydrase isoenzymes
scientific article published on 02 July 2015
The extremo-α-carbonic anhydrase (CA) from Sulfurihydrogenibium azorense, the fastest CA known, is highly activated by amino acids and amines
scientific article published on 20 December 2012
The extremo-α-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium azorense is highly inhibited by sulfonamides
scientific article published on 31 May 2013
The first activation studies of the η-carbonic anhydrase from the malaria parasite Plasmodium falciparum with amines and amino acids
scholarly article by Andrea Angeli et al published October 2018 in Bioorganic Chemistry
The first activation study of a bacterial carbonic anhydrase (CA). The thermostable α-CA from Sulfurihydrogenibium yellowstonense YO3AOP1 is highly activated by amino acids and amines.
scientific article published on 30 August 2012
The first activation study of a δ-carbonic anhydrase: TweCAδ from the diatom Thalassiosira weissflogii is effectively activated by amines and amino acids
scientific article published in December 2018
The first activation study of the β-carbonic anhydrases from the pathogenic bacteria Brucella suis and Francisella tularensis with amines and amino acids
scientific article published on 01 December 2019
The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: the carbonic anhydrase I-topiramate complex
scientific article
The functional and physical relationship between the DRA bicarbonate transporter and carbonic anhydrase II
scientific article (publication date: November 2002)
The gram-negative bacterium <i>Escherichia coli</i> as a model for testing the effect of carbonic anhydrase inhibition on bacterial growth
scientific article published in 2022
The history and rationale of using carbonic anhydrase inhibitors in the treatment of peptic ulcers. In memoriam Ioan Puşcaş (1932-2015).
scientific article published on 25 June 2015
The human carbonic anhydrase isoenzymes I and II (hCA I and II) inhibition effects of trimethoxyindane derivatives
scientific article published on 20 February 2015
The human carbonic anhydrase isoenzymes I and II inhibitory effects of some hydroperoxides, alcohols, and acetates
scientific article published on 18 December 2015
The impact of hydroquinone on acetylcholine esterase and certain human carbonic anhydrase isoenzymes (hCA I, II, IX, and XII)
scientific article published on 14 January 2015
The inhibitory effects of phenolic Mannich bases on carbonic anhydrase I and II isoenzymes.
scientific article published on 10 January 2016
The management of diabetes mellitus-imperative role of natural products against dipeptidyl peptidase-4, α-glucosidase and sodium-dependent glucose co-transporter 2 (SGLT2)
scientific article published on 04 February 2019
The management of glaucoma and macular degeneration
scientific article published on 01 October 2019
The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.
scientific article
The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors
scientific article published on 31 August 2009
The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths
scientific article
The role of carbonic anhydrase IX in hypoxia control in OSCC.
scientific article published on 14 March 2012
The role of carbonic anhydrases in extinction of contextual fear memory
scientific article published on 22 June 2020
The structural comparison between membrane-associated human carbonic anhydrases provides insights into drug design of selective inhibitors
scientific article
The sulfamide motif in the design of enzyme inhibitors
scientific article published in January 2006
The synthesis of (Z)-4-oxo-4-(arylamino)but-2-enoic acids derivatives and determination of their inhibition properties against human carbonic anhydrase I and II isoenzymes
scientific article published on 24 August 2015
The synthesis of novel sulfamides derived from β-benzylphenethylamines as acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase enzymes inhibitors
scientific article published on 23 August 2017
The synthesis of some β-lactams and investigation of their metal-chelating activity, carbonic anhydrase and acetylcholinesterase inhibition profiles
scientific article published on 13 April 2016
The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII
publication published on 01 December 2022
The x-ray structure of the adduct between NAMI-A and carbonic anhydrase provides insights into the reactivity of this metallodrug with proteins
scientific article
The zinc - but not cadmium - containing ζ-carbonic from the diatom Thalassiosira weissflogii is potently activated by amines and amino acids
scientific article published on 26 May 2018
The zinc coordination pattern in the η-carbonic anhydrase from Plasmodium falciparum is different from all other carbonic anhydrase genetic families
scientific article published on 28 February 2015
The β-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides
scientific article
The β-carbonic anhydrases from Mycobacterium tuberculosis as drug targets.
scientific article published on January 2010
The γ-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae is potently activated by amines and amino acids
scientific article
The η-class carbonic anhydrases as drug targets for antimalarial agents
scientific article published on 12 December 2014
Therapeutic applications of glycosidic carbonic anhydrase inhibitors.
scientific article published on May 2009
Therapeutic applications of serine protease inhibitors
Therapeutic applications of sulfamates
scholarly article by Jean-Yves Winum et al published September 2004 in Expert Opinion on Therapeutic Patents
Therapeutic compounds: patent evaluation of WO2011011652A1
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scientific article published on 09 May 2011
Therapeutic potential of sulfamides as enzyme inhibitors.
scientific article
Thermostability enhancement of the α-carbonic anhydrase from Sulfurihydrogenibium yellowstonense by using the anchoring-and-self-labelling-protein-tag system (ASL)
scientific article published on 01 December 2019
Thiol-ene click chemistry for the synthesis of highly effective glycosyl sulfonamide carbonic anhydrase inhibitors.
scientific article published on 20 May 2013
Thioxocoumarins Show an Alternative Carbonic Anhydrase Inhibition Mechanism Compared to Coumarins
Three new aromatic sulfonamide inhibitors of carbonic anhydrases I, II, IV and XII
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scientific article published on February 3, 2012
Time course of red blood cell intracellular pH recovery following short-circuiting in relation to venous transit times in rainbow trout, Oncorhynchus mykiss
scientific article published on 11 April 2018
Time resolved SAXS to study the complexation of siRNA with cationic micelles of divalent surfactants
scientific article published on 01 April 2014
Topological modeling of lipophilicity, diuretic activity, and carbonic inhibition activity of benzene sulfonamides: a molecular connectivity approach
scientific article
Toxicity evaluation of sulfamides and coumarins that efficiently inhibit human carbonic anhydrases
scientific article published on 01 December 2020
Transition metal acetylsalicylates and their anti-inflammatory activity
scientific article (publication date: April 2002)
Transport characteristics of L-carnosine and the anticancer derivative 4-toluenesulfonylureido-carnosine in a human epithelial cell line
scientific article published on September 2002
Treatment of glaucoma and ocular hypertension using rho kinase inhibitors: patent evaluation of US2018244666 and US2018256595
scientific article published on 22 August 2019
Treatment of sleep apnea with a combination of a carbonic anhydrase inhibitor and an aldosterone antagonist: a patent evaluation of CA2958110 and IN6616DEN2012
scientific article published on 16 July 2018
Tricyclic Sulfonamides Incorporating Benzothiopyrano[4,3-c]pyrazole and Pyridothiopyrano[4,3-c]pyrazole Effectively Inhibit α- and β-Carbonic Anhydrase: X-ray Crystallography and Solution Investigations on 15 Isoforms
article
Trimeric Radiofluorinated Sulfonamide Derivatives to Achieve In Vivo Selectivity for Carbonic Anhydrase IX-Targeted PET Imaging.
scientific article published on 23 July 2015
Tumor microenvironmental changes induced by the sulfamate carbonic anhydrase IX inhibitor S4 in a laryngeal tumor model
scientific article
Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths
scientific article
Tumor-associated carbonic anhydrase isoform IX and XII inhibitory properties of certain isatin-bearing sulfonamides endowed with in vitro antitumor activity towards colon cancer
scientific article published on 07 September 2018
Tuning the Dual Inhibition of Carbonic Anhydrase and Cyclooxygenase by Dihydrothiazole Benzensulfonamides
scientific article published on 17 September 2018
Tyrosinase inhibition: conformational analysis based studies on molecular dynamics calculations of bipiperidine based inhibitors
scientific article published on August 2005
Unconventional amino acids in medicinal chemistry: First report on taurine merged within carbonic anhydrase inhibitors
scientific article published on 26 August 2020
Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition
scientific article
Unprotected primary sulfonamide group facilitates ring-forming cascade en route to polycyclic [1,4]oxazepine-based carbonic anhydrase inhibitors.
scientific article published on 21 November 2017
Unsymmetrical 1,1'-disubstituted ferrocenes: synthesis of Co(ii), Cu(ii), Ni(ii) and Zn(ii) chelates of ferrocenyl -1-thiadiazolo-1'-tetrazole, -1-thiadiazolo-1'-triazole and -1-tetrazolo-1'-triazole with antimicrobial properties
scientific article published in August 2002
Update on the development of HIV entry inhibitors
article
Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis.
scientific article
Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines.
scientific article
Use of an immobilised thermostable α-CA (SspCA) for enhancing the metabolic efficiency of the freshwater green microalga Chlorella sorokiniana
scientific article published on 01 December 2020
Vanillin enones as selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII. The out of the active site pocket for the design of selective inhibitors?
scientific article published on 01 December 2021
Vasorelaxation induced by dodoneine is mediated by calcium channels blockade and carbonic anhydrase inhibition on vascular smooth muscle cells.
scientific article
Virtual screening-driven identification of human carbonic anhydrase inhibitors incorporating an original, new pharmacophore
scientific article published in 2011
Which carbonic anhydrases are targeted by the antiepileptic sulfonamides and sulfamates?
scientific article published in September 2009
Why hasn't there been more progress in new Chagas disease drug discovery?
scientific article published on 31 October 2019
X-Ray Crystallography of Carbonic Anhydrase Inhibitors and Its Importance in Drug Design
X-ray crystallography of Epacadostat in adduct with Carbonic Anhydrase IX
scientific article published on 14 February 2020
X-ray crystallography-promoted drug design of carbonic anhydrase inhibitors
scientific article
X-ray structure of the first `extremo-α-carbonic anhydrase', a dimeric enzyme from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1
scientific article
Xanthates and trithiocarbonates strongly inhibit carbonic anhydrases and show antiglaucoma effects in vivo.
scientific article published on 16 May 2013
Zeta-carbonic anhydrases show CS<sub>2</sub> hydrolase activity: A new metabolic carbon acquisition pathway in diatoms?
scientific article published on 05 June 2021
Zinc Binding Functions in the Design of Carbonic Anhydrase Inhibitors
scholarly article
Zinc complexes of benzothiazole-derived Schiff bases with antibacterial activity
scientific article published in June 2003
[(18)F]VM4-037 MicroPET Imaging and Biodistribution of Two In Vivo CAIX-Expressing Tumor Models.
scientific article published on 24 February 2015
[(Cp-R)M(CO)3] (M=Re or 99mTc) Arylsulfonamide, arylsulfamide, and arylsulfamate conjugates for selective targeting of human carbonic anhydrase IX
scientific article
o-Benzenedisulfonimido-sulfonamides are potent inhibitors of the tumor-associated carbonic anhydrase isoforms CA IX and CA XII
scientific article published on 04 January 2013
pH regulators to target the tumor immune microenvironment in human hepatocellular carcinoma.
scientific article
pH-Sensitive Multiligand Gold Nanoplatform Targeting Carbonic Anhydrase IX Enhances the Delivery of Doxorubicin to Hypoxic Tumor Spheroids and Overcomes the Hypoxia-Induced Chemoresistance
scientific article published on 15 May 2018
α,γ-Diketocarboxylic Acids and Their Esters Act as Carbonic Anhydrase IX and XII Selective Inhibitors
scientific article published on 19 February 2019
α-Carbonic Anhydrases Possess Thioesterase Activity
scientific article published on 19 January 2015
α-Carbonic anhydrases are strongly activated by spinaceamine derivatives
scientific article published on 21 January 2019
α-Carbonic anhydrases are sulfatases with cyclic diol monosulfate esters
article
β-CA-specific inhibitor dithiocarbamate Fc14-584B: a novel antimycobacterial agent with potential to treat drug-resistant tuberculosis.
scientific article published on December 2017