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List of works by Eric Boerwinkle

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article

<i>NAT8</i> Variants, N-Acetylated Amino Acids, and Progression of CKD

scientific article published on 30 December 2020

A Causal Network Analysis of the Fatty Acid Metabolome in African-Americans Reveals a Critical Role for Palmitoleate and Margarate

scientific article published on August 2016

A Fast Implementation of a Scan Statistic for Identifying Chromosomal Patterns of Genome Wide Association Studies

scientific article

A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration

scientific article published on 5 July 2016

A Genocentric Approach to Discovery of Mendelian Disorders

scientific article published on 24 October 2019

A Genome-wide Association Study Discovers 46 Loci of the Human Metabolome in the Hispanic Community Health Study/Study of Latinos

scientific article published on 01 October 2020

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A Mendelian randomization of γ' and total fibrinogen levels on venous thromboembolism and ischemic stroke

scientific article published on 28 July 2020

A biallelic ANTXR1 variant expands the anthrax toxin receptor associated phenotype to tooth agenesis

scientific article published on 13 February 2018

A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressure

scientific article published on 23 May 2020

A bioinformatics pipeline for estimating mitochondrial DNA copy number and heteroplasmy levels from whole genome sequencing data

scientific article published on 17 May 2022

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

scientific journal article

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A causal network analysis in an observational study identifies metabolomics pathways influencing plasma triglyceride levels

scientific article published on 11 May 2016

A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping. I. Basic theory and an analysis of alcohol dehydrogenase activity in Drosophila

scientific article

A common allele on chromosome 9 associated with coronary heart disease

scientific article

A comparison of serum creatinine-based methods for identifying chronic kidney disease in hypertensive individuals and their siblings

scientific article published in June 2006

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

scientific article

A diagnostic ceiling for exome sequencing in cerebellar ataxia and related neurological disorders

scientific article published on 06 November 2019

A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases

scientific journal article

A framework for the interpretation of de novo mutation in human disease

scientific article (publication date: 3 August 2014)

A generalized weighted quantile sum approach for analyzing correlated data in the presence of interactions

scientific article published on 06 May 2019

A genetic association study of activated partial thromboplastin time in European Americans and African Americans: the ARIC Study

scientific article

A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies

scientific article published on 12 June 2012

A genetic variant on chromosome 9p21 and incident heart failure in the ARIC study

scientific article published on 26 March 2009

A genome scan for loci influencing levels and trends of lipoprotein lipid-related traits since childhood: The Bogalusa Heart Study

scientific article

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium

scientific article published on 05 May 2013

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease

scientific article

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology

scientific article published on 14 January 2019

A genome-wide association study of aging

scientific article

A genome-wide linkage scan for ankle-brachial index in African American and non-Hispanic white subjects participating in the GENOA study

scientific article published on 8 November 2005

A genome-wide linkage scan for diabetic retinopathy susceptibility genes in Mexican Americans with type 2 diabetes from Starr County, Texas

scientific article published on 24 January 2007

A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.

scientific article

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

scientific article published on June 2016

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

scientific article

A hybrid computational strategy to address WGS variant analysis in >5000 samples

scientific article published on 10 September 2016

A meta-analysis of genome-wide linkage scans for hypertension: the National Heart, Lung and Blood Institute Family Blood Pressure Program

scientific article published on 01 February 2003

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A multilocus approach to the antihypertensive pharmacogenetics of hydrochlorothiazide

scientific article published on 01 May 2005

A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease

scientific article published on 23 October 2007

A novel measure of genetic distance for highly polymorphic tandem repeat loci

scientific article published in September 1995

A novel quantitative trait locus on chromosome 1 with pleiotropic effects on HDL-cholesterol and LDL particle size in hypertensive sibships

scientific article published in August 2005

A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains

scientific article

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A prospective study of serum metabolites and risk of ischemic stroke

scientific article published on 13 March 2019

A scan statistic for identifying chromosomal patterns of SNP association

scientific article published in November 2006

A statistical analysis of spot variation using the two-dimensional polyacrylamide gel electrophoresis

scientific article published in February 1986

A three codon insertion/deletion polymorphism in the signal peptide region of the human apolipoprotein B (APOB) gene directly typed by the polymerase chain reaction

scientific article

A unique length polymorphism in the signal peptide region of the apolipoprotein B gene in Mexican-Americans

scientific article published in December 1990

A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels

scientific article

A whole-genome scan for stroke or myocardial infarction in family blood pressure program families

scientific article

ACAT: A Fast and Powerful p Value Combination Method for Rare-Variant Analysis in Sequencing Studies

scientific article published on 01 March 2019

ADD1 460W Allele Associated With Cardiovascular Disease in Hypertensive Individuals

scientific article published on 01 June 2002

ANGPTL3 Deficiency and Protection Against Coronary Artery Disease

scientific article published on 29 March 2017

APOA5polymorphisms influence plasma triglycerides in young, healthy African Americans and whites of the CARDIA Study

scientific article published on 16 December 2004

APOE modulates the correlation between triglycerides, cholesterol, and CHD through pleiotropy, and gene-by-gene interactions

scientific article published on 04 October 2013

APOE/C1/C4/C2 hepatic control region polymorphism influences plasma apoE and LDL cholesterol levels

scientific article

APOL1 Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis

scientific article published on 05 August 2019

APOL1 variants associate with increased risk of CKD among African Americans

scientific article published on 13 June 2013

Absence of an interaction between the angiotensin-converting enzyme insertion-deletion polymorphism and pravastatin on cardiovascular disease in high-risk hypertensive patients: the Genetics of Hypertension-Associated Treatment (GenHAT) study

scientific article published on January 2007

Abstract 14629: Rare Variants for Electrocardiographic Traits Identify Arrhythmia Susceptibility Genes

scientific article published in 2020

Admixture mapping of obesity-related traits in African Americans: the Atherosclerosis Risk in Communities (ARIC) Study

scientific article

Admixture mapping of quantitative trait loci for blood lipids in African-Americans

scientific article published on 20 March 2009

Admixture mapping scans identify a locus affecting retinal vascular caliber in hypertensive African Americans: the Atherosclerosis Risk in Communities (ARIC) study

scientific article

African ancestry and its correlation to type 2 diabetes in African Americans: a genetic admixture analysis in three U.S. population cohorts

scientific article

Ala54Thr polymorphism of the fatty acid binding protein 2 gene and saturated fat intake in relation to lipid levels and insulin resistance: the Coronary Artery Risk Development in Young Adults (CARDIA) study

scientific article published on 18 June 2009

Allele frequency distribution of the (TG)n(AG)m microsatellite in the apolipoprotein C-II gene

article

Alternative genomic diagnoses for individuals with a clinical diagnosis of Dubowitz syndrome

scientific article published on 24 October 2020

An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group

scientific article published on 27 May 2016

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

scientific article published on 31 May 2017

An NPPB Promoter Polymorphism Associated With Elevated N-Terminal pro-B-Type Natriuretic Peptide and Lower Blood Pressure, Hypertension, and Mortality

scientific article published on 24 March 2017

An assessment of incremental coronary risk prediction using C-reactive protein and other novel risk markers: the atherosclerosis risk in communities study

scientific article published on 01 July 2006

An empirical comparison of meta-analysis and mega-analysis of individual participant data for identifying gene-environment interactions

scientific article

An enhancer polymorphism at the cardiomyocyte intercalated disc protein NOS1AP locus is a major regulator of the QT interval

scientific article

An entropy-based genome-wide transmission/disequilibrium test

scientific article published on 13 February 2007

An entropy-based statistic for genomewide association studies

scientific article

An exome array study of the plasma metabolome

scientific article published on 25 July 2016

An insertion deletion polymorphism in the signal peptide of the human apolipoprotein B gene

article

An investigation of genome-wide associations of hypertension with microsatellite markers in the family blood pressure program (FBPP)

scientific article published on 20 March 2007

An updated meta-analysis of genome scans for hypertension and blood pressure in the NHLBI Family Blood Pressure Program (FBPP)

scientific article published on 01 January 2006

Analysis commons, a team approach to discovery in a big-data environment for genetic epidemiology

scientific article published in October 2017

Analysis of Sequence Data Under Multivariate Trait-Dependent Sampling

scientific article

Analysis of loss-of-function variants and 20 risk factor phenotypes in 8,554 individuals identifies loci influencing chronic disease

scientific article published on 27 April 2015

Analysis of putative cis-regulatory elements regulating blood pressure variation

scientific article published on 21 May 2020

Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls

scientific article

Analysis of the distribution of erythrocyte sodium lithium countertransport in a sample representative of the general population

scientific article published on January 1986

Antihypertensive pharmacogenetic effect of fibrinogen-beta variant -455G>A on cardiovascular disease, end-stage renal disease, and mortality: the GenHAT study

scientific article published on June 2009

Antihypertensive pharmacogenetics: getting the right drug into the right patient

scientific article

Apolipoprotein E and progression of chronic kidney disease

scientific article

Apolipoprotein E genotype and gallbladder disease risk in a large population-based cohort

scientific article published in August 2006

Apolipoprotein E genotype and incident ischemic stroke: the Atherosclerosis Risk in Communities Study

scientific article published on 06 October 2005

Apolipoprotein E polymorphism influences postprandial retinyl palmitate but not triglyceride concentrations

scientific article published in February 1994

Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants

scientific article published on 07 June 2006

Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism

scientific article

Application of machine learning algorithms to predict coronary artery calcification with a sibship-based design

scientific article

Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?

scientific article published on 02 July 2013

Assessing structural variation in a personal genome-towards a human reference diploid genome.

scientific article published on 11 April 2015

Association Between Midlife Obesity and Kidney Function Trajectories: The Atherosclerosis Risk in Communities (ARIC) Study

scientific article published on 23 September 2020

Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)

Association and linkage analysis of the alpha-adducin gene and blood pressure

scientific article published on June 2000

Association between Mitochondrial DNA Copy Number in Peripheral Blood and Incident CKD in the Atherosclerosis Risk in Communities Study

scientific article published on 21 January 2016

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

scientific article

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

scientific article published on 23 December 2011

Association between high-sensitivity troponin T and cardiovascular risk in individuals with and without metabolic syndrome: The ARIC study

scientific article published on 9 December 2016

Association between mitochondrial DNA copy number and sudden cardiac death: findings from the Atherosclerosis Risk in Communities study (ARIC).

scientific article published on 30 June 2017

Association between patterns of nucleotide variation across the three fibrinogen genes and plasma fibrinogen levels: the Coronary Artery Risk Development in Young Adults (CARDIA) study

scientific article published in June 2006

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

scientific article

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

scientific article published on 21 March 2019

Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study

scientific article published on 15 July 2016

Association of KCNJ1 variation with change in fasting glucose and new onset diabetes during HCTZ treatment ⬇️

scientific article published on August 21, 2012

Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism.

scientific article

Association of Mitochondrial DNA Copy Number With Cardiovascular Disease

scientific article published on 11 October 2017

Association of NOS3 Glu298Asp SNP with hypertension and possible effect modification of dietary fat intake in the ARIC study

scientific article

Association of Rare Loss-Of-Function Alleles in HAL, Serum Histidine: Levels and Incident Coronary Heart Disease

scientific article published on 8 January 2015

Association of SERPINA9 gene variants with carotid artery atherosclerosis: the Atherosclerosis Risk in Communities (ARIC) Carotid MRI Study

scientific article

Association of Sickle Cell Trait with Measures of Cognitive Function and Dementia in African Americans

scientific article published in 2018

Association of Variants with Blood Pressure in the Atherosclerosis Risk in Communities Study

Association of a fasting glucose genetic risk score with subclinical atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) study ⬇️

scientific article

Association of chromosome 12 locus with antihypertensive response to hydrochlorothiazide may involve differential YEATS4 expression ⬇️

scientific article published on February 21, 2012

Association of circulating matrix metalloproteinases with carotid artery characteristics: the Atherosclerosis Risk in Communities Carotid MRI Study

scientific article

Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing

scientific article published on 31 May 2012

Association of genetic variants and incident coronary heart disease in multiethnic cohorts: the PAGE study

scientific article published on 31 October 2011

Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies

scientific article published on 16 December 2012

Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium

scientific journal article

Association of glycemic index and glycemic load with risk of incident coronary heart disease among Whites and African Americans with and without type 2 diabetes: the Atherosclerosis Risk in Communities study

scientific article

Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

scientific article (publication date: June 2014)

Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks

scientific article

Association of mitochondrial DNA levels with frailty and all-cause mortality

scientific article

Association of monocyte myeloperoxidase with incident cardiovascular disease: The Atherosclerosis Risk in Communities Study

scientific article published in PLoS ONE

Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts

scientific article published on April 2009

Association of polymorphisms in NOS3 with the ankle-brachial index in hypertensive adults

scientific article

Association of rs780094 in GCKR with metabolic traits and incident diabetes and cardiovascular disease: the ARIC Study

scientific article

Association of sickle cell trait with chronic kidney disease and albuminuria in African Americans

scientific article

Association of sickle cell trait with measures of cognitive function and dementia in African Americans

scholarly article by Nemin Chen et al published 22 July 2019 in eNeurologicalSci

Association of the IGF1 gene with fasting insulin levels

scientific article published on 10 February 2016

Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status: The ARIC study

scientific article published on 21 February 2008

Association of the platelet GPIIb/IIIa polymorphism with atherosclerotic plaque morphology: the Atherosclerosis Risk in Communities (ARIC) Study

scientific article

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

scientific article

Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects

Association of variants in NEDD4L with blood pressure response and adverse cardiovascular outcomes in hypertensive patients treated with thiazide diuretics

scientific article published on April 2013

Association studies for next-generation sequencing

scientific article

Associations Between Carotid Artery Plaque Burden, Plaque Characteristics, and Cardiovascular Events: The ARIC Carotid Magnetic Resonance Imaging Study

scientific article published on 18 November 2020

Associations Between the Serum Metabolome and All-Cause Mortality Among African Americans in the Atherosclerosis Risk in Communities (ARIC) Study

scientific article published on 7 March 2016

Associations between HDL-cholesterol and polymorphisms in hepatic lipase and lipoprotein lipase genes are modified by dietary fat intake in African American and White adults

scientific article published on 8 December 2006

Associations between SLC16A11 variants and diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

scientific article published in Scientific Reports

Associations between dietary patterns and flow cytometry-measured biomarkers of inflammation and cellular activation in the Atherosclerosis Risk in Communities (ARIC) Carotid Artery MRI Study

scientific article

Associations between lipoprotein(a) levels and cardiovascular outcomes in black and white subjects: the Atherosclerosis Risk in Communities (ARIC) Study

scientific article

Associations between metabolomic compounds and incident heart failure among African Americans: the ARIC Study

scientific article published on 20 June 2013

Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium

scientific article

Associations of allelic differences at the A-I/C-III/A-IV gene cluster with carotid artery intima-media thickness and plasma lipid transport in hypercholesterolemic-hypertriglyceridemic humans

scientific article published on 01 June 1994

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Associations of lipoprotein lipase gene polymorphisms with longitudinal plasma lipid trends in young adults: The Coronary Artery Risk Development in Young Adults (CARDIA) study

scientific article

Atherosclerosis Risk in Communities (ARIC) Carotid MRI flow cytometry study of monocyte and platelet markers: intraindividual variability and reliability

scientific article published on 29 May 2008

Atlas-CNV: a validated approach to call single-exon CNVs in the eMERGESeq gene panel

scientific article published on 20 March 2019

Atypical angiopoietin-like protein that regulates ANGPTL3 ⬇️

scientific article published on November 12, 2012

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 01 May 2019

Autosomal genome scan for loci linked to blood pressure levels and trends since childhood: the Bogalusa Heart Study

scientific article

Autosomal genome-wide scan for coronary artery calcification loci in sibships at high risk for hypertension

scientific article published in March 2002

Baseline predictors of central aortic blood pressure: a PEAR substudy

scientific article published on 03 January 2014

Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium

scientific article

Beta 2 adrenergic receptor 5' haplotypes influence promoter activity

scientific article

Beta(2)-adrenergic receptor polymorphism and nitric oxide-dependent forearm blood flow responses to isoproterenol in humans

scientific article published in January 2003

Beta-adrenergic receptor genes are associated with arterial stiffness in black and white adults: the Bogalusa Heart Study

scientific article published in December 2007

Beta-fibrinogen gene -455G/A polymorphism and coronary heart disease incidence: the Atherosclerosis Risk in Communities (ARIC) Study

scientific article published in April 2001

Beta3-adrenergic receptor Trp64Arg polymorphism does not predict incident CHD or carotid intima-media thickness in a community-based sample of whites: the ARIC study. Atherosclerosis Risk in Communities

scientific article

Biallelic GRM7 variants cause epilepsy, microcephaly, and cerebral atrophy

scientific article published on 14 April 2020

Bias of the contribution of single-locus effects to the variance of a quantitative trait

scientific article

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Biomarkers and degree of atherosclerosis are independently associated with incident atherosclerotic cardiovascular disease in a primary prevention cohort: The ARIC study

scientific article published on 25 August 2016

Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease

scientific article published on 19 August 2019

Blood Pressure Responses and Metabolic Effects of Hydrochlorothiazide and Atenolol ⬇️

scientific article published on November 17, 2011

Blood lead concentrations in Jamaican children with and without autism spectrum disorder

scientific article

Blood manganese concentrations in Jamaican children with and without autism spectrum disorders

scientific article

Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies.

scientific article

Body mass index modulates blood pressure heritability: the Family Blood Pressure Program

scientific article published on 12 September 2013

C-reactive Protein among Community-Dwelling Hypertensives on Single-agent Antihypertensive Treatment

scientific article published on July 2009

C825T polymorphism of the G protein beta(3)-subunit and antihypertensive response to a thiazide diuretic

scientific article

CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis

scientific article published on 19 February 2018

COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis

scientific article published on 20 April 2015

Carbohydrate intake modifies associations between ANGPTL4[E40K] genotype and HDL-cholesterol concentrations in White men from the Atherosclerosis Risk in Communities (ARIC) study

scientific article published on 02 July 2008

Cardiac Structure and Function Across the Spectrum of Aldosteronism: the Atherosclerosis Risk in Communities Study

scientific article published in 2022

Cardiac troponin T measured by a highly sensitive assay predicts coronary heart disease, heart failure, and mortality in the Atherosclerosis Risk in Communities Study

scientific article

Cardiovascular biomarkers and subclinical brain disease in the atherosclerosis risk in communities study.

scientific article

Carotid arterial wall characteristics are associated with incident ischemic stroke but not coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) study

scientific article published on 27 October 2011

Carotid intima-media thickness and presence or absence of plaque improves prediction of coronary heart disease risk: the ARIC (Atherosclerosis Risk In Communities) study

scientific article

Causal Role of Alcohol Consumption in an Improved Lipid Profile: The Atherosclerosis Risk in Communities (ARIC) Study

scientific article published on 5 February 2016

Centers for Mendelian Genomics: A decade of facilitating gene discovery

scientific article published on 09 February 2022

Cerebral small vessel disease genomics and its implications across the lifespan

scientific article published on 08 December 2020

Cerebral white matter hyperintensities on MRI and acceleration of epigenetic aging: the atherosclerosis risk in communities study

scientific article published on 14 February 2017

Ceruloplasmin and heart failure in the Atherosclerosis Risk in Communities study

scientific article published on 16 July 2013

Chromosome 9p21 single nucleotide polymorphisms are not associated with recurrent myocardial infarction in patients with established coronary artery disease

scientific article published on 09 February 2012

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

scientific article

Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) study

scientific article

Cladistic structure within the human Lipoprotein lipase gene and its implications for phenotypic association studies.

scientific article

Clan genomics and the complex architecture of human disease

scientific article published on September 2011

Clinical implications of JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a U.S. population insights from the ARIC (Atherosclerosis Risk in Communities) study

scientific article

Cohort Profile: The Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment Protocol (RIGHT Protocol)

scientific article published on 01 February 2020

Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts

scientific article (publication date: February 2009)

Combined analysis of genomewide scans for adult height: results from the NHLBI Family Blood Pressure Program

scientific article published on March 2003

Combined effects of endothelial nitric oxide synthase gene polymorphism (G894T) and insulin resistance status on blood pressure and familial risk of hypertension in young adults: the Bogalusa Heart Study

scientific article

Combined genealogical, mapping, and expression approaches to identify spontaneously hypertensive rat hypertension candidate genes

scientific article published on 14 February 2005

Common Coding Variants in Are Associated With the Nav1.8 Late Current and Cardiac Conduction

scientific article published on 01 May 2018

Common INSIG2 polymorphisms are associated with age-related changes in body size and high-density lipoprotein cholesterol from young adulthood to middle age.

scientific article

Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project

scientific article

Common carotid artery intima-media thickness is as good as carotid intima-media thickness of all carotid artery segments in improving prediction of coronary heart disease risk in the Atherosclerosis Risk in Communities (ARIC) study

scientific article

Common genetic variants associate with serum phosphorus concentration

scientific article

Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

scientific article

Common variants at ten loci modulate the QT interval duration in the QTSCD Study

scientific article

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

scientific article

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

scientific article published on 7 June 2021

Common variants in KCNN3 are associated with lone atrial fibrillation

scientific article

Common variants in Mendelian kidney disease genes and their association with renal function

scientific article published on 12 September 2013

Common variants in the GDF5-UQCC region are associated with variation in human height

scientific article

Comparison and integration of deleteriousness prediction methods for nonsynonymous SNVs in whole exome sequencing studies

scientific article

Comparison of office, ambulatory, and home blood pressure antihypertensive response to atenolol and hydrochlorthiazide

scientific article

Comparison of strategies for selecting single nucleotide polymorphisms for case/control association studies

scientific article published on 17 June 2003

Comprehensive evaluation of apolipoprotein H gene (APOH) variation identifies novel associations with measures of lipid metabolism in GENOA.

scientific article published on August 2008

Comprehensive evaluation of imputation performance in African Americans

scientific article

Comprehensive genomic analysis of patients with disorders of cerebral cortical development

scientific article published on 30 April 2018

Concentration of lead, mercury, cadmium, aluminum, arsenic and manganese in umbilical cord blood of Jamaican newborns

scientific article published on 23 April 2015

Concentrations of Polychlorinated Biphenyls and Organochlorine Pesticides in Umbilical Cord Blood Serum of Newborns in Kingston, Jamaica.

scientific article published on 21 October 2016

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

scientific article

Consistent effects of genes involved in reverse cholesterol transport on plasma lipid and apolipoprotein levels in CARDIA participants

scientific article (publication date: August 2006)

Context-dependent associations of the ACE I/D polymorphism with blood pressure

scientific article published on 01 October 1999

Contrasting multi-site genotypic distributions among discordant quantitative phenotypes: theAPOA1/C3/A4/A5 gene cluster and cardiovascular disease risk factors

article

Contribution of regulatory and structural variations in APOE to predicting dyslipidemia

scientific article

Contributions of 18 additional DNA sequence variations in the gene encoding apolipoprotein E to explaining variation in quantitative measures of lipid metabolism

scientific article published on 5 August 2002

Contributions of rare coding variants in hypotension syndrome genes to population blood pressure variation

article

Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrations

scientific article

Coronary heart disease and genetic variants with low phospholipase A2 activity

scientific article

Coronary heart disease risk, aspirin use, and apolipoprotein(a) 4399Met allele in the Atherosclerosis Risk in Communities (ARIC) study

scientific article published in July 2009

Correction: African Ancestry and Its Correlation to Type 2 Diabetes in African Americans: A Genetic Admixture Analysis in Three U.S. Population Cohorts.

scientific article published on 20 September 2012

Correction: Four Novel Loci (19q13, 6q24, 12q24, and 5q14) Influence the Microcirculation In Vivo.

scientific article

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: Identification, Replication, and Fine-Mapping of Loci Associated with Adult Height in Individuals of African Ancestry.

scientific article published on 21 November 2011

Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

scientific article

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

scientific article published on 21 October 2019

Correlates of carotid plaque presence and composition as measured by MRI: the Atherosclerosis Risk in Communities Study

scientific article published on 11 May 2009

Corrigendum to 'Association of sickle cell trait with measures of cognitive function and dementia in African Americans' <i>eNeurologicalSci,</i> Vol. 16 (2019), 100,201

scientific article published on 12 October 2020

Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article published on 26 May 2017

Corrigendum: Rare coding variants and X-linked loci associated with age at menarche

scientific article published on 17 December 2015

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

Corticotropin releasing hormone (CRH) gene variation: comprehensive resequencing for variant and molecular haplotype discovery in monosomic hybrid cell lines

scientific article published on December 2007

Creating a data resource: what will it take to build a medical information commons?

scientific article published on 22 September 2017

DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation

scientific article published on 30 November 2017

DNA methylation age is associated with an altered hemostatic profile in a multi-ethnic meta-analysis

article

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

scientific article published on 12 December 2016

DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene

scientific article published in July 1998

De novo truncating mutations in AHDC1 in individuals with syndromic expressive language delay, hypotonia, and sleep apnea

scientific article

Deep resequencing reveals excess rare recent variants consistent with explosive population growth

scientific article published on 30 November 2010

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Demographic, environmental, and genetic predictors of metabolic side effects of hydrochlorothiazide treatment in hypertensive subjects

scientific article published in August 2005

Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls

scientific article

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

scientific article

Determinants of the success of whole-genome association testing

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Diabetes genes and prostate cancer in the Atherosclerosis Risk in Communities study

scientific article

Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia

scientific article

Diagnostic tools in linkage analysis for quantitative traits

scientific article published in May 2003

Dietary intake and gene variation influence the response of plasma lipids to dietary intervention

scientific article published in January 1992

Direct Estimates of the Genomic Contributions to Blood Pressure Heritability within a Population-Based Cohort (ARIC).

scientific article published on 10 July 2015

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Discovery and fine mapping of serum protein loci through transethnic meta-analysis

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure

scientific article

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

Dissociation betweenAPOC3variants, hepatic triglyceride content and insulin resistance ⬇️

scientific article published on December 10, 2010

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

scientific article

Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium

scientific article

Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval

scientific article published on 05 March 2013

Dynamic Scan Procedure for Detecting Rare-Variant Association Regions in Whole-Genome Sequencing Studies

scientific article published on 12 April 2019

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

scientific article published on 24 August 2020

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

ESR1 polymorphism is associated with plasma lipid and apolipoprotein levels in Caucasians of the Rochester Family Heart Study

scientific article published on 30 April 2008

Effect of 9p21 genetic variation on coronary heart disease is not modified by other risk markers. The Atherosclerosis Risk in Communities (ARIC) Study

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Effect of Apolipoprotein E Polymorphism on Fasting Retinyl Palmitate Level ⬇️

scientific article published on August 1, 1995

Effect of plasma MicroRNA on antihypertensive response to beta blockers in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) studies

scientific article published on 10 February 2019

Effects of Gender-Specific Differences, Inflammatory Response, and Genetic Variation on the Associations Among Depressive Symptoms and the Risk of Major Adverse Coronary Events in Patients With Acute Coronary Syndrome

scientific article published in January 2018

Effects of apolipoprotein E genotype on blood cholesterol in adolescent girls

scientific article

Effects of endothelial nitric oxide synthase, α-adducin, and other candidate gene polymorphisms on blood pressure response to hydrochlorothiazide ⬇️

scientific article published on 01 October 2003

Effects of genetic variation in H3K79 methylation regulatory genes on clinical blood pressure and blood pressure response to hydrochlorothiazide ⬇️

scientific article published on March 22, 2012

Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations

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Effects of rare and common blood pressure gene variants on essential hypertension: results from the Family Blood Pressure Program, CLUE, and Atherosclerosis Risk in Communities studies

scientific article published on 12 November 2012

Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies

scientific article published on 10 January 2019

Efficient gene-environment interaction tests for large biobank-scale sequencing studies

scientific article published on 30 August 2020

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies

scientific article published on 14 October 2011

Epidemiology of atrial fibrillation in the All of Us Research Program

scientific article published on 16 March 2022

Epigenetic Age Acceleration and Cognitive Function in African American Adults in Midlife: The Atherosclerosis Risk in Communities Study

scientific article published on 01 February 2020

Epigenome-wide association studies identify DNA methylation associated with kidney function

scientific article published on 3 November 2017

Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci

scientific article published in May 2015

Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference

scientific article published on July 2015

Epistasis analysis for quantitative traits by functional regression model

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Epistatic effects between two genes in the renin-angiotensin system and systolic blood pressure and coronary artery calcification.

scientific article published on 28 March 2006

Erratum to ‘Glutathione S-transferase genotype as a susceptibility factor in smoking-related coronary heart disease’

scholarly article published in Atherosclerosis

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

scientific article published in July 2017

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Essential hypertension vs. secondary hypertension among children

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Estimating population genetic parameters and comparing model goodness-of-fit using DNA sequences with error

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Ethnic and sex differences in the prevalence, treatment, and control of dyslipidemia among hypertensive adults in the GENOA study

scientific article

Ethnic differences in peripheral arterial disease in the NHLBI Genetic Epidemiology Network of Arteriopathy (GENOA) study

scientific article published on 01 November 2003

Ethnicity and human genetic linkage maps

scientific article

Evaluating the Context-Dependent Effect of Family History of Stroke in a Genome Scan for Hypertension

scientific article published on 24 April 2003

Evaluation of microarray-based DNA methylation measurement using technical replicates: the Atherosclerosis Risk In Communities (ARIC) Study

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Evaluation of mitochondrial DNA copy number estimation techniques

scientific article published on 31 January 2020

Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study

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Evidence for a gene influencing heart rate on chromosome 5p13-14 in a meta-analysis of genome-wide scans from the NHLBI Family Blood Pressure Program

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Evidence for consistent intragenic and intergenic interactions between SNP effects in the APOA1/C3/A4/A5 gene cluster

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Evidence for non-additive influence of single nucleotide polymorphisms within the apolipoprotein E gene.

scientific article

Evolution and functional impact of rare coding variation from deep sequencing of human exomes

scientific article (publication date: 6 July 2012)

Exome Chip Analysis Identifies Low-Frequency a on Brain Magnetic Imaging

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

scientific article

Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy

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Exome sequencing in mostly consanguineous Arab families with neurologic disease provides a high potential molecular diagnosis rate

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Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

article by Jason Flannick et al published 22 May 2019 in Nature

Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017

Exon sequencing of PAX3 and T (brachyury) in cases with spina bifida.

scientific article published on 02 August 2013

FBN1 contributing to familial congenital diaphragmatic hernia.

scientific article published on 3 March 2015

FLAGS: A Flexible and Adaptive Association Test for Gene Sets Using Summary Statistics.

scientific article published on 15 January 2016

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

Factor XIIIA Val34Leu polymorphism does not predict risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) Study

scientific article published on 01 February 2002

Factors associated with blood lead concentrations of children in Jamaica

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Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD

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Familial aggregation of hypertension treatment and control in the Genetic Epidemiology Network of Arteriopathy (GENOA) study

scientific article published on 01 May 2004

Family-based association study of matrix metalloproteinase-3 and -9 haplotypes with susceptibility to ischemic white matter injury

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Fat mass and obesity gene and cognitive decline: the Atherosclerosis Risk in Communities Study

scientific article published on 7 November 2012

Feature (gene) selection in gene expression-based tumor classification

scientific article published on July 2001

Field of needs: the genetics of stroke.

scientific article

Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms

scientific article published on 22 May 2017

Fine Mapping and Identification of BMI Loci in African Americans

scientific article published on October 2013

Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

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Five blood pressure loci identified by an updated genome-wide linkage scan: meta-analysis of the Family Blood Pressure Program

scientific article

Five common gene variants identify elevated genetic risk for coronary heart disease

scientific article

Following-up genome-wide association study signals: lessons learned from Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

scientific article

Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo

scientific article published in October 2010

Frequency and effects of apolipoprotein E polymorphism in Mexican-American NIDDM subjects

scientific article published in March 1991

Frequency and effects of the apolipoprotein A-IV polymorphism

scientific article published on 01 June 1990

From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I.

scientific article published on October 2003

From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II.

scientific article published on October 2003

Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample

scientific article published on 01 April 2019

G protein receptor kinase 4 polymorphisms: β-blocker pharmacogenetics and treatment-related outcomes in hypertension

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G-6A polymorphism of angiotensinogen gene modulates the effect of blood pressure on carotid intima-media thickness. The Bogalusa Heart Study

scientific article published in October 2007

G-6A polymorphism of the angiotensinogen gene and its association with left ventricular mass in asymptomatic young adults from a biethnic community: the Bogalusa Heart Study

scientific article published in November 2005

G-protein beta3 subunit and alpha-adducin polymorphisms and risk of subclinical and clinical stroke

scientific article published in April 2001

GOSR2 Lys67Arg is associated with hypertension in whites

scientific article

GSTM1 Deletion Exaggerates Kidney Injury in Experimental Mouse Models and Confers the Protective Effect of Cruciferous Vegetables in Mice and Humans

scientific article published on 14 November 2019

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

scientific article published in Nature Communications

Gender- and age-dependent relationships between the E-selectin S128R polymorphism and coronary artery calcification

scientific article published in July 2001

Gender-specific influence of NO synthase gene on blood pressure since childhood: the Bogalusa Heart Study

scientific article

Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans

scientific article published on March 2009

Gene expression profiling and functional proteomic analysis reveal perturbed kinase-mediated signaling in genetic stroke susceptibility

scientific article published on 29 September 2003

Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment ⬇️

scientific article published on May 1, 2012

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia

scientific article

Gene-by-Psychosocial Factor Interactions Influence Diastolic Blood Pressure in European and African Ancestry Populations: Meta-Analysis of Four Cohort Studies

scientific article

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

scientific article published on 20 February 2014

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

scientific article published on 05 May 2020

Gene-environment interplay in common complex diseases: forging an integrative model—recommendations from an NIH workshop

scientific article

Gene-specific function prediction for non-synonymous mutations in monogenic diabetes genes

scientific article

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

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Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations

scientific article published on 21 November 2016

Generalized T2 test for genome association studies

scientific article published on 29 March 2002

Generating a robust statistical causal structure over 13 cardiovascular disease risk factors using genomics data

scientific article published on 28 January 2016

Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease

scientific article published on November 2015

Genetic Burden Contributing to Extremely Low or High Bone Mineral Density in a Senior Male Population From the Osteoporotic Fractures in Men Study (MrOS)

scientific article published on 22 January 2020

Genetic Diversity Turns a New PAGE in Our Understanding of Complex Traits

Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

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Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials

scientific article published on 2 November 2017

Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients From the PEAR Study (Pharmacogenomic Evaluation of Antihypertensive Responses)

scientific article published on 01 April 2018

Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections

scientific article published on 25 August 2016

Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk

scientific article published on 01 October 2018

Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.

scientific article published on 27 February 2018

Genetic analyses of diverse populations improves discovery for complex traits

scientific article published on 19 June 2019

Genetic analysis of atherosclerosis: a research paradigm for the common chronic diseases

scientific article published on January 1996

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic architecture of inter-individual variability in apolipoprotein, lipoprotein and lipid phenotypes.

scientific article

Genetic architecture of laterality defects revealed by whole exome sequencing

scientific article published on 08 January 2019

Genetic architecture of lipid traits in the Hispanic community health study/study of Latinos

scientific article published on 12 October 2017

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

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Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease

scientific article

Genetic determinants influencing human serum metabolome among African Americans

scientific article

Genetic determinants of plasma von Willebrand factor antigen levels: a target gene SNP and haplotype analysis of ARIC cohort

scientific article

Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium

scientific article published on 2 February 2012

Genetic discoveries and nursing implications for complex disease prevention and management

scientific article published in July 2004

Genetic evidence of assortative mating in humans

article

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

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Genetic insights into biological mechanisms governing human ovarian ageing

scientific article

Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles

scientific article

Genetic linkage and imprinting effects on body mass index in children and young adults

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Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

scientific article published in 2022

Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies

scientific article published on 23 January 2016

Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

scientific article published on 13 November 2020

Genetic loci for retinal arteriolar microcirculation

scientific article

Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study

scientific article published on 29 May 2015

Genetic markers associated with plasma protein C level in African Americans: the atherosclerosis risk in communities (ARIC) study

scientific article

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic predisposition to higher blood pressure increases coronary artery disease risk

scientific article published on 11 March 2013

Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants associated with risk of Alzheimer's disease contribute to cognitive change in midlife: The Atherosclerosis Risk in Communities Study

scientific article published on 26 October 2016

Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes

scientific article

Genetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities study

scientific article

Genetic variants in TLR2 and TLR4 are associated with markers of monocyte activation: the Atherosclerosis Risk in Communities MRI Study

scientific article

Genetic variants in microRNA genes and targets associated with cardiovascular disease risk factors in the African-American population

scientific article published on 20 December 2017

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk

scientific article

Genetic variation associated with circulating monocyte count in the eMERGE Network

scientific article published on 12 January 2013

Genetic variation at the apolipoprotein gene loci contribute to response of plasma lipids to dietary change

scientific article published on 01 January 1990

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

scientific journal article

Genetic variation of glucose transporter-1 (GLUT1) and albuminuria in 10,278 European Americans and African Americans: a case-control study in the Atherosclerosis Risk in Communities (ARIC) study

scientific article

Genetic variation of the renin-angiotensin system and chronic kidney disease progression in black individuals in the atherosclerosis risk in communities study

scientific article published on 5 January 2006

Genetic variations associated with echocardiographic left ventricular traits in hypertensive blacks.

scientific article

Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations

scientific article published on 09 February 2009

Genetically hypertensive Brown Norway congenic rat strains suggest intermediate traits underlying genetic hypertension

scientific article published on October 2008

Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study

scientific article published on 24 May 2019

Genetics of Plasma Soluble Receptor for Advanced Glycation End-Products and Cardiovascular Outcomes in a Community-based Population: Results from the Atherosclerosis Risk in Communities Study

scientific article published on 17 June 2015

Genetics of blood pressure, hypertensive complications, and antihypertensive drug responses

scientific article

Genetics of hypertension, target-organ complications, and response to therapy.

scientific article

Genetics of primary hypertension.

scientific article

Genetics of ultrasonographic carotid atherosclerosis

scientific article published on 15 July 2004

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response

scientific article published on 21 November 2019

Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients

scientific article published on 9 March 2018

Genome partitioning of genetic variation for complex traits using common SNPs

scientific article

Genome scan for hypertension in nonobese African Americans: the National Heart, Lung, and Blood Institute Family Blood Pressure Program

scientific article published on 01 September 2004

Genome-Wide Association Approach Identified Novel Genetic Predictors of Heart Rate Response to β-Blockers

scientific article published on 24 February 2018

Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium

scientific article

Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study

article published in 2018

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels

Genome-Wide Association of Copy Number Polymorphisms and Kidney Function

scientific article

Genome-Wide Linkage Study of Erythrocyte Sodium-Lithium Countertransport

scientific article published on 01 May 2005

Genome-Wide Meta-Analysis of Blood Pressure Response to β1-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies)

scientific article published on 19 August 2019

Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response

scientific article published on January 2017

Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide.

scientific article published on 31 October 2016

Genome-wide Association Study Links APOEϵ4 and BACE1 Variants with Plasma Amyloid β Levels

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

scientific article published on 19 December 2016

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

scientific article published in Nature Communications

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans

scientific article

Genome-wide association analysis identifies multiple loci related to resting heart rate

scientific article

Genome-wide association analysis of incident coronary heart disease (CHD) in African Americans: a short report

scientific article

Genome-wide association and functional follow-up reveals new loci for kidney function

scientific article

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association scan of dental caries in the permanent dentition

scientific article

Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

scientific article

Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium

scientific article

Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium

scientific article

Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels

scientific article

Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction

scientific article

Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies

scientific article

Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin

scientific article published on 16 February 2013

Genome-wide association study identifies CAMKID variants involved in blood pressure response to losartan: the SOPHIA study.

scientific article published in September 2014

Genome-wide association study identifies GPC5 as a novel genetic locus protective against sudden cardiac arrest

scientific article

Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study

scientific article

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

scientific article published on 17 January 2018

Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism

scientific article

Genome-wide association study of PR interval

scientific article

Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study

scientific article published on 11 August 2013

Genome-wide association study of blood pressure and hypertension

scientific journal article

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project

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Genome-wide association study of retinopathy in individuals without diabetes

scientific article

Genome-wide distribution of ancestry in Mexican Americans.

scientific article

Genome-wide identification of allelic expression in hypertensive rats

scientific article published on 12 February 2009

Genome-wide linkage analyses for hypertension genes in two ethnically and geographically diverse populations

scientific article published in February 2003

Genome-wide linkage analysis for uric acid in families enriched for hypertension

scientific article published on 03 March 2009

Genome-wide linkage analysis reveals evidence of multiple regions that influence variation in plasma lipid and apolipoprotein levels associated with risk of coronary heart disease

scientific article published in June 2001

Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis

scientific article published in March 2005

Genome-wide linkage scans for loci affecting total cholesterol, HDL-C, and triglycerides: the Family Blood Pressure Program.

scientific article

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

scientific article published on 13 October 2017

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption

scientific article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

scientific article

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genome-wide significant locus of beta-trace protein, a novel kidney function biomarker, identified in European and African Americans

scientific article published on 16 January 2013

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Genomewide association studies of stroke

scientific article published on 15 April 2009

Genomic Association Analysis Reveals Variants Associated With Blood Pressure Response to Beta-Blockers in European Americans

scientific article published on 04 June 2019

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

scientific article published on 23 September 2016

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

scientific article published on 24 April 2017

Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker

scientific article

Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide

scientific article published on 10 June 2013

Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic

scientific article published on 30 June 2008

Genomic loci with pleiotropic effects on coronary artery calcification

scientific article published on 27 July 2005

Genomic regions that influence plasma levels of inflammatory markers in hypertensive sibships

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Genomic susceptibility Loci for brain atrophy, ventricular volume, and leukoaraiosis in hypertensive sibships

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Genomic susceptibility loci for brain atrophy in hypertensive sibships from the GENOA study

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Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium

scientific article

Genotype imputation of Metabochip SNPs using a study-specific reference panel of ~4,000 haplotypes in African Americans from the Women's Health Initiative

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Geographic Variation in Obesity at the State Level in the All of Us Research Program

scientific article published on 23 December 2021

Germline Cancer-Predisposition Variants in Pediatric Rhabdomyosarcoma: A Report from the Children's Oncology Group

scientific article published on 29 December 2020

Global DNA methylation and risk of subclinical atherosclerosis in young adults: The Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study ⬇️

scientific article published on October 2, 2011

Global transcriptional disturbances underlie Cornelia de Lange syndrome and related phenotypes

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Glucocorticoid Receptor Gene Variant in the 3′ Untranslated Region Is Associated with Multiple Measures of Blood Pressure

scientific article published in January 2009

Glucocorticoid receptor gene variant in the 3' untranslated region is associated with multiple measures of blood pressure

scientific article published on 14 October 2008

Glutathione S-transferase genotype as a susceptibility factor in smoking-related coronary heart disease

scientific article

Guidelines of the National Heart, Lung, and Blood Institute Working Group on Blood Drawing, Processing, and Storage for Genetic Studies

scientific article published on September 1996

HFE C282Y homozygotes have reduced low-density lipoprotein cholesterol: the Atherosclerosis Risk in Communities (ARIC) Study

scientific article published on 13 June 2008

HFE H63D Polymorphism and the Risk for Systemic Hypertension, Myocardial Remodeling, and Adverse Cardiovascular Events in the ARIC Study

scientific article published on 01 January 2019

Haplotype bolck linkage disequilibrium mapping

scientific article published on May 1, 2003

Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase

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Hepatic lipase promoter C-514T polymorphism influences serial changes in HDL cholesterol levels since childhood: the Bogalusa Heart Study

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Hepatocyte nuclear factor 1 and hypertensive nephropathy

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Heritability analysis of nontraditional glycemic biomarkers in the Atherosclerosis Risk in Communities Study

scientific article published on 19 June 2019

Heritability and genetic linkage of left ventricular mass, systolic and diastolic function in hypertensive African Americans (From the GENOA Study).

scientific article published on 6 May 2010

Heritability of coronary artery calcium quantity measured by electron beam computed tomography in asymptomatic adults

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Heritability of leukoaraiosis in hypertensive sibships

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High-Sensitivity Troponin I and Incident Coronary Events, Stroke, Heart Failure Hospitalization, and Mortality in the ARIC Study

scientific article published on 29 April 2019

High-resolution identity by descent mapping uncovers the genetic basis for blood pressure differences between spontaneously hypertensive rat lines

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High-sensitivity troponin T and cardiovascular events in systolic blood pressure categories: atherosclerosis risk in communities study

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High-throughput multiplex SNP genotyping with MALDI-TOF mass spectrometry: practice, problems and promise

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HindIII DNA polymorphism in the lipoprotein lipase gene and plasma lipid phenotypes and carotid artery atherosclerosis

scientific article published in November 1996

Homozygous and hemizygous CNV detection from exome sequencing data in a Mendelian disease cohort

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Homozygous loss-of-function mutations in SOHLH1 in patients with nonsyndromic hypergonadotropic hypogonadism

scientific article published on 16 March 2015

Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function

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Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016

scientific article

Human metabolome associates with dietary intake habits among African Americans in the atherosclerosis risk in communities study

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Hundreds of variants clustered in genomic loci and biological pathways affect human height

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Hydrochlorothiazide and atenolol combination antihypertensive therapy: effects of drug initiation order

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Hydrochlorothiazide-induced hyperuricaemia in the pharmacogenomic evaluation of antihypertensive responses study

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Hypertension in pregnancy as a risk factor for cardiovascular disease later in life

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Hypertension prevalence in the All of Us Research Program among groups traditionally underrepresented in medical research

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Hypertension susceptibility loci and blood pressure response to antihypertensives: results from the pharmacogenomic evaluation of antihypertensive responses study

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Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers

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Identification of Genetic Variants Linking Protein C and Lipoprotein Metabolism: The ARIC Study (Atherosclerosis Risk in Communities).

scientific article published on 12 January 2017

Identification of Rare Variants in Metabolites of the Carnitine Pathway by Whole Genome Sequencing Analysis

scientific article published on 3 June 2016

Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals

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Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout

scholarly article

Identification of likely pathogenic and known variants in TSPEAR, LAMB3, BCOR, and WNT10A in four Turkish families with tooth agenesis

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Identification, analysis, and interpretation of a human serum metabolomics causal network in an observational study

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Identifying Genes Whose Mutant Transcripts Cause Dominant Disease Traits by Potential Gain-of-Function Alleles

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Immunoglobulin Locus Associates with Serum IgG Levels and Albuminuria ⬇️

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Impact of Haplotype-Frequency Estimation Error on Test Statistics in Association Studies

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Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program

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Impact of abdominal obesity on incidence of adverse metabolic effects associated with antihypertensive medications

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Impact of adding a single allele in the 9p21 locus to traditional risk factors on reclassification of coronary heart disease risk and implications for lipid-modifying therapy in the Atherosclerosis Risk in Communities study

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Impact of genetic polymorphisms of SLC2A2, SLC2A5, and KHK on metabolic phenotypes in hypertensive individuals

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Impact of repeated measures and sample selection on genome-wide association studies of fasting glucose

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Impact of the Human Genome Project on Epidemiologic Research ⬇️

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Implementation of preemptive DNA sequence–based pharmacogenomics testing across a large academic medical center: The Mayo-Baylor RIGHT 10K Study

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Importance of Participant-Centricity and Trust for a Sustainable Medical Information Commons

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Imputing gene-treatment interactions when the genotype distribution is unknown using case-only and putative placebo analyses--a new method for the Genetics of Hypertension Associated Treatment (GenHAT) study

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In silico prediction of splice-altering single nucleotide variants in the human genome

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In silico tools for splicing defect prediction: a survey from the viewpoint of end users

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Inactivating mutations in NPC1L1 and protection from coronary heart disease

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Incident Heart Failure and Cognitive Decline: The Atherosclerosis Risk in Communities Study

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Increased CHIP Prevalence Amongst People Living with HIV

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Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

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Increased risk of incident stroke associated with the cyclooxygenase 2 (COX-2) G-765C polymorphism in African-Americans: the Atherosclerosis Risk in Communities Study

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Independent susceptibility markers for atrial fibrillation on chromosome 4q25.

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Inferring population mutation rate and sequencing error rate using the SNP frequency spectrum in a sample of DNA sequences

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Inflammatory protein levels and depression screening after coronary stenting predict major adverse coronary events

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Influence of genomic loci on measures of chronic kidney disease in hypertensive sibships

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Influence of lipoprotein lipase serine 447 stop polymorphism on tracking of triglycerides and HDL cholesterol from childhood to adulthood and familial risk of coronary artery disease: the Bogalusa heart study

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Influence of nitric oxide synthase gene polymorphism (G894T) on carotid artery intima-media thickness in adults: the Bogalusa Heart Study

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Influence of single nucleotide polymorphisms in factor VIII and von Willebrand factor genes on plasma factor VIII activity: the ARIC Study

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Inherited causes of clonal haematopoiesis in 97,691 whole genomes

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Innovation in Genomic Data Sharing at the NIH

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Insights into genetics, human biology and disease gleaned from family based genomic studies

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Insights into genetics, human biology and disease gleaned from family based genomic studies

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Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis

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Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence

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Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

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Interacting effects of gender and genotype on blood pressure response to hydrochlorothiazide

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Interaction between GSTT1 and GSTP1 allele variants as a risk modulating-factor for autism spectrum disorders

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Interaction between manganese and GSTP1 in relation to autism spectrum disorder while controlling for exposure to mixture of lead, mercury, arsenic, and cadmium

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Interaction between soluble thrombomodulin and intercellular adhesion molecule-1 in predicting risk of coronary heart disease

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Interaction between the NOS3 gene and obesity as a determinant of risk of type 2 diabetes: the Atherosclerosis Risk in Communities study

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Interaction effect of Serine447Stop variant of the lipoprotein lipase gene and C-514T variant of the hepatic lipase gene on serum triglyceride levels in young adults: the Bogalusa Heart Study ⬇️

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Interaction effects of high-density lipoprotein metabolism gene variation and alcohol consumption on coronary heart disease risk: the atherosclerosis risk in communities study.

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Interaction of Folate Intake and the Paraoxonase Q192R Polymorphism with Risk of Incident Coronary Heart Disease and Ischemic Stroke: The Atherosclerosis Risk in Communities Study ⬇️

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Interaction of G-protein beta3 subunit and nitric oxide synthase gene polymorphisms on carotid artery intima-media thickness in young adults: the Bogalusa Heart Study

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Interactions between the adducin 2 gene and antihypertensive drug therapies in determining blood pressure in people with hypertension

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Interactions between the single nucleotide polymorphisms in the homocysteine pathway (MTHFR 677C>T, MTHFR 1298 A>C, and CBSins) and the efficacy of HMG-CoA reductase inhibitors in preventing cardiovascular disease in high-risk patients of hypertensi

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Interactive effects between polymorphisms in the beta-adrenergic receptors and longitudinal changes in obesity

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Intercellular adhesion molecule-1 G241R polymorphism predicts risk of incident ischemic stroke: Atherosclerosis Risk in Communities study

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Investigating single nucleotide polymorphism (SNP) density in the human genome and its implications for molecular evolution

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Investigating the complex genetic architecture of ankle-brachial index, a measure of peripheral arterial disease, in non-Hispanic whites

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Ionizing radiation and genetic risks. VI. Chronic multifactorial diseases: a review of epidemiological and genetical aspects of coronary heart disease, essential hypertension and diabetes mellitus

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Is diabetes mellitus-linked amino acid signature associated with β-blocker-induced impaired fasting glucose?

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Is low-grade serous ovarian cancer part of the tumor spectrum of hereditary breast and ovarian cancer?

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Kininogen gene (KNG) variation has a consistent effect on aldosterone response to antihypertensive drug therapy: the GERA study

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Knowledge-driven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations

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LPL polymorphism predicts stroke risk in men

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Lack of agreement between office and ambulatory blood pressure responses to hydrochlorothiazide

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Lack of association between lipoprotein(a) and coronary artery calcification in the Genetic Epidemiology Network of Arteriopathy (GENOA) study

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Lack of association between polymorphisms in STK39, a putative thiazide response gene, and blood pressure response to hydrochlorothiazide

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Lack of association between uncoupling protein-2 Ala55Val polymorphism and incident diabetes in the atherosclerosis risk in communities study

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Lack of association of the angiotensinogen-6 polymorphism with blood pressure levels in the comprehensive NHLBI Family Blood Pressure Program. National Heart, Lung and Blood Institute

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Lack of correlation between thiazide-induced hyperglycemia and hypokalemia: subgroup analysis of results from the pharmacogenomic evaluation of antihypertensive responses (PEAR) study

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Lack of genetic linkage evidence for a trans-acting factor having a large effect on plasma lipoprotein[a] levels in African Americans ⬇️

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Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

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Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

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Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

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Large-scale association analysis identifies new risk loci for coronary artery disease

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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

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Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

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Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels

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Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels

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Launching genomics into the cloud: deployment of Mercury, a next generation sequence analysis pipeline

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Left ventricular hypertrophy after hypertensive pregnancy disorders.

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Length and sequence variation in the apolipoprotein B intron 20 Alu repeat.

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Lessons learned from additional research analyses of unsolved clinical exome cases

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Levels and Change in Galectin-3 and Association With Cardiovascular Events: The ARIC Study

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Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data

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Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease

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Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program

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Linkage analysis of candidate obesity genes among the Mexican-American population of Starr County, Texas

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Linkage analysis of plasma ApoE in three ethnic groups: multiple genes with context-dependent effects

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Linkage and association of adrenergic and dopamine receptor genes in the distal portion of the long arm of chromosome 5 with systolic blood pressure variation

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Linkage of hypertension to chromosome 2q14-q23 in Chinese families

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Linkage of the Wilson disease gene to chromosome 13 in North-American pedigrees

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Lipoprotein associated phospholipase A2 activity, apolipoprotein C3 loss-of-function variants and cardiovascular disease: The Atherosclerosis Risk In Communities Study

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Lipoprotein(a) levels and risk of cardiovascular disease events in individuals with diabetes mellitus or prediabetes: The Atherosclerosis Risk in Communities study

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Lipoprotein-associated phospholipase A2 and high-sensitivity C-reactive protein improve the stratification of ischemic stroke risk in the Atherosclerosis Risk in Communities (ARIC) study

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Lipoprotein-associated phospholipase A2 and risk of incident peripheral arterial disease: Findings from The Atherosclerosis Risk in Communities study (ARIC).

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Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident ischemic stroke in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study

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Lithium ion transport by erythrocytes of randomly selected blood donors and manic-depressive patients: lack of association with affective illness

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Loci influencing blood pressure identified using a cardiovascular gene-centric array

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Loci influencing blood pressure identified using a cardiovascular gene-centric array.

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Longitudinal analysis of haplotypes and polymorphisms of the APOA5 and APOC3 genes associated with variation in serum triglyceride levels: the Bogalusa Heart Study

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Longitudinal association of PCSK9 sequence variations with low-density lipoprotein cholesterol levels: the Coronary Artery Risk Development in Young Adults Study

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Longitudinal changes in triglycerides according to ANGPTL4[E40K] genotype and longitudinal body weight change in the atherosclerosis risk in communities study

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Loss of Function Mutations in NNT Are Associated With Left Ventricular Noncompaction

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Loss-of-function mutations in APOC3, triglycerides, and coronary disease

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Loss-of-function variants influence the human serum metabolome

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Low-density lipoprotein and high-density lipoprotein cholesterol levels in relation to genetic polymorphisms and menopausal status: the Atherosclerosis Risk in Communities (ARIC) Study

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Low-density lipoprotein particle size and coronary atherosclerosis in subjects belonging to hypertensive sibships

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Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

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MIPEP recessive variants cause a syndrome of left ventricular non-compaction, hypotonia, and infantile death

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MMP2 genetic variation is associated with measures of fibrous cap thickness: The Atherosclerosis Risk in Communities Carotid MRI Study

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Maternal Exposures Associated with Autism Spectrum Disorder in Jamaican Children.

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Maternal and Paternal Age are Jointly Associated with Childhood Autism in Jamaica ⬇️

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Matrix gla protein gene polymorphism is associated with increased coronary artery calcification progression

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Measuring alcohol consumption for genomic meta-analyses of alcohol intake: opportunities and challenges

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Measuring marker information content by the ambiguity of block boundaries observed in dense SNP data

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Medium-term variability of the human serum metabolome in the Atherosclerosis Risk in Communities (ARIC) study

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Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

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Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

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Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

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Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci

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Meta-analysis identifies six new susceptibility loci for atrial fibrillation

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Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

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Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

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Meta-analysis of genome-wide association data identifies two loci influencing age at menarche

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Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

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Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

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Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

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Metabolic and lifestyle determinants of postprandial lipemia differ from those of fasting triglycerides: The Atherosclerosis Risk In Communities (ARIC) study

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Metabolomic Associations of Asthma in the Hispanic Community Health Study/Study of Latinos

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Metabolomic Pattern Predicts Incident Coronary Heart Disease

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Metabolomic patterns and alcohol consumption in African Americans in the Atherosclerosis Risk in Communities Study

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Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population.

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Metabolomics and Incidence of Atrial Fibrillation in African Americans: The Atherosclerosis Risk in Communities (ARIC) Study

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Metabolomics and cognition in African American adults in midlife: the atherosclerosis risk in communities study

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Metabolomics and incident hypertension among blacks: the atherosclerosis risk in communities study

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Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells

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Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems

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MicroRNAs in the miR-17 and miR-15 families are downregulated in chronic kidney disease with hypertension

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Microcephaly, epilepsy, and neonatal diabetes due to compound heterozygous mutations in IER3IP1: insights into the natural history of a rare disorder

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Mining genetic epidemiology data with Bayesian networks I: Bayesian networks and example application (plasma apoE levels).

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Mining genetic epidemiology data with Bayesian networks application to APOE gene variation and plasma lipid levels

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Mining gold dust under the genome wide significance level: a two-stage approach to analysis of GWAS.

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Mitochondrial DNA Copy Number and Incident Heart Failure: The Atherosclerosis Risk in Communities (ARIC) Study

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Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs

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Moderate mutation rate in the SARS coronavirus genome and its implications

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Molecular Signature of Multisystem Cardiometabolic Stress and Its Association With Prognosis

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Molecular diagnostic experience of whole-exome sequencing in adult patients

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Molecular etiology of arthrogryposis in multiple families of mostly Turkish origin

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Molecular findings among patients referred for clinical whole-exome sequencing

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Monoallelic and Biallelic Variants in EMC1 Identified in Individuals with Global Developmental Delay, Hypotonia, Scoliosis, and Cerebellar Atrophy

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Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

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Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits

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Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

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Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

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Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

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Multi-ethnic genome-wide association study for atrial fibrillation

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Multiallelic Positions in the Human Genome: Challenges for Genetic Analyses

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Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

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Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI

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Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

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Multilocus effects of the renin-angiotensin-aldosterone system genes on blood pressure response to a thiazide diuretic

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Multiomics integrative analysis identifies allele-specific blood biomarkers associated to Alzheimer's disease etiopathogenesis

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Multiple SCN5A variant enhancers modulate its cardiac gene expression and the QT interval

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Multiple genes for essential-hypertension susceptibility on chromosome 1q.

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Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors

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Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population

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Multiple loci are associated with white blood cell phenotypes

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Multiple loci associated with indices of renal function and chronic kidney disease

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Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

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Multivariate genetic analysis of high density lipoprotein particles

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Multivariate linkage analysis of blood pressure and body mass index

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Mutations in PURA cause profound neonatal hypotonia, seizures, and encephalopathy in 5q31.3 microdeletion syndrome

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Mutations in VRK1 associated with complex motor and sensory axonal neuropathy plus microcephaly

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Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease

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Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis

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NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality

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NOS1AP variant associated with incidence of type 2 diabetes in calcium channel blocker users in the Atherosclerosis Risk in Communities (ARIC) study

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NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: the Atherosclerosis Risk in Communities study

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NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium

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Neighboring-nucleotide effects on single nucleotide polymorphisms: a study of 2.6 million polymorphisms across the human genome

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Neutral genomic regions refine models of recent rapid human population growth

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New Algorithm and Software (BNOmics) for Inferring and Visualizing Bayesian Networks from Heterogeneous Big Biological and Genetic Data

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New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

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New insights into the genetic etiology of Alzheimer's disease and related dementias

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New loci associated with kidney function and chronic kidney disease

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New mutations in the RAB28 gene in 2 Spanish families with cone-rod dystrophy

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New syndrome with retinitis pigmentosa is caused by nonsense mutations in retinol dehydrogenase RDH11.

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Night blood pressure responses to atenolol and hydrochlorothiazide in black and white patients with essential hypertension

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Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

Nitric oxide synthase gene polymorphism (G894T) influences arterial stiffness in adults: The Bogalusa Heart Study

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No association of apolipoprotein A-IV codon 347 and 360 variation with atherosclerosis and lipid transport in a sample of mixed hyperlipidemics

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No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects

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No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

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Normal Limits in Relation to Age, Body Size and Gender of Two-Dimensional Echocardiographic Aortic Root Dimensions in Persons ≥15 Years of Age ⬇️

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Novel Genetic Loci Associated With Retinal Microvascular Diameter

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Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index

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Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium

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Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

scientific article published on 18 June 2018

Novel genomic loci influencing plasma homocysteine levels

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Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

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Novel plasma biomarker of atenolol-induced hyperglycemia identified through a metabolomics-genomics integrative approach

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Nucleotide sequence analysis of the apolipoprotein B 3' VNTR

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OB gene not linked to human obesity in Mexican American affected sib pairs from Starr County, Texas

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Oligogenic heterozygosity in individuals with high-functioning autism spectrum disorders

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On Robust Association Testing for Quantitative Traits and Rare Variants.

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Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium

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P-selectin Thr715Pro polymorphism predicts P-selectin levels but not risk of incident coronary heart disease or ischemic stroke in a cohort of 14595 participants: the Atherosclerosis Risk in Communities Study

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PEHO Syndrome May Represent Phenotypic Expansion at the Severe End of the Early-Onset Encephalopathies.

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PGM3 mutations cause a congenital disorder of glycosylation with severe immunodeficiency and skeletal dysplasia

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PLD3 variants in population studies

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PNPLA3 polymorphisms and liver aminotransferase levels in a Mexican American population

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POGZ truncating alleles cause syndromic intellectual disability.

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PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

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PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

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PROX1 gene variant is associated with fasting glucose change after antihypertensive treatment

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PTPRD gene associated with blood pressure response to atenolol and resistant hypertension

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PacBio-LITS: a large-insert targeted sequencing method for characterization of human disease-associated chromosomal structural variations

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Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

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Parental history of stroke and myocardial infarction predicts coronary artery calcification: The Coronary Artery Risk Development in Young Adults (CARDIA) study

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Parliament2: Accurate structural variant calling at scale

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Pathway analysis with next-generation sequencing data

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Patterns and rates of exonic de novo mutations in autism spectrum disorders

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Pediatric data from the <i>All of Us</i> research program: demonstration of pediatric obesity over time

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Peeking under the peaks: following up genome-wide linkage analyses

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Peroxisome proliferator-activated receptor [alpha] genetic variation interacts with n-6 and long-chain n-3 fatty acid intake to affect total cholesterol and LDL-cholesterol concentrations in the Atherosclerosis Risk in Communities Study

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Personalized medicine for high blood pressure

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Pharmacogenetic Association of NOS3 Variants with Cardiovascular Disease in Patients with Hypertension: The GenHAT Study ⬇️

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Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT Study

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Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension

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Pharmacogenetic association of the angiotensin-converting enzyme insertion/deletion polymorphism on blood pressure and cardiovascular risk in relation to antihypertensive treatment: the Genetics of Hypertension-Associated Treatment (GenHAT) study

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Pharmacogenetic associations of MMP9 and MMP12 variants with cardiovascular disease in patients with hypertension

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Pharmacogenetic effect of the stromelysin (MMP3) polymorphism on stroke risk in relation to antihypertensive treatment: the genetics of hypertension associated treatment study

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Pharmacogenetic effects of 'candidate gene complexes' on stroke in the GenHAT study

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Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

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Pharmacogenetics of response to statins: where do we stand?

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Pharmacogenomic Genome-Wide Meta-Analysis of Blood Pressure Response to β-Blockers in Hypertensive African Americans

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Pharmacogenomics of antihypertensive drugs: rationale and design of the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) study

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Pharmacogenomics of hypertension: a genome‐wide, placebo‐controlled cross‐over study, using four classes of antihypertensive drugs

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Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing

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Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

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Plasma MCP-1 level and risk for peripheral arterial disease and incident coronary heart disease: Atherosclerosis Risk in Communities study

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Plasma Renin Activity Predicts Blood Pressure Responses to -Blocker and Thiazide Diuretic as Monotherapy and Add-On Therapy for Hypertension ⬇️

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Plasma dehydroepiandrosterone sulfate and cardiovascular disease risk in older men and women

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Plasma lipid, lipoprotein cholesterol, and apoprotein distributions in selected US communities. The Atherosclerosis Risk in Communities (ARIC) Study

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Plasma metabolomics and incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) Study

Plasma phospholipids and prevalence of mild cognitive impairment and/or dementia in the ARIC Neurocognitive Study (ARIC-NCS).

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Platelet Pl(A2) allele and incidence of coronary heart disease: results from the Atherosclerosis Risk In Communities (ARIC) Study

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Pleiotropic genes for metabolic syndrome and inflammation

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Pleiotropic genetic effects contribute to the correlation between HDL cholesterol, triglycerides, and LDL particle size in hypertensive sibships

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Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

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Polymorphic markers in apolipoprotein C-III gene flanking regions and hypertriglyceridemia

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Polymorphism in soluble epoxide hydrolase and blood pressure in spontaneously hypertensive rats

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Polymorphism of the soluble epoxide hydrolase is associated with coronary artery calcification in African-American subjects: The Coronary Artery Risk Development in Young Adults (CARDIA) study

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Polymorphisms in genes coding for GRK2 and GRK5 and response differences in antihypertensive-treated patients

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Polymorphisms in the ICAM1 gene predict circulating soluble intercellular adhesion molecule-1(sICAM-1).

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Polymorphisms within the C-Reactive Protein (CRP) Promoter Region Are Associated with Plasma CRP Levels

Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels

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Population genetics of hypervariable loci: analysis of PCR based VNTR polymorphism within a population

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Population genomic analysis of 962 whole genome sequences of humans reveals natural selection in non-coding regions.

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Population-based Risk Factors for Elevated Alanine Aminotransferase in a South Texas Mexican–American Population ⬇️

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Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL.

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Positional identification of hypertension susceptibility genes on chromosome 2.

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Possible race and gender divergence in association of genetic variations with plasma von Willebrand factor: a study of ARIC and 1000 genome cohorts

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Prediction of Coronary Heart Disease Risk using a Genetic Risk Score: The Atherosclerosis Risk in Communities Study

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Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study

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Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

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Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

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Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

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Rare coding TTN variants are associated with electrocardiographic QT interval in the general population

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Rare coding variants and X-linked loci associated with age at menarche

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Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease

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Rare variants analysis using penalization methods for whole genome sequence data

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Recurrent Muscle Weakness with Rhabdomyolysis, Metabolic Crises, and Cardiac Arrhythmia Due to Bi-allelic TANGO2 Mutations

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Regional association-based fine-mapping for sodium-lithium countertransport on chromosome 10.

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Relationship of alcohol consumption and type of alcoholic beverage consumed with plasma lipid levels: differences between Whites and African Americans of the ARIC study

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Risk of atherosclerosis: interaction of smoking and glutathione S-transferase genes

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Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study

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Role of BMI in the Association of the TCF7L2 rs7903146 Variant with Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study

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Role of metabolic genes in blood arsenic concentrations of Jamaican children with and without autism spectrum disorder

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SELP and SELPLG genetic variation is associated with cell surface measures of SELP and SELPLG: the Atherosclerosis Risk in Communities Carotid MRI Study

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SNP43 of CAPN10 and the risk of type 2 Diabetes in African-Americans: the Atherosclerosis Risk in Communities Study

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SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

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Screening for primary aldosteronism: implications of an increased plasma aldosterone/renin ratio.

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Seafood Consumption and Blood Mercury Concentrations in Jamaican Children With and Without Autism Spectrum Disorders ⬇️

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Sequence analysis of six blood pressure candidate regions in 4,178 individuals: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study

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Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene

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Sequence polymorphism at the human apolipoprotein AII gene ( APOA2): unexpected deficit of variation in an African-American sample

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Sequence variation in TMEM18 in association with body mass index: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

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Sequence variation in proprotein convertase subtilisin/kexin type 9 serine protease gene, low LDL cholesterol, and cancer incidence

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Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study

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Sequence variation in the soluble epoxide hydrolase gene and subclinical coronary atherosclerosis: interaction with cigarette smoking

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Sequence variation within the neuropeptide Y gene and obesity in Mexican Americans

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Sequence-Based Analysis of Lipid-Related Metabolites in a Multiethnic Study.

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Sequencing Analysis at 8p23 Identifies Multiple Rare Variants in DLC1 Associated with Sleep-Related Oxyhemoglobin Saturation Level

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Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

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Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

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Serum Metabolites Associated with Healthy Diets in African Americans and European Americans

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Serum Metabolomics and Incidence of Atrial Fibrillation (from the Atherosclerosis Risk in Communities Study)

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Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes

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Serum metabolomic profile of incident diabetes

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Serum metabolomic profiling and incident CKD among African Americans

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Serum sphingolipids and incident diabetes in a US population with high diabetes burden: the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

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Sex-specific differences in the effects of local androgen metabolism in the heart as an indicator for the risk of myocardial infarction

Signal peptide-length variation in human apolipoprotein B gene. Molecular characteristics and association with plasma glucose levels

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Single nucleotide polymorphisms associated with coronary heart disease predict incident ischemic stroke in the atherosclerosis risk in communities study

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Single nucleotide polymorphisms in cholesteryl ester transfer protein gene and recurrent coronary heart disease or mortality in patients with established atherosclerosis.

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Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans

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Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

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Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study

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Sorting nexin 1 loss results in increased oxidative stress and hypertension

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Specific P-selectin and P-selectin glycoprotein ligand-1 genotypes/haplotypes are associated with risk of incident CHD and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study

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Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics.

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Strategic transformation of population studies: recommendations of the working group on epidemiology and population sciences from the National Heart, Lung, and Blood Advisory Council and Board of External Experts

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Strategies for elucidating the phenotypic and genetic heterogeneity of a chronic disease with a complex etiology

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Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

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Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

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Studies of enzyme polymorphism in the Kamuela population of Drosophila mercatorum. III. Effects of variation at the alpha GPD locus and subflight stress on the energy charge and glycolytic intermediate concentrations

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Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

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Subsequent Event Risk in Individuals With Established Coronary Heart Disease

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Synergic effect of GSTP1 and blood manganese concentrations in Autism Spectrum Disorder

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Systems biology data analysis methodology in pharmacogenomics

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TCF7L2 single nucleotide polymorphisms, cardiovascular disease and all-cause mortality: the Atherosclerosis Risk in Communities (ARIC) study

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TCF7L2 variants associate with CKD progression and renal function in population-based cohorts

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TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.

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Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

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Targeted sequencing identifies a missense variant in the BEST3 gene associated with antihypertensive response to hydrochlorothiazide

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Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study

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The 9p21 genetic variant is additive to carotid intima media thickness and plaque in improving coronary heart disease risk prediction in white participants of the Atherosclerosis Risk in Communities (ARIC) Study

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The 9th Santorini Conference: Systems Medicine, Personalised Health and Therapy. "The Odyssey from Hope to Practice", Santorini, Greece, 30 September⁻3 October 2018

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The All of Us Research Program: Data quality, utility, and diversity

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The Alzheimer's Disease Sequencing Project: Study design and sample selection

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The Centers for Mendelian Genomics: a new large-scale initiative to identify the genes underlying rare Mendelian conditions.

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The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies

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The GENNID Study. A resource for mapping the genes that cause NIDDM.

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The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions

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The Genetic Basis of Mendelian Phenotypes: Discoveries, Challenges, and Opportunities

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The Genomics of Arthrogryposis, a Complex Trait: Candidate Genes and Further Evidence for Oligogenic Inheritance

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The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts

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The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

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The Loss of GSTM1 Associates with Kidney Failure and Heart Failure

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The Role of FREM2 and FRAS1 in the Development of Congenital Diaphragmatic Hernia

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The Ser(447)-Stop polymorphism of lipoprotein lipase is associated with variation in longitudinal serum high-density lipoprotein-cholesterol profiles: the Bogalusa Heart Study

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The US Cancer Moonshot initiative

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The amyloidogenic V122I transthyretin variant in elderly black Americans

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The association of cell cycle checkpoint 2 variants and kidney function: findings of the Family Blood Pressure Program and the Atherosclerosis Risk In Communities study

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The association of lipoprotein(a) with incident heart failure hospitalization: Atherosclerosis Risk in Communities study

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The association of podocin R229Q polymorphism with increased albuminuria or reduced estimated GFR in a large population-based sample of US adults

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The beta(2)-adrenergic receptor Arg16-gly polymorphism and interactions involving beta(2)- and beta(3)-adrenergic receptor polymorphisms are associated with variations in longitudinal serum lipid profiles: the Bogalusa Heart Study

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The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels

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The contribution of individual and pairwise combinations of SNPs in the APOA1 and APOC3 genes to interindividual HDL-C variability

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The diagnosis of autism and autism spectrum disorder in low- and middle-income countries: Experience from Jamaica.

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The effect of nine common polymorphisms in coagulation factor genes (F2, F5, F7, F12 and F13 ) on the effectiveness of statins: the GenHAT study

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The effect of variation in the apolipoprotein B gene on plasmid lipid and apolipoprotein B levels. I. A likelihood-based approach to cladistic analysis

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The effects of angiotensinogen gene polymorphisms on cardiovascular disease outcomes during antihypertensive treatment in the GenHAT study

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The effects of scale: variation in the APOA1/C3/A4/A5 gene cluster

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The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

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The impact of multiple single day blood pressure readings on cardiovascular risk estimation: The Atherosclerosis Risk in Communities study

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The performance of deleteriousness prediction scores for rare non-protein-changing single nucleotide variants in human genes

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The peroxisome proliferator-activated receptor-gamma2 gene polymorphism (Pro12Ala) beneficially influences insulin resistance and its tracking from childhood to adulthood: the Bogalusa Heart Study

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The relation of lipoprotein[a] concentrations and apolipoprotein[a] phenotypes with asymptomatic atherosclerosis in subjects of the Atherosclerosis Risk in Communities (ARIC) Study

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The role of drinking water sources, consumption of vegetables and seafood in relation to blood arsenic concentrations of Jamaican children with and without Autism Spectrum Disorders

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The role of plasma renin activity, age, and race in selecting effective initial drug therapy for hypertension

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The role of the genetics of sodium lithium countertransport in the determination of blood pressure variability in the population at large

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The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke

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The transcription factor 7-like 2 (TCF7L2) polymorphism may be associated with focal arteriolar narrowing in Caucasians with hypertension or without diabetes: the ARIC Study

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The use of measured genotype information in the analysis of quantitative phenotypes in man. II. The role of the apolipoprotein E polymorphism in determining levels, variability, and covariability of cholesterol, betalipoprotein, and triglycerides in

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The use of measured genotype information in the analysis of quantitative phenotypes in man. III. Simultaneous estimation of the frequencies and effects of the apolipoprotein E polymorphism and residual polygenetic effects on cholesterol, betalipopro

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The variable number of tandem repeat polymorphism of platelet glycoprotein Ibalpha and risk of coronary heart disease ⬇️

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Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

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Thrombomodulin Ala455Val polymorphism and risk of coronary heart disease

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Trans-ethnic Evaluation Identifies Novel Low Frequency Loci Associated with 25-Hydroxyvitamin D Concentrations.

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Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

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Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained

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Trans-ethnic meta-analysis of white blood cell phenotypes

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Transcription factor 7-like 2 (TCF7L2) polymorphism and context-specific risk of impaired fasting glucose in African American and Caucasian adults: the atherosclerosis risk in communities (ARIC) study

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Transcription factor 7-like 2 (TCF7L2) polymorphism and context-specific risk of type 2 diabetes in African American and Caucasian adults: the Atherosclerosis Risk in Communities study

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Transethnic meta-analysis suggests genetic variation in the HEME pathway influences potassium response in patients treated with hydrochlorothiazide

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Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource

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Tree scanning: a method for using haplotype trees in phenotype/genotype association studies

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Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium

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Troponin T and N-terminal pro-B-type natriuretic peptide: a biomarker approach to predict heart failure risk--the atherosclerosis risk in communities study

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Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

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Two polymorphisms for amino acid substitutions in the APOA4 gene

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Ultraconserved elements in the human genome: association and transmission analyses of highly constrained single-nucleotide polymorphisms

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Understanding the accuracy of statistical haplotype inference with sequence data of known phase

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Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies

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Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease

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Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

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Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

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Use of gene markers to guide antihypertensive therapy

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Use of wrapper algorithms coupled with a random forests classifier for variable selection in large-scale genomic association studies

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Usefulness of single nucleotide polymorphism in chromosome 4q25 to predict in-hospital and long-term development of atrial fibrillation and survival in patients undergoing coronary artery bypass grafting

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Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium

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Using multiple measures for quantitative trait association analyses: application to estimated glomerular filtration rate

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VNTR allele frequency distributions under the stepwise mutation model: a computer simulation approach

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Validated context-dependent associations of coronary heart disease risk with genotype variation in the chromosome 9p21 region: the Atherosclerosis Risk in Communities study

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Validity of the aldosterone-renin ratio used to screen for primary aldosteronism

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Variants for HDL-C, LDL-C, and triglycerides identified from admixture mapping and fine-mapping analysis in African American families

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Variants in CXADR and F2RL1 are associated with blood pressure and obesity in African-Americans in regions identified through admixture mapping

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Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry ⬇️

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Variation at the M235T locus of the angiotensinogen gene and essential hypertension: a population-based case-control study from Rochester, Minnesota

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Variation in ANGPTL4 and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study

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Variation in PCSK9, low LDL cholesterol, and risk of peripheral arterial disease

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Variation in TCF7L2 and increased risk of colon cancer: the Atherosclerosis Risk in Communities (ARIC) Study

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Variation in concentration of lipids, lipoprotein lipids, and apolipoproteins A-I and B in plasma from healthy women

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Variation in the Region of the Angiotensin-Converting Enzyme Gene Influences Interindividual Differences in Blood Pressure Levels in Young White Males ⬇️

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Variation in the checkpoint kinase 2 gene is associated with type 2 diabetes in multiple populations

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WGSA: an annotation pipeline for human genome sequencing studies.

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WNK1 kinase polymorphism and blood pressure response to a thiazide diuretic

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Whole Exome Sequencing in Atrial Fibrillation

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Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics

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Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study

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Whole exome sequencing identifies novel genes for fetal hemoglobin response to hydroxyurea in children with sickle cell anemia

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Whole exome sequencing identifies three novel mutations in ANTXR1 in families with GAPO syndrome

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Whole exome sequencing in 342 congenital cardiac left sided lesion cases reveals extensive genetic heterogeneity and complex inheritance patterns

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Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation

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Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

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Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium

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Whole genome sequence analysis of serum amino acid levels

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Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease.

scientific article published on 13 March 2018

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

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Whole-Exome Sequencing in Familial Parkinson Disease

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Whole-exome imputation of sequence variants identified two novel alleles associated with adult body height in African Americans.

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Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol

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Whole-exome sequencing reveals an inherited R566X mutation of the epithelial sodium channel β-subunit in a case of early-onset phenotype of Liddle syndrome

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Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program

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Whole-genome sequence-based analysis of high-density lipoprotein cholesterol

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Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program

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Whole-genome sequencing study of serum peptide levels: the Atherosclerosis Risk in Communities study

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Wolff-Parkinson-White syndrome: De novo variants and evidence for mutational burden in genes associated with atrial fibrillation

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beta2-adrenergic receptor polymorphism and venous thromboembolism.

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dbNSFP v2.0: a database of human non-synonymous SNVs and their functional predictions and annotations

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dbNSFP v3.0: A One-Stop Database of Functional Predictions and Annotations for Human Nonsynonymous and Splice-Site SNVs

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dbNSFP: A lightweight database of human nonsynonymous SNPs and their functional predictions ⬇️

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xAtlas: Scalable small variant calling across heterogeneous next-generation sequencing experiments

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β2 -Adrenergic Receptor Gene Affects the Heart Rate Response of β-Blockers: Evidence From 3 Clinical Studies

scientific article published on 14 May 2019

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