Search filters

List of works by Junko Kurokawa

1,5-benzothiazepine binding domain is located on the extracellular side of the cardiac L-type Ca2+ channel

scientific article published in February 1997

A Combined Approach Using Patch-Clamp Study and Computer Simulation Study for Understanding Long QT Syndrome and TdP in Women

scientific article

A computational model of induced pluripotent stem-cell derived cardiomyocytes for high throughput risk stratification of KCNQ1 genetic variants

scientific article published on 14 August 2020

A computational model of induced pluripotent stem-cell derived cardiomyocytes incorporating experimental variability from multiple data sources

scientific article published on 27 July 2019

A distribution analysis of action potential parameters obtained from patch-clamped human stem cell-derived cardiomyocytes

scientific article published on 21 April 2016

A genetically encoded bioluminescent indicator for the sodium channel activity in living cells

scientific article published in April 2009

A multiscale computational modelling approach predicts mechanisms of female sex risk in the setting of arousal-induced arrhythmias

scientific article

A receptor-independent effect of estrone sulfate on the HERG channel

scientific article

A risk assessment of a common drug using xenograft model

scientific article published on February 2017

Acute effects of oestrogen on the guinea pig and human IKr channels and drug-induced prolongation of cardiac repolarization

scientific article published on 25 April 2008

Acute effects of sex steroid hormones on susceptibility to cardiac arrhythmias: a simulation study

scientific article

Aromatase knockout mice reveal an impact of estrogen on drug-induced alternation of murine electrocardiography parameters

scientific article published on January 2015

Arrhythmic hazard map for a 3D whole-ventricle model under multiple ion channel block

scientific article published on 22 July 2018

Assessment of drug-induced QT prolongation using human iPS cell-derived mature cardiomyocytes

scholarly article by Yasunari Kanda et al published September 2016 in Journal of Pharmacological and Toxicological Methods

Cardiac safety assessment of drugs using three-dimensional heart simulator

scholarly article by Jun-ichi Okada et al published September 2016 in Journal of Pharmacological and Toxicological Methods

Circulating KCNH2 current-activating factor in patients with heart failure and ventricular tachyarrhythmia

scientific article

Clinical, genetic, and electrophysiologic characteristics of a new PAS-domain HERG mutation (M124R) causing Long QT syndrome.

scientific article published in July 2005

Compartmentalized regulations of ion channels in the heart

scientific article published on December 2007

Contractile behaviors of human-induced pluripotent stem cell-derived cardiomyocyte monolayers evaluated with an image-based analysis using motion vector prediction technique: A comparison with extracellular electrophysiology

scholarly article by Tomohiro Hayakawa et al published July 2013 in Journal of Pharmacological and Toxicological Methods

Corrigendum to “Role of transient receptor potential vanilloid 2 in LPS-induced cytokine production in macrophages” [Biochem. Biophys. Res. Commun. 398 (2010) 284–289]

article

Diltiazem derivatives modulate the dihydropyridine-binding to intact rat ventricular myocytes

scientific article published on 01 January 1997

Direct In Vivo Reprogramming with Sendai Virus Vectors Improves Cardiac Function after Myocardial Infarction

scientific article published on 5 December 2017

Disease characterization using LQTS-specific induced pluripotent stem cells

scientific article published on 27 June 2012

Effects of a novel, potent benzothiazepine Ca2+ channel antagonist, DTZ323, on guinea-pig ventricular myocytes

scientific article published on 01 May 1997

Effects of an hERG activator, ICA-105574, on electrophysiological properties of canine hearts

scientific article published on 14 December 2012

Efficient Large-Scale 2D Culture System for Human Induced Pluripotent Stem Cells and Differentiated Cardiomyocytes

scientific article published on 4 October 2017

Electrophysiological consequences of human IKs channel expression in adult murine heart

scientific article published on 19 September 2002

Embryonic type Na+ channel β-subunit, SCN3B masks the disease phenotype of Brugada syndrome

scientific article published on 28 September 2016

Enhancement of Spontaneous Activity by HCN4 Overexpression in Mouse Embryonic Stem Cell-Derived Cardiomyocytes - A Possible Biological Pacemaker

scientific article published on 18 September 2015

Fibroblast Growth Factors and Vascular Endothelial Growth Factor Promote Cardiac Reprogramming under Defined Conditions

scientific article

Ginsenoside Re, a Main Phytosterol of Panax ginseng, Activates Cardiac Potassium Channels via a Nongenomic Pathway of Sex Hormones

scientific article published on 19 September 2006

High-fat diet increases vulnerability to atrial arrhythmia by conduction disturbance via miR-27b

scientific article published on December 2015

Image-based evaluation of contraction-relaxation kinetics of human-induced pluripotent stem cell-derived cardiomyocytes: Correlation and complementarity with extracellular electrophysiology

scientific article published on 23 September 2014

K+ channel structure-activity relationships and mechanisms of drug-induced QT prolongation.

scientific article

KCNE variants reveal a critical role of the beta subunit carboxyl terminus in PKA-dependent regulation of the IKs potassium channel

scientific article

Multi-scale heart simulator, UT-heart is useful for proarrhythmia prediction based on cardiac multi-ion channel data

scholarly article by Takashi Yoshinaga et al published September 2015 in Journal of Pharmacological and Toxicological Methods

Neurohormonal regulation of cardiac ion channels in chronic heart failure

scientific article published on August 2009

New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles: acute effects of female hormones on cardiac ion channels and cardiac repolarization

scientific article published on 07 March 2009

Nitric oxide and cardiac action potential

scientific article published on 01 March 2010

Non-Genomic Regulation of K+ and Ca2+ Channels by Sex Hormones

Non-genomic action of sex steroid hormones and cardiac repolarization

scientific article

Non-genomic regulation of cardiac ion channels by sex hormones

scientific article published on December 2008

Nontranscriptional regulation of cardiac repolarization currents by testosterone

scientific article

Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1.

scientific article

Overexpression of KCNJ2 in induced pluripotent stem cell-derived cardiomyocytes for the assessment of QT-prolonging drugs

scientific article

Overexpression of beta2-adrenergic receptors cAMP-dependent protein kinase phosphorylates and modulates slow delayed rectifier potassium channels expressed in murine heart: evidence for receptor/channel co-localization

scientific article

Oxidative Stress Induced Ventricular Arrhythmia and Impairment of Cardiac Function in Nos1ap Deleted Mice

scientific article published on 09 May 2016

Phosphorylation of the A-kinase-anchoring protein Yotiao contributes to protein kinase A regulation of a heart potassium channel

scientific article

Phytosterol saponin of ginseng (ginsenoside) provides cardiovascular protection as a specific non-genomic ligand of sex hormone receptors

scientific article published on 01 March 2016

Points to consider for a validation study of iPS cell-derived cardiomyocytes using a multi-electrode array system

scientific article published on 28 June 2016

Potassium channel remodeling in cardiac hypertrophy

scientific article published on 7 September 2006

Progesterone regulates cardiac repolarization through a nongenomic pathway: an in vitro patch-clamp and computational modeling study

scientific article

Redox- and calmodulin-dependent S-nitrosylation of the KCNQ1 channel

scientific article published on 5 January 2009

Region- and Condition-Dependence of the Membrane and Ca2+ Clocks in the Sinus Node

scientific article published on 15 December 2011

Regulation of cardiac ion channels via non-genomic action of sex steroid hormones: implication for the gender difference in cardiac arrhythmias

scientific article published on 13 May 2007

Regulatory actions of the A-kinase anchoring protein Yotiao on a heart potassium channel downstream of PKA phosphorylation

scholarly article

Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

scientific article

Requirement of subunit expression for cAMP-mediated regulation of a heart potassium channel

scholarly article

Role of nitric oxide in Ca2+ sensitivity of the slowly activating delayed rectifier K+ current in cardiac myocytes

scientific article published on 29 November 2004

Role of transient receptor potential vanilloid 2 in LPS-induced cytokine production in macrophages

scientific article published on 23 June 2010

Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator

scientific article

Sex and gender aspects in antiarrhythmic therapy

scientific article published on January 2012

Sex hormonal regulation of cardiac ion channels in drug-induced QT syndromes

scientific article

T75M-KCNJ2 mutation causing Andersen-Tawil syndrome enhances inward rectification by changing Mg2+ sensitivity

scientific article published on 18 May 2007

TEA(+)-sensitive KCNQ1 constructs reveal pore-independent access to KCNE1 in assembled I(Ks) channels

scientific article published on January 2001

[Development of mature cardiomyocytes from human iPS cells: toward cardiac safety assessment].

scientific article published in June 2016

[Protein modification of cardiac potassium channels and lethal arrhythmias]

scientific article published on 01 October 2005

Paulina is supported by:

About Paulina

Help