List of works - Manuela Uda

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

scientific article

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

scientific article

Common variants at 30 loci contribute to polygenic dyslipidemia

scientific article

Common variants near MC4R are associated with fat mass, weight and risk of obesity

scientific article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

scientific article

Variants in MTNR1B influence fasting glucose levels

scientific article

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

scientific article published in June 2009

Identification of ten loci associated with height highlights new biological pathways in human growth

scientific article

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

scientific article published in June 2009

DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

scholarly article

Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia

scientific article

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

scientific article

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

scientific article published on 16 October 2011

Common variants at ten loci modulate the QT interval duration in the QTSCD Study

scientific article

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

Genome-wide association study of PR interval

scientific article

Common variants in the GDF5-UQCC region are associated with variation in human height

scientific article

Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development

scientific journal article

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Genetic loci influencing kidney function and chronic kidney disease

scientific article

The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts

scientific article

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

scientific article

Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations

scientific article

Foxl2 is required for commitment to ovary differentiation

scientific journal article

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

scientific article published on 11 September 2011

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

scientific article

Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability

scientific article

Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis

scientific journal article

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

Genome-wide association scan of trait depression

scientific journal article

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia

scientific article

Facets of personality linked to underweight and overweight

scientific article published on 04 May 2009

IRAK-M is involved in the pathogenesis of early-onset persistent asthma

scientific article

Genome-wide association analysis identifies multiple loci related to resting heart rate

scientific article

Amelioration of Sardinian beta0 thalassemia by genetic modifiers

scientific article

A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation

scientific article

BDNF Val66Met is associated with introversion and interacts with 5-HTTLPR to influence neuroticism

scientific article

Foxl2 functions in sex determination and histogenesis throughout mouse ovary development

scientific article published on 18 June 2009

Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function

scientific article published on June 2008

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

scientific article

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

scientific article

List of works by Manuela Uda

Biological, clinical and population relevance of 95 loci for blood lipids

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

Common variants at 30 loci contribute to polygenic dyslipidemia

Common variants near MC4R are associated with fat mass, weight and risk of obesity

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

Variants in MTNR1B influence fasting glucose levels

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

Identification of ten loci associated with height highlights new biological pathways in human growth

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

Common variants at ten loci modulate the QT interval duration in the QTSCD Study

New gene functions in megakaryopoiesis and platelet formation

Genome-wide association study of PR interval

Common variants in the GDF5-UQCC region are associated with variation in human height

Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development

Seventy-five genetic loci influencing the human red blood cell

Genetic loci influencing kidney function and chronic kidney disease

The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations

Foxl2 is required for commitment to ovary differentiation

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability

Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis

A genome-wide association search for type 2 diabetes genes in African Americans

Genome-wide association scan of trait depression

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia

Facets of personality linked to underweight and overweight

IRAK-M is involved in the pathogenesis of early-onset persistent asthma

Genome-wide association analysis identifies multiple loci related to resting heart rate

Amelioration of Sardinian beta0 thalassemia by genetic modifiers

A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation

BDNF Val66Met is associated with introversion and interacts with 5-HTTLPR to influence neuroticism

Foxl2 functions in sex determination and histogenesis throughout mouse ovary development

Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers