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List of works by Florian Kronenberg

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A comprehensive map of single base polymorphisms in the hypervariable LPA Kringle IV-2 copy number variation region

scientific article published on 09 November 2018

A genome scan for loci influencing anti-atherogenic serum bilirubin levels

scientific article published on 01 September 2002

A genome-wide analysis of DNA methylation identifies a novel association signal for Lp(a) concentrations in the LPA promoter

scientific article published on 28 April 2020

A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms

scientific article published on 16 May 2017

A genome-wide association study of metabolic traits in human urine

scientific article

A genome-wide perspective of genetic variation in human metabolism

scientific article

A simple score predicts future cardiovascular events in an inception cohort of dialysis patients

scientific article published on 14 June 2006

APOA5 variants and metabolic syndrome in Caucasians

scientific article published on 3 September 2007

APOL1 variants and kidney disease. There is no such thing as a free lunch ⬇️

scientific article published on 07 January 2011

Adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) deficiencies affect expression of lipolytic activities in mouse adipose tissues

scientific article

Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression

scientific article

An Epidemiological Study of Hemodialysis Patients Based on the European Fresenius Medical Care Hemodialysis Network: Results of the ARO Study

scientific article published on 10 December 2010

An optimized procedure for the design and evaluation of Ecotilling assays

scientific article

Ankle-Brachial Index and Peripheral Arterial Disease

Apolipoprotein A-IV Is an Independent Predictor of Disease Activity in Patients with Inflammatory Bowel Disease

scientific article published on 01 April 2007

Apolipoprotein A-IV predicts progression of chronic kidney disease: the mild to moderate kidney disease study

scientific article published on 28 December 2005

Apolipoprotein(a) isoform-specific changes of lipoprotein(a) after kidney transplantation

scientific article published in September 2003

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

scientific article published on 23 December 2011

Association between the UGT1A1*28 allele, bilirubin levels, and coronary heart disease in the Framingham Heart Study.

scientific article

Association of HbA1c values with mortality and cardiovascular events in diabetic dialysis patients. The INVOR study and review of the literature

scientific article

Association of STR polymorphisms in CMA1 and IL-4 with asthma and atopy: The SAPALDIA Cohort

article

Association of bilirubin with cardiovascular outcomes: more hype than substance?

scientific article published on August 2010

Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD.

scientific article

Association of long-term exposure to traffic-related PM10 with heart rate variability and heart rate dynamics in healthy subjects

scientific article published on 01 February 2019

Association of the 103I MC4R allele with decreased body mass in 7937 participants of two population based surveys

scientific article published in April 2005

Associations between genetic risk variants for kidney diseases and kidney disease etiology.

scientific article published on 24 October 2017

Associations of estimated glomerular filtration rate and albuminuria with mortality and renal failure by sex: a meta-analysis ⬇️

scientific article published on January 29, 2013

Authors' ResponseCorrelation between baseline telomere length and shortening over time—spurious or true?

article by Anita Kloss-Brandstätter et al published 22 December 2010 in International Journal of Epidemiology

B-type natriuretic peptide concentrations predict the progression of nondiabetic chronic kidney disease: the Mild-to-Moderate Kidney Disease Study

scientific article

Baseline and on-statin treatment lipoprotein(a) levels for prediction of cardiovascular events: individual patient-data meta-analysis of statin outcome trials

scientific article published in The Lancet

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus

scientific article published on 10 February 2013

CONAN: copy number variation analysis software for genome-wide association studies

scientific article

CUBN is a gene locus for albuminuria

scientific article

Calculated renal function: benefits and problems of the "Modification of Diet in Renal Disease" (MDRD) formula

scientific article

Carotid plaques and their predictive value for cardiovascular disease and all-cause mortality in hemodialysis patients considering renal transplantation: a decade follow-up

scientific article

Cellular aging reflected by leukocyte telomere length predicts advanced atherosclerosis and cardiovascular disease risk

scientific article published on 27 May 2010

Characterization of the vitamin E-binding properties of human plasma afamin

scientific article

Cigarette smoking and chronic allograft nephropathy

scientific article published on 21 May 2007

Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals

scientific article

Cloudgene: a graphical execution platform for MapReduce programs on private and public clouds

scientific article

Common variants in Mendelian kidney disease genes and their association with renal function

scientific article published on 12 September 2013

Conditional linkage and genome-wide association studies identify UGT1A1 as a major gene for anti-atherogenic serum bilirubin levels--the Framingham Heart Study.

scientific article published on 19 March 2009

DNA Methylation in Inflammatory Pathways Modifies the Association between BMI and Adult-Onset Non-Atopic Asthma

scientific article published on 19 February 2019

DNA methylation of lipid-related genes affects blood lipid levels

scientific article published on 12 January 2015

DNA methylation-based measures of biological age: meta-analysis predicting time to death

scientific article

Decrease of Lp(a) during weight reduction in obese children is modified by the apo(a) kringle-IV copy number variation.

scientific article published on 28 July 2009

Decrease of plasma apolipoprotein A-IV during weight reduction in obese adolescents on a low fat diet

scientific article published on 01 November 2004

Delayed in vivo catabolism of intermediate-density lipoprotein and low-density lipoprotein in hemodialysis patients as potential cause of premature atherosclerosis

scientific article

Delivering bioinformatics MapReduce applications in the cloud

Differences between human plasma and serum metabolite profiles

scientific article

Different genes interact with particulate matter and tobacco smoke exposure in affecting lung function decline in the general population

scientific article (publication date: 2012)

Discovery of sexual dimorphisms in metabolic and genetic biomarkers

scientific article

Emerging risk factors and markers of chronic kidney disease progression

scientific article published in December 2009

Epidemiologic evidence of barometric pressure changes inducing increased reporting of oral pain

scientific article

Epidemiology of dialysis patients and heart failure patients

scientific article

Estimating the single nucleotide polymorphism genotype misclassification from routine double measurements in a large epidemiologic sample

scientific article

Evaluating the Causal Relation of ApoA-IV with Disease-Related Traits - A Bidirectional Two-sample Mendelian Randomization Study

scientific article

Evaluation of gene-obesity interaction effects on cholesterol levels: a genetic predisposition score on HDL-cholesterol is modified by obesity

scientific article published on 21 September 2012

Evidence for genetic heterogeneity in lymphedema-cholestasis syndrome

scientific article

Fibroblast Growth Factor 23 (FGF23) Predicts Progression of Chronic Kidney Disease: The Mild to Moderate Kidney Disease (MMKD) Study

scientific article published on 26 July 2007

Fifteen-Year Follow-up of Association Between Telomere Length and Incident Cancer and Cancer Mortality ⬇️

scientific article published on 01 July 2011

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic associations with lipoprotein subfractions provide information on their biological nature

scientific article

Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium

scientific article published on 2 February 2012

Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins

scientific article published on 03 September 2009

Genetic polymorphisms of the main transcription factors for adiponectin gene promoter in regulation of adiponectin levels: association analysis in three European cohorts

scientific article

Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans

scientific article published on 20 January 2020

Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease

scientific article published on 8 July 2009

Genetic variation in HDL-related genes and the association with cardiovascular disease: HDL particles as chameleons of lipoprotein metabolism

article

Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum

scientific article

Genetics of serum urate concentrations and gout in a high-risk population, patients with chronic kidney disease

scientific article published in Scientific Reports

Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms

scientific article published on 15 March 2018

Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes.

scientific article

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

scientific article published in Nature Communications

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

scientific article

Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions

scientific article published on October 2008

Genome-wide association and functional follow-up reveals new loci for kidney function

scientific article

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

scientific article

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genome-wide association study of kidney function decline in individuals of European descent

scientific article

Genome-wide association study of lung function decline in adults with and without asthma

scientific article published on 16 March 2012

HaploGrep: a fast and reliable algorithm for automatic classification of mitochondrial DNA haplogroups.

scientific article published on 16 November 2010

Haplotype misclassification resulting from statistical reconstruction and genotype error, and its impact on association estimates

scientific article published on 22 July 2010

How about the uncertainty in the haplotypes in the population-based KORA studies?

scientific article

How healthy are your vessels? – Check your urine!

scientific article published on 29 September 2011

Human metabolic individuality in biomedical and pharmaceutical research

scientific article (publication date: 31 August 2011)

In vivo stable-isotope kinetic study suggests intracellular assembly of lipoprotein(a)

scientific article published on 05 October 2012

In vivo turnover study demonstrates diminished clearance of lipoprotein(a) in hemodialysis patients

scientific article published on 14 February 2007

Increased plasma amylin in type 1 diabetic patients after kidney and pancreas transplantation: A sign of impaired beta-cell function?

scientific article published in May 2006

Increased plasma concentrations of LDL-unbound apo(a) in patients with end-stage renal disease: Rapid Communication ⬇️

scientific article published on 01 December 1997

Increased serum lipoprotein(a) concentrations and low molecular weight phenotypes of apolipoprotein(a) are associated with symptomatic peripheral arterial disease

scientific article published on 24 May 2007

Influence of Polymorphisms in Genes Encoding for Insulin-Like Growth Factor (IGF)-I, Insulin, and IGF-Binding Protein (IGFBP)-3 on IGF-I, IGF-II, and IGFBP-3 Levels in Umbilical Cord Plasma ⬇️

scientific article published on June 22, 2012

Influences on the reduction of relative telomere length over 10 years in the population-based Bruneck Study: introduction of a well-controlled high-throughput assay

scientific article published on 7 August 2009

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

scientific article published on 8 September 2012

Interaction of time-varying albumin and phosphorus on mortality in incident dialysis patients

scientific article

Investigation and functional characterization of rare genetic variants in the adipose triglyceride lipase in a large healthy working population

scientific article

Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index

scientific article

Jordan’s anomaly in a case of Chanarin-Dorfman syndrome

scientific article published on 21 June 2011

Joubert-like syndrome unlinked to known candidate loci

scientific article published in February 2004

Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study

scientific article published in 2008

Lipoprotein metabolism and lipid management in chronic kidney disease.

scientific article published on 14 March 2007

Lipoprotein(a) and incident type-2 diabetes: results from the prospective Bruneck study and a meta-analysis of published literature.

scientific article published on 21 March 2017

Lipoprotein(a) as a Predictor of Cardiovascular Disease in a Prospectively Followed Cohort of Patients With Type 1 Diabetes

scientific article published on 01 July 2006

Lipoprotein(a): resurrected by genetics

scientific article

Long-Term Mortality and Incidence of Renal Dialysis and Transplantation in Type 1 Diabetes Mellitus

scientific article published on 01 August 2006

Long-term effects of air pollution on ankle-brachial index

scientific article published on 26 May 2018

Look beyond one's own nose: combination of information from publicly available sources reveals an association of GATA4 polymorphisms with plasma triglycerides

scientific article

Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts

scientific article published on 2 February 2011

Lysis reagents, cell numbers, and calculation method influence high-throughput measurement of HDL-mediated cholesterol efflux capacity

scientific article published on 25 September 2021

Macro- and microcirculatory assessment of cold sensitivity after traumatic finger amputation and microsurgical replantation

scientific article published on 20 January 2007

Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts

scientific article published on 27 April 2011

Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

scientific article published on 23 October 2009

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

scientific article published on 30 October 2020

Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting

scientific article (publication date: 11 November 2010)

Microcirculatory assessment of vascular acrosyndrome in anorexia nervosa and analysis of manifestation factors

scientific article published in January 2004

Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus

scientific article

Mitochondrial DNA copy number is associated with all-cause mortality and cardiovascular events in patients with peripheral arterial disease

scientific article published on 09 February 2020

Neuropathic pain after femoropopliteal bypass surgery

scientific article published on 01 June 2004

New loci associated with kidney function and chronic kidney disease

scientific article

No association of two functional polymorphisms in human ALOX15 with myocardial infarction

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation

scientific article published on 20 March 2020

On the impact of different approaches to classify age-related macular degeneration: Results from the German AugUR study.

scientific article

Oxidized phospholipids predict the presence and progression of carotid and femoral atherosclerosis and symptomatic cardiovascular disease: five-year prospective results from the Bruneck study

scientific article

Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: prospective results from the Bruneck study

scientific article

Plasma Concentrations of Afamin Are Associated With Prevalent and Incident Type 2 Diabetes: A Pooled Analysis in More Than 20,000 Individuals

scientific article published on 6 September 2017

Plasma distribution of apoA-IV in patients with coronary artery disease and healthy controls

scientific article published on 01 June 2003

Plasmid-normalized quantification of relative mitochondrial DNA copy number

scientific article published in Scientific Reports

Polymorphisms in the gene regions of the adaptor complex LAMTOR2/LAMTOR3 and their association with breast cancer risk

scientific article

Prediction of cardiovascular risk by Lp(a) concentrations or genetic variants within the LPA gene region

scientific article published on 01 April 2019

Predictive performance of renal function equations for patients with chronic kidney disease and normal serum creatinine levels.

scientific article

Prevalence and progression of peripheral arterial calcifications in patients with ESRD.

scientific article published in January 2003

Pro-A-type natriuretic peptide and pro-adrenomedullin predict progression of chronic kidney disease: the MMKD Study

scientific article published on 3 December 2008

Profiling of Mitochondrial DNA Heteroplasmy in a Prospective Oral Squamous Cell Carcinoma Study

scientific article published on 17 July 2020

Protein markers and risk of type 2 diabetes and prediabetes: a targeted proteomics approach in the KORA F4/FF4 study

scientific article published on 31 December 2018

Proteinuria and hemoglobin levels in patients with primary glomerular disease

scientific article published in September 2005

Proteinuria and plasma total homocysteine levels in chronic renal disease patients with a normal range serum creatinine: critical impact of true glomerular filtration rate ⬇️

scientific article published on November 1, 2001

Raising the bar on telomere epidemiology

scientific article published on 8 January 2010

Rapid activation of the complement system by cuprophane depends on complement component C4 ⬇️

scientific article published on 01 April 1998

Re-evaluation of the penicillamine challenge test in the diagnosis of Wilson’s disease in children

scientific article published on 04 April 2007

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Reproductive factors and its association with peripheral arterial disease in women aged 52-81 years: the KORA F4 study

scientific article published on 5 February 2013

SERPINA1 PiZ and PiS heterozygotes and lung function decline in the SAPALDIA cohort

scientific article

SNPflow: a lightweight application for the processing, storing and automatic quality checking of genotyping assays.

scientific article

Sample selection algorithm to improve quality of genotyping from plasma-derived DNA: to separate the wheat from the chaff

scientific article

Segregation analysis of HDL cholesterol in the NHLBI Family Heart Study and in Utah pedigrees.

scientific article

Serum bilirubin levels, UGT1A1 polymorphisms and risk for coronary artery disease

scientific article published on 26 August 2008

Sex and age interaction with genetic association of atherogenic uric acid concentrations

scientific article

Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI

scientific article

Sex-specific association of time-varying haemoglobin values with mortality in incident dialysis patients.

scientific article published on 26 February 2010

Somatic mutations throughout the entire mitochondrial genome are associated with elevated PSA levels in prostate cancer patients.

scientific article published on December 2010

Statin treatment increases lipoprotein(a) levels in subjects with low molecular weight apolipoprotein(a) phenotype

scientific article published on 03 July 2019

Structure, function, and genetics of lipoprotein (a).

scientific article published on 13 April 2016

TNFalpha- and NF-kappaB-dependent induction of the chemokine CCL1 in human macrophages exposed to the atherogenic lipoprotein(a).

scientific article published on 2 February 2009

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

scientific article published on 02 October 2019

The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes

scientific article

The German Chronic Kidney Disease (GCKD) study: design and methods

scientific article published on 22 August 2011

The adiponectin gene is associated with adiponectin levels but not with characteristics of the insulin resistance syndrome in healthy Caucasians

article

The association of mid-regional pro-adrenomedullin and mid-regional pro-atrial natriuretic peptide with mortality in an incident dialysis cohort

scientific article (publication date: 7 March 2011)

The association of relative telomere length with symptomatic peripheral arterial disease: Results from the CAVASIC study ⬇️

scientific article published on June 10, 2013

The challenges of measuring Lp(a): A fight against Hydra?

scientific article published on 31 August 2019

The evaporation of positive genetic association findings. When time has come to go ⬇️

scientific article published on August 13, 2010

The power of genetic diversity in genome-wide association studies of lipids

The satiety factor apolipoprotein A-IV modulates intestinal epithelial permeability through its interaction with alpha-catenin: implications for inflammatory bowel diseases

scientific article published on August 2007

Therapeutic lowering of lipoprotein(a): How much is enough?

scientific article published on 05 July 2019

Time‐dependent lipid profile inversely associates with mortality in hemodialysis patients – independent of inflammation/malnutrition

scientific article

eCOMPAGT -- efficient combination and management of phenotypes and genotypes for genetic epidemiology

scientific article

eCOMPAGT integrates mtDNA: import, validation and export of mitochondrial DNA profiles for population genetics, tumour dynamics and genotype-phenotype association studies

scientific article

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