List of works - Bruno Coutard

3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects against Picornaviruses

scientific article

A second, non-canonical RNA-dependent RNA polymerase in SARS Coronavirus

scientific article

Assessment of Dengue virus helicase and methyltransferase as targets for fragment-based drug discovery

scientific article

Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex

scientific article

Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein

scientific article

Delayed Laboratory Response to COVID-19 Caused by Molecular Diagnostic Contamination

scientific article published on 20 May 2020

Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design

scientific article

Evidence for novel hepaciviruses in rodents

scientific article published in 2013

Flavivirus NS3 and NS5 proteins interaction network: a high-throughput yeast two-hybrid screen

scientific journal article

Functional Characterization of the Cleavage Specificity of the Sapovirus Chymotrypsin-Like Protease

scientific article (publication date: August 2008)

Preliminary characterization of (nucleoside-2′-O-)-methyltransferase crystals from Meaban and Yokose flaviviruses

scientific article (publication date: August 2006)

Preliminary crystallographic characterization of an RNA helicase from Kunjin virus

scientific article

Purification and crystallization of Kokobera virus helicase

scientific article

Recognition of RNA cap in the Wesselsbron virus NS5 methyltransferase domain: implications for RNA-capping mechanisms in Flavivirus

scientific article

Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C

scientific article (publication date: May 2016)

Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93

scientific article

Structural and biochemical analysis of human pathogenic astrovirus serine protease at 2.0 A resolution

scientific article

Structural characterization of the N-terminal part of the MERS-CoV nucleocapsid by X-ray diffraction and small-angle X-ray scattering

scientific article

Structure and biochemical analysis of Kokobera virus helicase

scientific article

Structure and functionality in flavivirus NS-proteins: perspectives for drug design

scientific article

Structure of the C-terminal domain of nsp4 from feline coronavirus

scientific article

Structure of the X (ADRP) domain of nsp3 from feline coronavirus

scientific article

Structure of the methyltransferase domain from the Modoc virus, a flavivirus with no known vector

scientific article

The Crystal Structure of a Cardiovirus RNA-Dependent RNA Polymerase Reveals an Unusual Conformation of the Polymerase Active Site

scientific article

The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket

scientific article (publication date: July 2009)

The N-Terminal Domain of the Arenavirus L Protein Is an RNA Endonuclease Essential in mRNA Transcription

scientific article

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family

scientific article

The Zika virus methyltransferase: structure and functions for drug design perspectives

scientific article (publication date: 28 December 2016)

The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases

scientific article

The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes

scientific article

mRNA Capping by Venezuelan Equine Encephalitis Virus nsP1: Functional Characterization and Implications for Antiviral Research

scientific article

List of works by Bruno Coutard

3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects against Picornaviruses

A second, non-canonical RNA-dependent RNA polymerase in SARS Coronavirus

Assessment of Dengue virus helicase and methyltransferase as targets for fragment-based drug discovery

Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex

Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein

Delayed Laboratory Response to COVID-19 Caused by Molecular Diagnostic Contamination

Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design

Evidence for novel hepaciviruses in rodents

Flavivirus NS3 and NS5 proteins interaction network: a high-throughput yeast two-hybrid screen

Functional Characterization of the Cleavage Specificity of the Sapovirus Chymotrypsin-Like Protease

Preliminary characterization of (nucleoside-2′-O-)-methyltransferase crystals from Meaban and Yokose flaviviruses

Preliminary crystallographic characterization of an RNA helicase from Kunjin virus

Purification and crystallization of Kokobera virus helicase

Recognition of RNA cap in the Wesselsbron virus NS5 methyltransferase domain: implications for RNA-capping mechanisms in Flavivirus

Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C

Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93

Structural and biochemical analysis of human pathogenic astrovirus serine protease at 2.0 A resolution

Structural characterization of the N-terminal part of the MERS-CoV nucleocapsid by X-ray diffraction and small-angle X-ray scattering

Structure and biochemical analysis of Kokobera virus helicase

Structure and functionality in flavivirus NS-proteins: perspectives for drug design

Structure of the C-terminal domain of nsp4 from feline coronavirus

Structure of the X (ADRP) domain of nsp3 from feline coronavirus

Structure of the methyltransferase domain from the Modoc virus, a flavivirus with no known vector

The Crystal Structure of a Cardiovirus RNA-Dependent RNA Polymerase Reveals an Unusual Conformation of the Polymerase Active Site

The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket

The N-Terminal Domain of the Arenavirus L Protein Is an RNA Endonuclease Essential in mRNA Transcription

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family

The Zika virus methyltransferase: structure and functions for drug design perspectives

The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases

The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes

mRNA Capping by Venezuelan Equine Encephalitis Virus nsP1: Functional Characterization and Implications for Antiviral Research