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List of works by Slobodan Paessler

A novel, rapid assay for detection and differentiation of serotype-specific antibodies to Venezuelan equine encephalitis complex alphaviruses.

scientific article published on June 2005

A simple method for calculation of basic molecular properties of nutrients and their use as a criterion for a healthy diet

scientific article

A single mutation (V64G) within the RING Domain of Z attenuates Junin virus

scientific article published on 25 September 2020

A substitution in the transmembrane region of the glycoprotein leads to an unstable attenuation of Machupo virus

scientific article published on 16 July 2014

A viral RNA structural element alters host recognition of nonself RNA

scientific article

Absence of an N-Linked Glycosylation Motif in the Glycoprotein of the Live-Attenuated Argentine Hemorrhagic Fever Vaccine, Candid #1, Results in Its Improper Processing, and Reduced Surface Expression

scientific article published on 6 February 2017

Adenoviral vector-based vaccine is fully protective against lethal Lassa fever challenge in Hartley guinea pigs

scientific article published on 24 September 2019

Alpha-beta T cells provide protection against lethal encephalitis in the murine model of VEEV infection

scientific article

Animal Model of Sensorineural Hearing Loss Associated with Lassa Virus Infection.

scientific article

Animal Models of Lassa Fever

scientific article published on 06 March 2020

Antiviral activities of type I interferons to SARS-CoV-2 infection

scientific article published on 29 April 2020

Antiviral activity of a small-molecule inhibitor of arenavirus glycoprotein processing by the cellular site 1 protease

scientific article

Auditory function analysis in immunodeficient STAT1 knock-out mice: considerations for viral infection models

scientific article published on 15 October 2020

CD4 T-cell depletion prevents Lassa fever associated hearing loss in the mouse model

scientific article published in 2022

CD4+ T cells provide protection against acute lethal encephalitis caused by Venezuelan equine encephalitis virus

scientific article published on 03 May 2009

CDK9-Dependent Transcriptional Elongation in the Innate Interferon-Stimulated Gene Response to Respiratory Syncytial Virus Infection in Airway Epithelial Cells ⬇️

scientific article published on April 17, 2013

COVID-19 Orf3b protein: the putative biological function and the therapeutic target

scientific article published on 25 February 2020

Characterization of lethal dengue virus type 4 (DENV-4) TVP-376 infection in mice lacking both IFN-α/β and IFN-γ receptors (AG129) and comparison with the DENV-2 AG129 mouse model

scientific article

Chimeric Sindbis/eastern equine encephalitis vaccine candidates are highly attenuated and immunogenic in mice

scientific article

Cocaine evokes a profile of oxidative stress and impacts innate antiviral response pathways in astrocytes

scientific article published on 22 March 2018

Comparative analysis of the alphavirus-based vectors expressing Rift Valley fever virus glycoproteins

scientific article

Confocal Imaging of Double-Stranded RNA and Pattern Recognition Receptors in Negative-Sense RNA Virus Infection

scientific article published on 26 January 2019

Control of SIV infection and subsequent induction of pandemic H1N1 immunity in rhesus macaques using an Ad5 [E1-, E2b-] vector platform

scientific article

Current small animal models for LASV hearing loss

scientific article published on 31 August 2019

Differential Immune Responses to Hemorrhagic Fever-Causing Arenaviruses

scientific article published on 02 October 2019

Drug Repurposing for Candidate SARS-CoV-2 Main Protease Inhibitors by a Novel In Silico Method

scientific article published on 23 August 2020

Ebola Virus and Marburg Virus in Human Milk Are Inactivated by Holder Pasteurization

scientific article

Efficacy of a novel iodine complex solution, CupriDyne, in inactivating SARS-CoV-2

scientific article published on 09 May 2020

Encephalitic alphaviruses

scientific article

Envelope glycoprotein mutations mediate equine amplification and virulence of epizootic venezuelan equine encephalitis virus

scientific article published on July 2005

Epidemiology and pathogenesis of Bolivian hemorrhagic fever

scientific article

Evolution of 2014/15 H3N2 Influenza Viruses Circulating in US: Consequences for Vaccine Effectiveness and Possible New Pandemic.

scientific article

Experimental Everglades virus infection of cotton rats (Sigmodon hispidus)

scientific article

Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats

scientific article published on 09 March 2020

Functional Interferon System Is Required for Clearance of Lassa Virus ⬇️

scientific article published on January 11, 2012

Generation and characterization of closely related epizootic and enzootic infectious cDNA clones for studying interferon sensitivity and emergence mechanisms of Venezuelan equine encephalitis virus

scientific article

Glycoprotein N-linked glycans play a critical role in arenavirus pathogenicity

scientific article published on 01 March 2021

High heart rate at admission as a predictive factor of mortality in hospitalized patients with Lassa fever: An observational cohort study in Sierra Leone

scientific article published on 03 February 2020

Highly Pathogenic New World Arenavirus Infection Activates the Pattern Recognition Receptor Protein Kinase R without Attenuating Virus Replication in Human Cells

scientific article published on 09 August 2017

Highly Pathogenic New World and Old World Human Arenaviruses Induce Distinct Interferon Responses in Human Cells

scientific article published on 29 April 2015

Host immunity in the protective response to vaccination with heat-killed Burkholderia mallei

scientific article

Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection

scientific article published on 17 June 2020

Ibuprofen as a template molecule for drug design against Ebola virus

scientific article published on January 2018

Improving attrition rates in Ebola virus drug discovery

scientific article published on 30 June 2015

In silico analysis suggests repurposing of ibuprofen for prevention and treatment of EBOLA virus disease

scientific article published on May 2015

In vitro anti-influenza activity of in silico repurposed candidate drug cycrimine

scientific article published on 28 February 2020

In vitro efficacy of a copper iodine complex PPE disinfectant for SARS-CoV-2 inactivation

scientific article published on 03 July 2020

In vivo imaging systems (IVIS) detection of a neuro-invasive encephalitic virus

scientific article published on 2 December 2012

Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers

scientific article (publication date: 5 July 2008)

Injectable peramivir mitigates disease and promotes survival in ferrets and mice infected with the highly virulent influenza virus, A/Vietnam/1203/04 (H5N1)

scientific article

Innate immune response to arenaviral infection: a focus on the highly pathogenic New World hemorrhagic arenaviruses.

scientific article published on 26 September 2013

Junín Virus Infection Activates the Type I Interferon Pathway in a RIG-I-Dependent Manner ⬇️

scientific article published on May 22, 2012

Junín virus pathogenesis and virus replication

scientific article

Lassa Fever 2016 Outbreak in Plateau State, Nigeria-The Changing Epidemiology and Clinical Presentation

scholarly article by Nathan Y Shehu et al published 2018 in Frontiers in Public Health

Lassa Virus Reverse Genetics

scientific article published on January 2017

Lassa Virus but Not Highly Pathogenic New World Arenaviruses Restrict Immunostimulatory dsRNA Accumulation During Infection

scientific article published on 12 February 2020

Lassa fever-induced sensorineural hearing loss: A neglected public health and social burden

scientific article published on 22 February 2018

Lassa virus diversity and feasibility for universal prophylactic vaccine

scientific article published on 31 January 2019

Lassa virus isolates from Mali and the Ivory Coast represent an emerging fifth lineage

scientific article

Lethal Infection of Lassa Virus Isolated from a Human Clinical Sample in Outbred Guinea Pigs without Adaptation

scientific article published on 25 September 2019

Live, Attenuated Venezuelan Equine Encephalitis Virus Vaccine (TC83) Causes Persistent Brain Infection in Mice with Non-functional αβ T-Cells

scientific article published on 26 January 2017

Luminore CopperTouch™ surface coating effectively inactivates SARS-CoV-2, Ebola and Marburg viruses in vitro

scientific article published on 14 July 2020

MAVS is essential for primary CD4+ T cell immunity but not for recall T cell responses following an attenuated West Nile virus infection

scientific article (publication date: 11 January 2017)

Machupo Virus Expressing GPC of the Candid#1 Vaccine Strain of Junin Virus Is Highly Attenuated and Immunogenic

scientific article

Merimepodib, an IMPDH inhibitor, suppresses replication of Zika virus and other emerging viral pathogens

scientific article published on 7 November 2017

Mice Lacking Functional STAT1 Are Highly Susceptible to Lethal Infection with Lassa Virus ⬇️

scientific article published on July 31, 2013

Mice lacking alpha/beta and gamma interferon receptors are susceptible to junin virus infection

scientific article

Monoclonal Antibodies with Neutralizing Activity and Fc-Effector Functions against the Machupo Virus Glycoprotein

scientific article published on 14 February 2020

Mouse Model of Neurological Complications Resulting from Encephalitic Alphavirus Infection.

scientific article

Natural killer cell mediated pathogenesis determines outcome of central nervous system infection with Venezuelan equine encephalitis virus in C3H/HeN mice ⬇️

scientific article published on April 21, 2012

Neurological Sequelae Resulting from Encephalitic Alphavirus Infection

scientific article

Neuropathology of H5N1 virus infection in ferrets

scientific article published on 2 December 2011

Neuropsychological, Neurovirological and Neuroimmune Aspects of Abnormal GABAergic Transmission in HIV Infection

scientific article published on 30 January 2016

Noncytopathic replication of Venezuelan equine encephalitis virus and eastern equine encephalitis virus replicons in Mammalian cells

scientific article

Novel linear DNA vaccines induce protective immune responses against lethal infection with influenza virus type A/H5N1.

scientific article

One Health epidemic preparedness: Biosafety quality improvement training in Nigeria

scientific article published in 2023

PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection

scientific article

Pathogenesis of Venezuelan equine encephalitis ⬇️

scientific article published on July 22, 2013

Pathogenesis of XJ and Romero strains of Junin virus in two strains of guinea pigs.

scientific article

Pathogenesis of the viral hemorrhagic fevers

scientific article

Possible repurposing of seasonal influenza vaccine for prevention of Zika virus infection

scientific article

Potent Antiviral Activities of Type I Interferons to SARS-CoV-2 Infection

scientific article published on 5 April 2020

Potent inhibition of Junín virus infection by interferon in murine cells

scientific article

Predicted Enhanced Human Propensity of Current Avian-Like H1N1 Swine Influenza Virus from China

scientific article

Prediction of influenza vaccine effectiveness for the influenza season 2017/18 in the US.

scientific article published on 29 November 2017

Prevention of influenza virus shedding and protection from lethal H1N1 challenge using a consensus 2009 H1N1 HA and NA adenovirus vector vaccine ⬇️

scientific article published on August 5, 2011

Production of IL-8, IL-17, IFN-gamma and IP-10 in human astrocytes correlates with alphavirus attenuation

scientific article published on 11 January 2013

Protection of mice by equine herpesvirus type 1 based experimental vaccine against lethal Venezuelan equine encephalitis virus infection in the absence of neutralizing antibodies.

scientific article published in January 2008

RIG-I enhanced interferon independent apoptosis upon Junin virus infection

scientific article

Rapid, non-invasive imaging of alphaviral brain infection: Reducing animal numbers and morbidity to identify efficacy of potential vaccines and antivirals ⬇️

scientific article published on October 12, 2011

Reactive astrogliosis in response to hemorrhagic fever virus: microarray profile of Junin virus-infected human astrocytes

scientific article

Recombinant alphaviruses are safe and useful serological diagnostic tools.

scientific article published on April 2007

Recombinant sindbis/Venezuelan equine encephalitis virus is highly attenuated and immunogenic

scientific article published on September 2003

Replication and clearance of Venezuelan equine encephalitis virus from the brains of animals vaccinated with chimeric SIN/VEE viruses

scientific article

Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic Romero and live-attenuated Candid #1 strains of Junin virus, the causative agent of Argentine hemorrhagic fever disease

scientific article

Rescue of a recombinant Machupo virus from cloned cDNAs and in vivo characterization in interferon (αβ/γ) receptor double knockout mice

scientific article

Resequencing of the Puumala virus strain Sotkamo from the WHO Arbovirus collection ⬇️

scientific article published on July 15, 2012

Reverse Transcription-PCR-Enzyme-Linked Immunosorbent Assay for Rapid Detection and Differentiation of Alphavirus Infections

scientific article (publication date: November 2006)

Review of Biology and Replication

article

Sequelae of Lassa Fever: Postviral Cerebellar Ataxia

scientific article published on 03 December 2019

Simple Chemoinformatics Criterion Using Electron Donor-Acceptor Molecular Characteristics for Selection of Antibiotics Against Multi-Drug-Resistant Bacteria

scientific article published on 01 October 2016

Superior efficacy of a recombinant flagellin:H5N1 HA globular head vaccine is determined by the placement of the globular head within flagellin.

scientific article

Susceptibility of the Aotus nancymaae owl monkey to eastern equine encephalitis

scientific article published on 30 January 2009

TC83 replicon vectored vaccine provides protection against Junin virus in guinea pigs

scientific article

The Biological Rationale for the Repurposing of BCG Vaccine against SARS-CoV-2

scientific article published on 14 August 2020

The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines

scientific article published on 05 August 2020

The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines

scientific article published on 26 November 2020

The Ectodomain of Glycoprotein from the Candid#1 Vaccine Strain of Junin Virus Rendered Machupo Virus Partially Attenuated in Mice Lacking IFN-αβ/γ Receptor

scientific article

The Glycoprotein of the Live-Attenuated Junin Virus Vaccine Strain Induces Endoplasmic Reticulum Stress and Forms Aggregates prior to Degradation in the Lysosome

scientific article published on 31 March 2020

The IMPDH inhibitor merimepodib suppresses SARS-CoV-2 replication in vitro

scientific article published on 09 April 2020

The Old World and New World alphaviruses use different virus-specific proteins for induction of transcriptional shutoff

scientific article published on 15 November 2006

The glycoprotein precursor gene of Junin virus determines the virulence of the Romero strain and the attenuation of the Candid #1 strain in a representative animal model of Argentine hemorrhagic fever

scientific article published on 25 March 2015

The hamster as an animal model for eastern equine encephalitis--and its use in studies of virus entrance into the brain

scientific article published on 6 May 2004

The pathogenesis of severe fever with thrombocytopenia syndrome virus infection in alpha/beta interferon knockout mice: insights into the pathologic mechanisms of a new viral hemorrhagic fever

scientific article

Use of the informational spectrum methodology for rapid biological analysis of the novel coronavirus 2019-nCoV: prediction of potential receptor, natural reservoir, tropism and therapeutic/vaccine target

scientific article published on 27 January 2020

Using electronic biology based platform to predict flu vaccine efficacy for 2018/2019.

scientific article published on 8 March 2018

Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses.

scientific article

Vaccines for Venezuelan equine encephalitis

scientific article

Variation in interferon sensitivity and induction among strains of eastern equine encephalitis virus

scientific article

Venezuelan encephalitis emergence mediated by a phylogenetically predicted viral mutation

scientific article

Venezuelan equine encephalitis virus in the guinea pig model: evidence for epizootic virulence determinants outside the E2 envelope glycoprotein gene.

scientific article published in March 2005

Venezuelan equine encephalitis virus infection of spiny rats

scientific article published in May 2005

Virtual Screen for Repurposing of Drugs for Candidate Influenza a M2 Ion-Channel Inhibitors

scientific article published on 26 March 2019

Visualization of Double-Stranded RNA Colocalizing With Pattern Recognition Receptors in Arenavirus Infected Cells

scholarly article by Elizabeth J Mateer et al published 2018 in Frontiers in cellular and infection microbiology

Vγ4+T cells regulate host immune response to West Nile virus infection ⬇️

scientific article published on November 1, 2011

Zika virus infection elicits auto-antibodies to C1q.

scientific article published on 30 January 2018

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