List of works by Rhian Touyz

A Four-Dimensional Computational Model of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Measurement of Subtle Blood-Brain Barrier Leakage

scientific article published on 9 October 2020

A Woman With Treatment-Resistant Hypertension

scientific article published on 28 December 2015

A new look at the renin-angiotensin system--focusing on the vascular system

scientific article published on 16 September 2011

ACE2 the Janus-faced protein - from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19

scientific article published on 01 April 2020

Acetaminophen use and risk of myocardial infarction and stroke in a hypertensive cohort

scientific article published on 23 March 2015

Activation of vascular p38MAPK by mechanical stretch is independent of c-Src and NADPH oxidase: influence of hypertension and angiotensin II.

scientific article published on 15 February 2012

Acute ethanol intake induces mitogen-activated protein kinase activation, platelet-derived growth factor receptor phosphorylation, and oxidative stress in resistance arteries

scientific article published on 15 April 2014

Acute ethanol intake induces superoxide anion generation and mitogen-activated protein kinase phosphorylation in rat aorta: a role for angiotensin type 1 receptor

scientific article

Adipocyte Mineralocorticoid Receptor Activation Leads to Metabolic Syndrome and Induction of Prostaglandin D2 Synthase

scientific article published on 11 May 2015

Adipocyte-derived factors regulate vascular smooth muscle cells through mineralocorticoid and glucocorticoid receptors

scientific article published on 25 July 2011

Adipocytes produce aldosterone through calcineurin-dependent signaling pathways: implications in diabetes mellitus-associated obesity and vascular dysfunction

scientific article

Advancement in hypertension pathogenesis: some new concepts

Adventitia-derived hydrogen peroxide impairs relaxation of the rat carotid artery via smooth muscle cell p38 mitogen-activated protein kinase

scientific article

Aldosterone Upregulates Transient Receptor Potential Melastatin 7 (TRPM7).

scientific article published on 27 July 2016

Aldosterone signaling through transient receptor potential melastatin 7 cation channel (TRPM7) and its α-kinase domain

scientific article

Allopurinol initiation and change in blood pressure in older adults with hypertension

scientific article published on 18 August 2014

Altered vascular structure and wave reflection in hypertensive women with low magnesium levels

scientific article published on 2 June 2013

An interaction of renin-angiotensin and kallikrein-kinin systems contributes to vascular hypertrophy in angiotensin II-induced hypertension: in vivo and in vitro studies

scientific article

Angiotensin II and the vascular phenotype in hypertension

scientific article published on 30 March 2011

Angiotensin II and vascular injury

scientific article published on June 2014

Angiotensin II induces Fat1 expression/activation and vascular smooth muscle cell migration via Nox1-dependent reactive oxygen species generation.

scientific article published on January 2014

Angiotensin II signalling and calcineurin in cardiac fibroblasts: differential effects of calcineurin inhibitors FK506 and cyclosporine A.

scientific article

Angiotensin-(1-7) activates a tyrosine phosphatase and inhibits glucose-induced signalling in proximal tubular cells.

scientific article published on 14 January 2009

Arterial Hypertension in Women: State of the Art and Knowledge Gaps

scientific article published in 2023

Cardiac signaling molecules and plasma biomarkers after cardiac transplantation: impact of tacrolimus versus cyclosporine

scientific article published in December 2013

Cardiotoxicity with vascular endothelial growth factor inhibitor therapy

Celebrate World Hypertension Day (WHD) on May 17, 2015, and Contribute to Improving Awareness of Hypertension

article published in 2015

Cell signaling of angiotensin II on vascular tone: novel mechanisms

scientific article published on April 2011

Cellular biomarkers of endothelial health: microparticles, endothelial progenitor cells, and circulating endothelial cells

scientific article published on 09 February 2012

Changes in cardiopulmonary reserve and peripheral arterial function concomitantly with subclinical inflammation and oxidative stress in patients with heart failure with preserved ejection fraction

scientific article published on 27 February 2014

Chemerin Regulates Crosstalk Between Adipocytes and Vascular Cells Through Nox.

scientific article

Chemiluminescence and the Nox1-Nox2-Nox4 Triple Knockout

scientific article published on 9 June 2015

Cholesteryl ester-transfer protein inhibitors stimulate aldosterone biosynthesis in adipocytes through Nox-dependent processes.

scientific article

Clinical practice guidelines for the management of hypertension in the community a statement by the American Society of Hypertension and the International Society of Hypertension

scientific article

Clinical practice guidelines for the management of hypertension in the community: a statement by the American Society of Hypertension and the International Society of Hypertension

scientific article published on 17 December 2013

Combination antihypertensive treatment with aliskiren and blockers of the Renin-Angiotensin system-reassurance but with a note of caution

scientific article published on 29 March 2013

Council for High Blood Pressure Research/InterAmerican Society of Hypertension/International Society of Hypertension: First New Investigators Symposium at the High Blood Pressure Research 2011 Scientific Sessions

scientific article published on 14 November 2011

Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy

scientific article published on 14 July 2010

Crosstalk between adipose tissue and blood vessels in cardiometabolic syndrome: implication of steroid hormone receptors (MR/GR).

scientific article

Differential regulation of Nox1, Nox2 and Nox4 in vascular smooth muscle cells from WKY and SHR.

scientific article published on 17 March 2011

Downregulation of Nuclear Factor Erythroid 2-Related Factor and Associated Antioxidant Genes Contributes to Redox-Sensitive Vascular Dysfunction in Hypertension

scientific journal article

Effects of a domain-selective ACE inhibitor in a mouse model of chronic angiotensin II-dependent hypertension

scientific article published on July 2014

Endothelial Gata5 transcription factor regulates blood pressure

scientific article

Endothelial Microparticle Formation by Angiotensin II Is Mediated via Ang II Receptor Type I/NADPH Oxidase/ Rho Kinase Pathways Targeted to Lipid Rafts

scientific article published on 19 May 2011

Endothelial cells negatively modulate reactive oxygen species generation in vascular smooth muscle cells: role of thioredoxin

scientific article published on 29 June 2009

Ethanol induces vascular relaxation via redox-sensitive and nitric oxide-dependent pathways

scientific article published on 03 December 2011

Ethanol-induced vasoconstriction is mediated via redox-sensitive cyclo-oxygenase-dependent mechanisms

scientific article published on 9 March 2010

Examining the Relationship between Semiquantitative Methods Analysing Concentration-Time and Enhancement-Time Curves from Dynamic-Contrast Enhanced Magnetic Resonance Imaging and Cerebrovascular Dysfunction in Small Vessel Disease

scientific article published on 5 June 2020

Exercise Reverses Metabolic Syndrome in High-Fat Diet-Induced Obese Rats

scientific article published on 01 March 2011

Exercise aggravates cardiovascular risks and mortality in rats with disrupted nitric oxide pathway and treated with recombinant human erythropoietin

scientific article published on 20 January 2011

Exercise training protects against atherosclerotic risk factors through vascular NADPH oxidase, extracellular signal-regulated kinase 1/2 and stress-activated protein kinase/c-Jun N-terminal kinase downregulation in obese rats

scientific article published in February 2015

Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy

scientific article

Global survey of current practice in management of hypertension as reported by societies affiliated with the International Society of Hypertension.

scientific article published in May 2013

Hu antigen R is required for NOX-1 but not NOX-4 regulation by inflammatory stimuli in vascular smooth muscle cells.

scientific article

Human cord blood CD133+ cells exacerbate ischemic acute kidney injury in mice

scientific article published on 4 May 2012

Human endothelial colony-forming cells protect against acute kidney injury: role of exosomes.

scientific article published on 12 June 2015

Hypertension Guidelines

scientific article published on 19 August 2013

Hypertension Guidelines: Effect of Blood Pressure Targets

scientific article published on 21 March 2019

Hypertension due to antiangiogenic cancer therapy with vascular endothelial growth factor inhibitors: understanding and managing a new syndrome.

scientific article published on 25 February 2014

Importance of cholesterol-rich microdomains in the regulation of Nox isoforms and redox signaling in human vascular smooth muscle cells

scientific article published on 20 October 2020

LB01.03: INCIDENCE AND PROGNOSIS OF CANCER ASSOCIATED WITH DIGOXIN AND COMMON ANTIHYPERTENSIVE DRUGS.

scientific article published in June 2015

LB02.06: CLINICAL IMPLICATIONS OF THE DIASTOLIC BLOOD PRESSURE 'J CURVE' IN TREATED HYPERTENSIVE PATIENTS.

scientific article published on June 2015

LB03.07: ANTIHYPERTENSIVE THERAPY AND RISK OF ADMISSIONS FOR MOOD DISORDERS.

scientific article published on June 2015

Linking LOX-1 and arginase II through mitochondria: a novel paradigm in endothelial dysfunction.

scientific article published in August 2014

Loss of Lkb1 in adult beta cells increases beta cell mass and enhances glucose tolerance in mice

scientific article published in October 2009

Lower is better in hypertension, but how low should blood pressure be targeted?

scientific article published on 18 June 2016

Magnesium and Other Biometals in Oxidative Medicine and Redox Biology

scientific article published on 4 October 2017

Mammalian Target of Rapamycin: A Novel Pathway in Vascular Calcification

scientific article published on 05 March 2014

Mechanosensitive regulation of cortactin by p47phox: a new paradigm in cytoskeletal remodeling

scientific article published in June 2013

Metabolic Syndrome Sinkholes: What to Do When Occam's Razor Gets Blunted

scientific article published on 12 January 2015

Microparticles induce cell cycle arrest through redox-sensitive processes in endothelial cells: implications in vascular senescence

scientific article

Microparticles: biomarkers and beyond

scientific article published on April 2013

Mineralocorticoid receptor blockade prevents vascular remodelling in a rodent model of type 2 diabetes mellitus.

scientific article

Moderate Exercise Decreases Inflammation and Oxidative Stress in Hypertension

scientific article published on 19 October 2009

Molecular mechanisms of hypertension--reactive oxygen species and antioxidants: a basic science update for the clinician

scientific article published on 23 March 2012

Molecular mechanisms of hypertension: role of Nox family NADPH oxidases

scientific article published on March 2009

Much Ado about N…atrium: modelling tissue sodium as a highly sensitive marker of subclinical and localized oedema

scientific article published on 13 December 2018

Muscarinic Receptor Type-3 in Hypertension and Cholinergic-Adrenergic Crosstalk: Genetic Insights and Potential for New Antihypertensive Targets

Myocyte growth, repair, and oxidative stress following pediatric heart transplantation

scientific article published on 13 August 2014

NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis

scientific article published on 05 April 2013

NADPH oxidase, NOX1, mediates vascular injury in ischemic retinopathy

scientific article published on 30 October 2013

NOX isoforms and reactive oxygen species in vascular health

scientific article published on February 2011

NOX5: Molecular biology and pathophysiology

scientific article published on 18 March 2019

Nephropathy and elevated BP in mice with podocyte-specific NADPH oxidase 5 expression

scientific article

New insights into mechanisms of hypertension

scientific article published on 01 March 2012

New insights into molecular mechanisms of hypertension

Nicotinamide adenine dinucleotide phosphate reduced oxidase 5 (Nox5) regulation by angiotensin II and endothelin-1 is mediated via calcium/calmodulin-dependent, rac-1-independent pathways in human endothelial cells

scientific article

Notch3 signalling and vascular remodelling in pulmonary arterial hypertension

scientific article published on 01 December 2019

Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling

scientific article

Oxidative stress and human hypertension: vascular mechanisms, biomarkers, and novel therapies

scientific article published on 14 February 2015

Oxidative stress and hypertension: current concepts

scientific article published on April 2010

Oxidative stress, Nox isoforms and complications of diabetes--potential targets for novel therapies

scientific article published on 19 June 2012

Oxidative stress, Noxs, and hypertension: experimental evidence and clinical controversies

scientific article published on June 2012

PARK7/DJ-1 dysregulation by oxidative stress leads to magnesium deficiency: implications in degenerative and chronic diseases

scientific article

PTGER1 deletion attenuates renal injury in diabetic mouse models.

scientific article published on 8 October 2013

Pharmacological inhibition of NOX reduces atherosclerotic lesions, vascular ROS and immune-inflammatory responses in diabetic Apoe(-/-) mice

scientific article published on 30 November 2013

Potentiation of vascular oxidative stress and nitric oxide-mediated endothelial dysfunction by high-fat diet in a mouse model of estrogen deficiency and hyperandrogenemia

scientific article published in September 2009

Progenitor Cells, Bone Marrow–Derived Fibrocytes and Endothelial-to-Mesenchymal Transition

scientific article published on 22 December 2015

Protecting the Heart in Obesity: Role of ACE2 and Its Partners

scientific article published on 01 January 2016

Reactive Oxygen Species Can Provide Atheroprotection via NOX4-Dependent Inhibition of Inflammation and Vascular Remodeling

scientific article published on 29 December 2015

Reactive oxygen species and endothelial function--role of nitric oxide synthase uncoupling and Nox family nicotinamide adenine dinucleotide phosphate oxidases

scientific article published on 28 September 2011

Reactive oxygen species and vascular biology: implications in human hypertension

scientific article published on 28 October 2010

Reactive oxygen species, vascular Noxs, and hypertension: focus on translational and clinical research

scientific article published on 06 June 2013

Receptor and nonreceptor tyrosine kinases in vascular biology of hypertension

scientific article published on March 2010

Redox signaling, Nox5 and vascular remodeling in hypertension

scientific article (publication date: September 2015)

Renal biomarkers

scientific article published on 01 September 2011

Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes.

scientific article

Reply to Letter by McIntyre et al

scientific article published on 07 October 2014

Report of the first International Society of Hypertension (ISH) Trainee/New Investigator Symposium: A Global Hypertension Initiative.

scientific article published in March 2012

Response to European Society of Hypertension and European Society of Cardiology Guidelines and the Muted Enthusiasm for Home Blood Pressure Monitoring

scientific article published on 01 February 2014

Response to the letter regarding the hypothesis paper "Much ado about N…atrium: modelling tissue sodium as a highly sensitive marker of subclinical and localised oedema"

scientific article published on 19 March 2019

Role of angiotensin II type 2 receptor during regression of cardiac hypertrophy in spontaneously hypertensive rats.

scientific article

Role of α1D -adrenoceptors in vascular wall hypertrophy during angiotensin II-induced hypertension.

scientific article published on 4 February 2016

Selective ETA versus dual ETA/B receptor blockade for the prevention of sunitinib-induced hypertension and albuminuria in WKY rats

scientific article published on 08 October 2019

Short daily versus conventional hemodialysis for hypertensive patients: a randomized cross-over study

scientific article

Sphingosine-1-Phosphate-Induced Inflammation Involves Receptor Tyrosine Kinase Transactivation in Vascular Cells

scientific article published on 07 March 2011

Spironolactone treatment attenuates vascular dysfunction in type 2 diabetic mice by decreasing oxidative stress and restoring NO/GC signaling

scientific article

Successes of SPRINT, but Still Some Hurdles to Cross

scientific article

Testosterone induces leucocyte migration by NADPH oxidase-driven ROS- and COX2-dependent mechanisms.

scientific article published in July 2015

Testosterone induces vascular smooth muscle cell migration by NADPH oxidase and c-Src-dependent pathways.

scientific article published on 7 May 2012

The 2007 Canadian Hypertension Education Program recommendations for the management of hypertension: part 1- blood pressure measurement, diagnosis and assessment of risk

scientific article

The 2008 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 1 - blood pressure measurement, diagnosis and assessment of risk

scientific article

The 2009 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 1--blood pressure measurement, diagnosis and assessment of risk

scientific article

The 2009 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 2--therapy

scientific article

The 2010 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2 - therapy

scientific article

The 2010 Canadian Hypertension Education Program recommendations for the management of hypertension: part I - blood pressure measurement, diagnosis and assessment of risk

scientific article

The 2011 Canadian Hypertension Education Program Recommendations for the Management of Hypertension: Blood Pressure Measurement, Diagnosis, Assessment of Risk, and Therapy

article

The 2012 Canadian hypertension education program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy

scientific article published on May 2012

The International Society of Hypertension and World Hypertension League call on governments, nongovernmental organizations and the food industry to work to reduce dietary sodium

scientific article published on February 2014

The Neuroimmune Axis in the Kidney: Role in Hypertension.

scientific article

The World Hypertension League and International Society of Hypertension call on governments, nongovernmental organizations, and the food industry to work to reduce dietary sodium.

scientific article

The effect of angiotensin-(1-7) in mouse unilateral ureteral obstruction

scientific article published on 24 January 2015

Tissue sodium excess is not hypertonic and reflects extracellular volume expansion

scientific article published on 24 August 2020

Urinary podocyte microparticles identify prealbuminuric diabetic glomerular injury

scientific article

Vascular Nox4

scientific article published on 01 April 2012

Vascular Smooth Muscle Cell Differentiation to an Osteogenic Phenotype Involves TRPM7 Modulation by Magnesium

scientific article published on 09 August 2010

Vascular biology of ageing-Implications in hypertension

scientific article

Vascular biology of magnesium and its transporters in hypertension

scientific article published on December 2010

Vascular dysfunction in obese diabetic db/db mice involves the interplay between aldosterone/mineralocorticoid receptor and Rho kinase signaling.

scientific article published on 13 February 2018

Vascular injury in diabetic db/db mice is ameliorated by atorvastatin: role of Rac1/2-sensitive Nox-dependent pathways

scientific article published in April 2015

Vascular proinflammatory responses by aldosterone are mediated via c-Src trafficking to cholesterol-rich microdomains: role of PDGFR.

scientific article

Vascular toxicity associated with anti-angiogenic drugs

scientific article published on 01 September 2020

Vitamin C prevents the endothelial dysfunction induced by acute ethanol intake

scientific article published on 16 September 2015

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