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List of works by Andréa Dessen

A PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibiotics

scientific article

A bacterial protein targets the BAHD1 chromatin complex to stimulate type III interferon response

scientific article

A boronic-acid-based probe for fluorescence polarization assays with penicillin binding proteins and β-lactamases

scientific article published on 26 August 2011

A new catalytic dyad regulates anchoring of molecules to the Gram-positive cell wall by sortases

scientific article

A structural snapshot of type II pilus formation in Streptococcus pneumoniae

scientific article

Active site restructuring regulates ligand recognition in class A penicillin-binding proteins

scientific article

An RNA-Binding Protein Secreted by a Bacterial Pathogen Modulates RIG-I Signaling

scientific article published on 21 November 2019

Assembly of a rod-shaped chimera of a trimeric GCN4 zipper and the HIV-1 gp41 ectodomain expressed in Escherichia coli.

scientific article

Assembly of an atypical α-macroglobulin complex from Pseudomonas aeruginosa.

scientific article published on 11 January 2018

Atomic structure of the ectodomain from HIV-1 gp41

scientific article

Bacterial secretins: Mechanisms of assembly and membrane targeting

scientific article published on 19 February 2020

Bifunctional penicillin-binding proteins: focus on the glycosyltransferase domain and its specific inhibitor moenomycin

scientific article

Biogenesis, regulation, and targeting of the type III secretion system

scientific article published on May 2011

Bridging cell wall biosynthesis and bacterial morphogenesis.

scientific article published on 26 October 2010

Calcium-dependent complex formation between PBP2 and lytic transglycosylase SltB1 of Pseudomonas aeruginosa

scientific article

Characterization of the elongasome core PBP2 : MreC complex of Helicobacter pylori

scientific article published on 15 September 2011

Common alterations in PBP1a from resistant Streptococcus pneumoniae decrease its reactivity toward beta-lactams: structural insights

scientific article

Complex Formation between Mur Enzymes from Streptococcus pneumoniae

scientific article published on 15 July 2019

Conformational states of a bacterial α2-macroglobulin resemble those of human complement C3.

scientific article

Crystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutations

scientific article

Crystal structure of a peptidoglycan synthesis regulatory factor (PBP3) from Streptococcus pneumoniae

scientific article published on 13 December 2004

Crystal structure of human cytosolic phospholipase A2 reveals a novel topology and catalytic mechanism

scientific article

Crystal structure of human otubain 2.

scientific article

Crystal structure of penicillin-binding protein 1a (PBP1a) reveals a mutational hotspot implicated in beta-lactam resistance in Streptococcus pneumoniae

scientific article published on 9 November 2005

Crystallization and preliminary X-ray analysis of the matrix protein from Ebola virus

scientific article published on June 2000

Crystallographic Study of Peptidoglycan Biosynthesis Enzyme MurD: Domain Movement Revisited

scientific article

Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2,4-dione inhibitors of MurD ligase

scientific article

Dual Inhibitor of MurD and MurE Ligases from Escherichia coli and Staphylococcus aureus.

scientific article

FtsZ filament capping by MciZ, a developmental regulator of bacterial division.

scientific article published on 6 April 2015

Functional characterization of penicillin-binding protein 1b from Streptococcus pneumoniae

scientific article

Hijacking of the pleiotropic cytokine interferon-γ by the type III secretion system of Yersinia pestis

scientific article

In this issue

Membrane and Chaperone Recognition by the Major Translocator Protein PopB of the Type III Secretion System of Pseudomonas aeruginosa

scientific article

Membrane targeting and pore formation by the type III secretion system translocon

scientific article published on 23 December 2010

Molecular architecture of the PBP2-MreC core bacterial cell wall synthesis complex.

scientific article published on 3 October 2017

Molecular mechanisms of antibiotic resistance in gram-positive pathogens.

scientific article

MreB and MurG as scaffolds for the cytoplasmic steps of peptidoglycan biosynthesis

scientific article

New 5-benzylidenethiazolidin-4-one inhibitors of bacterial MurD ligase: design, synthesis, crystal structures, and biological evaluation

scientific article

New approaches towards the identification of antibiotic and vaccine targets in Streptococcus pneumoniae.

scientific article

New strategies for targeting and treatment of multi-drug resistant Staphylococcus aureus

scientific article

Novel naphthalene-N-sulfonyl-D-glutamic acid derivatives as inhibitors of MurD, a key peptidoglycan biosynthesis enzyme

scientific article

Oligomerization of type III secretion proteins PopB and PopD precedes pore formation in Pseudomonas

scientific article published on October 2003

PBP active site flexibility as the key mechanism for beta-lactam resistance in pneumococci

scientific article

Penicillin binding proteins: key players in bacterial cell cycle and drug resistance processes.

scientific article published on September 2006

Penicillin-Binding Proteins (PBPs) and Bacterial Cell Wall Elongation Complexes

scientific article published on 01 January 2019

Phospholipase A(2) enzymes: structural diversity in lipid messenger metabolism.

scientific article

Pilotin-secretin recognition in the type II secretion system of Klebsiella oxytoca

scientific article

Pore-forming activity of the Pseudomonas aeruginosa type III secretion system translocon alters the host epigenome

scientific article

Primary structure and crystallization of orotate phosphoribosyltransferase from Salmonella typhimurium

scientific article published in April 1993

Resistance to antibiotics targeted to the bacterial cell wall

scientific article

Second-generation sulfonamide inhibitors of D-glutamic acid-adding enzyme: activity optimisation with conformationally rigid analogues of D-glutamic acid

scientific article

Self-association of MreC as a regulatory signal in bacterial cell wall elongation

scientific article published on 20 May 2021

Solution X-ray scattering study of a full-length class A penicillin-binding protein

scientific article published on 07 January 2011

Sortase activity is controlled by a flexible lid in the pilus biogenesis mechanism of gram-positive pathogens

scientific article

Sortase-mediated pilus fiber biogenesis in Streptococcus pneumoniae

scientific article

Specificity Determinants for Lysine Incorporation in Staphylococcus aureus Peptidoglycan as Revealed by the Structure of a MurE Enzyme Ternary Complex

scientific article

Stability and assembly of pilus subunits of Streptococcus pneumoniae

scientific article

Structural Basis for the Inhibition of the Chromatin Repressor BAHD1 by the Bacterial Nucleomodulin LntA

scientific article

Structural Basis of Chaperone Recognition of Type III Secretion System Minor Translocator Proteins

scientific article

Structural Basis of Lipid Targeting and Destruction by the Type V Secretion System of Pseudomonas aeruginosa

scientific article

Structural Basis of Pilus Anchoring by the Ancillary Pilin RrgC of Streptococcus pneumoniae

scientific article

Structural Insights into Protein-Protein Interactions Involved in Bacterial Cell Wall Biogenesis

scientific article

Structural and Functional Characterization of the Type Three Secretion System (T3SS) Needle of

scientific article published on 29 March 2019

Structural and functional characterization of enantiomeric glutamic acid derivatives as potential transition state analogue inhibitors of MurD ligase

scientific article

Structural and mechanistic basis of penicillin-binding protein inhibition by lactivicins

scientific article

Structural basis of cytotoxicity mediated by the type III secretion toxin ExoU from Pseudomonas aeruginosa

scientific article (publication date: 2012)

Structural basis of eukaryotic cell targeting by type III secretion system (T3SS) effectors.

scientific article published on 26 March 2013

Structural basis of host cell recognition by the pilus adhesin from Streptococcus pneumoniae

scientific article

Structural biology of protein functional regulation ⬇️

scientific article published on November 19, 2010

Structural characterization and membrane binding properties of the matrix protein VP40 of Ebola virus

scientific article published on June 2000

Structural characterization and membrane localization of ExsB from the type III secretion system (T3SS) of Pseudomonas aeruginosa

scientific article

Structural similarity of secretins from type II and type III secretion systems

scientific article

Structural studies of the transpeptidase domain of PBP1a from Streptococcus pneumoniae

scientific article published on 23 May 2003

Structure and assembly of pilotin-dependent and -independent secretins of the type II secretion system.

scientific article published on 13 May 2019

Structure and mechanism of human cytosolic phospholipase A(2).

scientific article

Structure of a bacterial α2-macroglobulin reveals mimicry of eukaryotic innate immunity

scientific article

Structure of a widely conserved type IV pilus biogenesis factor that affects the stability of secretin multimers

scientific article

Structure of internalin InlK from the human pathogen Listeria monocytogenes

scientific article

Structure of the heterotrimeric complex that regulates type III secretion needle formation

scientific article

Structure-activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF

scientific article published in August 2013

Structure-based design of a new series of D-glutamic acid based inhibitors of bacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (MurD)

scientific article

Structure-guided design of cell wall biosynthesis inhibitors that overcome β-lactam resistance in Staphylococcus aureus (MRSA)

scientific article

Structure/function analysis of Neisseria meningitidis PilW, a conserved protein that plays multiple roles in type IV pilus biology

scientific article

The MurG glycosyltransferase provides an oligomeric scaffold for the cytoplasmic steps of peptidoglycan biosynthesis in the human pathogen Bordetella pertussis

scientific article published on 15 March 2019

The PscE-PscF-PscG complex controls type III secretion needle biogenesis in Pseudomonas aeruginosa

scientific article published on 22 August 2005

The SciZ protein anchors the enteroaggregative Escherichia coli Type VI secretion system to the cell wall

scientific article published on February 2010

The V antigen of Pseudomonas aeruginosa is required for assembly of the functional PopB/PopD translocation pore in host cell membranes

scientific article published on August 2004

The glycosyltransferase domain of penicillin-binding protein 2a from Streptococcus pneumoniae catalyzes the polymerization of murein glycan chains

scientific article published on August 2003

The matrix protein VP40 from Ebola virus octamerizes into pore-like structures with specific RNA binding properties

scientific article (publication date: April 2003)

Trapping of an acyl-enzyme intermediate in a penicillin-binding protein (PBP)-catalyzed reaction

scientific article published in November 2007

Two crystal structures of pneumococcal pilus sortase C provide novel insights into catalysis and substrate specificity

scientific article

Type III secretion proteins PcrV and PcrG from Pseudomonas aeruginosa form a 1:1 complex through high affinity interactions

scientific article

Type III secretion system translocator has a molten globule conformation both in its free and chaperone-bound forms

scientific article published on 18 June 2007

Unique features of a Pseudomonas aeruginosa α2-macroglobulin homolog.

scientific article published on 06 August 2013

X-Ray Crystal Structure of HLA-DR4 (DRA*0101, DRB1*0401) Complexed with a Peptide from Human Collagen II ⬇️

scientific article published on October 1, 1997

X-ray Crystallographic Studies of Unique Cross-Linked Lattices between Four Isomeric Biantennary Oligosaccharides and Soybean Agglutinin, ⬇️

scientific article published on December 9, 1997

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