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List of works by Fernando Rivadeneira

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article

25-hydroxyvitamin D concentrations during fetal life and bone health in children aged 6 years: a population-based prospective cohort study

scientific article

A Large-Scale Population-Based Analysis of Common Genetic Variation in the Thyroid Hormone Receptor Alpha Locus and Bone

scholarly article by Marco Medici et al published February 2012 in Thyroid

A Meta-Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAX.

scientific article published on 24 October 2015

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A child with a deletion in the monocarboxylate transporter 8 gene: 7-year follow-up and effects of thyroid hormone treatment

scientific article published on 6 September 2011

A de novo 14q12q13.3 interstitial deletion in a patient affected by a severe neurodevelopmental disorder of unknown origin

scientific article

A genetic epidemiologic study of candidate genes involved in the optic nerve head morphology

scientific article

A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies

scientific article published on 12 June 2012

A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk

scientific article published on January 2014

A genome-wide approach to children's aggressive behavior: The EAGLE consortium

scientific article published on 18 June 2015

A genome-wide association meta-analysis identifies new childhood obesity loci

scientific article

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation

scientific article

A genome-wide association meta-analysis of preschool internalizing problems.

scientific article published on 19 February 2014

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14.

scientific article

A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22

scientific journal article

A genome-wide association study identifies five loci influencing facial morphology in Europeans

scientific article

A genome-wide association study of acenocoumarol maintenance dosage.

scientific article published on 4 July 2009

A genome-wide association study of corneal astigmatism: The CREAM Consortium

scientific article published on 5 February 2018

A genome-wide association study of early menopause and the combined impact of identified variants

scientific article published on 9 January 2013

A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.

scientific article

A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation

scientific article

A genome-wide association study of optic disc parameters

scientific article

A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus.

scientific article published on 16 December 2013

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

scientific article

A large genome scan for rare CNVs in amyotrophic lateral sclerosis

scientific article

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

scientific article

A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

scientific article

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

scientific article

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.

scientific article

A meta-analysis of the association of fracture risk and body mass index in women

scientific article published on January 2014

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function

scientific article

A novel common variant in DCST2 is associated with length in early life and height in adulthood

scientific article published on 3 October 2014

A polymorphic CA repeat in the IGF-I gene is associated with gender-specific differences in body height, but has no effect on the secular trend in body height

scientific article

A polymorphism in the AMH type II receptor gene is associated with age at menopause in interaction with parity

article

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A simple risk score for the assessment of absolute fracture risk in general practice based on two longitudinal studies

scientific article published on May 2009

A systematic evaluation of 151 candidate genes for their association with osteoporosis and osteoporotic fracture in a meta-analysis of genome-wide association data

article

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

scientific article published on 01 October 2019

A variant in MCF2L is associated with osteoarthritis

scientific article

ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure

scientific article published on 30 January 2015

Adverse outcomes of frailty in the elderly: the Rotterdam Study

scientific article

An Atlas of Human and Murine Genetic Influences on Osteoporosis

An atlas of genetic influences on osteoporosis in humans and mice

scientific article published on 31 December 2018

An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population

scientific article

Ancestry and dental development: A geographic and genetic perspective

scientific article published on 15 November 2017

Assessment of gene-by-sex interaction effect on bone mineral density

scientific article (publication date: October 2012)

Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies

scientific article

Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study

scientific article published in the British Medical Journal

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)

Association analyses of 47,500 individuals identifies six fracture loci and 82 BMD loci clustering in biological pathways that regulate osteoblast and osteoclast activity

Association between Bone Mass and Dental Hypomineralization

scientific article published on 8 January 2016

Association between an insulin-like growth factor I gene promoter polymorphism and bone mineral density in the elderly: the Rotterdam Study

scientific article

Association between bone mineral density and type 2 diabetes mellitus: a meta-analysis of observational studies

scientific article

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

scientific article published on 23 December 2011

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study

scientific article published on 04 September 2019

Association of Circulating Wnt Antagonists With Severe Abdominal Aortic Calcification in Elderly Women

scientific article published on 12 January 2017

Association of HSP70 and its co-chaperones with Alzheimer's disease

scientific article

Association of adiposity genetic variants with menarche timing in 92,105 women of European descent

scientific article published on 04 April 2013

Association of anthropometric measures with fat and fat-free mass in the elderly: The Rotterdam study

scientific article

Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD.

scientific article

Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium

scientific journal article

Association of heat shock proteins with Parkinson's disease

scientific article published on 26 November 2011

Association of lumbar disc degeneration with osteoporotic fractures; the Rotterdam study and meta-analysis from systematic review

scientific article published on 17 August 2013

Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts

scientific article published on April 2009

Association of polymorphisms in the beta-2 adrenergic receptor gene with fracture risk and bone mineral density

scientific article published on 25 April 2015

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

scientific article

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

article

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Associations of breast-feeding patterns and introduction of solid foods with childhood bone mass: The Generation R Study

scientific article published on 9 February 2016

Author Correction: An atlas of genetic influences on osteoporosis in humans and mice

scientific article published on 01 May 2019

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles

scientific article (publication date: 9 December 2013)

BMD Loci Contribute to Ethnic and Developmental Differences in Skeletal Fragility across Populations: Assessment of Evolutionary Selection Pressures

scientific article

BMP-2 gene polymorphisms and osteoporosis: the Rotterdam Study

scientific article (publication date: June 2006)

Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium

scientific article

Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

scientific article

Body composition by dual-energy X-ray absorptiometry in women with previous pre-eclampsia or small-for-gestational-age offspring

article

Bone Mass and Strength in School-Age Children Exhibit Sexual Dimorphism Related to Differences in Lean Mass: The Generation R Study

scientific article published on 24 November 2015

Bone health and coronary artery calcification: The Rotterdam Study

scientific article published on 9 February 2015

Bone mineral density and chronic lung disease mortality: the rotterdam study

scientific article published on 25 February 2014

Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.

scientific article published on May 2008

Bone parameters across different types of hip osteoarthritis and their relationship to osteoporotic fracture risk

scientific article published in March 2013

Bringing Genomic Discoveries to the Clinic: Integrating Omic Data Into the Musculoskeletal Field Through International Teamwork and Collaboration

scientific article published on 26 August 2020

C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis

scientific article

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

scientific article published on 29 September 2017

Candidate gene studies and the quest for the entrepreneurial gene

article

Cell Specific eQTL Analysis without Sorting Cells

scientific article published on 8 May 2015

Cell specific eQTL analysis without sorting cells

Challenges in conducting genome-wide association studies in highly admixed multi-ethnic populations: the Generation R Study

scientific article

Clinical Implications of Old and New Genes for Open-Angle Glaucoma

article

Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture

scientific article

Common DNA variants predict tall stature in Europeans

scientific article published on 20 November 2013

Common Genetic Determinants of Vitamin D Insufficiency: A Genome-Wide Association Study

Common Genetic Variation of the Low-Density Lipoprotein Receptor-Related Protein 5 and 6 Genes Determines Fracture Risk in Elderly White Men

article

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common genetic determinants of intraocular pressure and primary open-angle glaucoma

scientific article

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

scientific article

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

scientific article

Common genetic variants associate with serum phosphorus concentration

scientific article

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

scientific article

Common genetic variants associated with open-angle glaucoma

scientific article published on 22 March 2011

Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium

scientific article published on 8 November 2011

Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: results of a meta-analysis

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Common variants at 12q15 and 12q24 are associated with infant head circumference

scientific article published on 15 April 2012

Common variants at 6q22 and 17q21 are associated with intracranial volume

scientific article published on 15 April 2012

Common variants at ten loci influence QT interval duration in the QTGEN Study

scientific article published on 22 March 2009

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

scientific article

Common variants in Mendelian kidney disease genes and their association with renal function

scientific article published on 12 September 2013

Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis

scientific article published on 24 October 2008

Common variation near ROBO2 is associated with expressive vocabulary in infancy.

scientific article

Consortium genome-wide meta-analysis for childhood dental caries traits

Consortium-based genome-wide meta-analysis for childhood dental caries traits

scholarly article by Simon Haworth published in September 2018

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

scientific article published on 27 July 2009

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: Susceptibility to chronic mucus hypersecretion, a genome wide association study

scientific article published on 29 May 2015

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Correlation between genetic and geographic structure in Europe

scientific article

Corrigendum to “A genome-wide association study identifies a common variant near the GPR22 gene as a new locus involved in prevalence and progression of osteoarthritis” [Bone. 44S2 (2009) S224]

article

Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article published on 26 May 2017

Corrigendum: Rare coding variants and X-linked loci associated with age at menarche

scientific article published on 17 December 2015

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Degenerative inter-vertebral disc disease osteochondrosis intervertebralis in Europe: prevalence, geographic variation and radiological correlates in men and women aged 50 and over

scientific article published on 7 April 2017

Design of a frailty index among community living middle-aged and older people: The Rotterdam study

scientific article published on 12 December 2016

Development of a Food Group-Based Diet Score and Its Association with Bone Mineral Density in the Elderly: The Rotterdam Study

scientific article

Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study

scientific article published on 02 July 2020

Diabetes, diabetic complications, and fracture risk

scientific article

Dietary acid load in early life and bone health in childhood: the Generation R Study.

scientific article published on 4 November 2015

Dietary acid load, trabecular bone integrity, and mineral density in an ageing population: the Rotterdam study

scientific article published on 12 April 2017

Dietary fat composition, total body fat and regional body fat distribution in two Caucasian populations of middle-aged and older adult women

scientific article published on 28 September 2016

Dietary patterns explaining differences in bone mineral density and hip structure in the elderly: the Rotterdam Study

scientific article published on 30 November 2016

Dietary patterns in an elderly population and their relation with bone mineral density: the Rotterdam Study

scientific article published on 24 August 2016

Dietary vitamin A intake and bone health in the elderly: the Rotterdam Study

scientific article published on 16 September 2015

Digital quantification of human eye color highlights genetic association of three new loci

scientific article

Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

scientific article published on 26 September 2016

Discovery and refinement of loci associated with lipid levels

scientific article

Discovery of novel heart rate-associated loci using the Exome Chip

scientific article

Disentangling the genetics of lean mass

article

Dissecting the relationship between high-sensitivity serum C-reactive protein and increased fracture risk: the Rotterdam Study

scientific article published on 13 December 2013

Distinct Subsets of Noncoding RNAs Are Strongly Associated With BMD and Fracture, Studied in Weight-Bearing and Non-Weight-Bearing Human Bone

scientific article published on 03 February 2020

Diversity, compositional and functional differences between gut microbiota of children and adults

scientific article published on 23 January 2020

Does fetal smoke exposure affect childhood bone mass? The Generation R Study

scientific article published on 9 January 2015

Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval

scientific article published on 05 March 2013

Dual energy x-ray absorptiometry analysis contributes to the prediction of hip osteoarthritis progression

scientific article

Education influences the role of genetics in myopia

scientific article published on 19 October 2013

Effect of dietary B vitamins on BMD and risk of fracture in elderly men and women: the Rotterdam study

scientific article published on 17 August 2007

Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations

scientific article

Effects of serum TSH and FT4 levels and the TSHR-Asp727Glu polymorphism on bone: the Rotterdam Study

Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms

scientific article

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies

scientific article published on 14 October 2011

Epigenome-wide Association of DNA Methylation in Whole Blood With Bone Mineral Density

scientific article published on 10 April 2017

Erratum: Common variants at 12q15 and 12q24 are associated with infant head circumference

scholarly article published in Nature Genetics

Erratum: Common variants at 6q22 and 17q21 are associated with intracranial volume

article

Erratum: Dietary vitamin A intake and bone health in the elderly: the Rotterdam Study

article

Erratum: Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

article

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Estimation of Genetic Relationships Between Individuals Across Cohorts and Platforms: Application to Childhood Height

scientific article

Estrogen receptor alpha polymorphisms and postmenopausal breast cancer risk

scientific article

Estrogen receptor beta (ESR2) polymorphisms in interaction with estrogen receptor alpha (ESR1) and insulin-like growth factor I (IGF1) variants influence the risk of fracture in postmenopausal women

scientific article published in September 2006

Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus

scientific article published in October 2017

Evidence of inbreeding depression on human height

scientific article

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

scientific article

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

Fast linear mixed model computations for genome-wide association studies with longitudinal data

scientific article

Femoral neck BMD is a strong predictor of hip fracture susceptibility in elderly men and women because it detects cortical bone instability: the Rotterdam Study

scientific article

Fetal and childhood growth patterns associated with bone mass in school-age children: the Generation R Study

scientific article

Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

scientific article

Foetal, neonatal and child vitamin D status and enamel hypomineralization

scientific article

Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo

scientific article published in October 2010

Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants

scientific article

Fractures are not in genes – Authors' reply

scientific article published in The Lancet

GRIMP: a web- and grid-based tool for high-speed analysis of large-scale genome-wide association using imputed data

scientific article

GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium

scientific article

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

scientific article published in Nature Communications

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

scientific article published on 21 June 2013

GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

scientific article published on 03 May 2019

GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy

scientific article

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

scientific article published on 04 September 2019

GWAS with longitudinal phenotypes: performance of approximate procedures

scientific article published on 25 February 2015

Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways

scientific article

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia

scientific article

Genetic Determinants of Circulating Estrogen Levels, and Evidence of a Causal Effect of Estradiol on Bone Density in Men.

scientific article published on 9 January 2018

Genetic Determinants of Osteoporosis

Genetic Determinants of Osteoporosis

Genetic Polymorphism of miR-196a-2 is Associated with Bone Mineral Density (BMD).

scientific article published on 25 November 2017

Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity

Genetic architecture of open angle glaucoma and related determinants

scientific article published on 7 November 2010

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic basis of falling risk susceptibility in the UK Biobank Study

scientific article published on 30 September 2020

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

scientific article

Genetic determinants of mortality. Can findings from genome-wide association studies explain variation in human mortality?

scientific article published on 25 January 2013

Genetic determinants of serum testosterone concentrations in men.

scientific article

Genetic evidence of assortative mating in humans

article

Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

scientific article published on 13 November 2020

Genetic loci for retinal arteriolar microcirculation

scientific article

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic taste blindness to bitter and body composition in childhood: a Mendelian randomization design

scientific article

Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data

scientific article

Genetic variants associated with type 2 diabetes and adiposity and risk of intracranial and abdominal aortic aneurysms

scientific article published on 5 April 2017

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genetic variants in the ADAMTS13 and SUPT3H genes are associated with ADAMTS13 activity

article

Genetic variants of FOXP3 influence graft survival in kidney transplant patients

scientific article

Genetic variation in the GDF5 region is associated with osteoarthritis, height, hip axis length and fracture risk: the Rotterdam study

scientific article published on 24 November 2008

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

scientific article published on 26 June 2011

Genetics of Bone and Muscle Interactions in Humans

article

Genetics of Osteoporotic Vertebral Fractures

scientific article published on 12 September 2015

Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up

scientific article published on 12 May 2015

Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

scientific article

Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium

scientific article

Genome-Wide Association Study of Vascular Dementia

scholarly article by Elisabeth M.C. Schrijvers et al published February 2012 in Stroke Journal

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels

Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent

scientific article published on 21 September 2017

Genome-wide Analysis of Large-scale Longitudinal Outcomes using Penalization —GALLOP algorithm

scientific article published in May 2018

Genome-wide Association Study for Radiographic Vertebral Fractures: A Potential Role for the 16q24 BMD Locus versus Lessons Learned from Challenging Phenotype Definition

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

scientific article published in Nature Communications

Genome-wide analysis of genetic loci associated with Alzheimer disease

scientific article

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

scientific article

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

scientific article published on 25 July 2016

Genome-wide association analysis identifies multiple loci related to resting heart rate

scientific article

Genome-wide association analysis identifies six new loci associated with forced vital capacity

scientific article

Genome-wide association analysis identifies susceptibility loci for migraine without aura

scientific article

Genome-wide association analysis identifies three new breast cancer susceptibility loci

scientific article published on 22 January 2012

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

scientific article published on 24 November 2015

Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM

scientific article

Genome-wide association and functional follow-up reveals new loci for kidney function

scientific article

Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand

scientific article published on 30 August 2017

Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis

scientific journal article

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

scientific article

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genome-wide association meta-analysis for total serum bilirubin levels

scientific article

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

scientific article published on 28 May 2018

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

scientific article

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

scientific article published in June 2009

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

scientific article published in April 2013

Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area

article

Genome-wide association studies in economics and entrepreneurship research: promises and limitations

scholarly article by Philipp D. Koellinger et al published 13 May 2010 in Small Business Economics

Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium

scientific article

Genome-wide association study confirms extant PD risk loci among the Dutch

scientific article

Genome-wide association study for acute otitis media in children identifies FNDC1 as disease contributing gene

scientific article published on 28 September 2016

Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus

scientific article

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium

scientific article

Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis

scientific article

Genome-wide association study identifies 48 common genetic variants associated with handedness

scientific article published on 28 September 2020

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited

scientific article

Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero

scientific article published on 12 April 2018

Genome-wide association study identifies novel breast cancer susceptibility loci

scientific article published on 28 June 2007

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations

scientific article

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels

scientific article published on 17 January 2018

Genome-wide association study in an admixed case series reveals IL12A as a new candidate in Behçet disease

scientific article

Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

scientific article

Genome-wide association study of PR interval

scientific article

Genome-wide association study of blood pressure and hypertension

scientific journal article

Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3

scientific article

Genome-wide association study of kidney function decline in individuals of European descent

scientific article

Genome-wide association study of retinopathy in individuals without diabetes

scientific article

Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk

scientific article

Genome-wide associations for birth weight and correlations with adult disease

scientific article

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function

scientific article

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

scientific article

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

scientific article published on 13 October 2017

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

scientific article

Genome-wide meta-analysis of common variant differences between men and women

scientific article published on 27 July 2012

Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci

scientific article

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

scientific article published on February 2016

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genome-wide profiling of blood pressure in adults and children

scientific article published on 27 December 2011

Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk

scientific journal article

Genomewide association studies of stroke

scientific article published on 15 April 2009

Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

article

Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

scientific article published on 11 May 2020

Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium

scientific article

Gremlin 1, Frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis

scientific article published on 01 October 2012

Health in children: a conceptual framework for use in healthy ageing research

scientific article

Heritability and Genome-Wide Association Analyses of Sleep Duration in Children: The EAGLE Consortium

scientific article published on 19 August 2016

Heritability of fasting glucose levels in a young genetically isolated population

scientific article published on 8 February 2006

High bone mineral density and fracture risk in type 2 diabetes as skeletal complications of inadequate glucose control: the Rotterdam Study

scientific article published on 11 January 2013

High prevalence of vertebral fractures despite normal bone mineral density in patients with long-term controlled acromegaly

scholarly article by M J E Wassenaar et al published April 2011 in European Journal of Endocrinology

How to deal with the early GWAS data when imputing and combining different arrays is necessary

scientific article

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Hunting osteoporosis susceptibility genes: bigger is better but diverse is also welcome ⬇️

scientific article published on September 22, 2012

Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis.

scientific article published on 4 September 2017

Identification of a common variant at the NOS1AP locus strongly associated to QT-interval duration

scientific article published on 16 October 2008

Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals

scientific article

Identification of genetic loci associated with Helicobacter pylori serologic status

scientific article published in May 2013

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study ⬇️

scientific article published on July 3, 2012

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease

scientific article

Identifying genetic risk factors for osteoporosis.

scientific article

Impact of inherited genetic variants associated with lipid profile, hypertension, and coronary artery disease on the risk of intracranial and abdominal aortic aneurysms

scientific article published on 9 May 2013

Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'.

scientific article published on 4 June 2014

Improving accuracy of rare variant imputation with a two-step imputation approach

scientific article

Infant dietary patterns and bone mass in childhood: the Generation R Study.

scientific article published on 20 March 2015

Insulin-like growth factor I gene promoter polymorphism, collagen type II alpha1 (COL2A1) gene, and the prevalence of radiographic osteoarthritis: the Rotterdam Study

scientific article published on May 2004

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

scientific article published on 8 September 2012

Interactions between dietary vitamin E intake and SIRT1 genetic variation influence body mass index.

scientific article published on 24 March 2010

International Genome-Wide Association Study Consortium Identifies Novel Loci Associated With Blood Pressure in Children and Adolescents

scientific article published on 11 March 2016

Large common deletions associate with mortality at old age.

scientific article

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

scientific article

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

scientific article published in December 2015

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

scientific article published on 12 July 2017

Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis

scientific article published on March 2008

Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study

scientific article published on 3 December 2007

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: the GENOMOS study

scientific article

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

scientific article published on 10 April 2017

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function ⬇️

scientific article

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis

scientific article published on 10 December 2010

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects

scientific article published in January 2018

Loci at chromosomes 13, 19 and 20 influence age at natural menopause

scientific article

Low dietary riboflavin but not folate predicts increased fracture risk in postmenopausal women homozygous for the MTHFR 677 T allele

scientific article published in January 2008

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis

scientific article

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

scientific article published in Nature Communications

Low-frequency variation inTP53has large effects on head circumference and intracranial volume

Macronutrient intake and frailty: the Rotterdam Study

scientific article published on 14 November 2019

Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS.

scientific article

Maternal and fetal genetic contribution to gestational weight gain

article

Maternal and fetal genetic contribution to gestational weight gain.

scientific article published on 9 October 2017

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

scientific article published on 01 May 2019

Maternal dietary patterns during pregnancy and body composition of the child at age 6 y: the Generation R Study

scientific article published on 9 September 2015

Maternal first-trimester diet and childhood bone mass: the Generation R Study

scientific article

Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood

scientific article published on 07 May 2020

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

scientific article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

scientific article published on 29 April 2012

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

scientific article

Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology

scientific article published on 28 January 2015

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error

scientific article published on 29 March 2016

Meta-analysis of genome-wide association data identifies two loci influencing age at menarche

scientific article

Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22

scientific article

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

scientific article published on 11 September 2011

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process

scientific article

Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations

scientific article

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

scientific article

Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error

scientific article

Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size

scientific article published in April 2009

Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus

scientific article

Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity, pleiotropy and age-specific effects at the WNT16 locus

article published in 2012

Meta‐Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry

scientific article published on 19 March 2019

Methylation of BoneSOST, Its mRNA, and Serum Sclerostin Levels Correlate Strongly With Fracture Risk in Postmenopausal Women

article

Mild hyponatremia as a risk factor for fractures: The rotterdam study

article

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

scientific article published on 19 October 2015

Multi-functionality of computer-aided quantitative vertebral fracture morphometry analyses

scientific article published on October 2013

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

scientific article published on 21 November 2016

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

scientific article (publication date: 17 September 2013)

Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors

scientific article

Multiple loci associated with indices of renal function and chronic kidney disease

scientific journal article

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density

scientific article

NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality

scientific article published on 30 March 2017

NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium

scientific article

New Guidelines for Data Reporting and Statistical Analysis: Helping Authors With Transparency and Rigor in Research

scientific article published on 24 October 2019

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics

scientific article published on 10 January 2017

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

scientific article published on 2 December 2012

New loci associated with kidney function and chronic kidney disease

scientific article

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

scientific article published on February 2016

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error

scientific article

No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects

scientific article

Nonalcoholic Fatty Liver Disease in The Rotterdam Study: About Muscle Mass, Sarcopenia, Fat Mass, and Fat Distribution

scientific article published on 10 May 2019

Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.

scientific article published in August 2016

Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis

scientific article

Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects

scientific article published on 19 September 2012

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

scientific article published on 12 October 2020

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease

scientific article published on 05 May 2021

Osteoporosis

Osteoporosis Genes Identified by Genome-wide Association Studies

article

Osteoporotic Vertebral Fracture Prevalence Varies Widely Between Radiological Assessment Methods: The Rotterdam Study

scientific article

Osteoporotic Vertebral Fractures as Part of Systemic Disease

scientific article published on 12 September 2015

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

scientific article

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

scientific article

Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment

scientific article

Polymorphisms in genes within the IGF-axis influence antenatal and postnatal growth.

scientific article published in April 2013

Polymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites

scientific article

Polyunsaturated fatty acids and serum C-reactive protein: the Rotterdam study

scientific article published on 21 April 2015

Population genetic differentiation of height and body mass index across Europe

scientific article

Population genomics in a disease targeted primary cell model

scientific article published on 04 August 2009

Population-specific genetic variation in large sequencing data sets: why more data is still better

scientific article published on 19 July 2017

Practical operationalizations of risk factors for fracture in older women: results from two longitudinal studies

scientific article published in March 2009

Prediction model for knee osteoarthritis incidence, including clinical, genetic and biochemical risk factors

scientific article

Promoter and 3'-untranslated-region haplotypes in the vitamin d receptor gene predispose to osteoporotic fracture: the rotterdam study

scientific article

Protein intake during pregnancy and offspring body composition at 6 years: the Generation R Study

scientific article published on 4 July 2016

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

scientific article published on 24 May 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Quantitative imaging methods in osteoporosis

scientific article

Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts

scientific article

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF

scientific article

Rare coding variants and X-linked loci associated with age at menarche

scientific article

Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium

scientific article published on 6 November 2010

Replication study of chr17q25 with cerebral white matter lesion volume

scientific article published on 25 August 2011

Reproductive aging-associated common genetic variants and the risk of breast cancer

scientific article

Response to Comment on Koromani et al. Vertebral Fractures in Individuals With Type 2 Diabetes: More Than Skeletal Complications Alone. Diabetes Care 2020;43:137-144

scientific article published on 01 June 2020

Review of radiological scoring methods of osteoporotic vertebral fractures for clinical and research settings

scientific article published on 15 August 2012

Risk of Frailty in Elderly With COPD: A Population-Based Study

scientific article published on 9 September 2015

SIRT1 genetic variation and mortality in type 2 diabetes: interaction with smoking and dietary niacin

scientific article published on 10 January 2009

SIRT1 genetic variation is related to BMI and risk of obesity

scientific article published on 09 September 2009

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

scientific article published on 5 December 2016

Sarcopenia and Its Clinical Correlates in the General Population: The Rotterdam Study

scientific article published on 4 March 2018

Scheuermann's Disease: Evaluation of Radiological Criteria and Population Prevalence

scientific article

Scrutinizing the Genetic Underpinnings of Bone Strength

scientific article published on 12 October 2017

Serum C reactive protein levels and genetic variation in the CRP gene are not associated with the prevalence, incidence or progression of osteoarthritis independent of body mass index

scientific article

Serum testosterone levels in males are not associated with entrepreneurial behavior in two independent observational studies

scientific article published on 12 June 2013

Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31.

scientific article published on 13 April 2014

Sex-specific genetic effects influence variation in body composition

article

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms

scientific article published on 14 July 2016

Single Nucleotide Polymorphism Heritability of Behavior Problems in Childhood: Genome-Wide Complex Trait Analysis

scientific article

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

scientific article

Skin autofluorescence, a non-invasive biomarker for advanced glycation end-products, is associated with prevalent vertebral and major osteoporotic fractures: The Rotterdam Study

scientific article published on 28 May 2020

Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies

scientific article

Stratified medicine approaches for the treatment of musculoskeletal disorders

scientific article published on 02 June 2014

Subclinical thyroid dysfunction and fracture risk: a meta-analysis

scientific article

Sugar-containing beverage intake in toddlers and body composition up to age 6 years: the Generation R study.

scientific article published on 4 February 2015

Susceptibility to chronic mucus hypersecretion, a genome wide association study

scientific article

Systematic identification of trans eQTLs as putative drivers of known disease associations

scientific article (publication date: October 2013)

TRPV4 deficiency causes sexual dimorphism in bone metabolism and osteoporotic fracture risk.

scientific article published on 29 September 2013

Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study

scientific article published on 11 September 2016

The -1997 G/T and Sp1 polymorphisms in the collagen type I alpha1 (COLIA1) gene in relation to changes in femoral neck bone mineral density and the risk of fracture in the elderly: the Rotterdam study

scientific article published on 7 June 2007

The Association between Metabolic Syndrome, Bone Mineral Density, Hip Bone Geometry and Fracture Risk: The Rotterdam Study

scientific article published on 12 June 2015

The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance

scientific article

The Generation R Study: Biobank update 2015.

scientific article published on 21 December 2014

The Generation R Study: design and cohort update 2012.

scientific article

The Generation R Study: design and cohort update 2017

scientific article published on 09 January 2017

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The Influence of Serum Uric Acid on Bone Mineral Density, Hip Geometry, and Fracture Risk: The Rotterdam Study

scientific article published on 18 December 2015

The Musculoskeletal Knowledge Portal: Making Omics Data Useful to the Broader Scientific Community

scientific article published on 10 August 2020

The Role of Genetic Variation in Osteoporosis

The T-13910C polymorphism in the lactase phlorizin hydrolase gene is associated with differences in serum calcium levels and calcium intake

scientific article published in September 2010

The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis

scientific article

The association between lifestyle and overall health, using the frailty index

scientific article published on 13 February 2018

The association between obesity, diet quality and hearing loss in older adults

The association between plasma homocysteine levels and bone quality and bone mineral density parameters in older persons

scientific article published on 12 March 2014

The association between plasma homocysteine levels, methylation capacity and incident osteoporotic fractures

scientific article published on 21 March 2012

The case for genome-wide association studies of bone acquisition in paediatric and adolescent populations

scientific article published on 25 May 2016

The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels

scientific article

The complement component 5 gene and age-related macular degeneration

scientific article

The contribution of hip geometry to the prediction of hip osteoarthritis

scientific article published on 27 June 2013

The effect of thiazide and loop diuretics on urinary levels of free deoxypyridinoline: an osteoclastic bone-resorption marker

scientific article

The influence of an insulin-like growth factor I gene promoter polymorphism on hip bone geometry and the risk of nonvertebral fracture in the elderly: the Rotterdam Study

scientific article published on 12 April 2004

The molecular genetic architecture of self-employment

scientific article

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

scientific article (publication date: 2013)

The role of body mass index, insulin, and adiponectin in the relation between fat distribution and bone mineral density

scientific article

The transcriptional landscape of age in human peripheral blood

scientific article

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

scientific article

Three Genome-wide Association Studies and a Linkage Analysis Identify HERC2 as a Human Iris Color Gene

scientific article

Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene

scientific article

Tissue effect on genetic control of transcript isoform variation

scientific article

Trabecular Bone Score and Hip Structural Analysis in Patients With Atypical Femur Fractures

scientific article published in March 2018

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

scientific article

Twenty loci associated with bone mineral density identified by large-scale meta-analysis of genome-wide association datasets

Use of Selective Serotonin Reuptake Inhibitors and Bone Mineral Density Change: A Population-Based Longitudinal Study in Middle-Aged and Elderly Individuals

scientific article

Use of Trabecular Bone Score (TBS) as a Complementary Approach to Dual-energy X-ray Absorptiometry (DXA) for Fracture Risk Assessment in Clinical Practice

scientific article

Using Mendelian Randomization to Decipher Mechanisms of Bone Disease

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

scientific article

Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry ⬇️

scientific article published on 13 July 2009

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration

article

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration

scientific article published on 02 September 2019

Vertebral Fractures in Individuals With Type 2 Diabetes: More Than Skeletal Complications Alone

scientific article published on 28 October 2019

Vertebral Scheuermann's disease in Europe: prevalence, geographic variation and radiological correlates in men and women aged 50 and over

scientific article

Vitamin D and body composition in the elderly

scientific article published on 14 May 2016

Vitamin D and risk of pregnancy related hypertensive disorders: mendelian randomisation study.

scientific article

Vitamin D receptor gene BsmI and TaqI polymorphisms and fracture risk: A meta-analysis

article

Vitamin D receptor gene haplotype is associated with body height and bone size

scientific article published on 9 January 2007

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

scientific article published in July 2012

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

article

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

scientific article published on 23 May 2017

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture

scientific article

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