List of works - Markus Perola

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Systematic identification of trans eQTLs as putative drivers of known disease associations

scientific article (publication date: October 2013)

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

scientific article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

scientific article

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Genome-wide association study identifies 74 loci associated with educational attainment

scientific article published on 11 May 2016

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

Identification of seven loci affecting mean telomere length and their association with disease

scientific article published on April 2013

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

scientific article published in June 2009

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

scientific article published on 21 June 2013

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

scientific article

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

scientific article

Heritability of adult body height: a comparative study of twin cohorts in eight countries

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

scientific article

A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses

scientific article

Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism

scientific article

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

scientific journal article

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

scientific article published on 26 June 2011

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

scientific article published on 2 March 2016

Distribution and medical impact of loss-of-function variants in the Finnish founder population

scientific article

Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts

scientific article

The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies

scientific article

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The transcriptional landscape of age in human peripheral blood

scientific article

The impact of low-frequency and rare variants on lipid levels

scientific article published on 11 May 2015

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

scientific article

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

scientific article published on 23 March 2016

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Geographic differences in genetic susceptibility to IgA nephropathy: GWAS replication study and geospatial risk analysis

scientific article

Metabonomic, transcriptomic, and genomic variation of a population cohort

scientific article

Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: an observational study of 17,345 persons

scientific article

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits

scientific journal article

Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017

List of works by Markus Perola

Biological, clinical and population relevance of 95 loci for blood lipids

Genetic studies of body mass index yield new insights for obesity biology

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Discovery and refinement of loci associated with lipid levels

Systematic identification of trans eQTLs as putative drivers of known disease associations

Defining the role of common variation in the genomic and biological architecture of adult human height

Large-scale association analysis identifies new risk loci for coronary artery disease

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

New genetic loci link adipose and insulin biology to body fat distribution

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

Genome-wide association study identifies 74 loci associated with educational attainment

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

Identification of seven loci affecting mean telomere length and their association with disease

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

Common variants associated with plasma triglycerides and risk for coronary artery disease

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

Heritability of adult body height: a comparative study of twin cohorts in eight countries

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways

A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses

Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

Rare and low-frequency coding variants alter human adult height

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

Distribution and medical impact of loss-of-function variants in the Finnish founder population

Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts

The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

The transcriptional landscape of age in human peripheral blood

The impact of low-frequency and rare variants on lipid levels

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Geographic differences in genetic susceptibility to IgA nephropathy: GWAS replication study and geospatial risk analysis

Metabonomic, transcriptomic, and genomic variation of a population cohort

Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: an observational study of 17,345 persons

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits

Exome-wide association study of plasma lipids in >300,000 individuals