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List of works by Markku Laakso

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Analysis of protein-coding genetic variation in 60,706 humans

scientific article (publication date: 17 August 2016)
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

scientific article (publication date: 3 May 2001)
Mortality from Coronary Heart Disease in Subjects with Type 2 Diabetes and in Nondiabetic Subjects with and without Prior Myocardial Infarction

scientific article (publication date: 23 July 1998)
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

scientific article
Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial

scientific article (publication date: 8 October 2005)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)
Genetic studies of body mass index yield new insights for obesity biology

scientific article
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011
Discovery and refinement of loci associated with lipid levels

scientific article
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

scientific article
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

scientific article
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scientific article
Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial

scientific article published on 26 November 2005
Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article
Common variants at 30 loci contribute to polygenic dyslipidemia

scientific article
Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial

scientific article
Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012
Genome-wide association study identifies eight loci associated with blood pressure

scientific article (publication date: June 2009)
Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial

scientific article
Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial

scientific article
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article
A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

scientific article
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article
New genetic loci link adipose and insulin biology to body fat distribution

scientific article
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article
Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary: The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD)

article published 13 June 2006 in European Heart Journal
Variants in MTNR1B influence fasting glucose levels

scientific article
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012
Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man. A novel mechanism for insulin resistance

scientific article
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

scientific article
The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)
Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2): effects on mortality and morbidity

scientific article published on 23 February 2005
Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article
Integrative approaches for large-scale transcriptome-wide association studies

scientific article published on 8 February 2016
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

scientific article published in June 2009
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome

scientific article
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article
Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1).

scientific article published on 29 February 2004
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

scientific article
Effect of valsartan on the incidence of diabetes and cardiovascular events

scientific article
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

scientific article
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

scientific article
Medial artery calcification. A neglected harbinger of cardiovascular complications in non-insulin-dependent diabetes mellitus

scientific article published on August 1996
Safety and Feasibility of Catheter-Based Local Intracoronary Vascular Endothelial Growth Factor Gene Transfer in the Prevention of Postangioplasty and In-Stent Restenosis and in the Treatment of Chronic Myocardial Ischemia

scientific article published on May 12, 2003
Association between features of the insulin resistance syndrome and alzheimer's disease independently of apolipoprotein e4 phenotype: cross sectional population based study

scientific article published on October 25, 1997
Effect of nateglinide on the incidence of diabetes and cardiovascular events

scientific article published on 14 March 2010

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