List of works - Arnon Lavie

A Conserved Surface Loop in Type I Dehydroquinate Dehydratases Positions an Active Site Arginine and Functions in Substrate Binding

scientific article

Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure

scientific article

Crystal Structures of Type I Dehydroquinate Dehydratase in Complex with Quinate and Shikimate Suggest a Novel Mechanism of Schiff Base Formation

scientific article

Crystal structure of a type II dehydroquinate dehydratase-like protein from Bifidobacterium longum

scientific article

Development of New Deoxycytidine Kinase Inhibitors and Noninvasive in Vivo Evaluation Using Positron Emission Tomography

scientific article

Domain Swapping within PDZ2 Is Responsible for Dimerization of ZO Proteins

scientific article

Elucidation of different binding modes of purine nucleosides to human deoxycytidine kinase

scientific article

Elucidation of the Active Conformation of the APS-Kinase Domain of Human PAPS Synthetase 1

scientific article

Elucidation of the Specific Function of the Conserved Threonine Triad Responsible for Human l-Asparaginase Autocleavage and Substrate Hydrolysis

scientific article

Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase

scientific article

Free Glycine Accelerates the Autoproteolytic Activation of Human Asparaginase

scientific article

Insights into Regulated Ligand Binding Sites from the Structure of ZO-1 Src Homology 3-Guanylate Kinase Module

scientific article

Insights into the Mechanism of Type I Dehydroquinate Dehydratases from Structures of Reaction Intermediates

scientific article

Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues

scientific article

Nonenantioselectivity property of human deoxycytidine kinase explained by structures of the enzyme in complex with L- and D-nucleosides

scientific article

Quaternary Structure Change as a Mechanism for the Regulation of Thymidine Kinase 1-Like Enzymes

scientific article

Reassessing the type I dehydroquinate dehydratase catalytic triad: Kinetic and structural studies of Glu86 mutants

scientific article

Structural and Kinetic Characterization of Guinea Pig l -Asparaginase Type III

scientific article

Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues

scientific article

Structural basis for L27 domain-mediated assembly of signaling and cell polarity complexes

scientific article

Structural basis for nucleotide-dependent regulation of membrane-associated guanylate kinase-like domains

scientific article

Structural basis for substrate promiscuity of dCK

scientific article

Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases

scientific article

Structural characterization of new deoxycytidine kinase inhibitors rationalizes the affinity-determining moieties of the molecules

scientific article

Structural characterization of the closed conformation of mouse guanylate kinase

scientific article

Structural mechanism for substrate inhibition of the adenosine 5'-phosphosulfate kinase domain of human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 and its ramifications for enzyme regulation

scientific article

Structure and Mutagenesis of Neural Cell Adhesion Molecule Domains: EVIDENCE FOR FLEXIBILITY IN THE PLACEMENT OF POLYSIALIC ACID ATTACHMENT SITES

scientific article

Structure of human dCK suggests strategies to improve anticancer and antiviral therapy

scientific article

Structures of Apo and Product-Bound Human l -Asparaginase: Insights into the Mechanism of Autoproteolysis and Substrate Hydrolysis

scientific article

Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds

scientific article (publication date: 11 March 2003)

The Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1

scientific article

The sugar ring of the nucleoside is required for productive substrate positioning in the active site of human deoxycytidine kinase (dCK): implications for the development of dCK-activated acyclic guanine analogues

scientific article

List of works by Arnon Lavie

A Conserved Surface Loop in Type I Dehydroquinate Dehydratases Positions an Active Site Arginine and Functions in Substrate Binding

Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure

Crystal Structures of Type I Dehydroquinate Dehydratase in Complex with Quinate and Shikimate Suggest a Novel Mechanism of Schiff Base Formation

Crystal structure of a type II dehydroquinate dehydratase-like protein from Bifidobacterium longum

Development of New Deoxycytidine Kinase Inhibitors and Noninvasive in Vivo Evaluation Using Positron Emission Tomography

Domain Swapping within PDZ2 Is Responsible for Dimerization of ZO Proteins

Elucidation of different binding modes of purine nucleosides to human deoxycytidine kinase

Elucidation of the Active Conformation of the APS-Kinase Domain of Human PAPS Synthetase 1

Elucidation of the Specific Function of the Conserved Threonine Triad Responsible for Human l-Asparaginase Autocleavage and Substrate Hydrolysis

Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase

Free Glycine Accelerates the Autoproteolytic Activation of Human Asparaginase

Insights into Regulated Ligand Binding Sites from the Structure of ZO-1 Src Homology 3-Guanylate Kinase Module

Insights into the Mechanism of Type I Dehydroquinate Dehydratases from Structures of Reaction Intermediates

Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues

Nonenantioselectivity property of human deoxycytidine kinase explained by structures of the enzyme in complex with L- and D-nucleosides

Quaternary Structure Change as a Mechanism for the Regulation of Thymidine Kinase 1-Like Enzymes

Reassessing the type I dehydroquinate dehydratase catalytic triad: Kinetic and structural studies of Glu86 mutants

Structural and Kinetic Characterization of Guinea Pig l -Asparaginase Type III

Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues

Structural basis for L27 domain-mediated assembly of signaling and cell polarity complexes

Structural basis for nucleotide-dependent regulation of membrane-associated guanylate kinase-like domains

Structural basis for substrate promiscuity of dCK

Structural basis for the dual thymidine and thymidylate kinase activity of herpes thymidine kinases

Structural characterization of new deoxycytidine kinase inhibitors rationalizes the affinity-determining moieties of the molecules

Structural characterization of the closed conformation of mouse guanylate kinase

Structural mechanism for substrate inhibition of the adenosine 5'-phosphosulfate kinase domain of human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 and its ramifications for enzyme regulation

Structure and Mutagenesis of Neural Cell Adhesion Molecule Domains: EVIDENCE FOR FLEXIBILITY IN THE PLACEMENT OF POLYSIALIC ACID ATTACHMENT SITES

Structure of human dCK suggests strategies to improve anticancer and antiviral therapy

Structures of Apo and Product-Bound Human l -Asparaginase: Insights into the Mechanism of Autoproteolysis and Substrate Hydrolysis

Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds

The Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1

The sugar ring of the nucleoside is required for productive substrate positioning in the active site of human deoxycytidine kinase (dCK): implications for the development of dCK-activated acyclic guanine analogues