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List of works by Jan Rehwinkel

A Balancing Act: MDA5 in Antiviral Immunity and Autoinflammation

scholarly article by Antonio Gregorio Dias Junior et al published 1 January 2019 in Trends in Microbiology

A G1-like state allows HIV-1 to bypass SAMHD1 restriction in macrophages

scientific article published on 25 January 2017

A conserved role for cytoplasmic poly(A)-binding protein 1 (PABPC1) in nonsense-mediated mRNA decay

scientific article published on 22 February 2007

A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing

scientific article

A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis

scientific article published on 27 March 2019

A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1.

scientific article published on 9 March 2017

Activation of MDA5 requires higher-order RNA structures generated during virus infection

scientific article

Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity

scientific article

Antiviral activity of bone morphogenetic proteins and activins

scientific article published on 3 December 2018

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5'-diphosphates

scientific article

Author Correction: SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

scientific article published on 21 October 2020

B Cells Producing Type I Interferon Modulate Macrophage Polarization in Tuberculosis

scientific article published on 21 November 2017

Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration

scientific article published on 12 July 2021

Deadenylation is a widespread effect of miRNA regulation

scientific article

Deoxyguanosine is a TLR7 agonist

scientific article published on 14 November 2019

Enhanced immunogenicity of mitochondrial-localized proteins in cancer cells

scientific article published on 23 March 2020

Erratum to: Purification of Cyclic GMP-AMP from Viruses and Measurement of Its Activity in Cell Culture

scientific article published in January 2017

Exposing viruses: RNA patterns sensed by RIG-I-like receptors

scientific article published on 31 March 2010

Fractional response analysis reveals logarithmic cytokine responses in cellular populations

Full Genome Sequence and sfRNA Interferon Antagonist Activity of Zika Virus from Recife, Brazil

scientific article (publication date: October 2016)

Genome-wide analysis of mRNAs regulated by Drosha and Argonaute proteins in Drosophila melanogaster

scientific article published on April 2006

Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster

scientific article published on 9 May 2004

Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila

scientific article

Hypoxia Regulates Endogenous Double-Stranded RNA Production via Reduced Mitochondrial DNA Transcription

scientific article published on 24 November 2021

Hypoxia induces transcriptional and translational downregulation of the type I interferon (IFN) pathway in multiple cancer cell types

scientific article published on 28 October 2020

Identification of SARS-CoV2-mediated suppression of NRF2 signaling reveals a potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

scientific article

Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells

scientific article published on 18 February 2014

Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signalling

scientific article published on 23 March 2018

Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence.

scientific article published on 31 July 2017

Is anti-viral defence the evolutionary origin of mRNA turnover? (Comment on DOI 10.1002/bies.201600100).

scientific article published on August 2016

Keeping your armour intact: how HIV-1 evades detection by the innate immune system: HIV-1 capsid controls detection of reverse transcription products by the cytosolic DNA sensor cGAS.

scientific article published on 29 April 2014

MicroRNAs silence gene expression by repressing protein expression and/or by promoting mRNA decay.

scientific article published on January 2006

Mitochondrial double-stranded RNA triggers antiviral signalling in humans

scientific article published in Nature

Mouse knockout models for HIV-1 restriction factors

scientific article

Mouse superkiller-2-like helicase DDX60 is dispensable for type I IFN induction and immunity to multiple viruses.

scientific article published on 10 September 2015

Multi-Modal Characterization of Monocytes in Idiopathic Pulmonary Fibrosis Reveals a Primed Type I Interferon Immune Phenotype

scientific article published on 05 March 2021

Mutations in COPA lead to abnormal trafficking of STING to the Golgi and interferon signaling

scientific article published on 01 November 2020

Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling

article published in the Proceedings of the National Academy of Sciences of the United States of America

Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets

scientific article

Nonsense-mediated mRNA decay: target genes and functional diversification of effectors

article

Nucleic Acid Sensors and Programmed Cell Death

scientific article published on 29 November 2019

PA-X antagonises MAVS-dependent accumulation of early type I interferon messenger RNAs during influenza A virus infection

scientific article published on 10 May 2019

PNP inhibitors selectively kill cancer cells lacking SAMHD1

scientific article published on 20 September 2020

PYHIN proteins: center stage in DNA sensing

Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity

scientific article

Purification of Cyclic GMP-AMP from Viruses and Measurement of Its Activity in Cell Culture

scientific article

RECONsidering Sensing of Cyclic Dinucleotides

scientific article published in March 2017

RIG-I Plays a Dominant Role in the Induction of Transcriptional Changes in Zika Virus-Infected Cells, which Protect from Virus-Induced Cell Death

scientific article published on 16 June 2020

RIG-I detects viral genomic RNA during negative-strand RNA virus infection

scientific article

RIG-I-like receptors: their regulation and roles in RNA sensing

scientific article published on 13 March 2020

RIGorous detection: exposing virus through RNA sensing.

scientific article published in January 2010

RNA degradation in antiviral immunity and autoimmunity

scientific article

RNA sensing: the more RIG‐I the merrier? ⬇️

scientific article published on August 6, 2013

Redox homeostasis maintained by GPX4 facilitates STING activation

scientific article published on 15 June 2020

Regulation and inhibition of the DNA sensor cGAS

scientific article published on 05 November 2020

Restriction by SAMHD1 Limits cGAS/STING-Dependent Innate and Adaptive Immune Responses to HIV-1.

scientific article published on 27 July 2016

SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP

scientific article published on 01 May 2020

SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage.

scientific article

SAMHD1-dependent retroviral control and escape in mice.

scientific article published on 19 July 2013

SAMHD1-dependent retroviral control and escape in mice.

scientific article

SAMHD1-mediated dNTP degradation is required for efficient DNA repair during antibody class switch recombination

scientific article published on 08 June 2020

SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

scientific article published on 02 October 2020

Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation

scientific article published on 01 July 2020

Sensing of viral and endogenous RNA by ZBP1/DAI induces necroptosis

scientific article

Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing

scientific article

Targeting the viral Achilles’ heel: recognition of 5′-triphosphate RNA in innate anti-viral defence ⬇️

scientific article published on May 23, 2013

The RNA sensor MDA5 detects SARS-CoV-2 infection

scientific article

The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses

scientific article published on 27 April 2022

The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha

scientific article

Viruses transfer the antiviral second messenger cGAMP between cells

scientific article

cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing

scientific article published on 23 November 2020

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

scientific article

mRNA quality control: an ancient machinery recognizes and degrades mRNAs with nonsense codons.

scientific article published on 21 May 2007

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