Search filters

List of works by Daniel Hartl

A New Take on John Maynard Smith's Concept of Protein Space for Understanding Molecular Evolution

scientific article

A genome-wide map of diversity in Plasmodium falciparum

scientific article published on 10 December 2006

A pivot mutation impedes reverse evolution across an adaptive landscape for drug resistance in Plasmodium vivax

scientific article published on 25 January 2016

Accelerated rates of intron gain/loss and protein evolution in duplicate genes in human and mouse malaria parasites

scientific article

Accessible mutational trajectories for the evolution of pyrimethamine resistance in the malaria parasite Plasmodium vivax

scientific article

Adaptive Landscape by Environment Interactions Dictate Evolutionary Dynamics in Models of Drug Resistance

scientific article

Adaptive impact of the chimeric gene Quetzalcoatl in Drosophila melanogaster

scientific article

Anomalies in the expression profile of interspecific hybrids of Drosophila melanogaster and Drosophila simulans

scientific article

Application of genomics to field investigations of malaria by the international centers of excellence for malaria research

scientific article

Bayesian analysis of gene expression levels: statistical quantification of relative mRNA level across multiple strains or treatments

scientific article

Biophysical principles predict fitness landscapes of drug resistance.

scientific article published on 29 February 2016

COIL: a methodology for evaluating malarial complexity of infection using likelihood from single nucleotide polymorphism data

scientific article

Chimeric genes as a source of rapid evolution in Drosophila melanogaster

scientific article

Climate change and the integrity of science

scientific article

Clonal outbreak of Plasmodium falciparum infection in eastern Panama

scientific article

Cohort Profile: The Madagascar Health and Environmental Research (MAHERY) study in north-eastern Madagascar

scientific article published on 14 June 2017

Compensatory mutations restore fitness during the evolution of dihydrofolate reductase

scientific article

Convergent loss of an anciently duplicated, functionally divergent RH2 opsin gene in the fugu and Tetraodon pufferfish lineages

scientific article

DNA sequence artifacts and the estimation of time to the most recent common ancestor (TMRCA) of Plasmodium falciparum

scientific article published on 01 August 2003

De Novo Mutations Resolve Disease Transmission Pathways in Clonal Malaria.

scientific article

Different regulatory mechanisms underlie similar transposable element profiles in pufferfish and fruitflies

scientific article published in September 2004

Dramatic Changes in Malaria Population Genetic Complexity in Dielmo and Ndiop, Senegal, Revealed Using Genomic Surveillance

scientific article published on 9 January 2018

Duplication, gene conversion, and genetic diversity in the species-specific acyl-CoA synthetase gene family of Plasmodium falciparum

scientific article (publication date: November 2006)

Effects of X-linkage and sex-biased gene expression on the rate of adaptive protein evolution in Drosophila

scientific article published on 13 May 2008

Epigenetic memory at malaria virulence genes

scholarly article

Evidence for maternally transmitted small interfering RNA in the repression of transposition in Drosophila virilis

scientific article

Evolution of noncoding and silent coding sites in the Plasmodium falciparum and Plasmodium reichenowi genomes

scientific article published on 27 April 2005

Excess Polymorphisms in Genes for Membrane Proteins in Plasmodium falciparum

scientific article published in Science

Experimental evolution for niche breadth in bacteriophage T4 highlights the importance of structural genes

scientific article published on 28 November 2019

Extensive microsatellite diversity in the human malaria parasite Plasmodium vivax

scientific article published on 15 January 2008

Fitness Trade-Offs in the Evolution of Dihydrofolate Reductase and Drug Resistance in Plasmodium falciparum ⬇️

scientific article published on May 23, 2011

Formation and longevity of chimeric and duplicate genes in Drosophila melanogaster

scientific article

Gene conversion as a source of nucleotide diversity in Plasmodium falciparum

scientific article published on 2 April 2003

Genetic background and PfKelch13 affect artemisinin susceptibility of PfCoronin mutants in Plasmodium falciparum

scientific article published on 28 December 2020

Genetic diversity and selection at the Plasmodium vivax apical membrane antigen-1 (PvAMA-1) locus in a Sri Lankan population

scientific article published on 22 January 2007

Genetic diversity in yeast assessed with whole-genome oligonucleotide arrays

scientific article published on January 2003

Genetic evidence that the Makira region in northeastern Madagascar is a hotspot of malaria transmission

scientific article published on 20 December 2016

Genetic relatedness analysis reveals the cotransmission of genetically related Plasmodium falciparum parasites in Thiès, Senegal

scientific article published on 24 January 2017

Genetic surveillance detects both clonal and epidemic transmission of malaria following enhanced intervention in Senegal

scientific article

Genome evolution and developmental constraint in Caenorhabditis elegans

scientific article published in May 2002

Genome-Wide Association Studies of Drug-Resistance Determinants

scientific article published on 27 October 2016

Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence

scientific article published on 15 December 2008

Genomic heterogeneity in the density of noncoding single-nucleotide and microsatellite polymorphisms in Plasmodium falciparum

scientific article published on 14 August 2006

Genomic sequencing of Plasmodium falciparum malaria parasites from Senegal reveals the demographic history of the population

scientific article

Geographic structure of Plasmodium vivax: microsatellite analysis of parasite populations from Sri Lanka, Myanmar, and Ethiopia

scientific article published in February 2010

Glycophorin B is the erythrocyte receptor of Plasmodium falciparum erythrocyte-binding ligand, EBL-1

scholarly article

Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance

scientific article

Horizontal acquisition of divergent chromosomal DNA in bacteria: effects of mutator phenotypes

scientific article

Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum

scientific article

Low-complexity regions in Plasmodium falciparum: missing links in the evolution of an extreme genome

scientific article

Malaria life cycle intensifies both natural selection and random genetic drift

scientific article

Malaria: a peek at the var variorum

scientific article published on 30 October 2007

Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria

scientific article

Missense meanderings in sequence space: a biophysical view of protein evolution

scientific article

Modeling malaria genomics reveals transmission decline and rebound in Senegal

scientific article published on 4 May 2015

Modeling the genetic relatedness of Plasmodium falciparum parasites following meiotic recombination and cotransmission

scientific article published on 9 January 2018

Mosquito Vectors and the Globalization of Plasmodium falciparum Malaria

scientific article

Mutational reversions during adaptive protein evolution

scientific article published on 07 June 2007

Mutations in actin-binding protein coronin confer reduced artemisinin susceptibility

article published in the Proceedings of the National Academy of Sciences of the United States of America

On the abundance, amino acid composition, and evolutionary dynamics of low-complexity regions in proteins

scientific article published on 11 May 2006

Optimization of gene expression by natural selection

scholarly article

Overdispersion of the molecular clock varies between yeast, Drosophila and mammals

scientific article published on 27 May 2008

Overdispersion of the molecular clock: temporal variation of gene-specific substitution rates in Drosophila

scientific article published on 13 May 2008

Parasitology. A game of cat and mouth

scientific article published on 01 January 2003

Patterns of insertion and deletion in contrasting chromatin domains

scientific article published in December 2002

Patterns of polymorphism in genomic regions flanking three highly polymorphic surface antigens in Plasmodium falciparum

scientific article published on 15 December 2007

Plasmodium falciparum: worldwide sequence diversity and evolution of the malaria vaccine candidate merozoite surface protein-2 (MSP-2).

scientific article

Population Genetics and Parasite Diversity

article

Population structure and transmission dynamics of Plasmodium vivax in rural Amazonia.

scientific article published on 6 March 2007

Position-specific polymorphism of Plasmodium falciparum Stuttering motif in a PHISTc PFI1780w

scientific article published on 03 May 2006

Prevalence of positive selection among nearly neutral amino acid replacements in Drosophila

scientific article

Proteostasis Environment Shapes Higher-Order Epistasis Operating on Antibiotic Resistance.

scientific article published on 23 April 2019

Proteostasis environment shapes higher-order epistasis operating on antibiotic resistance

scholarly article published 16 November 2018

Q & A with Daniel L. Hartl, Recipient of the 2019 Thomas Hunt Morgan Medal

scientific article published on 01 June 2019

Rapid evolution of male-biased gene expression in Drosophila

scientific article published on 7 August 2003

Recurrent bottlenecks in the malaria life cycle obscure signals of positive selection

scientific article

Segregation Distortion after Fifteen Years

book chapter by D.L. Hartl and Y. Hiraizumi

Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite

scientific article

Stepwise acquisition of pyrimethamine resistance in the malaria parasite

scientific article published on 08 July 2009

Switching an active site helix in dihydrofolate reductase reveals limits to subdomain modularity

scientific article published in 2021

Temporal constraints on the incorporation of regulatory mutants in evolutionary pathways

scientific article

The evolutionary landscape of antifolate resistance in Plasmodium falciparum ⬇️

scientific article published on August 1, 2011

The origin of malaria: mixed messages from genetic diversity

scientific article published in January 2004

The paradoxical population genetics of Plasmodium falciparum

scientific article

The utility of genomic data for Plasmodium vivax population surveillance

scientific article

Unexpected stability of mariner transgenes in Drosophila

scientific article (publication date: February 2002)

Variable SNP density in aspartyl-protease genes of the malaria parasite Plasmodium falciparum.

scientific article published on 5 April 2006

Paulina is supported by:

About Paulina

Help