List of works - Banumathi Sankaran

2.7 Å cryo-EM structure of rotavirus core protein VP3, a unique capping machine with a helicase activity

scientific article published on 15 April 2020

A Conserved Glu–Arg Salt Bridge Connects Coevolved Motifs That Define the Eukaryotic Protein Kinase Fold ⬇️

scientific article published on November 25, 2011

A Crystal Structure of the Cyclic GMP-dependent Protein Kinase Iβ Dimerization/Docking Domain Reveals Molecular Details of Isoform-specific Anchoring* ⬇️

scientific article published on September 8, 2010

A Selection for Assembly Reveals That a Single Amino Acid Mutant of the Bacteriophage MS2 Coat Protein Forms a Smaller Virus-like Particle

scientific article

A triple mutant in the Ω-loop of TEM-1 β-lactamase changes the substrate profile via a large conformational change and an altered general base for catalysis

scientific article

Analysis of the Binding Forces Driving the Tight Interactions between -Lactamase Inhibitory Protein-II (BLIP-II) and Class A -Lactamases

scientific article

Antidotes to anthrax lethal factor intoxication. Part 3: Evaluation of core structures and further modifications to the C2-side chain

scientific article

BrabA.11339.a: anomalous diffraction and ligand binding guide towards the elucidation of the function of a `putative β-lactamase-like protein' from Brucella melitensis

scientific article

Computational design of serine hydrolases

scientific article published on 13 February 2025

Crystal Structure of Toxoplasma gondii Porphobilinogen Synthase

scientific article

Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication

scientific article

Cysteine Dioxygenase Structures from pH4 to 9: Consistent Cys-Persulfenate Formation at Intermediate pH and a Cys-Bound Enzyme at Higher pH ⬇️

scientific article published on June 7, 2013

De novo design of tunable, pH-driven conformational changes.

scientific article published on 01 May 2019

Design of stimulus-responsive two-state hinge proteins

scientific article published on 17 August 2023

Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs

scientific article

Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis

scientific article

Insights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein ⬇️

scientific article published on February 1, 2011

Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization

scientific article published on 22 September 2021

Removal of the Side Chain at the Active-Site Serine by a Glycine Substitution Increases the Stability of a Wide Range of Serine β-Lactamases by Relieving Steric Strain

scientific article

Robust deep learning–based protein sequence design using ProteinMPNN ⬇️

scientific article published on 15 September 2022

Structural Analysis of Determinants of Histo-Blood Group Antigen Binding Specificity in Genogroup I Noroviruses

scientific article

Structural Analysis of Histo-Blood Group Antigen Binding Specificity in a Norovirus GII.4 Epidemic Variant: Implications for Epochal Evolution

scientific article

Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I

scientific article

Structural Basis for Different Substrate Profiles of Two Closely Related Class D β-Lactamases and Their Inhibition by Halogens

scientific article

Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus

scientific article

Structural Insights into the Functions of TBK1 in Innate Antimicrobial Immunity

scientific article

Structural basis of Fic-mediated adenylylation

scientific article

Structural insights into RipC, a putative citrate lyase β subunit from aYersinia pestisvirulence operon ⬇️

scientific article published on December 24, 2011

Structure and Rearrangements in the Carboxy-Terminal Region of SpIH Channels

scientific article

Structure determination of LpxA from the lipopolysaccharide-synthesis pathway ofAcinetobacter baumannii ⬇️

scientific article published on November 28, 2012

Structure determination of LpxD from the lipopolysaccharide-synthesis pathway ofAcinetobacter baumannii ⬇️

scientific article published on December 25, 2012

Structure of Yeast Regulatory Subunit: A Glimpse into the Evolution of PKA Signaling ⬇️

scientific article published on November 10, 2010

Structure of an As(III) S -Adenosylmethionine Methyltransferase: Insights into the Mechanism of Arsenic Biotransformation

scientific article

Structure of fructose bisphosphate aldolase from Bartonella henselae bound to fructose 1,6-bisphosphate ⬇️

scientific article published on August 13, 2011

Structure of fructose bisphosphate aldolase from Encephalitozoon cuniculi ⬇️

scientific article published on August 13, 2011

Structure of the carboxy-terminal region of a KCNH channel ⬇️

scientific article published on January 9, 2012

Structure of the polypeptide crotamine from the Brazilian rattlesnakeCrotalus durissus terrificus

scientific article

Structure of thymidylate kinase from Ehrlichia chaffeensis ⬇️

scientific article published on August 16, 2011

Structures of a putative ζ-class glutathione S -transferase from the pathogenic fungus Coccidioides immitis

scientific article

The Structural Basis of IRF-3 Activation upon Phosphorylation

scientific article published on 21 August 2020

The structure of LpxD from Pseudomonas aeruginosa at 1.3 Å resolution ⬇️

scientific article published on June 23, 2011

X-ray Crystal Structure of the UCS Domain-Containing UNC-45 Myosin Chaperone from Drosophila melanogaster

scientific article

X-ray crystallographic analysis of the complexes of enoyl acyl carrier protein reductase of Plasmodium falciparum with triclosan variants to elucidate the importance of different functional groups in enzyme inhibition

scientific article

Zinc-Independent Folate Biosynthesis: Genetic, Biochemical, and Structural Investigations Reveal New Metal Dependence for GTP Cyclohydrolase IB

scientific article

List of works by Banumathi Sankaran

2.7 Å cryo-EM structure of rotavirus core protein VP3, a unique capping machine with a helicase activity

A Conserved Glu–Arg Salt Bridge Connects Coevolved Motifs That Define the Eukaryotic Protein Kinase Fold ⬇️

A Crystal Structure of the Cyclic GMP-dependent Protein Kinase Iβ Dimerization/Docking Domain Reveals Molecular Details of Isoform-specific Anchoring* ⬇️

A Selection for Assembly Reveals That a Single Amino Acid Mutant of the Bacteriophage MS2 Coat Protein Forms a Smaller Virus-like Particle

A triple mutant in the Ω-loop of TEM-1 β-lactamase changes the substrate profile via a large conformational change and an altered general base for catalysis

Analysis of the Binding Forces Driving the Tight Interactions between -Lactamase Inhibitory Protein-II (BLIP-II) and Class A -Lactamases

Antidotes to anthrax lethal factor intoxication. Part 3: Evaluation of core structures and further modifications to the C2-side chain

BrabA.11339.a: anomalous diffraction and ligand binding guide towards the elucidation of the function of a `putative β-lactamase-like protein' from Brucella melitensis

Computational design of serine hydrolases

Crystal Structure of Toxoplasma gondii Porphobilinogen Synthase

Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication

Cysteine Dioxygenase Structures from pH4 to 9: Consistent Cys-Persulfenate Formation at Intermediate pH and a Cys-Bound Enzyme at Higher pH ⬇️

De novo design of tunable, pH-driven conformational changes.

Design of stimulus-responsive two-state hinge proteins

Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs

Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis

Insights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein ⬇️

Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization

Removal of the Side Chain at the Active-Site Serine by a Glycine Substitution Increases the Stability of a Wide Range of Serine β-Lactamases by Relieving Steric Strain

Robust deep learning–based protein sequence design using ProteinMPNN ⬇️

Structural Analysis of Determinants of Histo-Blood Group Antigen Binding Specificity in Genogroup I Noroviruses

Structural Analysis of Histo-Blood Group Antigen Binding Specificity in a Norovirus GII.4 Epidemic Variant: Implications for Epochal Evolution

Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I

Structural Basis for Different Substrate Profiles of Two Closely Related Class D β-Lactamases and Their Inhibition by Halogens

Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus

Structural Insights into the Functions of TBK1 in Innate Antimicrobial Immunity

Structural basis of Fic-mediated adenylylation

Structural insights into RipC, a putative citrate lyase β subunit from aYersinia pestisvirulence operon ⬇️

Structure and Rearrangements in the Carboxy-Terminal Region of SpIH Channels

Structure determination of LpxA from the lipopolysaccharide-synthesis pathway ofAcinetobacter baumannii ⬇️

Structure determination of LpxD from the lipopolysaccharide-synthesis pathway ofAcinetobacter baumannii ⬇️

Structure of Yeast Regulatory Subunit: A Glimpse into the Evolution of PKA Signaling ⬇️

Structure of an As(III) S -Adenosylmethionine Methyltransferase: Insights into the Mechanism of Arsenic Biotransformation

Structure of fructose bisphosphate aldolase from Bartonella henselae bound to fructose 1,6-bisphosphate ⬇️

Structure of fructose bisphosphate aldolase from Encephalitozoon cuniculi ⬇️

Structure of the carboxy-terminal region of a KCNH channel ⬇️

Structure of the polypeptide crotamine from the Brazilian rattlesnakeCrotalus durissus terrificus

Structure of thymidylate kinase from Ehrlichia chaffeensis ⬇️

Structures of a putative ζ-class glutathione S -transferase from the pathogenic fungus Coccidioides immitis

The Structural Basis of IRF-3 Activation upon Phosphorylation

The structure of LpxD from Pseudomonas aeruginosa at 1.3 Å resolution ⬇️

X-ray Crystal Structure of the UCS Domain-Containing UNC-45 Myosin Chaperone from Drosophila melanogaster

X-ray crystallographic analysis of the complexes of enoyl acyl carrier protein reductase of Plasmodium falciparum with triclosan variants to elucidate the importance of different functional groups in enzyme inhibition

Zinc-Independent Folate Biosynthesis: Genetic, Biochemical, and Structural Investigations Reveal New Metal Dependence for GTP Cyclohydrolase IB