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List of works by David Komander

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Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne

scientific article
LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-κB.

scientific article published on 8 May 2017
Lining the pockets of kinases and phosphatases.

scientific article published on 2 November 2006
The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases

scientific article published on 13 July 2016
Non-hydrolyzable Diubiquitin Probes Reveal Linkage-Specific Reactivity of Deubiquitylating Enzymes Mediated by S2 Pockets

scientific article
SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling

scientific article
Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure

scientific article
Recruitment of TBK1 to cytosol-invading Salmonella induces WIPI2-dependent antibacterial autophagy

scientific article published on July 2016
Emerging roles for Lys11-linked polyubiquitin in cellular regulation.

scientific article published on 07 June 2011
Cezanne (OTUD7B) regulates HIF-1α homeostasis in a proteasome-independent manner.

scientific article
Mechanism and regulation of the Lys6-selective deubiquitinase USP30.

scientific article
Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling

scientific article published on 20 September 2017
Cezanne regulates E2F1-dependent HIF2α expression

scientific article
Efficient APC/C substrate degradation in cells undergoing mitotic exit depends on K11 ubiquitin linkages

scientific article
Interactions of LY333531 and other bisindolyl maleimide inhibitors with PDK1

scientific article
A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes

scientific article
Role of T-loop phosphorylation in PDK1 activation, stability, and substrate binding

scientific article published on March 2005
Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2.

scientific article published in February 2018
Regulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULIN

scientific article
Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies

scientific article published on 20 February 2018
Structure of PINK1 in complex with its substrate ubiquitin.

scientific article published on 30 October 2017
Development of Diubiquitin-Based FRET Probes To Quantify Ubiquitin Linkage Specificity of Deubiquitinating Enzymes

scientific article published on 21 March 2016
OTULIN deficiency in ORAS causes cell type-specific LUBAC degradation, dysregulated TNF signalling and cell death

scientific article published on 01 March 2019
Novel inositol phospholipid headgroup surrogate crystallized in the pleckstrin homology domain of protein kinase Balpha

scientific article
A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN.

scientific article published on 28 August 2017
An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1.

scientific article published on 13 November 2017
Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins

scientific article published on 27 August 2018
Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease.

scientific article published on 08 August 2016
Insights into ubiquitin chain architecture using Ub-clipping

scientific article published on 15 August 2019
An essential role for the ATG8 ortholog LC3C in antibacterial autophagy

scientific article published on 22 February 2013
Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2

scientific article published on 26 August 2020
The Salmonella Effector SpvD Is a Cysteine Hydrolase with a Serovar-specific Polymorphism Influencing Catalytic Activity, Suppression of Immune Responses, and Bacterial Virulence

scientific article published on 27 October 2016
Synthesis and Analysis of K11-Linked Ubiquitin Chains

scientific article published on 01 January 2012
Enzymatic Assembly of Ubiquitin Chains

scientific article published on 01 January 2018
A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation

scholarly article by Jonathan N Pruneda et al published 5 November 2018 in Nature Microbiology
The tumour suppressor CYLD regulates the p53 DNA damage response

scientific article
Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity

The JAMM in the proteasome

scientific article published on 01 April 2014
Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling

scientific article published on 01 March 2020
Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential

scientific article published in April 2018
Regulation of the endosomal SNX27-retromer by OTULIN

scientific article published on 20 September 2019
OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer

scientific article published on 30 March 2020
Erratum: Mechanism of phospho-ubiquitin-induced PARKIN activation

scientific article published on 23 September 2015
A further case of Dop‐ing in bacterial pupylation

scientific article published on September 17, 2010
Synthesis of Poly-Ubiquitin Chains Using a Bifunctional Ubiquitin Monomer.

scientific article published on 27 November 2017
CYLD Tidies Up Dishevelled Signaling

scientific article published on March 12, 2010
USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation

scientific article published on 07 July 2020
Identification and characterization of diverse OTU deubiquitinases in bacteria

scientific article published on 22 June 2020
Purification, crystallization and preliminary X-ray diffraction of a proteolytic fragment of PDK1 containing the pleckstrin homology domain.

scientific article published on 23 January 2004
Publisher Correction: Breaking the chains: deubiquitylating enzyme specificity begets function

scientific article published on 01 May 2019

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