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List of works by Glen Spraggon

A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase

scientific journal article

Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations

scientific article

An Evolved Aminoacyl-tRNA Synthetase with Atypical Polysubstrate Specificity, ⬇️

scientific article published on March 22, 2011

Biochemical and structural characterization of the putative dihydropteroate synthase ortholog Rv1207 of Mycobacterium tuberculosis

scientific article

Characterization and optimization of selective, nonpeptidic inhibitors of cathepsin S with an unprecedented binding mode

scientific article

Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide

scientific article

Crystal Structure of Fragment Double-D from Human Fibrin with Two Different Bound Ligands, ⬇️

scientific article published on June 16, 1998

Crystal structure of 2-keto-3-deoxygluconate kinase (TM0067) from Thermotoga maritima at 2.05 A resolution

scientific article

Crystal structure of TM1030 from Thermotoga maritima at 2.3 A resolution reveals molecular details of its transcription repressor function

scientific article published in July 2007

Crystal structure of a putative oxalate decarboxylase (TM1287) from Thermotoga maritima at 1.95 A resolution

scientific journal article

Crystal structure of a recombinant α E C domain from human fibrinogen-420 ⬇️

scientific article published on August 4, 1998

Crystal structure of a transcription regulator (TM1602) from Thermotoga maritima at 2.3 A resolution

scientific article

Crystal structure of a two-subunit TrkA octameric gating ring assembly

scientific article published in 2015

Crystal structure of an iron-containing 1,3-propanediol dehydrogenase (TM0920) from Thermotoga maritima at 1.3 A resolution

scientific article

Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide

scientific article

Crystal structure of gamma-glutamyl phosphate reductase (TM0293) from Thermotoga maritima at 2.0 A resolution

scientific article

Crystal structure of human Pus10, a novel pseudouridine synthase

scientific article

Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain

scientific article

Crystal structure of the human neuropilin-1 b1 domain

scientific article

Crystal structure of uronate isomerase (TM0064) from Thermotoga maritima at 2.85 A resolution

scientific article

Crystal structures of MW1337R and lin2004: representatives of a novel protein family that adopt a four-helical bundle fold

scientific article

Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin ⬇️

scientific article published on October 2, 1997

Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design

scientific article

Efforts toward Expansion of the Genetic Alphabet:  Structure and Replication of Unnatural Base Pairs

scientific article

FdeC, a Novel Broadly Conserved Escherichia coli Adhesin Eliciting Protection against Urinary Tract Infections

scientific article

Genetic Incorporation of a Metal-Ion Chelating Amino Acid into Proteins as a Biophysical Probe

scientific article

Integration of inositol phosphate signaling pathways via human ITPK1

scientific article

Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in Staphylococcus aureus

scientific article

Structural Basis of Murein Peptide Specificity of a γ-D-Glutamyl-L-Diamino Acid Endopeptidase

scientific article

Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197 ⬇️

scientific article published on March 19, 2012

Structure analysis of peptide deformylases from Streptococcus pneumoniae, Staphylococcus aureus, Thermotoga maritima and Pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase

scientific article

Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824

scientific article

Structure of a copper-mediated base pair in DNA

scientific article

Supramolecular Organization of the Repetitive Backbone Unit of the Streptococcus pneumoniae Pilus

scientific article

The crystal structure of anthranilate phosphoribosyltransferase from the enterobacterium Pectobacterium carotovorum

scientific article

The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain

scientific article

The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, L-tryptophan

scientific article

The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site

scientific article

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