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List of works by Michael S. Diamond

2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo

scientific article

2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members

scientific journal article

A CRISPR screen defines a signal peptide processing pathway required by flaviviruses

scientific article

A Critical Role for Induced IgM in the Protection against West Nile Virus Infection

scientific article

A Library of Infectious Hepatitis C Viruses with Engineered Mutations in the E2 Gene Reveals Growth-Adaptive Mutations That Modulate Interactions with Scavenger Receptor Class B Type I.

scientific article

A Mouse Model of Zika Virus Pathogenesis

scientific article

A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection

scientific article published on 26 June 2020

A Role for Ifit2 in Restricting West Nile Virus Infection in the Brain ⬇️

scientific article published on 05 June 2013

A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2

scientific article published on 19 August 2020

A Therapeutic Antibody against West Nile Virus Neutralizes Infection by Blocking Fusion within Endosomes

scientific article (publication date: May 2009)

A cross-protective mAb recognizes a novel epitope within the flavivirus NS1 protein ⬇️

scientific article published on September 14, 2011

A cross-reactive antibody protects against Ross River virus musculoskeletal disease despite rapid neutralization escape in mice

scientific article published on 06 August 2020

A fusion-loop antibody enhances the infectious properties of immature flavivirus particles

scientific article published on 31 August 2011

A game of numbers: the stoichiometry of antibody-mediated neutralization of flavivirus infection

scientific article published on December 2014

A genetic basis for human susceptibility to West Nile virus.

scientific article

A human antibody against Zika virus crosslinks the E protein to prevent infection

scientific article (publication date: 16 March 2017)

A hydrogen peroxide-inactivated virus vaccine elicits humoral and cellular immunity and protects against lethal West Nile virus infection in aged mice

scientific article published on 5 December 2012

A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection

scientific article published on 01 May 2019

A molecular understanding of alphavirus entry

scientific article published on 22 October 2020

A novel T-cell receptor mimic defines dendritic cells that present an immunodominant West Nile virus epitope in mice

scientific article

A novel computer algorithm improves antibody epitope prediction using affinity-selected mimotopes: a case study using monoclonal antibodies against the West Nile virus E protein

scientific article published on 29 August 2008

A protective Zika virus E-dimer-based subunit vaccine engineered to abrogate antibody-dependent enhancement of dengue infection

scientific article published on 02 September 2019

A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions

scientific article published on 19 November 2018

A rapid and quantitative assay for measuring antibody-mediated neutralization of West Nile virus infection

scientific article published on 2 December 2005

A short N-terminal peptide motif on flavivirus nonstructural protein NS1 modulates cellular targeting and immune recognition

scientific article published on 30 June 2010

A short hairpin RNA screen of interferon-stimulated genes identifies a novel negative regulator of the cellular antiviral response

scientific article published on 18 June 2013

A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis

scientific article (publication date: 16 February 2017)

A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage

scientific article published on 22 September 2017

A temporal role of type I interferon signaling in CD8+ T cell maturation during acute West Nile virus infection

scientific article published on December 2011

A tetravalent dengue nanoparticle stimulates antibody production in mice

scientific article published on 22 March 2012

A viral RNA structural element alters host recognition of nonself RNA

scientific article

AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity

scientific article published on 28 June 2016

AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses

scientific article (publication date: 6 February 2017)

Actively replicating West Nile virus is resistant to cytoplasmic delivery of siRNA.

scientific article

After the pandemic: perspectives on the future trajectory of COVID-19

scientific article published in 2021

Age-Dependent Cell Trafficking Defects in Draining Lymph Nodes Impair Adaptive Immunity and Control of West Nile Virus Infection

scientific article

Alpha/beta interferon protects against lethal West Nile virus infection by restricting cellular tropism and enhancing neuronal survival

scientific article

An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis

scientific article published on 18 February 2020

An IRF-3-, IRF-5-, and IRF-7-Independent Pathway of Dengue Viral Resistance Utilizes IRF-1 to Stimulate Type I and II Interferon Responses

scientific article published in November 2017

An Immunocompetent Mouse Model of Zika Virus Infection.

scientific article published in May 2018

An infectious West Nile virus that expresses a GFP reporter gene.

scientific article published on March 2005

An mRNA Vaccine Protects Mice against Multiple Tick-Transmitted Flavivirus Infections

An ultrasensitive electrogenerated chemiluminescence-based immunoassay for specific detection of Zika virus

scientific article

Animal Models of Zika Virus Infection during Pregnancy

scholarly article by Elizabeth A Caine et al published 31 October 2018 in Viruses

Animal Models of Zika Virus Infection, Pathogenesis, and Immunity

scientific article

Antagonism of the complement component C4 by flavivirus nonstructural protein NS1.

scientific article

Antibodies against West Nile Virus Nonstructural Protein NS1 Prevent Lethal Infection through Fc   Receptor-Dependent and -Independent Mechanisms

scientific article

Antibodies against the envelope glycoprotein promote infectivity of immature dengue virus serotype 2

scientific article

Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy

scientific article published on 19 October 2020

Antibody Recognition and Neutralization Determinants on Domains I and II of West Nile Virus Envelope Protein

scientific article

Antibody Recognition of Cell Surface-Associated NS1 Triggers Fc- Receptor-Mediated Phagocytosis and Clearance of West Nile Virus-Infected Cells

scientific article

Antibody Response to Hypervariable Region 1 Interferes with Broadly Neutralizing Antibodies to Hepatitis C Virus

scientific article published on 6 January 2016

Antibody prophylaxis and therapy against West Nile virus infection in wild-type and immunodeficient mice

scientific article published on December 2003

Antibody responses in humans infected with newly emerging strains of West Nile Virus in Europe

scientific article

Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects

scientific article published on 27 February 2017

Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement

scientific article published on 01 August 2018

Antigen-specific cytotoxic T lymphocytes protect against lethal West Nile virus encephalitis.

scientific article

Author Correction: Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection

scientific article published on 01 March 2020

Axonal transport mediates West Nile virus entry into the central nervous system and induces acute flaccid paralysis

scientific article (publication date: 23 October 2007)

B cells and antibody play critical roles in the immediate defense of disseminated infection by West Nile encephalitis virus.

scientific article

Barrier-to-Autointegration Factor 1 Protects against a Basal cGAS-STING Response

scientific article published on 10 March 2020

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

scientific article (publication date: 14 November 2008)

Beta interferon controls West Nile virus infection and pathogenesis in mice

scientific article published on 4 May 2011

Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins ⬇️

scientific article

Binding of flavivirus nonstructural protein NS1 to C4b binding protein modulates complement activation

scientific article

Broadly Neutralizing Activity of Zika Virus-Immune Sera Identifies a Single Viral Serotype ⬇️

scientific article

Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress

scientific article

CD4+ T-Cell Responses Are Required for Clearance of West Nile Virus from the Central Nervous System

scientific article

CD40-CD40 Ligand Interactions Promote Trafficking of CD8+ T Cells into the Brain and Protection against West Nile Virus Encephalitis

scientific article

CD8+ T Cells Require Perforin To Clear West Nile Virus from Infected Neurons

scientific article

CD8+ T cells use TRAIL to restrict West Nile virus pathogenesis by controlling infection in neurons

scientific article published on 27 June 2012

CXCR3 mediates region-specific antiviral T cell trafficking within the central nervous system during West Nile virus encephalitis

scientific article

CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis

scientific article

Capturing a Flavivirus Pre-Fusion Intermediate

scientific article (publication date: November 2009)

Caspase 3-Dependent Cell Death of Neurons Contributes to the Pathogenesis of West Nile Virus Encephalitis

scientific article (publication date: March 2007)

Castanospermine, a potent inhibitor of dengue virus infection in vitro and in vivo

scientific article

Cell-Specific IRF-3 Responses Protect against West Nile Virus Infection by Interferon-Dependent and -Independent Mechanisms

scientific article (publication date: 27 July 2007)

Cell-intrinsic innate immune control of West Nile virus infection

scientific article

Cellular and Humoral Immunity Protect against Vaginal Zika Virus Infection in Mice

scientific article published on 17 January 2018

Chikungunya viral arthritis in the United States: a mimic of seronegative rheumatoid arthritis

scientific article

Chikungunya virus evades antiviral CD8+ T cell responses to establish persistent infection in joint-associated tissues

scientific article published on 26 February 2020

Chikungunya virus infection results in higher and persistent viral replication in aged rhesus macaques due to defects in anti-viral immunity

scientific article

Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes

scientific article

Chronic joint disease caused by persistent Chikungunya virus infection is controlled by the adaptive immune response

scientific article

Clearance of Chikungunya Virus Infection in Lymphoid Tissues Is Promoted by Treatment with an Agonistic Anti-CD137 Antibody

scientific article published on 26 November 2019

Cleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinase

scientific article (publication date: 15 January 2006)

Commensal microbes and interferon-λ determine persistence of enteric murine norovirus infection

scientific article

Complement Protein C1q Inhibits Antibody-Dependent Enhancement of Flavivirus Infection in an IgG Subclass-Specific Manner

scientific article

Complement Protein C1q Reduces the Stoichiometric Threshold for Antibody-Mediated Neutralization of West Nile Virus

scientific article (publication date: 22 October 2009)

Complement activation is required for induction of a protective antibody response against West Nile virus infection

scientific article

Complement and its role in protection and pathogenesis of flavivirus infections

scientific article (publication date: 30 December 2008)

Complement modulates pathogenesis and antibody-dependent neutralization of West Nile virus infection through a C5-independent mechanism

scientific article

Complement-mediated neutralization of dengue virus requires mannose-binding lectin

scientific article published on 13 December 2011

Complex phenotypes in mosquitoes and mice associated with neutralization escape of a Dengue virus type 1 monoclonal antibody

scientific article published on 9 March 2012

Consumptive coagulopathy of severe yellow fever occurs independently of hepatocellular tropism and massive hepatic injury

scientific article published on 02 December 2020

Correction: In-Depth Analysis of the Antibody Response of Individuals Exposed to Primary Dengue Virus Infection

Correction: Therapeutic Efficacy of Antibodies Lacking Fc. Receptor Binding against Lethal Dengue Virus Infection Is Due to Neutralizing Potency and Blocking of Enhancing Antibodies.

scientific article published on 27 March 2013

Correction: Zika virus has oncolytic activity against glioblastoma stem cells

scientific article published on 15 September 2017

Corrigendum to “Human antibodies against dengue enhance dengue viral infectivity without suppressing type I interferon secretion in primary human monocytes” [Virology 410 (2011) 240–247]

scholarly article by Zhihua Kou published in May 2011

Corrigendum: Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

scientific article published on 8 July 2015

Critical role for interferon regulatory factor 3 (IRF-3) and IRF-7 in type I interferon-mediated control of murine norovirus replication

scientific article

Cross-reactive Dengue virus-specific CD8 T cells protect against Zika virus during pregnancy

scientific article published in Nature Communications

Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions

scientific article published on 20 December 2020

Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor

scientific article published on 09 May 2019

Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization

scientific article published on 01 December 2018

Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity

scientific article

Crystal Structure of the West Nile Virus Envelope Glycoprotein

scientific article (publication date: December 2006)

Cutting edge: independent roles for IRF-3 and IRF-7 in hematopoietic and nonhematopoietic cells during host response to Chikungunya infection

scientific article

De novo design of picomolar SARS-CoV-2 miniprotein inhibitors

scientific article published on 09 September 2020

Deficient IFN signaling by myeloid cells leads to MAVS-dependent virus-induced sepsis

scientific article

Defining Limits of Treatment with Humanized Neutralizing Monoclonal Antibody for West Nile Virus Neurological Infection in a Hamster Model

scientific article

Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection

scientific article

Defining the levels of secreted non-structural protein NS1 after West Nile virus infection in cell culture and mice

scientific article (publication date: March 2008)

Defining the risk of SARS-CoV-2 variants on immune protection

scientific article published on 31 March 2022

Degrees of maturity: the complex structure and biology of flaviviruses ⬇️

scientific article published on March 23, 2012

Dendritic cells in dengue virus infection: targets of virus replication and mediators of immunity

scientific article

Dengue Antibodies, then Zika: A Fatal Sequence in Mice

scientific article

Dengue Virus Immunopathogenesis: Lessons Applicable to the Emergence of Zika Virus

scientific article

Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice

scientific article published on 5 February 2019

Dengue structure differs at the temperatures of its human and mosquito hosts

scientific article

Dengue virus neutralization is modulated by IgG antibody subclass and Fcγ receptor subtype

scientific article

Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge

scientific article published on 13 November 2017

Dermal and muscle fibroblasts and skeletal myofibers survive chikungunya virus infection and harbor persistent RNA

scientific article published on 29 August 2019

Development and characterization of non-glycosylated E and NS1 mutant viruses as a potential candidate vaccine for West Nile virus

scientific article published on 5 November 2009

Development of Resistance to Passive Therapy with a Potently Neutralizing Humanized Monoclonal Antibody against West Nile Virus

scientific article

Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus

scientific article (publication date: 2013)

Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus

scientific article

Development of effective therapies against West Nile virus infection

scientific article

Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses

scientific article published on 3 March 2013

Differential replication of pathogenic and nonpathogenic strains of West Nile virus within astrocytes

scientific article

Direct complement restriction of flavivirus infection requires glycan recognition by mannose-binding lectin

scientific article

Distinct Roles of Interferon Alpha and Beta in Controlling Chikungunya Virus Replication and Modulating Neutrophil-Mediated Inflammation

scientific article published on 12 December 2019

Distinguishing West Nile virus infection using a recombinant envelope protein with mutations in the conserved fusion-loop

scientific article

Early B-Cell Activation after West Nile Virus Infection Requires Alpha/Beta Interferon but Not Antigen Receptor Signaling

scientific article

Ebola images emerge from the cave

scientific article published on August 2008

Editorial overview: Viral pathogenesis: Strategies for virus survival - Acute versus persistent infections

scientific article published in April 2017

Efficacy of a T Cell-Biased Adenovirus Vector as a Zika Virus Vaccine

scientific article published in Scientific Reports

Endogenous MHC-related protein 1 is transiently expressed on the plasma membrane in a conformation that activates mucosal-associated invariant T cells

scientific article published on 14 March 2011

Engineered Dengue Virus Domain III Proteins Elicit Cross-Neutralizing Antibody Responses in Mice

article

Enhancement of anti-DIII antibodies by the C3d derivative P28 results in lower viral titers and augments protection in mice

scientific article

Enhancing dengue virus maturation using a stable furin over-expressing cell line

scientific article published on 12 July 2016

Enveloped viruses disable innate immune responses in dendritic cells by direct activation of TAM receptors

scientific article published on August 2013

Evasion of innate and adaptive immunity by flaviviruses

scientific article (publication date: June 2003)

Evidence for a genetic and physical interaction between nonstructural proteins NS1 and NS4B that modulates replication of West Nile virus

scientific article

Experimental infection of rhesus macaques and common marmosets with a European strain of West Nile virus

scientific article

Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19

scientific article published on 07 October 2020

Fas Ligand Interactions Contribute to CD8+ T-Cell-Mediated Control of West Nile Virus Infection in the Central Nervous System

scientific article (publication date: November 2007)

Feasibility of cross-protective vaccination against flaviviruses of the Japanese encephalitis serocomplex ⬇️

scientific article published on February 1, 2012

Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate

scientific article published on 12 September 2016

Functional analysis of antibodies against dengue virus type 4 reveals strain-dependent epitope exposure that impacts neutralization and protection

scientific article published on 19 June 2013

Fusion loop peptide of the West Nile virus envelope protein is essential for pathogenesis and is recognized by a therapeutic cross-reactive human monoclonal antibody

scientific article published on 17 June 2009

GPR18 Controls Reconstitution of Mouse Small Intestine Intraepithelial Lymphocytes following Bone Marrow Transplantation ⬇️

scientific article published on 21 July 2015

Gamma Interferon Plays a Crucial Early Antiviral Role in Protection against West Nile Virus Infection

scientific article

Generation and analysis of novel plant-derived antibody-based therapeutic molecules against West Nile virus

scientific article

Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail

scientific article published on 21 September 2021

Genome-wide RNAi screen identifies broadly-acting host factors that inhibit arbovirus infection

scientific article

Genotype-specific neutralization and protection by antibodies against dengue virus type 3.

scientific article published on 11 August 2010

Gestational Stage and IFN-λ Signaling Regulate ZIKV Infection In Utero

scientific article published on September 2017

Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors

scientific article published on 27 February 2015

Hepatitis C Virus Infection Upregulates CD55 Expression on the Hepatocyte Surface and Promotes Association with Virus Particles ⬇️

scientific article published on 08 May 2013

Hepatitis C virus RNA replication depends on specific cis- and trans-acting activities of viral nonstructural proteins

scientific article (publication date: April 2015)

Hepatitis C virus epitope exposure and neutralization by antibodies is affected by time and temperature

scientific article

Herpesvirus latency confers symbiotic protection from bacterial infection

scientific article

Host restriction factor screening: let the virus do the work

scientific article

Human IFIT3 Modulates IFIT1 RNA Binding Specificity and Protein Stability

scientific article published on 7 March 2018

Human Monoclonal Antibodies against NS1 Protein Protect against Lethal West Nile Virus Infection

scientific article published on 12 October 2021

Human Monoclonal Antibodies against West Nile Virus Induced by Natural Infection Neutralize at a Postattachment Step

scientific article (publication date: July 2009)

Human antibodies against dengue enhance dengue viral infectivity without suppressing type I interferon secretion in primary human monocytes

scientific article published on 4 December 2010

Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection

scientific article published on 25 September 2017

Human memory T cells with a naive phenotype accumulate with aging and respond to persistent viruses

scientific article published on 06 June 2016

Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease

scientific article published on 04 May 2020

Human monoclonal antibodies against chikungunya virus target multiple distinct epitopes in the E1 and E2 glycoproteins.

scientific article published on 7 November 2019

Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions and monocytes for optimal therapeutic protection

scientific article published on 28 December 2020

Humanized monoclonal antibody against West Nile virus envelope protein administered after neuronal infection protects against lethal encephalitis in hamsters.

scientific article published on 22 September 2006

Hydrogen–deuterium exchange mass spectrometry identifies spatially distinct antibody epitopes on domain III of the Zika virus envelope protein

scientific article published in 2020

IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes Induction of Type I Interferon

scientific article published on 30 April 2015

IFIT1: A dual sensor and effector molecule that detects non-2'-O methylated viral RNA and inhibits its translation

scientific article

IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells

scientific article published on 04 November 2020

IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

scientific article published on 24 June 2012

IMM-BCP-01, a patient-derived anti–SARS-CoV-2 antibody cocktail, is active across variants of concern including Omicron BA.1 and BA.2

scientific article published in 2022

IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

scientific article

IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling

scientific article

Identification of Novel Small-Molecule Inhibitors of West Nile Virus Infection

scientific article

Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions

scientific article

Identifying Candidate Targets of Immune Responses in Zika Virus Based on Homology to Epitopes in Other Flavivirus Species

scientific article (publication date: 15 November 2016)

Immune Responses to West Nile Virus Infection in the Central Nervous System ⬇️

scientific article published on December 17, 2012

Immune responses at the maternal-fetal interface

scientific article published on 01 January 2019

Immune-Mediated Protection and Pathogenesis of Chikungunya Virus

scientific article published on December 2016

Immunodominant West Nile Virus T Cell Epitopes Are Fewer in Number and Fashionably Late

scientific article published on 20 April 2016

Immunological headgear: antiviral immune responses protect against neuroinvasive West Nile virus

scientific article published on 06 June 2008

In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection

scientific article

Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection

scientific article

Induction of Epitope-Specific Neutralizing Antibodies against West Nile Virus

scientific article (publication date: November 2007)

Induction of IFN-β and the Innate Antiviral Response in Myeloid Cells Occurs through an IPS-1-Dependent Signal That Does Not Require IRF-3 and IRF-7

scientific article (publication date: October 2009)

Infection and injury of neurons by West Nile encephalitis virus

scientific article published on December 2003

Infiltrating monocytes drive cardiac dysfunction in a cardiomyocyte-restricted mouse model of SARS-CoV-2 infection

scientific article published in 2024

Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication.

scientific article published on 27 September 2017

Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs

scientific article published on 24 August 2020

Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2

scientific article published on 06 August 2020

Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice

scientific article published on 10 July 2017

Inhibitor of κB kinase epsilon (IKK(epsilon)), STAT1, and IFIT2 proteins define novel innate immune effector pathway against West Nile virus infection

scientific article published on 7 November 2011

Inhibitor of κB kinase ϵ (IKKϵ), STAT1, and IFIT2 proteins define novel innate immune effector pathway against West Nile virus infection.

scientific article published in February 2012

Innate and Adaptive Immune Responses Determine Protection against Disseminated Infection by West Nile Encephalitis Virus ⬇️

scientific article published on January 1, 2003

Innate immune escape by Dengue and West Nile viruses

scientific article published on 25 October 2016

Innate immune interactions within the central nervous system modulate pathogenesis of viral infections

scientific article

Innate immune restriction and antagonism of viral RNA lacking 2׳-O methylation

scientific article

Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics

scientific article published on 03 August 2020

Interferon Regulatory Factor IRF-7 Induces the Antiviral Alpha Interferon Response and Protects against Lethal West Nile Virus Infection

scientific article

Interferon lambda protects the female reproductive tract against Zika virus infection

scientific article published in Nature Communications

Interferon regulatory factor 5-dependent immune responses in the draining lymph node protect against West Nile virus infection

scientific article

Interferon regulatory factor-1 (IRF-1) protects against chikungunya virus induced immunopathology by restricting infection in muscle cells

scientific article published on 23 August 2017

Interferon regulatory factor-1 (IRF-1) shapes both innate and CD8(+) T cell immune responses against West Nile virus infection

scientific journal article

Interferon-Regulatory Factor 5-Dependent Signaling Restricts Orthobunyavirus Dissemination to the Central Nervous System

scientific article

Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis

scientific article

Interferon-λ cures persistent murine norovirus infection in the absence of adaptive immunity

scientific article

Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier

scientific article published on April 2015

Interferon-λ: Immune Functions at Barrier Surfaces and Beyond

scientific article (publication date: 21 July 2015)

Intestinal Dysmotility Syndromes following Systemic Infection by Flaviviruses

scientific article published on 04 October 2018

Irg1 expression in myeloid cells prevents immunopathology during M. tuberculosis infection

scientific article published on 06 March 2018

Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus

scientific article published in July 2015

Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus

scientific article published in 2015

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation

scientific article published on 28 June 2016

K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5.

scientific article published on 26 January 2014

LDLRAD3 is a receptor for Venezuelan equine encephalitis virus

scientific article published on 18 November 2020

Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification

scientific article (publication date: February 2010)

Levels of Circulating NS1 Impact West Nile Virus Spread to the Brain

scientific article published on 04 August 2021

Listeria exploits IFITM3 to suppress antibacterial activity in phagocytes

scientific article published on 17 August 2021

Loss of DAP12 and FcRγ drives exaggerated IL-12 production and CD8(+) T cell response by CCR2(+) Mo-DCs

scientific article

MAVS Expressed by Hematopoietic Cells Is Critical for Control of West Nile Virus Infection and Pathogenesis

scientific article published on 25 May 2016

MAVS is essential for primary CD4+ T cell immunity but not for recall T cell responses following an attenuated West Nile virus infection

scientific article (publication date: 11 January 2017)

MDA5 and autoimmune disease

scientific article

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

scientific article published on 16 January 2017

MUTATIONS IN THE E2 GLYCOPROTEIN AND THE 3' UNTRANSLATED REGION ENHANCE CHIKUNGUNYA VIRUS VIRULENCE IN MICE.

scientific article

Mapping and Role of the CD8+ T Cell Response During Primary Zika Virus Infection in Mice

scientific article (publication date: 2017)

Maternal-Fetal Transmission of Zika Virus: Routes and Signals for Infection

scientific article (publication date: 12 April 2017)

Maternally Acquired Zika Antibodies Enhance Dengue Disease Severity in Mice

article

Matrix-M™ adjuvanted envelope protein vaccine protects against lethal lineage 1 and 2 West Nile virus infection in mice

scientific article published on 28 December 2013

Maturation of West Nile Virus Modulates Sensitivity to Antibody-Mediated Neutralization

scientific article (publication date: 9 May 2008)

Measure and countermeasure: type I IFN (IFN-alpha/beta) antiviral response against West Nile virus

scientific article published on 24 June 2009

Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge

scientific article published on 01 February 2020

Mechanisms of Zika Virus Infection and Neuropathogenesis

scientific article

Mechanisms of evasion of the type I interferon antiviral response by flaviviruses

scientific article

Mechanisms of restriction of viral neuroinvasion at the blood-brain barrier

scientific article

Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants ⬇️

scientific article published on December 12, 2011

Modeling Zika Virus Infection in Pregnancy

scientific article

Modified mRNA Vaccines Protect against Zika Virus Infection

scientific article published on 16 February 2017

Modified mRNA Vaccines Protect against Zika Virus Infection

scientific article published on March 2017

Molecular Insight into Dengue Virus Pathogenesis and Its Implications for Disease Control

scientific article

Molecular mechanisms of antibody-mediated neutralisation of flavivirus infection

scientific article

Monoclonal antibody produced in plants efficiently treats West Nile virus infection in mice

scientific article (publication date: 9 February 2010)

Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617

scientific article published on 28 March 2022

Mosquito Bite Delivery of Dengue Virus Enhances Immunogenicity and Pathogenesis in Humanized Mice ⬇️

scientific article published on May 9, 2012

Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus

scientific article

Mutations of an antibody binding energy hot spot on domain III of the dengue 2 envelope glycoprotein exploited for neutralization escape

scientific article published on 15 September 2010

Mxra8 is a receptor for multiple arthritogenic alphaviruses

scientific article published in Nature

Mycophenolic acid inhibits dengue virus infection by preventing replication of viral RNA.

scientific article

N-linked glycosylation of dengue virus NS1 protein modulates secretion, cell-surface expression, hexamer stability, and interactions with human complement ⬇️

scientific article published on March 22, 2011

Negative regulators of the RIG-I-like receptor signaling pathway

scientific article published on 10 March 2017

Neuronal CXCL10 directs CD8+ T-cell recruitment and control of West Nile virus encephalitis

scientific article

Neurotropic arboviruses induce interferon regulatory factor 3-mediated neuronal responses that are cytoprotective, interferon independent, and inhibited by Western equine encephalitis virus capsid

scientific article published on 28 November 2012

Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354 ⬇️

scientific article published on October 18, 2010

Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis

scientific article

Neutralizing antibodies against Mayaro virus require Fc effector functions for protective activity

scientific article published on 23 July 2019

Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice

scientific article published on 7 November 2016

Neutralizing monoclonal antibodies against hepatitis C virus E2 protein bind discontinuous epitopes and inhibit infection at a postattachment step

scientific article

New insights into innate immune restriction of West Nile virus infection

scientific article

No IL-18BP? Avoid HAV

scientific article published on 26 June 2019

Non-structural protein-1 is required for West Nile virus replication complex formation and viral RNA synthesis

scientific article

Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma

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On a mouse monoclonal antibody that neutralizes all four dengue virus serotypes

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Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcγR interaction on monocytes

scientific article published on 01 February 2019

Oral Antibiotic Treatment of Mice Exacerbates the Disease Severity of Multiple Flavivirus Infections

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Oropouche virus infection and pathogenesis are restricted by MAVS, IRF-3, IRF-7, and type I interferon signaling pathways in nonmyeloid cells

scientific article

Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene

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PKR and RNase L Contribute to Protection against Lethal West Nile Virus Infection by Controlling Early Viral Spread in the Periphery and Replication in Neurons

scientific article (publication date: July 2006)

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

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Pathogenesis of West Nile Virus Infection: a Balance between Virulence, Innate and Adaptive Immunity, and Viral Evasion

scientific article

Pathogenesis of flavivirus encephalitis

scientific article published on January 2003

Pathogenic Chikungunya Virus Evades B Cell Responses to Establish Persistence

scientific article published on 20 July 2016

Pattern recognition receptor MDA5 modulates CD8+ T cell-dependent clearance of West Nile virus from the central nervous system

scientific article published on 21 August 2013

Plasmodium falciparum Histidine-Rich Protein II Compromises Brain Endothelial Barriers and May Promote Cerebral Malaria Pathogenesis

scientific article published on 07 June 2016

Plasmodium falciparum histidine-rich protein II causes vascular leakage and exacerbates experimental cerebral malaria in mice

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Poorly neutralizing cross-reactive antibodies against the fusion loop of West Nile virus envelope protein protect in vivo via Fcgamma receptor and complement-dependent effector mechanisms

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Potent dengue virus neutralization by a therapeutic antibody with low monovalent affinity requires bivalent engagement

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Potently neutralizing and protective human antibodies against SARS-CoV-2

scientific article published on 15 July 2020

Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals

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Pre-clinical development of a hydrogen peroxide-inactivated West Nile virus vaccine

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Preparing for the Next Epidemic with Basic Virology

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Progress on the development of therapeutics against West Nile virus

scientific article (publication date: September 2009)

Propagation, quantification, detection, and storage of West Nile virus

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Protection by immunoglobulin dual-affinity retargeting antibodies against dengue virus

scientific article published on 8 May 2013

Protection of mice deficient in mature B cells from West Nile virus infection by passive and active immunization

scientific article published on 27 November 2017

Protective Efficacy of Nucleic Acid Vaccines Against Transmission of Zika Virus During Pregnancy in Mice

scientific article published on 01 October 2019

Protective and therapeutic capacity of human single-chain Fv-Fc fusion proteins against West Nile virus

scientific article

Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein

scientific article published on 19 November 2018

Protective immune responses against West Nile virus are primed by distinct complement activation pathways

scientific article

Publisher Correction: SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function

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RIG-I Signaling Is Essential for Influenza B Virus-Induced Rapid Interferon Gene Expression

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RNA sensor-induced type I IFN prevents diabetes caused by a β cell-tropic virus in mice

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Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection

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Resistance to Alpha/Beta Interferon Is a Determinant of West Nile Virus Replication Fitness and Virulence

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Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

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Robust production of virus-like particles and monoclonal antibodies with geminiviral replicon vectors in lettuce

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S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3.

scientific article

SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function

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Secreted NS1 Protects Dengue Virus from Mannose-Binding Lectin-Mediated Neutralization

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Secreted NS1 of Dengue Virus Attaches to the Surface of Cells via Interactions with Heparan Sulfate and Chondroitin Sulfate E

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Selective Blockade of Interferon-α and -β Reveals Their Non-Redundant Functions in a Mouse Model of West Nile Virus Infection

scientific article published on 26 May 2015

Sensitive population profiling and genome assembly of HIV and Flaviviruses using ultra-deep sequencing technologies.

scientific article published on 11 October 2010

Single-chain HLA-A2 MHC trimers that incorporate an immundominant peptide elicit protective T cell immunity against lethal West Nile virus infection

scientific article published on 8 March 2010

Six RNA Viruses and Forty-One Hosts: Viral Small RNAs and Modulation of Small RNA Repertoires in Vertebrate and Invertebrate Systems

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Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses

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Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope

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Structural Basis of Zika Virus-Specific Antibody Protection

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Structural Insights into the Mechanisms of Antibody-Mediated Neutralization of Flavivirus Infection: Implications for Vaccine Development

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Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization ⬇️

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Structural and functional characterization of an anti-West Nile virus monoclonal antibody and its single-chain variant produced in glycoengineered plants

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Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody

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Structural basis of Chikungunya virus inhibition by monoclonal antibodies

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Structural basis of Flavivirus NS1 assembly and antibody recognition

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Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope

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Structural study of the C-terminal domain of non-structural protein 1 from Japanese encephalitis virus.

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Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2.

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Structure and intracellular targeting of the SARS-coronavirus Orf7a accessory protein

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Structure of acidic pH dengue virus showing the fusogenic glycoprotein trimers

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Structure, expression, and intracellular localization of the SARS-CoV accessory proteins 7a and 7b.

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TAM Receptors Are Not Required for Zika Virus Infection in Mice

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TNF-alpha-dependent regulation of CXCR3 expression modulates neuronal survival during West Nile virus encephalitis

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The 5' and 3' ends of alphavirus RNAs--Non-coding is not non-functional

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The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1

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The FDA-approved drug sofosbuvir inhibits Zika virus infection

scientific article (publication date: November 2016)

The Fc region of an antibody impacts the neutralization of West Nile viruses in different maturation states

scientific article published on 09 October 2013

The Immune Adaptor Molecule SARM Modulates Tumor Necrosis Factor Alpha Production and Microglia Activation in the Brainstem and Restricts West Nile Virus Pathogenesis

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The Interferon-Induced Exonuclease ISG20 Exerts Antiviral Activity through Upregulation of Type I Interferon Response Proteins

scientific article published on 19 September 2018

The Interferon-Stimulated Gene IFITM3 Restricts Infection and Pathogenesis of Arthritogenic and Encephalitic Alphaviruses

scientific article published on 20 July 2016

The Interferon-Stimulated Gene Ifi27l2a Restricts West Nile Virus Infection and Pathogenesis in a Cell-Type- and Region-Specific Manner

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The RIG-I-like receptor LGP2 controls CD8(+) T cell survival and fitness

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The SARS-CoV-2 B.1.1.529 Omicron virus causes attenuated infection and disease in mice and hamsters

The Stoichiometry of Antibody-Mediated Neutralization and Enhancement of West Nile Virus Infection

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The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity

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The broad-spectrum antiviral functions of IFIT and IFITM proteins

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The continued threat of emerging flaviviruses

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The emergence of Zika virus and its new clinical syndromes

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The essential, nonredundant roles of RIG-I and MDA5 in detecting and controlling West Nile virus infection

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The host immunologic response to West Nile encephalitis virus

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The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity

scientific article published on September 2010

The innate immune adaptor molecule MyD88 restricts West Nile virus replication and spread in neurons of the central nervous system

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The interferon-inducible gene viperin restricts West Nile virus pathogenesis

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The interferon-stimulated gene IFITM3 restricts West Nile virus infection and pathogenesis

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The lectin pathway of complement activation contributes to protection from West Nile virus infection

scientific article published on 26 January 2011

The low-density lipoprotein receptor promotes infection of multiple encephalitic alphaviruses

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The molecular basis of antibody-mediated neutralization of West Nile virus

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The naturally attenuated Kunjin strain of West Nile virus shows enhanced sensitivity to the host type I interferon response

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The potent and broadly neutralizing human dengue virus-specific monoclonal antibody 1C19 reveals a unique cross-reactive epitope on the bc loop of domain II of the envelope protein

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The relative contribution of antibody and CD8+ T cells to vaccine immunity against West Nile encephalitis virus

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The structural immunology of antibody protection against West Nile virus

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The transmembrane domain of the severe acute respiratory syndrome coronavirus ORF7b protein is necessary and sufficient for its retention in the Golgi complex

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The utility of siRNA transcripts produced by RNA polymerase i in down regulating viral gene expression and replication of negative- and positive-strand RNA viruses

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Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques

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Therapeutic efficacy of antibodies lacking Fcγ receptor binding against lethal dengue virus infection is due to neutralizing potency and blocking of enhancing antibodies [corrected].

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Therapeutic efficacy of favipiravir against Bourbon virus in mice.

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Thermodynamically coupled biosensors for detecting neutralizing antibodies against SARS-CoV-2 variants

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Toll-Like Receptor 3 Has a Protective Role against West Nile Virus Infection

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Translation efficiency determines differences in cellular infection among dengue virus type 2 strains

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Tregs control the development of symptomatic West Nile virus infection in humans and mice

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Tumor Necrosis Factor Alpha Protects against Lethal West Nile Virus Infection by Promoting Trafficking of Mononuclear Leukocytes into the Central Nervous System

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Type- and Subcomplex-Specific Neutralizing Antibodies against Domain III of Dengue Virus Type 2 Envelope Protein Recognize Adjacent Epitopes

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Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms

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Understanding How Zika Virus Enters and Infects Neural Target Cells

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Utilization of an Eilat Virus-Based Chimera for Serological Detection of Chikungunya Infection

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Vaccination of mice using the West Nile virus E-protein in a DNA prime-protein boost strategy stimulates cell-mediated immunity and protects mice against a lethal challenge

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Vaccination strategies against Zika virus

scientific article (publication date: April 2017)

Vaccine Development as a Means to Control Dengue Virus Pathogenesis: Do We Know Enough?

scientific article published on 27 June 2014

Vaccine Mediated Protection Against Zika Virus-Induced Congenital Disease

scientific article published on July 2017

Vaccine-induced protection of rhesus macaques against plasma viremia after intradermal infection with a European lineage 1 strain of West Nile virus

scientific article (publication date: 2014)

Vaccines in 2017: Closing in on a Zika virus vaccine

scientific article published on 4 December 2017

Virus and Host Determinants of West Nile Virus Pathogenesis

scientific article (publication date: June 2009)

WDFY4 is required for cross-presentation in response to viral and tumor antigens

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West Nile virus in complex with the Fab fragment of a neutralizing monoclonal antibody

scientific article (publication date: 15 August 2006)

West Nile virus infection and immunity

scientific article published on February 2013

West Nile virus noncoding subgenomic RNA contributes to viral evasion of the type I interferon-mediated antiviral response

scientific article

West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H

scientific article (publication date: 12 December 2006)

West Nile virus. II. Immunopathophysiology in humans

scientific article published on 28 April 2011

West Nile virus: crossing the blood-brain barrier

scientific article published on December 2004

West Nile virus–induced acute flaccid paralysis is prevented by monoclonal antibody treatment when administered after infection of spinal cord neurons

scientific article (publication date: April 2008)

Zika Virus Causes Acute Infection and Inflammation in the Ovary of Mice Without Apparent Defects in Fertility

scientific article published on 01 November 2019

Zika Virus Causes Acute and Chronic Prostatitis in Mice and Macaques

scientific article published on 01 April 2020

Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise

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Zika Virus Infection in Mice Causes Panuveitis with Shedding of Virus in Tears

scientific article (publication date: 20 September 2016)

Zika Virus NS3 Mimics a Cellular 14-3-3-Binding Motif to Antagonize RIG-I- and MDA5-Mediated Innate Immunity

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Zika Virus Pathogenesis and Tissue Tropism

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Zika Virus Vaccine Development: Progress in the Face of New Challenges

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Zika Virus: New Clinical Syndromes and Its Emergence in the Western Hemisphere

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Zika virus has oncolytic activity against glioblastoma stem cells

scientific article published on 5 September 2017

Zika virus infection damages the testes in mice ⬇️

scientific article published on 31 October 2016

Zika virus vaccines: immune response, current status, and future challenges.

scientific article published on 9 May 2018

Zika virus-related neurotropic flaviviruses infect human placental explants and cause fetal demise in mice

scientific article published in January 2018

c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells

scientific article

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