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List of works by Jack Satsangi

A plea for TDM-based optimisation for treatment of Crohn's disease - Authors' reply

scientific article published on 12 January 2017

A randomised, double-blind, parallel-group trial to assess mercaptopurine versus placebo to prevent or delay recurrence of Crohn’s disease following surgical resection (TOPPIC)

scholarly article published 27 September 2017

A role for vimentin in Crohn disease

scientific article published on 28 August 2012

Advances in IBD genetics

scientific article published on 11 March 2014

Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis

article

Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways

scientific article

Association of DLG5 and inflammatory bowel disease across populations

scientific article

Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP-2, with outcome of HCV infection

scientific article

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

scientific article

Autologous Haematopoietic Stem Cell Transplantation for Crohn's Disease: A Retrospective Survey of Long-term Outcomes From the European Society for Blood and Marrow Transplantation

scientific article published on 01 August 2018

Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial

scientific article published on December 2015

Autologous stem cell transplantation in refractory Crohn's disease - low intensity therapy evaluation (ASTIClite): study protocols for a multicentre, randomised controlled trial and observational follow up study.

scientific article

Autologous stem-cell transplantation in treatment-refractory Crohn's disease: an analysis of pooled data from the ASTIC trial

scientific article

Azathioprine and anti-TNF alpha therapies in Crohn's disease: a review of pharmacology, clinical efficacy and safety

scientific article

Barrett's esophagus: evolutionary insights from genomics

scientific article published on 21 February 2013

Bayesian refinement of association signals for 14 loci in 3 common diseases

scientific article published on 28 October 2012

Beyond gene discovery in inflammatory bowel disease: the emerging role of epigenetics.

scientific article published on 08 June 2013

Biomarkers in Search of Precision Medicine in IBD.

scientific article published on 27 September 2016

Blood-based DNA methylation in Crohn's disease and severity of intestinal inflammation

scientific article published on 26 November 2019

COVID-19 and Gastrointestinal Disease. Implications for the Gastroenterologist

scientific article published on 09 October 2020

Can Thiopurines Prevent Formation of Antibodies Against Tumor Necrosis Factor Antagonists After Failure of These Therapies?

scientific article published on 05 October 2016

Changes to serum sample tube and processing methodology does not cause Intra-Individual [corrected] variation in automated whole serum N-glycan profiling in health and disease

scientific article

Characterisation of osteoprotegerin autoantibodies in coeliac disease

scientific article published on 20 June 2015

Characterization of intestinal gene expression profiles in Crohn's disease by genome-wide microarray analysis.

scientific article published in October 2010

Cigarette smoke extract (CSE) delays NOD2 expression and affects NOD2/RIPK2 interactions in intestinal epithelial cells

scientific article

Clinical utility and diagnostic accuracy of faecal calprotectin for IBD at first presentation to gastroenterology services in adults aged 16-50 years

scientific article published on January 2015

Common variants at five new loci associated with early-onset inflammatory bowel disease

scientific article

Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects

scientific article

Contribution of CARD15 variants in determining susceptibility to Crohn's disease in Sweden

scientific article published on 01 June 2006

Contribution of the IBD5 locus to Crohn's disease in the Swedish population

scientific article published on 01 February 2007

Copy number variation of scavenger-receptor cysteine-rich domains within DMBT1 and Crohn's disease

scientific article published on 27 January 2016

Correction: changes to serum sample tube and processing methodology does not cause inter-individual variation in automated whole serum N-glycan profiling in health and disease

scientific article published on June 2015

Crohn's disease

scientific article published on 19 November 2014

Cyclooxygenase-2 (COX-2) polymorphisms and risk of inflammatory bowel disease in a Scottish and Danish case-control study

scientific article

Danish cohort of monozygotic inflammatory bowel disease twins: Clinical characteristics and inflammatory activity

scientific article published on 7 June 2016

De-escalation of immunomodulator and biological therapy in inflammatory bowel disease

scientific article published on 01 January 2020

De-escalation of medical therapy in inflammatory bowel disease

scientific article published on 04 November 2020

Definition of phenotypic characteristics of childhood-onset inflammatory bowel disease

scientific article

Detailed haplotype-tagging study of germline variation of MUC19 in inflammatory bowel disease.

scientific article

Disease location, anti-Saccharomyces cerevisiae antibody, and NOD2/CARD15 genotype influence the progression of disease behavior in Crohn's disease

scientific article published on 01 September 2004

Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease

scientific article

Does cigarette smoking influence the phenotype of Crohn's disease? Analysis using the Montreal classification

scientific article published on 01 March 2007

Does nicotine influence cytokine profile and subsequent cell cycling/apoptotic responses in inflammatory bowel disease?

scientific article published in November 2008

Dysregulation of human beta-defensin-2 protein in inflammatory bowel disease

scientific article

Early combined immunosuppression in Crohn's disease

Erratum: Corrigendum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scholarly article published in Nature Genetics

Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7.

scientific article published on 9 January 2017

Fecal microbiota profiles in treatment-naïve pediatric inflammatory bowel disease - associations with disease phenotype, treatment, and outcome

scholarly article by Christine Olbjørn et al published 2019 in Clinical and Experimental Gastroenterology

Fine-mapping inflammatory bowel disease loci to single-variant resolution

scientific article

Gene discovery in IBD: a decade of progress

scientific article published on April 2008

Genes in inflammatory bowel disease: lessons from complex diseases

scientific article published on 01 February 2011

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

scientific article published on 27 April 2008

Genetic sharing and heritability of paediatric age of onset autoimmune diseases.

scientific article

Genetic variation in the familial Mediterranean fever gene (MEFV) and risk for Crohn's disease and ulcerative colitis

scientific article

Genetics of childhood-onset inflammatory bowel disease

scientific article published on January 2011

Genetics of inflammatory bowel disease: implications for disease pathogenesis and natural history.

scientific article published on October 2009

Genetics of the innate immune response in inflammatory bowel disease

scientific article published on March 2007

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

scientific article

Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease.

scientific article published on 9 January 2017

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

article

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.

scientific article published on 9 January 2017

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

scientific article

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

scientific article

Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway

scientific article published on 21 October 2011

Genotype-phenotype analysis in childhood-onset Crohn's disease: NOD2/CARD15 variants consistently predict phenotypic characteristics of severe disease

scientific article published on 01 November 2005

HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants.

scientific article published on 14 September 2014

Haplotype-Tagging Analysis of Common Variants of the IL23R Gene Demonstrates Gene-wide Extent of Association with IBD ⬇️

scientific article published on 01 May 2013

Hedgehog, paneth cells, and colon cancer: a cautionary note for the use of systemic agonists/antagonists

scientific article published on 01 November 2006

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

scientific article

How to Apply for and Secure EU Funding for Collaborative IBD Research Projects

scientific article published on 07 January 2016

IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease

scientific article

Incidence of juvenile-onset Crohn's disease in Scotland: association with northern latitude and affluence

scientific article published in October 2004

Inflammatory Bowel Disease Through the Lens of Single-cell RNA-seq Technologies

scientific article published on 09 May 2020

Inflammatory bowel disease associates with proinflammatory potential of the immunoglobulin G glycome

scientific article published on June 2015

Infliximab use in Crohn's disease: impact on health care resources in the UK.

scientific article published in October 2005

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

scientific article

Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship

scientific article

Investigation of NOD1/CARD4 variation in inflammatory bowel disease using a haplotype-tagging strategy

scientific article published on 05 July 2007

Just another flare of ulcerative colitis?

scientific article published on 13 January 2020

Killing of Escherichia coli by Crohn's Disease Monocyte-derived Macrophages and Its Enhancement by Hydroxychloroquine and Vitamin D

scientific article published on July 2015

Letter: rationalising aminosalicylates in inflammatory bowel disease-authors' reply

scientific article published on 01 November 2020

Lymphoma Risk and Overall Safety Profile of Adalimumab in Patients With Crohn's Disease With up to 6 Years of Follow-Up in the Pyramid Registry

scientific article published on 05 June 2018

Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease.

scientific article

Mercaptopurine versus placebo to prevent recurrence of Crohn's disease after surgical resection (TOPPIC): a multicentre, double-blind, randomised controlled trial.

scientific article published on 30 August 2016

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

scientific article

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

scientific article

Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD

scientific article published on 01 September 2018

Molecular genetics in gastroenterology: from research success to clinical application?

scientific article

Molecular genetics of Crohn's disease

scientific article published on June 2004

More pediatric NOD2/CARD data

scientific article

Multidrug resistance (MDR1) gene in inflammatory bowel disease: a key player?

scientific article

Mutational Analysis Identifies Therapeutic Biomarkers in Inflammatory Bowel Disease-Associated Colorectal Cancers

scientific article published on 27 June 2018

NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2

scientific article (publication date: July 2012)

Nationwide linkage analysis in Scotland-Has mortality following hospital admission for Crohn's disease changed in the early 21st century?

scientific article published on 26 September 2014

Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

scientific article

New genes in inflammatory bowel disease: lessons for complex diseases?

scientific article

Novel susceptibility genes in inflammatory bowel disease

scientific article

Paneth cell marker CD24 in NOD2 knockout organoids and in inflammatory bowel disease (IBD).

scientific article published on 23 May 2013

Pathogenesis of Crohn's disease

scientific article published on 2 April 2015

PepT1 oligopeptide transporter (SLC15A1) gene polymorphism in inflammatory bowel disease

scientific article

Pharmacogenetics and inflammatory bowel disease: progress and prospects.

scientific article published on March 2004

Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes

scientific article

Potential role for the common cystic fibrosis ΔF508 mutation in Crohnʼs disease

scientific article published on 01 May 2007

Precision medicine in inflammatory bowel disease: concept, progress and challenges

scientific article published on 28 January 2020

Predicting outcome in acute severe colitis - controversies in clinical practice in 2021

scientific article published on 03 January 2021

Predicting outcomes in acute severe ulcerative colitis

scientific article published on 15 December 2014

Predicting the need for colectomy in severe ulcerative colitis: a critical appraisal of clinical parameters and currently available biomarkers ⬇️

scientific article published on January 1, 2011

Prevalence of CARD15/NOD2 mutations in Caucasian healthy people

scientific article

Promoter methylation of the MGAT3 and BACH2 genes correlates with the composition of the immunoglobulin G glycome in inflammatory bowel disease.

scientific article published on 4 June 2018

Purine metabolism controls innate lymphoid cell function and protects against intestinal injury.

scientific article

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

scientific article

Real-World Effectiveness of Tofacitinib for Moderate to Severe Ulcerative Colitis: A Multi-Centre UK Experience

scientific article published on 13 April 2020

Reply to Daly and Rioux response

Resolution of non-small-cell lung cancer after withdrawal of anti-TNF therapy

scientific article published on 01 July 2008

Review article: impact of cigarette smoking on intestinal inflammation-direct and indirect mechanisms

scientific article published on 05 May 2020

Review article: withdrawal of 5-aminosalicylates in inflammatory bowel disease

scientific article published on 26 May 2020

Rising incidence of pediatric inflammatory bowel disease in Scotland.

scientific article

Role of infliximab in ulcerative colitis: further questions

scientific article published on 01 April 2006

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

scientific article (publication date: July 2007)

Sero-reactivity to microbial components in Crohn's disease is associated with disease severity and progression, but not NOD2/CARD15 genotype

scientific article published on 01 December 2004

Serum C-reactive protein and CRP genotype in pediatric inflammatory bowel disease: influence on phenotype, natural history, and response to therapy

scientific article published on 01 March 2015

Serum Calprotectin: A Novel Diagnostic and Prognostic Marker in Inflammatory Bowel Diseases

scientific article

Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.

scientific article published in March 2018

Sight-threatening keratopathy complicating anti-TNF therapy in Crohn's disease: a case report

scientific article published on 01 January 2014

Single nucleotide polymorphisms that increase expression of the guanosine triphosphatase RAC1 are associated with ulcerative colitis

scientific article published on 4 May 2011

Smoking habit and load influence age at diagnosis and disease extent in ulcerative colitis

scientific article published on 01 March 2007

Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease

scientific article published on 21 February 2020

Systematic Review of Effects of Withdrawal of Immunomodulators or Biologic Agents From Patients With Inflammatory Bowel Disease

scientific article published on 14 September 2015

Systematic meta-analyses and field synopsis of genetic and epigenetic studies in paediatric inflammatory bowel disease

scientific article published on 27 September 2016

Systematic review: the role of breastfeeding in the development of pediatric inflammatory bowel disease

scientific article

TLE1 modifies the effects of NOD2 in the pathogenesis of Crohn's disease

scientific article

Technology insight: the application of proteomics in gastrointestinal disease

scientific article

The ACE (Albumin, CRP and Endoscopy) Index in Acute Colitis: A Simple Clinical Index on Admission that Predicts Outcome in Patients With Acute Ulcerative Colitis

scientific article published on 23 June 2020

The Contribution of OCTN1/2 Variants Within the IBD5 Locus to Disease Susceptibility and Severity in Crohn’s Disease

scientific article published on 01 December 2005

The Inflammatory Bowel Disease Drug Azathioprine Induces Autophagy via mTORC1 and the Unfolded Protein Response Sensor PERK

scientific article published on 01 August 2019

The clinical course of ulcerative colitis after orthotopic liver transplantation for primary sclerosing cholangitis: further appraisal of immunosuppression post transplantation

scientific article published on 01 December 2005

The genetics of Crohn's disease

scientific article published on January 2009

The genetics of inflammatory bowel disease

scientific article published on 25 September 2007

The hedgehog signalling pathway in the gastrointestinal tract: implications for development, homeostasis, and disease

scientific article

The impact of different DNA extraction kits and laboratories upon the assessment of human gut microbiota composition by 16S rRNA gene sequencing

scientific article

The intermediate filament protein, vimentin, is a regulator of NOD2 activity

scientific article

The role of genetics in Crohn's disease: how could it influence future therapies?

article

The role of glycosylation in IBD.

scientific article

The type III intermediate filament vimentin regulates organelle distribution and modulates autophagy

scientific article published in PLoS ONE

Therapeutic decisions in inflammatory bowel disease in the SARS-Cov-2 pandemic

scientific article published on 15 June 2020

Therapeutic options in acute severe ulcerative colitis

scientific article published on June 2008

Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology

scientific article

Tuberous sclerosis‐2 (TSC2) regulates the stability of death‐associated protein kinase‐1 (DAPK) through a lysosome‐dependent degradation pathway ⬇️

scientific article published on December 6, 2010

Two-stage genome-wide methylation profiling in childhood-onset Crohn's Disease implicates epigenetic alterations at the VMP1/MIR21 and HLA loci.

scientific article published on October 2014

Use of methotrexate in refractory Crohn's disease: the Edinburgh experience

scientific article

Variation in ICOSLG influences Crohn's disease susceptibility

scientific article published on 18 February 2011

What do the terms "genetic predisposition" and "genetic heterogeneity" mean in relation to inflammatory bowel disease?

scientific article

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