List of works - Mark Cushman

A structure-based model of the reaction catalyzed by lumazine synthase from Aquifex aeolicus

scientific article (publication date: 18 April 2003)

Application of Sequential Palladium Catalysis for the Discovery of Janus Kinase Inhibitors in the Benzo[ c]pyrrolo[2,3- h][1,6]naphthyridin-5-one (BPN) Series

scientific article published on 21 November 2018

Crystallographic Study of a Novel Subnanomolar Inhibitor Provides Insight on the Binding Interactions of Alkenyldiarylmethanes with Human Immunodeficiency Virus-1 Reverse Transcriptase

scientific article

Design and Synthesis of Chlorinated and Fluorinated 7-Azaindenoisoquinolines as Potent Cytotoxic Anticancer Agents That Inhibit Topoisomerase I.

scientific article

Design, Synthesis, and Biological Evaluation of Potent Quinoline and Pyrroloquinoline Ammosamide Analogues as Inhibitors of Quinone Reductase 2

scientific article

Design, synthesis, and biological evaluation of antiviral agents targeting flavivirus envelope proteins

scientific article

Design, synthesis, and biological evaluation of thiazoles targeting flavivirus envelope proteins

scientific article

Indenoisoquinoline Topoisomerase Inhibitors Strongly Bind and Stabilize the MYC Promoter G-Quadruplex and Downregulate MYC

scientific article published on 08 July 2019

Lumazine synthase from Candida albicans as an anti-fungal target enzyme: structural and biochemical basis for drug design

scientific article

MAIT Recognition of a Stimulatory Bacterial Antigen Bound to MR1

scientific article

Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by 19F NMR protein perturbation experiments

scientific article

Structural study and thermodynamic characterization of inhibitor binding to lumazine synthase fromBacillus anthracis

scientific article

Synthesis and Biological Evaluation of the First Triple Inhibitors of Human Topoisomerase 1, Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), and Tyrosyl-DNA Phosphodiesterase 2 (Tdp2).

scientific article published on 18 April 2017

Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis ⬇️

scientific article

Synthesis of Casimiroin and Optimization of Its Quinone Reductase 2 and Aromatase Inhibitory Activities

scientific article

The structural basis of riboflavin binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase

scientific article

List of works by Mark Cushman

A structure-based model of the reaction catalyzed by lumazine synthase from Aquifex aeolicus

Application of Sequential Palladium Catalysis for the Discovery of Janus Kinase Inhibitors in the Benzo[ c]pyrrolo[2,3- h][1,6]naphthyridin-5-one (BPN) Series

Crystallographic Study of a Novel Subnanomolar Inhibitor Provides Insight on the Binding Interactions of Alkenyldiarylmethanes with Human Immunodeficiency Virus-1 Reverse Transcriptase

Design and Synthesis of Chlorinated and Fluorinated 7-Azaindenoisoquinolines as Potent Cytotoxic Anticancer Agents That Inhibit Topoisomerase I.

Design, Synthesis, and Biological Evaluation of Potent Quinoline and Pyrroloquinoline Ammosamide Analogues as Inhibitors of Quinone Reductase 2

Design, synthesis, and biological evaluation of antiviral agents targeting flavivirus envelope proteins

Design, synthesis, and biological evaluation of thiazoles targeting flavivirus envelope proteins

Indenoisoquinoline Topoisomerase Inhibitors Strongly Bind and Stabilize the MYC Promoter G-Quadruplex and Downregulate MYC

Lumazine synthase from Candida albicans as an anti-fungal target enzyme: structural and biochemical basis for drug design

MAIT Recognition of a Stimulatory Bacterial Antigen Bound to MR1

Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by 19F NMR protein perturbation experiments

Structural study and thermodynamic characterization of inhibitor binding to lumazine synthase fromBacillus anthracis

Synthesis and Biological Evaluation of the First Triple Inhibitors of Human Topoisomerase 1, Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), and Tyrosyl-DNA Phosphodiesterase 2 (Tdp2).

Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis ⬇️

Synthesis of Casimiroin and Optimization of Its Quinone Reductase 2 and Aromatase Inhibitory Activities

The structural basis of riboflavin binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase