Search filters

List of works by Emmanuel Skordalakes

A Motif in the Vertebrate Telomerase N-Terminal Linker of TERT Contributes to RNA Binding and Telomerase Activity and Processivity

scientific article

A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity

scientific article published on 05 April 2019

A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion

scientific article

ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay

scientific article published on 24 April 2017

Asf1-like structure of the conserved Yaf9 YEATS domain and role in H2A.Z deposition and acetylation

scientific article

Bifunctional peptide boronate inhibitors of thrombin: crystallographic analysis of inhibition enhanced by linkage to an exosite 1 binding peptide

scientific article

Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation

scientific article published on 16 June 2015

Cdc13 N-Terminal Dimerization, DNA Binding, and Telomere Length Regulation

scientific article

Cdc13 OB2 Dimerization Required for Productive Stn1 Binding and Efficient Telomere Maintenance

scientific article

Characterization of a class of peptide boronates with neutral P1 side chains as highly selective inhibitors of thrombin

scientific article published in April 1995

Comparison of proteolytic susceptibility in phosphoglycerate kinases from yeast and E. coli: modulation of conformational ensembles without altering structure or stability

scientific article

Crystallographic Studies of Telomerase

scientific article published on 10 May 2016

Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation

scientific article

Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function

scientific article published on 06 May 2020

Function and Structure of a Prokaryotic Formylglycine-generating Enzyme

scientific article

In vitro reconstitution of the active T. castaneum telomerase

scientific article published on 14 July 2011

Insights into Cdc13 dependent telomere length regulation ⬇️

scientific article published on October 1, 2010

Interaction between TBP and Condensin Drives the Organization and Faithful Segregation of Mitotic Chromosomes

scientific article

LIMD2 is a small LIM-only protein overexpressed in metastatic lesions that regulates cell motility and tumor progression by directly binding to and activating the integrin-linked kinase

scientific article

Neural and synaptic defects in slytherin, a zebrafish model for human congenital disorders of glycosylation

scientific article

Pol α-primase dependent nuclear localization of the mammalian CST complex

scientific article published on 17 March 2021

Recent advances with cyclin-dependent kinase inhibitors: therapeutic agents for breast cancer and their role in immuno-oncology

scientific article published on 20 June 2019

SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase

scientific article

Single cell analysis of RNA-mediated histone H3.3 recruitment to a cytomegalovirus promoter-regulated transcription site.

scientific article

Structural Analysis Reveals the Deleterious Effects of Telomerase Mutations in Bone Marrow Failure Syndromes.

scientific article

Structural Basis of Telomerase Inhibition by the Highly Specific BIBR1532

scientific article published on 6 September 2015

Structural and functional analysis of an OB-fold in human Ctc1 implicated in telomere maintenance and bone marrow syndromes

scientific article published on 8 December 2017

Structural and functional analysis of the human POT1-TPP1 telomeric complex

scientific article

Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA

scientific article

Structural insights into RNA-dependent ring closure and ATPase activation by the Rho termination factor

scientific article published in November 2006

Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic bicyclomycin

scientific article published in January 2005

Structure and Function of the Conserved Core of Histone Deposition Protein Asf1

Structure and function of the conserved core of histone deposition protein Asf1

scientific article

Structure and function of the telomeric CST complex

scientific article

Structure of the Human Telomeric Stn1-Ten1 Capping Complex

scientific article

Structure of the RNA-binding domain of telomerase: implications for RNA recognition and binding

scientific article

Structure of the Rho transcription terminator: mechanism of mRNA recognition and helicase loading

scientific article

Structure of the Tribolium castaneum telomerase catalytic subunit TERT

scientific article

Telomerase and the benefits of healthy living.

scientific article

Telomerase structure function.

scientific article published on 17 December 2010

Telomerase structure paves the way for new cancer therapies.

scientific article published on March 2009

The Telomere Binding Protein Cdc13 and the Single-Stranded DNA Binding Protein RPA Protect Telomeric DNA from Resection by Exonucleases

scientific article published on 8 August 2015

Paulina is supported by:

About Paulina

Help