List of works - Philippe Desprès

Rhizophora mucronata Lam., a halophyte from Mauritius Island, inhibits the entry of Zika virus in human cells (A549)- an in vitro and in silico analysis

scientific article published in 2023

A Chimeric Zika Virus between Viral Strains MR766 and BeH819015 Highlights a Role for E-glycan Loop in Antibody-mediated Virus Neutralization

scientific article published on 24 June 2019

A High-Performance Multiplex Immunoassay for Serodiagnosis of Flavivirus-Associated Neurological Diseases in Horses

scientific article

A Japanese encephalitis virus genotype 5 molecular clone is highly neuropathogenic in a mouse model: impact of the structural protein region on virulence

scientific article published on 18 March 2015

A Lentiviral Vector Expressing Japanese Encephalitis Virus-like Particles Elicits Broad Neutralizing Antibody Response in Pigs

scientific article published on 5 October 2015

A Single Amino Acid Substitution in the M Protein Attenuates Japanese Encephalitis Virus in Mammalian Hosts

scientific article

A Viperin Mutant Bearing the K358R Substitution Lost its Anti-ZIKA Virus Activity ⬇️

scientific article published on 29 March 2019

A fatal neuroinvasive West Nile virus infection in a traveler returning from Madagascar: clinical, epidemiological and veterinary investigations

scientific article published on 10 June 2013

A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease

scientific article

A nonsense mutation in the gene encoding 2'-5'-oligoadenylate synthetase/L1 isoform is associated with West Nile virus susceptibility in laboratory mice

scientific article

A paediatric vaccination vector based on live attenuated measles vaccine

scientific article

A phenotypic assay to identify Chikungunya virus inhibitors targeting the nonstructural protein nsP2.

scientific article

A recombinant measles vaccine expressing chikungunya virus-like particles is strongly immunogenic and protects mice from lethal challenge with chikungunya virus

scientific article published on 4 June 2013

A robust method for the rapid generation of recombinant Zika virus expressing the GFP reporter gene

scientific article published on 26 July 2016

A single immunization with a minute dose of a lentiviral vector-based vaccine is highly effective at eliciting protective humoral immunity against West Nile virus

scientific article

A variant in the CD209 promoter is associated with severity of dengue disease

scientific article

Antiviral Effect of Stenocline ericoides DC. and Stenocline inuloides DC., Two Flavonoid-Rich Endemic Plants from Madagascar, against Dengue and Zika Viruses

scientific article published in 2022

Apoptosis during ZIKA Virus Infection: Too Soon or Too Late?

scientific article published on 26 January 2022

Ayapana triplinervis Essential Oil and Its Main Component Thymohydroquinone Dimethyl Ether Inhibit Zika Virus at Doses Devoid of Toxicity in Zebrafish

scientific article published on 23 September 2019

Biology of Zika Virus Infection in Human Skin Cells

scientific article

Bioluminescent Ross River Virus Allows Live Monitoring of Acute and Long-Term Alphaviral Infection by In Vivo Imaging

scientific article published on 27 June 2019

Bruguiera gymnorhiza (L.) Lam. at the Forefront of Pharma to Confront Zika Virus and Microbial Infections—An In Vitro and In Silico Perspective

scientific article published in 2021

CHOP Pro-Apoptotic Transcriptional Program in Response to ER Stress Is Hacked by Zika Virus

scientific article published in 2021

CHRONOVAC VOYAGEUR: A study of the immune response to yellow fever vaccine among infants previously immunized against measles

scientific article published on 25 September 2017

Capture-recapture method for estimating annual incidence of imported dengue, France, 2007-2010.

scientific article

Characterization of reemerging chikungunya virus

scientific article published in June 2007

Chikungunya Virus, Southeastern France ⬇️

scientific article published on May 1, 2011

Chikungunya virus envelope-specific human monoclonal antibodies with broad neutralization potency

scientific article

Circulation of Zoonotic Arboviruses in Equine Populations of Mallorca Island (Spain).

scientific article published on 27 March 2017

Class II ADP-ribosylation factors are required for efficient secretion of dengue viruses

scientific article

ClearColi BL21(DE3)-based expression of Zika virus antigens illustrates a rapid method of antibody production against emerging pathogens

scientific article published on 20 September 2017

Comparative analysis of viral RNA signatures on different RIG-I-like receptors

scientific article

Correction: Haddad, J.G., et al. Doratoxylon apetalum, an Indigenous Medicinal Plant from Mascarene Islands, Is a Potent Inhibitor of Zika and Dengue Virus Infection in Human Cells Int. J. Mol. Sci. 2019, 20, 2382

scientific article published on 22 October 2020

Cranberry Pomace Extract Exerts Antiviral Activity against Zika and Dengue Virus at Safe Doses for Adult Zebrafish

scientific article published in 2022

DNA vaccines expressing retrovirus-like particles are efficient immunogens to induce neutralizing antibodies

scientific article

Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals

scientific article

Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses

scientific article

Dengue virus M and E proteins belonging to genotype II (Cosmopolitan) of serotype 2 are influenced by the nature of M residue 36

scientific article published in 2023

Dengue virus M protein contains a proapoptotic sequence referred to as ApoptoM.

scientific article published on October 2003

Dengue virus activates membrane TRAIL relocalization and IFN-α production by human plasmacytoid dendritic cells in vitro and in vivo.

scientific article

Dengue virus replication in infected human keratinocytes leads to activation of antiviral innate immune responses

scientific article published on 21 June 2011

Dengue: a growing threat requiring vaccine development for disease prevention

article

Dermal-Type Macrophages Expressing CD209/DC-SIGN Show Inherent Resistance to Dengue Virus Growth

scientific article

Dynamics of immune cell recruitment during West Nile encephalitis and identification of a new CD19+B220-BST-2+ leukocyte population

scientific article

European Aedes albopictus and Culex pipiens Are Competent Vectors for Japanese Encephalitis Virus

scientific article

Evidence of RedOX Imbalance during Zika Virus Infection Promoting the Formation of Disulfide-Bond-Dependent Oligomers of the Envelope Protein

scientific article published in 2022

Extracellular Vesicles Are Conveyors of the NS1 Toxin during Dengue Virus and Zika Virus Infection

scientific article published in 2023

Extract from Aphloia theiformis, an edible indigenous plant from Reunion Island, impairs Zika virus attachment to the host cell surface

scientific article published on 18 July 2018

Genome analysis of dengue type-1 virus isolated between 1990 and 2001 in Brazil reveals a remarkable conservation of the structural proteins but amino acid differences in the non-structural proteins

scientific article published on December 2002

Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak

scientific article

Guillain-Barré Syndrome Outbreak Associated With Zika Virus Infection in French Polynesia

scientific article published in August 2016

Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study

scientific article

High-throughput screening for broad-spectrum chemical inhibitors of RNA viruses

scientific article

Human keratinocytes restrict chikungunya virus replication at a post-fusion step

scientific article published on 8 December 2014

Human muscle satellite cells as targets of Chikungunya virus infection

scientific article

IS-98-ST1 West Nile virus derived from an infectious cDNA clone retains neuroinvasiveness and neurovirulence properties of the original virus

scientific article

Immune Reactivity of a 20-mer Peptide Representing the Zika E Glycan Loop Involves the Antigenic Determinants E-152/156/158

scientific article published on 05 November 2020

Immunogenicity, safety, and tolerability of a recombinant measles-virus-based chikungunya vaccine: a randomised, double-blind, placebo-controlled, active-comparator, first-in-man trial

scientific article

In vitro comparison of three common essential oils mosquito repellents as inhibitors of the Ross River virus.

scientific article

Infection of mouse neurones by West Nile virus is modulated by the interferon-inducible 2'-5' oligoadenylate synthetase 1b protein

scientific article published on June 2003

Inflammasome signaling pathways exert antiviral effect against Chikungunya virus in human dermal fibroblasts

scientific article published on 4 April 2015

Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein

scientific article

Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity

scientific article (publication date: 2013)

Innate immune responses to dengue virus

scientific article

Instability of the NS1 Glycoprotein from La Reunion 2018 Dengue 2 Virus (Cosmopolitan-1 Genotype) in Huh7 Cells Is Due to Lysine Residues on Positions 272 and 324

scientific article published in 2021

Live measles vaccine expressing the secreted form of the West Nile virus envelope glycoprotein protects against West Nile virus encephalitis

scientific article published on 10 December 2004

Mapping of Chikungunya virus interactions with host proteins identified nsP2 as a highly connected viral component

scientific article published on 18 January 2012

Measles Vaccine Expressing the Secreted Form of West Nile Virus Envelope Glycoprotein Induces Protective Immunity in Squirrel Monkeys, a New Model of West Nile Virus Infection ⬇️

scientific article published on May 2, 2012

Mechanisms of dengue virus-induced cell death

scientific article published on January 2003

NKp44 Receptor Mediates Interaction of the Envelope Glycoproteins from the West Nile and Dengue Viruses with NK Cells

scientific article (publication date: 15 August 2009)

Neutralization of Japanese Encephalitis Virus by heme-induced broadly reactive human monoclonal antibody

scientific article

New evidence for endemic circulation of Ross River Virus in the Pacific Islands and the potential for emergence

scientific article (publication date: February 2017)

New insights on the neuropathology of West Nile virus

scientific article published on April 2004

Papaya Fruit Pulp and Resulting Lactic Fermented Pulp Exert Antiviral Activity against Zika Virus

scientific article published on 20 August 2020

Pediatric Measles Vaccine Expressing a Dengue Antigen Induces Durable Serotype-specific Neutralizing Antibodies to Dengue Virus

scientific article (publication date: 12 December 2007)

Pediatric measles vaccine expressing a dengue tetravalent antigen elicits neutralizing antibodies against all four dengue viruses ⬇️

scientific article published on August 3, 2010

PredictSNP2: A Unified Platform for Accurately Evaluating SNP Effects by Exploiting the Different Characteristics of Variants in Distinct Genomic Regions.

scientific article

Probing Molecular Insights into Zika Virus⁻Host Interactions

scientific article

Production and characterization of mouse monoclonal antibodies reactive to Chikungunya envelope E2 glycoprotein

scientific article

Protective Antiviral Immunity Conferred by a Nonintegrative Lentiviral Vector-Based Vaccine

scientific article (publication date: 2008)

Recognition determinants of broadly neutralizing human antibodies against dengue viruses

scientific article

Recombinant Zika NS1 Protein Secreted from Vero Cells Is Efficient for Inducing Production of Immune Serum Directed against NS1 Dimer

scientific article published on 23 December 2017

Rift valley fever in humans and animals in Mayotte, an endemic situation?

scientific article

Role of skin immune cells on the host susceptibility to mosquito-borne viruses

scientific article

Ross River Virus Seroprevalence, French Polynesia, 2014-2015.

scientific article published on October 2017

Serological Diagnosis of Flavivirus-Associated Human Infections

scientific article published on 14 May 2020

Seroprevalence of Dengue and Chikungunya Virus Antibodies, French Polynesia, 2014-2015.

scientific article published in March 2018

Seroprevalence of arboviruses among blood donors in French Polynesia, 2011–2013

scientific article

Silent Circulation of Ross River Virus in French Polynesia

scientific article published on 15 June 2015

Subversion of the Heme Oxygenase-1 Antiviral Activity by Zika Virus

scientific article published on 20 December 2018

Tackling dengue fever: Current status and challenges

scientific article

The 2',5'-oligoadenylate synthetase 1b is a potent inhibitor of West Nile virus replication inside infected cells

scientific journal article

The E glycoprotein plays an essential role in the high pathogenicity of European-Mediterranean IS98 strain of West Nile virus

scientific article

The E2-E166K substitution restores Chikungunya virus growth in OAS3 expressing cells by acting on viral entry

scientific article published on 11 August 2012

The Envelope Residues E152/156/158 of Zika Virus Influence the Early Stages of Virus Infection in Human Cells

scientific article published on 15 November 2019

The Flavonoid Isoquercitrin Precludes Initiation of Zika Virus Infection in Human Cells.

scientific article

The Geraniin-Rich Extract from Reunion Island Endemic Medicinal Plant Phyllanthus phillyreifolius Inhibits Zika and Dengue Virus Infection at Non-Toxic Effect Doses in Zebrafish

scientific article published on 15 May 2020

The Israeli strain IS-98-ST1 of West Nile virus as viral model for West Nile encephalitis in the Old World

scientific article

The Roles of prM-E Proteins in Historical and Epidemic Zika Virus-mediated Infection and Neurocytotoxicity

scientific article published on 14 February 2019

The South Pacific epidemic strain of Zika virus replicates efficiently in human epithelial A549 cells leading to IFN-β production and apoptosis induction

scientific article

The ZIKA Virus Delays Cell Death Through the Anti-Apoptotic Bcl-2 Family Proteins

scientific article published on 29 October 2019

The interaction of flavivirus M protein with light chain Tctex-1 of human dynein plays a role in late stages of virus replication

scientific article

The large form of human 2',5'-Oligoadenylate Synthetase (OAS3) exerts antiviral effect against Chikungunya virus

scientific article

The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities

scientific article

The structural proteins of epidemic and historical strains of Zika virus differ in their ability to initiate viral infection in human host cells

scientific article published on 30 January 2018

Transgenic expression of full-length 2′,5′-oligoadenylate synthetase 1b confers to BALB/c mice resistance against West Nile virus-induced encephalitis ⬇️

scientific article published on June 17, 2011

Two Chikungunya isolates from the outbreak of La Reunion (Indian Ocean) exhibit different patterns of infection in the mosquito, Aedes albopictus

scientific article published in 2007

Use of Envelope Domain III Protein for the Detection of IgG Type Antibodies Specific to Zika Virus by Indirect ELISA

scientific article published in 2023

Validating plastic scintillation detectors for photon dosimetry in the radiologic energy range

scientific article

Viral determinants in the NS3 helicase and 2K peptide that promote West Nile virus resistance to antiviral action of 2',5'-oligoadenylate synthetase 1b.

scientific article published on 25 January 2010

Viral entry route determines how human plasmacytoid dendritic cells produce type I interferons

scientific article published on 3 March 2015

West Nile virus and its emergence in the United States of America

scientific article

Yellow fever vaccine attenuation revealed: loss of diversity

scientific article published on 17 October 2013

Zika E Glycan Loop Region and Guillain–Barré Syndrome-Related Proteins: A Possible Molecular Mimicry to Be Taken in Account for Vaccine Development

scientific article published in 2021

Zika M Oligopeptide ZAMP Confers Cell Death-Promoting Capability to a Soluble Tumor-Associated Antigen through Caspase-3/7 Activation

scientific article published on 16 December 2020

Zika Virus Growth in Human Kidney Cells Is Restricted by an Elevated Glucose Level

scientific article published in 2021

Zika Virus Seroprevalence, French Polynesia, 2014–2015

scientific article (publication date: April 2017)

Zika rash and increased risk of congenital brain abnormalities

scientific article published on 13 January 2017

Zika virus: epidemiology, clinical features and host-virus interactions

scientific article

an Indigenous Medicinal Plant from Mascarene Islands, Is a Potent Inhibitor of Zika and Dengue Virus Infection in Human Cells

scientific article published on 14 May 2019

List of works by Philippe Desprès

<i>Rhizophora mucronata</i> Lam., a halophyte from Mauritius Island, inhibits the entry of Zika virus in human cells (A549)- an <i>in vitro</i> and <i>in silico</i> analysis

A Chimeric Zika Virus between Viral Strains MR766 and BeH819015 Highlights a Role for E-glycan Loop in Antibody-mediated Virus Neutralization

A High-Performance Multiplex Immunoassay for Serodiagnosis of Flavivirus-Associated Neurological Diseases in Horses

A Japanese encephalitis virus genotype 5 molecular clone is highly neuropathogenic in a mouse model: impact of the structural protein region on virulence

A Lentiviral Vector Expressing Japanese Encephalitis Virus-like Particles Elicits Broad Neutralizing Antibody Response in Pigs

A Single Amino Acid Substitution in the M Protein Attenuates Japanese Encephalitis Virus in Mammalian Hosts

A Viperin Mutant Bearing the K358R Substitution Lost its Anti-ZIKA Virus Activity ⬇️

A fatal neuroinvasive West Nile virus infection in a traveler returning from Madagascar: clinical, epidemiological and veterinary investigations

A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease

A nonsense mutation in the gene encoding 2'-5'-oligoadenylate synthetase/L1 isoform is associated with West Nile virus susceptibility in laboratory mice

A paediatric vaccination vector based on live attenuated measles vaccine

A phenotypic assay to identify Chikungunya virus inhibitors targeting the nonstructural protein nsP2.

A recombinant measles vaccine expressing chikungunya virus-like particles is strongly immunogenic and protects mice from lethal challenge with chikungunya virus

A robust method for the rapid generation of recombinant Zika virus expressing the GFP reporter gene

A single immunization with a minute dose of a lentiviral vector-based vaccine is highly effective at eliciting protective humoral immunity against West Nile virus

A variant in the CD209 promoter is associated with severity of dengue disease

Antiviral Effect of Stenocline ericoides DC. and Stenocline inuloides DC., Two Flavonoid-Rich Endemic Plants from Madagascar, against Dengue and Zika Viruses

Apoptosis during ZIKA Virus Infection: Too Soon or Too Late?

Ayapana triplinervis Essential Oil and Its Main Component Thymohydroquinone Dimethyl Ether Inhibit Zika Virus at Doses Devoid of Toxicity in Zebrafish

Biology of Zika Virus Infection in Human Skin Cells

Bioluminescent Ross River Virus Allows Live Monitoring of Acute and Long-Term Alphaviral Infection by In Vivo Imaging

Bruguiera gymnorhiza (L.) Lam. at the Forefront of Pharma to Confront Zika Virus and Microbial Infections—An In Vitro and In Silico Perspective

CHOP Pro-Apoptotic Transcriptional Program in Response to ER Stress Is Hacked by Zika Virus

CHRONOVAC VOYAGEUR: A study of the immune response to yellow fever vaccine among infants previously immunized against measles

Capture-recapture method for estimating annual incidence of imported dengue, France, 2007-2010.

Characterization of reemerging chikungunya virus

Chikungunya Virus, Southeastern France ⬇️

Chikungunya virus envelope-specific human monoclonal antibodies with broad neutralization potency

Circulation of Zoonotic Arboviruses in Equine Populations of Mallorca Island (Spain).

Class II ADP-ribosylation factors are required for efficient secretion of dengue viruses

ClearColi BL21(DE3)-based expression of Zika virus antigens illustrates a rapid method of antibody production against emerging pathogens

Comparative analysis of viral RNA signatures on different RIG-I-like receptors

Correction: Haddad, J.G., et al. Doratoxylon apetalum, an Indigenous Medicinal Plant from Mascarene Islands, Is a Potent Inhibitor of Zika and Dengue Virus Infection in Human Cells Int. J. Mol. Sci. 2019, 20, 2382

Cranberry Pomace Extract Exerts Antiviral Activity against Zika and Dengue Virus at Safe Doses for Adult Zebrafish

DNA vaccines expressing retrovirus-like particles are efficient immunogens to induce neutralizing antibodies

Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN)-mediated enhancement of dengue virus infection is independent of DC-SIGN internalization signals

Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses

Dengue virus M and E proteins belonging to genotype II (Cosmopolitan) of serotype 2 are influenced by the nature of M residue 36

Dengue virus M protein contains a proapoptotic sequence referred to as ApoptoM.

Dengue virus activates membrane TRAIL relocalization and IFN-α production by human plasmacytoid dendritic cells in vitro and in vivo.

Dengue virus replication in infected human keratinocytes leads to activation of antiviral innate immune responses

Dengue: a growing threat requiring vaccine development for disease prevention

Dermal-Type Macrophages Expressing CD209/DC-SIGN Show Inherent Resistance to Dengue Virus Growth

Dynamics of immune cell recruitment during West Nile encephalitis and identification of a new CD19+B220-BST-2+ leukocyte population

European Aedes albopictus and Culex pipiens Are Competent Vectors for Japanese Encephalitis Virus

Evidence of RedOX Imbalance during Zika Virus Infection Promoting the Formation of Disulfide-Bond-Dependent Oligomers of the Envelope Protein

Extracellular Vesicles Are Conveyors of the NS1 Toxin during Dengue Virus and Zika Virus Infection

Extract from Aphloia theiformis, an edible indigenous plant from Reunion Island, impairs Zika virus attachment to the host cell surface

Genome analysis of dengue type-1 virus isolated between 1990 and 2001 in Brazil reveals a remarkable conservation of the structural proteins but amino acid differences in the non-structural proteins

Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak

Guillain-Barré Syndrome Outbreak Associated With Zika Virus Infection in French Polynesia

Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study

High-throughput screening for broad-spectrum chemical inhibitors of RNA viruses

Human keratinocytes restrict chikungunya virus replication at a post-fusion step

Human muscle satellite cells as targets of Chikungunya virus infection

IS-98-ST1 West Nile virus derived from an infectious cDNA clone retains neuroinvasiveness and neurovirulence properties of the original virus

Immune Reactivity of a 20-mer Peptide Representing the Zika E Glycan Loop Involves the Antigenic Determinants E-152/156/158

Immunogenicity, safety, and tolerability of a recombinant measles-virus-based chikungunya vaccine: a randomised, double-blind, placebo-controlled, active-comparator, first-in-man trial

In vitro comparison of three common essential oils mosquito repellents as inhibitors of the Ross River virus.

Infection of mouse neurones by West Nile virus is modulated by the interferon-inducible 2'-5' oligoadenylate synthetase 1b protein

Inflammasome signaling pathways exert antiviral effect against Chikungunya virus in human dermal fibroblasts

Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein

Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity

Innate immune responses to dengue virus

Instability of the NS1 Glycoprotein from La Reunion 2018 Dengue 2 Virus (Cosmopolitan-1 Genotype) in Huh7 Cells Is Due to Lysine Residues on Positions 272 and 324

Live measles vaccine expressing the secreted form of the West Nile virus envelope glycoprotein protects against West Nile virus encephalitis

Mapping of Chikungunya virus interactions with host proteins identified nsP2 as a highly connected viral component

Measles Vaccine Expressing the Secreted Form of West Nile Virus Envelope Glycoprotein Induces Protective Immunity in Squirrel Monkeys, a New Model of West Nile Virus Infection ⬇️

Mechanisms of dengue virus-induced cell death

NKp44 Receptor Mediates Interaction of the Envelope Glycoproteins from the West Nile and Dengue Viruses with NK Cells

Neutralization of Japanese Encephalitis Virus by heme-induced broadly reactive human monoclonal antibody

New evidence for endemic circulation of Ross River Virus in the Pacific Islands and the potential for emergence

New insights on the neuropathology of West Nile virus

Papaya Fruit Pulp and Resulting Lactic Fermented Pulp Exert Antiviral Activity against Zika Virus

Pediatric Measles Vaccine Expressing a Dengue Antigen Induces Durable Serotype-specific Neutralizing Antibodies to Dengue Virus

Pediatric measles vaccine expressing a dengue tetravalent antigen elicits neutralizing antibodies against all four dengue viruses ⬇️

PredictSNP2: A Unified Platform for Accurately Evaluating SNP Effects by Exploiting the Different Characteristics of Variants in Distinct Genomic Regions.

Probing Molecular Insights into Zika Virus⁻Host Interactions

Production and characterization of mouse monoclonal antibodies reactive to Chikungunya envelope E2 glycoprotein